ΔMEP2 low ammonium

03-Feb-2014 by fellenb
multiconditional experiment no. (if not recombined):
measurement selection: {{428,429,432,433,436,437,438,439},{442,443,452,453,0,0,0,0},{446,447,450,451,0,0,0,0}}
multi-channel data:
+control (i.e. reference) at 428 429 432 433 436 437 438 439 428 429 438 439 432 433 436 437
local background: subtracted
normalization: log. reg. 2
filtering:
+filter 1: 2 1 29000 3
+on conditions: 1 1 1
+filter 2: 7 0 0.05 2
+on conditions: 0 1 1
+filter 3: 0 1 NaN 3
+on conditions: 0 1 1
correspondence analysis:
+feeding: log of flatprim, flatsecu
+hybs: mass to median of each condition only
+genes: restricted by geneorder (you picked 3087)
selection (asterisk in first column): represents filtering
intensity threshold for pvalue-based color code: 29000


factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
1938_____________ +1.05 +1.050.1830.1050.4471305813655137086.2____hypotheticalprotein
*193467___________ +1.59 +1.640.0030.0070.0111354721500222066.498__RNasePa
*195741___________ +8.31 +9.890.0000.0000.000283912359522808096.1116_conserv
*19775____________ +1.22 +1.150.0280.0400.0622352028696271466.1671_vacuolartargetingprotein
*192820___________ +1.74 +1.830.0010.0040.0041845532174337906.2208_hypothe
*192709___________ +3.24 +3.810.0000.0010.0002063466755787036.2725_zuotin,aputativeZ-DNAbindingprotein
*191730___________ +1.30 +1.190.0060.0070.0442840836958338756.3234_non-histoneprotein10
192797___________ +1.06 +1.110.0370.0730.0521398814825154706.3726_putativehelicase
*192344___________ -13.65 -12.340.0000.0000.00041191430172333686.4207_DNA-dir
*192736___________ +2.24 +1.920.0000.0020.0012489555778477316.4692_transcriptionalregulator,partofNC2complex
*192423___________ +1.39 +1.390.0020.0050.0082250831362312966.5169_ureaact
*19314____________ +1.32 +1.020.0390.0190.4623073140573313126.5644_partofproteincomplexwithSin3pandStb1p
193423___________ +1.06 +1.070.0400.0370.1221382214587148016.6101_ORFMSV0
*19679____________ -1.20 -1.200.0110.0270.0232718822686226656.6572_hypotheticalprotein
*191901___________ +1.72 +1.430.0010.0010.0043740464428534096.7019_memberofcomplexthatactsatARS'stoinitiatereplication
*192081___________ +1.70 +1.480.0000.0010.0034209571734624536.7474_nuclearporemembraneglycoprotein
194620___________ -1.37 -1.490.0010.0060.0032424417659163126.7919_subunitoftheTIM22-complexinvolvedinmitochondrialbiogenesis
*197283___________ -2.55 -3.370.0000.0010.00015127259296449536.8364_hypotheticalprotein
*196833___________ +1.64 +1.880.0020.0090.0051398022911262826.8798_bumetanide-sensitiveNa-K-Clcotransportprotein,5-primeend
Caaf1____________ +1.11 +1.020.1660.0850.531119181317612203Caaf1__isoamyl
*195619___________ +1.38 +1.230.0000.0000.0042309431954283066.213__zincfin
*191649___________ +2.92 +3.200.0000.0010.0012131662194682966.825__alpha-g
*192519___________ +1.56 +1.460.0000.0010.0011770227651258046.1400_nuclearenvelopeprotein
193510___________ +1.08 +1.030.3230.2130.4581280913825132366.1943_hypotheticalgene
*193608___________ +1.55 +1.490.0010.0020.0021806627939269496.2464_actsinDNAmismatchrepair
*19796____________ +1.52 +1.400.0000.0010.0031728126252241146.2996_
*19139____________ +1.74 +1.490.0020.0060.0081730830076257076.3475_histoneacetyltransferase,componentoftheNuA4transcriptionalregulatorycomplex
*194257___________ +2.04 +1.670.0010.0010.0031763735914294336.3968_
19304____________ +1.21 +1.200.0070.0120.0241286715546153886.4441_
*191054___________ +1.96 +1.960.0000.0020.0011670032696328106.4935_
*196179___________ -2.29 -2.480.0020.0050.0053969417319160216.5400_hypotheticalprotein
193140___________ +1.11 +1.140.0190.0360.0391266614060144186.5877_
*195110___________ +2.29 +2.710.0000.0010.0012192350308594536.6339_
*196692___________ +3.34 +3.360.0000.0000.0002224774301746406.6801_alpha-1,2-mannosyltransferase
19359____________ -1.11 -1.140.0100.0510.0122027818239178346.7243_glutathioneS-transferase
195249___________ +1.29 +1.240.0010.0030.0051800223224223436.7693_conservedhypotheticalprotein
*197239___________ +1.46 +1.360.0010.0020.0021747225443237786.8139_regulationofG-proteinfunction
197411___________ +1.21 +1.260.0040.0160.0071583619213200256.8571_mitochondrialoxaloacetatetransportprotein
*197670___________ +2.21 +2.440.0000.0010.0011691037371411856.9017_
626______________ +1.30 +1.180.0060.0070.0491273116566150526.26___
*19231____________ +1.51 +1.340.0010.0020.0042223433538297036.518__
*19798____________ +1.35 +1.260.0000.0010.0022689836352339356.1138_transcriptioninitiationfactorTFIIFsmallsubunit|requiredforactincytoskeletonassemblyorfunction
193728___________ +1.19 +1.250.0180.0220.0561256615007156576.1687_
*193603___________ +1.50 +1.550.0010.0030.0032346335297364556.2224_conservedhypotheticalprotein
62744____________ +1.10 +1.080.0310.0300.1021247413673134496.2744_
*195561___________ +1.50 +1.520.0010.0020.0021758826352267446.3250_proteaseinvolvedina-factorprocessing
*193077___________ +1.38 +1.520.0020.0090.0033741451548567236.3742_
*194415___________ +1.26 +1.280.0010.0030.0032630633241337646.4224_
194654___________ +1.07 +1.070.0650.0490.2001266813569135996.4705_hypotheticalprotein
*192408___________ +1.23 +1.270.0020.0070.0051825222500231156.5185_conservedhypotheticalprotein
193981___________ +1.07 +1.050.5070.3130.6541423915190150176.5657_maltosepermease
192906___________ -1.01 +1.010.9440.8460.8182503824888252606.6116_hypotheticalprotein
*192765___________ +2.38 +2.730.0000.0010.0012215452807604346.6588_
191888___________ +1.12 +1.110.0110.0140.0491593217808176736.7032_uridineribohydrolase
*192069___________ +1.47 +1.480.0000.0010.0011921428173284756.7486_vacuolarmetaltransporter
*197006___________ +1.23 +1.260.0030.0060.0131611419837203336.7932_hypotheticalprotein
*197296___________ +2.29 +2.730.0000.0010.0002130348755581456.8377_conservedhypotheticalprotein
*196818___________ -1.23 -1.140.0050.0070.0242978024237262376.8813_RNAhelicase
Cacre9___________ -1.01 +1.020.6140.3530.960150121488715365Cacre9_
*196951___________ +1.77 +1.960.0000.0000.0002226239506435746.232__
*191534___________ +1.49 +1.510.0000.0010.0002255033687340716.838__
195753___________ +1.53 +1.410.0010.0020.0021643625147231716.1416_sugartransporter
*191917___________ +1.50 +1.700.0000.0010.0002512137658428286.1960_
191980___________ +1.18 +1.150.0090.0140.0291651419454189326.2480_glycerophosphoinositolpermease
*191250___________ +1.42 +1.350.0010.0030.0041837726048248096.3009_conservedhypotheticalprotein
*194268___________ +1.60 +1.800.0000.0020.0011986031844357336.3489_conservedhypotheticalprotein
*194774___________ -1.12 -1.020.0470.0240.4272853425591278616.3985_alternativeoxidase
*195515___________ -1.73 -1.840.0000.0010.0014216524361229666.4457_involvedincytochrome-creductaseassembly
195849___________ -1.08 -1.040.4360.2290.8203266830166313756.4951_transcriptionalregulator
196209___________ +1.09 +1.080.1070.1190.1512082622780225906.5414_
192253___________ +1.20 +1.090.1090.0470.8021521718212166346.5891_
192005___________ +1.03 +1.010.5070.2760.8581494415406151226.6356_
*196706___________ +1.91 +2.090.0000.0000.0002682451124560946.6815_GTPaseactivatingprotein
*194445___________ +1.55 -1.370.0010.0030.0092046031673148846.7258_hypotheticalprotein
195236___________ -1.23 -1.140.0090.0110.0482479820211217616.7706_cis-prenyltransferasehomologue
197254___________ +1.11 +1.100.0350.0410.0861802219989197966.8153_
197426___________ -1.16 -1.100.0360.0390.0952543621853230466.8586_subunitofN-oligosaccharyltransferasecomplex
*69033____________ +1.47 +1.710.0000.0010.0021604923590273836.9033_
193748___________ +1.21 +1.200.0120.0220.0301260515309151156.47___
191813___________ +1.28 +1.170.0060.0080.0311257816116146646.539__
*1917891__________ +1.69 +1.570.0010.0020.0021634527588255996.1158_NA
1910_____________ -1.08 -1.120.0170.0510.0241918017720171156.1706_cytochromep450
*193350___________ -1.42 -1.670.0050.0250.0084687033014281436.2238_mitochondrialribosomalprotein
192355___________ +1.10 +1.060.0810.0730.1691328414569140586.2760_
*192862___________ +1.24 +1.220.0120.0150.0482268828160276546.3269_
*194910___________ +1.50 +1.380.0010.0010.0106011790261829146.3757_hypotheticalprotein
*191287___________ +3.72 +3.370.0000.0000.000424181576871430086.4238_hypotheticalprotein
*19570____________ +1.76 +1.580.0000.0010.0012305340655364726.4721_
194287___________ -1.06 -1.060.1530.0950.3641697216050160816.5199_
196142___________ +1.08 +1.070.0570.0400.2131273213717136686.5672_conservedhypotheticalprotein
*192893___________ +1.57 +1.470.0010.0020.0023211150261471136.6129_partofmRNAspliceosomecomplex
194244___________ +1.17 +1.130.0040.0060.0181744320325196926.6601_
*191874___________ +1.33 +1.220.0030.0050.0151846524582224396.7046_serine/threonineproteinkinase
*192055___________ +1.67 +1.380.0000.0010.0012575842954354196.7499_
*197020___________ +1.29 +1.180.0040.0050.0284201654216497776.7946_carboxypeptidaseB-likeprocessingprotease|Killertoxinandalphafactorprecursorprocessing
*197310___________ -2.48 -2.350.0000.0000.00014506458509618186.8390_
*196805___________ -1.93 -2.110.0000.0000.0004397222749208126.8826_conservedhypotheticalprotein
42967____________ -1.01 +1.000.9210.9900.7201180811745118664.2967_
19384____________ +1.23 +1.070.0130.0100.1251615619805172396.247__
*193187___________ +1.50 +1.380.0000.0010.0023847257532531366.853__

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*192632___________ +1.84 +1.810.0000.0010.0012888153095523346.1437_RNAhelicaserequiredfor60Sribosomalsubunitassembly
*191950___________ -1.42 -1.460.0000.0020.0015342637629366206.1976_putativehydrolase
*193685___________ +2.39 +2.830.0010.0030.0021567237418442836.2494_
193226___________ +1.29 +1.170.0020.0030.0121317617047154756.3025_vacuolarproteinandhomologofNiemannPicktypeCprotein
195192___________ +1.29 +1.320.0030.0090.0071314616956173646.3503_conservedhypotheticalprotein
192938___________ -1.08 -1.120.3870.3430.3613822035469342596.4002_conservedhypotheticalprotein
*195530___________ +1.98 +2.010.0010.0020.0021711733891344106.4471_
192469___________ +1.01 +1.000.8750.6340.9602215622409221936.4966_ssDNAendonucleaseandrepairprotein
*196195___________ +1.72 +1.720.0000.0010.0002888249795495836.5429_ribonucleaseH
194927___________ +1.24 +1.260.0060.0100.0221487718510187126.5906_
196614___________ +1.06 -1.030.3940.2890.4442236223614216456.6375_
194105___________ +1.17 +1.240.0020.0080.0061838221587227396.6831_conservedhypotheticalprotein
*19906____________ +1.35 +1.280.0010.0030.0043194143268410316.7271_GDP-GTPexchangeproteinforRho1
196975___________ +1.09 +1.080.2660.3040.2301087541184351178856.7720_
*197269___________ -1.48 -1.770.0000.0030.0017828452777443326.8168_
197440___________ +1.10 +1.120.0120.0340.0201436815791160946.8600_ATP-dependentpermease
*195989___________ -1.76 -1.580.0000.0010.00210304858573651566.9047_
19376____________ +1.11 +1.020.0950.0520.3951548417122158356.64___
*192400___________ +1.49 +1.370.0030.0060.0131365620305187486.560__
19144____________ +1.22 +1.130.0070.0100.0311297115866147146.1176_ATPdependentRNAhelicaseandU5mRNAsplicingfactor
195576___________ +1.00 -1.010.6750.8850.4271743717473172646.1723_
62257____________ +1.21 +1.140.0090.0120.0371246815089142506.2257_
*191304___________ +1.44 +1.380.0030.0070.0111521421925210106.2776_rRNAprocessingexoribonucleasecomplexcomponent
*193612___________ -2.41 -2.170.0000.0000.00011982149693552866.3282_NADH:quinoneoxidoreductase|1,4-benzoquinonereductase
194366___________ +1.15 +1.090.0230.0200.1131277014652139046.3772_
*191835___________ +1.61 +1.630.0000.0010.0011650626538269366.4251_requiredforsomeformsofpolarizedgrowth,localizedtositesofpolarizedgrowth
*193347___________ -1.27 -1.250.0040.0110.0113687128959294766.4738_RNApolymeraseIIsubunit
194807___________ +1.11 +1.040.0980.0550.3691331214754138566.5213_mitochondrialinorganicpyrophosphatase
19593____________ +1.11 +1.080.0300.0320.0921231313613133086.5684_
195835___________ +1.09 +1.130.0290.0580.0441831220052206726.6142_
*194229___________ -1.61 -1.620.0010.0030.0043114519307191696.6616_polyphosphatephosphohydrolase
*19508____________ +2.98 +2.510.0000.0010.0021250937285314416.7063_multidrugresistancetransporter
193819___________ +1.13 +1.090.0130.0130.0681421316098155246.7514_hypotheticalprotein
*197033___________ +3.60 +3.090.0000.0000.0001700561256524716.7959_proteintyrosinephosphatase
*197322___________ +1.05 +1.290.0110.9800.00684806892521096926.8403_conservedhypotheticalprotein
196792___________ +1.18 +1.210.1390.3320.0961433216970173776.8839_ResistanttoRapamycinDeletion
41743____________ -1.02 -1.020.4570.2740.6401292712694126574.1743_
*1976_____________ +1.52 +1.580.0020.0080.0041550223621245086.268__
191279___________ -1.01 -1.020.6880.4160.9772771827402270816.874__CDP-diacylglycerolsynthase
*19258____________ +11.04 +14.570.0000.0000.000145301603402117456.1453_hypotheticalprotein
6199_____________ +1.19 +1.110.0070.0080.0431309315611145856.1990_
19107____________ +1.14 +1.130.0130.0140.0571282414596144406.2511_
191700___________ +1.07 +1.020.6140.3530.9621771918914180576.3041_ribosomalproteinS7A
*194703___________ +1.56 +1.430.0010.0030.0051693426453241856.3518_similartoricefar-redimpairedresponseprotein-like
*194744___________ +1.30 +1.230.0030.0040.0181331917266164206.4015_
*193190___________ +1.05 +1.160.0170.1520.0142817629702327386.4487_3rdgeneinHAL9repeatunit;weaksimtoHAL9factorinvolvedinsalttolerance;potentialFungalZn2Cys6Clusterdomain
193480___________ +1.00 -1.050.5590.7140.3561764317713167316.4979_ATPase(putative)|mitochondrialribosomesmallsubunitcomponent
196295___________ +1.02 -1.020.9130.6940.9861628916656160346.5445_subunitofthemitochondrialprocessingprotease
1928_____________ +1.04 +1.060.1030.0720.2601505115669158976.5922_mitochondrialthiaminepyrophosphatetransporter
191420___________ +1.04 +1.090.0820.3030.0551807318821196586.6389_conservedhypotheticalprotein
194091___________ +1.04 +1.050.1400.1800.1501646017071172336.6845_subunitofRNApolymeraseIIholoenzyme/mediatorcomplex
19893____________ +1.10 +1.020.0580.0250.7581297114226132626.7285_
196986___________ +1.08 +1.050.0940.0490.4351469015925153756.7732_putativeGTPaseactivatingprotein
192224___________ +1.07 +1.030.3150.2150.4331697618235174466.8183_
197452___________ +1.06 +1.100.0470.0650.0801464615571160666.8612_involvedinDNAreplication
195976___________ +1.20 +1.120.3460.1700.8411451517374162256.9061_hypotheticalprotein
69_______________ +1.29 +1.190.0130.0160.0511229915912146326.90___
19981____________ +1.17 +1.110.0130.0130.0751603218829177506.580__hypotheticalprotein
191818___________ +1.29 +1.290.0030.0060.0101265516360162696.1195_
*19449____________ +2.27 +2.070.0020.0040.0111504434138311566.1739_predictedphosphatidylsynthase
*196257___________ +2.89 +2.370.0000.0000.00038627111799916886.2273_
*194339___________ +1.51 +1.400.0020.0030.0081477422328207566.2796_vacuolarsortingprotein
194917___________ +1.39 +1.290.0030.0060.0141338118637172056.3296_hypotheticalprotein
195728___________ +1.23 +1.160.0050.0080.0251389417113160746.3792_
*192220___________ +33.15 +24.770.0000.0000.000261248660216472076.4265_hypotheticalprotein
*192107___________ +1.54 +1.200.0010.0010.0285190680078624706.4754_cholinephosphatecytidylyltransferase|phosphoethanolaminecytidylyltransferase
65228____________ +1.08 +1.080.0640.0560.1601258213579135286.5228_
192987___________ +1.02 -1.010.8980.7570.7792118421687209806.5702_hypotheticalmembraneprotein
*195823___________ -1.30 -1.470.0000.0010.0005311840951361136.6155_smallglutamine-richtetratricopeptiderepeatcontainingprotein|similaritytoproteinphosphatases
*195798___________ +1.14 +1.120.0140.0310.0282511428540282246.6632_DNAligaseIV
*19492____________ -1.06 -1.200.0390.3300.0259528890130793916.7079_5-aminoimidazole-4-carboxamideribonucleotide(AICAR)transformylase
*193836___________ +1.27 +1.190.0180.0120.1621781422698212296.7532_
*197047___________ +1.38 +1.370.0030.0070.0082528734875346246.7973_regulatesDNAbindingpropertiesofTATA-bindingprotein
197335___________ +1.17 +1.120.1150.2030.1063390639643380656.8416_20SproteasomesubunitY7
196780___________ +1.08 +1.070.0860.0840.1551436415449153576.8851_expressionofPAPSreductaseandsulfitereductase
42227____________ +1.01 +1.030.3500.2750.3851180711938121154.2227_
194512___________ +1.34 +1.260.0030.0050.0101276717136160806.281__
*193728___________ +1.48 +1.480.0060.0070.0311674124727247676.895__
192661___________ +1.31 +1.190.0010.0030.0081326617327158326.1466_transcriptionfactor
*191681___________ +3.20 +2.870.0000.0000.0002924993732839566.2003_
*191782___________ -1.41 -1.470.0000.0020.0015776540956394206.2529_conservedhypotheticalprotein
*194795___________ +2.99 +3.020.0010.0020.0021359240697410136.3054_
*19649____________ +1.65 +1.510.0020.0050.0091382022828208976.3532_
195097___________ +1.40 +1.410.0030.0070.0091433020083201486.4031_
*192838___________ +1.61 +1.850.0000.0000.0003556757124656266.4499_putativebeta-mannosidase
*194519___________ +1.10 +1.210.0150.2370.0113440437758416666.4992_mitochondrialRNAhelicase
*194678___________ +1.13 +1.080.0340.0270.1473194635990345916.5458_triacylglycerollipaseprecursor
*19204____________ +1.53 +1.420.0010.0020.0041570424066223126.5936_hypotheticalprotein
*191545___________ -1.46 -1.510.0000.0000.0004252229111282066.6403_mitochondrialribosomeprotein,smallsubunit
194079___________ +1.18 +1.180.0100.0230.0201672819765196906.6857_potentialSPFHdomain|possibleregulatorofcationconductance
673______________ +1.05 +1.060.0840.1030.1221197212539126816.7300_
196998___________ +1.22 +1.170.0080.0110.0291291415795151066.7744_glutathioneS-transferase
*19946____________ -2.10 -1.750.0000.0000.0008105738641463296.8195_adenylylsulfatekinase
*195389___________ +1.94 +1.930.0010.0030.0021532429804295866.8625_transcriptionfactor
195964___________ +1.08 +1.040.0910.0570.2991429415468148826.9073_ADP-ribosylationfactor|GTP-bindingprotein
*192479___________ +1.95 +1.620.0010.0030.0061287825065208086.108__
*19245____________ +1.33 +1.280.0020.0050.0091591521202203576.602__
192024___________ +1.34 +1.260.0040.0060.0161239316567156106.1212_
196079___________ +1.23 +1.100.0100.0090.0861291015903142416.1757_
*193772___________ -1.27 -1.190.0040.0060.0184335634005363916.2289_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*197561___________ +1.77 +1.950.0000.0010.0003141955672612116.2818_
*193651___________ -2.21 -1.900.0000.0000.0002546271153571338846.3309_
192557___________ +1.18 +1.120.0050.0070.0281481017494166306.3805_
193533___________ -1.03 -1.030.6910.6390.5251355913171131026.4279_
192371___________ +1.32 +1.810.2350.6410.1262988439409539516.4769_retrotransposongagprotein
193858___________ +1.25 +1.160.0060.0100.0211394717469162006.5247_
*192973___________ +1.34 +1.470.0010.0040.0012938639289432586.5716_conservedhypotheticalprotein
192488___________ +1.27 +1.250.0050.0160.0101508819227187956.6169_RNAhelicaseinvolvedinmaturationof18SrRNA
*195813___________ +2.32 +2.660.0000.0000.000475351102851265266.6647_
19477____________ -1.01 -1.050.5170.8420.2991615216009153996.7093_
*196559___________ +1.30 +1.360.0020.0070.0061609620880218866.7547_putativetranscriptioninitiationfactor
195023___________ +1.07 +1.120.0970.2740.0701250413428140356.7986_allantoatepermease
*197124___________ -1.67 -1.500.0020.0040.0081745101042941162656.8429_cytoskeletonstructure,endocytosis,cellfusionprotein
196766___________ +1.08 +1.110.0960.1510.1041413815294157016.8865_NucleolarProtein13
42533____________ +1.04 +1.050.6090.5050.5171442414950151224.2533_
192879___________ +1.28 +1.190.0090.0110.0391234615771147146.297__
*191296___________ +1.31 +1.310.0010.0030.0031609521140211426.922__pre-mRNAsplicingprotein
194954___________ +1.13 +1.070.0440.0330.1732163624526230676.1487_vacuolarATPaseV0domainsubunitc
194901___________ +1.25 +1.230.0030.0060.0101384017261170056.2024_trans-aconitatemethyltransferase
19806____________ +1.17 +1.140.0100.0150.0371987223154226456.2545_vacuolarH(+)-ATPase(subunitF)
193795___________ +1.22 +1.150.0040.0060.0231352616568155336.3068_aminoacidpermease
*19861____________ +1.48 +1.380.0000.0010.0022187132276301456.3553_bZIPprotein|transcriptionfactor
195813___________ -1.04 -1.080.1720.6570.0891189011462109746.4046_conservedhypotheticalprotein
*195645___________ -2.53 -2.190.0000.0000.00012466449337568836.4514_O-acetylhomoserinesulfhydrylase
*194215___________ +6.07 +6.410.0000.0000.000194931183451248746.5006_multicopperferro-O2-oxidoreductaseinvolvedinhigh-affinityironuptake
65471____________ +1.07 +1.070.0540.0390.1941223813144130416.5471_
195145___________ +1.13 +1.080.0340.0210.2291298214719139616.5953_
191560___________ -1.09 -1.080.1090.1200.1532060418819190596.6417_DNApolymerasedeltabindingprotein
196723___________ -1.19 -1.090.0100.0080.1162594521852237296.6872_hypotheticalprotein
*196927___________ +1.33 +1.440.0000.0010.0012583834412372766.7313_vesiculartransport
*193022___________ -1.88 -1.960.0010.0020.0023563818984181656.7759_mitochondrialribosomesmallsubunitcomponent
*19956____________ +1.93 +2.060.0000.0010.0011574830463324906.8210_
195404___________ +1.12 +1.110.0190.0220.0661442416192160796.8639_
195949___________ +1.10 +1.040.0990.0440.6781220013390127206.9087_
19141____________ +1.17 +1.170.0040.0080.0181230414423144066.127__hypotheticalprotein
6626_____________ +1.15 +1.160.0160.0350.0301276814640148166.626__
*192708___________ +1.64 +1.500.0010.0020.0032928548067437946.1233_highlyconservedhypotheticalprotein,involvedin35SrRNAprocessing
*192841___________ +2.05 +1.950.0020.0060.0061555831888303056.1775_phosphoglucomutase
*191538___________ +1.42 +1.370.0030.0060.0101444520464197416.2307_memberofthesyntaxinfamilyoft-SNAREs
194969___________ +1.14 +1.090.0090.0100.0461401215912153376.2837_
*19700____________ +1.69 +1.520.0000.0010.0013481458826530176.3324_
192642___________ -1.07 -1.080.0680.3260.0441176211014108676.3821_calmodulin
19301____________ +1.32 +1.180.0030.0060.0081603221138189716.4292_hypotheticalprotein,likelycellwalllocalizedandGPI-anchored
*195627___________ +1.58 +1.430.0000.0010.002845081331411205776.4786_simtornabindingprotein-putativepremrnasplicingfactor
*196552___________ +1.30 +1.210.0040.0050.0382487432451301836.5262_EssentialforRespirationandVegetativegrowth
*191261___________ +1.36 +1.170.0030.0040.0192185729725255776.5729_
195772___________ +1.25 +1.240.0070.0150.0181732221649214526.6186_actinoverexpressionresistant
*192956___________ -1.46 -1.660.0010.0030.0024510330958272136.6660_mitochondrialgenomemaintenanceprotein
191465___________ +1.27 +1.230.0030.0080.0091694421551208606.7108_arylalkylaminen-acetyltransferase
196575___________ +1.10 +1.080.1930.1390.3251550817128167216.7563_hypotheticalprotein
*195010___________ +1.57 +1.860.0010.0050.0031538224157286056.7999_dimethyladenosinetransferase
*197110___________ +1.40 +1.380.0010.0020.0022435534127336856.8443_tRNA-specificadenosinedeaminase
*196753___________ +1.24 +1.110.0150.0120.1143283840626363896.8878_conservedhypotheticalprotein
42762____________ +1.04 +1.040.1930.1440.3121227512804128184.2762_
*193599___________ +2.45 +2.350.0000.0010.0012225454528522736.316__
*19157____________ +1.23 +1.250.0130.0240.0304073350186508236.937__hypotheticalprotein
*193527___________ -6.88 -7.360.0000.0000.00067313397780914086.1503_
*193527___________ -9.18 -9.650.0000.0000.00016914001841531753196.2040_cytochromec1
*193787___________ +1.54 +1.510.0020.0040.0071760727135266106.2557_
*191214___________ +1.08 +1.210.0160.1490.0134336546842524356.3083_methionineaminopeptidase,isoform2
*192272___________ +1.62 +1.640.0020.0060.0061535824877251676.3570_
*193916___________ +1.69 +1.700.0010.0020.0021489225134252506.4060_hypotheticalprotein
196220___________ +1.33 +1.230.0040.0060.0181525620349187576.4532_conservedhypotheticalprotein
194200___________ +1.23 +1.100.0080.0080.0561477618161163196.5021_
192698___________ +1.09 +1.020.1230.0580.5841971321569200256.5486_conservedhypotheticalprotein
195132___________ +1.26 +1.190.0040.0070.0151429617970170126.5966_peroxisomalmembraneprotein
*191642___________ +1.31 +1.360.0030.0150.0061995226147271536.6430_nuclearmRNAbindingprotein
*196737___________ +1.12 +1.170.0160.0400.0273392238109397276.6886_hypotheticalprotein
*196941___________ -2.00 -2.340.0020.0100.004213620106830912466.7327_DiacylGlycerolAcyltransferase
*193035___________ +2.52 +2.530.0000.0010.0011919848319485566.7773_
*68224____________ +1.47 +1.510.0010.0030.0031701025054256056.8224_
*195418___________ -1.83 -1.790.0000.0000.0008220844802459786.8654_conservedhypotheticalprotein
195934___________ -1.27 -1.170.0040.0100.01211546910498606.9103_DNAtopoisomeraseIII
*192451___________ +1.12 +1.160.0250.0400.0511891121171219396.143__
*19999____________ -2.68 -2.920.0000.0000.0006845325561234316.649__glucoamylase
*192825___________ +1.23 +1.440.0010.0100.0013503843246504486.1251_
*19682____________ +1.37 +2.140.0000.0090.0002728037360584706.1794_
*192501___________ +1.65 +1.350.0020.0030.0101414623282190886.2325_
*191196___________ +1.53 +1.640.0000.0020.0012188433463358846.2850_
*193332___________ -1.68 -1.390.0000.0000.0027851246852564366.3339_hypotheticalprotein
*194878___________ +1.33 +1.380.0020.0090.0032798737195386316.3836_
*194479___________ +1.82 +2.000.0000.0030.0012616347524522656.4308_conservedhypotheticalprotein
*19276____________ +1.22 +1.280.0010.0060.0012653832360339936.4805_hypotheticalprotein
196539___________ -1.02 +1.010.6190.4290.6455281851563535376.5275_transcriptionalregulator
*191666___________ +1.57 +1.660.0000.0020.0011621025530268696.5741_hypotheticalprotein
*196591___________ +1.61 +1.770.0000.0010.0012081333536368816.6203_peroxisomalnudixhydrolaseactivetowardscoenzymeAanditsderivatives
*194527___________ +3.96 +2.640.0000.0000.001387681536321024446.6673_
191450___________ +1.03 +1.020.4570.2700.6591180212131120536.7123_hypotheticalprotein
*196588___________ +2.36 +2.620.0000.0000.0002685463300703856.7576_interactswithNap1,whichisinvolvedinhistoneassembly
194995___________ +1.01 +1.050.5900.4500.5501408714280148386.8014_hypotheticalprotein
197097___________ -1.05 +1.070.3120.3650.2476492262109696236.8456_RNAbindingprotein
*196739___________ +1.38 +1.700.0000.0020.0002224830699378316.8892_conservedhypotheticalproteinsimilartophosphomannomutases
42848f++3b_______ -1.05 -1.030.5210.6820.3291197611445116774.2848f
191356___________ +1.26 +1.180.0020.0030.0091510918984178656.331__
19236____________ +1.11 +1.090.0320.0370.0841967721811213636.955__ribosomalproteinL9B
191085___________ +1.18 +1.120.0100.0120.0521487617481166256.1518_
*19366____________ +1.22 +1.380.0010.0100.0024411053890607926.2056_3'-5'exonuclease
*193366___________ +1.02 +1.180.0160.3530.0101171541200031387306.2577_
*194565___________ -1.79 -1.380.0070.0070.07611939166867867836.3096_
192753___________ +1.10 +1.010.7310.4630.9262461027016248386.3585_hypotheticalprotein,zincfinger

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*192365___________ +1.53 +1.500.0000.0010.0021585724321238086.4075_DNA-directedDNApolymeraseepsilon,catalyticsubunitA
*1959_____________ +1.10 +1.370.0060.1350.0042970832611407976.4547_zincfingerproteinwithunknownfunction
*191970___________ +1.09 +1.160.0080.0400.0103175334544367126.5034_complementsS.cerevisiaevacuolebiogenesismutant,unpublished
*196312___________ -2.16 -1.880.0000.0000.000189344875451006666.5505_ribosomalproteinS3(rp13)(YS3)
*192041___________ -1.14 -1.110.0470.0340.1892977126096267806.5980_remodelsthestructureofchromatin
*191628___________ +1.20 +1.410.0000.0050.0003564042867502906.6445_
*195660___________ -1.95 -1.740.0000.0000.0004547923329261936.6900_peroxisomalbiogenesisprotein
196957___________ +1.14 +1.100.0120.0120.0671337815201146676.7343_hypotheticalprotein
193049___________ +1.03 -1.020.2870.1510.6311483815318146046.7786_putativeserine/threonineproteinkinase
193238___________ +1.06 +1.040.4000.2760.4851235313105128976.8238_hypotheticalprotein
*195431___________ +1.49 +2.080.0000.0010.0002008529946417446.8667_hypotheticalprotein
195920___________ -1.05 -1.010.2780.1270.9432278121746225816.9117_hypotheticalprotein
*191606___________ +1.78 +1.940.0030.0150.0051447725727281256.1____
*191217___________ +1.24 +1.150.0040.0060.0282364029306272326.669__conservedhypotheticalprotein
191907___________ +1.02 -1.040.5860.3430.8233253233299314296.1268_
193453___________ -1.10 -1.100.0440.1350.0431190810843108406.1813_
*193898___________ +1.61 +1.430.0010.0020.0052047032923292486.2341_memberofthesyntaxinfamilyoft-SNAREs
*19921____________ +1.88 +1.700.0000.0000.0013195459994544806.2867_hypotheticalprotein
192649___________ +1.20 +1.180.0080.0170.0191343716150157926.3355_
*19840____________ -1.53 -2.190.0000.0000.0003106112031851418496.3851_ribosomalproteinL21
193409___________ +1.28 +1.200.0050.0090.0181949525030233096.4322_
*19290____________ +1.71 +1.890.0020.0040.0051899132528358426.4818_
193001___________ +1.32 +1.230.0030.0060.0141612621226197716.5288_GTP-bindingproteinoftheRASsuperfamily
193574___________ +1.06 +1.050.1710.0870.5441238113174130256.5755_mitochondrialchaperoninoftheDnaJfamily
196605___________ +1.10 -1.080.2660.1240.8252691529477249926.6217_membraneproteinsimilartohumanandmouseglomerulosclerosisproteinMpv17
*194539___________ +2.41 +1.920.0000.0000.0003087574414593506.6685_putativerhoGDPdissociationinhibitor
196872___________ +1.18 +1.110.0070.0100.0311848221756204796.7136_similartoanthranilatesynthasecomponentII
*196045___________ -1.02 -1.340.0090.9810.0058951687822665966.7589_phosphatidylserinedecarboxylase
197130___________ -1.12 -1.210.0010.0290.0012141919197176786.8030_hypotheticalprotein
197083___________ +1.04 +1.060.1370.1020.2661570616354165746.8470_DefectiveinsisterChromatidCohesion|partofanalternativeRFCcomplex
197556___________ +1.05 +1.020.7620.5140.8372136722446218906.8904_hypotheticalprotein
43044____________ -1.02 -1.030.4670.9080.2561189411710115414.3044_
191086___________ +1.14 +1.120.0140.0220.0361280514552143296.349__
197451___________ +1.30 +1.170.0040.0060.0261275416567149636.974__
193820___________ -1.03 +1.050.4400.7700.2491184011508124306.1534_
*191386___________ +2.07 +1.820.0000.0010.0012188745332398326.2078_typeIImembraneproteinrequiredforvesiculartransportbetweentheendoplasmicreticulumandGolgicomplex|v-SNAREwithsimilaritytosynaptobrevins
*193775___________ +1.34 +1.200.0010.0020.0087340298054880916.2594_MAPkinasekinasekinase|ActivatorofPbs2p
191712___________ +1.20 +1.130.0140.0140.0741226814720138456.3115_
192783___________ +1.11 +1.120.0350.0490.0701436815923160246.3600_memberofthePir1p/Pir2p/Pir3pfamily
*191761___________ +1.25 +1.190.0030.0070.0102048425528243236.4088_oligosaccharyltransferaseepsilonsubunit
*195682___________ -1.19 -1.260.0060.0340.0091652301383701309176.4560_karyopherin-alphaorimportin
*195856___________ +1.49 +1.300.0050.0060.0341471621963190926.5048_hypotheticalprotein
196326___________ +1.05 +1.020.5410.3050.8313411435955348326.5519_hypotheticalprotein
196465___________ +1.17 +1.160.0250.0310.0681349415740156566.5994_conservedhypotheticalprotein
193445___________ +1.18 +1.090.3650.1860.7725032459303547546.6460_alpha-1,6-mannosyltransferase
*195674___________ -3.54 -3.530.0000.0000.00022488263437636416.6914_glycosyl-phosphatidylinositolprotein|similartoRBT5
194849___________ -1.03 -1.010.8640.8070.6782924428394289416.7362_nuclearproteininvolvedinubiquitin-dependentproteincatabolism
*193061___________ +1.09 +1.150.0270.0340.0702843831113327496.7798_mitochondrialinnermembraneprotease
193250___________ +1.01 +1.010.9170.7010.9861230012453124506.8250_splicingfactor
*195444___________ -1.42 -1.390.0010.0030.0033968028005285786.8680_innermembranetranslocasecomponent
*195908___________ +1.72 +1.820.0060.0140.0151737329828316316.9128_
*195293___________ +3.39 +4.070.0010.0030.0021264842929515086.35___
*19685____________ -2.32 -2.300.0010.0020.0024864621000211286.685__putativemitochondrialcarrierprotein
191986___________ -1.04 -1.000.5900.3650.7354416042341440906.1285_chorismatesynthase
193730___________ -1.06 -1.080.0600.1090.0731177811163108616.1829_
*192545___________ +1.43 +1.420.0000.0020.0015540879269785036.2354_derepressionoftelomericsilencing
193373___________ +1.14 +1.080.0160.0140.0891209013801130416.2887_RegulatorofIMe2expression
*192525___________ -2.75 -2.850.0000.0000.0003100761128231086116.3372_homo-isocitratedehydrogenase
192383___________ -1.16 -1.080.0980.0480.5144144535726382076.3865_Ku80componentofDNAend-joiningrepairpathway
*193394___________ +1.43 +1.380.0010.0030.0021821826057251206.4337_
191725___________ +1.17 +1.130.0100.0240.0191572018404177786.4834_
193705___________ +1.29 +1.340.0020.0060.0041722022169231166.5302_
196340___________ +1.20 +1.200.0060.0110.0191555618731186876.5769_RNApolymerasesubunit(commontopolymerasesI,IIandIII)
*196109___________ -1.65 -1.650.0040.0140.0082547741545021544206.6234_
*19809____________ +1.49 +1.700.0010.0060.0033090146040526496.6700_RNA-bindingnucleolarprotein
*196885___________ +1.16 +1.260.0020.0100.0033185037038401626.7149_CterminussimilartoproteinrequiredforpremioticDNAsynthesis
*196058___________ -1.29 -1.210.0010.0030.0078794868341728196.7602_glyoxalaseI
197148___________ +1.03 +1.030.1600.1480.2201223012646126346.8046_
*197070___________ +1.76 +2.040.0010.0040.0021612728366329706.8483_
197570___________ -1.01 +1.160.9290.9860.7364435043980513726.8918_zinc-fingertranscriptionfactoroftheZn(2)-Cys(6)binuclearclusterdomaintype
43108____________ +1.03 +1.020.4770.2570.8341240512748126154.3108_
*19563____________ +1.58 +1.670.0010.0040.0032139033831357126.367__conservedhypotheticalprotein
191356___________ +1.25 +1.150.3700.1980.6931504618739173786.1001_thiosulfatesulfurtransferase
*195534___________ +1.23 +1.380.0000.0030.0003052037504420716.1549_conservedhypotheticalprotein
19412____________ +1.01 +1.070.3770.8210.2012936629792315526.2095_involvedinco-translationalpathwayofproteintransport
*194132___________ +1.28 +1.380.0140.0540.019965581233321329896.2615_hypotheticalprotein
191155___________ +1.07 +1.040.1230.0980.2331473715713153056.3130_vacuolardiacylglycerolpyrophosphatephosphatase
*192436___________ +1.80 +1.440.0190.0130.1731689930459243736.3614_serinekinasethatphosphoryatesSRfamilysplicingfactors
*192594___________ +1.42 +1.270.0000.0010.0012968042189377166.4104_DNAdependentRNApolymeraseIsubunit
*195693___________ -2.13 -1.680.0000.0000.00012401958322737016.4575_
195611___________ +1.01 -1.011.0000.9910.9961624216372160986.5061_dihydroflavonol-4-reductases
192313___________ -1.17 -1.320.0060.0310.0092586322141195406.5537_conservedhypotheticalprotein
*196451___________ +1.48 +1.800.0180.1210.0173143646504565666.6008_polpolyprotein
*193432___________ +1.33 +1.320.0020.0040.0101635221812215836.6473_highlyconservedhypotheticalprotein
193117___________ +1.07 -1.040.4690.8980.2581805619405174206.6926_
194834___________ +1.08 +1.010.1620.0730.7361458015694147116.7377_hypotheticalprotein
196444___________ +1.03 +1.090.5110.7070.3153033431172329786.7810_RequiredforMeioticnuclearDivision
*193264___________ -1.28 -1.190.0190.0150.1194936038461415726.8264_cruciformcuttingendonuclease
*195457___________ +1.53 +1.780.0000.0020.0012278234857405346.8694_
*195893___________ -7.55 -6.670.0000.0000.0008172971082231224946.9144_componentofubiquinolcytochrome-creductasecomplex
197410___________ -1.01 +1.000.8160.5660.8971202211930120246.67___
*193599___________ +1.36 +1.260.0020.0040.0142123628865266986.703__
195754___________ +1.21 +1.140.0350.0310.1271276915455145006.1301_
193139___________ -1.11 -1.090.0450.0900.0581174810612107656.1850_
194636___________ +1.11 +1.110.0180.0210.0631399815480155766.2372_
19166____________ +1.05 +1.090.0850.1020.1241222412815133266.2902_
195052___________ +1.18 +1.120.0200.0160.1171479417402165836.3384_conservedhypotheticalprotein
193685___________ +1.07 +1.060.1010.0620.3211238813194131416.3881_PlatinumSensitivity
*195502___________ +1.58 +1.290.0010.0010.0042493239510322836.4350_hypotheticalprotein
191714___________ +1.05 +1.030.3130.1600.6981339614059138066.4847_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
193716___________ +1.10 +1.160.0240.0410.0461336314719155096.5314_hypotheticalprotein
196355___________ -1.08 -1.130.0380.2480.0271188811052105366.5784_involvedintheregulationofribosomebiosynthesis
*196094___________ +1.48 +1.350.0010.0030.0062079430677281136.6246_
*19825____________ +1.63 +1.780.0010.0030.0041924031361341586.6715_
*196901___________ +1.20 +1.140.0060.0080.0292444829405278636.7165_similartomRNAdecappingenzyme
*196071___________ +1.30 +1.070.0090.0050.3794277955489458246.7615_necessaryformitochondrialinheritance
*197160___________ +1.35 +1.360.0030.0060.0102257030530306086.8060_ankyrinrepeat-containingprotein
*197057___________ +1.61 +1.940.0010.0030.0031564525144303256.8496_glutamine-tRNAligase|glutamyltRNAsynthetase
*197586___________ +1.82 +1.850.0000.0010.0014717085625872486.8935_
6384_____________ +1.17 +1.150.0120.0130.0531263014742145636.384__
*193190___________ +1.20 +1.170.0030.0080.0104064748758473976.1023_
192928___________ -1.09 -1.140.0260.1200.0251228611257107716.1564_
191484___________ +1.27 +1.170.0060.0100.0201295616450151966.2108_hypotheticalprotein
194982___________ +1.35 +1.250.0010.0030.0041589821419198246.2629_triglyceridelipase-cholesterolesterase
63144____________ +1.10 +1.100.0310.0280.1161210513300133416.3144_
195536___________ +1.27 +1.180.0050.0080.0201263016058149566.3630_putativeamidase
*195550___________ +1.56 +1.620.0010.0040.0041640025665264876.4120_requiredformRNAdecay
194764___________ +1.15 +1.140.0080.0130.0271328815326150906.4591_componentofPab1-stimulatedpoly(A)ribonuclease
191240___________ +1.10 +1.080.0560.0700.0981397415369151106.5076_
192299___________ +1.15 +1.080.0320.0220.1871481217058160356.5551_ubiquitin-likeprotein
19723____________ +1.24 +1.150.0100.0100.0541498318637171946.6019_
*193675___________ +1.52 +1.500.0010.0010.0044604569857692786.6486_galactose-1-phosphateuridyltransferase
*193105___________ +4.40 +4.360.0000.0000.000288361268201255956.6940_cytochromeP450
196959___________ +1.04 +1.040.2470.2530.2451323613796137226.7390_firststepincommonpathwayformethionineandthreoninebiosynthesis|aspartatekinase(L-aspartate4-P-transferase)|L-aspartate4-P-transferase
196425___________ +1.07 +1.120.0180.0540.0261409615132157556.7826_
193277___________ +1.06 +1.030.1260.0730.3791312013890135786.8277_hypotheticalprotein
*195475___________ -1.24 -1.260.0030.0180.0044214133904335156.8711_hypotheticalprotein
195877___________ +1.04 +1.020.3370.1730.7221415814746144846.9160_alcoholacetyltransferase
*196018___________ +1.29 +1.510.0000.0040.0002439231463368016.91___
192654___________ +1.54 +1.340.0020.0040.0081361020999182286.721__putativetranscriptionregulator
*192166___________ +1.54 +1.440.0000.0010.0013369552031484646.1314_
191972___________ -1.08 -1.050.1650.2340.1501204311113114406.1863_conservedhyptheticalprotein
*192532___________ -1.34 -1.590.0000.0030.0014157131059261626.2386_prolyl-tRNAsynthetase,cytoplasmic
*193799___________ -1.22 -1.310.0070.0150.0204332735373330216.2917_reticulongenememberoftheRTNLA(reticulon-likeA)subfamily
195129___________ +1.36 +1.260.0020.0030.0111521920749192216.3402_conservedhypotheticalprotein
*19420____________ +9.71 +10.240.0000.0000.000175351703451794886.3895_
193503___________ +1.45 +1.320.0020.0040.0111316219051173746.4363_hypotheticalprotein
*193000___________ +1.55 +1.670.0030.0070.0111589524571264886.4865_
196166___________ +1.10 +1.020.4940.3190.5992782530554285036.5327_alpha/betahydrolase
*194899___________ -2.78 -3.380.0000.0010.0006056021763179066.5798_
*19400____________ +1.49 +1.270.0000.0010.0032962444199377026.6264_hypotheticalprotein
19516____________ -1.00 -1.080.4870.9310.2692738927352253346.6728_flippaseforMan5GlcNac2-PP-DolintheERmembrane
196913___________ +1.19 +1.270.0100.0210.0251386816532176056.7178_
196532___________ +1.13 +1.070.0450.0270.2711390615651149356.7628_mitochondrialFADcarrier
197175___________ +1.14 +1.120.0140.0180.0501591718095178416.8074_
*197347___________ +1.64 +1.700.0010.0050.0012240036800380586.8507_ubiquitin-conjugatingenzyme
*197599___________ +1.17 +1.300.0050.0470.0062825832941367626.8947_conservedhypotheticalprotein
194742___________ +1.19 +1.210.0070.0120.0221476217510178996.403__hypotheticalprotein
191434___________ +1.47 +1.380.0010.0030.0061425820949196156.1038_DNApolymeraseIIcomplexcomponent
191806___________ +1.27 +1.200.0050.0080.0251684021336201546.1580_
*191045___________ +1.59 +1.480.0020.0050.0051476523459219266.2126_
*191344___________ +3.93 +2.900.0000.0010.0011287650612373986.2644_hypotheticalprotein
*194309___________ +3.69 +3.980.0000.0000.00026456976581052406.3162_
194185___________ +1.33 +1.250.0030.0050.0151263416847158186.3642_weaksimilaritytoprotein-tyrosine-phosphatase
*19745____________ +2.50 +2.910.0000.0000.000572221432461665366.4134_vacuolememebraneproteinrequiredforvacuoleinheritance
194304___________ +1.23 +1.130.0060.0090.0281471318030166646.4608_
*196011___________ +2.05 +2.080.0000.0000.0002860058630595656.5091_transcriptionregulatoryprotein
*192667___________ +1.58 +1.790.0000.0020.0013257751529583056.5567_
196274___________ +1.14 +1.080.0470.0460.1181264614398137106.6033_hypotheticalprotein
*19430____________ +1.42 +1.330.0030.0100.0081701624190227106.6499_GTP-bindingproteinoftherabfamily
*195180___________ -1.75 -1.780.0000.0010.0012067581184681164226.6956_regulationofredoxhomeostasis
*193994___________ -1.23 -1.360.0050.0110.0164730038375348096.7407_oligosaccharyltransferasegammasubunit
*196411___________ +1.20 +1.280.0080.0190.0181648719733210856.7842_
195303___________ +1.05 -1.000.1490.0630.9721503915767149906.8292_hypotheticalprotein
*197475___________ +1.38 +1.320.0090.0150.0301559321570205616.8728_
*19675____________ -1.72 -1.930.0000.0010.000182879106412948036.132__
192681___________ +1.18 +1.140.0230.0260.0711331315648152426.741__
*191614___________ +2.50 +2.650.0000.0010.0011853546330491426.1335_
193198___________ -1.14 -1.090.0800.1790.0731181310380108696.1881_amatinglocusoxysterol-bindingprotein
194820___________ +1.08 +1.170.0610.2880.0412460226626286816.2399_conservedhypotheticalprotein
*193378___________ +2.09 +1.890.0010.0020.0061263626469239326.2935_
195201___________ -1.06 -1.060.1740.4780.1031748316465164436.3417_mitochondrialribosomalsmallsubunitprotein
195217___________ +1.08 +1.080.0890.0730.1971395615018150286.3908_acyl-CoAthioesterase
*191796___________ +1.28 +1.130.0040.0050.0352356730078266856.4375_similartoglyceratedehydrogenases
191318___________ +1.22 +1.250.0090.0160.0251584219325198806.4880_hypotheticalprotein
191581___________ +1.03 +1.020.3050.1750.5481249212882128036.5339_hypotheticalprotein
19983____________ +1.10 +1.100.0660.0640.1421252013771137346.5815_
*19388____________ +2.77 +2.510.0000.0000.0003469096061870536.6276_CCR4/NOTtranscriptionregulationcomplexassociatedfactor,ATPbinding(ABC)domain
19532____________ +1.02 -1.170.0850.9880.0404987951090425376.6743_
*193295___________ +1.32 +1.310.0020.0040.0071973225992257666.7190_hypotheticalprotein
196518___________ +1.06 +1.080.0530.0790.0811232213020133106.7641_
*197187___________ -1.35 -1.690.0020.0100.0044351432167256826.8087_mitochondrialacidicmatrixprotein
197361___________ +1.08 +1.180.0470.0910.0601283813886151316.8521_tRNA-splicingendonucleasesubunit
*197612___________ +1.70 +1.570.0000.0000.00161881105066972476.8960_cytochromecmethyltransferase
19621____________ +1.26 +1.170.0030.0040.0201265816000148166.418__
191437___________ +1.24 +1.180.0060.0150.0131931323884227416.1055_
193559___________ -1.08 -1.080.0700.1180.0841172110848108196.1603_
191077___________ +1.47 +1.200.0030.0030.0281716625313206536.2144_
194958___________ +1.13 +1.130.0080.0130.0271365515397154836.2658_proteininvolvedincellwallbiogenesisandarchitecture
19270____________ +1.15 +1.100.0120.0150.0481269214564139246.3179_hypotheticalprotein
194744___________ +1.27 +1.180.0050.0070.0241846423501217386.3656_myotubularin-relateddualspecificityphosphatase
*191691___________ +34.88 +38.910.0000.0000.000196856865847658596.4148_conservedhypotheticalprotein
*191191___________ -1.45 -1.470.0020.0060.0047183649654488706.4628_responsibleforER-associateddegradation(ERAD)ofnumerousER-residentproteins
*196127___________ -1.39 -1.480.0010.0040.0036105844029411266.5109_
*192326___________ +1.63 +1.520.0030.0050.0112105234224320686.5581_
194945___________ +1.25 +1.200.0060.0070.0321427117867171756.6046_
19445____________ -1.01 -1.030.7660.9410.5132382023675231126.6514_hypotheticalprotein
*195167___________ -1.52 -1.520.0000.0010.0013527023170232476.6969_mitochondrialtranslationinitiationfactor2
*194006___________ -1.52 -1.450.0010.0030.0033464622820238956.7419_ketopantoatereductase
*196393___________ +1.93 +2.010.0000.0020.0011777534311356476.7860_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*195316___________ +1.88 +1.810.0010.0020.0041549429098280966.8305_simtoNADHdehydrogenasesubunit5
*197488___________ +2.87 +2.650.0000.0010.0001974256665522196.8740_componentofU3snoRNP;pre-18SrRNAprocessing
196400___________ +1.15 +1.120.0160.0310.0311464016852163986.165__
192435___________ +1.25 +1.170.0050.0090.0201253115631146096.760__
*191741___________ +1.63 +1.660.0010.0040.0041404922948232846.1352_firstenzymeinsynthesisofdityrosineinthesporewall,convertingL-tyrosinetoN-formyl-L-tyrosine
192825___________ -1.10 -1.110.0210.0580.0301161010534104986.1899_conservedhypotheticalprotein
193947___________ +1.21 +1.170.0220.0290.0601621519642189286.2414_Zn-fingerprotein,transcriptionalregulator
191198___________ +1.00 -1.010.7870.5210.9581211612161119936.2947_conservedhypotheticalprotein
*191826___________ +1.47 +1.300.0020.0030.0191466921520190386.3433_mitochondrialoutermembraneproteininvolvedinmitochondrialshape
192516___________ +1.09 +1.070.0710.0510.2162452126836263286.3921_proteindisulfideisomerase
*193207___________ +1.45 +1.410.0020.0050.0091525522077215226.4392_G1cyclin
*194785___________ -1.12 -1.100.0180.0310.0424588441028415476.4895_proteinserine/threoninephosphatase2c
*191401___________ +1.94 +2.130.0000.0010.0002376746144506776.5354_putativeregulatoryprotein
*196377___________ -1.21 -1.180.0060.0100.0233271727057276286.5829_carboxymethyltransferaseforproteinphosphatase2A
*195081___________ +1.61 +1.720.0000.0010.0003650158784629456.6296_
*19544____________ -1.68 -1.450.0000.0010.00310220060708704786.6756_RNasePsubunit
*193308___________ -1.35 -1.410.0010.0030.0043879228667275196.7203_SIN3bindingprotein
196506___________ +1.25 +1.310.0060.0130.0151488518610194676.7655_
197200___________ +1.08 +1.040.1300.0740.3971281213790132726.8100_hypotheticalprotein
68533____________ +1.07 +1.020.4270.4290.3411486815921151996.8533_
*197625___________ -1.25 -1.170.0150.0150.0763187725513273146.8973_KRE1proteinprecursor
194728___________ -1.03 +1.010.9610.9880.8061211611768122826.439__
*191590___________ +1.69 +1.640.0010.0030.0021521425735250246.1068_hypotheticalprotein
194903___________ +1.17 +1.130.0170.0180.0731283914995145726.1620_N-acetylglucosaminylphosphatidylinositolde-N-acetylase
191268___________ +1.19 +1.080.0190.0150.1211285215321139246.2161_
*193166___________ +1.90 +1.770.0000.0010.0011979037568349976.2674_
194121___________ +1.10 +1.050.0830.0520.2951279414113133856.3192_peroxisomalacyl-CoAthioesterase
*192396___________ +1.58 +1.460.0010.0010.0031582624927230626.3677_alcoholdehydrogenase
*191375___________ -2.93 -2.910.0000.0010.0019519732517327276.4161_alpha-isopropylmalatesynthase
193553___________ +1.11 +1.030.1680.1200.3091979521977203346.4648_ribosomelargesubunitassembly
*196231___________ -1.26 -1.300.0350.0530.0653172225144244816.5125_
191942___________ +1.08 +1.100.0110.0360.0182044822062224176.5597_MDRtransporter
194164___________ +1.16 +1.150.0160.0270.0371257814646144606.6059_
*196632___________ +1.23 +1.310.0010.0100.0022244427595294696.6530_
195155___________ +1.07 +1.110.0340.1140.0341821519418202626.6982_
194019___________ +1.09 +1.070.2050.1600.3032486527193265746.7432_hypotheticalprotein
194579___________ +1.04 +1.060.0790.1940.0682245623378238256.7878_ER-Golgitransportvesicleprotein
*195328___________ +1.29 +1.290.0010.0030.0061760722713227456.8319_
*197501___________ +2.15 +2.260.0000.0000.0003002864412678216.8753_nucleosomeassemblyproteinI
*194970___________ +3.54 +4.310.0000.0010.0011846265445796336.180__
*192013___________ +1.21 +1.050.0170.0090.3232067725102216626.779__
1976_____________ +1.14 +1.130.0100.0140.0351394915952158126.1368_
193934___________ -1.07 -1.080.3000.6230.1691209711326111756.1912_
*194950___________ +1.61 +1.790.0020.0080.0051452523331260626.2433_ankyrinrepeat-containingprotein
19191____________ +1.13 +1.080.0170.0160.0841835020678199026.2964_proteinkinasethatinteractswithCdc31p
191163___________ -1.01 -1.040.5280.8830.3041850818383178226.3446_
*195299___________ +1.57 +2.010.0010.0060.0031822628688366746.3935_cellwallstructureorbiosynthesis
*193195___________ -1.84 -2.030.0010.0050.0013070516727151346.4405_
195728___________ +1.00 -1.000.4400.2440.7241214012170121166.4907_cytochromeP-450
*192133___________ +1.35 +1.360.0040.0070.0171579721377214496.5367_secretedlipase
*193877___________ +2.45 +3.340.0010.0040.0021450535519484186.5848_
*194394___________ +1.18 +1.070.0250.0160.2092275026761243396.6313_hypotheticalprotein
196662___________ -1.06 -1.080.0800.2210.0641521414348141016.6771_conservedhypotheticalprotein
*193322___________ +1.49 +1.330.0020.0030.0212568738318341466.7217_
*195274___________ +1.73 +1.390.0000.0000.0013230855921449836.7668_conservedhypotheticalprotein
197212___________ +1.17 +1.150.0220.0270.0651224014276140546.8112_AP-2complexsubunit,beta2-adaptin
*197385___________ +2.58 +3.500.0000.0020.0011500838760524786.8545_zincfingerprotein|spindlepoisonsensitivityrelatedprotein
197642___________ +1.17 +1.140.0240.0250.0801325915535150726.8988_
*19693____________ +1.36 +1.370.0010.0050.0041672722731229686.457__hypotheticalprotein
*191674___________ +2.12 +1.880.0000.0000.0002371250321445226.1083_ubiquitinligase(cullin)ofSCFinvolvedincellcyclecontrol
61636____________ -1.11 -1.070.0380.0550.0721179910661110256.1636_
191139___________ +1.03 +1.010.7060.4340.9777467076606752286.2177_
193159___________ +1.36 +1.330.0040.0090.0141248316956166146.2690_possiblesnoRNAbindingprotein
194072___________ +1.10 +1.070.0700.0500.2201221913396130626.3205_
19687____________ +1.17 +1.140.0050.0090.0191563218356177896.3692_hypotheticalprotein
195483___________ -1.06 -1.120.1370.2650.1082856026867255376.4177_similartoE.colielongationfactor-typeGTP-bindingproteinLepA
*64663____________ +1.98 +2.050.0010.0030.0021817035946373216.4663_
193907___________ +1.03 +1.080.1730.1370.2721237012762133706.5141_hypotheticalprotein
*191847___________ +1.72 +1.720.0010.0040.0051728229648296936.5615_
194179___________ +1.00 +1.000.5340.3170.7331194811995119906.6073_hypotheticalprotein
*196645___________ +2.88 +2.830.0000.0000.000709222041912009716.6542_highmobilitygroup-likeprotein
*196846___________ +1.70 +1.610.0010.0040.00361203103755986946.6995_cyclin-dependentkinase
*194032___________ +1.44 +1.370.0020.0040.0061849626700254226.7445_
*194593___________ +2.94 +3.050.0000.0020.0021762051802537466.7892_rhoGTPaseactivator
*195345___________ +1.35 +1.320.0010.0020.0024007454050528456.8334_requiredwithRAD23forduplicationofthespindlepolebody,ubiquitin-likeprotein
*197514___________ -6.80 -6.350.0000.0000.00025368383728173994306.8766_phosphoenolpyruvatecarboxykinase
194607___________ +1.12 +1.120.0320.0270.1341393315674156196.198__
191915___________ +1.27 +1.220.0050.0080.0171259215954153876.803__
*191301___________ +1.57 +1.460.0010.0030.0051763227750257556.1386_hypotheticalprotein
193358___________ -1.08 -1.100.0500.1780.0421170510848106076.1927_succinate-CoAligase
*192289___________ +1.43 +1.410.0000.0020.0015297675565744606.2449_actin-relatedprotein
191106___________ +1.10 +1.150.0280.0550.0461280614100146996.2982_hypotheticalprotein
*192917___________ -1.77 -1.700.0000.0000.00114693382870863156.3460_
*19911____________ +1.92 +2.040.0000.0000.0004301282762878066.3951_
*195585___________ +1.58 +1.520.0010.0040.0041508523849229836.4427_secretedaspartylproteinase5
*64921____________ +1.71 +1.800.0000.0010.0003194854735573976.4921_
*192150___________ -2.98 -3.140.0000.0000.00021281271523677826.5384_putativeelectroncarrier
*193127___________ +1.57 +1.670.0010.0040.0041767127672294846.5864_zincfingerprotein
*194382___________ +1.34 +1.300.0000.0010.0025943679682774136.6325_Golgi-to-ERvesiclecoatcomponent
196678___________ +1.09 +1.110.0310.0450.0661183212925130786.6786_
*19346____________ -1.89 -1.820.0010.0040.0036441334155353056.7230_alaninetransaminase
*195260___________ +1.80 +2.160.0020.0080.0051434825780309866.7681_
*197225___________ +1.25 +1.470.0010.0130.0012020625262297086.8126_
*197397___________ +1.22 +1.450.0030.0150.0041896923155274396.8557_zincfingerprotein
197657___________ -1.08 +1.050.1590.1820.1783091228653324156.9005_RNasePandRNaseMRPsubunit
191573___________ -1.05 -1.020.6400.3730.9898835684329867246.477__
*191092___________ +1.36 +1.380.0020.0100.0042668436263369536.1100_dol-p-mandependentalpha(1-3)mannosyltransferase
191601___________ -1.10 +1.060.4780.2700.7391223091107901301196.1651_
193719___________ +1.35 +1.220.0050.0070.0321255216945152916.2194_hypotheticalprotein
193630___________ +1.13 +1.090.0250.0280.0771273814413138936.2709_nucleolarproteinrequiredforefficientprocessingofpre-rRNAatsiteA2

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
191030___________ +1.22 +1.170.0110.0170.0321411317250165216.3221_peptidyl-prolylcis-transisomerases(PPIase)|FK506-rapamycinbindingprotein
196484___________ +1.17 +1.040.0200.0120.2511332615588138776.3711_
*194499___________ -1.40 -1.180.0040.0030.1013537925184299756.4191_mitochondrialcarrierproteinthatisrequiredforrespiration
192579___________ +1.47 +1.540.0020.0040.0061437421133220866.4679_
19218____________ +1.09 +1.050.0450.0230.4161280813967134156.5155_hypotheticalprotein
*19328____________ +1.41 +1.510.0010.0040.0032303032488347006.5630_nitrogenpermeaseregulator
192178___________ -1.22 -1.080.0180.0170.0932294218762212866.6085_RNAsplicingproteinandmemberofthemitochondrialcarrierfamily(MCF)
19666____________ +1.37 +1.340.0020.0040.0061444819813193506.6559_
196858___________ -1.04 +1.010.6610.4670.6632026019555205426.7007_conservedhypotheticalprotein
*192095___________ +1.12 +1.340.0020.0230.00281905920251095186.7460_X-Proaminopeptidase
194607___________ +1.04 +1.000.4120.2630.5471361314183136316.7906_conservedhypotheticalprotein
195363___________ -1.06 -1.060.4590.7700.2631419713390134566.8352_glycosyl-transferaseinvolvedinosmotolerance
*197529___________ +1.76 +2.000.0000.0010.0014540679971909746.8780_
1939_____________ +1.07 +1.060.0940.0860.1771249113370132046.3____hypotheticalprotein
19751____________ -1.09 -1.160.0680.0570.1732201420128189756.500__hypotheticalprotein
*193959___________ +1.40 +1.290.0240.0510.0392505635048322526.1118_
19776____________ +1.01 +1.030.3890.7570.2151209312179124396.1672_sporulationproteininvolvedinsisterchromatidcohesion
192821___________ +1.17 +1.090.4740.3170.5532482628938271086.2209_putativeNADH-ubiquinoneoxidoreductase
192710___________ +1.15 +1.120.1230.1430.1541943622444217656.2726_regulatorysubunitforproteinser/thrphosphataseGlc7p
191730___________ +1.44 +1.620.0020.0140.0041427620494231536.3235_
192798___________ -1.05 -1.060.1810.2070.1901580315103148866.3727_putativehelicase
*192344___________ -9.33 -10.380.0000.0000.00024788826564238876.4208_hypotheticalprotein
*192737___________ -1.42 -1.330.0220.0230.0805881241422441636.4693_kinase
192422___________ +1.07 +1.020.8040.9670.5532153823134219786.5172_
*19313____________ +1.11 +1.190.0210.1170.0201730219236205266.5645_
193422___________ +1.05 +1.070.1360.2460.1131247413049134066.6104_
19681____________ +1.22 +1.490.1490.1760.1681428217354212546.6574_
191901___________ +1.13 +1.110.0070.0140.0181282214429142626.7021_
*192081___________ +1.46 +1.230.0030.0050.0171818126461224166.7475_
194621___________ +1.06 +1.110.0210.0440.0371240213178137246.7920_weaksimilaritytopigtubulin-tyrosineligase
*197284___________ -2.35 -2.180.0000.0020.0013802016175174376.8365_conservedhypotheticalprotein
*196832___________ +1.46 +1.770.0010.0080.0021333019453236276.8799_bumetanide-sensitiveNa-K-Clcotransportprotein,3-primeend
ALS1_____________ -1.03 -1.060.1750.3320.126123211191511677ALS1___
*191785___________ +2.72 +2.340.0000.0000.0002449666538574416.214__
*191650___________ -2.95 -3.420.0000.0000.00015358752079449006.826__mitochondrialoutermembraneimportreceptorsubunit
*192520___________ -2.55 -2.890.0000.0010.0017120027871246296.1401_mitochondrialribosomalsmallsubunitprotein
193512___________ +1.13 +1.090.0180.0320.0401340915135146386.1946_
*193609___________ +1.48 +2.030.0010.0070.0011409820887286386.2465_partofsmall(ribosomal)subunit(SSU)processosome(containsU3snoRNA)|U3snoRNPprotein
*19797____________ +2.67 +3.160.0000.0000.0002541067818802596.2997_
19138____________ +1.16 +1.170.0090.0140.0301268514711147986.3476_integralmembraneproteinrequiredforefficientmating
*194255___________ +1.58 +1.620.0170.0720.0204217466559683076.3969_protoplast-secreted
*19305____________ -1.99 -2.060.0010.0020.0025356026958259396.4443_multidrugresistance-typetransporter
*192842___________ +3.48 +4.030.0000.0000.000357421245141440436.4936_transcriptionalrepressorsimilartozincfingerDal80
196180___________ -1.24 -1.070.1350.0940.2954422535717414316.5401_conservedhypotheticalprotein
*193141___________ +1.62 +2.060.0010.0040.0011649426740339436.5878_
*195107___________ +1.28 +1.520.0340.1520.0292130027232323746.6342_
196693___________ +1.18 +1.180.0180.0440.0291574618549186016.6802_conservedhypotheticalprotein
*194433___________ +1.19 +1.550.0080.0450.0112041924349315806.7245_
195248___________ +1.23 +1.180.3580.3520.3122956036424349986.7694_hypotheticalprotein
*197239___________ +1.58 +1.570.0120.0500.0173791660092594286.8140_
*197412___________ +1.58 +2.100.0000.0040.0011695126860356566.8572_zincfingerproteininvolvedinbudsiteselection
*197672___________ -1.29 -1.160.0170.0120.1563796929520326536.9020_conservedhypotheticalprotein
*194497___________ +1.41 +1.260.0040.0050.0201608622743202346.30___
*193626___________ +1.79 +1.930.0000.0010.0001914034253369536.522__
19799____________ +1.45 +1.300.0020.0040.0071350419557175736.1139_
*193732___________ +1.83 +1.960.0000.0000.0003434862718673956.1689_
*193603___________ +1.62 +1.970.0020.0100.0044704876315926316.2225_
193968___________ +1.19 +1.060.0190.0110.2641287215368136156.2745_hypotheticalprotein
195559___________ +1.01 +1.020.7260.4610.8991855018822188706.3251_
*193077___________ +1.24 +1.260.0030.0090.0072093626053264256.3744_
194414___________ -1.01 +1.050.3350.5900.1992106120886220946.4225_
*194655___________ +1.21 +1.220.0350.0900.0412832834398345656.4706_oligopeptidetransporterprotein
*192407___________ -1.66 -1.830.0000.0020.0017749746739422976.5186_aspartyl-tRNAsynthetase
193982___________ +1.02 -1.050.2720.9020.1351904419487180996.5658_alpha-glucosidasemaltase
192905___________ +1.14 +1.100.0310.0440.0651451916540159156.6117_hypotheticalprotein
*192763___________ +1.66 +1.600.0010.0030.0021489524761238616.6589_hypotheticalprotein
*191887___________ +1.65 +1.950.0000.0010.0003026850088590006.7033_similaritytotriacylglycerollipases
192068___________ -1.03 -1.030.5330.7560.3242040019900198676.7487_hypotheticalprotein
197007___________ +1.06 +1.020.2530.1230.6981323914084135046.7933_hypotheticalprotein
*197297___________ -1.10 +1.250.0440.2040.0346887462540860946.8378_cystathioninegamma-synthase
*196817___________ +1.62 +1.760.0020.0070.0071805129251318006.8814_zincfingertranscriptionfactorinvolvedinpleiotropicdrugresistance
Caecm39__________ +1.04 -1.020.3670.1890.752116141205511352Caecm39
*192347___________ +1.20 +1.260.0030.0150.0042547830490319896.233__
191533___________ +1.43 +1.350.0050.0060.0311348419262182186.839__conservedhypotheticalprotein
195752___________ +1.38 +1.210.0060.0080.0321293017833156286.1417_
*191917___________ +1.66 +1.700.0010.0030.0022256337413382496.1961_
*191979___________ +2.12 +2.430.0000.0000.000534231130981295566.2481_glycerophosphoinositolpermease
*191249___________ +1.27 +1.300.0020.0050.0052198527852285266.3010_phosphoribosyl-5-amino-1-phosphoribosyl-4-imidazolecarboxiamideisomerase
194266___________ +1.18 +1.120.0160.0180.0621268414985142516.3490_
194346___________ +1.22 +1.160.0150.0150.0741263715418146556.3988_
*195516___________ +1.31 +1.530.0010.0060.0023116340974476676.4458_signalrecognitionparticleprotein
*195850___________ +1.35 +1.790.0020.0620.00261952838981111956.4952_conservedhypotheticalprotein
196208___________ +1.36 +1.350.0030.0060.0121513220624203906.5417_
192251___________ +1.16 +1.130.0330.0360.0911252514473141066.5895_adenineaminohydrolase|adeninedeaminase
*192003___________ -1.33 -1.460.0050.0170.0088031860536551036.6357_cholinepermease
196708___________ +1.29 +1.140.0140.0140.0771278816460145416.6817_nicotinamidase|pyrazinamidase
*194446___________ +1.10 +1.280.0060.0580.0063028033381386666.7259_putativepermease
195235___________ -1.04 -1.070.1360.2100.1271777617089166876.7707_hypotheticalprotein
197255___________ -1.01 +1.070.9180.8200.7716626865556706356.8155_DNA-directedRNApolymerasessmallsubunit
*197427___________ +1.50 +1.680.0000.0010.0003186147768535036.8587_conservedhypotheticalmembraneprotein
*196003___________ +2.87 +2.660.0000.0000.0002084059776553616.9034_conservedhypotheticalprotein
193748___________ +1.16 +1.210.0030.0140.0061304715083157736.46___hypotheticalprotein
191813___________ +1.35 +1.350.3750.8020.2014221456797568276.540__
191346___________ +1.17 +1.140.0170.0840.0181478017258169186.1159_hyphallyregulatedcellwallprotein
199______________ +1.16 +1.100.2810.1280.9841377116008151436.1707_
191389___________ +1.02 -1.070.7560.8020.5291933619741180266.2241_
*194216___________ -5.82 -4.830.0000.0010.00137223264007770766.2761_heatshockprotein
192862___________ +1.20 +1.080.1950.2170.2021956923469212136.3268_GTPcyclohydrolaseII,firststepinriboflavinbiosynthesis
194912___________ +1.35 +1.280.0030.0100.0081671022498213736.3759_conservedhypotheticalprotein
191286___________ -1.07 -1.020.2160.1280.4461306812238127616.4239_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*19575____________ +1.41 +1.620.0030.0180.0041729924397281026.4722_
194286___________ +1.15 +1.290.0030.0330.0041359415699174696.5200_hypotheticalprotein
196141___________ -1.00 -1.150.0780.3540.0491918919113166296.5673_high-affinityhexose(glucose)transporter
192892___________ -1.00 -1.010.6610.8020.4281204711992118816.6130_hypotheticalprotein
194243___________ +1.06 +1.140.0470.1170.0501393814782158746.6602_
*191873___________ -1.32 -1.460.0090.0170.0242932122146201186.7047_
192054___________ -1.03 -1.110.2030.2780.1732043219912183746.7501_hypotheticalzincfingerprotein
197021___________ +1.26 -1.150.2910.5690.1701418881783911232096.7947_glycogenphosphorylase
197311___________ +1.04 +1.140.0790.4910.0431494215499170916.8392_hypotheticalprotein
196804___________ -1.01 +1.070.0870.6820.0431225212183131206.8827_signalrecognitionparticle68
Cakre99__________ -1.03 -1.060.2250.4180.148119841165811350Cakre99
194063___________ +1.28 +1.110.0070.0060.1171260316113140306.248__
194975___________ +1.23 +1.170.0180.0330.0361581219377184266.856__
*192633___________ +1.66 +1.660.0080.0410.0113685561220610006.1438_quinatepermease
*191952___________ -1.52 -1.660.0020.0070.0054660230583279956.1977_
*193683___________ +1.45 +1.610.0010.0080.0021405220368226926.2496_
193227___________ +1.11 +1.280.0080.0570.0091319414630168636.3026_potentialirontransporter
193967___________ +1.15 +1.140.6740.7620.4511283501478721469116.3504_6-phosphofructokinase,alphasubunit
192939___________ +1.04 +1.100.2190.2650.1981305613569143576.4003_conservedhypotheticalprotein
193175___________ -1.12 -1.140.1470.0990.3213875634493341166.4472_
192468___________ +1.20 +1.170.0140.0280.0301373416469160896.4967_trans-aconitatemethyltransferase1
196194___________ +1.17 +1.250.0030.0250.0051514417729189416.5430_hypotheticalprotein
*194928___________ +1.85 +2.010.0000.0010.0012234641431448456.5908_GDP/GTPexchangefactorforSec4p
191409___________ +1.29 +1.320.0020.0110.0051512319459200276.6379_
194104___________ +1.04 +1.080.1310.4060.0801287913358138546.6832_diguanylatecyclase/phosphodiesterasedomain-containingprotein
*19905____________ -1.24 -1.310.0260.0380.0596663153590510026.7272_aminoacidtransporter
196975___________ +1.28 +1.210.6680.8850.421932561191171132566.7721_ribosomalproteinS0A
197270___________ -1.13 -1.020.6300.4080.7216960461868683116.8170_hypotheticalprotein
197441___________ +1.11 +1.230.0070.1530.0061685418780207926.8601_conservedhypotheticalprotein
195989___________ +1.03 +1.030.6040.5530.4711378414223141876.9049_
19377____________ +1.20 +1.140.0100.0090.0831282115358145526.66___
192401___________ +1.64 +1.530.0010.0020.0021292021225197226.561__anchorproteinthatmediatesattachmentofautophagosomestomicrotubules
19145____________ -1.00 -1.030.8560.7660.6891200211967116626.1177_RNApolymeraseIIfourthlargestsubunit
195576___________ +1.18 +1.130.0100.0130.0441399816511157846.1724_panthotenatekinase,3-primeend
196044___________ +1.29 +1.090.0040.0040.0501357617492148176.2258_
191153___________ -1.10 -1.100.1320.0880.3074460940455404166.2779_
193613___________ +1.30 +1.220.0040.0060.0161310717035159956.3284_
194365___________ +1.12 +1.080.0220.0170.1361481116519159746.3773_
191834___________ +1.29 +1.210.0030.0060.0151532619704185656.4252_nuclearporecomplexsubunit
193348___________ +1.00 -1.000.7700.8410.5341683216836168016.4739_
*194808___________ +1.57 +1.560.0010.0030.0032395037651372436.5214_nucleoporin|nucleartransport
19593____________ +1.16 +1.100.0180.0170.0891637619048180116.5685_
195835___________ +1.04 +1.050.1440.1690.1652237023207234366.6143_involvedinpre-rRNAprocessingandribosomeassembly
194228___________ -1.07 -1.040.6300.9970.3815383250287515156.6617_conservedhypotheticalprotein
19506____________ +1.01 +1.150.0870.8560.0423120431584358796.7064_
193821___________ +1.13 +1.070.0360.0340.1111441416323153636.7516_hypotheticalprotein
*197034___________ +1.49 +1.550.0020.0090.0062057430675319836.7960_hypotheticalprotein
197323___________ +1.06 +1.080.0990.3090.0682440825874264076.8404_corticosteroid-bindingprotein
*196791___________ +3.06 +3.110.0000.0010.0012504276542778086.8840_histoneH3
41841____________ +1.12 +1.140.0120.0300.0231444416201164874.1841_
*19493____________ +1.50 +1.520.0030.0080.0075945889058905336.269__
*193680___________ +1.75 +1.370.0020.0040.0161492726131205086.875__septininvolvedincytokinesis
19259____________ +1.37 +1.180.0060.0070.0421319618122155506.1454_hypotheticalprotein
19251____________ +1.02 -1.010.6370.9730.3872570426335254616.1991_conservedhypotheticalprotein
*194123___________ +1.80 +1.450.0030.0050.0131429925725207786.2512_playsaroleintranscriptionalelongation
191701___________ +1.12 +1.040.0470.0430.1311326814802138556.3042_ribose-5-phosphateketol-isomerase
194702___________ +1.26 +1.140.0060.0070.0311272416020144596.3519_hypotheticalprotein
*194746___________ +1.27 +1.380.0040.0160.0082252028695310216.4016_JumonjiInteractingProtein
*193192___________ +1.12 +1.150.0470.0380.1583037934026350626.4488_
193478___________ -1.02 +1.390.0700.9050.0333954038700549736.4981_nucleolarproteinrequiredfor60Sribosomesubunitgenesis
196296___________ +1.13 +1.070.2160.1420.3831276814457136436.5446_involvedinglucosederepression
1929_____________ +1.03 +1.050.2020.1370.3571267313029133656.5923_hypotheticalprotein
*191421___________ +1.59 +1.530.0000.0000.0003341653165509826.6390_ureidoglycolatehydrolase
*194090___________ -1.80 -1.760.0000.0010.0014732826257269616.6846_conservedhypotheticalmembraneprotein
*19891____________ +2.25 +2.310.0010.0040.0051543334732356326.7287_
196987___________ +1.09 +1.190.3780.6190.2265091255401605406.7733_dynaminGTPaseinvolvedinreceptor-mediatedendocytosisandmitochondrialorganization
19935____________ +1.08 +1.000.1860.0810.9771229513248123436.8184_hypotheticalprotein
*197453___________ +1.64 +1.420.0010.0020.0031910331327271436.8613_hypotheticalprotein
195975___________ +1.03 +1.030.4020.2160.7281226112646125886.9062_zincfingertranscriptionfactor
195606___________ +1.10 +1.060.5250.2830.9711218813443129646.94___
195770___________ +1.10 +1.350.0020.0420.0021279214093173196.582__
191123___________ +1.16 +1.080.0480.0490.1161216014087131676.1198_hypotheticalprotein
193150___________ +1.01 +1.070.1670.7650.0821239712560132706.1740_similartoplantdihydroflavonol4-reductase
196257___________ +1.04 +1.050.1390.1590.1661248813032131506.2271_
194340___________ +1.02 +1.020.5960.5160.4891257812837127746.2797_hypotheticalprotein
194918___________ +1.03 +1.020.3170.1790.5721228312637125096.3297_conservedhypotheticalprotein
195725___________ +1.04 +1.050.3540.3850.2831218312612128076.3794_hypotheticalprotein
192222___________ +1.08 +1.100.3800.6310.2262140223202235986.4267_caseinkinaseI
192106___________ -1.01 -1.010.6760.4050.9821458614460144086.4755_conservedhypotheticalmembraneprotein
194149___________ -1.04 -1.040.4690.3540.4751552214932149546.5230_hypotheticalprotein
192986___________ -1.00 +1.020.6220.8920.3791215812145123986.5703_conservedhypotheticalprotein
195821___________ -1.02 -1.020.7550.9280.5021181411552115756.6156_
195799___________ +1.11 +1.060.5720.6890.3733276936521347156.6633_conservedhypotheticalprotein
*19491____________ +1.17 +1.110.0310.0620.0462025823751224666.7080_involvedinproteinimportintoER
193836___________ -1.05 -1.020.2210.1080.6571251811973122516.7531_conservedhypotheticalprotein
195035___________ -1.02 +1.010.6730.5860.5391273012528128816.7974_proteininvolvedinhistonegenetranscriptionregulation
197336___________ -1.03 -1.040.3140.3500.2591180011498113466.8417_similartoMFSeffluxtransporter
196779___________ -1.04 -1.050.0870.1680.0841272312197120786.8852_gamma-glutamylphosphatereductase,Prolinebiosyntheticenzyme
42327____________ -1.02 -1.020.7720.7240.5841195911770116884.2327_
191871___________ +1.22 +1.130.0040.0050.0321242615182140516.284__
*193728___________ +1.51 +1.470.0020.0080.0051840427853270516.896__
194793___________ +1.29 +1.290.0040.0160.0071377117742178136.1469_conservedhypotheticalprotein
194476___________ +1.25 +1.230.0030.0110.0071257915737154596.2004_
191783___________ +1.32 +1.310.0020.0070.0041276316884166816.2530_
*194796___________ +1.43 +1.400.0040.0080.0141814625960253906.3055_bindstoeIF-4E,themRNAcap-bindingprotein
19646____________ +1.12 -1.050.7140.5460.6503334037477317556.3535_
195098___________ +1.11 +1.120.0590.1050.0741285514300143586.4034_
195632___________ -1.12 -1.030.4740.2520.8579189582053892476.4501_glycophospholipid-anchoredsurfaceglycoprotein
194518___________ +1.13 +1.100.0920.1660.0921572617712173616.4993_serine/threonineproteinkinase
194677___________ +1.12 +1.080.0230.0310.0601258214036135966.5459_weaksimilaritytoprobablecyclinG1interactingprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
19206____________ +1.04 +1.030.3820.2240.5971236812846127256.5937_
*191546___________ -1.59 -1.740.0010.0040.0022918518405167326.6404_conservedhypotheticalprotein
*196709___________ -1.63 -1.830.0030.0070.0076028436943329166.6858_similartoepoxidehydrolase
19876____________ +1.01 -1.130.3090.3200.2724390644235389766.7301_hypotheticalprotein
196999___________ +1.04 +1.020.3980.2370.5971227312747124936.7745_taurinecatabolismdioxygenase
19947____________ -1.15 -1.190.0070.0310.0101854116057156326.8196_mitochondrialribosomalprotein
*195390___________ +1.58 +1.700.0000.0030.0011868129550317316.8626_hypotheticalprotein
195963___________ +1.09 +1.100.0890.1100.1231348214698148176.9074_conservedhypotheticalprotein
*194873___________ +5.70 +5.090.0000.0000.00018021102780917836.113__
194068___________ +1.28 +1.230.0030.0050.0151244415875152476.604__
191350___________ +1.30 +1.140.0050.0060.0311251216209142026.1214_
194704___________ +1.06 +1.020.1370.0620.6812357525060240666.1758_
193773___________ +1.26 +1.190.0040.0070.0131265815899150206.2290_weaksimilaritytodouble-strandedribonuclease
*19409____________ +1.33 +1.430.0000.0010.0014704262780673806.2819_conservedhypotheticalprotein
*193649___________ +1.43 +1.220.0050.0050.0501914227277233196.3312_
192558___________ +1.19 +1.140.0110.0140.0401275815227146086.3807_hypotheticalprotein
*193534___________ +1.38 +1.330.0010.0020.0024558363093605586.4280_GTP-bindingproteinoftherhofamily
192374___________ +1.22 +1.320.0830.2490.0621885423050249496.4772_retrotransposongagprotein
*193859___________ -1.27 -1.250.0180.0250.0515049439677403166.5249_hypotheticaloxidoreductase
*192972___________ +2.02 +1.890.0000.0010.0012212944728417586.5717_nucleotidephosphodiesterase
*192489___________ +1.33 +1.320.0000.0020.0013108641434410246.6170_ranbindingprotein|homologofimportin-beta
*192967___________ -1.64 -1.680.0000.0010.0017968148499473456.6649_translationinitiationfactoreIF3,p39subunit
191478___________ -1.08 -1.050.2080.3620.1472388122079228056.7095_oligosaccharyltransferasesubunit|integralERmmebranesubunitrequiredforproteinglycosylation
196561___________ +1.02 +1.020.5390.3110.7792182522243221726.7548_
*195022___________ +1.14 +1.110.0200.0240.0642821132276314436.7987_manganeseiontransporter
*197123___________ -1.39 -1.300.0450.0380.1481523501097761172206.8430_hypotheticalprotein
*196763___________ +1.33 +1.260.0120.0300.0231474841960351859126.8867_
42581____________ +1.04 +1.030.4340.2900.5281175212260120594.2581_
192537___________ +1.24 +1.110.0390.0230.2771309116216145166.298__hypotheticalprotein
191298___________ +1.30 +1.200.0060.0070.0351360317749163856.923__nuclearporecomplexsubunit
194955___________ +1.37 +1.290.0020.0040.0101519220742196656.1488_sporulation-specificprotein2precursor
62027____________ +1.28 +1.160.1810.2630.1551275416332148446.2027_
19805____________ +1.07 +1.070.1060.0740.2631789019146190576.2546_conservedhypotheticalprotein
193796___________ +1.12 +1.140.0560.0430.1811279514303145266.3069_ribonucleaseIII
19857____________ +1.39 +1.180.0040.0050.0301384719295163836.3555_
193929___________ +1.03 -1.000.7830.7140.6062045621108204486.4047_
*195646___________ +1.07 +1.060.0430.0310.1792146422953227776.4515_conservedhypotheticalprotein
194214___________ +1.28 +1.280.0040.0080.0151308216769167846.5007_hypotheticalprotein
*193743___________ +1.11 +1.170.0400.2860.0273287936367385556.5473_hypotheticalprotein
195144___________ +1.07 +1.050.1120.1100.1761558416667164176.5954_
*191560___________ -1.36 -1.220.0020.0030.0264786035250392876.6418_
*196724___________ -4.08 -4.780.0000.0010.0018484920806177636.6873_mitochondrialfumaratehydratase,5-primeend
*196928___________ -1.36 -1.080.0470.0200.766131153966281216046.7314_secretedaspartylproteinase9
193023___________ +1.23 +1.220.0150.0270.0361369016810166446.7761_
*19962____________ +1.78 +2.010.0000.0020.0013167656356637026.8211_hypotheticalprotein
*195406___________ +1.41 +1.480.0070.0140.0191396019655207016.8642_phosphatase
*195949___________ +1.15 +1.140.0040.0130.0092293826443260666.9088_
19141____________ +1.09 +1.140.0130.0710.0141239213471141236.128__
195203___________ +1.08 +1.110.0550.0940.0731180812780131056.627__
193168___________ +1.15 +1.040.7260.8310.4882421827850252686.1236_componentof19Sproteasomeregulatoryparticle
*61776____________ +1.47 +1.370.0090.0190.0221761525936242116.1776_
193848___________ +1.04 +1.070.1630.2590.1371223912723131266.2310_
194969___________ +1.02 +1.000.7570.4860.9651217912441121856.2836_
19701____________ +1.02 +1.030.8980.8520.7131234012576127186.3325_ferricreductase
192641___________ +1.05 +1.060.1430.2300.1271194412483126976.3822_centractin-actin-relatedproteinofthedynactincomplex
19300____________ -1.04 -1.040.2330.1580.3811410913593136276.4293_mitochondrialD-lactatedehydrogenase
195628___________ +1.00 +1.070.2670.6890.1421233712367131776.4787_mitochondrialdicarboxylatetransportprotein
196551___________ +1.02 +1.020.8620.6560.8231279913075130016.5263_SNAREproteinwithaC-terminalmembraneanchor
*191263___________ +1.20 +1.260.0110.0620.0131668220096210106.5730_ferricreductase
195771___________ +1.03 +1.020.6690.4170.8261242012845126226.6187_PAB1bindingprotein
*192954___________ -1.34 -1.970.0040.0210.0056238846565316216.6661_
*191464___________ +1.21 +1.200.0180.0310.0401519418449182266.7109_genefamilyofunknownfunction
196577___________ -1.01 -1.020.7140.5630.6281186411714116386.7564_
195009___________ -1.02 +1.000.6610.5040.6051715416841171846.8000_Kelch-repeatcontainingprotein
197109___________ -1.05 -1.060.1110.1410.1351452813804136926.8444_ankyrinrepeatprotein
196752___________ -1.06 -1.070.1790.2140.1811230511592115496.8879_mitochondrialribosomesmallsubunitcomponent
42768f++2________ -1.03 -1.040.4260.5040.3011177511446113134.2768f
*193599___________ +1.30 +1.290.0060.0090.0232324230264300566.317__
*19156____________ +1.33 +1.220.0180.0670.0232497433100303976.938__hypotheticalprotein
*191133___________ +1.84 +1.890.0010.0040.0011802733180340896.1504_
193528___________ +1.34 +1.280.0020.0080.0061490419951190576.2041_conservedhypotheticalprotein
193788___________ +1.11 +1.150.0090.0320.0141241213764142276.2559_
191212___________ +1.10 +1.110.1920.4540.1181832020085203056.3085_requiredforinositolmetabolism
*192270___________ +2.23 +2.160.0000.0030.0012542256743548366.3571_manganesetransporter
*193915___________ +1.85 +1.960.0010.0040.0021587229430311106.4061_
196222___________ +1.12 +1.110.0280.0660.0401385315531153236.4534_sporulation-defective
*194199___________ +1.45 +1.760.0030.0130.0061371419864241706.5022_
192699___________ -1.15 -1.350.0550.1150.0639589783429712206.5488_
195131___________ +1.10 +1.100.0370.0560.0651233713581135686.5967_
191639___________ +1.14 +1.100.0250.0560.0381253114348138026.6432_
*195647___________ +1.34 +1.290.0280.1260.0272567734331332206.6887_
196942___________ +1.10 +1.110.4950.5520.3493490838515388836.7328_Or(ISS)nrecognitioncomplex
193037___________ +1.10 +1.240.2740.7740.1411180521297301467156.7774_3'-endRNA-processingcomplexcomponent
19976____________ +1.25 +1.310.0090.0170.0231227415300160876.8226_
*195419___________ -4.22 -4.670.0000.0000.00035534484199760876.8655_F1F0-ATPasesubunit
195933___________ -1.03 -1.060.1340.2810.1011210411721114306.9104_hypotheticalprotein
19625____________ +1.39 +1.200.0060.0050.0611254617394150836.144__
19999____________ +1.17 +1.120.0080.0090.0451263414720140986.650__
191841___________ +1.22 +1.120.0050.0080.0221246015144139066.1253_hypotheticalprotein
*19680____________ -2.06 -1.970.0000.0000.0007657937202389156.1796_
192503___________ +1.22 +1.140.0060.0090.0311296815856147696.2326_hypotheticalprotein
*19461____________ +2.35 +2.490.0020.0060.0061438633812358726.2853_hypotheticalprotein
*193333___________ -1.82 -1.730.0000.0010.00314814881556857096.3340_polyadenylatedRNAbindingprotein
194878___________ +1.34 +1.250.0650.0760.1143394245530425106.3838_
*194478___________ -1.40 -1.200.0010.0020.0103539025202294476.4309_aspartyl-tRNAsynthetase
*19277____________ +1.13 +1.200.0030.0350.0042868432512345486.4806_thiamin-phosphatepyrophosphorylaseandhydroxyethylthiazolekinase
*196538___________ +1.53 +1.540.0030.0100.0073954660319609956.5276_
*191667___________ +1.16 +1.250.0060.0380.0073375439243422106.5742_DNA-dependentATPaseofthenucleotideexcisionrepairfactor4complex
196592___________ -1.22 -1.030.1040.0450.7724222534496409366.6204_membranetransporter
*194528___________ +1.31 +1.310.0030.0090.0082336030562305426.6674_conservedhypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*191449___________ -3.83 -3.580.0000.0010.0015625914707157226.7124_cyanamidehydratase(byhomology)
*196033___________ +1.34 +1.310.0020.0040.0052232730012293366.7577_
194993___________ +1.04 +1.040.2590.1940.3512088021751217746.8015_vesicularfusionprotein
197096___________ -1.10 +1.050.6460.5650.519105311960341101386.8457_conservedhypotheticalprotein
*196738___________ +1.49 +1.570.0020.0070.0071534122843240726.8893_vanadateresistanceprotein
43029____________ -1.00 -1.030.6990.8320.4591172611697113404.3029_
*191357___________ +6.49 +7.890.0000.0000.000455392955383592666.332__
*19238____________ -1.40 -1.260.0110.0110.0719791969854776536.956__
*195067___________ +1.51 +1.410.0020.0070.0041929629112271946.1520_conservedhypotheticalprotein
*19367____________ +2.25 +1.870.0010.0020.0031648237133308746.2057_
*193367___________ +1.40 +1.500.0000.0020.0012656637185397736.2578_conservedhypotheticalprotein
194566___________ +1.14 +1.070.0330.0210.2381420416149152306.3098_membraneprotein
192754___________ -1.13 -1.170.0520.0690.0902358420872201566.3586_translocaseofthemitochondrialinnermembrane
192364___________ +1.26 +1.240.0030.0060.0101777322425220306.4076_tetrahydrofolatesynthase
*1958_____________ +1.58 +1.680.0010.0050.0033603457021606256.4548_ribosomalRNAprocessing3'-5'exonuclease
191969___________ -1.03 -1.030.4430.2990.5272282722066220716.5035_cellwallmannoproteininvolvedincellstressresponse
196313___________ +1.19 +1.210.0040.0160.0061937023033234146.5506_similaritytomannosyltransferases
192042___________ +1.01 +1.000.9910.9730.9082252822746225906.5981_mitochondrialGTPaseinvolvedintranslation
*191626___________ -1.55 -1.470.0000.0000.0013846624834261096.6446_deoxyhypusinesynthase
*195661___________ -1.62 -1.490.0000.0010.0028480252474570046.6901_conservedhypotheticalprotein
*194864___________ +1.92 +1.770.0010.0020.0021861435816330176.7347_
*193050___________ +1.27 +1.270.0030.0070.0092101426600267196.7787_GTPaseactivatingprotein
193239___________ +1.11 +1.070.1610.0950.4001241613745132716.8239_chromosometransmission
*195432___________ +1.37 +1.420.0010.0060.0022983240950423766.8668_tRNA2-phosphotransferase
195919___________ +1.18 +1.170.0040.0070.0141513217920177266.9118_conservedhypotheticalprotein
1940_____________ +1.19 +1.130.0350.0350.1071292415369146116.5____
191219___________ -1.04 -1.060.3250.5560.1981161011196109686.671__
*191910___________ -1.15 -1.360.0010.0140.0024444338791326926.1269_putativeoxydoreductase
*193455___________ +1.41 +1.330.0010.0030.0041967327721261896.1814_mitochondrialtransmembranetransporter
193897___________ +1.44 +1.390.0380.0260.1861560322516216616.2342_hypotheticalprotein
191768___________ +1.17 +1.110.0150.0150.0701644819284183326.2869_conservedhypotheticalprotein
192646___________ -1.10 -1.080.0310.0800.0381167810580108186.3357_
19841____________ +1.43 +1.190.0050.0060.0411358419449161526.3852_
193407___________ +1.05 +1.040.5180.3420.6031931120365200306.4324_DNArepairproteinandATPase
*19610____________ +5.72 +6.420.0000.0000.000242971389081558966.4820_
*193000___________ +1.84 +1.800.0010.0030.0021963836037353786.5289_
*193573___________ -1.28 -1.630.0010.0110.0014653936257284666.5756_peroxisomalassemblyprotein|AAAATPase
196606___________ +1.08 +1.060.0860.0630.2321304914087137966.6218_conservedhypotheticalprotein
*194540___________ +4.98 +4.600.0000.0000.000372201853161710836.6686_E2ubiquitin-conjugatingenzyme
*196873___________ -1.44 -2.200.0020.0300.0025198323601122364826.7137_ribosomalproteinS8E
*196046___________ +2.07 +1.690.0000.0010.0022312847784389996.7590_subunitofanaphase-promotingcomplexandubiquitinligase
*197131___________ -3.88 -4.730.0000.0000.00012347631812260986.8031_conservedhypotheticalprotein
197082___________ +1.01 -1.020.9660.9020.8451943619636190026.8471_mitochondrialcarrierprotein
197557___________ +1.39 +1.230.0070.0110.0311305818199160306.8905_hypotheticalprotein
43073f--2b_______ -1.01 -1.000.9990.9660.9941158411420115664.3073f
*191087___________ +2.42 +2.030.0010.0020.0041732241839352076.351__
191351___________ +1.44 +1.240.0110.0140.0421403420159173686.978__hypotheticalprotein
192867___________ +1.15 +1.080.0230.0160.1541519217472164056.1535_involvedinGolgiretentionandvacuolarsorting
191384___________ +1.45 +1.410.0020.0060.0071708224734240286.2079_
*193774___________ +1.26 +1.210.0080.0110.0383613645387437316.2595_
191711___________ +1.15 +1.070.0250.0170.1911426416418152836.3116_requiredforcytoskeletalorganization
192784___________ +1.11 +1.010.1180.0540.6311567617340158936.3601_hypotheticalprotein
*191760___________ +1.20 +1.300.0140.0450.0204717256576614536.4089_smallmonomericGTPaseinvolvedinhyphaedifferentiationandthetransmissionofcAMPsignals
*195683___________ -2.29 -1.770.0000.0000.00114191061975803176.4561_conservedhypotheticalmembraneprotein
195857___________ +1.01 +1.030.9960.9720.9423504435286359916.5049_hypotheticalprotein
*196327___________ +1.14 +1.320.0010.0060.0011128181283601488896.5520_involvedinnonallelicheterokaryonincompatibility
*196462___________ -1.07 -1.150.0240.2950.0163091628917269216.5997_conservedhypotheticalprotein|conservedhypotheticaltransmembraneprotein
193444___________ +1.01 +1.000.8360.5810.9611757917727176106.6461_putativeMFS-MDRtransporter
*195675___________ +1.30 +1.270.0050.0090.0174743361899601186.6915_SNF2familyDNA-dependentATPase
*194848___________ +1.24 +1.180.0060.0150.0122305228519272156.7363_antiviralproteinwithtetratricopeptiderepeats
*193062___________ +1.53 +1.460.0000.0010.0012074631683303106.7799_conservedhypotheticalprotein
193251___________ -1.04 -1.060.2710.4400.1811712016528161776.8251_structuralprotein
*195445___________ +1.71 +1.480.0000.0010.0043253055630482556.8681_GTP-aseactivatingproteinforArf
195906___________ +1.05 +1.110.3470.7680.1865106553778567746.9131_phosphoribosylamino-imidazole-carboxylase|purinebiosynthesis
*195294___________ +1.54 +1.400.0020.0050.0081287619772180896.36___
194860___________ +1.31 +1.140.0140.0110.1261459019183166996.687__hypotheticalprotein
196222___________ +1.31 +1.320.0010.0040.0041475219265194336.1288_
*193727___________ +1.73 +1.640.0010.0020.0031667928813273826.1832_
192547___________ -1.03 -1.070.0780.1250.0922261421931211916.2356_
193371___________ +1.20 +1.090.0150.0130.0961216414631132616.2889_conservedhypotheticalprotein
192525___________ +1.11 +1.120.6620.4190.7894491849915504476.3371_
192382___________ +1.66 +1.470.0010.0020.0041439123958211546.3866_isoleucine-tRNAligase
192203___________ +1.21 +1.130.0100.0100.0551284415484145716.4338_hypotheticalprotein
*191724___________ +1.38 +1.130.0060.0060.0661602622150181806.4836_hypotheticalprotein
193706___________ +1.23 +1.250.0320.0460.0641468518052183556.5303_
196341___________ +1.02 +1.100.4380.7880.2452677827300294786.5770_secondstepintheriboflavinbiosynthesispathway|5-amino-6-(5-phosphoribosylamino)uracilreductase
*196109___________ -1.64 -1.800.0000.0030.00111821571981655686.6235_
19810____________ +1.18 +1.170.0070.0100.0341508017804176946.6701_C4zincfingerDNA-bindingproteinoflowsequencespecificityinvitro|probable119kDaDNA/RNAhelicasefamilymember
*196886___________ +1.54 +1.690.0000.0010.0002540039235428076.7150_conservedcoiledcoilsprotein
*196059___________ -3.91 -3.000.0000.0000.000309970792131034876.7603_glutaredoxin
197148___________ -1.00 +1.030.7840.8060.5621453514469149826.8047_
*197068___________ +1.39 +1.480.0020.0060.0051691823451249796.8485_metal-bindingtranscriptionfactor
*197571___________ +2.03 +2.090.0000.0000.0002762856116576516.8919_Ubiquitin-conjugatingenzyme
43108____________ +1.14 +1.090.0190.0200.0781235614036134454.3108_
19564____________ +1.00 -1.010.3560.3970.2791388913929137016.369__
191355___________ +1.18 +1.190.0250.0320.0661381416307164426.1002_6-phosphogluconolactonase|multicopysupressoroflos1-1
195535___________ -1.06 +1.020.3900.2030.7682037219230208496.1550_
*19411____________ +3.83 +3.840.0000.0010.0011628862459625966.2096_hypotheticalprotein
194131___________ +1.32 +1.160.0090.0090.0601293217025150326.2617_
191156___________ +1.01 +1.020.7430.7220.5461184411924121336.3132_
192437___________ +1.22 +1.080.0290.0170.2681216014859131216.3615_Arpcomplexsubunit
*192593___________ +1.36 +1.340.0020.0040.0124356259338583476.4106_
*195698___________ -1.99 -2.020.0000.0000.0014618623157229196.4577_
195610___________ -1.03 -1.050.1060.1140.1571745616992166876.5062_ornithinecarbamoyltransferase
192312___________ +1.33 +1.280.0030.0060.0121292617203165866.5538_ferricreductase
19734____________ -1.12 -1.030.7060.4400.9062747022447942678296.6009_aldohexosespecificglucokinase
*193431___________ +1.74 +1.900.0000.0020.0012012134946381416.6474_mitochondrialDNApolymerasecatalyticsubunit
193117___________ -1.12 -1.110.0970.0970.1602000017818179576.6928_mycelialsurfaceantigen,similartoRBT5
*194833___________ -6.32 -8.830.0000.0000.00037069858699419996.7378_malatesynthase
196443___________ -1.45 -1.220.0990.0460.5712245815479183416.7811_enoyl-CoAisomerase|delta3-cis-delta2-trans-enoyl-CoAisomerase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*193265___________ -1.35 -1.080.0300.0140.5713061222631283846.8265_N2,N2-dimethylguanosine-specifictRNAmethyltransferase
195459___________ +1.26 +1.150.0080.0080.0701795822632205966.8696_
195892___________ +1.23 +1.280.0030.0120.0071896923249242546.9145_ubiquitin-proteinligase
*194683___________ +1.39 +1.160.0080.0100.0391666423136193086.68___
*193599___________ +1.58 +1.280.0160.0170.0673486855225445976.704__
*195755___________ +1.89 +1.510.0010.0030.0062254642506339676.1303_
193140___________ +1.25 +1.170.0090.0090.0651257615732147036.1851_hypotheticalprotein
*194635___________ +1.89 +1.870.0020.0070.0061325325074248366.2374_
*19166____________ +2.22 +1.810.0000.0010.0012688259602486726.2903_
195051___________ +1.42 +1.390.0060.0110.0191291018366179356.3385_conservedhypotheticalprotein
*193684___________ -2.55 -3.640.0000.0000.00010753442143295666.3882_
195503___________ +1.16 +1.160.0090.0140.0341368115864158146.4351_hypotheticalprotein
195776___________ +1.08 -1.290.1650.5860.0882643592857522050806.4848_ubiquitin-proteinligase
*196154___________ +1.13 -1.010.0140.0080.4628647598109853426.5315_conservedhypotheticalprotein
196356___________ -1.26 -1.220.0020.0070.00611863938897176.5785_snRNP(U4/U6)-associatedsplicingfactor|RNAsplicingfactor
*196092___________ +2.18 +2.130.0020.0060.0041735237823370386.6248_
19826____________ -1.17 -1.130.0080.0150.021115629882102286.6717_hypotheticalprotein
196902___________ -1.14 -1.090.0240.0600.0341222110710111626.7166_Dead-boxprotein|RNAhelicase
196072___________ -1.15 -1.160.0070.0270.0121175610228101176.7616_hypotheticalprotein
197161___________ -1.10 -1.130.0160.0810.0171161010578102916.8062_
197056___________ -1.15 -1.140.0100.0190.0251172410161102906.8497_dicarboxylicaminoacidpermease
197588___________ -1.23 -1.130.0130.0350.023117649601104206.8936_conservedhypotheticalprotein
19618____________ +1.24 +1.140.0080.0070.0681239515414140816.385__hypotheticalprotein
193188___________ +1.28 +1.210.0030.0050.0181830623420221296.1024_
196249___________ +1.23 +1.170.0080.0090.0421398917151163856.1565_
191485___________ -1.19 -1.350.0140.0460.0212672722427198296.2109_mitochondrialribosomalprotein
*194984___________ +1.55 +1.600.0000.0020.0011613825046258866.2631_
194976___________ +1.32 +1.260.0060.0090.0241491619746188316.3146_
19752____________ +1.21 +1.090.0100.0110.0591326215988144726.3631_
*195551___________ +3.06 +2.940.0000.0000.0002648380919778186.4121_requiredfornormalchromosomesegregationandspindleintegrity
194763___________ +1.32 +1.250.0010.0030.0051720922722214636.4592_hypotheticalprotein
191239___________ +1.05 +1.060.0670.0860.1041222212794129366.5078_hypotheticalprotein
192297___________ +1.29 +1.200.0020.0040.0071681021698202296.5553_
*196263___________ -1.81 -2.030.0000.0000.00010085055653495866.6022_conservedhypotheticalprotein
193676___________ +1.25 +1.260.0040.0130.0101480418572186056.6487_putativemethyltransferase
*193104___________ -1.18 -1.090.0300.0300.0976595655719603086.6941_alkalinedihydroceramidase
*196960___________ +2.65 +2.630.0010.0030.0011628143123428576.7391_
196425___________ +1.09 +1.040.1430.0750.4811255213720130626.7827_
*193278___________ +3.85 +4.250.0000.0000.000287771106921221916.8278_glycogen(starch)synthase
197460___________ +1.26 +1.350.0020.0110.0051447718202195176.8712_conservedhypotheticalprotein
*195876___________ +2.02 +1.990.0000.0000.0004468690467887366.9161_hypotheticalprotein
193433___________ +1.23 +1.140.0210.0150.1631344516572153176.92___
192655___________ +1.30 +1.270.0050.0090.0151285016728162666.722__
191225___________ +1.46 +1.220.0560.0820.0841340919631163836.1316_hypotheticalprotein
*191971___________ +2.32 +2.420.0000.0010.0012042047279495046.1864_conservedzincfingerprotein
192532___________ +1.38 +1.240.0020.0030.0101407019460175036.2387_
62918____________ +1.09 +1.060.0540.0350.2381233513432130246.2918_
195126___________ +1.07 +1.070.7590.8750.5141601917079170946.3404_
19418____________ +1.36 +1.300.0030.0040.0171265417259164766.3897_KontrollerOfGrowth
193504___________ +1.06 -1.090.4150.4270.3286106364498559466.4364_ribosomalprotein
*193000___________ +1.61 +1.660.0000.0010.0012552841209423466.4866_
196167___________ -1.17 +1.040.2660.1220.8837689865990799136.5328_1-Acyldihydroxyacetonephosphatereductase
19998____________ +1.30 +1.280.0020.0060.0081684721913215006.5800_hypotheticalprotein
19399____________ +1.10 +1.210.1160.1440.1421395201541561682036.6265_ser/thrproteinkinase
19517____________ +1.09 +1.050.0930.0450.5212157823582225996.6729_Histone-liketranscriptionalactivatorofrespiratoryfunctions
*196915___________ +1.17 +1.260.0060.0270.0092744632049345846.7179_requiredfordoublestrandbreakformation&resection
*196531___________ -2.11 -2.260.0000.0010.00010193448250452006.7629_NADH-ubiquinoneoxidoreductase49kDasubunit,mitochondrialprecursor
*197176___________ +2.27 +2.230.0000.0010.0011686438346376866.8076_nicotinatephosphoribosyltransferase
*197349___________ +1.62 +1.760.0020.0060.0052327237591410376.8509_chitinsynthaseregulatoryfactor
*197600___________ -3.31 -2.670.0000.0000.0003620901093161356536.8948_glutathione-dependentformaldehydedehydrogenase
194743___________ +1.14 +1.040.6840.6450.5131369815590142056.404__
191433___________ +1.11 +1.050.0560.0240.6941649518353172866.1039_predictedacetyltransferasesandhydrolaseswiththealpha/betahydrolasefold
191806___________ +1.14 +1.050.0510.0330.2331290914702135836.1581_hypotheticalprotein
191047___________ +1.17 +1.080.0240.0200.1201240214571134336.2128_
191342___________ +1.03 +1.040.6500.3880.8961569016104162426.2646_
194312___________ +1.26 +1.110.0320.0350.0891458418331161606.3165_
194186___________ +1.20 +1.140.0190.0170.0991260715138143126.3643_phosphorylcholinetransferase|cholinephosphatecytidylyltransferase
19746____________ +1.10 +1.040.2770.1280.8591225313421127716.4135_hypotheticalprotein
194305___________ -1.02 -1.030.8650.8500.6601377113524134026.4610_conservedhypotheticalprotein
196012___________ +1.13 +1.000.0450.0200.7321242614020124416.5092_conservedhypotheticalprotein
*192340___________ +1.50 +1.700.0000.0010.0002131631993362486.5569_
196275___________ -1.02 +1.020.6150.4140.6672250422047229236.6034_ribosomalproteinkinases
19431____________ -1.02 +1.000.7870.6520.6612166721273217506.6500_potentialfungalZn(2)-Cys(6)binuclearclusterdomain
195179___________ +1.02 -1.010.5120.2780.8771211412315119566.6957_secretedlipase
193995___________ -1.07 +1.010.5800.3470.7742436222858244986.7408_calpain-likeproteaseinvolvedinproteolyticprocessingofRim1p/Rim101p,cysteineprotease
196408___________ +1.07 +1.080.1390.1290.2052271424384244346.7844_
195304___________ -1.02 -1.040.6860.6670.5031427314061137306.8293_hypotheticalprotein
*197477___________ +1.52 +1.760.0000.0000.0002869843744506116.8729_GTPase-activatingprotein
*19122____________ +1.77 +1.320.0050.0060.0371491026417197276.139__
192682___________ -1.03 -1.080.3240.8660.1661195411598110606.742__
191611___________ +1.36 +1.240.0030.0050.0141292817541159956.1337_
193199___________ +1.26 +1.180.0070.0090.0311286316164152286.1882_amatinglocusphosphatidylinositol4-kinase
194819___________ -1.02 +1.020.3970.6260.2392077620351211426.2400_hypotheticalprotein
193376___________ +1.11 +1.090.0360.0310.1341321914722144696.2936_
63418____________ +1.21 +1.110.0400.0300.1691235614911137166.3418_
195218___________ +1.14 +1.020.0540.0270.4561504017110153526.3909_
*191797___________ +2.96 +3.080.0000.0020.0011610047630495976.4376_conservedhypotheticalprotein
191321___________ +1.28 +1.210.0020.0050.0101473618832178426.4881_
191580___________ -1.19 -1.140.0100.0200.024115899779101986.5340_hypotheticalprotein
19589____________ -1.26 -1.170.0070.0150.018117009308100386.5816_Rab5-likeGTPaseinvolvedinvacuolarproteinsortingandendocytosispostvesicleinternalization
19387____________ -1.16 -1.100.0120.0250.0261185610237107646.6277_largesubunitofthenuclearpre-mRNAcap-bindingproteincomplex
19532____________ -1.19 -1.140.0030.0060.0161209710207106556.6744_hypotheticalprotein
193296___________ -1.19 -1.160.0040.0110.010116979870100906.7191_hypotheticalprotein
196517___________ -1.17 -1.130.0050.0120.0151174210052104306.7643_Zn-bindingnucleotideexisionrepairosome
197188___________ -1.22 -1.120.0040.0100.013117949687105586.8089_60Slargesubunitacidicribosomalproteina1
197362___________ -1.17 -1.130.0080.0330.013117019996103466.8522_glucansynthasesubunitinvolvedincellwallassembly
197613___________ -1.13 -1.140.0130.0640.0151168810365102266.8961_translationinitiationfactor3subunit
6419_____________ +1.28 +1.140.0040.0050.0391288016531146566.419__
*194690___________ +1.51 +1.350.0040.0060.0161291219470174246.1056_
193558___________ +1.28 +1.100.0060.0060.0661719522005189736.1604_p24proteininvolvedinmembranetrafficking

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
191077___________ +1.37 +1.170.0020.0030.0201655622723194506.2145_
*194956___________ +1.85 +2.040.0000.0030.0011933435856395246.2659_
19269____________ +1.10 +1.040.4510.2420.7922351625814243406.3180_seryl-tRNAsynthetase
194744___________ +1.23 +1.140.0060.0070.0471620819875184156.3657_
*191690___________ +1.68 +1.520.0020.0040.0061631127360247726.4150_
*191193___________ +2.27 +2.680.0000.0000.000516441170411384686.4630_
196129___________ -1.40 -1.410.0030.0100.0062419217281171266.5111_
192325___________ +1.30 +1.220.0040.0080.0131554720170189596.5583_91kDatau91subunitoftranscriptionfactorIIIC(TFIIIC)
*194943___________ -1.28 -1.620.0000.0100.00010302280334637096.6047_mannose-1-phosphateguanyltransferase
19446____________ +1.26 +1.180.0150.0240.0411503618949177066.6515_hypotheticalprotein
195166___________ +1.20 +1.150.0190.0260.0521663520001191926.6970_regulatorofCdc7kinase
194007___________ +1.07 -1.010.5050.2770.8262564227522254206.7420_conservedhypotheticalprotein
196392___________ -1.02 +1.030.9930.9450.9351951819150201856.7862_hypotheticalprotein
195318___________ +1.15 +1.060.0420.0310.1731555417815165586.8306_
*197489___________ +1.31 +1.300.0020.0050.0041982526024257456.8741_GTPase-activatingproteinoftherho/racfamily
192919___________ +1.31 +1.140.0120.0070.2371248316336142446.166__
192433___________ +1.20 +1.130.0060.0070.0461319615860148556.762__
19799____________ +1.41 +1.240.0030.0040.0271341018955166726.1353_betasubunitofheterotrimericGprotein
*192826___________ +1.47 +1.280.0030.0050.0151567823008201466.1900_hypotheticalprotein
193949___________ +1.38 +1.320.0030.0060.0111520820964200856.2415_
194488___________ +1.09 +1.020.1400.0640.6751299614170133166.2948_
191827___________ +1.26 +1.120.0360.0210.3001290816271144516.3434_hypotheticalprotein
196018___________ -1.04 +1.010.9340.8310.8032707526028273936.3922_phospholipid:diacylglycerolacyltransferase
193205___________ -1.05 -1.130.0250.0860.0282329922287206346.4394_mitochondrialribosomeLSUproteinL36
194786___________ +1.16 +1.100.0230.0220.0951301715145143296.4896_hypotheticalprotein
191402___________ +1.03 +1.050.9910.9180.9532237623117234356.5355_cytoplasmicchaperoninoftheCctringcomplex
196378___________ +1.14 +1.080.0390.0280.1811286014646139226.5830_conservedhypotheticalprotein
*195079___________ +1.20 +1.210.0040.0120.0103566042796431536.6297_ABCtransporter
195441___________ +1.13 +1.110.0260.0210.1251534417318169656.6757_20Sproteasomesubunit(alpha4)
193309___________ +1.34 +1.240.0020.0030.0131727923138213836.7204_hypotheticalGAGprotein
196506___________ +1.14 +1.090.0210.0170.1191255114362136606.7656_
197201___________ +1.09 +1.200.3830.6180.2301339751460511610376.8101_structuralconstituentofcytoskeleton
*197374___________ +2.69 +2.920.0010.0030.0021785547982520866.8534_zincfingertranscriptionfactor
197626___________ +1.00 -1.010.5400.2950.9352225222295221236.8974_mRNAcap-bindingproteineIF4E,translationinitiation
194865___________ +1.02 +1.020.3790.1850.9791186612141120736.440__
191591___________ +1.06 +1.030.5040.2690.9321740718416179886.1069_acetyl-CoAacetyltransferase|acetoacetylCoAthiolase
61622____________ +1.08 +1.050.2140.1250.4581278013833133966.1622_
191270___________ +1.14 +1.110.0390.0230.2611211013842134506.2163_
193163___________ +1.10 +1.040.1400.0630.6831183813049123606.2675_
194120___________ +1.07 +1.050.3760.1950.7581213712943126966.3193_cellmorphogenesis,cytoskeletalregulationandbudformation
192395___________ +1.08 +1.010.2490.1120.9761316014251132686.3678_positiveregulatorofmeiosis,ser/thrproteinkinase
191376___________ +1.19 +1.060.0850.0620.2271230414609130676.4162_syntaxin|post-Golgit-SNARE
193552___________ +1.16 +1.150.0200.0400.0381482417241170226.4649_nuclearporeprotein
196230___________ +1.06 +1.020.3550.1940.6481224812933125176.5126_enhancesfunctionofnuclearexonucleaseRat1
191941___________ +1.05 +1.010.4340.2350.7511224912865123206.5598_spindlepolebodyprotein
194166___________ +1.09 +1.070.2830.1850.4331264113769135826.6060_fungalZn(2)-Cys(6)binuclearclusterdomain
*196634___________ +1.35 +1.330.0010.0030.0062408232560319326.6531_vacuolarATPaseV1domainsubunitB
66983____________ -1.00 +1.010.6420.3990.7941182411785119456.6983_
194021___________ -1.01 -1.010.7160.8320.4771691716715167506.7433_
194580___________ -1.01 -1.030.9550.8980.8161234312195119296.7879_conservedhypotheticalprotein
195328___________ +1.08 +1.010.2220.1220.5161262613580127046.8320_
*197502___________ +2.52 +2.700.0000.0000.0002890372908780646.8754_hypotheticalprotein
193954___________ -1.13 -1.110.0140.0260.0341167410295105546.181__
194057___________ +1.01 -1.080.4650.5660.3141193112051110966.784__
1975_____________ +1.28 +1.160.0030.0050.0141430518257165476.1370_possibleexocystcomponent
193932___________ -1.06 -1.080.2350.4860.1441173911064108556.1913_
194948___________ +1.16 +1.130.0060.0090.0281310815194148456.2434_
19192____________ -1.15 -1.130.0140.0420.0211173310240103666.2965_conservedhypotheticalprotein
195205___________ +1.19 +1.120.0410.0400.1161396716664156956.3448_hypotheticalprotein
195297___________ +1.33 +1.210.0040.0050.0281309817473158706.3936_
*194040___________ +1.30 +1.200.0030.0060.0112402231318287086.4406_
195729___________ +1.34 +1.170.0060.0070.0431528820548178776.4908_transcriptionfactor
192135___________ -1.13 -1.120.0180.0680.0221209710663108056.5368_
*193877___________ +1.96 +1.920.0010.0030.0031794035195344386.5849_hypotheticalprotein
194393___________ -1.08 -1.120.0130.0480.0191177010931105336.6314_nuclearcitratesynthase
196663___________ -1.13 -1.160.0090.0360.0141359412049117416.6772_ribosomalproteinS25
19334____________ -1.10 -1.080.0350.0490.0701168510616108186.7218_hypotheticalprotein
195274___________ -1.12 -1.120.0140.0490.0191156110277103316.7669_
197213___________ -1.15 -1.150.0050.0170.0111178010275102236.8113_ATP-dependentRNAhelicase
197386___________ -1.16 -1.110.0110.0230.0261165210032104976.8546_assemblyofmitochondrialrespiratorycomplexes
197642___________ +1.08 +1.070.1060.0640.3291262013595134676.8989_
19693____________ +1.26 +1.130.0070.0060.0901265916003143146.456__
191673___________ +1.32 +1.260.0030.0050.0111291217047162136.1084_serine/threonineproteinphosphatase
*193080___________ +1.67 +1.600.0010.0040.0061599526778255376.1638_
*19465____________ +1.44 +1.480.0030.0090.0102882441393425206.2178_
*193158___________ +1.63 +1.850.0010.0050.0021432523278264716.2691_involvedinmeioticnucleardivision
194072___________ +1.03 +1.010.3750.1960.7351214912463123046.3206_
19686____________ +1.34 +1.210.0080.0110.0321304817471157336.3693_conservedhypotheticalprotein
*195484___________ -1.68 -1.630.0000.0010.0008488550570522176.4178_3-phosphoserinetransaminase
195493___________ +1.13 +1.020.0710.0300.8378582497208874286.4664_smallnuclearGTPaseoftherassuperfamily
193906___________ +1.05 +1.020.1620.0720.7521218412757124386.5142_hypotheticalprotein
*191849___________ +1.29 +1.430.0010.0060.0021842223741264356.5616_conservedhypotheticalprotein
194180___________ +1.08 -1.000.1690.0910.4891743418899174226.6074_signalrecognitionparticlereceptorinvolvedinmembraneproteininsertionintotheER
*196645___________ +1.99 +1.740.0000.0000.0003551670768619116.6543_
*196847___________ +1.41 +1.430.0010.0050.0041745224569249536.6996_conservedhypotheticalprotein
194032___________ +1.01 +1.060.8190.5700.8934556046035483506.7447_non-ATPaseunitof26Sproteasomecomplex
194594___________ +1.05 +1.010.3130.1610.6871161812161117656.7893_clathrinlightchain
195346___________ +1.30 +1.100.0130.0090.1541404218279154266.8336_
197516___________ -1.02 -1.110.0190.3430.0122564525136230606.8767_
191100___________ +1.36 +1.130.0050.0050.0501281417444144846.200__
194117___________ +1.27 +1.150.0040.0040.0481270616200145636.805__
*191300___________ -1.89 -2.170.0000.0010.0015578529526257306.1387_conservedhypothticalprotein
193359___________ -1.02 -1.010.8830.7640.7391171711494115596.1928_
*192290___________ +1.61 +1.510.0000.0010.0021619726104244776.2450_1-phosphatidylinositol3-kinase
191107___________ +1.18 +1.180.0200.0300.0471313315544154486.2983_conservedhypotheticalprotein
*192916___________ -1.75 -2.040.0010.0080.0028991251511441806.3462_hypotheticalprotein
193767___________ +1.18 +1.080.0140.0090.2221253914805135116.3953_
*195586___________ +1.83 +1.770.0010.0020.0031629029731288266.4428_pheromone-inducedprotein,suppressorofsac1mutation
*191067___________ +2.32 +2.580.0000.0000.0003870089657997666.4922_phosphoglyceratemutase
192151___________ -1.28 -1.260.1080.1310.1386774753082535606.5386_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
193128___________ -1.14 -1.060.3870.2700.4687910269086749216.5865_t-SNARE-interactingproteinthatfunctionsinER-to-Golgitraffic
*194381___________ +1.26 +1.450.0000.0010.00176990973361117726.6326_polyphosphatesynthetase
*196679___________ +1.95 +1.660.0010.0020.0081413427509234876.6788_aldolase
*19347____________ +1.74 +1.590.0010.0010.0033560162001566346.7231_hypotheticalprotein
*195260___________ +1.25 +1.270.0100.0200.0254341854072549276.7682_proteasomeregulatorysubunit
*197227___________ +1.30 +1.310.0000.0010.0012794036414367186.8127_conservedhypotheticalprotein
197424___________ +1.14 +1.130.0510.0870.0705993068599675076.8558_
197658___________ -1.08 -1.030.1560.1280.2512779625694270396.9007_
191571___________ +1.07 +1.040.2000.1330.3661245213315129216.478__Ady2-Fun34likeFamily,possibletransmembraneacetatefacilitator/sensor
*191091___________ +1.64 +1.930.0010.0040.0011887430900364616.1101_nucleolarproteinrequiredfor60Sribosomebiogenesis
192618___________ -1.18 +1.020.1100.0460.8693790532048387216.1653_homoserineO-acetyltransferase
193718___________ +1.68 +1.330.0140.0100.1541297221752172406.2195_peptidetransporter
193629___________ +1.17 +1.090.0270.0170.2101254914659136596.2710_WDdomainprotein
191029___________ +1.09 +1.040.1590.0990.3701178112897122896.3222_nuclearribonucleasePsubunit(RNaseP)|requiredforprocessingoftRNAand35SrRNA
196482___________ +1.06 +1.060.1400.1190.2281233113088130596.3712_hypotheticalprotein
*194502___________ +1.13 +1.180.0380.0640.0603038234223357286.4192_
192580___________ +1.20 +1.170.0160.0180.0661270415284149036.4681_similartoHst1pandSir2pputativehistonedeacetylases
19217____________ +1.07 +1.040.1810.1100.4071274613632132446.5156_zincfingerprotein
*19327____________ +1.74 +1.360.0030.0040.0201398324294190426.5631_histonevariantinvolvedinchromatinandtranscriptionalcontrol
192177___________ +1.05 +1.010.2340.1120.7171186712497120276.6086_
19666____________ +1.06 +1.030.1180.0520.7421419815057146496.6560_DNAdamageresponsecellcyclecheckpointprotein
196859___________ +1.04 +1.020.1750.2270.1671244112879126566.7008_hypotheticalprotein
*192094___________ +1.09 +1.150.0260.0950.0282738929985314656.7461_memberofthekaryopherin-betafamilywithpossibleroleinnucleartransportandregulationofpleiotropicdrugresistance
194608___________ +1.05 +1.020.2800.7710.1441207212721123056.7907_pyruvatedecarboxylaseI
195364___________ +1.18 +1.130.0230.0260.0711487617608167626.8353_rnabindingprotein
*197531___________ -1.36 -1.140.0260.0210.1344428832516390096.8784_
*1943_____________ -1.21 -1.500.0000.0220.0003541429232235916.8____hypotheticalprotein
196277___________ +1.28 +1.210.0040.0060.0201294116601155956.501__
*193957___________ +1.22 +1.140.0150.0110.1482790233995317186.1119_GTPcyclohydrolase
*194336___________ -1.36 -1.920.0000.0020.0002102081550431092246.1675_ribosomalsmallsubunitprotein
*196463___________ +1.33 +1.210.0010.0020.0143803850582460486.2211_
*192711___________ +1.16 +1.120.0080.0120.0302321827044259896.2727_RNApolymeraseIIElongatorsubuni
*191729___________ +2.49 +2.130.0000.0010.0011770343995377666.3236_hypotheticalprotein
*192799___________ +1.20 +1.140.0070.0110.0292679632253304276.3728_essentialforGPIanchorattachment
192343___________ +1.44 +1.450.0880.2670.0641615623313233786.4209_putativeubiquitinreceptorimplicatedinvacuolartargetingofplasmamembraneproteins
192738___________ +1.11 +1.130.6280.3960.7525691963202645076.4694_highaffinitysulfatepermease
*192422___________ -1.29 -1.380.0010.0060.0014609835851334426.5173_
*193970___________ +1.53 +1.660.0020.0070.0051786427344295946.5646_conservedhypotheticalprotein
193420___________ +1.07 +1.070.0630.1120.0751270713547135456.6105_hypotheticalprotein
*192774___________ +2.17 +2.430.0000.0010.0011875240618455326.6579_
191900___________ +1.14 +1.190.0070.0260.0131564317903186326.7022_
*192079___________ +1.42 +1.320.0040.0040.0383927055825517546.7476_pterin-4a-carbinolaminedehydratase
*194622___________ +2.61 +3.060.0000.0020.0012283259617699196.7921_hypotheticalprotein
*197285___________ -1.37 -1.570.0000.0010.0007739856515493946.8366_conservedhypotheticalprotein
*196831___________ +2.30 +2.630.0010.0040.0031663638273437726.8800_pre-mRNAprocessingRNA-helicase
42957____________ +1.00 -1.040.5780.6150.4071221812249117084.2957_
19227____________ -1.03 -1.210.2910.4150.2053193330900263616.215__cytochrome-coxidase,subunitVII
191651___________ +1.34 +1.190.0030.0040.0241405418824166746.827__hypotheticalprotein
*192521___________ +1.85 +1.640.0010.0020.0031540128541253156.1402_
193512___________ +1.15 +1.090.0170.0190.0661689419413183666.1947_
193610___________ +1.19 +1.190.0070.0110.0231342716033159236.2466_transmembraneprotein
*19797____________ +3.42 +2.490.0000.0000.0002431783194605206.2998_
*19137____________ +2.52 +2.030.0000.0020.0011546938922314296.3477_acetyltransferase
194253___________ +1.18 +1.190.0120.0210.0311282415151152046.3970_
*19306____________ +1.78 +1.640.0000.0010.0012023036036331416.4444_interaptininvolvedinERtoGolgiproteintransport
*192843___________ +2.26 +2.010.0000.0000.0002382195386184796786.4937_GTP-bindingprotein,rhosubfamily
*196181___________ -1.26 -1.240.0020.0050.0043467527450280176.5402_
*192265___________ +1.41 +1.420.0010.0020.0023957855677560536.5881_subunitofSWI/SNFtranscriptionactivationcomplex
*195106___________ +1.50 +1.710.0010.0080.002739551112321263016.6344_betatransducin
196694___________ +1.18 +1.130.0070.0090.0301470017375166726.6804_
*194435___________ +1.82 +2.140.0040.0100.0121379825113294996.7246_
195247___________ +1.03 -1.030.4550.2450.7935083852473495736.7695_conservedhypotheticalprotein
197242___________ +1.21 +1.190.0100.0150.0311392816846165506.8141_
*197413___________ +1.47 +1.480.0010.0020.0021838526941272116.8573_lowhomologytoproteininvolvedinDNArepair
*197673___________ -1.17 -1.190.0270.0540.0435467746707458986.9021_snRNA-associatedprotein,snRNP
*194496___________ +1.37 +1.310.0010.0020.0024306058928564716.31___conservedhypotheticalmembraneprotein
*19712____________ +1.73 +1.540.0010.0030.0061488025794229886.523__
19193____________ +1.19 +1.190.0070.0100.0341313615591155806.1142_
193732___________ +1.37 +1.310.0010.0030.0031753023930228916.1690_membrane-boundnon-hemedi-ironoxygenaseinvolvedinlipidmetabolism|C-4sterolmethyloxidase
193601___________ +1.31 +1.250.0030.0060.0151359217872170236.2226_replicationfactorATPase
*193969___________ +1.32 +1.150.0090.0080.0901355817950156556.2746_heat-shockrelatedprotein
*195558___________ +1.86 +1.790.0000.0010.0011939636141347686.3253_
*19849____________ +1.65 +1.610.0010.0040.0041324621793213216.3745_
194413___________ -1.05 +1.040.6140.6860.4173248433084723363866.4226_
194656___________ +1.11 +1.130.0090.0120.0411427815904161766.4707_lowsimilaritytoABCtransporters
192406___________ +1.12 +1.080.0520.0610.1011533317142165856.5187_
193983___________ +1.15 +1.150.0040.0130.0091813620905209096.5659_conservedhypotheticalprotein
*192903___________ +1.93 +1.660.0000.0010.0012527448860418976.6118_
*192762___________ -2.16 -1.970.0000.0000.0012984241382421516986.6590_alkylhydroperoxidereductase
*191886___________ +1.43 +1.550.0010.0050.0013102644416479846.7034_
192067___________ -1.00 -1.100.0280.7860.0152379123762216826.7488_nitrogenfixingprotein
197009___________ +1.06 +1.070.3280.5880.1941425815172152626.7934_
*197298___________ -1.72 -1.550.0010.0020.0023047617749196516.8380_
*196816___________ -2.32 -1.780.0000.0000.0018840338059497376.8815_aldehydereductase
Caexg2___________ -1.09 -1.050.2060.5870.113121451118411552Caexg2_
*194147___________ -1.33 -1.070.0010.0010.2297062052990657296.234__
191207___________ +1.22 +1.110.0090.0100.0461260615417139776.840__hypotheticalprotein
*194784___________ +1.44 +1.310.0020.0030.0151404620249184206.1418_
*191915___________ +1.69 +2.020.0010.0040.0022580843698521696.1963_
*191978___________ -1.42 -1.320.0020.0030.0143324323375252646.2482_glycerophosphoinositolpermease
191248___________ -1.06 -1.090.1390.1370.1924316640709394586.3011_45kDasubunitofRNApolymeraseII
*194266___________ +1.19 +1.290.0030.0180.0041699620268218856.3491_septin
*194346___________ +1.54 +1.330.0020.0030.0111543423787205796.3989_
*195517___________ +1.29 +1.330.0050.0320.0072581033354342066.4459_alcoholdehydrogenase
*195851___________ +1.16 +1.290.0030.0330.0042715431540350696.4953_dipeptidylaminopeptidase
*196208___________ -1.66 -1.810.0000.0010.0015591333761309566.5418_
*192250___________ -1.83 -1.700.0000.0000.00110157655475597376.5896_spermidinesynthase|putrescineaminopropyltransferase
*192002___________ +1.46 +1.540.0000.0010.0002623938262403136.6358_nucleoporin
*194118___________ +1.28 +1.370.0020.0040.0132935137553401266.6818_
*194447___________ +1.78 +1.740.0010.0020.0021613428706280996.7260_mitochondrialcarrierprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
195233___________ +1.02 -1.020.2590.8850.1281386814077135736.7709_hypotheticalprotein
197257___________ -1.07 -1.030.5430.3250.7293634033971351586.8157_DNAmismatchrepair
*197428___________ +2.13 +2.100.0000.0010.0002146245739451246.8588_apurinic/apyrimidinicendonuclease/3'-repairdiesterase
196002___________ -1.17 -1.150.0030.0050.0182039617495176786.9035_ribosomalproteinL8B(L4B)(rp6)(YL5)
194079___________ +1.32 +1.180.0020.0040.0121463619353172656.48___
19846____________ +1.23 +1.140.0110.0110.0571249115403142246.541__
191805___________ +1.14 +1.140.0100.0130.0401459316623166156.1160_peroxisomalproteininvolvedinimportofperoxisomalmatrixproteins
194691___________ +1.08 +1.050.0620.0460.2041250713495131166.1708_
*191390___________ +1.93 +1.590.0010.0020.0042034239187323266.2242_
194217___________ +1.08 +1.110.0390.0440.0941350214630150286.2762_
192859___________ +1.16 +1.180.0170.0230.0511411816367166416.3272_
193457___________ +1.18 +1.120.0150.0140.0861272814958142886.3760_
*191285___________ +1.94 +1.790.0000.0010.0014222881989755766.4240_conservedhypotheticalprotein
*19575____________ +1.42 +1.360.0010.0030.0052168430766294616.4723_
194284___________ +1.01 +1.000.5960.3460.8621265912770127236.5201_
196139___________ +1.03 +1.020.3360.2920.3381300413336133146.5674_
192891___________ -1.06 -1.110.0450.1270.0461491414049134136.6131_ATPase
194242___________ +1.35 +1.240.0010.0020.0061576321298195126.6603_serine/threoninekinase
*191872___________ -1.73 -2.030.0000.0010.00013217776341652176.7048_
*193809___________ +1.49 +1.400.0040.0090.0122001829863279606.7502_
*197022___________ +2.42 +2.420.0000.0010.0021952247260472796.7948_hypotheticalprotein
*197312___________ -1.03 -1.250.0030.0640.0035503753667441026.8393_3-hydroxy-3-methylglutarylcoenzymeAsynthase
*196803___________ +1.36 +1.370.0010.0040.0041977826898270696.8828_UDP-galactosetransporter
Cancx1___________ +1.04 -1.020.4830.3180.571118371232811569Cancx1_
194063___________ +1.49 +1.290.0010.0020.0091331819875171806.249__
192781___________ +1.31 +1.130.0080.0070.0661273816693144276.859__Ca/calmodulin-dependentser/thrproteinkinase
192634___________ +1.29 +1.340.0030.0090.0061311016899176026.1440_
191953___________ +1.25 +1.200.0040.0090.0131532419090183706.1979_hypotheticalprotein
193682___________ -1.00 +1.090.4540.5650.3042006819987219466.2497_generationofmannoproteinlayerofthecellwall|putativephosphatase
193228___________ +1.15 +1.120.0180.0200.0701343715441150346.3027_conservedhypotheticalprotein
193966___________ +1.36 +1.270.0010.0040.0041297617594164516.3505_congoredhypersensitive,Cellwallprotein
192940___________ +1.24 +1.150.0060.0080.0251309316274150526.4004_ER-to-Golgiv-SNARE
*193176___________ +1.26 +1.300.0070.0100.0313225840577418026.4473_unknownfunction
*192467___________ +1.41 +1.460.0030.0060.0101587822440232366.4968_RNApolIItranscriptioncofactor
*196193___________ +1.61 +1.620.0020.0050.0071528724604247996.5431_TFIIDsubunit,5-primeend
194929___________ -1.00 -1.040.4440.7920.2492331423251223196.5909_involvedinexpressionofmitochondrialCOX1
191409___________ +1.11 +1.190.0740.1140.0943931743710469106.6378_vacuolarmembraneprotein
*194102___________ -1.30 -1.320.0030.0100.00710104677514766006.6833_
*19904____________ +1.23 +1.150.0040.0070.0162346428962269956.7273_hypotheticalprotein
*196976___________ +1.74 +1.960.0000.0010.0002338240681458436.7722_multidrugeffluxprotein
197271___________ +1.17 +1.100.0080.0090.0551737320322190746.8171_hypotheticalprotein
197442___________ -1.11 -1.100.0120.0190.0352894426061263226.8602_lowhomologytomismatch-specificthymineDNAglycosylase
195987___________ +1.09 +1.090.0590.0430.2031398415302152706.9050_conservedhypotheticalprotein
19634____________ +1.32 +1.200.0020.0050.0121337117615161016.71___hypotheticalprotein
192402___________ +1.46 +1.240.0020.0030.0181525322309189056.563__
19145____________ +1.24 +1.230.0030.0050.0121331016478163466.1178_
195578___________ +1.28 +1.150.0060.0060.0561284116453147596.1725_
62259____________ +1.09 +1.070.0430.0420.1141523116602163606.2259_
*191150___________ +1.34 +1.420.0010.0030.0011922625718272276.2781_zincfingertranscriptionfactor
193615___________ -1.03 +1.080.4370.7520.2493260731794350926.3285_conservedhypotheticalprotein
194363___________ +1.27 +1.180.0030.0060.0121279616188151036.3774_
*191833___________ +1.75 +1.880.0060.0260.0101049301840821969116.4253_nucleolarpseuduridinesynthaseandputativemicrotubulebindingprotein
*193349___________ +1.70 +1.850.0000.0010.00055841948791031036.4740_
194809___________ -1.23 -1.240.0020.0060.0062706821980218736.5215_mevalonatekinase
*19593____________ +1.68 +1.930.0020.0060.0051407023571272246.5686_
195834___________ +1.08 +1.060.0420.0350.1452161623422229616.6144_suppressorofmRNAexportmutant|importin-betalikegene|karyopherinbetafamilymember|putativebeta-karyopherin
194227___________ +1.22 +1.280.0000.0020.0011566419084200146.6618_hypotheticalprotein
*19505____________ -1.57 -1.400.0000.0010.00213582886731968466.7066_adenylatecyclase-associatedprotein
*193822___________ -1.76 -1.600.0000.0000.0013737002125982330876.7517_inositolphosphorylceramide-BC-26hydroxylase|ERdesaturaserequiredforthehydroxylationoftheverylongchainfattyacid(VLCFA)
197035___________ +1.09 +1.140.0900.1930.0801509616397172026.7961_subunit2ofreplicationfactorC|DNAbindingproteinandATPasethatactsasaprocessivityfactorforDNApolymerasesdeltaandepsilonandloadsproliferatingcellnuclearantigen(PCNA)onDNA
197324___________ +1.03 +1.040.4400.6180.2761663617213172846.8405_pyrimidineprecursorbiosynthesisenzyme
*196790___________ +1.87 +2.000.0000.0020.0014063876154814156.8841_negativegrowthregulatoryprotein
41867____________ +1.04 +1.000.4880.2600.8901191112386119234.1867_
*19494____________ +1.47 +1.500.0020.0050.0051534322543229826.270__
196348___________ +1.27 +1.150.0030.0030.0311340817067153816.876__
*19260____________ +1.44 +1.650.0000.0010.0003501950279579496.1455_delta8-sphingolipiddesaturase
19250____________ +1.28 +1.230.0020.0030.0101512119401186026.1992_fattyacyltransferase
194125___________ +1.19 +1.100.0110.0110.0621411616831155436.2513_
191702___________ +1.13 +1.080.0180.0130.1531307114719141196.3043_GTP-bindingADP-ribosylationfactor
194699___________ +1.26 +1.100.0050.0040.0851339816883147136.3521_
194747___________ +1.18 +1.120.0100.0100.0621569418465175356.4017_mitochondrialprotoporphyrinogenoxidase
*192828___________ -1.23 -1.090.0130.0090.1534719238414432696.4489_alpha-tubulinfoldin,cofactorB
193479___________ +1.09 +1.030.4690.8850.2591892120669195746.4980_hypotheticalprotein
196297___________ +1.12 +1.170.0110.0370.0171667518688194496.5447_pseudouridinesynthase|rRNAmethyltransferase
1930_____________ -1.00 +1.001.0000.9950.9981707417003171556.5924_P-typeATPase,S.cerevisiaehomologisnecessaryforsensitivitytoakillertoxin(SMKtoxin)producedbyPichiaFarinosa
*191422___________ +1.38 +1.310.0010.0020.0023381346719443496.6392_
194089___________ -1.13 -1.060.2960.1530.6604805042600453426.6847_subunitofSCFubiquitinligasecomplex|regulatorofcellcycle
19889____________ +1.10 +1.120.0170.0210.0581801019821202256.7288_thiaminebiosynthesis|phosphomethylpyrimidinekinase
196988___________ +1.11 +1.100.0150.0150.0761254213895137576.7734_oligosaccharyltransferase|involvedinglycosylationintheERlumen
19936____________ +1.03 -1.010.3900.4180.3051511415622149126.8185_sphingomyelinphosphodiesterase
*197454___________ +1.15 +1.230.0120.0730.0132733131406335846.8614_TATA-bindingprotein-associated-factor|TFIIDandSAGAsubunit
195974___________ +1.13 +1.220.0060.0120.0191371115451166886.9063_requiredforstarvation-inducedautophagy
194549___________ +1.04 -1.020.4900.2690.8052258423406220976.95___
*195765___________ +1.39 +1.330.0040.0090.0111643722769218396.586__
191124___________ +1.05 -1.020.1760.0790.7672021621185197676.1199_phytanoyl-CoAdioxygenase(PhyH)
193151___________ +1.13 +1.060.0530.0350.2271320214895140276.1741_similartoplantdihydroflavonol4-reductase
*193951___________ -1.13 -1.360.0030.0280.0034923843656362056.2274_
194341___________ +1.04 +1.080.0760.0970.1121221812653131616.2798_cell-divisioncycle
194919___________ +1.30 +1.200.0060.0070.0331309416991156516.3298_transposase
195724___________ +1.09 +1.070.0460.0360.1621232313390131256.3795_
192223___________ +1.16 +1.120.0180.0240.0521568118199175266.4268_TNFreceptorassociatedfactor
192105___________ +1.19 +1.150.0500.0250.4581380016437159116.4756_zincfingerprotein
*194148___________ +1.32 +1.140.0080.0100.0462619534536298656.5231_hypotheticalprotein
192985___________ +1.02 +1.030.5400.4270.4961375013969141966.5704_hypotheticalprotein
195821___________ +1.02 +1.060.3100.2570.3421252612773132176.6157_conservedhypotheticalprotein
66634____________ +1.06 +1.090.1260.2860.0932354024912257196.6634_
19490____________ -1.01 -1.060.2680.6150.1492331223082219886.7081_peptideN-acetyltransferase
193838___________ +1.04 -1.030.6520.6380.4781119281165931090976.7533_translationelongationfactoreEF1beta|GDP/GTPexchangefactorforTef1p/Tef2p
195034___________ +1.13 +1.050.0530.0410.1822494528181261766.7975_conservedhypotheticalprotein
197337___________ +1.12 +1.050.0380.0210.3281297114468135916.8419_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*196778___________ +1.36 +1.330.0060.0110.0191556621102206516.8853_membrane-spanningCa-ATPase(P-type)
42343____________ +1.07 +1.010.5330.2880.9711204012932121374.2343_
*19361____________ -5.41 -5.410.0010.0020.0028574215856158386.285__mitochondrialcarnitineacetyltransferase
*196240___________ +1.39 +1.330.0020.0040.0081573221906209796.904__
*194793___________ +1.38 +1.310.0010.0040.0051776424600233276.1470_
191049___________ +1.45 +1.280.0010.0020.0061298518826165666.2005_
*191783___________ +1.88 +1.690.0010.0040.0041398726288236656.2531_oligomycinresistanceATP-dependentpermease|ABCtransporter
*194796___________ +1.32 +1.210.0030.0050.0192114327933256766.3056_
191504___________ +1.25 +1.150.0050.0100.0151388017319159126.3539_
195098___________ -1.28 -1.420.0010.0050.0032625420564184916.4033_endonucleaseIII-likeglycosylase
*195634___________ +1.76 +1.640.0000.0010.0013224856672527496.4503_ferricreductase
194517___________ +1.08 +1.060.1840.1190.3702662428754282196.4994_conservedhypotheticalmembraneprotein
*194676___________ -1.73 -1.820.0010.0040.0023609420862198686.5460_conservedhypotheticalprotein
19206____________ +1.22 +1.200.0060.0100.0201317416072157956.5939_
191547___________ +1.16 +1.070.0170.0150.0951621518733173936.6405_ThreePrimePhosphatase1|DNA3'phosphatase|similaritytomammalianpolynucleotidekinase3'-phosphatase
196710___________ +1.15 +1.120.0320.0380.0832246625923251216.6859_hypotheticalprotein
19875____________ -1.18 -1.180.0020.0060.0072697822833228226.7302_hypotheticalprotein
*197001___________ +1.45 +1.310.0020.0040.0081752425460229406.7746_
19948____________ +1.18 +1.070.0190.0140.1601306115414139466.8197_hypotheticalprotein
*195391___________ +1.39 +1.520.0000.0020.0012053628634311946.8627_snRNAbindingprotein
*195962___________ +1.41 +1.290.0010.0020.0102645637181341146.9075_highaffinityglucosetransportprotein
195844___________ +1.47 +1.270.0010.0020.0101306519230165886.114__
193535___________ +1.32 +1.210.0010.0040.0061566420607190316.605__
191353___________ +1.44 +1.340.0010.0020.0071467921200197246.1217_hypotheticalprotein
*193223___________ -4.34 -5.100.0000.0000.00038367188493752866.1763_ATPsynthasegammasubunit
*193774___________ +1.63 +1.490.0010.0010.0031565725484233746.2291_serine/threonineproteinphosphatasetype2A
194407___________ +1.27 +1.220.0070.0090.0341305216640158626.2821_
*195036___________ +1.68 +1.520.0010.0020.0041758629559267886.3313_conservedhypotheticalprotein
192559___________ -1.19 -1.060.1240.0760.3449577680527901976.3808_Fboxprotein,forubiquitin-dependentdegradation
*193536___________ +1.33 +1.300.0020.0070.0052108327982274216.4282_alphaN-acetylglucosaminetransferase
192375___________ +1.21 +1.290.3520.7570.1902220626865285506.4773_retrotransposongagprotein
193861___________ -1.09 -1.130.0530.0590.1073857035283341246.5250_
*192971___________ +1.28 +1.310.0010.0040.0032266228980297656.5718_conservedhypotheticalprotein
192492___________ +1.13 +1.150.0150.0320.0291423716124163936.6171_
*192966___________ -1.14 -1.080.0150.0150.0709134179850843726.6650_putativecarboxymethylenebutenolidase
*191477___________ -1.64 -1.970.0000.0020.0017986848576404966.7096_conservedhypotheticalprotein
196562___________ +1.09 +1.110.6820.7270.4711342314660149256.7550_ribonucleaseH
*195021___________ +1.33 +1.610.0040.0340.0051469119528236626.7988_pyruvatedehydrogenasecomplexproteinX
*197121___________ -1.41 -1.120.0360.0280.153112998802891009126.8432_hypotheticalprotein
196763___________ +1.06 +1.100.2740.4180.1893442536433379706.8866_
42597____________ +1.02 +1.030.3730.2880.4061209612358124244.2597_
196261___________ +1.33 +1.150.0030.0040.0301292017225148726.300__
191297___________ +1.24 +1.160.0040.0050.0221274415855147786.924__cytoplasmtovacuoletargeting
194646___________ +1.34 +1.230.0030.0040.0211451419404179206.1489_hypotheticalprotein
194461___________ +1.28 +1.090.0060.0050.0881250215959136806.2028_hypotheticalprotein
19804____________ +1.07 +1.040.1660.0840.5421603617209166206.2547_mitochondrialADP/ATPcarrierprotein|Grave'sdiseasecarrierprotein
193797___________ -1.03 -1.030.2220.1560.3561648816068160106.3070_
19856____________ +1.29 +1.200.0020.0030.0161486119161178236.3556_
193928___________ +1.25 +1.100.0070.0060.1231231415389135636.4049_
195647___________ -1.18 -1.230.0050.0150.0092470820954200386.4516_RNAhelicase
*194212___________ +3.06 +4.250.0000.0000.000379391159131614006.5009_multicopperferro-O2-oxidoreductaseinvolvedinhigh-affinityironuptake
*193744___________ +1.45 +1.410.0020.0050.0061834426552259566.5475_
195142___________ +1.09 +1.060.0870.0480.3771506016417159476.5956_dihydrofolatereductase
*191562___________ +1.47 +1.570.0020.0040.0051755625799275446.6419_hypotheticalprotein
*196725___________ -5.01 -6.390.0000.0010.00111063822073173056.6874_mitochondrialfumaratehydratase,3-primeend
196929___________ +1.08 +1.030.1340.0750.4121270613778130876.7315_conservedhypotheticalprotein
193023___________ +1.15 +1.050.0730.0320.6731465016883153216.7760_transcriptionfactor
*19962____________ +1.19 +1.200.0070.0150.0191583218806190316.8212_
*195407___________ +1.84 +2.360.0000.0020.0012039037476482016.8643_nucleolarsnRNPprotein
195947___________ +1.08 +1.140.0230.0380.0481418015377161196.9091_
19206____________ +1.26 +1.220.0030.0090.0071337216787163616.129__
*196891___________ +1.36 +1.290.0030.0070.0132039327754262476.632__
*193167___________ -1.22 -1.270.0170.0700.0212914023862228556.1237_
*192842___________ +1.87 +1.670.0010.0030.0041657730949276836.1777_
193848___________ +1.19 +1.110.0230.0150.1751246114865138866.2311_
194967___________ +1.07 +1.010.2140.1150.5311350814456137006.2838_proteinrequiredforcytochromecoxidaseactivity
*19702____________ +1.11 +1.160.0380.0600.0642563028325297016.3326_DNAhelicase
192640___________ +1.14 +1.130.0450.0920.0561603218289181916.3823_uracilphosphoribosyltransferase
19299____________ +1.24 +1.090.0580.0440.1841978524474215076.4294_carboxypeptidaseinvolvedincellwallbiogenesisandarchitecture
*195629___________ -1.31 -1.710.0020.0190.0027256755276425246.4788_ubiquinolcytochrome-creductasesubunit7
196550___________ -1.07 -1.130.0150.0940.0152351721938208616.5264_conservedhypotheticalprotein
191264___________ +1.07 +1.060.3880.2980.4181366414569144946.5731_ferricreductase
195768___________ -1.07 -1.080.1100.4250.0652994927964278566.6189_
*192954___________ -1.94 -2.640.0000.0010.00012139562440459766.6662_hypotheticalprotein
191462___________ +1.18 +1.160.0200.0220.0681338215731155706.7110_
196578___________ -1.38 -1.400.0300.0450.0622429417551174126.7566_inorganicphosphatetransporter,transmembraneprotein
195007___________ +1.09 -1.050.7690.5270.8232994232778285196.8001_
*197108___________ +1.25 +1.230.0160.0240.0427342092126902446.8445_D-ribulose-5-phosphate3-epimerase
196751___________ +1.04 +1.060.4290.8230.2352769528786294546.8880_tRNAmethyltransferase
42768f++3________ +1.08 +1.060.5640.3160.8891232113299130604.2768f
*193599___________ +1.53 +1.370.0010.0020.0062883344060395676.314__
19153____________ +1.28 +1.280.0090.0140.0291292816518165996.942__
*191133___________ +1.68 +1.440.0010.0030.0091842430908265416.1505_
193585___________ +1.41 +1.210.0020.0040.0151414719941171676.2043_conservedproteinrequiredforviabilityinbuddingyeast
19113____________ +1.33 +1.300.0030.0070.0101324817660172366.2563_
*191212___________ +1.79 +1.820.0000.0010.0025044890400917316.3084_
*192269___________ -2.65 -2.530.0000.0000.0004265241608611686336.3572_3-phosphoserinephosphatase
194674___________ +1.56 +1.250.0010.0030.0101411321962175786.4062_hypotheticalprotein
*194370___________ +1.83 +1.630.0000.0000.0004538483023740016.4535_conservedhypotheticalprotein
*193331___________ +2.76 +2.980.0000.0010.0011755748445523596.5023_
192701___________ +1.01 +1.000.9590.8340.8811726917494173076.5489_hypotheticalprotein
192029___________ +1.03 -1.010.4160.3090.4502533425978249886.5968_DNAreplicationnfactorC|leadingstrandelongationmismatchrepair(ATPase)
*191639___________ +1.49 +1.650.0020.0060.0051323419771217736.6433_
*195648___________ -1.69 -1.730.0000.0020.0025065129968292216.6888_
67329____________ +1.05 +1.120.2580.2660.2494247044529474716.7329_
*193038___________ +6.54 +7.840.0000.0000.000247441618061938846.7776_
19978____________ +1.30 +1.230.0080.0100.0391425718546174756.8227_transcriptionfactor
*195420___________ -2.09 -2.080.0000.0000.0007153434244344466.8657_
*195932___________ +1.57 +1.470.0000.0010.0002768743443407116.9105_conservedhypotheticalmembraneprotein
19160____________ +1.31 +1.270.0010.0030.0071268116592160966.145__hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194194___________ -1.04 -1.010.3220.2070.4752775726634275216.651__
191859___________ +1.26 +1.120.0080.0080.0591264215903142146.1255_hypotheticalprotein
197680___________ +1.03 +1.130.2860.2590.29895306985201079496.1797_
192504___________ +1.27 +1.180.0070.0090.0361268716108149216.2327_GTP-bindingproteininvolvedin40Sribosomebiogenesis
19460____________ +1.11 +1.070.0120.0110.0761259013997134376.2854_serine/threonineproteinkinaseofMAPkinasefamily|Requiredformating
*193334___________ -3.09 -2.430.0000.0000.0004811801558131982306.3341_ribosomalprotein
194880___________ +1.19 +1.160.5420.8200.3221247214835144186.3839_
*194477___________ -1.57 -1.170.0010.0010.0301958011250161672556.4310_aryl-alcoholdehydrogenase
19278____________ +1.13 +1.090.0270.0230.1141941321985211706.4807_neutralaminoacidtransportsystemprotein
193012___________ +1.09 +1.060.0780.0500.2711230813472131076.5277_
*191668___________ +1.30 +1.380.0010.0030.0012302029995316676.5743_hypotheticalprotein
*196594___________ +1.45 +1.470.0030.0080.0113536751109521466.6205_
194529___________ +1.01 +1.060.3650.6030.2192482824997264186.6675_conservedhypotheticalprotein
*191448___________ +2.17 +2.420.0000.0000.000536841165071301796.7125_adeninephosphoribosyltransferase
*196034___________ +3.43 +3.860.0000.0000.000366381257371414446.7578_beta-tubulin
*194993___________ +1.35 +1.690.0040.0230.0061576621346265896.8016_
*197095___________ +1.70 +1.840.0000.0010.0003802264734699276.8458_conservedhypotheticalmembraneprotein
*197546___________ +1.45 +1.780.0000.0030.0002284633041407106.8894_ATPdependentRNAhelicase
42857____________ +1.08 +1.040.0980.0600.3201189412874123524.2857_
19381____________ +1.19 +1.080.0070.0060.0721232714678132866.334__hypotheticalprotein
*191331___________ +1.73 +1.550.0020.0030.0081458525184226136.958__
*195066___________ +1.53 +1.420.0020.0030.0071407221474199226.1521_conservedhypotheticalprotein
*19367____________ +1.93 +1.950.0000.0000.0002487147916485126.2058_
*193369___________ +3.94 +3.940.0000.0000.0002015279452794626.2579_
194567___________ +1.28 +1.120.0040.0060.0191368117568152716.3099_hydroxyquinol1,2-dioxygenase
*192755___________ +1.68 +1.690.0000.0000.0002546642809429776.3587_proteasomesubunit
192363___________ +1.16 +1.400.1110.5220.0614439451466623256.4077_putativeheatshockprotein
*1957_____________ +1.54 +1.450.0010.0020.0021827628124264866.4549_subunitofGINScomplexrequiredforchromosomalDNAreplication
191968___________ +1.18 +1.170.0720.0510.2241791921066210176.5036_hypotheticalprotein
*196314___________ +1.31 +1.410.0010.0050.0031685422163236806.5507_16-kDaRNApolymerasesubunit(commontopolymerasesI,IIandIII)
*192043___________ +1.25 +1.430.0000.0020.0011762521985251186.5982_conservednucleotidebindingprotein
*191625___________ -2.49 -2.350.0000.0000.0008846935549376446.6447_oxidoreductase
195662___________ +1.05 +1.080.0830.0970.1271801318856193796.6902_vacuolarsegregationprotein
1948611__________ -1.06 +1.000.4650.2400.9503006728437301746.7350_NA
*193051___________ -1.53 -1.360.0000.0010.0033760824566276866.7788_conservedhypotheticalprotein
*193240___________ +1.09 +1.160.0090.0440.0132209024130256376.8240_3-ketosterolreductase
195433___________ -1.32 -1.240.0020.0040.0132349217852189046.8669_conservedhypotheticalprotein
195918___________ +1.10 +1.070.0250.0140.2931359214912145006.9119_hypotheticalprotein
*19723____________ +1.66 +1.730.0020.0080.0061501424960260016.6____
196244___________ +1.18 +1.090.0120.0120.0631959223097213476.672__
19244____________ +1.10 +1.100.1760.2870.1401607217756176276.1271_involvedinnitrogen-catabolitemetabolism
193456___________ +1.13 +1.070.0180.0180.0771668318857179296.1815_proteinserine/threoninekinaseinvolvedincellwall/polarity
*193895___________ +1.47 +1.350.0030.0050.0152996444132405996.2343_
191767___________ +1.01 +1.020.3540.1760.8151211212227124106.2870_ubiquitincarboxyl-terminalhydrolase
196493___________ +1.16 +1.080.0170.0180.0701235714328133586.3358_conservedhypotheticalprotein
19842____________ -1.09 -1.220.0510.6290.0266065455547497666.3853_hypotheticalprotein
193406___________ +1.08 +1.060.1920.1680.2562057122259217166.4325_highlyconservedhypotheticalprotein
*19609____________ +2.09 +1.790.0000.0010.0024651997134830916.4822_
*191358___________ -1.22 -1.410.0090.1390.0072217661819391571886.5290_transcriptionalactivatoroftheaastarvationresponse
193572___________ +1.08 +1.050.0440.0380.1411587517187166466.5757_hypotheticalprotein
196607___________ +1.14 +1.010.2800.1360.7383211236512325826.6219_NADH-ubiquinoneoxidoreductase|NADHdehydrogenasesubunit
*194540___________ +4.33 +3.250.0000.0000.00027786120222902766.6687_
*196874___________ +2.50 +2.390.0000.0010.0002690867271642176.7138_myb-liketranscriptionfactor
*196047___________ -8.77 -11.590.0000.0000.00044862351141386946.7591_mitochondrialtranslationelongationfactorTU
*197136___________ +1.48 +1.640.0020.0050.0051829427084300226.8032_
*197081___________ +2.49 +2.510.0000.0000.0002111352649529806.8472_tRNAsplicingprotein
197558___________ +1.11 +1.210.0100.0220.0231305214465158556.8907_
43057____________ +1.05 +1.060.0620.0380.2761316613779139144.3057_
*19462____________ +1.91 +2.490.0000.0010.0002477647397618036.352__mitochondrialmembraneexonucleaseinvolvedinpre-rRNAprocessing
191349___________ +1.26 +1.180.0050.0100.0171540619364182096.980__hypotheticalprotein
192868___________ -1.05 -1.090.0630.2780.0431180111216108656.1536_hypotheticalprotein
*191383___________ +1.44 +1.300.0010.0030.0071695024457219946.2081_hypotheticalprotein
193770___________ +1.17 +1.110.0130.0140.0651287515124143166.2597_
*191710___________ -1.60 -1.640.0010.0040.0044965430981303676.3117_mitochondrialNADH-ubiquinoneoxidoreductase
192785___________ -1.12 -1.180.0870.1710.0832948826293249296.3602_ATPsynthasedsubunit
*191759___________ +1.16 +1.160.0060.0140.0183191437055369446.4090_transcriptionalregulator
*195684___________ -5.13 -4.620.0000.0000.00039012176035845246.4562_mitochondrialribosomalproteinL14
*195858___________ -3.75 -4.140.0000.0000.00023833463497576376.5050_GAL4enhancerprotein
196328___________ +1.05 +1.010.3570.1960.6451643817249166676.5521_conservedhypotheticalprotein
196461___________ +1.06 +1.020.2210.1250.4891522816159155656.5998_cytochromeoxidase
*193443___________ +1.55 +1.670.0010.0020.0022201534224368506.6462_NAPDHdehydrogenase(oldyellowenzyme)
195676___________ +1.11 +1.100.0780.0930.1224113845520452656.6916_conservedhypotheticalprotein
*194847___________ +1.14 +1.180.0130.0340.0232749631413324876.7364_
*193063___________ +1.21 +1.110.0110.0110.0662998736272331946.7800_DNA-directedDNApolymeraseepsilon,subunitC
*193252___________ +1.37 +1.460.0010.0040.0022140929258313596.8252_transcriptionalactivatorforallantoinandGABAcatabolicgenes
*195446___________ -27.22 -20.150.0000.0000.000175179064347869496.8682_hypotheticalprotein
*195905___________ +1.48 +1.440.0090.0130.0341329019693191776.9132_nucleolarproteininvolvedinmating-typeregulation
195126___________ +1.00 -1.010.8530.8760.6332671026835264996.37___
194862___________ +1.38 +1.210.0010.0020.0051488420529180266.689__conservedhypotheticalprotein
196224___________ +1.32 +1.160.0030.0040.0321303517258150956.1289_conservedhypotheticalprotein
193726___________ +1.42 +1.260.0190.0140.1461310818668164636.1834_
19262____________ +1.34 +1.260.0020.0040.0121281517155160896.2357_
193370___________ +1.19 +1.180.0080.0170.0201301815487153036.2890_ubiquitin-specificprotease
*192524___________ -2.55 -2.200.0000.0010.0027797030618353736.3373_chaperoneinvolvedinproteinimportintomitochondria
192381___________ +1.29 +1.230.0020.0030.0101575120291193006.3867_
*192202___________ +1.17 +1.340.0030.0130.0061026701206071377326.4339_phosphoglyceratemutase
*191723___________ +5.29 +5.820.0000.0000.000271941439891581486.4837_conservedhypotheticalprotein
*193706___________ -1.21 -1.420.0030.0140.0043674230370258606.5304_
196342___________ +1.17 +1.150.0160.0240.0441296815112149756.5771_microfibrillar-associatedprotein1|associatedmicrofibrilprotein
196105___________ -1.13 +1.010.2210.1020.7588098171876819226.6237_
19811____________ +1.05 +1.010.6600.4020.8631817019040184276.6702_conservedhypotheticalprotein
*67151____________ -3.83 -3.400.0000.0000.00032188284039945796.7151_
196060___________ +1.16 +1.110.0180.0190.0761269814679141306.7604_ATP-bindingcassette(ABC)family,regulatoroftranslationalelongation
*197149___________ +1.61 +1.940.0010.0060.0031618126031314626.8049_conservedhypotheticalprotein
*197067___________ +1.82 +1.690.0000.0020.0012498945438422806.8486_requiredfornormalCLN1andCLN2G1cyclinexpression
*197572___________ +1.52 +1.460.0040.0080.0111396821199204536.8921_
43071____________ +1.16 +1.240.0110.0380.0171348815710166664.3071_
*19566____________ +1.58 +1.280.0120.0080.1871244319633159436.370__hypotheticalprotein
193868___________ +1.25 +1.230.0040.0080.0141315116439161426.1003_hypotheticalprotein
*193962___________ +1.66 +1.520.0000.0010.0021985133004300856.1552_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
193409___________ +1.24 +1.140.0110.0130.0541368216937155356.2099_
194129___________ +1.26 +1.230.0050.0080.0191286916245158676.2618_hypotheticalprotein
191158___________ -1.24 -1.240.0100.0170.0292543120550204876.3133_hypotheticalprotein
*192438___________ -1.40 -1.540.0010.0040.0033397224252220406.3616_conservedhypotheticalprotein
*192591___________ +1.53 +1.390.0010.0010.0051762826999244436.4107_DAPAaminotransferase
195700___________ +1.04 -1.070.2860.6810.1544017441763376796.4578_transcriptionalactivatorCTA2
*195609___________ +1.28 +1.220.0030.0070.0102757335341335076.5063_hypotheticalprotein
*192311___________ -1.92 -1.760.0000.0000.00016438085662934506.5539_ribosomalproteinL8B
19733____________ +1.06 +1.390.0630.9840.0303296333497844573716.6010_conservedhypotheticalprotein
*193664___________ -78.86 -82.080.0000.0000.000193812624578236146.6475_membraneheatshockprotein
193117___________ +1.32 +1.140.0090.0090.0671539220376176186.6927_
194831___________ -1.10 -1.060.1280.0670.4652077818912196236.7379_
*196442___________ +1.45 +1.320.0060.0080.0331417020537186986.7813_
193266___________ +1.18 +1.240.0010.0070.0031862621987230686.8266_hypotheticalprotein
195461___________ -1.13 +1.040.8350.6760.7271253911106351298256.8697_hypotheticalprotein
195892___________ +1.17 +1.130.0260.0260.0921276014906144506.9146_
191744___________ +1.25 +1.270.0050.0110.0141493418675189446.69___
*194867___________ +2.99 +2.690.0000.0020.0021698250735457056.706__
195757___________ +1.15 +1.090.0080.0080.0561284214789139466.1304_conservedhypotheticalprotein
*193142___________ +1.47 +1.200.0010.0010.0132258433161270086.1853_conservedhypotheticalprotein
*194635___________ +1.86 +2.060.0020.0060.0051342625015276866.2373_
19168____________ +1.14 +1.120.0300.0320.0901380715696154796.2904_exosomeexoribonucleaserelatedtoRNAprocessingandtransport
195050___________ +1.14 +1.100.0230.0210.1081234914126135436.3386_MitochondrialTranslationOptimization
*193683___________ +1.40 +1.290.0030.0050.0141923626912248946.3883_Znfinger-containingGTPase-ActivatingProteinforARF
*195504___________ +2.27 +1.750.0000.0000.0004184294988732246.4352_hypotheticalprotein
*195777___________ +1.18 +1.260.0160.0300.0342066124361260856.4849_involvedinpseudohyphalgrowth,resistancetoNaClandH2O2
*196155___________ +1.66 +1.500.0010.0020.0042345438897352026.5316_DNAligase
196357___________ -1.10 -1.090.0730.1010.1021170410687107786.5786_coiled-coilproteininvolvedinthespindle-assemblycheckpoint
*196091___________ +1.46 +1.040.0010.0000.15976097110875791406.6250_pHresponseregulator
*19827____________ -1.23 -1.450.0000.0060.0003361127248231656.6718_hypotheticalprotein
*196903___________ +1.26 +1.220.0020.0050.0102190527684266496.7167_RNApolymeraseIIIsubunit
*196073___________ +7.96 +5.460.0000.0000.000310992476371697436.7617_hemebindingprotein
197161___________ +1.10 +1.060.1200.0600.5023246835667343356.8061_betasubunitoftranslationinitiationfactoreIF-2
197055___________ +1.01 +1.010.2560.1560.4591302813158131896.8498_hypotheticalprotein
197589___________ +1.01 -1.070.3190.7160.1731893219094176646.8937_hypotheticalprotein
19619____________ +1.34 +1.270.0020.0050.0121262616877160496.386__hypotheticalprotein
191431___________ +1.19 +1.130.0110.0140.0461239014756140396.1025_allantoatepermease
196250___________ -1.16 -1.080.2770.3120.2395254245344486956.1567_
*197414___________ -1.26 -1.310.0010.0020.0023715529424283156.2110_
*62632____________ +2.09 +2.450.0000.0000.0002691256201658736.2632_
*194979___________ +1.59 +1.550.0040.0070.0141421822632220646.3147_
*19753____________ +1.73 +1.830.0000.0010.0002025834971370686.3632_mannosyltransferase
*195552___________ +2.32 +2.070.0000.0010.0012302853393475696.4122_hypotheticalprotein
*194760___________ +1.84 +1.950.0000.0020.0011931135517376676.4595_
*191238___________ +1.80 +1.530.0000.0010.0022029536586311046.5079_
*192680___________ +2.45 +2.180.0000.0010.0011724842289375506.5555_
*196264___________ -1.10 -1.170.0100.1910.0082582223458220316.6023_hypotheticalprotein
*193677___________ +1.31 +1.250.0010.0030.0113669448119459976.6488_involvedinautophagyandnutrientstarvation
193103___________ +1.11 +1.100.2300.1940.2891197251331651317356.6942_RNApolymeraseIIIlargesubunit
*196960___________ +2.72 +2.820.0000.0010.0011782048501502106.7392_
*196425___________ +1.57 +1.880.0020.0090.0051379221620258756.7828_
*193280___________ +1.46 +1.570.0010.0040.0042019929397317036.8280_hypotheticalprotein
197463___________ -1.10 -1.040.0830.0400.5051887817186181136.8713_
195875___________ +1.11 +1.050.0800.0530.2601315614618138046.9162_t-SNARE|integralmembraneproteinlocatedinendosome
195607___________ +1.49 +1.360.0020.0040.0091535622842208746.93___
195617___________ +1.36 +1.250.0010.0020.0061271017231158866.723__
192226___________ +1.32 +1.220.0020.0030.0131382918273168696.1319_hypotheticalprotein
*193802___________ +1.72 +1.500.0030.0060.0111271421893190646.1865_
192531___________ -1.20 +1.050.0950.0400.8815229043659549056.2388_cellsurfaceprotein
195742___________ +1.24 +1.220.0050.0130.0131256915624153426.2921_
*195126___________ +1.23 +1.120.0410.1010.0471796022165200676.3405_
19417____________ +1.20 +1.130.0080.0120.0331296415617146716.3898_membranetransporter,MitochondrialCarrierFamily
193505___________ +1.20 +1.140.3020.2710.3101189641428041352806.4365_putativetranscriptionfactor
*192998___________ +1.58 +1.530.0000.0010.0012968246843453966.4868_
*196168___________ +1.65 +1.900.0010.0030.0021851430594352636.5329_conservedhypotheticalprotein
*19997____________ +1.52 +1.430.0000.0010.0012292834954327986.5801_hypotheticalprotein
*19398____________ +1.45 +1.720.0000.0000.0003170146075544296.6266_hypotheticalprotein
*19518____________ +1.24 +1.310.0060.0290.008978911216791278766.6730_tRNA:m5C-methyltransferase
196916___________ -1.75 -1.580.0010.0020.0032846016242180196.7180_F1F0-ATPasecomplexassemblyprotein
196530___________ +1.17 +1.140.0080.0130.0281696219894193616.7630_conservedhypotheticalprotein
*197177___________ +1.79 +1.400.0100.0120.0481379624657192906.8077_karyopherin|nucleartransportfactor
*197350___________ -2.97 -2.950.0000.0000.0007916442666732687736.8510_highlychargedconservedproteinofunknownfunction
*197601___________ +1.12 +1.220.0040.1050.0032444427421297416.8949_conservedhypotheticalprotein
19121____________ +1.55 +1.290.0030.0040.0201278419789164826.406__subunitoftheArp2/3complex
*195865___________ +1.53 +1.440.0010.0020.0031722726423247376.1040_
191808___________ +1.29 +1.150.0050.0060.0371218115746140566.1582_hypotheticalprotein
191048___________ +1.29 +1.270.0050.0100.0161231415824156276.2130_conservedaryl-alcoholdehydrogenase
192627___________ +1.28 +1.180.0040.0070.0201310816803154296.2647_hypotheticalprotein
194312___________ +1.28 +1.200.0050.0080.0191359017458163276.3166_
194187___________ +1.36 +1.210.0030.0050.0151347418391162976.3644_mitochondrialoutermembraneproteininvolvedinmaintainingmitochondrialshape
*19747____________ +1.35 +1.340.0000.0010.0012323931391311446.4136_nuclearATPase
*194306___________ +1.13 +1.180.0140.0800.0153872243798457796.4611_conservedhypotheticalprotein
196013___________ +1.20 +1.160.0060.0100.0251418017002164496.5093_interactswithtopoisomerase1
*192340___________ +1.54 +1.850.0000.0000.0004011861831743786.5570_
196276___________ +1.12 +1.070.0210.0230.0741388215610148596.6035_conservedhypotheticalprotein
*19432____________ -1.52 -1.280.0000.0010.0084112327142320216.6501_conservedhypotheticalprotein
*195178___________ +1.69 +2.140.0000.0000.000716391207911531936.6958_cytochromeP450
193996___________ -1.00 +1.080.1940.6920.1002866428583309386.7409_glycosylphosphatidylinositol(GPI)synthesis
*196408___________ +1.40 +1.280.0090.0130.0341513821213193786.7845_
*195305___________ -2.08 -2.150.0010.0040.0059921047675461096.8294_conservedproteinreressedinhyphaldevelopment
*197478___________ -2.57 -2.300.0000.0000.0008365032535362956.8730_hexaprenylpyrophosphatesynthetase
193371___________ +1.23 +1.150.0080.0090.0511294615917148536.140__
195520___________ +1.17 +1.120.0130.0110.1011290015121144466.743__
191610___________ +1.18 +1.130.0080.0130.0261247214658141436.1339_hypotheticalprotein
193200___________ +1.25 +1.100.0100.0070.1241315816395144816.1883_matinglocusregulatoryprotein
194818___________ +1.23 +1.150.0130.0250.0291425817595163916.2401_hypotheticalprotein
193375___________ +1.11 +1.060.0980.0610.3051253013891132646.2937_
192184___________ +1.19 +1.120.0050.0060.0361594719045178326.3420_
192505___________ +1.15 +1.130.0100.0170.0301258014510142096.3910_hypotheticalprotein
*191798___________ +1.36 +1.460.0040.0080.0131563821272228696.4377_conservedhypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
191321___________ +1.08 +1.090.0340.0440.0751268613677138506.4882_
191580___________ +1.07 +1.140.0110.0230.0271621817359185436.5341_
196365___________ +1.01 -1.020.5310.2870.9771647216687161846.5817_phosphotyrosine-specificproteinphosphatase
19386____________ +1.16 +1.220.0060.0180.0131602618527195486.6278_AdoMet-homocysteinemethyltransferase
19533____________ +1.04 +1.050.1240.1110.2051307313637136906.6745_hypotheticalprotein
193297___________ -1.27 -1.360.0000.0030.0012351818579172586.7192_concervedhypotheticalprotein
196517___________ +1.01 -1.050.6010.6370.4211654516693158026.7644_
*1964031__________ -1.31 -1.740.0020.0190.0033953953027892267096.8088_NA
*197363___________ +1.33 +1.540.0060.0110.0181538920525237146.8523_glucansynthasesubunitinvolvedincellwallassembly
197614___________ +1.05 +1.060.1260.1000.2402416925313256536.8962_hypotheticalprotein
19625____________ +1.26 +1.280.0030.0060.0121261715888161586.422__
194697___________ +1.48 +1.290.0020.0030.0111388220609179656.1058_
195059___________ +1.18 +1.130.0190.0230.0581208414207136526.1607_
191077___________ +1.46 +1.300.0020.0040.0121428420882185226.2147_mitochondrialABCtransporter
191773___________ +1.28 +1.200.0030.0050.0131343917154161906.2661_
19268____________ +1.50 +1.440.0020.0050.0061431921484206726.3181_
19761____________ +1.29 +1.210.0020.0030.0101669621608201426.3661_hypotheticalprotein
*191690___________ +3.04 +2.820.0000.0000.0002622379723738836.4151_
*195701___________ +1.82 +1.830.0000.0010.0015225294920958016.4631_conservedhypotheticalprotein
196131___________ +1.05 -1.000.5840.3780.6771678217682167196.5112_3-ketosphinganinereductase
*192324___________ +1.44 +1.240.0010.0030.0072900541795359006.5584_ubiquitin(URM1)activatingenzyme
194942___________ +1.12 +1.080.0510.0360.2071264914159137116.6048_hypotheticalprotein
*19448____________ +2.65 +2.320.0000.0000.0012769473424643706.6517_
195165___________ +1.15 +1.100.0120.0170.0391611518503177626.6971_conservedhypotheticalprotein
*194009___________ +1.53 +1.380.0000.0010.0021770027130243556.7421_
196391___________ +1.08 +1.110.0490.0520.1131238413383137576.7863_hypotheticalprotein
195318___________ +1.39 +1.270.0040.0060.0221360618924173416.8308_
197490___________ +1.03 -1.010.5190.3430.6001839318875182116.8742_conservedhypotheticalprotein
192921___________ +1.21 +1.190.0080.0130.0261260515292149736.168__
19651____________ +1.31 +1.220.0040.0070.0191250916413152286.763__
19801____________ +1.47 +1.280.0030.0050.0131380620271176976.1354_
192827___________ +1.36 +1.220.0020.0030.0191407619074171556.1901_highlyconservedhypotheticalprotein,putativecytoskeletalcomponent
193950___________ +1.18 +1.130.0190.0180.0921415116754159596.2417_methionyl-tRNAsynthetase,mitochondrial
194488___________ +1.08 +1.070.1460.1480.1921262613589135436.2950_
191828___________ +1.25 +1.210.0040.0060.0181282615977155486.3435_involvedinbudsiteselection
196018___________ +1.18 +1.080.0100.0080.1091224514415132506.3923_
*193204___________ +1.75 +1.760.0000.0020.0012737447784480446.4395_hypotheticalprotein
194787___________ +1.24 +1.120.0090.0090.0551386017161155456.4897_DnaJ-likechaperone
191403___________ -1.11 -1.160.0110.0740.0122220220025191606.5356_calcium-bindingmitochondrialcarrier
196379___________ +1.09 +1.040.1100.0650.3551301014225134746.5831_hypotheticalprotein
195078___________ +1.19 +1.110.0980.0450.5982567230654284436.6298_hypotheticalprotein
19547____________ +1.10 +1.110.0360.0360.1051383415281153836.6758_
*193310___________ -1.27 -1.310.0250.1730.0205194040882397366.7205_hypotheticalprotein
196503___________ +1.16 +1.050.0450.0390.1421456916847153646.7657_hypotheticalprotein
*197202___________ +1.36 +1.180.0100.0080.1112063028088243006.8102_membraneproteinretentioninER
197375___________ -1.05 -1.010.4310.2740.5662292021809227226.8535_smallnuclearribonucleoprotein
197627___________ +1.01 +1.020.4160.2470.6161328413465134966.8975_conservedhypotheticalprotein
194863___________ +1.01 -1.020.6780.4180.8731184511966116036.442__
191592___________ +1.35 +1.230.0020.0040.0101291217444159216.1070_conservedhypotheticalprotein
194882___________ +1.29 +1.140.0050.0070.0251247816118142726.1624_
191272___________ +1.25 +1.160.0040.0060.0231298216243150276.2164_conservedhypotheticalprotein
191240___________ +1.26 +1.160.0050.0060.0381254915857145756.2677_
194119___________ +1.25 +1.130.0130.0120.0731261315794143136.3194_requiredforpexophagy
195219___________ +1.60 +1.300.0010.0020.0071493023946194166.3680_GTPaseactivatingprotein
191377___________ +1.21 +1.110.0130.0090.1771385616799153166.4163_dualspecificityinositol1,4,5-trisphosphate6-kinase|regulatorofarginine-responsivegenes
193551___________ +1.22 +1.110.0110.0150.0371305315905145196.4650_putativecytoskeletalprotein
*196229___________ -1.73 -1.790.0080.0170.0213150018170176416.5128_
191940___________ -1.09 -1.100.0620.2040.0502336521425212686.5599_mitochondrialproteininvolvedinubiquinonebiosynthesis
194167___________ -1.00 -1.020.9720.8580.9061277512735125566.6061_
196635___________ +1.34 +1.210.0060.0080.0271458619522176036.6532_hypootheticalprotein
66984____________ +1.20 +1.040.1040.0490.5491689620360175276.6984_
*194022___________ -2.47 -2.340.0000.0010.0015060020514215956.7435_membraneanchorinsuccinatedehydrogenasecomplex
194581___________ +1.11 +1.070.0490.0610.0911226413666130946.7880_mannosyltransferase
195328___________ -1.06 -1.060.1230.2390.1021248911821117636.8321_
197503___________ -1.02 -1.080.3900.5400.2552267122239210456.8755_chitindeacetylase
*193955___________ +1.64 +1.560.0000.0010.0022836946456441286.182__
194059___________ +1.23 +1.130.0040.0060.0271343916541152096.785__
1974_____________ +1.15 +1.100.0180.0160.0991250514420137036.1371_conservedhypotheticalprotein
*193931___________ -6.49 -7.920.0000.0010.00010677816444134886.1915_mitochondrialsuccinate-fumaratetransporter
195234___________ +1.33 +1.270.0030.0080.0071470019503187286.2435_
19193____________ +1.09 +1.150.0370.0780.0491277013916147056.2966_hypotheticalprotein
195206___________ +1.20 +1.120.0060.0090.0221596219123178716.3449_requiredforSnoRNAsoftheboxH/ACAQuantitativeaccumulation
195296___________ -1.28 -1.390.0010.0080.0022570620039184596.3938_conservedhypotheticalprotein
194044___________ +1.10 +1.000.0600.0260.7621710918763171276.4410_MuddledMeiosis
*195730___________ -1.35 -1.510.0010.0080.0025064637585336186.4909_3-polyprenyl-4-hydroxybenzoatedecarboxylase
192135___________ +1.21 +1.170.0160.0210.0541279415488150166.5370_
193879___________ +1.06 +1.090.0980.0990.1591193712654129646.5850_hypotheticalprotein
194392___________ +1.26 +1.200.0080.0090.0431538819400184796.6315_conservedhypotheticalprotein,mitochondrial
196665___________ +1.11 +1.200.0220.0490.0351777619804213916.6773_
*19335____________ +1.59 +1.400.0000.0010.0012355137358330776.7219_poorlyconservedhypotheticalprotein
195271___________ +1.14 +1.060.0280.0180.2161242414211131856.7670_
197214___________ +1.11 +1.160.0860.1850.0782895032113335906.8114_glucan1,3-beta-glucosidase
*197387___________ +1.68 +1.910.0010.0030.0011972633208377616.8547_ELongatorProtein|RNApolymeraseII-associatedHistoneacetyltransferase
*197643___________ -1.77 -1.920.0000.0000.0005589831560291466.8991_parahydroxybenzoate:polyprenyltransferase
19136____________ +1.41 +1.290.0510.1170.0561262917833162626.459__
191597___________ +1.29 +1.160.0030.0040.0311236015970143266.1085_hypotheticalprotein
193080___________ +1.09 +1.100.0710.0850.1171205013093132896.1637_
194730___________ +1.32 +1.220.0030.0050.0171494819734182586.2183_
193156___________ +1.34 +1.240.0030.0050.0211303417466161196.2692_
194072___________ +1.15 +1.090.0210.0180.1061260814478137396.3208_
*19685____________ -2.66 -2.580.0000.0000.0008650032572335626.3694_
195485___________ +1.10 +1.080.0250.0510.0402104723099226296.4179_involvedincheckpointcontrolandDNArepair|G2-specificcheckpointprotein
195492___________ +1.05 -1.030.4990.4780.3932441425525237236.4665_U1snRNPproteinrequiredforpre-mRNAsplicing
193905___________ +1.20 +1.100.0200.0210.0731273815312140596.5143_hypotheticalprotein
191850___________ +1.14 +1.130.0140.0180.0461266614465143166.5617_tyrosinephosphatase
194181___________ +1.05 +1.010.4170.2120.8791267713288127456.6075_subunitofsignalpeptidasecomplex
*196648___________ +2.07 +2.340.0010.0040.0021940640147454676.6544_
*196848___________ +1.58 +1.570.0000.0000.0003476654868545456.6997_vacuolarsortingprotein
*194035___________ -1.17 -1.620.0020.0790.0021695281445971048886.7448_GPIanchoredsurfaceprotein
194595___________ +1.09 +1.060.1190.0670.3901618017710170726.7894_hypotheticalmembraneprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
195348___________ +1.05 -1.020.1990.1390.3402398425276234896.8338_
*197517___________ +1.46 +1.430.0010.0040.0041437221012206016.8769_chitinase
193801___________ +1.24 +1.180.0240.0200.1201251115564147586.201__
193591___________ +1.19 +1.130.0120.0120.0721222814515138676.806__
191299___________ +1.35 +1.240.0030.0040.0171303917615161996.1388_proteasomeregulatoryparticlesubunit
*19554____________ +1.68 +1.770.0000.0010.0012071334752367646.1929_catalyzesoxidationofN-formyltyrosinetoN,N-bisformyldityrosineinsporewallformation
*194056___________ +2.19 +1.840.0000.0000.0003908285531718666.2451_GATA-familyDNAbindingproteins
*191108___________ +1.84 +1.950.0000.0000.0003112457218606416.2984_mayfunctioninDNArepair
*191111___________ +1.53 +1.630.0000.0010.00164124982301048416.3463_TFIIDandSAGAsubunit
*193765___________ +3.08 +3.170.0000.0000.0002261469680717976.3954_membraneproteininvolvedinbipolarbudding
*195587___________ -1.46 -1.410.0020.0040.0093544724215251506.4429_conservedhypotheticalprotein
*191066___________ +1.41 +1.370.0000.0010.0022015428366275586.4923_conservedhypotheticalprotein
*192151___________ -1.26 -1.340.0230.0500.0388468867198633626.5387_
*193129___________ -1.16 -1.250.0210.0540.0327377063737590816.5866_RUVB-likeprotein
*194351___________ -1.72 -1.130.0000.0000.047145988849371291846.6327_
*196680___________ -1.01 +1.110.0490.8620.0242854128394315486.6789_hypotheticalprotein
*19348____________ +1.34 +1.710.0010.0220.0011039861396361780436.7232_cellwallbeta-1,6glucansynthase
*195259___________ +1.21 +1.200.0100.0270.0183530042574424416.7683_hypotheticalprotein
*197228___________ +1.25 +1.280.0020.0100.0042629432843335976.8128_conservedhypotheticalprotein
*197399___________ +1.36 +1.740.0010.0070.0021662222554288446.8559_
197660___________ -1.05 +1.110.1100.5350.0602421623028269136.9008_suppressorofactinmutation
191570___________ +1.07 +1.130.2510.6930.1323879841346439536.480__
*191090___________ +1.75 +1.550.0010.0030.0021873732752289546.1102_hypotheticalprotein
*192616___________ +1.82 +1.620.0020.0050.0071452026360234606.1654_
196244___________ +1.48 +1.370.0010.0030.0041479321824202806.2196_
*193628___________ +2.73 +2.620.0010.0030.0031504941091393836.2711_hectdomainE3ubiquitin-proteinligase
191028___________ +1.13 +1.100.0150.0240.0391313814871144236.3223_transcriptionalelongationfactor
*196481___________ +1.32 +1.290.0100.0340.0152795036980359266.3713_GPI-anchoredaspartylprotease
*194502___________ +1.45 +1.300.0020.0040.0121592023088207146.4193_
192581___________ +1.08 +1.070.0790.0650.1891515616401161616.4682_putativedihydrokaempferol4-reductase
*19216____________ +1.54 +1.500.0000.0010.0012155833274322416.5157_conservedhypotheticalprotein
19326____________ -1.44 -1.350.0020.0040.0072569017794190256.5632_conservedhypotheticalprotein
*192175___________ -1.36 -1.240.0020.0020.0173645326867294256.6088_oxidoreductasesimilartomammalianApoptosisInducingFactor
*19668____________ +2.41 +2.210.0000.0010.0011650839704365406.6561_transcriptionfactortargetofSBF
196860___________ -1.03 +1.030.3880.2290.5973026229340312316.7009_phosphatidylinositolsynthase
*192093___________ +1.58 +1.710.0010.0030.002786761244331341526.7462_DNAreplicationfactorA|DNA-damagerepair
194609___________ +1.04 +1.010.2970.1440.7731197112499121126.7908_endo-1,3;1,4-beta-D-glucanase
*195365___________ +1.19 +1.320.0040.0220.0072402228536318146.8354_
*197534___________ +1.90 +1.910.0000.0010.0012145440679410526.8785_
19130____________ +1.19 +1.180.0040.0100.0091246914827147666.10___
1923181__________ +1.07 +1.120.0150.1120.0141252813427140536.503__NA
193956___________ +1.09 +1.060.0490.0810.0701249313561132706.1120_
194335___________ +1.00 +1.040.3830.9880.1991250812570129916.1676_
*196464___________ +1.56 +1.510.0010.0030.0022230734821336106.2212_
192712___________ -1.01 -1.020.7570.7490.5501183811664116156.2728_RNAhelicaseinvolvedinsnoRNAfunction
191728___________ +1.07 +1.040.1790.1170.3631214312987125836.3237_hypotheticalprotein
193091___________ +1.10 +1.050.1210.1280.1691319614562138596.3731_
192342___________ +1.07 +1.050.1670.2590.1421305514011136686.4210_similartomammaliansyntaxin5
192739___________ +1.06 +1.060.1130.1460.1351208412827128566.4695_
192419___________ +1.01 +1.020.8700.7570.7221270812834129806.5174_highlyconservedhypotheticalprotein
193971___________ +1.00 +1.020.9360.7830.8631201012036122296.5647_hypotheticalprotein
*193419___________ +2.28 +2.060.0000.0030.0014334198719894476.6106_mitochondrialmalatedehydrogenase
192774___________ +1.03 +1.030.3130.1700.6121235012661126636.6578_lipoicacidsynthase
191900___________ +1.12 +1.090.0910.1160.1221697419049185826.7020_TrimethylGuanosineSynthase
192078___________ +1.30 +1.230.0040.0100.0101462419045179446.7477_clathrin-coatprotein
194623___________ +1.15 +1.110.0170.0330.0341361315619151266.7922_hypotheticalprotein
197286___________ +1.01 +1.020.7400.5850.6491398014139141956.8367_subunitoftheregulatoryparticleoftheproteasome
196830___________ -1.11 -1.180.0210.0370.0431955217614166226.8801_enoylCoAhydratase
Cabgl98__________ -1.04 -1.050.2470.3350.193118261132311313Cabgl98
19229____________ +1.50 +1.350.0010.0030.0021448421673195376.216__
191652___________ +1.23 +1.190.0170.0290.0391610219744192106.828__
*19164____________ +1.48 +1.620.0010.0100.0021292919124209556.1404_
193515___________ +1.11 +1.090.1680.1970.1781739419339189856.1948_3-hydroxyanthranilicaciddioxygenase|biosynthesisofnicotinicacid
192154___________ -1.18 -1.100.3620.2340.4987444663244677866.2468_
*191097___________ +7.76 +5.690.0000.0010.00116396212716099324496.2999_
*19134____________ +1.66 +1.670.0030.0180.0052243537157373836.3480_hypotheticalprotein
194252___________ +1.06 +1.040.4200.6930.2451260413387130796.3972_predictedserine/threonineproteinkinase
*19307____________ +1.28 +1.410.0130.0810.0142733134852384356.4445_Ada/Gcn5proteincomplexmember
*192844___________ +1.79 +1.810.0000.0020.0011828632696331376.4939_
196184___________ +1.02 +1.000.3440.9520.1761526315564152726.5405_hypotheticalprotein
1983_____________ +1.30 +1.240.3880.4340.2954429157543549496.5882_C-terminusofdelta-9fattyaciddesaturase
195105___________ +1.09 +1.110.2630.3480.2041847620199204186.6345_transcriptionactivator
196696___________ -1.39 -1.290.0310.0460.0632287016455177676.6805_mitochondrialinnermembranetranslocase
194436___________ +1.02 +1.060.2420.3080.2001486415227156846.7248_glutathioneperoxidase
195246___________ +1.03 +1.030.4450.3290.4701334613684137246.7696_hypotheticalprotein
197243___________ +1.18 +1.240.0060.0270.0101587718768196616.8143_deoxycytidylatedeaminase
197414___________ -1.17 -1.160.0350.0450.0761885016076162776.8575_
197675___________ -1.11 -1.090.0180.0310.0401272111432117066.9023_mitochondrialribosomalproteinMRPL25
*193873___________ +1.18 +1.300.0070.0270.0113832545226498476.32___
195124___________ +1.25 +1.240.0010.0040.0041863623333231906.524__
19194____________ +1.19 +1.200.0050.0100.0181326315738158966.1143_
1969_____________ +1.06 +1.000.2050.0950.7441383514731138566.1692_hypotheticalprotein
*193600___________ +1.36 +1.420.0010.0030.0062067628202292856.2227_hypotheticalprotein
193633___________ +1.58 +1.380.0020.0040.0131357821416186716.2748_transthyretinprecursor(Prealbumin)
*194332___________ +1.52 +1.350.0020.0040.0101545423429208166.3254_
19848____________ +1.20 +1.080.0220.0150.1611318515762142446.3746_hypotheticalprotein
*194412___________ -1.36 -1.280.0030.0060.0132974321818231956.4227_
194657___________ +1.26 +1.240.0060.0150.0151325816739163906.4708_NuclearEnvelopeMorphology
*192404___________ +1.20 +1.280.0110.0490.0144031848442515386.5188_
193984___________ +1.26 +1.160.0070.0120.0251312516558152686.5660_
*192903___________ +2.21 +2.340.0000.0000.0003779783496883686.6119_conservedhypotheticalprotein
*192761___________ -1.13 -1.130.0300.0540.0522877425353255606.6591_
*191885___________ +1.32 +1.460.0010.0070.0023363244257491306.7036_
192066___________ -1.01 -1.040.4860.4800.3761743617342167796.7489_conservedhypotheticalmembraneprotein
197010___________ +1.46 +1.500.0010.0030.0051473521484220696.7936_conservedmembraneproteinwithBTB/POZdomain
*197300___________ +1.34 +1.550.0010.0040.0021902225484294106.8381_hypotheticalprotein
*196814___________ -1.85 -1.830.0020.0040.0066739403643003677446.8816_
Cafen1___________ +1.00 -1.050.3530.9610.181118311187311289Cafen1_
*194145___________ +1.36 +1.220.0060.0080.0321332818129163266.236__
*191208___________ +3.66 +3.320.0000.0010.0011826266794606846.841__

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*194780___________ -1.58 -1.330.0000.0010.004155623986031174166.1422_multidrugtransporter
*191914___________ +1.31 +1.240.0010.0030.0081966325663243566.1965_hypotheticalprotein
194065___________ +1.21 +1.070.0210.0170.1171273015404135976.2483_hypotheticalprotein
191247___________ +1.10 +1.070.1030.0650.3111288214118138266.3012_
194265___________ +1.16 +1.150.0080.0210.0181990823159228026.3492_UDP-n-acetylglucosaminepyrophosphorylase
194348___________ +1.27 +1.250.0090.0120.0341395817710174166.3992_transcriptionalregulation
*195518___________ +2.33 +2.000.0000.0010.0011682439197337006.4460_hypotheticalprotein
195853___________ +1.03 +1.080.1080.2570.0832070121356223286.4955_
*196205___________ +1.16 +1.140.0070.0130.0222800532391320556.5419_conservedhypotheticalprotein
*192249___________ -1.54 -1.540.0020.0050.0053023719662196556.5897_neutralzincmetallopeptidase
192001___________ -1.00 +1.030.8830.8660.6832624626141269066.6359_conservedhypotheticalprotein
*194117___________ +1.23 +1.300.0020.0080.0032996836817388616.6819_hypotheticalprotein
194448___________ -1.14 -1.160.3180.2580.3555717050301492906.7261_leucine-richrepeatprotein
*195232___________ +1.67 +1.590.0000.0020.0012373139564378296.7710_conservedhypotheticalprotein
197257___________ +1.14 +1.080.0410.0290.1831275414557137196.8156_
*197433___________ +2.13 +2.180.0010.0040.0031781437883388216.8589_
196001___________ +1.06 +1.010.2540.1170.8511251213219126056.9036_secretedaspartylproteinase
194080___________ +1.19 +1.220.0110.0370.0171384416477169416.49___
195182___________ +1.21 +1.220.0040.0120.0091229714868149546.546__DNA-directedDNApolymerasedelta,catalytic125KDsubunit
191804___________ +1.05 +1.030.2520.2060.3131294613579133936.1161_putativemitochondrialtransporter
194697___________ +1.01 -1.010.5090.2730.9281325213368130906.1710_
191391___________ +1.10 +1.010.1380.0620.6961294814235130796.2243_dynactinsubunitP25
194219___________ -1.01 -1.010.9470.7980.8841169411562115686.2763_
192859___________ +1.02 +1.010.6140.4010.6971252712839126346.3270_
193458___________ +1.03 +1.020.5870.4200.5901244212802127116.3761_
*191283___________ +1.26 +1.250.0110.0330.0191879823640234086.4241_
*19575____________ +1.23 +1.320.0090.0510.0111906023504252086.4724_
194284___________ -1.01 -1.010.6730.4050.9291195011884118846.5202_pombecyclinChomologue
196139___________ -1.01 -1.020.7560.9030.5061230612182120256.5675_ferricreductase
192890___________ -1.05 -1.050.1490.0950.3461336712780127346.6132_conservedhypotheticalprotein,putativeUDP-galactosetransporter
194241___________ -1.03 -1.050.1840.1950.2051274412376121736.6604_hypotheticalprotein
191871___________ +1.22 +1.230.0100.0400.0151347016378165166.7050_
193809___________ -1.01 -1.040.6600.9580.4081208111908115926.7503_
197023___________ +1.06 +1.000.4180.2160.8291622417124162996.7949_PWWPdomainprotein
197313___________ -1.04 -1.040.4520.3760.4201225211827118186.8394_sulfitesensitivityprotein
196802___________ -1.06 -1.050.1710.2050.1781175611064111456.8829_conservedhypotheticalprotein
Casfl1___________ -1.05 -1.040.1460.3580.098117941126911320Casfl1_
*192467___________ +1.51 +1.410.0010.0030.0021470622191207126.251__
*191190___________ -1.73 -1.680.0030.0050.0138506249157507136.860__
19120____________ +1.15 +1.170.0050.0140.0121324615237154566.1441_
191954___________ +1.25 +1.210.0130.0450.0181767822021213316.1980_
*193681___________ +1.48 +1.400.0030.0110.0081571023303219616.2498_karyopherin-betainvolvedinnuclearimport
193229___________ +1.07 +1.190.0130.0310.0261378714756163556.3028_hypotheticalprotein
193965___________ +1.21 +1.170.0060.0170.0131255215175147386.3506_hypotheticalprotein
192941___________ +1.20 +1.090.0870.0570.2691282315328139406.4005_cellwallglucanase
193177___________ -1.04 +1.040.4940.3630.5064603944070478636.4474_DRAPdeaminase|riboflavinbiosynthesis
192465___________ +1.13 +1.090.0360.0490.0731261414244137806.4969_
196282___________ +1.03 +1.040.3620.3900.2901261813018131756.5432_
194930___________ +1.13 +1.050.4170.4480.3182308426063242866.5910_signalpeptidasesubunit
191411___________ +1.22 +1.170.0080.0230.0161502618260176126.6380_CytochromeP450
194101___________ -1.06 -1.100.0360.1070.0391201111337109266.6835_hypotheticalprotein
*19903____________ -1.35 -1.480.0140.0320.0275371433966283624876.7274_phosphoglyceratemutase
*196977___________ +1.64 +1.780.0000.0030.0011909331322339956.7723_glycosylphosphatidylinositolsynthesis|participatesinsynthesisofN-acetylglucoaminylphosphatidylinositol,thefirstintermediateinsynthesisofglycosylphosphatidylinositol(GPI)anchors
197272___________ -1.04 -1.050.3370.5630.2051154611053110106.8172_hypotheticalprotein
197443___________ +1.03 -1.010.5770.7190.3712341024118230656.8603_hypotheticalprotein
195986___________ -1.04 -1.030.1380.0700.5131604615450156106.9051_involvedinthiaminebiosynthesispathwayandDNArepair
1959_____________ +1.14 +1.210.0580.0900.0821781320379215406.73___
19867____________ +1.28 +1.210.0030.0040.0171268716303153156.567__
19147____________ +1.29 +1.220.0020.0040.0091334017154162726.1179_serine-threonineproteinkinase,PKAsuppressor
19706____________ +1.23 +1.310.0060.0190.0101796222037235196.1726_
191488___________ +1.34 +1.230.0040.0060.0291391418681170486.2260_hypotheticalprotein
195742___________ +1.18 +1.080.0260.0220.1211302615320140676.2783_
*193616___________ +1.46 +1.310.0020.0040.0091651424138216696.3286_farnesyl-diphosphatefarnesyltransferase|squalenesynthetase
*194362___________ -1.21 -1.160.0210.0280.0553108025704268846.3776_40kDaputativemembrane-spanningATPase
*191832___________ +1.96 +1.850.0000.0010.0011635631990303396.4254_putativepyridoxinetransporter
192120___________ +1.21 +1.140.0090.0130.0311231014899140426.4741_hypotheticalprotein
194811___________ -1.02 -1.030.4690.9120.2571491214652144316.5216_
19592____________ +1.18 +1.080.0270.0220.1301275415106137906.5689_
195833___________ -1.03 -1.080.2790.7010.1482244621843207486.6145_ubiquitinfusiondegradationprotein
*194225___________ +1.25 +1.410.0050.0170.0093083238433434066.6619_
*19504____________ +1.20 +1.240.0300.1080.0316609779198816756.7067_vacuolartargeting,actin-relatedprotein
193823___________ +1.24 +1.210.0110.0180.0301374216980166476.7519_
*197036___________ +1.18 +1.080.0060.0100.0222424828568262246.7962_involvedingrowthregulation
*197325___________ -2.33 -2.190.0020.0050.0074128817708188856.8406_innermitochondrialmembraneprotein
196789___________ -1.05 -1.020.5830.5930.4232002719149195436.8842_spindlepolebodyprotein
41875____________ +1.01 -1.060.2870.8100.1461179811938110864.1875_
19720____________ +1.17 +1.200.0030.0060.0111525817886183436.271__
196349___________ +1.48 +1.310.0010.0020.0081380020446180286.877__
*192636___________ +1.33 +1.540.0000.0020.0003904851973601546.1457_conservedhypotheticalprotein
19248____________ +1.50 +1.280.0030.0050.0151427221350182976.1993_
*194125___________ +1.38 +1.160.0030.0040.0271693423329197036.2514_transcriptioninitiationfactorTFIIIA
194526___________ -1.11 -1.110.0930.0730.2142073818654187316.3045_plasmamembraneheatshockprotein
19635____________ +1.19 +1.060.0870.0360.9351371416301145376.3522_hypotheticalprotein
194748___________ +1.27 +1.170.0070.0080.0461253515859146866.4018_U2snRNA-associatedprotein
192829___________ -1.02 -1.040.3490.8380.1831889018453181286.4490_conservedhypotheticalprotein
193477___________ +1.27 +1.260.0270.0540.0441467218668184496.4982_tRNApseudouridinesynthase
196298___________ +1.23 +1.210.0080.0190.0191552819143188466.5448_ATPdependentRNAhelicaseinvolvedinthematurationof25SribosomalRNA
1931_____________ +1.33 +1.160.0020.0030.0201507320105175196.5925_potentialcellwallprotein|memberofagroupofC.albicansorfsthatareweaklysimilartoScCIS3/PIR3/PIR1�orf6.5925
191424___________ +1.18 +1.200.1580.2280.1453497141227419046.6393_conervedhypotheticalprotein
*194088___________ -1.18 -1.150.0170.0340.0346381054280553106.6848_hydroxyacylglutathionehydrolase
*19886____________ +1.91 +1.520.0000.0010.0032270643413345386.7289_
196989___________ +1.23 +1.080.0140.0090.2641276715714138356.7735_putativesplicingfactor|RNA-bindingdomain
19937____________ +1.09 +1.030.1320.0650.5291262513767130306.8186_hypotheticalprotein
197455___________ +1.28 +1.110.0050.0060.0441473618916163136.8615_hypotheticalprotein
195973___________ +1.02 +1.030.5650.3620.6691207812284124516.9064_mitochondrialprohibitin
194548___________ +1.22 +1.090.0230.0290.0651599419440173706.96___necessaryforstructuralstabilityofL-AdsRNA-containingparticles
194398___________ +1.09 +1.080.0270.0630.0391203413118130226.587__conservedhypotheticalprotein
1911242__________ +1.21 +1.160.0380.0630.0621929623397223846.1200_NA
193152___________ +1.14 +1.040.0750.0340.6041261514369131466.1742_copper-containingamineoxidase
193952___________ +1.08 +1.030.1910.1140.4221437815499148456.2276_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194342___________ +1.05 +1.040.2570.2370.2771216612808126416.2799_conservedhypotheticalprotein
194919___________ +1.02 +1.030.8120.7510.6281272612950130626.3299_
195723___________ +1.03 -1.000.6270.5740.4861309813474130906.3796_acyl-coenzymeAoxidase
192616___________ +1.04 +1.040.2900.2050.3971289913446134206.4269_
192104___________ +1.00 -1.030.9970.9640.9601196512004116286.4757_molecularchaperone|maybeinvolvedinassembly/maturationofmitochondrialiron-sulfurproteins
194146___________ +1.04 +1.010.4920.3130.6091203812463121216.5233_
192984___________ -1.06 -1.070.0670.1250.0761277212064119896.5705_mitochondrialthreonyltRNAsynthetase
195820___________ -1.00 -1.010.8520.8960.6261207012056119436.6158_
*195801___________ +1.36 +1.240.0080.0200.0171543420951191006.6635_smallsubunitofribonucleotidereductase
*19489____________ -1.63 -1.740.0010.0030.0013137519274180306.7082_putativesterol-bindingprotein
193839___________ +1.01 +1.070.2080.4700.1271324013341141936.7534_secretoryaspartylproteinase
195033___________ -1.07 -1.080.0750.1490.0771190211080110376.7976_proteininvolvedinprotein-vacuolartargeting
197339___________ -1.02 -1.040.3050.6450.1701227812044117736.8420_beta-glucosidase2precursor
196777___________ -1.05 -1.090.0640.2260.0491211511509111466.8854_hypotheticalprotein
42400____________ -1.05 -1.090.0650.3580.0401174611137107934.2400_
1935_____________ +1.56 +1.400.0010.0030.0041354021181189816.286__
*193192___________ +1.49 +1.610.0050.0110.0151698925323273726.905__
*1967_____________ +1.67 +1.660.0010.0060.0021965932742326416.1472_hypotheticalprotein
*191051___________ +3.50 +3.380.0000.0010.0012067272309699716.2007_histone2A
*192751___________ +1.64 +1.610.0010.0030.0021462323982235636.2533_
194798___________ +1.05 +1.080.7980.9110.5532238423431241206.3057_membraneproteinwithweaksimilaritytomyosins
191502___________ +1.19 +1.180.0060.0140.0141255614919148796.3540_
195100___________ +1.16 +1.090.7980.6590.6752731331765296896.4035_ATP-dependenttransporter
*195635___________ -5.19 -5.880.0000.0000.00020291339082344886.4504_glycosyl-phosphatidylinositolprotein|similartoRBT5
194515___________ +1.28 +1.280.0040.0120.0091496419210191806.4996_poptentialcellwallproteinofthePIRfamily
194675___________ +1.26 +1.210.1800.1010.4581286816216155726.5461_conservedhypotheticalprotein
19207____________ +1.03 +1.040.3570.4560.2521251012941130246.5941_
191548___________ -1.02 -1.080.1770.4820.1042018319693186546.6406_U4/U6.U5snRNPassociatedprotein|RNAbindingzincfingerprotein(putative)
196712___________ +1.27 +1.270.0840.2040.0713144239822399276.6860_
19874____________ -1.00 -1.000.7730.5070.9321939219296193416.7303_conservedhypotheticalprotein
*197002___________ +6.68 +11.780.0000.0010.00013519903731593176.7748_hypotheticalprotein
19949____________ +1.04 +1.070.2030.2360.1981263413196134746.8199_
*195392___________ +4.30 +5.340.0000.0000.0001504964663803806.8628_conservedhypotheticalprotein
195961___________ -1.00 -1.320.1370.5250.0753762537599285446.9076_ankyrinrepeatproteinthatinteractswiththe19Sregulatoryparticleofthe26Sproteasome
192115___________ -1.08 -1.070.1440.2640.1163528632566328536.117__
1936_____________ +1.29 +1.160.0030.0040.0191235515883143756.608__putativeConservedOligomericGolgicomplex8
*191656___________ +1.71 +1.690.0000.0020.0012064835348349606.1219_conservedhypotheticalprotein
*193221___________ +1.53 +1.480.0000.0010.0013088047120457616.1765_carbamoylphosphatesynthetaselargesubunit,argininebiosynthesis
193775___________ +1.41 +1.200.0020.0050.0111450020436173856.2292_
*194406___________ -1.30 -1.280.0050.0100.0154143131969324036.2822_Ngg1p-interactionfactor
*195037___________ +1.73 +1.580.0010.0020.0041735530049274166.3314_conservedhypotheticalprotein
192560___________ -1.03 -1.040.3710.8090.1982722726421261676.3809_
*193537___________ +1.86 +1.790.0010.0030.0021328024669237726.4283_conservedhypotheticalprotein
*195615___________ +1.45 +1.300.0020.0040.0061666824109216766.4774_
193862___________ +1.01 +1.060.5510.7910.3333562835828378396.5252_requiredforaminoacidpermeasetransport
192970___________ +1.01 -1.040.3470.7650.1862005420203192606.5719_
192492___________ +1.09 +1.080.0630.0640.1321253813611135206.6172_
192965___________ -1.08 -1.050.2640.1540.4984691643589445646.6651_pump-drivingATPase
*191476___________ -1.40 -1.600.0030.0090.0104084229102255336.7097_activatorofIME1|meiosis|methyltransferase(putative)
196563___________ +1.21 +1.170.0080.0140.0241392416870162406.7551_conservedhypotheticalprotein
*195020___________ +1.72 +2.070.0000.0030.0011905032717394886.7989_conservedhypotheticalprotein
197121___________ +1.04 +1.020.2220.1580.3511628716934166346.8431_
*196763___________ +1.21 +1.510.0140.0600.0171647311985792489396.8870_
42612____________ +1.04 +1.010.3800.1930.8121199812479120974.2612_
*196260___________ +1.99 +1.580.0010.0020.0062080941342329456.302__
191759___________ +1.34 +1.190.0040.0050.0201307917542155816.926__
*194643___________ +1.76 +1.380.0020.0030.0141327023341182996.1491_
194463___________ +1.34 +1.240.0040.0070.0181282617181159016.2029_
*19802____________ +3.05 +2.520.0000.0000.0012735083457689376.2548_
*196965___________ -1.48 -1.430.0010.0040.0044129627819289016.3071_
192457___________ +1.18 +1.090.0100.0100.0691489917652162436.3558_hypotheticalprotein
193926___________ +1.27 +1.170.3190.1530.8441338316939156156.4050_ribonucleasefromtheT2family
195648___________ -1.12 +1.010.2710.1260.8583715433306373646.4517_putativenuclearexportfactor
194210___________ +1.02 +1.020.4550.2360.9001970720134200136.5011_epoxidehydrolase
*193746___________ +5.57 +5.920.0000.0000.000329581835241952496.5476_oligopeptidetransporterprotein
195141___________ +1.21 +1.060.0190.0110.3041210814689128856.5957_hypotheticalprotein
*191563___________ +1.69 +1.770.0000.0010.0002545242923449576.6420_membraneproteininvolvedincellwallbiogenesisandarchitecture|calcofluorsensitivity
196726___________ +1.01 +1.010.9430.7560.9983957639940401006.6875_weaksimtoSPT2transcriptionalsilencer
*196930___________ +1.80 +1.800.0000.0010.0012276441002409466.7316_hypotheticalprotein
193023___________ +1.15 +1.080.0270.0210.1451392815955150056.7762_
*19964____________ +1.39 +1.300.0120.0160.0401337218530173696.8214_
*195408___________ +2.36 +2.570.0000.0000.0002171051318558006.8644_proteinkinase
195947___________ +1.09 +1.040.1130.0700.3281199613041124546.9092_
19206____________ +1.10 +1.110.0710.1250.0821239213671137276.130__
192740___________ +1.24 +1.200.0060.0130.0171225215182147626.635__
*193171___________ -4.66 -5.460.0010.0030.0029558020529174906.1238_
193288___________ +1.21 +1.140.0180.0530.0261564118899178936.1778_conservedhypotheticalprotein
193851___________ +1.13 +1.130.0240.0300.0671314814811148276.2312_hypotheticalprotein
194966___________ +1.02 +1.040.3330.4560.2291176212004122736.2839_probablemitochondrialcarrierprotein
19703____________ +1.01 -1.020.9840.9840.8781586416046155596.3327_2',3'-cyclicnucleotide3'-phosphodiesterase
192639___________ -1.03 +1.020.4470.8560.2451381713407140856.3824_mitochondrialribosomallargesubunitproteinYmL20
19298____________ -1.16 -1.240.0040.0220.0072425020938196086.4295_hypotheticalprotein
195630___________ +1.09 +1.040.1700.1390.2611370814977143176.4789_ATPadenylyltransferaseII
196550___________ +1.01 -1.010.9210.7330.8891223612302121556.5265_
191265___________ -1.00 -1.020.8300.8440.6101211512055118716.5732_targetingcomplex(TRAPP)componentinvolvedinERtoGolgimembranetraffic
195768___________ -1.01 -1.000.9130.7390.8441290612779128466.6190_nuclearprotein
192953___________ -1.10 -1.090.0540.0740.0881432413034131696.6663_mitochondrialoutermembraneimportreceptorsubunit
*191461___________ +5.87 +6.770.0000.0000.0001381981140935296.7112_conservedhypotheticalprotein
196579___________ -1.04 -1.010.7110.4420.9191198811518118996.7567_hypotheticalprotein
*195006___________ -1.09 -1.590.0370.1280.0363931036036246906.8003_H-proteinsubunitofglycinecleavagesystem
197107___________ +1.27 +1.160.1040.1880.0983784248118440496.8446_conservedhypotheticalprotein
*196749___________ +1.36 +1.450.0020.0120.0031896725793274286.8881_
42795f++1________ -1.04 -1.070.2240.8860.1101278612312119754.2795f
*193599___________ +1.37 +1.240.0010.0020.0031870425552231466.318__
192309___________ +1.30 +1.320.0020.0070.0041326017295175696.943__
61508____________ +1.11 +1.140.0140.0300.0281255113882143616.1508_
*193586___________ +1.35 +1.320.0090.0580.0112088928268276086.2044_
19113____________ +1.17 +1.090.5090.3810.5061210414205132516.2562_
63086____________ +1.06 +1.040.1690.1970.1801225912954127586.3086_
*192268___________ -2.35 -2.310.0000.0010.00210384844140449046.3573_Ca2+/calmodulin-dependentserine/threonineproteinkinase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194673___________ +1.18 +1.190.0180.0410.0301293215261153526.4063_hypotheticalprotein
*194371___________ -1.83 -2.190.0020.0040.0063499101912301600856.4536_transaldolase
193330___________ +1.15 +1.140.0210.0450.0361418516313162356.5024_GTP-bindingprotein
192703___________ +1.18 +1.160.5050.2730.8671447817148168616.5490_
*192032___________ +1.82 +1.800.0010.0030.0032997654558540146.5971_hypotheticalprotein
*191638___________ +2.63 +2.890.0000.0010.0002160056902624816.6434_componentofCOPIIcoatofER-golgivesicles,GTPaseactivatingprotein
*195649___________ -2.82 -3.200.0000.0000.0008144028830254836.6889_
*196944___________ -1.31 -1.380.0180.0240.0534801436774348976.7331_
*193040___________ +1.92 +2.090.0000.0050.0014396884432918066.7777_alcoholacyltransferase
*19979____________ +1.44 +1.680.0020.0170.0021593422953268296.8228_fatty-acyl-CoAsynthase,betachain
195422___________ +1.16 +1.140.0540.2270.0401797020896204886.8658_hypotheticalprotein
195931___________ +1.15 +1.160.0080.0230.0151422316297165266.9106_involvedinsteroluptakeanddistributionintotheplasmamembrane
19160____________ +1.27 +1.260.0020.0030.0101251815877157566.146__
196259___________ +1.37 +1.190.0020.0030.0131270417459150676.654__
191859___________ +1.43 +1.200.0030.0040.0231287418381154526.1254_
193387___________ +1.02 +1.030.5440.6490.3613735337944385976.1800_reversetranscriptase
*192506___________ +1.52 +1.370.0020.0040.0081398521319191086.2329_
19459____________ +1.07 +1.080.5760.3610.7032614628085281736.2855_ATP-dependentpermease|membranetransporterABCsuperfamily
*193335___________ -3.07 -2.750.0000.0000.00023262775817846776.3342_hypotheticalprotein
194881___________ -1.06 +1.030.2940.1820.4802467723354255206.3840_hypotheticalprotein
*194476___________ +1.27 +1.300.0000.0020.0011959424819254176.4311_aryl-alcoholdehydrogenase
19279____________ +1.11 +1.060.0990.0600.3251438015956151976.4808_d-tyr-tRNA(tyr)deacylase
1930101__________ +1.09 +1.000.9110.9300.7092842630947285016.5278_NA
191669___________ -1.14 -1.070.0980.0540.3844032935496377896.5744_ATPdependentmetalloprotease
196595___________ +1.05 +1.050.6370.6240.4681241212984130016.6207_putativetransporterorflippasethattranslocatesLCBsfromthecytoplasmicsidetowardtheextracytoplasmicsideofthemembrane
194529___________ +1.01 -1.000.8900.6570.9701849018747184226.6676_
191447___________ +1.32 +1.400.0010.0050.0041652221864231416.7126_
196035___________ +1.04 +1.000.3680.1900.7581359514115136526.7579_ubiquinoneoxidoreductase
*194991___________ +1.13 +1.170.0110.0240.0232083623628244396.8017_
197094___________ +1.12 +1.080.0170.0100.2641269014179136796.8459_glucosesensorortransporterprotein
*197547___________ +1.41 +1.400.0020.0050.0102023928616283256.8895_phosphatidylinositol(3)-phosphatebindingprotein
42858f___________ -1.02 +1.020.7270.4930.7781257012287128034.2858f
194470___________ +1.17 +1.130.0050.0090.0211222414247138696.335__
191330___________ +1.48 +1.270.0020.0030.0091493222057190106.959__hypotheticalprotein
195065___________ +1.37 +1.260.0040.0060.0221346218503169366.1522_requiredforretentionofluminalERproteins
*19367____________ +1.43 +1.280.0160.0190.0563810954496488876.2061_
*193370___________ +1.83 +1.720.0000.0010.0002393543765411396.2580_
*191313___________ +1.93 +1.760.0020.0040.0081497428864263166.3101_opaque-specificmultidrugresistancetransporter
192756___________ +1.22 +1.140.0060.0070.0411333216284151386.3588_HDELreceptorforERproteinretention
*192362___________ +1.53 +1.580.0010.0040.0031576324093248906.4078_involvedinrRNAprocessing
*1955_____________ +1.36 +1.710.0000.0030.0002701836670460806.4551_conservedhypotheticalintegralmembraneprotein
*191967___________ -2.01 -1.890.0010.0020.0025637028053298436.5037_mitochondrialribosomalprotein
*196315___________ +2.06 +1.800.0010.0020.0031523631344274346.5508_hypotheticalprotein
192044___________ +1.07 +1.020.1400.0660.6091408615098144316.5983_hypotheticalprotein
*191623___________ +1.75 +1.610.0000.0010.0005196391133837736.6449_transcriptionalactivatorinvolvedinoxidativestressresponse
*195663___________ -1.46 -1.360.0010.0030.0072988520429219806.6903_conservedhypotheticalprotein
194861___________ +1.06 +1.040.0610.0360.2911305513830135936.7351_
*193052___________ +2.09 +2.230.0000.0000.000708031477031577046.7789_GTP-bindingproteinoftherabfamily
193241___________ +1.17 +1.120.0070.0090.0311951022799218896.8241_hypothticalprotein
*195436___________ +1.42 +1.690.0010.0080.0022128630186360416.8670_
*195917___________ +11.76 +8.480.0000.0000.000214502523461818936.9120_zincfingerproteininvolvedinpre-tRNAsplicing
1942_____________ -1.07 -1.060.0940.1930.0841179010970110896.7____transportprotein
*196242___________ +1.47 +1.310.0080.0160.0221304819193171326.674__hypotheticalprotein
*19246____________ +1.30 +1.250.0010.0030.0071824823748227316.1273_
*192887___________ +2.48 +2.360.0000.0000.000565501403321332296.1818_
193894___________ -1.09 -1.110.0280.2260.0201188410868106946.2345_Myo-inositoloxygenase
191766___________ +1.29 +1.260.0200.0240.0661242316022156836.2871_similartoputativehydrolase
196494___________ -1.06 -1.090.0450.1910.0351177711123108236.3360_
192394___________ +1.20 +1.140.0110.0120.0581222614705139346.3854_
*193405___________ +1.68 +1.610.0000.0000.0002776146618445896.4326_hypotheticalprotein
*19607____________ +2.35 +2.300.0000.0010.0013400279876783236.4823_
*191359___________ +1.30 +1.240.0160.0190.0612388131077296896.5291_hypotheticalprotein
193571___________ +1.13 +1.120.0430.0380.1371293514631144326.5758_hypotheticalprotein
*196608___________ +1.72 +1.650.0010.0030.0023028652065498726.6221_
*194542___________ +1.22 +1.130.0300.0280.1073223039425364116.6688_cyclin|TFIIKsubunit,asubcomplexoftranscriptionfactorTFIIH
*196875___________ +1.17 -1.010.0230.0100.7414805056297475926.7139_retrievalofvacuolarsortingreceptor
196048___________ +1.12 -1.050.0820.0510.2943231836343306536.7592_mannosyltransferase
*197136___________ +1.96 +1.740.0010.0030.0041926937854336126.8033_
*197080___________ -1.67 -2.170.0010.0050.00110128460595465966.8473_isopropylmalatedehydrogenase
197558___________ -1.01 -1.040.3120.7470.1661486014652142336.8908_
43104____________ +1.01 -1.020.6440.7930.4151432314512141054.3104_
*191555___________ +1.71 +1.480.0010.0020.0062572644065379696.355__involvedinprocessesaffectingtheactincytoskeletonandmitosis|leucinepermeasetranscriptionalregulator
191348___________ +1.27 +1.200.0020.0040.0101319816767158236.981__hypotheticalprotein
192869___________ +1.14 +1.060.0240.0160.1821252114260132236.1537_hypotheticalprotein
*191382___________ +1.33 +1.270.0010.0020.0031747323245221916.2082_
193769___________ +1.27 +1.220.0010.0020.0031654121036201356.2598_
*191709___________ -1.60 -1.740.0010.0070.0028735654494501006.3118_sterolcarrierprotein
*192786___________ +1.91 +1.740.0000.0010.0011870535662324936.3603_clathrinassociatedproteincomplexlargesubunit
*191757___________ +1.69 +1.710.0220.0200.0961854231377317526.4092_transcriptionalregulatorcontainingaC2H2zincfinger
195685___________ -1.06 -1.060.2200.1400.4071237801165121166886.4563_threonyl-tRNAsynthetase
195859___________ +1.18 +1.180.0150.0420.0231378016263162766.5051_allantoatepermease
*196329___________ +1.36 +1.340.0000.0010.0012181729729292766.5523_
*196460___________ +1.43 +1.370.0050.0090.0161843126278251756.5999_AAAATPase,peroxisomalbiogenesis
193442___________ +1.08 +1.100.0860.1020.1284343847008477176.6463_NADPHdehydrogenase
*195677___________ +1.72 +1.810.0020.0080.0051536426425278486.6917_ureapermease
*194845___________ +1.84 +2.010.0000.0020.00149740913801000926.7366_conservedhypotheticalprotein
*193064___________ -2.83 -2.890.0000.0000.00012532344323434216.7801_mitochondrialribosomeproteinL27
193254___________ +1.03 +1.020.2630.1280.7191361014058138226.8253_
*195447___________ -15.14 -12.960.0000.0000.00059384239218458066.8683_sugartransporter
*195904___________ +1.23 +1.280.0090.0170.025943051161771211486.9133_ribosomalproteinL19A(L23A)(rpl5L)(YL14)
*192003___________ +2.03 +1.800.0000.0000.0012021140993363476.42___
194863___________ +1.10 +1.080.1180.0540.6172460027009265356.690__
*196225___________ +1.98 +1.910.0000.0000.0003125461896597026.1290_
*193724___________ +1.51 +1.840.0000.0020.0002835742903520546.1835_processingof20Spre-rRNA
*19262____________ +1.39 +1.280.0040.0050.0261379619244177086.2358_
193368___________ +1.19 +1.060.0300.0160.3731242814749132356.2892_hypotheticalprotein
192521___________ +1.51 +1.370.0010.0030.0051488222407203756.3374_
192378___________ -1.04 -1.080.2470.4170.1672944528390271906.3870_
*192201___________ -1.54 -1.400.0020.0050.0053588223367256226.4340_pre-mRNAprocessingprotein|translationalactivator
*191722___________ -1.37 -1.240.0020.0030.0253052422328246196.4838_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*193707___________ -2.93 -2.560.0000.0000.0003048001041521192066.5305_
*196343___________ +1.46 +1.390.0000.0010.0012471536058342386.5772_involvedinsynthesisof1,3-beta-glucan,acomponentofthecellwall,andelongationoffattyacidsupto24carbons|1,3-beta-glucansynthasesubunit|fattyacidelongaserequiredforsphingolipidformation
*196105___________ -1.37 -1.150.0110.0130.0549579070032835236.6236_mevalonatepyrophosphatedecarboxylase
19812____________ +1.13 +1.060.0740.0420.3481247214155131756.6703_hypotheticalprotein
*196891___________ +1.96 +1.700.0010.0030.0061735434043295756.7154_
*196061___________ +1.38 +1.330.0020.0050.0051820825152241336.7605_conservedhypotheticalprotein
*197150___________ +2.12 +3.150.0000.0000.0001137732409243585746.8050_transcriptionalrepressor
197067___________ -1.01 +1.050.9230.8420.7699029289578950146.8487_
*197574___________ +2.42 +2.810.0000.0010.0012101250927589486.8923_
K_actin__________ +1.09 +1.060.1700.1120.351127011381213459Kactin_
19568____________ +1.12 +1.140.1920.2910.1551677018861190396.371__
*192549___________ +1.58 +1.570.0010.0040.0031511623829238026.1004_
193960___________ +1.00 +1.070.5100.6950.3171991819956212526.1553_DNA-directedDNApolymerasedelta
193409___________ +1.31 +1.230.0170.0250.0451229916146150796.2097_
194155___________ +1.03 -1.000.2480.1140.8261200412389119646.2619_hypotheticalprotein
191159___________ +1.25 +1.180.0120.0210.0301472318381173666.3134_homoserineO-acetyltransferase
*192439___________ -1.51 -1.350.0040.0050.0343320022026245266.3617_mitochondrialacylcarrierprotein
*192590___________ +1.92 +1.620.0010.0020.0101302224973211536.4109_
*192814___________ +1.57 +1.840.0000.0010.0001939530545355966.4579_hypotheticalprotein
195608___________ +1.18 +1.210.0030.0100.0081542418217186496.5064_DNA-directedRNApolymeraseIII
192310___________ +1.03 +1.020.3930.2390.5751221012607125016.5540_conservedhypotheticalprotein
19732____________ +1.00 -1.020.7580.6190.6431337513423131266.6011_carbonylreductasesimilartoSOU1andSOU2
*193665___________ +1.11 +1.190.0050.0810.0043126334648371906.6476_putativeHLHtranscriptionfactor
193116___________ +1.19 +1.200.0030.0120.0051741720710209126.6929_yeastU1snRNPproteinwitharolein5'splicesiterecognition
*194830___________ +1.29 +1.310.0000.0010.0012301529754302516.7381_hypotheticalprotein
*196440___________ +1.22 +1.340.0040.0130.0092215426966297816.7815_
193267___________ -1.02 -1.030.6980.8220.4601219111981118326.8267_DHHCzincfingerprotein
*195462___________ -1.60 -1.260.0090.0090.0728443052832672346.8698_hypotheticalprotein
195892___________ +1.05 +1.020.6460.4470.6701228212928125416.9148_
191745___________ +1.07 +1.020.1540.0780.5321327314241135136.70___
194866___________ +1.24 +1.170.0070.0090.0351264915625147636.707__probableprotein-tyrosinephosphatase
*195758___________ +3.39 +3.220.0010.0030.0041847462717594726.1305_
*193143___________ +1.45 +1.350.0020.0030.0122536436769341166.1854_transposase
192024___________ +1.20 +1.110.0100.0090.0891290915521143186.2375_hypotheticalprotein
19169____________ +1.09 +1.090.2080.1110.5371481716086161896.2905_phosphatidyl-ethanolamineN-methyltransferase
195049___________ +1.20 +1.150.0050.0060.0441277815310147116.3388_
*191332___________ +1.58 +1.400.0000.0010.0042586040763361356.3885_drugtransporter
*195505___________ +1.33 +1.170.0010.0030.0072696635764314986.4353_imidazoleglycerolphosphatesynthase|histidinebiosynthesis
195779___________ -1.12 -1.140.0100.0320.0161167410420102736.4850_
196156___________ -1.14 -1.140.0100.0330.0151172510327102686.5317_conservedhypotheticalprotein
196358___________ -1.28 -1.170.0050.0110.01311628908899446.5787_ubiquitinconjugatingenzyme
196090___________ -1.14 -1.160.0260.0510.0431228410791106226.6253_
19828____________ -1.16 -1.140.0070.0170.016115469961101236.6719_mitochondrialribosomalprotein
196904___________ -1.16 -1.110.0070.0160.0181167410059105206.7168_translationinitiationfactoreIF2Bsubunit
196074___________ -1.13 -1.140.0130.0510.0171176410394103116.7618_nuclearproteininvolvedinoxidativestressresponse
197163___________ -1.11 -1.150.0070.0480.0091169410498101686.8063_hypotheticalprotein
197054___________ -1.19 -1.130.0070.0150.017116969806103736.8499_hypotheticalprotein
197590___________ -1.22 -1.170.0020.0060.00711674958099956.8938_
19620____________ +1.26 +1.170.0080.0090.0451303716382152566.387__hypotheticalprotein
195177___________ +1.20 +1.140.0150.0190.0511251214968143266.1026_
*196252___________ +1.23 +1.090.0300.0200.2052467430328269406.1568_conservedhypotheticalprotein
*195741___________ +2.42 +2.010.0000.0010.0011560137771313956.2112_agglutininlikeprotein1
19712____________ +1.29 +1.190.0040.0070.0171242815997147896.2633_kinesin-relatedproteininvolvedinmitoticspindleassembly
194979___________ +1.34 +1.150.0230.0240.0811215816344140416.3148_
*19754____________ -1.59 -1.490.0000.0000.0006075138271406996.3633_conservedhypotheticalprotein
195553___________ +1.31 +1.190.0020.0030.0091750622911209136.4123_conservedhypotheticalprotein
*194759___________ -4.45 -3.800.0000.0000.0005654141270291488826.4596_cytochrome-coxidasesubunitVa
*191237___________ +1.95 +2.080.0010.0050.0021622531631336776.5080_
*192678___________ +1.55 +1.500.0000.0020.0012613840394392356.5556_ser/thrproteinkinaseinmitosischeckpoint
*196265___________ -1.32 -1.490.0020.0120.0033632827510244606.6024_ribosomalprotein
193678___________ -1.15 -1.210.1390.2090.1311260451098621044536.6489_hypotheticalprotein
193102___________ +1.10 +1.030.3140.1560.7482624528878270826.6943_hypotheticalprotein
*196965___________ -2.58 -2.630.0000.0000.0003185961232821209466.7393_
*196424___________ +1.17 +1.200.0170.0280.0413732643834448606.7830_E2ubiquitin-conjugatingenzyme
*193281___________ +1.54 +1.370.0040.0090.0151450922410199356.8281_conservedhypotheticalprotein
197463___________ +1.05 +1.060.0830.0600.2291458215302155176.8714_
195874___________ +1.01 -1.010.8400.7840.6521210012162119526.9163_similartoopaquephaseproteinOP4
*191149___________ -1.30 -1.390.0060.0150.0153740328708268616.100__
*195614___________ -1.06 -1.200.0230.1960.0172651824966220486.727__
192227___________ +1.41 +1.310.0030.0050.0141400919751182896.1320_putativesulfatetransporter
193804___________ +1.19 +1.170.0060.0090.0301631119354191246.1867_
192530___________ +1.27 +1.120.0050.0050.0431240015719139446.2389_hypotheticalprotein
*195742___________ +1.49 +1.480.0020.0070.0051478822103218646.2923_orf6.2923
195125___________ +1.09 -1.120.3680.6390.2154518249022401956.3406_conservedhypotheticalprotein
19416____________ +1.21 +1.120.0100.0100.0661445017453161366.3899_hypotheticalprotein
*193506___________ +1.52 +1.570.0010.0040.0041789727163280616.4366_RNAlariatdebranchingenzyme
*192996___________ +1.25 +1.210.0030.0070.0082220827732268146.4869_involvedincellwallbiogenesisandarchitecture
196169___________ +1.05 +1.090.0150.0180.0581242713010135976.5330_conservedhypotheticalgene
19996____________ +1.19 +1.070.0290.0280.1031520718125162326.5802_hypotheticalprotein
*19397____________ -2.12 -2.340.0000.0010.0014185119754178886.6267_mitochondrialribosomalproteinofthelargesubunit
*19519____________ +1.51 +1.360.0010.0020.0041828027560249016.6731_weaklysimilartorDNAtranscriptionalactivatorUAF
196917___________ +1.27 +1.260.0010.0020.0021607920362202586.7181_conservedhypotheticalprotein
*196529___________ +2.15 +1.980.0000.0000.0003026864952599666.7631_ubiquitin-conjugatingenzyme
*197178___________ +1.57 +1.550.0000.0000.0004013463043621536.8078_20Sproteasomealpha-typesubunit
*197350___________ -2.91 -3.210.0000.0000.0003221531105981002376.8511_
*197602___________ -1.15 +1.010.0420.0180.6614806641680487356.8950_conservedhypotheticalprotein
19713____________ +1.17 +1.120.0230.0230.0901222314349136916.407__conservedhypotheticalprotein
19849____________ +1.16 +1.110.0260.0200.1481203013986133526.1043_
196234___________ +1.12 +1.110.0490.0400.1561429015948158546.1584_conservedhypotheticalprotein
191049___________ +1.20 +1.070.0430.0350.1491242814862133326.2131_8-oxo-dGTPase
192625___________ +1.10 +1.010.1960.1340.3511180113039118636.2649_hypotheticalprotein
*194317___________ -1.25 -1.020.0490.0260.3702434319547239686.3169_aldosereductase
194188___________ +1.09 +1.030.0850.0640.2191285214014132696.3645_nuclearimport|importinbetafamily
19748____________ +1.18 +1.110.0190.0160.1021370616186152826.4137_nuclearporeprotein
*194307___________ +1.21 +1.160.0170.0330.0341895122988220476.4612_Rad52inhibitor
196016___________ -1.04 +1.000.8860.7100.8081245411945124896.5095_
*192337___________ -1.32 -1.090.0040.0020.5503820628904349156.5571_high-affinitypermeaseforbasicaminoacids
196277___________ -1.05 -1.040.2750.4140.1911171011151112076.6036_conservedhypotheticalprotein
19433____________ -1.06 -1.010.6140.3690.8111484814055147126.6502_weakhomologytoKRE11,involvedinbiosyntheticpathwayforcellwallbeta-glucans
195177___________ +1.40 +1.320.0010.0030.0061621622700213606.6959_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*193997___________ -2.00 -1.500.0000.0000.001170165885042011362366.7410_alcoholdehydrogenase1
196407___________ +1.08 +1.010.3650.1820.8291504116291151556.7847_zincfingerprotein
195306___________ -1.06 -1.070.1620.3800.1061455213675136156.8295_
*197479___________ +1.53 +1.630.0000.0010.0002561839132417626.8731_neutraltrehalase(alpha,alpha-trehalase)
193787___________ -1.06 -1.070.0600.2680.0421174911066109746.153__
195518___________ +1.29 +1.200.0060.0100.0281337417280160536.745__
191609___________ +1.59 +1.400.0030.0060.0141371421840192436.1340_
193201___________ +1.21 +1.160.0050.0060.0311263215245146786.1884_amatinglocusregulatoryprotein
194574___________ +1.25 +1.210.0080.0100.0381290416117155716.2402_
62938____________ +1.19 +1.110.0100.0100.0591250714844138346.2938_
192185___________ +1.27 +1.160.0060.0060.0601290216381149676.3421_Nopsevenassociated|ribosomebiogenesis
*192507___________ +1.43 +1.250.0010.0010.0042162030979270186.3912_actin-relatedprotein
*191799___________ -1.51 -1.580.0030.0080.0095333435283337616.4378_
191321___________ +1.09 +1.190.0130.0780.0141376915063164076.4884_
191578___________ -1.14 -1.100.0150.0350.0271161410194105916.5342_processingofpre-rRNAto18Sand5.8SrRNA
196366___________ -1.24 -1.170.0010.0030.005117409455100596.5818_hypotheticalprotein
195094___________ -1.19 -1.120.0090.0210.020116749831104696.6282_ubiquitin-mediatedproteindegradation
19535____________ -1.14 -1.200.0630.3880.038119461045099396.6747_hypotheticalserine-richprotein
193298___________ -1.23 -1.140.0100.0290.019117509522103026.7194_
196515___________ -1.15 -1.150.0060.0230.0101174610188102346.7645_heatshockprotein90
197190___________ -1.19 -1.110.0080.0290.0141283610821115956.8091_
197364___________ -1.19 -1.140.0070.0190.016118309954103346.8524_flavin-containingmonooxygenase
197615___________ -1.19 -1.160.0060.0170.011116569754100606.8963_targetingcomplex(TRAPP)componentinvolvedinERtoGolgimembranetraffic
6424_____________ +1.36 +1.190.0040.0050.0231288017557153316.424__
191442___________ +1.32 +1.230.0040.0060.0271276016820157466.1059_
195063___________ +1.46 +1.340.0020.0050.0081514622048202986.1609_
191077___________ +1.31 +1.100.0060.0060.0751300017009142946.2146_
191774___________ +1.09 +1.050.0610.0380.2721345314704140716.2663_
1972_____________ +1.03 -1.020.4300.9270.2302508825949246956.3182_copperuptaketransporter
19762____________ +1.12 +1.090.0250.0210.1161255614113136916.3662_sphingomyelinphosphodiesterase
*191687___________ +1.64 +1.770.0010.0050.0032018233080357796.4152_RNAhelicaseinvolvedinspliceosomedisassembly
*195702___________ +1.33 +1.180.0110.0170.0332214929399261206.4633_
196132___________ -1.04 -1.110.0650.2750.0452358822735212006.5113_hypotheticalprotein
1923223__________ -1.02 -1.120.0330.1120.0342441623902218366.5585_NA
*194941___________ +1.57 +1.360.0040.0070.0222204634587300096.6049_basichelix-loop-helixtranscriptionfactor
*196621___________ +1.67 +1.540.0010.0030.0042032633874313886.6519_
195164___________ -1.05 +1.060.8190.6230.7632761226321291596.6972_alpha-1,6-mannosyltransferase
*194010___________ +1.34 +1.330.0010.0030.0021965026379261666.7423_componentofPab1p-stimulatedpoly(A)ribonuclease
196390___________ +1.09 +1.040.1120.0510.6131185912883123646.7864_hypotheticalprotein
195320___________ +1.31 +1.210.0070.0110.0231579920682190696.8309_negativeregulatorofcts1expression
197491___________ -1.02 -1.070.4360.7920.2431478214426138796.8743_regulationofmitochondrialnetwork
192430___________ +1.40 +1.200.0020.0030.0151450120352174406.169__
191996___________ +1.30 +1.250.0030.0060.0131277416558159366.766__
61356____________ +1.33 +1.230.0030.0050.0171353517956166066.1356_
19853____________ +1.22 +1.160.0400.1160.0411826922328211146.1902_Gpi-anchoredasparticprotease
*194368___________ +2.03 +2.020.0000.0010.0021477129986298756.2421_
*194490___________ +1.34 +1.400.0080.0260.0143796350834530146.2951_ribosomalproteinL17B
191829___________ +1.28 +1.160.0040.0050.0451383417703160596.3436_
196020___________ +1.35 +1.200.0020.0030.0231321917877158286.3924_involvedinautophagocytosisduringstarvation
*193203___________ +1.33 +1.230.0030.0050.0161868024800228936.4396_F-boxprotein:endocyticmembranetraffic,recycling
194788___________ +1.09 +1.210.2310.5040.1384920253672594616.4898_N-acetyl-gamma-glutamyl-phosphatereductaseandacetylglutamatekinase|N-acetyl-gamma-glutamyl-phosphatereductaseandacetylglutamatekinase|acetylglutamatekinaseandacetylglutamyl-phosphatereductase
*191404___________ +1.20 +1.180.0050.0200.0092045224447242186.5357_tRNAdihydrouridinesynthase
196382___________ +1.24 +1.120.0230.0200.1131299916065145186.5832_
*195077___________ -1.95 -1.960.0000.0010.00112718465366649896.6299_hypotheticalprotein
*19548____________ +2.88 +2.300.0000.0000.0002528972913580486.6760_septininvolvedincytokinesis,cellwallorganization,conjugation,andcelldivision
*193311___________ +1.22 +1.090.0200.0110.3442193826704239406.7206_oxidoreductase
196501___________ +1.09 +1.100.0350.0290.1361281113936140746.7659_
197203___________ -1.07 -1.090.0650.0740.1172151520047196696.8103_mitochondriallargeribosomalsubunit
197376___________ +1.06 +1.070.1190.0980.2221230813005131746.8536_hypotheticalprotein
197629___________ +1.08 +1.050.1090.0600.4041280213787135006.8976_
19632____________ -1.00 -1.000.5070.4900.3961360813583135646.443__hypotheticalprotein
191593___________ +1.38 +1.210.0020.0030.0171520320928184506.1071_ser/thrproteinkinase|glycogensynthasekinase3
194880___________ +1.11 +1.020.3840.2050.7171206213365122616.1625_hypotheticalprotein
191273___________ -1.01 -1.020.1230.0990.2311505614834147806.2165_prefoldinsubunit4
191240___________ +1.12 +1.060.0560.0340.2801257514127132686.2679_
193213___________ +1.05 +1.040.2790.1390.7061264213263131246.3195_
195220___________ +1.05 +1.040.2130.1550.3331243613078129226.3681_RNAEXonuclease;memberof3'->5'exonucleasefamily
*191378___________ +1.46 +1.570.0010.0030.0031551122647243516.4165_
193548___________ +1.07 +1.060.0960.0760.2151492215928157986.4653_conservedhypotheticalmembraneprotein
196227___________ +1.05 +1.000.2640.1220.8571195912554119946.5129_potentialC2H2Zincfingerdomain
191939___________ +1.08 +1.070.0500.0600.0961429215380152916.5600_conservedhypotheticalprotien
194168___________ -1.01 -1.030.2360.1270.5521200511930116566.6062_
196636___________ +1.04 +1.000.3240.1530.9381194912463119856.6533_conservedhypotheticalprotein
1968332__________ -1.02 -1.040.0850.3660.0521511414774144956.6985_NA
194023___________ +1.03 +1.150.4950.6630.3125925060952679266.7436_mitochondrialribosomalsmallsubunitprotein
194582___________ +1.09 +1.020.1060.0450.7981291314118131746.7881_3'->5'exoribonucleaseinvolvedinrRNAprocessing|superkiller
*195334___________ -1.42 -1.430.0040.0100.0104325830457301656.8323_Zincfingercontainingprotein
*197504___________ +1.92 +2.550.0000.0000.0002781853458710726.8756_conservedhypotheticalprotein
19508____________ -1.08 -1.100.0350.1170.0351221611279110686.183__
191624___________ +1.21 +1.130.0090.0090.0681261915239142026.786__
1973_____________ +1.39 +1.200.0020.0030.0391393419392167216.1372_
*193930___________ +1.36 +1.140.0040.0040.0722374732216271686.1916_putativeubiquitincarboxyl-terminalhydrolase-likeprotein
195230___________ -1.16 -1.330.0130.0460.0182489321493187616.2438_40SribosomalproteinS9,mitochondrialPRECURSOR
194415___________ +1.24 +1.120.0080.0070.0841476818314166066.2967_hypotheticalprotein
195207___________ +1.31 +1.200.0030.0050.0141364517882163296.3450_diphthaminesynthasesubunit
195295___________ +1.09 +1.040.0580.0250.7321684818282175506.3939_conservedhypotheticalprotein
*194046___________ +1.23 +1.180.0080.0130.0273060137769361226.4412_conservedhypotheticalprotein
195731___________ -1.14 -1.100.0150.0240.0401154610120104626.4910_phenylacrylicaciddecarboxylase
192137___________ -1.11 -1.110.0200.0600.0261159410481104196.5371_conservedhypotheticalprotein
193881___________ -1.20 -1.150.0510.0320.2661283210689111816.5851_
194391___________ -1.17 -1.140.0070.0190.016116949987102986.6316_hypotheticalprotein
196665___________ -1.18 -1.120.0370.0690.055115469802103386.6775_
19336____________ -1.16 -1.150.0040.0160.0081225610563106556.7220_mitochondrialmatrixiron-sulfurprotein
195270___________ -1.18 -1.110.0110.0230.025115549810103996.7672_conservedhypotheticalprotein
197215___________ -1.13 -1.120.0080.0310.0131167410333104666.8115_conservedhypotheticalprotein,possiblyU3snoRNPprotein
197388___________ -1.15 -1.090.0230.0320.0581225710678112806.8548_memberoftheHOG1MAPkinasecascade|tyrosineproteinkinaseoftheMAPkinasekinasefamily
197644___________ -1.17 -1.120.0150.0380.0271200410293107286.8992_ubiquitin-proteinligase;AnaphasePromotingComplex
*194689___________ +1.67 +1.430.0010.0020.0041499624971213866.461__hypotheticalprotein
191606___________ +1.39 +1.330.0060.0120.0161274617732170056.1087_hypotheticalprotein
*191671___________ +1.56 +1.500.0000.0010.0012407037602360206.1639_cellwallprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194731___________ +1.24 +1.090.0160.0120.1341242515379135076.2184_
193154___________ +1.02 -1.020.5210.5750.3661868719049182916.2694_
19470____________ +1.13 +1.070.0170.0150.0931406615831151016.3210_
*19683____________ -2.76 -3.020.0000.0000.00011501841692380936.3696_adenylatekinase
195486___________ +1.31 +1.400.0090.0240.0191277116667179306.4180_subunitofpolyadenylationfactorI
195491___________ +1.07 +1.060.0990.0940.1751243313274131526.4666_hypotheticalprotein
193904___________ +1.05 +1.060.2730.2030.3621209212680127586.5144_hypotheticalprotein
191852___________ -1.03 -1.070.1930.1080.4812294322282214816.5618_
194182___________ +1.03 -1.010.4830.2550.9181374814182135846.6076_weaksimilarityto3-oxoacyl-[acyl-carrier-protein]reductase
*196649___________ +1.51 +1.490.0000.0010.0012509337792373166.6546_transcriptionfactorIIIB|RNApolymeraseIIItranscriptionfactor
196849___________ +1.34 +1.290.0010.0030.0051533020589198526.6998_transcriptionelongationfactor
194036___________ +1.02 +1.010.7010.4290.9832233522808225076.7450_
*194596___________ +1.69 +1.700.0010.0030.0021553226187264126.7895_hypotheticalprotein
*195350___________ +1.23 +1.200.0290.0390.0685121662866614786.8339_CTDkinase-Igammasubunit
*197518___________ +1.26 +1.300.0100.0270.0183358042144437506.8770_transcriptionalregulatorofnitrateassimilation
*1948_____________ +1.55 +1.370.0010.0020.0091564224275215056.202__RNasePsubunit
1988_____________ +1.06 +1.040.6360.9680.3872364625033245976.810__
191298___________ +1.33 +1.170.0040.0040.0321279216988149796.1389_
19553____________ +1.25 +1.170.0020.0040.0131255915720146716.1930_dityrosinetransporter
*191604___________ +1.50 +1.360.0040.0070.0191355020391184316.2452_
191109___________ -1.03 -1.060.2640.2180.3142330522536220426.2985_hypotheticalprotein
191112___________ +1.35 +1.160.0070.0060.0781204816312139486.3464_involvedinbud-siteselection
193764___________ +1.40 +1.280.0010.0040.0061503221105192656.3955_ERtoGolgitransportprotein(TRAPP)
195588___________ +1.05 +1.080.1270.0990.2421263013262136056.4430_conservedhypotheticalprotein
*191065___________ -2.51 -2.450.0000.0000.0006238602488912541876.4924_chaperoninoftheHSP70family
192154___________ -1.09 +1.010.8050.7270.6326498659392656136.5389_
*193130___________ +1.57 +1.640.0000.0010.0003334252452548056.5867_highlyconservedhypotheticalprotein
195122___________ +1.13 +1.080.0180.0150.1141305814818140976.6328_hypotheticalprotein
196681___________ +1.10 +1.080.0840.0690.1932315925559250696.6790_hypotheticalprotein
*19349____________ +1.44 +1.600.0000.0010.0002173631202348266.7233_regulatorofmitochondrialsynthesisofAtp6pandAtp8p
*195258___________ +1.59 +1.420.0010.0020.0021583925187224966.7684_conservedhypotheticalprotein
*197229___________ +1.70 +1.560.0040.0070.0191671828455260456.8130_
*197401___________ +1.58 +1.380.0010.0030.0071901730097261666.8561_chromatinremodelingcomplex
197661___________ +1.05 -1.000.2170.0960.9441234612951122866.9009_mitochondrialDNAhelicase
194225___________ +1.39 +1.230.0080.0110.0301462020360180006.484__
*194777___________ -1.11 -1.170.0440.0660.0733191728880273426.1104_
193146___________ +1.06 -1.020.2120.0940.9801223612945119996.1656_hypotheticalprotein
196246___________ -1.02 +1.030.6660.3970.9771790217555184216.2198_N-terminalacetyltransferase
193627___________ +1.18 +1.130.0420.0380.1251348115840152376.2712_conservedhypotheticalprotein
193937___________ +1.11 +1.030.1660.0890.4871312614591134746.3224_SporulationDeFiciency
196480___________ +1.05 +1.050.3760.2830.4201194612518125626.3714_vanadateresistanceproteinGog5
194503___________ +1.01 +1.010.9490.7900.9091678316892169666.4195_conservedhypotheticalprotein
192582___________ +1.37 +1.430.0020.0050.0051466020114209846.4683_highlyconservedhypotheticalprotein
19215____________ +1.10 +1.040.1390.0740.4531180212963122736.5159_
19325____________ +1.03 +1.100.1480.6350.0762392524708262066.5633_pre-mRNAcleavageandpolyadenylationspecificityfactor
192174___________ -1.03 -1.060.3750.6750.2151175811368110446.6089_DNA-repair|RecAhomolog
19669____________ +1.09 +1.020.1260.0590.5971196213000121816.6562_pheromone-regulatedmembraneprotein
*196861___________ +1.36 +1.360.0000.0020.0012060527944279886.7010_anaphase-promotingcomplex
*192092___________ -1.02 +1.290.0120.5450.0073838237635493226.7463_cystathioninebeta-lyase
*194610___________ +1.71 +1.440.0040.0060.0241276921772184336.7909_carboxypeptidaseyscS
195365___________ +1.01 +1.040.2820.1920.4121267112760131976.8355_conservedhypotheticalprotein
*197537___________ +1.75 +1.690.0010.0030.0051574227570266676.8787_
*196382___________ +1.67 +1.650.0010.0030.0051562526159257556.12___
198______________ +1.25 +1.190.0470.0250.3601266715887151186.506__hypotheticalprotein
19230____________ +1.10 +1.090.0300.0290.1031244113653135356.1121_
*191771___________ +1.64 +1.750.0010.0030.0031664427296290996.1677_cellcyclecontrolprotein
*196464___________ +2.27 +1.970.0000.0010.0021644337391324366.2213_
192713___________ +1.23 +1.110.0160.0170.0701738021313193276.2729_meiosis-specificmutShomolog
191727___________ +1.24 +1.210.0120.0140.0551284815884155696.3238_Ca2+-transportingP-typeATPase
*193089___________ -3.02 -3.070.0000.0000.00011913939406387926.3732_possiblyinvolvedinintramitochondrialsorting
*192341___________ -3.91 -5.900.0000.0000.00023379759777396496.4211_similaritytoproteinkinaseCinhibitor-I,histidinetriadnucleotide-bindingproteins
*192740___________ +1.74 +1.570.0020.0040.0061517226327237696.4696_
192418___________ -1.10 -1.180.0110.0710.0132786425388235266.5175_conservedhypotheticalprotein
*193972___________ +1.52 +1.490.0000.0010.0012041730977303936.5648_GolgiTransport
193417___________ +1.03 +1.020.4390.3420.4422673427570271706.6108_
*192772___________ +1.28 +1.100.0180.0170.0932757835361303356.6580_histonedeacetylase
191897___________ +1.16 +1.140.0170.0180.0691627818851185836.7023_conservedhypotheticalprotein
*192077___________ +1.75 +1.420.0010.0020.0062804249111398776.7478_hypotheticalzincfingerprotein
*194624___________ +1.35 +1.460.0030.0090.0091474019968215786.7923_Ty3transpositioneffector
*197286___________ +1.72 +2.120.0010.0040.0021583027176335996.8368_
196829___________ +1.06 -1.000.1390.0660.6071350214264134786.8802_proteinrequiredfortheexpressionofsubunit-9ofatpsynthase
Cacda2___________ -1.02 -1.040.7750.8530.537121961192711684Cacda2_
19230____________ +1.37 +1.200.0020.0030.0221249217055149756.218__
*191933___________ +1.71 +1.880.0010.0050.0031637927991308116.829__
*191977___________ -2.25 -2.510.0000.0000.00011469150902456716.1407_dihydrooratase
193516___________ -1.11 -1.010.1670.0960.4272368521355233496.1949_conservedhypotheticalprotein
*192156___________ -1.47 -1.590.0010.0050.0035530137610347756.2470_glucosamine-6-phosphatedeaminase
*191097___________ +12.68 +14.360.0000.0000.000535706792537694206.3000_agglutininlikeprotein4
*19133____________ -1.96 -1.670.0000.0010.0012306581177231383806.3481_hypotheticalprotein
*194251___________ +1.83 +1.700.0010.0020.0031482827206251636.3973_
*19308____________ -1.16 -1.190.0020.0090.0043641531445306976.4446_nitroguanidineresistance
*192846___________ -1.37 -1.150.0010.0010.0282974021763259416.4940_hypotheticalprotein
*196183___________ -1.98 -1.960.0000.0000.0007646438669390866.5404_mitochondrialproteinimportmachinerysubunit
*192263___________ -1.32 -1.490.0020.0070.0064577134780306766.5883_hypotheticalprotein
*195104___________ +1.43 +1.490.0010.0030.0025052072107751966.6346_protein-tyrosine-phosphatase
*196698___________ -1.62 -1.620.0000.0000.0003881423898239936.6807_asn-tRNAsynthetase
*194437___________ +1.30 +1.160.0070.0100.0322421831376281006.7249_ATPasecomponentofafoursubunitchromatinremodelingcomplex
195245___________ -1.10 -1.060.0860.0570.2643030727671286366.7697_ubiquitinligasebindingprotein
*197244___________ -4.38 -4.750.0000.0000.00013374230559281756.8144_conservedhypotheticalprotein
*197414___________ +1.41 +1.380.0010.0040.0032162230384297546.8576_
*197675___________ -5.88 -8.060.0000.0000.000775932131851962646.9022_
*192455___________ +1.15 +1.290.0220.0710.0273139636077406346.33___
*192848___________ +2.57 +2.570.0010.0030.0051380935545355536.525__
*19195____________ +1.33 +1.240.0010.0020.0042320330764288856.1144_hypotheticalprotein
194330___________ +1.13 +1.110.0160.0140.0961342215117148746.1693_
*193599___________ +2.50 +2.730.0000.0000.0002563564094699466.2229_
*193635___________ +2.28 +2.340.0000.0010.0002373654213556096.2749_
194330___________ +1.29 +1.180.0060.0080.0271482419121174266.3257_
*19847____________ +3.90 +4.240.0000.0000.0002158784238914736.3747_mitochondrialinnermembraneprotease
*194893___________ +1.77 +1.840.0000.0000.000576561019431060916.4229_conservedhypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*194658___________ +1.56 +1.790.0010.0030.0012763743097493506.4709_zinc-fingerproteinwithcoiledcoildomain
*194297___________ +1.97 +2.300.0000.0020.0011984439113456556.5189_
*192626___________ +1.40 +1.480.0080.0160.0205143372160762576.5661_
*192901___________ +1.31 +1.730.0020.0150.0041534520041265316.6122_
192760___________ +1.10 +1.070.0400.0330.1431292614176137866.6592_
*191883___________ +1.41 +1.430.0020.0040.0071789425143255136.7038_
*192065___________ +1.54 +1.350.0010.0020.0031702226299229656.7490_allantoinase|nitrogenandsulfurmetabolism
197011___________ +1.05 +1.030.3110.1470.8811297913689133526.7937_pre-rRNAprocessing
197301___________ +1.08 +1.060.0960.0500.4361357114683143706.8382_
196813___________ +1.08 +1.080.0570.0680.1061338314446144626.8818_hypotheticalprotein
Cafks1___________ -1.01 +1.020.8900.8660.694119321181712127Cafks1_
*195061___________ +1.59 +1.740.0000.0000.0003007447721524416.238__
191209___________ +1.18 +1.160.0070.0120.0261256814850145196.842__hypotheticalprotein
*194779___________ +1.81 +2.230.0000.0010.0011628329449362896.1423_
*191913___________ +1.08 +1.120.0360.1920.0282661728647298556.1966_hypotheticalprotein
194067___________ +1.18 +1.090.0180.0150.1071274515006138376.2485_hypotheticalprotein
*191246___________ +2.10 +2.420.0010.0030.0021905439953460296.3013_
*195182___________ +1.71 +1.850.0000.0010.0002691745990497426.3494_
*194349___________ +1.66 +2.110.0000.0020.0011680227916355166.3993_conservedhypotheticalprotein
195519___________ -1.03 -1.040.6870.6480.5143072629841294266.4461_glycinecleavageTprotein
*1924781__________ -2.21 -1.960.0000.0000.0004573302069482337076.4956_NA
*196203___________ +1.46 +1.370.0010.0020.0041816826506248386.5420_
192248___________ -1.20 -1.010.2210.0980.9184417436768438606.5898_acyl-CoAsterolacyltransferase
*192000___________ +1.31 +1.320.0020.0050.0051830423991240906.6360_requiredformitoticchromosomesegregationandmeioticrecombination
194116___________ +1.01 +1.020.9900.9260.9302171921961221626.6820_conservedhypotheticalprotein
*194449___________ -1.80 -1.750.0000.0000.00011873465802679316.7262_copperchaperoneinvolvedinlysinebiosynthesisandoxidativestressprotection
195231___________ -1.11 -1.110.0400.0720.0601971517833177516.7711_
*197258___________ -1.55 -1.300.0020.0020.0275888837894452956.8159_
*197433___________ +1.88 +2.090.0020.0080.0061516128526317386.8590_
*196000___________ +4.46 +5.760.0000.0000.000505862255972916146.9037_multidrugresistanceprotein|ABCtransporter
*194347___________ +2.93 +2.540.0000.0000.000475701393341205916.50___
*195181___________ +1.93 +1.910.0020.0050.0081576230397300596.547__histidinekinaseosmosensor
191803___________ +1.31 +1.180.0080.0100.0381272816614150736.1162_geranylgeranyltransferasebetasubunit
194697___________ +1.22 +1.120.0150.0120.1251424617364159356.1711_
*191392___________ -1.18 -1.320.0120.1330.0115143743693389026.2244_proteindisulfideisomerase
194220___________ -1.15 -1.280.0020.0260.0032416020958188966.2765_conservedhypotheticalprotein
*192857___________ +2.12 +2.280.0010.0030.0031534432568349766.3274_
193459___________ +1.38 +1.250.0040.0060.0221588021989198596.3762_serine/threonine/tyrosineproteinkinaseinvolvedinchromosomesegregation
191282___________ -1.01 -1.030.6710.9660.4181888018642182636.4243_cyclin-dependentkinasesregulatorysubunit
19576____________ +1.19 +1.170.0220.0650.0291548218449181566.4726_kinetochorecomponent
194283___________ +1.16 +1.090.0330.0370.0871597218448174126.5203_relatedtotranslationinitiationfactorandCOP9/signalosomesubunit
196138___________ -1.01 +1.040.5950.9200.3551293412838134276.5676_ferricreductasetransmembranecomponent
192889___________ +1.09 +1.080.0270.0310.0781282013984138426.6133_conservedhypotheticalprotein
*194240___________ -1.54 -1.840.0000.0000.0005593036332304046.6605_involvedinmanganesehomeostasis
*67051____________ +3.13 +2.580.0000.0000.0002915491167752926.7051_
*193810___________ +1.27 +1.200.0060.0060.0544358755177523896.7505_methylenetetrahydrofolatedehydrogenase|NAD-dependent5,10-methylenetetrahydrafolatedehydrogenase|NAD-dependent5,10-methylenetetrahydrafolatedehydrogenase|methylenetetrahydrofolatedehydrogenase(NAD+)
197024___________ +1.05 +1.080.0450.0670.0741487415544161076.7950_hypotheticalprotein
*197314___________ +1.32 +1.520.0000.0020.0011974725992299916.8395_cysteinedioxygenase
*196801___________ +2.06 +2.110.0150.0460.0221686034693355916.8830_histonedeacetylase;transcriptionmodifier
Caskn1___________ -1.04 +1.040.6170.3770.789122311175912681Caskn1_
194357___________ +1.28 +1.240.0020.0040.0081710921975212006.252__
*191189___________ +3.84 +3.320.0000.0000.000440231691381461286.861__
*19119____________ +1.24 +1.100.0260.0470.0461404017404155046.1442_
*192990___________ +4.27 +3.590.0000.0010.0011830978199657326.1982_glucan1,3-beta-glucosidase
*1996_____________ +1.82 +2.260.0000.0030.0013546864702801996.2499_
193648___________ -1.05 -1.000.6660.4170.8152470023588246376.3029_putativetranscriptionalco-activator
193964___________ +1.20 +1.130.0100.0120.0411955423527221106.3507_transcriptionfactor,containsaPHDfingermotif
*192942___________ +2.66 +2.500.0000.0000.0003067781558768266.4006_dicarboxylicaminoacidpermease
*193178___________ +1.80 +1.820.0000.0020.0012206939787401816.4476_
*192465___________ +1.34 +1.300.0060.0120.0172725036558353456.4971_
196283___________ +1.14 +1.100.0330.0330.1011399815902153616.5433_mitochondrialmatrixprotein
*194931___________ +1.78 +1.810.0000.0010.0013161256332573346.5911_cysteinyl-tRNAsynthetase
*191412___________ -1.22 -1.220.0030.0060.0086856156345560706.6381_hypotheticalprotein
194099___________ -1.05 +1.170.6140.9390.3693592353433164213456.6837_extracellularsulfitereductase
*19900____________ +5.00 +6.470.0000.0000.000229581147661484666.7275_
196978___________ +1.08 +1.110.0180.0280.0431303314141144656.7724_hypotheticalprotein
*197274___________ +1.49 +1.430.0010.0030.0061621124125232046.8173_
197444___________ +1.23 +1.210.0020.0090.0041917023537232676.8604_conservedhypotheticalprotein
*195985___________ -1.16 -1.140.0060.0110.0193329328722292626.9052_polypeptideofanon-nativeactinbindingcomplex
*1958_____________ +1.50 +1.400.0030.0080.0081265019013177736.74___
19915____________ +1.36 +1.190.0030.0040.0241280917469151966.568__leucinerichrepeatprotein
19114____________ +1.24 +1.200.0080.0130.0261277215861153116.1182_hypotheticalprotein
19707____________ +1.11 +1.040.0830.0480.3452010622243209816.1727_componentoftheautophagicsystem
*193756___________ +1.46 +1.440.0040.0100.0101340919611193666.2262_DEADboxRNAhelicase
191148___________ +1.20 +1.130.0060.0090.0231227614675138996.2785_
193617___________ +1.27 +1.150.0020.0030.0191430018184164386.3287_smallGTPasethatmaybeinvolvedinthefunctionofthePho84phosphatetransporter
194361___________ +1.26 +1.160.0080.0090.0411267715978147186.3779_
192210___________ +1.32 +1.290.0010.0030.0071692822315219216.4255_
192119___________ +1.10 +1.100.0250.0330.0641845620310202616.4743_
194812___________ +1.02 +1.010.7570.5000.8691424214493143356.5218_holo-(acyl-carrierprotein)synthase|holo-ACPsynthase|4'-phosphopantetheinyltransferaseacpS
19590____________ +1.08 +1.010.1070.0520.5071535016647154666.5690_ABC-typenitrate/sulfonate/bicarbonatetransport
195832___________ +1.11 +1.130.0160.0270.0361538717139173756.6146_hypoxanthineguaninephosphoribosyltransferase
194223___________ +1.19 +1.080.0220.0230.0831283115285138466.6621_
*19501____________ +1.15 +1.190.0080.0310.0122806232333335276.7068_
193825___________ +1.00 -1.050.1790.6240.0942131621322202726.7520_proteaseinvolvedinrasanda-factorterminalproteolysis
197037___________ -1.06 -1.100.0260.1140.0251952218362177876.7963_essentialprotein,unknownfunction
197326___________ +1.12 +1.120.0140.0310.0261341714992150696.8407_conservedhypotheticalprotein
196788___________ +1.06 +1.150.0270.0290.0811252613324143816.8843_hypotheticalprotein
41894____________ +1.09 +1.070.0580.0560.1351347514623144554.1894_
19718____________ +1.23 +1.250.0030.0060.0091367016852170916.273__
196349___________ +1.31 +1.170.0050.0050.0451378118060161036.878__
192637___________ +1.11 +1.100.0230.0310.0581902021018208696.1458_involvedinmanganesehomeostasisandproteinprocessing
19247____________ +1.26 +1.200.0030.0040.0191471818511175946.1995_
194127___________ +1.37 +1.210.0010.0010.0051564821475188576.2515_
194525___________ +1.12 +1.080.0220.0210.0901362615214147716.3046_membraneproteinwithweakhomologytoNADH-ubiquinoneoxidoreductase
19636____________ +1.24 +1.150.0110.0110.0661272615778146046.3523_hypotheticalprotein
*194749___________ +1.31 +1.190.0090.0120.0361378817998164016.4019_hypotheticalmembraneprotein
*192830___________ -1.51 -1.400.0010.0010.0043400522547242736.4491_U3snoRNPprotein
*193476___________ +1.78 +1.610.0000.0000.0023452661318554766.4983_caseinkinaseI
196299___________ +1.11 +1.150.0070.0100.0281486416503170516.5449_ubiquitinactivatingenzyme

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
1931_____________ +1.04 +1.030.6870.4200.9141528515933157726.5926_
191426___________ +1.24 +1.110.0100.0090.0851543719105171706.6394_
*194088___________ -1.49 -1.340.0010.0010.0046161241226458306.6849_
19886____________ +1.08 +1.000.1580.0710.7352101122641210456.7290_
196990___________ -1.14 -1.160.0070.0180.0142198019346189246.7736_peptidyl-prolylcis-transisomeraseD|cyclophilinD
19938____________ -1.01 -1.020.2350.8650.1161679116573164536.8187_hypotheticalprotein
197456___________ +1.29 +1.180.0040.0050.0301374217781162566.8616_hypotheticalprotein
195971___________ +1.06 +1.040.1170.0520.6691380714627143546.9066_conservedhypotheticalprotein
*194546___________ +1.50 +1.520.0020.0040.0091609924206244886.97___
194395___________ +1.24 +1.190.0030.0070.0101533819096183106.590__
*191435___________ -1.68 -2.080.0000.0040.0013497302083511682646.1201_
191178___________ +1.04 +1.070.1190.1140.1871242812970133496.1743_
193954___________ +1.30 +1.200.0030.0060.0131301816973155956.2277_phosphatidylserinedecarboxylase
194346___________ +1.08 +1.060.0570.0400.2121227413206130166.2801_
193660___________ +1.29 +1.240.0030.0070.0091502719341186376.3301_hypotheticalprotein
195722___________ +1.10 +1.060.0550.0410.1871369815074145896.3797_DNA-bindingprotein
*192615___________ +1.27 +1.120.0020.0030.0132723434609304626.4270_ATP-bindingcassettetransporterfamilymember
*192103___________ +1.48 +1.380.0040.0080.0121907028249263306.4758_
194144___________ +1.02 -1.010.5900.3460.8291675417134165786.5235_
192983___________ -1.03 -1.030.5310.5400.3931657116101160456.5706_accessoryfactorassociatedwithRNApolymeraseII
192476___________ -1.02 +1.010.9200.8180.7781347313262136506.6159_
195802___________ +1.07 +1.060.1980.1630.2771579216934167156.6637_
19488____________ +1.11 +1.040.1500.0840.4312127423619220846.7083_nuclearmRNAexport,poly(A)+RNAbindingprotein
*193840___________ +1.47 +1.330.0020.0050.0102198332387292466.7535_DNApolymerasealphasuppressingproteinkinase
*195032___________ +1.23 +1.210.0160.0400.0272693373319293272216.7977_proteininvovledincontrolofDNAreplication
197340___________ +1.10 +1.040.0250.0120.4831333814691139016.8421_hypotheticalprotein
*196776___________ +1.47 +1.630.0030.0080.0081540922608251266.8856_
43011____________ +1.06 +1.070.6940.4640.7531220412900130404.3011_
*192135___________ +1.40 +1.210.0110.0090.1102372633124287976.287__
*193193___________ +1.66 +1.600.0010.0030.0031475024543235866.907__
192778___________ +1.34 +1.190.0050.0070.0311292817314154416.1475_conservedhypotheticalprotein
*191052___________ +6.11 +4.560.0000.0000.000253761551471157106.2008_histone2B
192749___________ +1.29 +1.170.0050.0070.0271305216887153276.2534_
*194799___________ +1.44 +1.420.0030.0060.0121423120544202336.3058_myb-relatedDNA-bindingproteinrequiredduringG2/Mtransition
*191500___________ +1.35 +1.290.0020.0050.0101594121451204926.3541_
*195101___________ +1.13 +1.060.0140.0110.1122809031744296946.4036_glucose-repressibleADHtranscriptionaleffector
*195636___________ -6.29 -5.340.0000.0000.00027736564406835192646.4505_repressedbyTUP1protein5
*194513___________ +1.49 +1.390.0040.0060.0181455421727201966.4997_
*193733___________ -5.20 -8.700.0000.0000.00029895357511343556.5462_
*19207____________ +1.36 +1.400.0030.0080.0091436419521200936.5942_
*191549___________ -1.31 -1.330.0040.0140.0093847629334289836.6407_hypotheticaltransmembraneprotein
*196713___________ +1.73 +1.800.0000.0010.0014696381170847286.6863_
19873____________ -1.13 -1.160.0110.0500.0142517322234216456.7304_hypotheticalprotein
*193012___________ -1.19 -1.180.0040.0120.0093127826312264816.7749_conservedhypotheticalprotein
*19951____________ +1.69 +1.370.0010.0010.0243485058821476326.8200_hypotheticalprotein
195393___________ -1.02 -1.060.3130.7210.1682373423187224836.8629_glutamatedecarboxylase
*195960___________ -1.54 -1.740.0010.0040.0013125342027161800036.9077_non-classicalproteinexportpathway
192116___________ +1.23 +1.220.0030.0070.0101616819889196856.118__N-acetyltransferaseforN-terminalmethionine
192360___________ +1.27 +1.200.0020.0030.0081484518866177576.610__
191830___________ +1.23 +1.180.0070.0100.0291268815598149926.1220_hypotheticalprotein
*194686___________ +1.29 +1.160.0140.0100.1531447618721168576.1766_
*193354___________ -2.54 -2.620.0000.0000.00011223444161428656.2294_40Sribosomalprotein
194405___________ +1.27 +1.120.0070.0070.0531260316066141716.2823_tyrosinephosphatase
195038___________ +1.39 +1.200.0020.0030.0111525521158183726.3315_tRNA(guanosine-2'-O-)-methyltransferase
192560___________ +1.24 +1.150.0070.0090.0391323316438152526.3810_
*193538___________ +1.42 +1.510.0030.0080.0101242117632187326.4284_ferricreductase
195616___________ +1.18 +1.110.0080.0090.0481236014646136826.4775_
193863___________ +1.08 +1.060.0650.0490.2031314814253139836.5253_hypotheticalprotein
*191253___________ +1.34 +1.300.0010.0030.0032219129676288706.5720_myc-familytranscriptionfactor
192494___________ +1.05 +1.010.3640.1760.9461395614665140636.6174_
192964___________ +1.22 +1.140.0040.0060.0251607919658182646.6652_MemberofRSCcomplex,whichremodelsthestructureofchromatin
191474___________ +1.19 +1.130.0140.0120.0921431017094161416.7098_
*196565___________ -1.90 -1.870.0010.0020.0023574918858190816.7552_
*195019___________ +1.35 +1.330.0080.0100.0321758023705232986.7991_
197119___________ +1.02 -1.010.8940.8170.7251859819052184506.8433_
*196763___________ +2.45 +2.610.0000.0010.000522031281131364916.8868_
43032____________ +1.07 +1.060.0660.0710.1261177312595125004.3032_
*191277___________ +1.72 +1.590.0020.0040.0101411824251224426.303__
193952___________ +1.32 +1.220.0040.0060.0271267016680154486.928__
192805___________ +1.27 +1.170.0030.0050.0251306816635153086.1492_
194464___________ +1.16 +1.130.0150.0180.0571292414986146286.2031_lowhomologytotRNAsplicingendonuclease
*19802____________ +1.50 +1.340.0020.0030.0151426321463191396.2549_
194553___________ +1.19 +1.110.0070.0070.0571653619717183676.3073_
192458___________ +1.16 +1.160.0040.0120.0101634218941188826.3559_
193925___________ +1.19 +1.110.0140.0110.1341271415081140536.4051_hypotheticalprotein
195651___________ +1.36 +1.240.0010.0030.0101554421123192876.4520_
194209___________ +1.13 +1.120.0100.0190.0271568817721175436.5012_ubiquitin-activatingenzyme
193748___________ +1.14 +1.080.0220.0260.0681213513784130556.5477_
195140___________ +1.06 +1.030.1570.1260.2581339014245137276.5958_hypotheticalgenefamily
*191564___________ -2.33 -1.950.0000.0000.0027324331409375486.6421_conservedhypotheticalmembraneprotein
196727___________ -1.08 -1.050.0470.0950.0592268621081215986.6876_ribosyltransferaseofinitiatortRNAmethionine
196931___________ +1.02 -1.030.5640.6880.3671764018007170816.7318_
193026___________ -1.29 -1.220.0030.0060.0142229417320183406.7763_mitochondrialprocessingprotease
19966____________ +1.09 +1.010.2780.1310.8151523416610153556.8215_dihydrouridinesynthase
*195409___________ +1.46 +1.440.0010.0020.0022035829676293256.8645_putativetranslationinitiationfactor
195947___________ +1.11 +1.090.0550.0490.1461442715963156606.9093_
*195065___________ +1.35 +1.240.0030.0060.0141937426128240946.133__
*193158___________ +1.49 +1.330.0010.0030.0071653524598219966.641__
193172___________ +1.24 +1.150.0050.0070.0271344416697155046.1239_hypotheticalprotein
193289___________ +1.01 -1.100.2460.5340.1443546835881323906.1779_hypotheticalprotein
193852___________ +1.10 +1.210.0050.0170.0081300814284157666.2314_
194965___________ +1.05 +1.080.0680.0890.1041208812703130226.2840_hypotheticalprotein
*19704____________ -1.66 -1.900.0000.0010.00012698476597668106.3328_conservedhypotheticalprotein
195287___________ +1.07 +1.030.0990.0620.3041563816711160436.3826_SET-domainprotein
*19295____________ +1.30 +1.180.0040.0060.0202473532032292706.4299_
*195631___________ +1.11 +1.130.0310.0440.0661587017626178836.4790_hypotheticalprotein
*196548___________ -1.23 -1.420.0010.0130.0013637429525256926.5266_iron-sulfurclusternifU-like
191266___________ +1.03 +1.030.2010.1130.4781232212660127276.5733_hypotheticalprotein
*195767___________ +1.45 +1.530.0010.0030.0031761025567268606.6192_
192952___________ +1.05 +1.040.3050.2330.3681625717095169326.6664_exo-1,3-beta-glucanase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*191460___________ +2.24 +2.280.0000.0000.0003801285074865796.7113_glutamine-dependentNAD(+)synthetase
196580___________ +1.20 +1.090.0100.0100.0651585619048173246.7568_hypotheticalprotein
*195005___________ -1.34 -2.110.0000.0250.0003540332639781677276.8004_osmoticgrowthprotein
*197106___________ +3.37 +4.920.0000.0020.0011452048949714316.8447_membraneproteininvolvedinvacuolarproteinsorting
*196748___________ +1.58 +1.490.0010.0030.0033408553781507856.8883_translationinitiationfactor
42795f--1________ +1.08 +1.090.0320.0310.1031231413262134274.2795f
*19362____________ -1.09 -1.290.0100.2860.0072443542239271896046.322__transcriptionalactivation
19182____________ +1.34 +1.230.0030.0070.0121341617997164516.944__
*192655___________ +1.57 +1.410.0000.0000.0014936277626694446.1509_cellcyclearrestprotein
*193586___________ +2.32 +2.270.0000.0000.0002362054913535416.2045_
*19111____________ +3.06 +2.570.0000.0010.0011421943576365646.2564_
63087____________ +1.10 +1.110.0200.0270.0581288914124142596.3087_
*192210___________ +1.79 +1.560.0010.0030.0061514827049235556.3574_hypotheticalprotein
194672___________ +1.16 +1.130.0130.0100.1341270614790143536.4064_hypotheticalprotein
*194372___________ +3.60 +3.220.0000.0000.00030444109725980696.4537_probablemembranetransportprotein
193329___________ +1.01 +1.010.8030.6490.6934897249490495806.5025_sphingosine-1-phosphatephosphatase
192704___________ +1.17 +1.090.0200.0150.1271252414691136686.5492_hypotheticalprotein
192033___________ +1.14 +1.060.0230.0260.0721514217332161176.5972_hypotheticalprotein
*191637___________ +1.24 +1.210.0050.0160.0095337766172646306.6435_conservedhypotheticalprotein
*195651___________ +2.25 +2.450.0000.0000.0002578457984631136.6892_
*196947___________ -1.68 -1.730.0000.0030.00116227996362940556.7333_glutathioneS-transferase
193041___________ +1.30 +1.360.0010.0050.0031637521266223186.7778_conservedhypotheticalproteinwithsimilaritytoROD1
19980____________ -1.09 -1.090.0530.0520.1273861335409354336.8229_methionineN(alpha)-acetyltransferase
*195423___________ +1.52 +1.460.0000.0010.0021938029433283736.8659_hypotheticalprotein
195930___________ +1.01 +1.020.4340.2740.5731235212531125806.9107_nuclearporeprotein
19162____________ +1.30 +1.190.0030.0050.0181384618009164446.147__hypotheticalprotein
*196257___________ +1.80 +1.310.0020.0030.0191389225052181916.655__
192647___________ +1.37 +1.220.0030.0040.0161465820138178536.1256_
*193388___________ +1.23 +1.140.0120.0090.1521417417494161436.1802_
*191650___________ -2.20 -2.010.0000.0000.0005958227064296006.2330_
*19457____________ +1.30 +1.620.0040.0150.0091472819216238876.2858_
*194645___________ +2.18 +2.070.0000.0010.0011794939173371846.3343_
194882___________ +1.11 +1.020.3780.1990.7374523650085463326.3841_RNApolymeraseIITFIIEsmallunit
*194475___________ +1.39 +1.440.0000.0030.0012501934749361116.4312_putativemannosyltransferase
19280____________ +1.16 +1.100.0090.0110.0441320015335145246.4809_hypotheticalprotein
193010___________ +1.11 +1.160.0410.0550.0801906821135220936.5279_lipoatebiosynthesisprotein
*191670___________ +1.30 +1.300.0010.0030.0026935890281903976.5745_involvedinintegralmembraneproteintrafficking
*196596___________ -1.75 -1.260.0030.0030.0599316853252740386.6208_esterase
*194531___________ +3.55 +4.070.0000.0000.00026482940121078066.6677_ATP-dependentABCtransporter
*191446___________ +2.01 +1.860.0000.0010.0014315886927802006.7127_G2/mitotic-specificcyclin|B-typecyclin
*196036___________ +1.25 +1.420.0020.0100.0032024025270287736.7580_partofcomplexthatcatalysesguanylnucleotideexchangeonYpt6p
194991___________ +1.27 +1.250.0050.0100.0171566019944196296.8019_
197093___________ +1.07 +1.060.1670.0850.5471696918237179576.8460_sugartransporter-likeprotein
197548___________ +1.14 +1.260.0050.0240.0071736019756218696.8896_DNA-directedRNApolymeraseIIholoenzymeandkornbergsmediator
42858f___________ +1.02 +1.050.2140.2760.1861188312135124894.2858f
194468___________ -1.13 -1.180.1630.1370.2473865934177327656.336__succinatedehydrogenasemembraneanchorsubunit
191329___________ +1.40 +1.240.0030.0050.0121390819436173006.960__hypotheticalprotein
*192815___________ +1.24 +1.280.0010.0040.0022068325552264116.1523_pantothenatesynthase
19374____________ +1.18 +1.110.0080.0090.0421261514892139586.2064_
*193370___________ +1.65 +1.740.0010.0040.0031512824952263696.2581_
*191311___________ +1.29 +1.290.0010.0030.0022004425778258726.3102_relatedtoyeastsporulationprotein
192757___________ +1.30 +1.290.0020.0050.0091520319816196496.3589_conservedhypotheticalprotein
*192361___________ +1.23 +1.190.0170.0170.0761474118125175086.4079_
*1954_____________ +4.21 +5.590.0000.0000.00022506947401258346.4552_RepressedinHyphalDevelopment|familyofconservedproteinofunknownfunction
*191966___________ +1.28 +1.370.0000.0030.0012081826646284266.5038_budsiteselectionprotein
*196316___________ +1.22 +1.390.0010.0090.0014673957137647426.5509_integralmembraneprotein
*192045___________ +1.51 +1.570.0000.0000.0002191633183343926.5984_ERmembraneprotein
*191621___________ +1.18 +1.280.0020.0140.0033526741571450736.6451_guaninenucleotide-bindingregulatoryprotein
*195664___________ +1.12 +1.120.0140.0310.0272279525421256416.6904_conservedhypotheticalprotein
194858___________ +1.04 +1.070.0940.0740.2121240612882132816.7352_vacuolarproteinsorting
*193053___________ -5.40 -4.470.0000.0000.000509882943681139686.7790_hypotheticalprotein
193242___________ +1.05 +1.040.1140.1710.1191335413957138886.8242_transcriptioninitiationfactorTFIIDsubunit
*195436___________ +1.29 +1.400.0060.0090.0221441118625201046.8671_
195915___________ +1.03 +1.070.1810.2740.1511296013333138676.9121_
1944_____________ +1.21 +1.130.0090.0100.0461272115348143886.9____ReCYcling
192720___________ +1.13 +1.100.0160.0180.0631255814249138206.675__
*192850___________ +2.46 +3.170.0000.0020.0011809444424573426.1274_
*192886___________ +1.88 +1.790.0000.0010.0012359544297421616.1819_MAPkinaseinvolvedinpheromonesignaltransduction
*193893___________ +1.84 +1.840.0000.0000.0005002691980918106.2346_SolubleCellWallprotein
193703___________ +1.38 +1.320.0040.0070.0141420619544187296.2874_
196496___________ +1.34 +1.340.0020.0050.0081448019343193956.3361_TRAPPsubunit;Golgitrafficking
*192393___________ +1.26 +1.220.0040.0110.0122833035731345176.3855_polyadenylationfactorsubunit
193404___________ -1.00 -1.050.3440.7320.1871563615611149226.4328_
*19606____________ +1.22 +1.070.0210.0140.1983659744766389936.4825_conservedhypotheticalprotein
191360___________ +1.11 +1.120.0260.0350.0641925621303216496.5292_conservedhypotheticalprotein
*193569___________ +1.30 +1.170.0150.0140.0821433818632167896.5759_
*196610___________ +1.42 +1.380.0030.0050.0121484121063204556.6223_
*194543___________ -2.28 -3.060.0000.0000.00012405854405405626.6689_succinate-semialdehydedehydrogenase|involvedinutilizationofGABAasanitrogensource
196877___________ +1.01 +1.050.3190.4080.2351204212190126816.7142_
*196049___________ +1.50 +1.650.0010.0040.0021414021240233236.7594_
*197136___________ +1.64 +1.720.0010.0040.0041946431878334146.8037_
*197079___________ +1.32 +1.130.0040.0040.0472708935637306986.8474_cellcycleregulatedproteinrequiredforaxialbudformation|3-isopropylmalatedehydrogenase
*197561___________ +3.18 +3.310.0000.0000.000329111046821089996.8910_
43070____________ +1.04 +1.050.1770.1170.3521235412810130294.3070_
194258___________ +1.40 +1.240.0020.0030.0081472620627183086.357__componentofapre-mRNApolyadenylationfactor
*195121___________ +1.93 +1.600.0010.0020.0041581130489253746.982__
192455___________ +1.11 +1.080.0340.0330.1041217213567131916.1539_highlyconservedhypotheticalprotein
*194732___________ +1.90 +1.660.0000.0010.0022108439998350996.2083_
19135____________ +1.27 +1.180.0040.0090.0161301416577153286.2599_
191708___________ +1.18 +1.110.0160.0160.0731229714522135936.3119_hypotheticalproteinofconservedsyntenywithrelatedS.cerevisiaeprotein
192787___________ +1.23 +1.190.0020.0040.0101275615685151566.3604_
*191756___________ +1.74 +1.680.0010.0020.0035354393085902006.4093_glycerol-3-phosphatedehydrogenase
*195686___________ -3.01 -3.300.0000.0000.0006467621490196036.4565_
65052____________ +1.41 +1.420.0020.0040.0091528221500217726.5052_
*196336___________ +1.17 +1.160.0110.0220.0262467028797285596.5525_
196459___________ +1.27 +1.270.0020.0040.0071819723123231056.6000_diacylglycerolpyrophosphatephosphatase
*193441___________ +1.53 +1.270.0130.0150.0531106991698441411106.6464_putativetransporter
*195678___________ +1.71 +1.840.0010.0030.0012307839471424346.6918_conservedhypotheticalprotein|similartodiphteriatoxinresistanceprotein
*194844___________ +1.65 +1.600.0000.0010.0012364438981377676.7367_argininemethyltransferase-interactingRINGfingerprotein
*193065___________ -1.16 -1.310.0030.0250.0033397429163259336.7802_D-aminoacidoxidase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*193255___________ +1.46 +1.620.0020.0050.0041430520940231976.8255_hypotheticalprotein
*195449___________ +1.24 +1.270.0020.0040.0104175851605529166.8684_
195903___________ +1.08 +1.030.2340.1440.4391219213135125886.9134_similartoB-chainsoftheinsulin-relatedsuperfamily|maybeinvolvedinbudsiteselection
19815____________ +1.25 +1.180.0060.0080.0251297616177153436.45___
*19254____________ +2.23 +2.030.0000.0000.0002679059764543986.691__hypotheticalprotein
*191991___________ +1.37 +1.300.0000.0010.0022695636800350596.1291_memberofthemajorfacilitatorsuperfamily
193722___________ +1.55 +1.380.0020.0040.0111352520955186206.1836_
*19265____________ +1.86 +1.880.0010.0030.0051536428513288256.2360_hypotheticalprotein
193367___________ +1.11 +1.030.1020.0570.3821903121054196326.2893_
192520___________ +1.05 -1.070.3200.7160.1731935320351181626.3376_
193694___________ +1.28 +1.220.0030.0050.0141388617708169416.3872_hypotheticalprotein
*192200___________ +1.63 +1.610.0010.0030.0031665027158268596.4341_vesicularintegral-membraneproteinVIP36-like
*191721___________ -1.77 -1.540.0000.0010.0025341030108347136.4839_conservedhypotheticalprotein
193708___________ +1.16 +1.160.0100.0150.0331269814740147086.5306_secretedasparticproteinase
196344___________ -1.14 -1.090.0510.0790.0773569431380327136.5773_ribokinase
*196102___________ -1.25 -1.290.0210.0270.05710719585414828326.6239_ATF/CREBactivator
*19813____________ +1.82 +2.220.0000.0020.0004054373943900026.6704_hypotheticalprotein
196893___________ +1.26 +1.210.0040.0100.0101994125157241256.7157_
*196062___________ -2.38 -2.780.0000.0010.00111093846581398856.7606_conservedhypotheticalprotein
197151___________ +1.14 +1.120.0120.0200.0351341015297150476.8051_hypotheticalprotein
*197065___________ +1.36 +1.340.0010.0030.0022317431457310996.8488_conservedhypotheticalprotein
197576___________ +1.02 +1.050.4750.3680.4641457014815153096.8924_probablemethyltransferase
p18a=p19_________ +1.14 +1.100.0100.0090.074143331633815795p18a=p1
192455___________ +1.36 +1.230.0080.0080.0501274817348157376.373__
192549___________ +1.19 +1.180.0050.0080.0181297415463153526.1006_
193959___________ +1.35 +1.420.0540.0880.0763952853317562846.1554_
193411___________ +1.19 +1.120.0120.0110.0791254814943140296.2100_involvedinbudsiteselection
*194156___________ +1.53 +1.470.0020.0050.0081287219726188936.2620_hypotheticalprotein
*191160___________ -1.26 -1.390.0020.0080.0042920623250210236.3135_conservedhypotheticalprotein
192440___________ +1.28 +1.140.0110.0090.0941365017523155146.3618_
192587___________ +1.24 +1.260.0050.0090.0171329716509168016.4110_
*1970_____________ +1.66 +1.570.0010.0030.0081506925045236836.4580_hypotheticalprotein
195606___________ +1.13 +1.050.0670.0610.1521261814206133096.5066_hypotheticalprotein
*192308___________ +5.06 +4.770.0000.0000.000236631198281127786.5542_6-phosphofructose-2-kinase
19731____________ -1.02 -1.020.8040.9800.5531523814877149756.6012_involvedinglycoproteinexportfromtheendoplasmicreticulum
193666___________ +1.18 +1.130.0110.0100.0781317115581148266.6477_conservedhypotheticalprotein
*193115___________ +1.15 +1.190.0400.2100.0302417227900287056.6930_hypotheticalprotein
*194829___________ +1.23 +1.320.0020.0120.0023604844218476786.7382_requiredfornormalintracellularubiquitinmetabolismandfornormalratesofproteolysisofubiquitin-dependentproteolyticsubstratesinvivo
*196438___________ +1.30 +1.300.0020.0080.0052259629377294416.7816_serinepalmitoyltransferasecomponentthatcatalysesthecommittedstepinsphingolipidsynthesis,thecondensationofserinewithpalmitoyl-CoAtoform3-ketosphinganine
*193268___________ -2.31 -2.030.0000.0000.0004510881952652226036.8268_translationallycontrolledtumorprotein
195464___________ -1.07 +1.160.4520.8490.2506800563816789786.8700_hypotheticalprotein
*195890___________ +1.29 +1.220.0160.0160.0711270916389154596.9149_
19868____________ -1.19 -1.180.0270.1140.0261202610077101686.72___
191072___________ +1.10 +1.080.0350.0300.1291267713974136736.709__hypotheticalprotein
*191508___________ +1.42 +1.310.0040.0060.0151562422166205286.1306_hypotheticalprotein
*191531___________ +1.31 +1.250.0060.0110.0231897724886236986.1855_
*192021___________ +3.13 +2.690.0000.0010.0012395675065644446.2377_
*19171____________ +1.60 +1.400.0010.0020.0033726759620520936.2906_
195047___________ +1.17 +1.130.0070.0120.0271523917899172406.3389_hypotheticalprotein
*191333___________ +1.52 +1.280.0020.0030.0143540353748453836.3886_drugtransporter
*195506___________ +2.19 +2.500.0010.0020.0021660636355414916.4354_phospholipaseC
*195780___________ +1.31 +1.340.0010.0040.0052565033556343386.4853_
*196160___________ +1.39 +1.270.0040.0040.0541185031647771505266.5318_
196359___________ +1.00 +1.030.4040.2600.5381326013310137206.5788_peptidaseoftheproteinsortingmachinery
*196090___________ +1.95 +2.420.0010.0030.0012261344094547876.6254_
*19829____________ +1.61 +1.780.0030.0080.0101584325461282096.6721_
*196905___________ +1.27 +1.140.0030.0030.0452387830411272376.7169_conservedhypotheticalprotein
*196075___________ -1.32 -1.640.0000.0020.0007734358404472596.7619_transcriptionalregulatorinvolvedincellcycleregulation
*197164___________ -1.22 -1.490.0000.0030.0003205026366215406.8064_serine/threonineproteinkinase
*197053___________ +5.36 +4.450.0000.0000.000265481424201181576.8500_regulatorysubunitforphosphoproteinphosphatasetype1(PP-1)
*197590___________ -1.46 -1.690.0040.0200.0068084255422478276.8939_NADHdehydrogenase(ubiquinone)78Kchainprecursor,5-primeend
*1997_____________ +3.53 +4.630.0000.0010.0001494852738692706.388__
191618___________ +1.50 +1.260.0070.0100.0321217018208153146.1027_
*196253___________ -1.28 -1.360.0000.0030.0007420557854544856.1569_
195741___________ +1.25 +1.170.0050.0070.0321282816090150566.2111_
*19713____________ +1.32 +1.260.0020.0040.0082464032607311216.2634_
194715___________ +1.39 +1.140.0070.0060.0761448620120164456.3150_
19755____________ -1.05 -1.100.1520.3230.1081921418248174556.3634_mitochondrialribosomalproteinL37
*195555___________ +2.11 +2.020.0010.0020.0021462830817296166.4124_
*194758___________ -1.76 -2.100.0010.0040.00215234186486726586.4597_mitochondrialcomplexINUIMTYKYsubunit(protontranslocation)|NADH:UbiquinoneOxidoreductase(ComplexI)
*191234___________ +3.60 +3.510.0000.0010.0011828465756641576.5083_hypotheticalprotein
*192677___________ +1.62 +1.510.0000.0000.0012598642189392136.5557_GPItransamidasecomponent
196266___________ +1.17 +1.190.0090.0140.0291627618975193826.6025_hypotheticalprotein
193679___________ -1.14 -1.170.0680.1220.0797054662067605016.6490_conservedhypotheticalprotein
*193100___________ +1.52 +1.620.0040.0080.0111305019856211696.6944_
*193984___________ +1.54 +1.470.0050.0110.01566496102614977146.7397_
*196423___________ +1.11 +1.130.0280.0260.1033211035501363856.7831_fructose-2,6-biphosphatase
*193282___________ +1.73 +2.170.0030.0120.0071245221573270626.8282_hypoheticalprotein
197464___________ +1.31 +1.200.0040.0050.0381386318193166436.8716_conservedhypotheticalprotein
*195873___________ +1.63 +1.420.0020.0040.0151997532487283326.9164_DNA-directedDNApolymerasealpha
193549___________ +1.27 +1.210.0050.0100.0151378817470166316.102__
195612___________ +1.32 +1.190.0040.0060.0161265016739150866.728__
192228___________ +1.27 +1.190.0030.0050.0191490518924176846.1321_twinfilinA|actinmonomersequesteringprotein
*193809___________ +1.23 +1.170.0250.0200.1322141426334251266.1870_
*192242___________ +2.90 +2.690.0000.0000.0003041988171816876.2390_
1945_____________ +1.25 +1.250.0050.0110.0131308816321163496.2924_agglutinin-likeprotein9
*195124___________ +1.28 +1.300.0010.0040.0022188327969285556.3407_hyphallyregulatedprotein
*19415____________ -1.51 -1.480.0010.0040.0033632223976244806.3900_homologofS.cerevisiaeYGR235C
*193507___________ -3.52 -3.600.0000.0000.00023655467267657986.4367_cytochromeb5reductase
192995___________ +1.21 +1.080.0200.0160.1201409017080152286.4870_lowtemperatureresponsiveprotein
*191589___________ +1.39 +1.310.0040.0060.0151688623400220546.5331_componentofRNApolymeraseIcoretranscriptionfactor
19994____________ +1.03 +1.010.6960.4560.7831500415398151046.5803_
*19396____________ +1.23 +1.220.0100.0110.0571527618769186546.6268_hypotheticalprotein
19520____________ +1.25 +1.290.0050.0120.0141484118486191326.6733_
*196918___________ +1.20 +1.340.0040.0180.0071868422379249896.7182_hypotheticalprotein
196528___________ +1.06 +1.020.3680.2300.5311977521025201686.7632_hypotheticalprotein
*197179___________ -1.23 -1.260.0080.0190.0192946124036234486.8079_heatshockprotein
197353___________ +1.07 +1.040.0760.0500.2531241113339129156.8512_
*197603___________ -1.41 -1.450.0010.0020.0014151029411286006.8951_conservedhypotheticalprotein
19714____________ -1.08 -1.070.1180.1610.1301161710795108206.408__GTPbindingproteininvolvedinvesiclefusioninthesecretorypathway

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
19850____________ +1.44 +1.260.0030.0050.0161226217689154786.1044_amidasespecificforN-terminalasparagineandglutamine
193067___________ +1.12 +1.130.1730.3750.1161416615859160506.1588_partofhistonedeacetylasecomplex
191050___________ +1.28 +1.180.0060.0070.0391249615974147976.2132_
192624___________ +1.26 +1.190.0050.0060.0301256815823149446.2650_hypotheticalprotein
*194318___________ +2.25 +2.110.0010.0020.0051484433387313106.3171_
194189___________ +1.27 +1.130.0060.0060.0491257015962141606.3646_weaksimilaritytoacidphosphatase
*195376___________ +1.19 +1.210.0100.0210.0241649819679199146.4138_proteinkinase
*194308___________ +2.12 +2.170.0010.0040.0051652235050359016.4613_negativeregulatorofswe1kinase
196116___________ -1.08 -1.100.8060.7930.5978538379354777546.5097_aldohexosespecificglucokinase
192336___________ +1.20 +1.140.0040.0090.0151396516766158556.5572_similartotheplantPR-1classofpathogenrelatedproteins
196277___________ +1.02 +1.040.3890.3500.3561247412690129576.6038_
19434____________ +1.08 +1.050.0930.0570.3111289613873135376.6504_
195175___________ +1.23 +1.180.0700.0680.1441342916463158416.6960_
193998___________ +1.22 +1.160.0060.0060.0601381216840160756.7411_hypotheticalprotein
*196406___________ -2.06 -2.380.0000.0010.0015691027586239476.7848_putativemitochondrialribosomalprotein
*195307___________ -32.72 -34.770.0000.0000.00046382114177133386.8296_
197480___________ +1.08 +1.040.1070.0550.4481543916694161196.8732_hypotheticalprotein
19163____________ +1.26 +1.260.0040.0080.0161437218085181246.156__pantoate-beta-alanineligase,pantothenicacidbiosynthesis
6748_____________ +1.07 +1.120.0280.0440.0571264213588141276.748__
191340___________ +1.22 +1.170.0060.0070.0311322416082154916.1342_aldosereductase
*191574___________ +1.36 +1.340.0040.0080.0112181229651292736.1886_TFIIDsubunit|componentoftheTAF(II)complex
194571___________ +1.23 +1.070.0140.0100.1791274815712136016.2404_
*191206___________ +3.35 +3.300.0000.0010.0012277976279751956.2939_irontransportmulticopperoxidase
192186___________ +1.22 +1.130.0120.0120.0651552418982176116.3422_nuclearporeprotein
192508___________ +1.16 +1.080.0200.0150.1481295615023139956.3913_hypotheticalprotein
192870___________ +1.20 +1.060.0760.0320.7521735420830184496.4379_
*191323___________ +1.31 +1.240.0100.0130.0362172828460269356.4885_clathrinassemblycomplexbetaadaptincomponent
191577___________ +1.01 +1.060.1070.1520.1201367613867145316.5343_
*196367___________ -1.64 -1.870.0000.0010.0004999230484267156.5819_heatshockproteinoftheHSP70family
195093___________ +1.03 +1.010.3770.1970.7421974720258199896.6283_chromatinmodeling
*19535____________ -3.13 -2.870.0000.0010.0005453917433190166.6746_
*193300___________ +1.64 +1.510.0010.0040.0052868047030433206.7195_nucleolarzinc-fingerprotein
*196514___________ +2.59 +2.390.0000.0000.0002868074402686246.7646_copperhomeostasis,peptideimportregulation
197192___________ +1.03 +1.050.1100.0840.2391266013094133146.8092_hypotheticalprotein
197365___________ +1.05 +1.050.0830.0800.1561273013356133066.8525_FunctionrequiredforYeastViabilityontoxinexposure
197615___________ +1.01 -1.030.4550.3380.4751625616403157536.8964_
191596___________ +1.33 +1.210.0030.0070.0131299517287157106.426__
*191441___________ +1.35 +1.360.0020.0060.0071990226956271346.1060_hypotheticalprotein
191161___________ +1.31 +1.230.0060.0080.0261322817372162746.1610_phospholipaseD
*191078___________ +1.32 +1.110.0050.0040.1092705535599299826.2148_
191776___________ +1.26 +1.130.0060.0070.0491289216236145676.2664_pantotheine-phosphateadenylyltransferase
194721___________ +1.25 +1.130.0080.0090.0501285016068145736.3183_hypotheticalprotein
19763____________ -1.02 -1.070.3520.9490.1812598725389243746.3663_smallsubunitofthenuclearmRNAcap-bindingproteincomplexCBC
191686___________ +1.27 +1.130.0080.0080.0721572819914178216.4153_conservedhypotheticalprotein
*195710___________ +1.61 +1.560.0020.0040.0091530824704239446.4637_
*196243___________ +1.39 +1.280.0020.0040.0111816525310232936.5115_
192320___________ +1.21 +1.090.0100.0100.0701280215482138996.5586_
194940___________ +1.09 +1.030.0960.0500.4331225213379126746.6050_histidinepermease
196623___________ +1.13 +1.070.0350.0260.1591965822211209896.6520_conservedhypotheticalprotein
*195163___________ +1.24 +1.200.0200.0280.0553883848017464546.6973_mitotictransitionofG2/Mcycle
194011___________ +1.10 +1.100.0190.0200.0711234513615136256.7424_conservedhypotheticalprotein
*196387___________ +1.25 +1.290.0030.0090.0072338629143301666.7866_
195321___________ +1.24 +1.200.0040.0090.0131569619497188726.8310_methylenetetrahydrofolatereductase
*197492___________ +1.18 +1.200.0050.0170.0091698820067203256.8744_conservedhypotheticalprotein
195599___________ +1.17 +1.060.0480.0280.2961237214445131736.170__
191995___________ +1.29 +1.240.0020.0040.0061305216772161486.767__
195568___________ +1.39 +1.260.0010.0030.0081378619132173076.1357_
19854____________ +1.23 +1.080.0060.0070.0392097525801227136.1903_4-aminobutyrateaminotransferase(GABAtransaminase)
194367___________ +1.29 +1.190.3550.9700.1821605820757191476.2422_coiled-coliproteinoftheSMCfamily
194491___________ +1.23 +1.170.0040.0080.0111581219495185236.2952_farnesyldiphosphatesynthetase(FPPsynthetase)|farnesyl-pyrophosphatesynthetase
*191172___________ +2.20 +2.150.0010.0030.0051480832636317666.3437_inorganicphosphatepermease
*196021___________ +1.88 +1.920.0000.0000.0003445164842659766.3925_InducedinHyphalDevelopment
193202___________ +1.33 +1.260.0030.0060.0101712722791216366.4397_membraneproteinsimilartomalarialantigen
194789___________ +1.26 +1.180.0050.0090.0191293716267152356.4899_classIIaldolase
191405___________ +1.21 +1.210.0080.0140.0241309015885157986.5358_p-nitrophenylphosphatase|4-nitrophenylphosphatase
196382___________ +1.07 +1.080.0680.0780.1181251213414135416.5833_
195076___________ -1.33 -1.070.0740.0420.347112326844101052666.6300_profilin
*19549____________ -2.76 -2.990.0000.0000.0007160225987239236.6761_mitochondrialribosomallargesubunitprotein
193312___________ +1.01 -1.020.7240.4760.8201677616977164776.7208_
*195282___________ +2.27 +1.870.0000.0000.0012787263188522586.7660_hypotheticalprotein
197204___________ +1.09 +1.060.0380.0400.0981286814062136446.8104_similarto2-nitropropanedioxygenases
197377___________ +1.08 +1.050.0620.0590.1421225413224128536.8537_anaphasespindleelongationprotein|microtubulebinding
*197629___________ +1.40 +1.630.0030.0090.0061608522588262026.8978_
19633____________ -1.09 -1.070.0520.0960.0671159210652108286.444__putativemethyltransferase
*191594___________ +1.65 +1.490.0020.0030.0191554425622232296.1072_hypotheticalprotein
192670___________ +1.23 +1.180.0040.0060.0181291115869152056.1626_
191274___________ +1.08 +1.070.0840.0620.2241650617867177196.2166_
191244___________ +1.30 +1.190.0120.0150.0481249616195148326.2680_GTPaseactivatingprotein(GAP)forYpt6andMac1interctingprotein
*193214___________ +3.04 +3.360.0000.0010.0011629649484547586.3196_hypotheticalprotein
*195221___________ +1.38 +1.290.0020.0050.0081711823636221626.3682_hypotheticalprotein
*191378___________ +4.96 +5.430.0000.0000.000512762543032786556.4166_
*193547___________ +1.67 +1.760.0010.0040.0022708945347477216.4654_memberofthePUFproteinfamily
196227___________ +1.16 +1.120.0250.0270.0841530017720170826.5130_
191938___________ +1.02 +1.040.4030.3550.3712058720952214476.5601_putativesplicingfactor
194169___________ +1.05 +1.080.1110.1180.1611282713482139096.6063_
*196637___________ +1.18 +1.110.0300.0250.1274405151783488046.6534_predictedglycosilase
*196837___________ -16.65 -16.930.0000.0000.00030556818350180446.6986_benzilreductase
194024___________ -1.00 -1.110.4440.6030.2834774247534431206.7437_riboflavinsynthase
194583___________ -1.11 -1.120.0090.0190.0231847716697164656.7882_mitochondrialcarrierprotein
*195335___________ +1.52 +1.510.0020.0040.0071629424760246306.8325_
68757____________ +1.09 +1.050.0840.0440.4181323714480138926.8757_
192847___________ +1.20 +1.160.0080.0090.0391256815058146396.186__
191622___________ +1.14 +1.090.0420.0370.1341275014530138726.788__
192296___________ +1.22 +1.300.0040.0250.0061506518425196396.1373_hypotheticalprotein
192445___________ +1.25 +1.100.0080.0080.0641291216181142556.1918_
*195229___________ +1.55 +1.480.0050.0110.0171369421275203046.2439_3'-5exoribonucleaserequiredfor3endformationof5.8SrRNA
194411___________ +1.14 +1.130.0320.0320.1041303414854147526.2971_histonedeacetylase
195207___________ +1.10 +1.080.0260.0340.0641327414595143256.3451_
*195294___________ +2.56 +2.470.0000.0000.0003601992192889136.3940_betasubunitofpyruvatedehydrogenase
*194045___________ +1.63 +1.550.0020.0040.0072332037939362186.4413_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*195732___________ +2.31 +2.590.0000.0020.0011913944200494986.4911_nuclear/nucleolarGTP-bindingprotein2
*192138___________ +2.79 +3.210.0000.0010.0012168360483697066.5373_
*193884___________ +1.44 +1.790.0040.0130.0101538222160275286.5853_
194390___________ +1.02 +1.020.8620.6550.8266043061471613436.6317_hypotheticalprotein
*196667___________ +1.43 +1.290.0020.0030.0091983028421255096.6776_subunitofthehistonedeacetylaseBcomplex
19337____________ +1.15 +1.140.0170.0150.0941635718853186736.7221_v-SNAREinvolvedinseveralproteintransportsteps
195269___________ +1.18 +1.160.0040.0060.0151849021851214256.7673_conservedhypotheticalprotein
*197216___________ +1.49 +1.330.0000.0000.0024387165308584046.8116_GTP-bindingproteinoftherab/yptfamily
197389___________ +1.32 +1.280.0020.0060.0061556620579198986.8549_DNApolymerasezeta
*197645___________ +3.47 +3.040.0000.0010.0012257478420685226.8993_biotinholocarboxylasesynthetase
19317____________ +1.12 +1.070.0380.0230.2622053122922219776.462__
*191607___________ +2.81 +2.810.0000.0010.0011904453595535006.1088_
*191672___________ +1.53 +1.360.0010.0020.0051730626462235796.1640_coatomercomplexalphachainofsecretorypathwayvesicles
*194733___________ +1.15 +1.160.0080.0200.0172374227220275296.2186_
*192724___________ +1.72 +1.510.0010.0030.0051547226652233506.2695_hypotheticalprotein
19469____________ +1.24 +1.140.0070.0150.0201814022432206586.3212_MAPkinasekinase(MEK)ofthepheromonepathway
1987_____________ +1.39 +1.300.0010.0040.0041677223302217276.3698_
*195487___________ +1.59 +1.450.0010.0030.0062112133536306016.4181_partofARSreplicationinitiationcomplex
*192568___________ +1.39 +1.350.0010.0030.0031159561606221565666.4670_
193903___________ +1.22 +1.080.0090.0060.1971242815199134156.5145_hypotheticalprotein
*191853___________ +4.70 +3.920.0000.0000.000305161433431196826.5620_histoneH3
194183___________ +1.03 -1.020.5000.2710.8622147422125210076.6077_Pro/Ser-richprotein
196650___________ +1.22 +1.150.0070.0090.0391595219537183276.6547_hypotheticalmembraneprotein
*196850___________ +1.33 +1.250.0010.0020.0044315457486538756.6999_conservedhypotheticalprotein
*194040___________ -1.85 -1.750.0000.0000.00010274255414587406.7451_
*194597___________ +1.27 +1.250.0000.0010.0023969850436495116.7896_F-actincappingproteinbetasubunit
195351___________ -1.04 -1.050.7880.5310.8937490372037715066.8340_translationinitiationfactoreIF1A
*197519___________ +1.33 +1.040.0110.0060.7986706289438694226.8771_hypotheticalprotein
*195623___________ +4.01 +4.080.0000.0000.000268231076111093576.203__
*1990_____________ +1.62 +1.630.0020.0050.0051536024930250856.812__
*192427___________ +1.76 +1.730.0020.0050.0051623328576281006.1391_
19552____________ +1.23 +1.090.0140.0130.0941551719039169156.1931_involvedinbreakdownofautophagicvesiclesinthevacuole
*191605___________ +1.61 +1.630.0000.0010.0011559125084253886.2454_DNAmismatchrepairprotein
*191110___________ +1.40 +1.320.0010.0030.0041718224128226356.2986_thiaminpyrophosphokinase
191113___________ +1.21 +1.180.0070.0140.0201724420912204156.3465_hypotheticalprotein
*193763___________ +1.39 +1.320.0010.0020.0021956627276258836.3956_conservedhypotheticalprotein
*195589___________ +2.46 +2.710.0000.0000.0003612488992979666.4431_hypotheticalprotein
*191064___________ -18.63 -15.730.0000.0000.00082131144090522076.4925_acetyl-coenzymeAsynthetase
*192156___________ -1.93 -2.130.0000.0010.00210127552509476106.5390_
*193131___________ -1.04 +1.150.0400.2700.0275873656346673956.5868_NADPHdehydrogenase
*195119___________ -1.54 -2.050.0030.0180.00511603467525465647606.6330_
196682___________ -1.20 -1.120.1140.0610.4297039758689627666.6791_
*19350____________ +1.21 +1.300.0010.0130.0024720157073615366.7234_20SproteasomecomponentY13
*195257___________ -2.99 -2.760.0000.0000.00011005836815398516.7685_sphingolipidlongchainbasekinase
*197231___________ +1.41 +1.460.0020.0050.0091523221478221736.8131_plasmamembraneironpermease
*197402___________ +1.86 +1.780.0000.0000.0003520265550625866.8562_potentiallyinvolvedinmeiosisandtranscriptionalsilencing
197662___________ -1.18 -1.240.0570.0870.0823874532873312796.9010_regulatorofTy1Transposition
*194225___________ +2.03 +2.070.0020.0080.0061617332785334936.483__
*194776___________ +1.31 +1.370.0000.0010.0012530333058346196.1105_zincfingertranscriptionfactoroftheLYS14family
193147___________ +1.25 +1.150.0050.0060.0321288716096148816.1657_conservedhypotheticalprotein
*196247___________ +1.29 +1.420.0000.0030.0012077326901294016.2199_DNApolymerasealphabindingprotein
19646____________ +1.03 -1.110.5660.8790.3342166682241981960196.2713_
193938___________ -1.27 -1.290.0670.0460.2342749621621213476.3225_
*196479___________ +1.26 +1.310.0010.0080.0023085738893403466.3715_SNAREbinding,latestageofsecretion
*194504___________ -2.17 -2.150.0010.0020.0024602221228214346.4196_alcoholdehydrogenase
192583___________ +1.26 +1.100.0220.0190.1041465118468161206.4684_peptidetransporter
*19213____________ +1.33 +1.450.0010.0040.0014055653863587666.5160_26Sproteasomeregulatorysubunit
*19323____________ +1.72 +1.810.0000.0010.0002295739489414386.5634_
*192173___________ +1.57 +1.680.0000.0010.0012903945519488166.6090_nuclear-cytoplasmictransport|negativeeffectorofPolIIIsynthesis
19670____________ +1.16 +1.220.0510.1650.0451755622028832139676.6563_sumoylationfactorassociatedwithkinetochorfunction
*196862___________ +1.32 +1.500.0010.0080.0012513733226377426.7011_conservedhypotheticalprotein
*192091___________ -3.32 -3.310.0000.0000.00022865468907691736.7464_subunitNUHMofNADH:UbiquinoneOxidoreductase
*194611___________ +1.57 +1.700.0000.0000.0004030063237685716.7910_ribose-phosphatepyrophosphokinase
195367___________ +1.30 +1.290.0070.0110.0231356617638175226.8356_helicaserequiredformitoticdiploid-specificrecombinationandrepair
197537___________ +1.13 +1.080.0410.0410.1131427116189154636.8788_
*192782___________ -1.46 -1.700.0060.0160.0126351843484373436.14___
199______________ +1.16 +1.130.0070.0130.0191305415171147626.507__hypotheticalprotein
19230____________ +1.02 +1.030.6890.4840.6961242112726128026.1122_hypotheticalprotein
191772___________ +1.12 +1.240.0120.0850.0131368215307169646.1678_conservedhypotheticalprotein
*196470___________ +2.36 +1.840.0070.0150.0193606085049664566.2214_alkylhydroperoxidereductase
192713___________ -1.05 -1.030.3020.1770.5281170811186114206.2730_
191725___________ +1.09 +1.040.2130.1240.4611212113196126436.3239_
193088___________ +1.09 +1.130.0350.1910.0281267313853143606.3733_hypotheticalprotein
193754___________ +1.23 +1.290.0030.0110.0071380617024178136.4212_secretedacidphosphatase
192740___________ +1.00 +1.100.1030.7220.0501223912255135206.4697_
192417___________ +1.07 +1.150.0100.0790.0111246113336142796.5177_
*193973___________ +1.02 -1.480.0180.3650.0123320633852224706.5649_conservedhypotheticalprotein
193417___________ +1.03 +1.020.4260.5250.2921673017288171086.6109_
192771___________ +1.18 +1.100.1380.1190.2222095724637231246.6581_rhoGTPaseactivatingprotein(GAP)
*191896___________ -1.69 -1.970.0050.0140.0123079418224156356.7025_
192076___________ -1.11 -1.110.0630.0990.0841884717038169076.7479_conservedhypotheticalprotein
194625___________ +1.13 +1.180.0040.0260.0051329314970157386.7924_transcriptionfactorIIA,smallchain
*197288___________ -2.75 -3.050.0000.0010.0004701017109154006.8370_
*196828___________ +1.48 +1.510.0060.0150.0151417221004213376.8803_proteinInvolvedinprocessingrRNAprecursorspeciestomaturerRNAs
Cachs1___________ -1.01 -1.040.6980.9180.445118641171611361Cachs1_
191009___________ +1.22 +1.200.0070.0140.0211544018783185366.219__
191935___________ +1.21 +1.160.0020.0060.0091309015860151936.831__hypotheticalprotein
191976___________ -1.00 -1.090.6250.4450.6263150631363288236.1408_thioredoxinII
193517___________ -1.08 -1.070.1120.0900.2252249520764209396.1950_conservedhypotheticalprotein
*192157___________ -1.71 -1.570.0010.0020.0086835039858435926.2471_
*191096___________ +1.54 +1.770.0010.0060.0011583424345280616.3001_chloridechannel,possiblyvoltagegated
*19132____________ +1.38 +1.610.0030.0160.0061397819241224686.3482_
*194250___________ -1.45 -1.820.0010.0070.0013066421140168806.3974_hypotheticalprotein
*19309____________ +1.77 +1.730.0000.0020.0013390459923585926.4447_allantoatepermease
192849___________ +1.81 +1.320.0700.0580.1805143949303306788036.4943_aquaporin
*196186___________ -1.47 -1.550.0020.0050.0044168228429269246.5407_hypotheticalprotein
*192262___________ -1.75 -2.150.0030.0080.0088912250935414846.5884_NADPH:quinonereductase|zeta-crystallin
*195103___________ +1.53 +1.690.0010.0040.0011579724101267656.6347_phosphoglyceratemutase
196698___________ +1.04 +1.090.1950.2760.1651381814379150976.6806_
*194438___________ +2.93 +3.280.0000.0000.00030852904971012566.7251_zinc-fingertranscriptionfactor

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
195244___________ +1.02 +1.020.4970.2630.9812871329213293576.7698_morphogenesischeckpointdependent
197245___________ +1.00 -1.040.6080.4780.5471583015867152576.8145_conservedhypotheticalprotein
197417___________ -1.16 +1.020.0940.0390.9388250827095168421036.8577_thiol-specificantioxidantprotein
*197676___________ -2.63 -3.300.0000.0020.0014868218510147746.9024_sorbitoldehydrogenase
*192457___________ +1.34 +1.190.0130.0110.0921891925393225306.34___
19736____________ +1.21 +1.120.0040.0050.0271283915584143416.526__subunitofactivationmediatorsubcomplexofRNApolymeraseIIholoenzyme
191373___________ +1.48 +1.380.0020.0040.0071398220729192486.1145_
194330___________ +1.20 +1.100.0090.0110.0401301815659143406.1696_
*193599___________ +1.52 +1.330.0040.0080.0181421221579188696.2230_
193635___________ +1.25 +1.200.0050.0090.0161556819464186686.2751_
*194330___________ +1.34 +1.360.0030.0070.0081756823469238666.3255_
*19846____________ +1.79 +1.810.0020.0040.0082710248560491216.3748_putativeserine/threonineproteinkinase
*194894___________ -2.10 -1.900.0010.0020.0023827118207201396.4230_similartodemethylmenaquinonemethyltransferase
194659___________ +1.32 +1.230.0040.0090.0111630321600200256.4710_pre-mRNAsplicingfactor
*194295___________ +1.42 +1.530.0040.0110.0101382919657211626.5190_
196152___________ -1.06 +1.090.3170.8320.1642466023312269816.5662_conservedhypotheticalprotein
192901___________ +1.19 +1.220.0140.0250.0341253514965153046.6120_
192760___________ +1.23 +1.220.0040.0120.0101675420620204576.6593_
*191881___________ +1.66 +1.910.0000.0000.0003117051657595986.7039_conservedhypotheticalmembraneprotein
192064___________ +1.11 +1.040.0810.0370.5701336414865139576.7491_conservedhypotheticalprotein
*197012___________ -1.68 -1.690.0010.0030.0033017417951178056.7938_mitochondrialribosomalproteinS24
197301___________ +1.09 +1.020.2820.1690.4921276013901129746.8383_
*196812___________ +2.33 +2.450.0010.0030.0031343431236329736.8819_dolichyl-P-mannose-proteinmannosyltransferase
Cafks2___________ +1.02 +1.030.3830.2480.515120211228812379Cafks2_
193336___________ +1.24 +1.040.0080.0050.3911203014900125446.239__hypotheticalprotein
191210___________ +1.10 +1.170.1850.3560.1292953832447344906.843__vacuolaraminoacidtransporter
*19454____________ +1.79 +2.020.0000.0010.0002818250542568336.1425_
191911___________ +1.05 +1.160.0840.4940.0463439135980398906.1967_
194068___________ +1.35 +1.240.0060.0070.0311317417839163936.2486_hypotheticalprotein
*194059___________ +2.08 +1.870.0020.0040.0061384628749258256.3015_
195184___________ -1.23 -1.070.1540.0810.4888508968980798856.3495_
194349___________ +1.22 +1.230.0080.0140.0231265015378155286.3994_
*195521___________ -1.23 -1.290.0170.0440.0266204450434482556.4463_IronSulfurAssembly
192476___________ +1.22 +1.210.0090.0190.0231574519134189776.4958_
*196202___________ +3.18 +3.510.0000.0000.0002305073336808246.5422_pathogenesisrelatedprotein,repressedbyTUP1protein4
192247___________ +1.05 +1.170.0980.1400.1151246813079146446.5899_conservedhypotheticalmembraneprotein
*191999___________ +3.49 +3.330.0000.0000.0002174875963723246.6361_hypotheticalprotein
194115___________ +1.03 +1.050.2640.1990.3491309013432137276.6821_hypotheticalprotein
194450___________ -1.01 -1.080.4570.8990.2501724817082160386.7263_zincfingertranscriptionfactor
*196966___________ +1.66 +1.590.0000.0010.0012243637316357866.7712_cholinekinase
197260___________ -1.13 +1.000.1250.0540.7863915234779392166.8160_similaritytoaldosereductases
*197433___________ +2.21 +2.920.0000.0010.0012475054719721746.8591_
195999___________ +1.19 +1.140.0300.0240.1371232214646140246.9039_
*194890___________ +1.58 +1.570.0040.0120.0071712326998268736.54___
19261____________ +1.08 +1.100.0230.0510.0371291413911142676.549__
193172___________ +1.00 +1.000.8630.8390.6611416214163141696.1163_
194697___________ -1.00 +1.020.6290.9550.3811248812481127326.1712_
191393___________ +1.04 +1.050.4430.4980.3201611216795169896.2245_mitochondrialcarrierprotein
194221___________ +1.02 -1.030.9290.9590.7391394814161134946.2766_orginrecognitioncomplexsubunit
192857___________ +1.07 +1.150.4430.2290.8791364814644156346.3275_
193460___________ +1.24 +1.410.0030.0100.0051366416994192786.3763_
*191281___________ +1.46 +1.450.0040.0140.0081592023290230466.4244_conservedhypotheticalprotein
*19577____________ +1.31 +1.290.0090.0230.0191993226173257406.4727_conservedhypotheticalprotein
*194282___________ +2.43 +2.810.0010.0030.0011561637974438796.5204_hypotheticalprotein
196137___________ -1.08 -1.140.0790.0720.1622207320383194276.5677_hypotheticalprotein
192888___________ +1.05 +1.170.0240.4940.0141372814430160416.6134_hypotheticalprotein
194239___________ +1.00 -1.010.3950.1960.9191202512037119326.6607_
*191868___________ +2.04 +2.070.0000.0040.0012144543794443266.7052_smallsubunitofribonucleotidereductase
193811___________ -1.05 -1.010.3050.2480.3451675016003166466.7506_GTPaseactivatingprotein
*197025___________ +1.70 +1.920.0020.0070.0031793330492344406.7951_transcriptionfactoroftheMADSboxfamily
*197316___________ -1.25 -1.280.0100.0180.0263174225412247556.8397_conservedhypotheticalprotein
*196800___________ +1.35 +1.640.0050.0230.0091476219947242086.8831_proteininvolvedinoxidativestress
Casmi1___________ -1.06 -1.070.1820.4070.117122601157611509Casmi1_
*19661____________ +2.62 +2.760.0000.0000.0001803147257497416.254__
*6862_____________ -1.35 -1.280.0090.0120.0364447433035347206.862__
19118____________ -1.09 +1.140.1470.0800.4544075237224465606.1443_oleatedelta-12desaturase
19692____________ +1.00 +1.080.8150.9680.5683171031786343396.1983_possibleperoxin
1999_____________ +1.20 +1.120.0170.0340.0331330015946149026.2501_
*193647___________ +1.21 +1.600.0090.0450.0121329816121212316.3030_componentofexocystcomplex
193963___________ -1.07 +1.010.3290.1670.7342701825323271646.3508_conservedhypotheticalprotein
192942___________ +1.18 +1.140.0090.0200.0221254814751143536.4007_
193180___________ -1.01 +1.000.7920.5510.8375511254613552766.4477_inositolpolyphosphate5-phosphatase
*192463___________ +1.28 +1.220.0170.0420.0292222028473270956.4972_RNApolIItranscriptioncofactor
196284___________ -1.12 -1.070.2170.1720.3044127936947386786.5434_signalrecognitionparticlebetasubunit
*194932___________ -5.59 -5.930.0000.0000.00020722637080349716.5912_mitochondrialtranslationelongationfactor
*191413___________ -2.06 -2.300.0010.0020.0027406835996322256.6382_regulatorofmitochondrialironaccumulation
194100___________ +1.21 +1.130.0120.0270.0251352916415153116.6838_
*19900____________ +1.62 +2.020.0030.0180.0051994132243403456.7276_
*196979___________ +2.00 +2.580.0000.0040.0011732534587446276.7725_hemolysin-likeproteinrequiredfornormalmitochondrialstructure
*197274___________ +1.61 +2.060.0020.0080.0041542124822317936.8174_
*197445___________ +3.78 +5.580.0000.0010.00018148686001013286.8605_peripheralvesiclemembraneprotein
195984___________ -1.01 -1.020.8050.6400.7081575715611154946.9053_conservedhypotheticalprotein
*19150____________ +1.48 +1.400.0000.0010.0032693239928376786.75___mitochondrialinnermembraneimporttranslocasesubunit
19916____________ +1.18 +1.180.0020.0050.0081651019442194576.569__conservedhypotheticalmembraneprotein
19115____________ +1.23 +1.120.0020.0030.0211250115422140596.1183_hypotheticalprotein
*19708____________ +1.57 +1.440.0010.0020.0041503923668216686.1728_spindlepolebodycomponent
*193757___________ -1.28 -1.630.0310.0500.0586369649936389746.2263_proteinassociatedwithmitochondrialATPsynthase
191144___________ +1.31 +1.170.0090.0100.0451268016656148206.2786_
*193618___________ +2.98 +4.200.0000.0000.00030104897851263806.3289_
*194361___________ +1.29 +1.250.0050.0080.0192082726869260476.3777_
*192211___________ -6.95 -5.170.0000.0000.00021289083062234115376.4256_hypotheticalprotein
*192117___________ -2.26 -2.090.0000.0010.0016368228169304826.4744_mitochondrialcarrierprotein
*194813___________ +1.58 +1.740.0000.0010.0004494671235780466.5219_GMPsynthase
19586____________ -1.02 -1.000.7470.8190.5141755017286175346.5694_ER-Golgitransportvesicleprotein,componentofcopII
195831___________ +1.04 +1.010.3990.2210.6831236912869124616.6147_hypotheticalprotein
*195788___________ -2.18 -2.000.0000.0000.0015952842730772978376.6622_
*19501____________ +1.81 +2.340.0010.0040.0011631429583382016.7069_
193826___________ +1.23 +1.210.0080.0230.0161771421819214556.7521_hypotheticalprotein
197038___________ +1.11 +1.060.0470.0280.2861233413733130676.7964_peripheralGolgiproteinrequiredforvacuolarproteinsorting
*197327___________ +1.38 +1.400.0010.0050.0042016627793281926.8408_inorganicphosphatetransport

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
196787___________ +1.23 +1.160.0060.0110.0231321716215153396.8844_14KDaproteinfoundonER-derivedvesicles
41959____________ +1.03 +1.020.3090.1990.4621212612446124264.1959_
19226____________ +1.32 +1.240.0090.0170.0251243616405154026.274__hypotheticalprotein
191809___________ +1.22 +1.080.8360.7560.6612453630032265416.882__
192638___________ +1.29 +1.200.0070.0080.0391315616917158216.1459_
19246____________ +1.03 +1.190.4160.9010.2222471625518292916.1996_
*192726___________ -1.16 +1.140.0150.0200.0473106226868353476.2518_plasmamembraneproteininvolvedinphosphatidylethanolaminebiosynthesisandotherprocesses
194524___________ +1.02 +1.030.7460.5470.7141514515491156046.3047_zincfingertranscriptionfactor
*19637____________ -1.24 -1.210.0120.0970.0123050124603251766.3524_succinatedehydrogenasesubunit
*194751___________ -1.26 -1.200.0170.0220.0533226025621268286.4021_mitochondrialribosomesmallsubunitcomponent
*192831___________ +1.46 +1.430.0000.0030.0013922857288559026.4492_DNA-directedRNApolymeraseIIIsubunit,HMG-like
*193475___________ +6.03 +5.200.0000.0000.000455062742242366676.4984_
194686___________ +1.18 +1.210.0510.0510.1221279715143154606.5450_conservedproteinwithsimilaritytomitochondrialaldehydedehydrogenase
*197550___________ -1.23 -1.300.0150.0200.0473530612869022718086.5927_
191427___________ +1.30 +1.200.0020.0040.0121694221975203846.6396_conservedhypotheticaltransporter
194086___________ -1.19 -1.190.0050.0100.0142704922690226886.6850_putativetyrosinephosphatase
19886____________ -1.06 -1.170.4220.9920.2246835264296581986.7291_
*196991___________ +1.37 +1.490.0000.0010.0003194243707475806.7737_20Sproteasomesubunit|multicatalyticendopeptidase
*19939____________ +1.73 +1.970.0000.0000.00054486940981076046.8188_helicase
197457___________ +1.25 +1.170.0300.0210.1801588819917186546.8617_hypotheticalprotein
195971___________ +1.02 +1.010.6060.3460.9651205312303121596.9065_
*19922____________ +2.56 +2.060.0000.0010.00147043120497967056.98___
*192026___________ +1.62 +1.580.0040.0060.0162143834668339576.591__
191434___________ +1.08 +1.090.0240.0620.0331269013757138416.1203_
191177___________ +1.02 +1.020.6990.7290.4901346213756136826.1744_
19470____________ +1.18 +1.190.0170.0680.0201521317894181666.2280_
191490___________ -1.01 +1.020.6880.8310.4491246612345127126.2803_
193659___________ +1.15 +1.060.1380.1130.2371664619204176156.3302_conservedhypotheticalprotein
195722___________ +1.05 +1.070.2190.2860.1871355214250144686.3798_
*192614___________ +1.70 +1.560.0010.0030.0041953333130305316.4271_GtTP-bindingproteinoftherassuperfamilyinvolvedinbudsiteselection
192101___________ +1.08 -1.310.2280.5000.1363557438305272326.4760_coiled-coilmembraneprotein
194143___________ -1.01 +1.110.0900.7270.0441458414468162256.5236_
192982___________ -1.01 +1.010.3770.9180.1971247512344125846.5707_involvedinautophagy
192478___________ -1.03 -1.010.6160.4030.6971202011661119166.6160_
195804___________ +1.04 -1.040.9840.9090.9132355324516226886.6638_5-oxoprolinase|hydantoinutilizationproteinA
19487____________ -1.05 -1.040.5080.6250.3341292412319124276.7084_N-acetylglucosaminyl-phosphatidylinositol(GPI)biosyntheticprotein
193841___________ +1.03 +1.030.3440.2600.4001246812895128466.7537_
195031___________ +1.08 +1.140.0630.1020.0831668617947190206.7978_putativereponseregulatortwo-componentphosphorelaygene
197341___________ +1.10 +1.060.1010.0970.1731510516608160826.8422_conservedhypotheticalprotein
196776___________ +1.03 +1.000.7240.4810.8031231412731123266.8855_translationinitiationfactoreIF2B
42408____________ -1.06 -1.060.2700.3370.2171181411182111894.2408_
*196492___________ +3.72 +4.280.0000.0000.0001781166213762386.289__ser/thrproteinkinase
193195___________ +1.12 +1.170.0020.0100.0051319314839154676.908__
*192779___________ +2.01 +2.210.0010.0030.0021487329847328946.1476_hypotheticalprotein
*191053___________ +1.47 +1.600.0010.0080.0022105131004336606.2009_negativeregulatorofCOPIIvesicleformation
192748___________ +1.42 +1.340.0020.0070.0051235817536165816.2536_transcriptionfactorinvolvedinargininemetabolism
194800___________ +1.18 +1.290.0060.0340.0081436816962185486.3059_Rim101pactivatingprotein
*191499___________ +1.56 +1.850.0010.0040.0033552355267657926.3544_
*195820___________ +2.99 +3.640.0000.0010.0011253837546455916.4039_GABA-specifictransportprotein
*195636___________ -6.10 -5.510.0000.0000.00026636124368764837846.4506_
*194512___________ +1.71 +1.620.0020.0070.0071642828146266246.4999_leucinerichrepeatgenefamilyprotein
*193733___________ -3.74 -5.320.0000.0020.00020952256043393486.5463_
195155___________ +1.07 +1.050.1910.1620.2631241813251130016.5943_
*191552___________ -4.44 -5.540.0000.0010.00014441032536260636.6408_
196715___________ +1.03 +1.020.9050.8920.7101278413118130986.6864_hypotheticalprotein
19872____________ +1.02 +1.030.4640.4500.3701286213108132686.7305_hypotheticalprotein
*193013___________ +2.12 +2.330.0000.0020.0012715457582632476.7750_septin
19952____________ +1.09 +1.110.0380.0960.0441379315037153636.8202_
*195395___________ +1.27 +1.380.0040.0170.0081733821958239096.8630_
*195959___________ +1.27 +1.480.0010.0090.0021764822347261326.9078_nuclearandnucleolarproteinwithpossibleroleinribosomebiogenesis
191841___________ +1.30 +1.260.0030.0040.0161274316585159966.119__
191009___________ +1.28 +1.260.0030.0050.0121272616247160046.611__hypotheticalprotein
191831___________ +1.25 +1.160.0030.0070.0131226615387142026.1221_hypotheticalprotein
194688___________ +1.24 +1.210.0040.0110.0091344716650163026.1767_
*193353___________ +1.56 +1.180.0060.0040.2223315251813390676.2295_possiblecomplexIintermediateassociatedprotein
194404___________ +1.14 +1.100.0110.0120.0571272214534139696.2824_hypotheticalprotein
195039___________ +1.48 +1.360.0010.0020.0031555823087211836.3316_rRNAprocessingprotein
*192563___________ +1.47 +1.560.0010.0040.0042717239904423926.3812_U4/U6snRNA-associatedsplicingfactor
*193539___________ -5.29 -3.890.0000.0000.000449585849801154606.4285_conservedhypotheticalprotein
195618___________ -1.08 -1.060.2270.2550.2173277530394308696.4777_vacuolarproteinsortingassociatedprotein
193865___________ +1.24 +1.340.0050.0160.0091337016640179226.5254_
191254___________ +1.14 +1.060.1260.0680.4423357338199355316.5721_componentofCOPIIcoatofER-golgivesicles
192495___________ +1.28 +1.280.0040.0090.0101557319930199746.6176_1,3-beta-glucansynthase|targetforechinocandinantifungaldrugs
192963___________ +1.06 +1.030.9070.9000.7122655328170273096.6653_transcriptionalregulatoryprotein
191473___________ +1.06 +1.040.1920.1680.2561205912819125506.7101_
196566___________ +1.02 +1.030.6750.4230.8251337413660137356.7554_hypotheticalprotein
195017___________ +1.07 +1.160.0100.0480.0131849419812214456.7992_ureatransportprotein
*197118___________ -2.40 -2.430.0000.0000.0008151534024335676.8435_adenylatekinase
*196760___________ +1.61 +1.900.0020.0070.0041524424503289116.8871_negativeregulatorofearlymeioticexpression,requiredforgrowthatalkalinepHandinhighconcentrationsoflithiumchloride
42686____________ +1.04 +1.040.2400.2480.2401485515429154724.2686_
194650___________ +1.32 +1.200.0030.0040.0231363417984163746.304__
693______________ +1.35 +1.130.0040.0050.0281290817468146456.930__
*192803___________ -1.56 -1.120.0010.0010.0792317721487622065336.1494_coprophyrinogenoxidase|hemebiosynthesis
194465___________ +1.28 +1.190.0060.0100.0261546219726183856.2032_hypotheticalprotein
19801____________ +1.50 +1.350.0060.0090.0281311619635177096.2550_telomereTTAGGGrepeat-bindingfactor
194555___________ +1.13 +1.090.0530.0300.3071261614228137056.3074_agglutinin-likeprotein4
*192458___________ +1.47 +1.320.0010.0040.0051908328011251756.3560_
193924___________ +1.22 +1.060.0130.0080.2271304015847138106.4052_conservedhypotheticalprotein
196211___________ -1.16 +1.000.1660.0980.4076624856875665146.4523_conservedhypotheticalprotein
*194208___________ +1.66 +1.580.0010.0030.0031700328206269466.5013_recombinationandDNArepairprotein
*193749___________ +5.79 +4.980.0000.0000.0001380237993656873286.5478_
195139___________ +1.08 +1.220.0740.1420.0784518848632550036.5959_hypotheticalprotein
191565___________ +1.01 -1.060.3220.5750.1921868818918175896.6422_dihydrouridinesynthaseoftRNA
*196729___________ +1.27 +1.250.0010.0020.0052784435373348006.6878_TIP120protein[Homosapiens
196933___________ +1.01 +1.000.3670.1820.8591394614016139656.7319_ResistanttoRapamycinDeletion2
193027___________ -1.07 -1.170.1350.7580.0664117038578353076.7764_generalRNApolymeraseIItranscriptionfactor
*19967____________ -1.31 -1.180.0130.0120.0783013722984256436.8216_mitochondrialnuclease
*195410___________ +1.51 +1.480.0010.0030.0031639424750241866.8646_possibleroleduringmitosis
*195943___________ -1.43 -1.370.0040.0060.0163054621396222996.9094_conservedhypotheticalprotein
195064___________ +1.12 +1.130.0130.0360.0211234813861139466.134__

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
191021___________ +1.07 +1.070.0610.0960.0821210912976129216.642__leucinerichrepeat
193173___________ +1.05 +1.080.0560.3140.0361248413046135006.1240_secretoryprotein
193290___________ +1.06 +1.070.0980.1400.1131213512869130046.1780_NADH:ubiquioxidoreductase
191961___________ +1.01 +1.030.6680.7870.4391219112291125256.2315_conservedhypotheticalprotein
194964___________ +1.00 -1.020.9450.9520.7731234812410120606.2841_conservedhypotheticalprotein
19705____________ +1.02 +1.000.7110.4380.9921221712464122536.3329_histoneacetyltransferase
195288___________ -1.20 -1.250.0320.0690.0462157617918173116.3827_Zn-containingalcoholdehydrogenase
19292____________ +1.00 -1.020.9890.9120.9371344413455131616.4300_
192681___________ -1.04 +1.010.7550.4920.9001193111486120126.4791_ribonuclease,T2family
196547___________ +1.10 +1.120.0530.1640.0471460016067164076.5267_hypotheticalprotein
191659___________ -1.03 -1.030.3260.3560.2691236511988119526.5734_glycosyltransferase
195764___________ -1.04 -1.060.1530.2850.1191224611723115896.6194_antiviralprotein
192951___________ -1.03 -1.090.3070.2910.2942502124313228776.6665_homoserinedehydrogenase
191459___________ -1.02 -1.040.5130.3950.4921766917273169266.7114_carboxylmethylesterase|ribosomalproteinofthesmallsubunit,mitochondrial
196581___________ +1.05 +1.100.1060.2540.0821706817994188146.7569_conservedhypotheticalprotein
*195004___________ +1.27 +1.480.0010.0080.0021373017423202986.8005_DNA-dependentATPaseoftheSnf2pfamily
197105___________ -1.05 -1.040.2040.1030.5991274812122122936.8448_cyclin-dependentproteinkinaseinhibitor
196747___________ +1.09 +1.180.0700.0630.1571594817345187556.8885_
42801____________ +1.00 -1.020.9930.9220.9651226012290120544.2801_
*1971271__________ -1.20 -1.230.0430.1090.0473802931734309006.321__NA
19183____________ +1.15 +1.140.0160.0490.0221279614762146016.945__imidazoleglycerol-phosphatedehydratase
191818___________ +1.24 +1.130.0090.0180.0231251815571140996.1510_
193586___________ +1.27 +1.160.3420.5910.2031288416378149356.2046_conservedhypotheticalprotein
19109____________ +1.08 +1.140.0370.1250.0361281413889145946.2566_
19451____________ +1.12 +1.260.0120.0260.0251336115017167906.3088_highcopysuppressorofacyclicAMP-dependentproteinkinasemutant
192209___________ +1.36 +1.350.0030.0080.0101264517208170696.3575_iontransportprotein
194670___________ +1.15 +1.170.0110.0420.0161338615412156586.4065_
194373___________ -1.02 -1.120.1770.2330.1662114420673188716.4538_riboflavinkinase
193328___________ +1.10 +1.090.0460.0670.0761308914385142126.5026_transcriptionalregulatorofhyperosmoticresponse
196302___________ +1.05 +1.030.1260.1180.1951270613309131466.5496_
192034___________ +1.05 +1.020.5090.3980.4811209512737123686.5973_hypotheticalprotein
191636___________ +1.01 +1.020.7130.4600.8352220822397225496.6436_pheromoneresponsepathwayprotein
*195653___________ -7.50 -8.210.0000.0000.00013477021796221641756.6893_F1F0-ATPasecomplex,F1betasubunit
196948___________ +1.03 +1.010.8410.6260.8161954020140196806.7334_transmembraneCa2+transporter
193042___________ +1.06 +1.070.1960.2360.1881223412940130546.7779_hypotheticalprotein
193230___________ +1.12 +1.080.0500.0540.1101262714137136416.8230_RHOproteinsignaltransduction
195425___________ -1.05 -1.020.3020.1410.9337451971099728696.8661_conservedhypotheticalprotein
195929___________ -1.02 +1.000.9250.8130.7951224412006122776.9108_conservedhypotheticalprotein
193102___________ +1.31 +1.180.0020.0030.0161713122356202526.148__
194403___________ +1.24 +1.180.0030.0070.0121308616247154586.656__
192650___________ +1.29 +1.230.0040.0110.0111315717022161196.1259_
*192167___________ +1.62 +1.660.0010.0030.0022113834339350726.1804_conservedhypotheticalprotein
*191648___________ +1.21 +1.290.0030.0090.0072145026018276556.2332_DNArepairprotein
19929____________ +1.13 +1.060.0660.0480.2101329814966140456.2859_hypotheticalprotein
194647___________ +1.37 +1.340.0030.0070.0111365418764182616.3344_partialCCAAT-bindingtranscriptionfactor
*194883___________ +1.60 +1.740.0000.0010.0003053448928530556.3842_
194474___________ +1.15 +1.090.0130.0120.0801586818291173746.4313_conservedhypotheticalprotein
*19281____________ +1.28 +1.340.0010.0030.0022640333717354566.4811_
*193009___________ +1.29 +1.440.0010.0080.0022088426879301726.5280_hypotheticalprotein
*193583___________ +1.70 +1.900.0000.0010.0002561643575487776.5746_Ran-GTPase-bindingproteininvolvedinnuclearexport
196597___________ +1.01 -1.000.8100.7290.6381505615146150506.6209_hypotheticalprotein
*194532___________ -1.30 -1.080.0220.0130.2515433841948502546.6678_conservedhypotheticalprotein
191445___________ +1.29 +1.290.0040.0090.0141324917136170456.7128_regulatorofTy1Transposition|EstablishesSilentChromatin
196037___________ +1.20 +1.190.0030.0070.0111538718429183636.7581_conservedhypotheticalprotein
194988___________ +1.06 +1.060.1040.1030.1671435715281151906.8021_hypotheticalprotein
*197092___________ -1.53 -1.460.0020.0070.0047133846705489796.8461_conservedhypotheticalprotein
*197549___________ -1.27 -1.080.0230.0170.1482821622231260956.8897_dolichyl-phosphate-mannose-proteinmannosyltransferase
42876____________ +1.17 +1.100.0210.0370.0411201114087132494.2876_
194466___________ +1.23 +1.150.0170.0230.0521228615155141676.338__potentiallyinvolvedinpalmitoylationandlocalizationofsmallGTPases
193469___________ +1.25 +1.150.0080.0140.0261455918143166896.961__
192818___________ +1.36 +1.250.0040.0070.0221406119056175566.1524_
62068____________ +1.31 +1.150.0060.0080.0361286116804147336.2068_
194867___________ +1.32 +1.080.1450.0610.9801434018934155426.2583_
191309___________ +1.20 +1.150.0070.0090.0411471217702169506.3104_
*192758___________ +2.72 +2.710.0000.0000.0002768675326751576.3590_
*191959___________ -1.26 -1.120.0020.0030.0193176625186283496.4080_conservedhypotheticalprotein
*1953_____________ +1.66 +1.760.0010.0020.0022321638651408856.4553_U2AFsplicingfactorsmallsubunit
191964___________ +1.10 +1.090.0590.0390.2401232813621133996.5039_
*196317___________ +1.76 +1.820.0000.0000.0003140255190572516.5510_5'-phosphoribosylformylglycinamidinesynthetase
192046___________ +1.04 +1.020.1060.0500.5561291313437131086.5985_acetyl-CoAC-acyltransferase,peroxisomal|fattyacidbeta-oxidation
191620___________ +1.15 +1.030.0560.0270.4661314815126135886.6452_hypotheticalprotein
*195665___________ -1.23 -1.150.0100.0100.0643187825929278056.6905_conservedhypotheticalprotein
*194858___________ +1.33 +1.450.0100.0200.0251299617297189036.7353_
193054___________ +1.20 +1.130.3060.1750.5542034524447228906.7791_26Sproteasomesubunitofendopeptidase
*193243___________ -1.16 -1.280.0100.0180.0282596222369202866.8243_signalrecognitionparticle
*195437___________ +3.44 +5.210.0000.0000.000529541820732761266.8673_DL-glycerol-3-phosphatase
195915___________ +1.04 -1.010.4230.2150.8861339013929133136.9122_ureaactivetransportprotein
196382___________ -1.03 -1.040.4620.4340.3791172611332113046.13___
192721___________ +1.22 +1.150.0070.0100.0321271015443146696.676__
*19333____________ +2.24 +1.860.0010.0020.0041277428647237466.1275_
192885___________ +1.32 +1.170.0240.0160.2101426518849166786.1820_DNA-directedDNApolymerasealpha,DNAprimasesubunit
192538___________ -1.06 -1.060.1140.2310.0961167411004110016.2347_
193700___________ +1.05 +1.040.9620.8050.9572062721602215176.2877_mitochondrialoutermembranespecializedimportreceptor
196498___________ -1.10 -1.080.0670.1020.0891158610506107246.3362_
*192392___________ +2.28 +1.780.0010.0030.0042612959553465116.3856_hypotheticalprotein
*193402___________ -1.02 -1.270.0160.5240.0099271590725728156.4329_conservedhypotheticalprotein
*19605____________ +1.21 +1.110.0100.0110.0531570419056174936.4826_hypotheticalprotein
*191361___________ -1.23 -1.300.0290.0540.0496010248941463176.5293_
*193568___________ +1.54 +1.330.0010.0030.0052036331297270346.5761_conservedhypotheticalprotein
196612___________ -1.05 -1.100.2550.7810.1293215730652292656.6225_
194544___________ +1.12 +1.060.0170.0130.1331481016532157686.6690_hypotheticalprotein
*196877___________ +1.54 +1.450.0050.0070.0271137781749221649186.7140_
*196049___________ +1.68 +1.400.0020.0040.0132474741606345646.7595_
*197136___________ +1.90 +1.990.0010.0030.0021676231860332766.8034_
*197078___________ -1.28 -1.600.0010.0110.0024316533619270466.8475_conservedhypotheticalprotein
197563___________ +1.16 +1.050.5380.5030.4243808244313401576.8911_geranylgeranyltransferasetypeIIbetasubunit
43071____________ -1.00 -1.040.2700.9130.1341193511878114854.3071_
*194257___________ +2.11 +1.800.0010.0020.0041582033304285136.358__
196243___________ +1.28 +1.220.0040.0080.0121286716515157376.983__
*192454___________ +1.91 +1.630.0010.0020.0031721632838280606.1541_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194735___________ +1.06 +1.050.1820.0790.9681846019546193556.2086_putativeornithinecyclodeaminase
19131____________ +1.42 +1.400.0010.0050.0021500421313210676.2601_hypotheticalprotein
*191707___________ +1.97 +1.830.0000.0010.0011603631545293436.3120_hypotheticalprotein
192788___________ +1.19 +1.090.0160.0100.2081329615789144516.3605_
*191755___________ +1.31 +1.240.0040.0070.0132931638303363776.4094_transcriptionalrepressorcontainingaSETdomain
*64566____________ -1.77 -1.940.0000.0000.000179323101091922336.4566_
195861___________ +1.06 +1.020.1200.0690.3842353224870240216.5053_cellwallsynthesisprotein|cellwallbeta-glucanassembly
*196336___________ +1.24 +1.270.0050.0180.0091978224606251976.5526_
*196458___________ +1.45 +1.580.0000.0020.0011983328817312376.6001_conservedhypotheticalprotein
193440___________ +1.17 +1.200.0040.0110.0111336115612160986.6465_putativetransporter
193126___________ -1.22 -1.090.0570.0520.1456605354231604506.6919_cytoplasmicchaperoninoftheCctringcomplex
*194843___________ +3.17 +3.160.0000.0000.0002205569963697026.7368_conservedhypotheticalprotein
*193066___________ +2.01 +1.880.0000.0010.0003569271891672146.7803_endo-1,3-beta-glucanase
*193256___________ +1.71 +1.690.0070.0140.0191395623859236546.8257_
195449___________ +1.15 +1.040.2550.1270.6685185459854540546.8685_peroxisomalmembraneprotein
195902___________ -1.01 -1.040.5790.7680.3611190911752114086.9135_GTP-bindingproteinoftheRasfamily
*19173____________ +1.83 +1.490.0010.0020.0071618829646241326.51___
19255____________ +1.39 +1.310.0050.0080.0181333318588174976.693__
*191990___________ +1.63 +1.470.0010.0020.0041635826646239776.1292_SortingNeXin
194636___________ +1.24 +1.150.0070.0070.0521329316435153166.1838_hypotheticalprotein
*19267____________ +1.93 +2.030.0000.0010.0012631950767532996.2361_
192882___________ +1.51 +1.220.0040.0060.0311231118588150006.2894_highlyconservedhypotheticalprotein,putativepurinepermease
*195059___________ +1.89 +1.850.0000.0000.0002361444618437796.3377_
1963132__________ +1.23 +1.090.0110.0080.1171270115612138456.3874_NA
192199___________ -1.02 -1.140.0400.2350.0291982519435174126.4342_inorganicphosphatetransporter
191720___________ +1.18 +1.100.0140.0140.0661489617550164386.4840_conservedhypotheticalprotein
65307____________ +1.16 +1.060.0460.0250.3561231114254130576.5307_
196345___________ +1.19 +1.170.0120.0160.0441860822134217146.5774_translationinitiationfactoreIF3
*196103___________ +1.74 +1.710.0000.0010.0011784430959305636.6238_similartoproteininvolvedinsporulation
*19814____________ +1.66 +1.540.0010.0020.0041700028143261516.6705_transcriptionalregulatorofmultipleaminoacidpermeases
196893___________ +1.21 +1.180.0170.0460.0251566418917184366.7156_
196063___________ +1.02 +1.010.6060.3480.9242081621173210456.7607_deubiquitinatingenzyme
*197152___________ -1.60 -1.360.0010.0020.00510421665186767516.8052_cysteinesynthase
*197064___________ +1.84 +2.210.0000.0000.0004249678000938916.8489_glutaminyl-tRNAsynthetase
*197577___________ -2.60 -2.590.0000.0000.0007856030251303526.8925_proteininvolvedinmaturationofCOX1andCOBmRNA
PHR1_____________ +1.04 +1.020.3820.2300.573122931278312535PHR1___
191698___________ +1.15 +1.100.0560.0370.2311204113843132296.375__
192549___________ +1.20 +1.120.0130.0130.0741504618106168736.1005_
194972___________ +1.05 +1.030.2390.1600.3941256813258129416.1555_
193412___________ +1.05 +1.030.5070.2780.8411228012876125956.2101_lipaseinvolvedinautophagy
194157___________ -1.13 -1.170.0140.0340.0251823416185156086.2621_peroxisomal2,4-dienoyl-CoAreductase
*191161___________ +1.39 +1.290.0020.0040.0081802425062233156.3136_
192440___________ +1.14 +1.060.0540.0280.3881193413596126026.3619_cullin,ubiquitinligaseactivity
192587___________ +1.10 -1.010.0640.0270.7991243213710123426.4111_
192812___________ -1.03 +1.020.3580.1930.6711900118476193546.4581_nitrosoguanidineresistance|drugtransporter
195605___________ +1.05 +1.050.1910.1000.5361705517830178766.5067_conservedhypotheticalprotein
192307___________ -1.18 -1.060.0100.0070.1932698422849254086.5543_polyadenylationfactorIsubunit2
19730____________ -1.03 -1.040.3860.7170.2171237012024118526.6013_GTPaseactivatingprotein(GAP)forRho
193667___________ +1.10 +1.010.0930.0390.8671193013116120866.6478_kinesin-relatedprotein
193114___________ +1.49 +1.300.0020.0040.0121308519536170656.6931_pseudouridylatesynthase
*194828___________ -1.60 -1.350.0010.0030.0056591341166486466.7383_hypotheticalprotein
196437___________ +1.03 -1.020.5110.2730.9771266213015124666.7817_componentofanaphase-promotingcomplexrequiredformitosisandRNAsynthesis
193269___________ +1.02 +1.010.4380.2300.8201232612628124326.8269_
*195465___________ +1.17 +1.220.0020.0100.0032271026458277106.8701_conservedhypotheticalprotein
195887___________ +1.22 +1.200.0060.0110.0191744721365209496.9150_nuclearporeprotein
19151____________ +1.05 +1.060.1410.1420.1891264413335133906.76___
*191236___________ +1.80 +1.460.0030.0050.0151470326424214506.710__
191507___________ +1.56 +1.330.0010.0030.0061427522303189976.1307_AntagonistofMEN(MitoticExitNetwork)|chromosomestability
191529___________ +1.27 +1.160.0510.0260.4261320316766152946.1856_hypotheticalprotein
*192021___________ +4.99 +4.710.0000.0000.000817604077183853576.2378_
*19171____________ +1.69 +1.410.0010.0030.0091705328859239846.2907_DEADboxRNAhelicase
191523___________ +1.23 +1.120.0060.0060.0531496018430167926.3390_
191334___________ +1.49 +1.360.0060.0110.0201413221069191986.3887_hypotheticalprotein
*195507___________ +1.32 +1.280.0080.0260.0142783636698355776.4355_rRNAprocessing
*195782___________ +1.20 +1.400.0060.0340.0084626855660649386.4854_phospholipase
196160___________ -1.09 -1.120.2670.9200.1321167410741104356.5319_
196360___________ +1.09 +1.020.1030.0480.5971232813386125726.5789_conservedhypotheticalprotein
196086___________ -1.14 -1.140.0330.1030.0351169310247102826.6255_2-isopropylmalalatesynthase
19829____________ -1.12 -1.140.0100.0370.0151167410386102836.6720_serine/threonineproteinkinase
196906___________ -1.22 -1.140.0090.0140.028121529989106986.7170_WDrepeatproteinthatinteractswiththetranslationalmachinery
196076___________ -1.17 -1.130.0100.0210.023116749937102876.7620_involvedinendosometogolgiproteintransport
197165___________ -1.15 -1.140.0060.0160.0141194810385104966.8065_hypotheticalprotein
197052___________ -1.16 -1.160.0190.0360.0381230210648105746.8501_phosphatidylinositolphosphatephosphatase
197592___________ -1.18 -1.130.1760.7280.0881243510534110236.8940_long-chainfattyacid--CoAligaseandsynthetase4
*1997_____________ +1.81 +1.780.0010.0020.0021496227034265656.389__
61028____________ +1.14 +1.120.0200.0200.0801221513913136986.1028_
193491___________ +1.14 +1.080.0360.0300.1411220213880131576.1571_
*192017___________ +2.47 +1.940.0010.0030.0051510237297293016.2115_RNApolymeraseIalphasubunit
19716____________ +1.14 +1.120.0250.0230.1071257014299141296.2637_similartopore-formingbacterialSepticolysin
*194716___________ +3.27 +2.640.0000.0000.0002647086531698826.3152_NADP-glutamatedehydrogenase
19756____________ +1.16 +1.060.0130.0100.1211253814519133426.3635_secretedaspartylproteinase7
195556___________ +1.11 +1.110.0620.0840.0961350214992150246.4126_hypotheticalprotein
194757___________ +1.28 +1.320.0030.0110.0071828023313242046.4598_nucleararchitecturerelatedproteinwithhomologytohumanNarf(NuclearprelaminARecognitionFactor)
*191233___________ +1.60 +1.640.0000.0010.0012993948028491016.5084_amidophosphoribosyltransferase
192676___________ +1.05 +1.060.2070.1950.2432785729116294496.5558_RNApolymeraseIIelongatorassociatedprotein
196267___________ +1.19 +1.100.0590.0490.1641251814851137086.6026_conservedhypotheticalprotein
*19422____________ +2.74 +2.570.0010.0040.0032354264430604606.6491_
193098___________ +1.14 +1.080.0380.0280.1681323015065143416.6947_RNAhelicase-relatedproteinrequiredforpre-mRNAsplicing
193986___________ +1.08 +1.020.1790.0780.8671270713680129876.7398_
*196422___________ +1.25 +1.310.0130.0450.0194489056249586536.7832_sulfonylureaherbicidesensitivity|partofanextracellularaminoacidsensor
193284___________ +1.02 -1.000.5870.3900.6561321613525131946.8284_hypotheticalprotein
*197466___________ +1.75 +1.910.0000.0030.0011658829059316206.8717_
*195871___________ +1.88 +1.710.0050.0100.0161746832759298666.9165_
192454___________ +1.34 +1.210.0050.0060.0311289617236155766.104__
192859___________ +1.28 +1.160.0050.0070.0301412218009164086.731__
192229___________ +1.41 +1.280.0020.0040.0141264917814161876.1322_zinc-fingerprotein
193484___________ +1.40 +1.160.0040.0040.0701396419593162626.1871_signalrecognitionparticlereceptor
195285___________ -1.42 -1.410.1120.2290.0944535131843322216.2391_flavodoxin
*195746___________ +1.99 +1.750.0050.0110.0151303925986227846.2925_alanyl-tRNAsynthetase
195124___________ +1.31 +1.210.0030.0050.0191289516840155906.3408_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
19414____________ +1.31 +1.170.0050.0060.0351318417265154316.3901_mitochondrialribosomesmallsubunitcomponent
*193508___________ -1.27 -1.450.0020.0090.0053846330264265916.4368_hypotheticalconservedprotein
*192994___________ -1.41 -1.160.0070.0100.0272300391627591978526.4871_ribosomalprotein
*191588___________ -1.61 -1.560.0000.0000.0006367939491407636.5332_conservedhypotheticalprotein
19993____________ +1.11 +1.060.0910.0470.4301331314770140606.5805_conservedhypotheticalprotein
*19395____________ -2.04 -2.640.0010.0040.002241815211855919168326.6269_enolaseI
19522____________ -1.12 +1.010.1740.0810.6895714150919575696.6734_mitochondrialATP-dependentprotease
*196919___________ +1.61 +1.720.0010.0030.0022156034774370766.7183_hypotheticalprotein
*196527___________ +1.77 +1.910.0000.0000.0004198274436803536.7633_pheromone-regulatedmembrane
*197181___________ -1.27 -1.130.0080.0100.0373442827131305636.8080_
*197354___________ +1.20 +1.150.0090.0120.0362654831835306076.8514_longevity-assuranceprotein
*197604___________ +1.51 +1.470.0000.0010.0021999030160293256.8952_targetingcomplex(TRAPP)componentinvolvedinERtoGolgimembranetraffic
19715____________ +1.05 +1.030.3300.1880.5801197712522122786.409__hypotheticalprotein
195614___________ +1.01 -1.040.2810.3800.2082159021786207176.1048_
193071___________ +1.15 +1.060.0300.0250.1351234014195130556.1590_
193663___________ +1.07 +1.030.1040.0490.5761229213205126596.2134_
1918_____________ +1.05 +1.050.4150.2120.8671638017276172766.2651_inosine-5'-monophosphatedehydrogenase|guanosinenucleotidebiosynthesis
194320___________ +1.14 +1.060.0580.0760.0951248814279132686.3172_hypotheticalprotein
194190___________ +1.02 +1.000.9140.7430.8421454214863145866.3647_similartodnaJchaperones
195378___________ +1.02 +1.020.6730.5550.5671949619880198016.4140_20SproteasomesubunitYC7ALPHA/Y8
194310___________ +1.03 +1.030.5380.4740.4461216412542124936.4615_hypotheticalprotein
*196117___________ +1.10 +1.300.0040.0510.0052687629624350586.5098_membraneproteinsimilartoauxineffluxcarrier
192335___________ +1.05 +1.000.4540.2650.6701493715611149846.5573_highlyconservedhypotheticalprotein
196277___________ -1.00 -1.030.2230.1160.5741180011772114546.6037_
19437____________ -1.05 -1.060.1750.1700.2181327412617125516.6505_
195174___________ +1.14 +1.130.0140.0190.0471818920699206106.6962_TFIIDsubunit|RNApolymeraseIItranscriptionfactor
193999___________ +1.01 -1.000.5350.3960.5321592816012158706.7412_conservedhypotheticalprotein
196405___________ -1.00 -1.010.5830.3620.7231264812648125526.7849_conservedhypotheticalmembraneprotein
195308___________ -1.03 -1.100.0520.5540.0281432813945130326.8297_hypotheticalprotein
197481___________ -1.17 -1.190.0620.0750.1062474821071207356.8733_malatedehydrogenase
19164____________ -1.08 -1.080.0770.1660.0731190211027110646.157__
6749_____________ +1.32 +1.210.0040.0070.0181276816905153946.749__
191341___________ +1.60 +1.320.0030.0040.0231377922057181526.1343_serine/threoninekinase
*191575___________ +1.25 +1.150.0480.0280.2932838535532326426.1887_
194570___________ +1.31 +1.160.0020.0020.0171594620814185296.2406_hypotheticalprotein
191206___________ -1.12 -1.110.0180.0530.0251169810468105686.2940_
192187___________ +1.38 +1.290.0050.0100.0151395719308179706.3423_tunicamycinresistanceprotein|UDP-N-acetylglucosamine-1-phosphatetransferase
192509___________ +1.25 +1.110.0140.0100.1271283915999142596.3914_hypotheticalprotein
*192871___________ -3.44 -5.260.0000.0000.0006044681759201149826.4380_succinatedehydrogenase
191324___________ -1.22 -1.100.0120.0140.054116719599106236.4886_structure-specificnucleaseofthenucleotideexcisionrepairosome
191576___________ -1.14 -1.110.0360.0760.0491171710268105926.5344_hypotheticalRING-fingerprotein|homologtohumanbreastcancer-associatedproteinBRAP2
196369___________ -1.17 -1.170.0060.0260.0091285911009110346.5822_
195092___________ -1.18 -1.130.0070.0170.016116569919103396.6284_hypotheticalprotein
19536____________ -1.18 -1.150.0080.0180.018116729879101926.6748_TFIIDandSAGAsubunit
193301___________ -1.14 -1.140.0090.0240.0181158110139101276.7196_F-boxproteininvolvedinsulfurmetabolism
196512___________ -1.18 -1.110.0230.0330.0571198010120108056.7648_70kDaexocystcomponentprotein
197193___________ -1.09 -1.110.0240.0680.0321174210788105526.8093_leflunomideresistance
197366___________ -1.12 -1.120.6850.4920.6711161610406103276.8526_conservedhypotheticalprotein
197617___________ -1.22 -1.150.1190.5720.0641295810637112256.8965_proteinNalpha-acetyltransferasesubunit;transcriptionalsilencing
195045___________ +1.46 +1.210.0030.0030.0271284318703155336.427__
*191536___________ +1.61 +1.400.0010.0020.0041705227392239426.1061_zinc-andcadmiumresistanceprotein
191162___________ +1.05 +1.030.2500.1220.6892118822151217996.1611_aromaticring-cleavingdioxygenase
*191078___________ +2.13 +1.520.0000.0010.0041945041448295306.2149_alanineglyoxylateaminotransferase
*191777___________ +1.71 +1.560.0010.0020.0021769630324276926.2665_ubiquitin-specificprotease
*194722___________ +1.74 +1.670.0000.0010.0022353440976392066.3184_helix-loop-helix(bHLH)transcriptionfactor
19764____________ +1.36 +1.340.0210.0620.0291343618261180116.3664_
191685___________ +1.13 +1.110.2450.1190.6941259014213140056.4154_hypotheticalprotein
195710___________ +1.42 +1.340.0040.0090.0131562622137209976.4636_
196239___________ -1.02 -1.040.2180.4070.1451796017579172666.5117_
*192320___________ +1.51 +1.600.0020.0060.0042470837346396116.5588_proteinserinekinase
194939___________ +1.13 +1.080.0590.0470.1741331615073143656.6051_Monensin/BrefeldinAsensitivity
196624___________ +1.15 +1.180.0070.0210.0151440816580170526.6521_TBCdomainprotein
*195162___________ +1.34 +1.260.0010.0020.0052512433665317296.6974_serine/threonineproteinkinaseoftheMEKKfamily
*194012___________ +1.80 +1.570.0000.0010.0021679430149262856.7425_cyclin,associateswithPho85p
196387___________ -1.18 -1.260.0130.0290.0252542321627202336.7867_
*195322___________ +1.32 +1.260.0010.0020.0043422345167430436.8311_conservedhypotheticalprotein
*197494___________ +1.85 +1.540.0000.0010.0012034837674312656.8746_conservedhypotheticalprotein
195601___________ +1.31 +1.130.0070.0070.0571387818236157306.171__
195241___________ +1.47 +1.300.0020.0040.0151340719673174186.768__
*195569___________ +1.51 +1.280.0040.0050.0391720726010220016.1360_
19855____________ +1.32 +1.220.0020.0040.0111322017434161656.1904_hypotheticalprotein
194363___________ +1.28 +1.170.0060.0060.0581245915925145336.2425_
194492___________ +1.18 +1.070.0250.0230.1021476017396158246.2953_nucleolarprotein|requiredforpre-rRNAprocessingandribosomalsubunitassembly
191171___________ +1.24 +1.170.0070.0080.0411270615805148256.3438_S-adenosylmethionine:diacylglycerol3-amino-3-carboxypropyltransferase|lipidmetabolism
196022___________ +1.37 +1.190.0030.0030.0321357518582161696.3926_hypotheticalprotein
193197___________ +1.26 +1.170.0030.0060.0131688821287196816.4398_
*194791___________ +2.01 +2.080.0000.0000.0002679453915558666.4901_hypotheticalprotein
*191406___________ +1.58 +1.500.0010.0030.0041434222634215466.5359_hypotheticalprotein
196382___________ +1.11 +1.160.2070.5870.1141496616575173116.5835_
195074___________ +1.19 +1.150.0040.0070.0161596618930183886.6301_
*19550____________ -1.16 -1.180.0420.1010.0496796358652577706.6762_pyridoxine(pyridoxiamine)phosphateoxidase
*193314___________ +1.49 +1.500.0000.0020.0012162832149324736.7209_hypotheticalproteininvolvedinvesiculartransport
195281___________ -1.08 -1.050.1990.3260.1495393650118512596.7661_mitoticchromosometransmissioncontrol
197205___________ +1.14 +1.160.0130.0400.0201624818470188356.8105_ureaactivetransportprotein
*197378___________ +1.11 +1.220.0050.0200.0085096256501621606.8538_involvedincellcyclecontrolandionhomeostasis
197631___________ +1.11 +1.110.0270.0520.0451463416281162866.8979_conservedhypotheticalprotein
19634____________ +1.04 -1.020.5050.2790.8151201612540118346.445__
196488___________ +1.14 +1.090.0230.0300.0621181013467128286.1073_
192665___________ +1.19 +1.060.0350.0180.4001262215028133196.1628_supressorofsnf1mutation
191012___________ +1.10 +1.040.1540.0660.8911252213771130086.2168_AP-1clathrinassociatedproteincomplexsubunit
191246___________ +1.16 +1.060.0660.0400.2941227214250129496.2681_
*193215___________ +1.92 +1.850.0000.0010.0012204942378406866.3197_hypotheticalprotein
195221___________ +1.14 +1.040.0560.0230.9641342215242139156.3683_
191381___________ -1.01 -1.070.6330.7160.4253371933374314566.4167_possibleroleintheregulationofactincytoskeletalorganization
193546___________ -1.32 -1.150.0090.0120.0332628819853229506.4655_peroxisomeassemblyprotein(Peroxin-2)
196225___________ +1.18 +1.040.0470.0270.3021309815462136316.5131_cyclinlikeproteininteractingwithPHO85
191938___________ +1.04 +1.000.3490.1950.6191350114089135596.5602_
194170___________ -1.02 -1.030.5760.9640.3371283812596124726.6064_potentialcellwallprotein|memberofagroupofC.albicansorfsthatareweaklysimilartoScCIS3/PIR3/PIR1
196638___________ -1.05 -1.080.3380.2700.3702579624622238746.6535_ser/thrproteinphosphatasePP2C
*196838___________ -3.72 -2.870.0010.0020.0034563912265159056.6987_peroxisomal2,4-dienoyl-CoAreductase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194025___________ -1.11 -1.040.0640.0890.0952793425077268806.7438_endopeptidaserequiredformitosisandsporulation
194584___________ +1.01 -1.020.3110.1480.8591197012052117066.7883_acidphosphatase,secreted
*195337___________ +1.50 +1.380.0000.0010.0021670825137230646.8326_E2ubiquitinconjugatingenzyme
*197506___________ +2.04 +2.270.0000.0020.0011749235697397226.8758_conservedhypotheticalprotein
193337___________ -1.09 -1.070.0630.0920.0891167410738109086.188__hypotheticalprotein
194213___________ +1.60 +1.360.0020.0050.0121431722972195176.789__
*192298___________ -1.04 -1.330.0470.3120.0305871056486440316.1375_
192446___________ +1.23 +1.050.1000.0440.6672470330279259376.1919_highlyconservedhypotheticalprotein
*195227___________ +2.62 +2.870.0000.0000.0001903049832545886.2441_
194410___________ -1.13 -1.130.0270.1670.0221202010618106246.2972_beta-mannosyltransferase
*195209___________ +1.27 +1.180.0080.0110.0381922524469227206.3452_ConservedOligomericGolgicomplex6ComplexedwithCog8p
*195292___________ +3.56 +2.960.0000.0010.0012278781048674486.3942_polarityestablishment/cellularpolarization
*194048___________ -1.11 -1.440.0060.6100.004129599116453898076.4415_
*195732___________ +2.56 +2.840.0000.0010.00035458907001005866.4912_
192143___________ -1.11 -1.120.0140.0400.0231179410593105466.5374_
*193884___________ +2.22 +1.960.0010.0040.0041687237403330256.5854_
194388___________ -1.18 -1.170.0060.0150.01211610980899416.6318_
196668___________ -1.09 -1.100.0400.0600.0701184210860107316.6778_
19338____________ +1.03 +1.160.0760.1860.0671492815441172536.7222_conservedhypotheticalprotein
195268___________ -1.16 -1.120.0150.0290.0321258610864112636.7674_RNApolymeraseIItranscriptionfactor
197217___________ -1.22 -1.130.0060.0150.016118259660105066.8117_ribosomalproteinL4B
197389___________ -1.17 -1.170.1100.5450.0591227310472104996.8550_
197646___________ -1.18 -1.150.0100.0190.0261226010381106626.8995_
*19580____________ +1.29 +1.180.0010.0020.0132351630374277126.465__
191616___________ +1.13 +1.110.0180.0210.0661529917231169806.1089_
*193144___________ +3.43 +3.230.0010.0040.0031542652902498916.1641_MajorRepeatSequence
194734___________ +1.41 +1.330.0010.0030.0031684523681223296.2187_
*192722___________ +1.18 +1.240.0020.0050.0042202625937273626.2697_putativelyinvolvedingrowthregulation
19468____________ +1.07 +1.030.1430.0710.5501289913840132286.3213_hypotheticalprotein
637______________ +1.18 +1.140.0260.0310.0731337115844152906.3700_
195488___________ +1.33 +1.290.0160.0530.0231514720126195796.4182_similartopeptidechainreleasefactor
*192570___________ -2.95 -3.050.0000.0000.00019738666878646526.4671_putativeNADH-ubiquinoneoxidoreductase
193902___________ +1.34 +1.260.0050.0080.0191366418375172166.5146_hypotheticalprotein
*191854___________ +6.44 +4.440.0000.0000.000237458152992210549296.5621_histoneH4
*194184___________ +1.50 +1.460.0010.0020.0022489837293363386.6078_clathrincoatassemblyprotein
*196652___________ +1.47 +1.700.0010.0070.0031648224274280736.6548_
196851___________ +1.19 +1.100.0090.0080.0841434517109158456.7000_chromosomesegregationprotein
*194040___________ +1.43 +1.460.0000.0020.0012777639594406736.7452_
194599___________ +1.03 +1.030.5240.3540.5871214412495125606.7897_
*195352___________ -1.28 -1.360.0020.0040.0116550251007481246.8341_conservedhypotheticalprotein
197520___________ -1.04 -1.140.0710.7510.0352391023071209026.8772_peroxysomal3-ketoacyl-CoAthiolaseA
*195622___________ +4.49 +4.920.0000.0010.0011695576187834746.204__
191173___________ +1.25 +1.200.0080.0110.0291263915754152296.813__ubiquitin-proteinligase(E3)
192429___________ +1.39 +1.250.0020.0030.0231385919299173806.1392_hypotheticalprotein
*19551____________ +1.05 +1.160.0490.2940.0322610827352303916.1932_sharescarboxy-terminaldomainofphosphatidylserinereceptor
*196261___________ +1.41 +1.280.0040.0080.0171538221628196636.2455_
*191111___________ +2.18 +2.390.0000.0010.0003976486553949416.2987_
*191114___________ +1.02 +1.330.0070.1390.0065676458068754466.3466_conservedhypotheticalprotein
193762___________ +1.35 +1.270.0030.0060.0151359218376172206.3957_hypotheticalprotein
*195591___________ -1.58 -1.490.0090.0140.0324122826032276456.4432_
191063___________ +1.21 +1.070.0100.0080.1241434517367153546.4926_conservedhypotheticalprotein
*196170___________ +1.52 +1.380.0010.0020.0092425336914335516.5391_microtubule-associatedproteinrequiredformicrotubulefunctionduringmatingandmitosis|nuclearfusionprotein
193132___________ +1.09 +1.140.1930.2870.1583635839648414376.5869_transmembranecationantiporterinvolvedinzincionhomeostatisandmeioticrecombination
*195118___________ +1.22 +1.450.0070.0260.011918321123891333936.6332_spindle-polebodyprotein
*196683___________ +1.16 +1.270.0220.0710.0273314838356420806.6792_
*19351____________ +1.20 +1.130.0060.0080.0302040524547230896.7235_conservedhypotheticalprotein
195256___________ +1.17 +1.050.0150.0100.1801317915474138666.7686_similartomammalianintegrin
*197232___________ +1.80 +1.790.0010.0030.0022186839451390936.8132_
197403___________ -1.08 +1.090.7310.8280.4945612352099609596.8563_conservedhypotheticalprotein
197663___________ -1.02 +1.100.4250.8320.2323668736021403126.9011_conservedhypotheticalprotein
191119___________ +1.09 +1.080.0500.0310.2591219513328132276.487__
*194776___________ +1.34 +1.360.0020.0040.0051970626444267906.1106_
*193149___________ +1.99 +2.040.0000.0000.0002710953959553606.1659_LongchainbaseStimulatesPhosphorylation
196248___________ +1.10 +1.030.2780.1300.8321270113921130746.2200_hypotheticalprotein
19644____________ +1.05 +1.040.1440.0850.3841181312378122756.2714_
193940___________ +1.05 +1.030.2290.1530.3871447615151149386.3227_
*196478___________ +2.14 +2.100.0000.0020.0011946941647408896.3716_glutathiones-conjugatetransporter
194505___________ -1.00 -1.030.7000.9810.4431382613815134706.4197_alcoholdehydrogenase
192584___________ +1.12 +1.150.0500.0740.0791641618375187996.4685_
19212____________ +1.27 +1.210.0010.0040.0041659821124201326.5161_endosometovacuoletransportfactor
19322____________ +1.14 +1.080.0330.0220.1981307014936140656.5636_hypotheticalprotein
*192172___________ +1.66 +1.810.0000.0020.0002305838171417436.6091_D-arabinosedehydrogenase
*19671____________ +1.97 +2.130.0000.0010.0012638052082561916.6564_conservedhypotheticalprotein
196863___________ +1.13 +1.230.2800.5900.1603436638722423796.7012_V0domainofvacuolarH+ATPase
192090___________ +1.09 +1.170.1300.7630.0645648761405658726.7465_partofsmall(ribosomal)subunit(SSU)processosome(containsU3snoRNA)
194612___________ +1.16 +1.050.0270.0140.3481432716673150676.7911_endo-1,3;1,4-beta-D-glucanase
195368___________ +1.01 +1.030.7360.4910.8161274212822130756.8357_conservedhypotheticalprotein
*197538___________ +1.38 +1.490.0030.0090.0071835825409273826.8790_DNArepairandrecombinationprotein
*192781___________ +1.83 +1.580.0020.0040.0152090238184330156.15___
*19454____________ +2.06 +1.940.0000.0010.0012305447497448396.508__
19232____________ +1.12 +1.080.0130.0150.0521195513333129456.1124_
*192823___________ +2.51 +2.870.0010.0030.0021821445714522276.1680_
*196472___________ -2.62 -3.220.0000.0000.00023627090257734586.2215_
*193418___________ +1.72 +1.610.0020.0040.0071452525044234256.2731_
*195569___________ +2.01 +2.350.0010.0040.0031513430378355276.3241_
*193087___________ -1.30 -1.740.0000.0040.0001851131428351065036.3734_smallsubunitribosomalprotein
*193753___________ +1.31 +1.130.0090.0100.0504738262296536656.4213_zincfingertranscriptionfactor
192742___________ -1.01 -1.060.5730.7430.3612428424070229576.4698_
*192417___________ +1.45 +1.400.0000.0020.0022388634706335166.5176_structuralmaintenanceofchromosomesprotein
*193974___________ -3.34 -3.780.0000.0020.0015858817532154926.5650_1-pyrroline-5-carboxylatedehydrogenase
193415___________ +1.00 -1.060.8530.6040.9537008670359664066.6110_
*192770___________ +2.35 +2.270.0000.0000.0003492681926794396.6582_hypotheticalprotein
*191896___________ -3.69 -4.810.0000.0010.0008441622880175506.7026_
*192075___________ +2.60 +2.360.0000.0000.000456461185571075016.7480_filamentousgrowth,cellpolarityandelongation
*194626___________ +1.15 +1.020.0250.0110.7201531317664156226.7925_TORsignaltransductionpathway|associateswithPp2apandSit4pproteinphosphatasecatalyticsubunits
197290___________ -1.02 -1.090.5180.5930.3558540783720782196.8371_Sm-likeprotein;partofcomplexinvolvedinmRNAdecay
196827___________ +1.16 +1.210.1610.4070.1011462116890177486.8804_pre-mRNAsplicingfactoraffecting3splicesitechoice
Cachs2___________ +1.01 +1.020.5610.3120.918122801240312554Cachs2_
*191010___________ +1.49 +1.370.0010.0040.0031598023776218326.220__
*191936___________ +1.45 +1.360.0020.0040.007796581152811083486.832__

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*191975___________ -1.20 -1.250.0030.0130.0054687839210375766.1409_componentofU4/U6.U5pre-mRNAsplicingcomplex
193518___________ +1.02 +1.120.3930.6680.229984811001871103306.1951_mitochondrial2-oxodicarboxylatetransportprotein
192160___________ -1.02 -1.000.9560.7920.9413032829771302876.2474_
*191095___________ +1.98 +1.680.0000.0000.0012586751128434116.3002_nuclearporeprotein
*194274___________ +1.83 +1.650.0010.0020.0031335024479219656.3483_
*194245___________ +1.49 +1.400.0010.0030.0032318634474324216.3979_conservedhypotheticalprotein
*19310____________ +1.43 +1.490.0010.0040.0042084229773310146.4448_
*192850___________ +2.01 +1.790.0020.0050.0064403888482788756.4944_
*196185___________ +1.67 +1.840.0000.0010.0002755145962507896.5406_hypotheticalprotein
*192261___________ +1.58 +1.570.0000.0010.0014029963873631836.5885_spliceosome-associatedessentialprotein
*195102___________ +2.14 +2.460.0070.0140.0201779838089437776.6348_
196699___________ -1.06 -1.080.1190.1490.1434489642158414746.6808_histidinolphosphatase
194439___________ +1.07 +1.130.0240.0810.0281621317288182716.7252_hypotheticalmembraneprotein
195243___________ -1.02 +1.020.5380.7070.3383854637639392726.7699_anthranilatesynthase/indoleglycerolphosphatesynthase,tryptophanbiosynthesis
*197247___________ +1.69 +1.480.0000.0010.0023136352946465426.8148_
197417___________ -1.05 -1.120.0550.1420.0531283325122490511408776.8578_
*197678___________ -4.36 -4.940.0000.0000.0007359851687201490106.9025_
195126___________ -1.10 +1.010.0650.0300.5503629233046368226.38___
6527_____________ +1.29 +1.170.0040.0070.0201269616320148436.527__
*191369___________ +1.60 +1.330.0010.0010.0051875029952249156.1149_
*194330___________ +1.35 +1.280.0040.0070.0131585821408202926.1694_
*191800___________ +1.99 +2.090.0000.0000.0003741874610782256.2232_involvedinvacuolartargeting
193637___________ +1.13 +1.120.0460.0450.1201236013999138876.2752_hypotheticalprotein
*194328___________ +1.87 +1.920.0000.0000.0004008175118768596.3258_copper-transportingATPase
19844____________ +1.36 +1.260.0020.0040.0111485420129186586.3749_
194895___________ -1.29 -1.280.0050.0150.0122526419588197156.4231_hypotheticalprotein
*194660___________ -1.52 -1.600.0010.0030.0043956332601772479426.4711_ribosomalproteinS6A(S10A)(rp9)(YS4)
*194294___________ -1.72 -1.720.0000.0000.0004520026255262156.5192_involvedinimportofcytochromec
*196151___________ +1.17 +1.380.0030.0590.0033690443332508066.5663_Arpcomplexsubunit
192899___________ +1.23 +1.140.0060.0090.0261588019573181496.6123_peroxisomal2,4-dienoyl-CoAreductase
*194250___________ -1.92 -2.260.0000.0020.0014634624128205216.6595_
191880___________ +1.02 +1.020.7840.7980.5642178422315222336.7041_
*192063___________ +1.18 +1.310.0010.0160.0023350739569440436.7492_conservedhypotheticalprotein
197013___________ +1.01 +1.000.9200.9890.7191651316703165646.7939_hypotheticalprotein
197303___________ +1.14 +1.230.0040.0120.0111891221565232916.8384_hypotheticalprotein
196811___________ -1.00 -1.020.8050.5750.8181358413556132746.8820_mitochondrialproteinrequiredforironmetabolism
Cafks3___________ +1.04 +1.070.4870.2830.705123241286413134Cafks3_
*192970___________ +1.80 +1.930.0010.0040.0031659629793320646.240__
191212___________ +1.31 +1.250.0030.0050.0221394518211174986.844__
19458____________ -1.00 +1.040.4820.8430.2712070620695214516.1428_
196027___________ +1.40 +1.230.0010.0020.0141441820142177156.1968_
*194069___________ +1.42 +1.390.0010.0030.0061475520884204876.2487_hypotheticalprotein
194060___________ +1.04 +1.150.2040.5250.1172786829115320026.3017_3-deoxy-D-arabino-heptulosonate7-phosphate(DAHP)synthaseisoenzyme|3-deoxy-D-arabino-heptulosonate7-phosphate(DAHP)synthaseisoenzyme|2-dehydro-3-deoxyphosphoheptonatealdolase,tyrosine-inhibited
*195184___________ +1.91 +2.280.0000.0010.0002609849903595436.3496_GEFinpheromoneresponsepathway
*192930___________ +1.35 +1.540.0020.0060.0061499620235231026.3995_
195522___________ -1.11 +1.010.9720.8660.8963878734813390936.4464_hypotheticalprotein
*192475___________ +1.24 +1.340.0060.0330.0093089638452414766.4960_hypotheticalprotein
*196202___________ +2.31 +2.570.0000.0010.0011957045234503636.5423_
*192246___________ +2.40 +2.840.0000.0000.0001817743610515526.5900_conservedhypotheticalprotein
*191998___________ +1.36 +1.300.0010.0030.0041984827068258976.6362_hypotheticalproteinsimilartoBotulinumneurotoxintypeB
*194114___________ -2.40 -2.170.0000.0000.0005545123144255976.6822_long-chain-fatty-acidCoAligase|Lipidandfatty-acidmetabolism
*194451___________ +1.50 +1.720.0020.0060.0071533423061264326.7265_
196967___________ -1.09 +1.010.1670.0850.5483458131589347706.7713_mammalianintegrinanalogue
*197261___________ -1.64 -1.450.0010.0030.0047273944413500196.8162_
*197433___________ +2.19 +3.130.0000.0010.0013000365799938036.8592_
*195999___________ +1.91 +2.090.0020.0050.0061549629661323416.9040_
*1955_____________ +1.57 +1.470.0010.0020.0023032147455445276.56___
*193870___________ -1.49 -1.700.0000.0010.0008105754254476076.551__
193170___________ +1.01 -1.090.5780.6950.3773287633342302276.1165_
192547___________ +1.20 +1.150.0160.0170.0671259015168144696.1713_
192280___________ +1.31 +1.170.0590.0390.2391659621805193356.2247_
194222___________ +1.35 +1.310.0050.0100.0181339618109176156.2767_desensitizationtoalphafactorpheromone|GTPaseactivatingprotein
*192853___________ +1.78 +1.580.0000.0010.0022356841953373386.3277_hypotheticalprotein
193461___________ +1.14 +1.060.0430.0250.2771549417630164936.3764_
*191280___________ +5.78 +6.360.0000.0000.000455422631782895226.4245_translationinitiationfactoreIF3subunit
19579____________ +1.02 +1.040.8930.9700.6763520836048365486.4729_
*194281___________ +1.94 +1.710.0000.0000.001988821915901686846.5205_interactswithforkheadprotein
*196136___________ -2.76 -3.260.0000.0000.0006233222563191316.5678_mitochondrialribosomeproteinL4
195842___________ +1.02 +1.010.5780.4330.5521555315884156656.6136_sirohemesynthase/methioninemetabolism
*194236___________ +1.50 +1.610.0010.0030.0031613524252259096.6608_
191867___________ +1.14 +1.130.0130.0170.0481731219814195166.7053_permeaseofmajorfacilitatorsuperfamily
*193812___________ +1.24 +1.100.0130.0150.0562273928132251036.7507_regulatorproteininvolvedinpleiotropicdrugresistancethatformsaribosome-associatedcomplex|DnaJ/HSP70chaperone
*197025___________ +2.28 +1.980.0000.0000.00146770106430925026.7952_
*197316___________ +1.37 +1.350.0300.2140.0222837538889382606.8396_
*196798___________ +2.71 +2.310.0010.0020.0022670372442615676.8832_
Cassa2___________ -1.04 -1.050.3960.2090.752121631173711589Cassa2_
*191544___________ +1.59 +1.530.0010.0040.0031491323735227896.255__
192124___________ -1.02 +1.030.4940.7580.2913433533662353426.863__putativedehydrogenase
*19117____________ +1.72 +1.630.0000.0020.0021791230821291486.1445_
*19691____________ +4.52 +7.140.0000.0010.00016634752261188356.1984_glycerol-3-phosphatedehydrogenase
*19100____________ +1.42 +1.320.0020.0030.0131503921391198046.2503_triacylglycerollipase
193646___________ +1.34 +1.160.2240.1160.5831252351679691449136.3031_coppertransportprotein
*193962___________ +3.02 +3.110.0000.0010.0001704551465529856.3509_
*19699____________ +3.13 +3.420.0000.0000.0001851457874632586.4009_hypotheticalprotein
193182___________ +1.00 +1.000.8700.9350.6451743017442174886.4478_
*192462___________ +1.88 +1.810.0000.0010.0011875935180338926.4973_RNApolIItranscriptioncofactor
*196285___________ +2.70 +2.650.0000.0000.0002936379271778666.5435_proteinphosphatasetypeI
*194933___________ +2.38 +2.430.0000.0020.0011938946199471716.5913_oleatedelta-12desaturase
*191414___________ +1.22 +1.130.0080.0080.0521170881424611324616.6383_hypotheticalprotein
*194097___________ -1.27 -1.150.0050.0070.0233510627535306596.6839_hypotheticalprotein
19899____________ -1.21 -1.200.0050.0100.0172468020474206336.7278_mannose-P-dolicholutilizationdefect1protein|transmembraneprotein
*196980___________ +1.19 +1.130.0050.0080.0262723532319307156.7726_proteinkinasesimilartonitrogenpermeasereactivator
197275___________ +1.20 +1.180.0040.0090.0141505418031176986.8175_reversetranscriptase
197446___________ -1.13 -1.240.0540.1140.0613473830825279576.8606_methylene-fatty-acyl-phospholipidsynthase
195984___________ +1.01 -1.010.2550.8600.1261806018186178946.9054_
194652___________ +1.09 +1.150.0100.0220.0231238313483141826.77___
199132___________ +1.01 -1.000.7950.9490.5442248422641224286.570__ubiquinol-cytochromecoxidoreductasesubunit6
*19117____________ +1.60 +1.320.0020.0030.0091595525559210936.1184_
*19709____________ +1.16 +1.110.0070.0080.0402171625192240866.1729_20Sproteasomesubunit
*193758___________ +1.33 +1.160.0010.0020.0152309830757267846.2264_putativemembraneprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*193451___________ +2.12 +2.440.0010.0040.0041534432501374566.2788_
*193618___________ +4.19 +4.540.0000.0000.000304821277931382856.3290_
*194358___________ -1.50 -1.580.0020.0050.0063360722368212586.3780_
192212___________ +1.08 +1.010.2610.1350.6241795219454180656.4257_hypotheticalprotein
*192114___________ +17.29 +14.890.0000.0000.00084804146611412628606.4747_peroxisomalurateoxidase|uricase
194814___________ +1.04 +1.070.0690.0580.1741228912779131336.5220_hypotheticalprotein
*19585____________ -1.74 -1.910.0010.0040.0053358619285175466.5695_mitochondrialribosomalproteinofthelargesubunit
195830___________ +1.05 +1.110.0450.0510.0981833219222202916.6148_translocationofproteinprecursorsacrossER|Hsp70familychaperone
*195791___________ -2.63 -2.710.0000.0010.00118381669898679506.6624_
*19500____________ +1.13 +1.210.0120.0600.0152572028999312466.7071_translationinitiationfactor3(eIF-3)zetasubunit
*193827___________ -1.24 -1.350.0030.0100.0082991624033222316.7522_conservedhypotheticalprotein
*197038___________ +1.49 +1.690.0010.0040.0012745840924463476.7965_
197328___________ -1.02 -1.070.3670.6260.2161924518817180336.8409_Candidaalbicansp100homolog
*196786___________ +1.45 +1.470.0010.0030.0031581622961233246.8845_hypotheticalprotein
42026____________ -1.01 -1.050.9810.9130.8931178911697112794.2026_
*19225____________ +1.20 +1.220.0020.0040.0072540630543309326.275__hydroxyisocaproatedehydrogenase
*192743___________ +1.40 +1.250.0010.0020.0071680623602210346.886__
191492___________ +1.22 +1.120.0040.0050.0301302915897146276.1461_pre-mRNAsplicingfactor|U1snRNPprotein
191675___________ +1.20 +1.210.0030.0070.0081883822599228796.1997_conservedhypotheticalprotein
*192727___________ +1.55 +1.550.0010.0020.0121524223589236666.2519_glutaredoxin
194523___________ +1.11 +1.060.0710.0670.1521478116475157106.3048_5,10-methenyltetrahydrofolatesynthetase|folinicacidutilization
19639____________ +1.23 +1.190.0040.0070.0161511218545180146.3526_regulatesprocessingof27Spre-rRNA
194752___________ +1.29 +1.130.1600.1770.184889551150951005366.4022_zincfingertranscriptionfactor
*192832___________ -1.17 -1.070.0450.0360.1595167144094481556.4493_conservedhypotheticalprotein
*193474___________ +1.61 +1.540.0010.0020.0031672726909257866.4985_ser/thrproteinkinaseinvolvedinchromosomesegregation
194685___________ +1.07 +1.040.1170.0660.3971242813309128806.5451_hypotheticalprotein
*19198____________ -1.35 -1.400.0010.0040.0043393525153242906.5929_
*191428___________ +1.55 +1.390.0010.0020.0041619425072224356.6397_hypotheticalprotein
194085___________ -1.02 +1.120.3720.8280.1974979248759556876.6851_hypotheticalprotein
*19882____________ -1.63 -1.750.0000.0020.00110672665336608476.7293_
*196992___________ +1.70 +1.900.0010.0040.0041562726581296846.7738_multidrugresistancetransporter|similaritytoantibioticresistanceproteins
19940____________ +1.16 +1.090.0130.0100.1261581318342172146.8189_GTPase-activatingprotein
197458___________ -1.05 +1.040.1980.2110.2122154020539223926.8618_coiledcoilprotein
*195970___________ +1.19 +1.300.0020.0070.0061778021142230816.9067_ATP-dependentDNAhelicaseinvolvedinDNArepair
19923____________ +1.31 +1.220.0020.0040.0091296316957158116.99___
*192030___________ +1.51 +1.260.0010.0010.0103623854726457286.594__
*191526___________ +1.47 +1.490.0030.0080.0111317119322195986.1206_
*191180___________ -1.22 -1.320.0000.0040.0013240026587244686.1746_
*19470____________ +1.68 +1.690.0020.0080.0062462841394415456.2281_
191491___________ +1.05 +1.070.0640.1120.0771300013694139236.2805_
193658___________ +1.20 +1.170.0060.0090.0251321415852155196.3303_conservedhypotheticalprotein
195720___________ +1.09 +1.040.0700.0490.2241660618065173016.3799_monocarboxylatetransporterproteins
*192613___________ -2.22 -2.420.0000.0000.0003143031417571299086.4272_involvedincellwallbiogenesisandarchitecture
*192099___________ +1.40 +1.470.0050.0120.0141406219750206496.4761_
194142___________ +1.11 +1.040.1070.0540.4821771419610184456.5239_
*192980___________ +1.25 +1.370.0020.0070.0041786622354243916.5708_
192481___________ +1.08 +1.080.0580.0730.1001208613098130016.6162_hypotheticalprotein
*195805___________ -3.17 -3.830.0000.0000.00016728452833436856.6639_mitochondrialD-lactateferricytochromecoxidoreductase
*19486____________ +1.24 +1.140.0130.0120.0761699020992193586.7085_largesubunitofdynactincomplex
193843___________ -1.12 -1.230.0950.8240.0452424221639197286.7538_signalrecognitionparticlereceptor|ERprotein-translocationcomplexsubunit
195030___________ +1.37 +1.060.1480.0980.3284506461714477366.7979_proteininvolvedingenomestability
197342___________ +1.34 +1.380.0510.1690.0441426419158197336.8423_conservedhypotheticalprotein
*196773___________ +1.71 +1.850.0020.0060.0081492625554276846.8857_
42436____________ -1.04 -1.020.5490.3540.6491194111452116624.2436_
*193854___________ +1.73 +1.570.0010.0030.0021576027278246836.290__
191290___________ +1.34 +1.270.0010.0030.0071330317821168616.909__xylulokinase
*196465___________ +1.96 +1.860.0010.0020.0041543030210286776.1477_
19264____________ +1.23 +1.260.0030.0050.0111273815644160136.2012_
*192747___________ +1.62 +1.290.0010.0020.0091679927221216956.2537_regulatorofglucose-inducedgenes
194801___________ +1.15 +1.160.0090.0160.0251301015010150446.3060_tRNAisopentenyltransferase
191495___________ +1.23 +1.210.0040.0080.0141323316313160286.3546_
195820___________ +1.28 +1.250.0100.0130.0371271116331158876.4040_
*195639___________ -1.26 -1.260.0160.0430.02510260981212816566.4507_
*194511___________ +1.44 +1.300.0010.0020.0052466835632319556.5000_leucinerichrepeatgenefamilyprotein
*193735___________ +1.23 +1.090.0070.0060.0774053050054443026.5465_
195148___________ +1.43 +1.310.0030.0060.0181281818305168086.5944_
*191552___________ -9.47 -10.030.0000.0000.00092382797589921486.6410_cyclophilin(peptidylprolylisomerase)
*196716___________ +1.16 +1.340.0030.0220.0043394139329454796.6865_mRNAcapmethyltransferase
*19871____________ +1.33 +1.380.0040.0100.0131477619676203416.7307_
193014___________ +1.15 +1.030.1150.0490.7975007055781885142596.7751_14-3-3protein
19954____________ +1.13 +1.160.0160.0490.0231509917047175206.8203_DnaJsubfamilyAmember
*195397___________ -1.13 -1.270.0010.0140.0023648432193287616.8633_conservedhypotheticalprotein
*195958___________ +1.31 +1.290.0010.0020.0032100227471270806.9079_multidrugresistance|ABCtransporter
*196889___________ +1.21 +1.170.0020.0030.0192959635929345886.121__
191008___________ +1.30 +1.130.0070.0070.0611313617013148386.612__hypotheticalprotein
191089___________ +1.36 +1.190.0050.0080.0211349618357160296.1222_
194689___________ +1.17 +1.090.0100.0100.0751275314970139416.1769_
193352___________ +1.17 +1.070.0160.0110.1621258014756134916.2296_putativedehydrogenase
194427___________ +1.09 +1.100.0280.0310.0791232213471135606.2827_involvedinkinetochorefunctionandubiquitin-mediatedproteolysis|kinetochoreproteincomplexCBF3
195040___________ +1.27 +1.220.0080.0120.0341317016757160146.3317_componentofthekaryopherindockingcomplexofthenuclearporecomplex
192564___________ +1.32 +1.260.0030.0070.0101342117776169146.3813_conservedhypotheticalprotein
*193540___________ -1.27 -1.200.0050.0070.0296742452967559846.4286_ATP-dependentRNAhelicase
*195619___________ +1.47 +1.350.0010.0020.0061511422184204266.4778_hypotheticalprotein
193865___________ +1.05 +1.110.0270.0560.0431458115319161286.5256_
191255___________ +1.11 +1.090.0570.0430.1871312414608143286.5722_
192496___________ +1.05 +1.030.5040.3260.6041440915092147726.6177_transporterinvolvedinnitrogenutilization
192962___________ +1.08 +1.030.1360.0910.3111696818296174456.6654_hypotheticalprotein
*191471___________ -3.44 -3.960.0000.0000.00019203055840485126.7102_cytochromecoxidasesubunitIV
*196568___________ +1.87 +2.020.0010.0050.0041558429104314046.7555_
195016___________ +1.03 +1.030.4640.2540.7781302413421133656.7993_conservedhypotheticalprotein
*197116___________ -1.17 -1.210.0320.1560.0284699840019388036.8437_memberoftheRNApolymeraseII-associatedPaf1complex
*196759___________ +2.53 +3.060.0000.0010.0011846946732564426.8872_negativeregulatorofearlymeioticexpression
42696____________ +1.06 +1.070.6500.3860.9111406514845151084.2696_
192252___________ +1.24 +1.160.0050.0060.0311248615532144716.306__
191531___________ +1.32 +1.120.0040.0050.0341264816751141706.931__mRNA3'-endprocessingprotein
*192802___________ +1.20 +1.170.0060.0080.0292390028720280656.1495_
194466___________ +1.27 +1.180.0020.0040.0101304616527154026.2033_
*19801____________ +1.50 +1.450.0030.0060.0121989429778287966.2551_
194557___________ +1.14 +1.100.0260.0240.1091288414673141926.3076_spindlepolebodyprotein
192459___________ +1.37 +1.300.0010.0030.0051548021180200936.3561_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
193923___________ +1.11 +1.150.0170.0240.0481444116095165706.4053_conservedhypotheticalprotein
*196213___________ +1.18 +1.200.0020.0050.0053032235656364216.4524_
65014____________ +1.12 +1.080.0210.0180.1121264014198136926.5014_
192691___________ +1.16 +1.240.0040.0090.0111381616047171196.5480_
195138___________ -1.01 +1.010.8850.8730.6831590515724160486.5960_hypotheticalprotein
*191566___________ +1.19 +1.260.0040.0440.0052228626600280446.6423_U3snoRNPprotein|strongsimilaritytoS.pombebeta-transducin
196730___________ +1.05 +1.120.1550.3670.1032616727385293716.6877_
*196934___________ -2.01 -1.810.0000.0010.0013838619105211696.7320_proteintransport;pentamidineresistance
193029___________ +1.02 -1.040.6280.8740.3871523815507147026.7766_enpyl-CoAhydratase,mitochondrial
19968____________ +1.05 -1.010.2550.1150.9711272713344125606.8217_conservedhypotheticalprotein
*195411___________ +1.13 +1.180.0110.0560.0133198636045378246.8647_E2ubiquitin-conjugatingenzyme
195942___________ +1.02 -1.010.7030.4310.9701511515467149846.9095_inhibitorofTranslationTermination
*193661___________ -1.03 -1.390.0040.6770.0035718855417410906.135__
191022___________ +1.16 +1.110.0160.0260.0381338115543148856.643__leucinerichrepeat
19920____________ +1.16 +1.090.0120.0090.1221217114085133106.1242_
193291___________ -1.03 -1.080.5090.5720.3553432733186316956.1781_hnRNPmethyltransferase
*191960___________ +2.22 +2.150.0010.0020.0021811240252388976.2316_
194963___________ +1.09 +1.090.0280.0220.1331244213515135686.2842_proteinphosphataseTwoC-Interactingprotein
*194887___________ +3.79 +3.280.0000.0000.0001980475084648906.3331_calcofluorresistance|involvedincellwallbiogenesisandarchitecture
195289___________ +1.06 +1.060.0890.0960.1421203412765128016.3828_putativesteroidsulfotransferase
*19291____________ +1.83 +1.750.0000.0010.0012822451716493706.4302_involvedinproteinsumoylation
192684___________ +1.10 +1.060.0420.0290.1981272914051134706.4793_
*196544___________ +1.23 +1.170.0070.0070.0571440217707167926.5268_
65735____________ +1.02 +1.030.6710.4970.6351400114226143616.5735_
195763___________ -1.11 -1.140.0070.0330.0101998317927175886.6195_gluconatedehydrogenase
192949___________ +1.05 +1.030.1320.1070.2371391014635142616.6666_
*191458___________ +1.25 +1.300.0020.0050.0051884223579245366.7115_tRNA-specificadenosinedeaminasesubunit
*196582___________ +1.80 +1.630.0000.0000.0013747467574612676.7570_20SproteasomesubunitC1
*195003___________ +1.38 +1.370.0090.0140.0301260017404172046.8006_conservedhypotheticalprotein
*197104___________ +2.18 +2.040.0000.0000.0012634457489537916.8449_putativeGPI-anchoredmembraneprotein
196747___________ +1.57 +1.550.3390.7590.1822877245121446596.8884_conservedhypotheticalprotein
42811____________ +1.08 +1.080.0710.0520.2101211813073130464.2811_
*19364____________ +1.53 +1.360.0000.0010.0033307250466448796.323__
*19185____________ -1.39 -1.400.0030.0090.0093466624916246806.947__
*192657___________ +1.62 +1.290.0020.0030.0131486324049192116.1511_hypotheticalprotein
193589___________ +1.34 +1.170.0020.0030.0181339217951157256.2047_requiredforchromosomepairing
19107____________ +1.32 +1.280.0030.0070.0101328417542170506.2568_
19450____________ +1.16 +1.050.0410.0300.1761205913998126996.3089_putativetransmembraneprotein
*192208___________ +1.52 +1.280.0010.0030.0071958829852251226.3577_
194669___________ -1.07 -1.130.3090.3670.2422187920427193666.4067_aspartateaminotransferase
194374___________ +1.29 +1.220.0020.0050.0041665021456203486.4539_U1snRNA-associatedprotein;pre-mRNAsplicing
193327___________ +1.33 +1.260.0030.0060.0101277116996160496.5028_
*196304___________ +1.33 +1.360.0010.0030.0021721822847234816.5497_L-aminoadipate-semialdehydedehydrogenase
192035___________ +1.09 +1.050.0850.0470.3721483116191155366.5974_hypotheticalprotein
*191635___________ -2.30 -2.280.0000.0000.0008106003517623549756.6437_largesubunitribosomalproteinL12.e
*195654___________ -1.34 -1.260.0030.0050.01310196276037806856.6894_zincmetalloprotease|a-factorprecursorprocessing
196949___________ +1.18 +1.090.0140.0100.1301270614940138056.7335_hypotheticalprotein
*193043___________ -1.43 -1.500.0000.0000.0003972827778264426.7780_triglyceridelipase
*193231___________ +1.19 +1.170.0110.0130.0511398016665163786.8231_cellcycleprotein
*195424___________ +1.99 +2.260.0010.0030.0011578731393356976.8660_hypotheticalprotein
*195928___________ -2.46 -2.730.0000.0000.0006248322540172287426.9109_acidicribosomalproteinP2B|ribosomalproteinP2B(YP2beta)(L45)
*193100___________ +2.34 +2.180.0000.0010.0011813742432395036.149__
194404___________ +1.38 +1.260.0040.0070.0171467620187184386.657__
*191860___________ +1.08 +1.210.0280.0810.0343963442921478206.1260_
192168___________ -1.01 -1.010.6020.6190.4312688726507266146.1805_hypotheticalmembraneprotein
191647___________ +1.19 +1.110.0360.0320.1201842421962204346.2333_hypotheticalprotein
19928____________ +1.23 +1.150.0240.0450.0441475518098169136.2860_hypotheticalprotein
194649___________ +1.25 +1.210.0020.0040.0131865623391225376.3345_
*19832____________ +1.46 +1.350.0000.0020.0021726225215232186.3844_
*194473___________ +1.83 +1.830.0000.0020.0011636629880299466.4314_spindlepolecomponent
19284____________ -1.13 -1.020.1620.0810.5474029835609395496.4813_hypotheticalprotein
*193008___________ -1.89 -1.900.0000.0000.0009060448028477426.5281_biosynthesisofcoenzymeQ
193582___________ +1.13 +1.060.0300.0240.1441684019094178236.5747_conservedhypotheticalprotein
*196598___________ +1.19 +1.470.0040.0680.0035263062474771966.6211_
*194533___________ -1.27 -1.050.0080.0060.1363267225687311626.6679_ligatin|traffickingreceptorforphosphoglycoproteins
*191444___________ +1.15 +1.170.0140.0380.0243637241750424696.7129_epsinN-terminalhomology-containingprotein|clathrinbindingprotein,requiredforendocytosis
*196038___________ +1.25 +1.360.0030.0060.0131687821136230076.7582_putativetranscriptionalregulator
194988___________ +1.04 +1.070.0960.1640.0981293613490138286.8020_
*197091___________ -2.77 -2.550.0000.0000.0006367323009249476.8462_conservedhypotheticalprotein
*197550___________ +1.04 +1.130.0440.3950.0262145622399242186.8898_ORFMSV011leucinerichrepeatgenefamilyprotein
42889____________ +1.04 +1.080.1020.1360.1241234412790133104.2889_
19384____________ +1.05 +1.060.1270.0960.2571675617604177866.341__
194231___________ +1.26 +1.120.0040.0040.0401306216514146246.966__
*192818___________ +1.38 +1.290.0030.0070.0111561221616201796.1525_
*19377____________ -1.87 -1.540.0010.0020.0122005621071221298586.2069_glycophospholipid
*194869___________ +1.25 +1.200.0020.0060.0041953124390234136.2584_GATAtypetranscriptionalactivatorofnitrogen-regulatedgenes
191308___________ +1.22 +1.200.0060.0110.0191480618025178266.3105_
192607___________ -1.01 +1.040.7960.6240.7102830028075293596.3592_
191958___________ +1.09 +1.040.0470.0250.3891254113669130276.4081_hypotheticalprotein
*1952_____________ +1.19 +1.290.0030.0230.0043299439184424856.4554_mitochondrialproteinwithroleinironaccumulation
191964___________ +1.11 +1.090.0260.0260.0931293114332140716.5040_conservedhypotheticalprotein
196318___________ -1.32 -1.020.2870.1360.8098206862273802006.5511_conservedhypotheticalprotein
*192047___________ +1.74 +1.830.0000.0000.0002824149069516186.5986_conservedhypotheticalprotein
191619___________ +1.21 +1.150.0050.0070.0321629619665187846.6453_kinaseofRNApolymeraseIIcarboxy-terminaldomain(CTD),alphasubunit
*195666___________ +1.63 +1.730.0000.0020.0013302753882570776.6906_transcriptionalcoactivator
*194857___________ -1.47 -1.250.0000.0010.0074783232507382266.7354_hypotheticalprotein
193055___________ -1.14 +1.010.0130.0070.5282772624258279296.7792_subunitofRNApolymeraseIIholoenzyme
*193244___________ -1.95 -1.780.0000.0000.0013615818532202586.8244_conservedhypotheticalprotein
*195438___________ +1.33 +1.530.0000.0040.0011951025905298076.8674_hypotheticalprotein
*195912___________ +1.48 +1.850.0010.0040.0022010729728371626.9123_
*195057___________ +1.25 +1.190.0040.0060.0171788622355212346.16___
192723___________ +1.07 +1.100.1430.2700.1131307613939143586.678__
*191926___________ +1.46 +1.620.0030.0090.0071378020148222696.1277_putativetranscriptionfactor
61822____________ +1.15 +1.090.0300.0250.1321304614954141856.1822_
192539___________ +1.09 +1.020.2860.1700.5012072122661210666.2348_hypotheticalprotein
193699___________ +1.02 +1.020.2920.1440.7401253812850127986.2878_proteintyrosinephosphatase
196499___________ +1.17 +1.140.0130.0220.0331314115370149666.3364_DNA-directedRNApolymerase
192391___________ +1.23 +1.320.0030.0100.0061556219211204886.3857_conservedhypotheticalprotein
*193401___________ +1.16 +1.060.0280.0240.1193070835471326206.4330_involvedinvacuolarproteinsorting
19604____________ +1.16 +1.350.0110.0320.0201323415325178616.4827_phenol2-monooxygenase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
191362___________ +1.11 +1.080.1140.0550.5441360715091146966.5294_suppressorofmitochondrialmutationintRNA(asp)gene
193567___________ +1.04 +1.020.2830.1360.7631295413452131546.5763_
*196612___________ +1.32 +1.260.0090.0110.0392934038659370556.6224_electron-transferringflavoprotein,betachain
194545___________ +1.16 +1.080.0320.0250.1531367315904147976.6691_transcriptionfactorsimilartoSWI4
196879___________ +1.21 +1.110.0910.0430.5421692920466188296.7143_tRNAsplicingendonucleasesubunit
*196052___________ +1.01 -1.190.0340.6370.0186872869285577146.7596_putativeproteinphosphataseandproteinfoldingchaperone
*197136___________ +1.64 +1.660.0030.0060.0101603226296265966.8038_
197077___________ +1.09 +1.030.2980.1780.5071803519637185516.8476_transmembranesubunitofferricreductase
*197564___________ +1.25 +1.370.0030.0110.0061472118378201546.8912_DNA-directedDNApolymeraseepsilon,subunitB
43072____________ +1.14 +1.210.0170.0320.0341390815814167734.3072_
*194257___________ +3.69 +3.870.0000.0020.0011538456803595126.359__
196245___________ -1.02 -1.030.3160.4150.2292072220369201276.985__
*19852____________ +1.49 +1.480.0000.0010.0012510837335372206.1542_Gpi-anchoredasparticprotease
*194736___________ +2.92 +2.520.0000.0010.0011878854849474246.2087_vacuolaralcalinephosphatase
19130____________ +1.45 +1.550.0030.0060.0111386720146214256.2602_vacuolarproteinsortingproteinkinase
191706___________ +1.13 +1.100.0260.0220.1161267214366139276.3121_TFIIHregulator
192789___________ +1.29 +1.240.0060.0060.0391839623788228916.3606_
191753___________ +1.15 +1.130.0230.0290.0651257414482142476.4096_
*195689___________ -1.13 -1.270.0060.1240.0051289541137601019026.4567_sec28pepsilon-COPcoatomersubunit
195862___________ +1.33 +1.280.0040.0080.0131464319454187306.5054_arginase
196336___________ -1.05 -1.050.5390.7210.3364404241961420936.5528_
*196457___________ +1.35 +1.470.0040.0150.0081492020148219106.6002_conservedhypotheticalprotein
*193439___________ +1.92 +1.730.0000.0010.0032676051390462476.6466_hypotheticalprotein
193125___________ +1.08 +1.110.0610.1040.0772116122794233886.6920_conservedhypotheticalprotein
194842___________ +1.05 +1.010.3090.1620.6504449746710450946.7369_hypotheticalprotein
*196450___________ +1.66 +1.660.0010.0030.0031726028643287356.7804_hypotheticalprotein
*193256___________ +1.49 +1.350.0020.0040.0091724425634232766.8258_
*195450___________ -2.10 -2.630.0000.0010.000232286110546882066.8686_2-enoylthioesterreductase
195901___________ +1.28 +1.200.0080.0100.0381547019758186196.9137_
*194956___________ +2.39 +2.130.0020.0040.0061483135512315886.52___
*19767____________ +1.76 +1.860.0000.0000.0002772948928516816.696__
191989___________ -1.03 -1.070.2890.5550.1723845437238360046.1293_DefectiveCellWall
*194634___________ +1.22 +1.220.0050.0140.0132546230988309616.1840_conservedproteinoftheN-typeATPpyrophosphatasesuperfamily
*194643___________ +1.72 +1.570.0020.0050.0111425124534224226.2364_
192883___________ +1.19 +1.090.0130.0130.0751540418285168586.2895_conservedhypotheticalprotein
*195058___________ +1.55 +1.260.0050.0080.0231372921213173116.3378_regulatorof1,3-beta-glucansynthesis
193691___________ +1.00 +1.010.5220.2850.8852650926607266436.3875_conservedhypotheticalprotein
*192198___________ +1.58 +1.670.0030.0080.0071425922520238016.4343_conservedhypotheticalmembraneprotein
*191719___________ +1.12 +1.220.0040.0590.0042442527256298266.4841_glucoamylase
*193710___________ +1.31 +1.220.0040.0070.0192231829194271426.5308_flavohemoglobin|dihydropteridinereductase
196346___________ +1.07 +1.060.0430.0290.2001221113113128996.5775_similartoBRCA2andCip1/p21interactingprotein
*196100___________ +1.16 +1.150.0050.0090.0192164425079248516.6240_
19816____________ +1.20 +1.170.0160.0230.0431395416705163476.6708_
*196893___________ +1.40 +1.490.0020.0070.0061443820269215806.7158_
*196064___________ +1.15 +1.320.0150.1090.0145422462325713666.7608_involvedinautophagyandvacuolartargeting
*197153___________ +1.43 +1.690.0060.0230.0101633923385276256.8053_tRNAtransportreceptor
*197063___________ +1.36 +1.310.0020.0050.0073789251433494976.8490_conservedhypotheticalprotein
197578___________ -1.08 -1.070.0650.1450.0661955418051181986.8926_conservedhypotheticalprotein
PHR2_____________ +1.16 +1.060.0470.0260.325143321656815196PHR2___
*195565___________ -2.33 -2.490.0020.0060.0064081617546164016.377__