ΔMEP2 low ammonium

03-Feb-2014 by fellenb
multiconditional experiment no. (if not recombined):
measurement selection: {{428,429,432,433,436,437,438,439},{442,443,452,453,0,0,0,0},{446,447,450,451,0,0,0,0}}
multi-channel data:
+control (i.e. reference) at 428 429 432 433 436 437 438 439 428 429 438 439 432 433 436 437
local background: subtracted
normalization: log. reg. 2
filtering:
+filter 1: 2 1 29000 3
+on conditions: 1 1 1
+filter 2: 7 0 0.05 2
+on conditions: 0 1 1
+filter 3: 0 1 NaN 3
+on conditions: 0 1 1
correspondence analysis:
+feeding: log of flatprim, flatsecu
+hybs: mass to median of each condition only
+genes: restricted by geneorder (you picked 3087)
selection (asterisk in first column): represents filtering
intensity threshold for pvalue-based color code: 29000


factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
1938_____________ +1.05 +1.050.1830.1050.4471305813655137086.2____hypotheticalprotein
*193467___________ +1.59 +1.640.0030.0070.0111354721500222066.498__RNasePa
*195741___________ +8.31 +9.890.0000.0000.000283912359522808096.1116_conserv
*19775____________ +1.22 +1.150.0280.0400.0622352028696271466.1671_vacuolartargetingprotein
*192820___________ +1.74 +1.830.0010.0040.0041845532174337906.2208_hypothe
*192709___________ +3.24 +3.810.0000.0010.0002063466755787036.2725_zuotin,aputativeZ-DNAbindingprotein
*191730___________ +1.30 +1.190.0060.0070.0442840836958338756.3234_non-histoneprotein10
192797___________ +1.06 +1.110.0370.0730.0521398814825154706.3726_putativehelicase
*192344___________ -13.65 -12.340.0000.0000.00041191430172333686.4207_DNA-dir
*192736___________ +2.24 +1.920.0000.0020.0012489555778477316.4692_transcriptionalregulator,partofNC2complex
*192423___________ +1.39 +1.390.0020.0050.0082250831362312966.5169_ureaact
*19314____________ +1.32 +1.020.0390.0190.4623073140573313126.5644_partofproteincomplexwithSin3pandStb1p
193423___________ +1.06 +1.070.0400.0370.1221382214587148016.6101_ORFMSV0
*19679____________ -1.20 -1.200.0110.0270.0232718822686226656.6572_hypotheticalprotein
*191901___________ +1.72 +1.430.0010.0010.0043740464428534096.7019_memberofcomplexthatactsatARS'stoinitiatereplication
*192081___________ +1.70 +1.480.0000.0010.0034209571734624536.7474_nuclearporemembraneglycoprotein
194620___________ -1.37 -1.490.0010.0060.0032424417659163126.7919_subunitoftheTIM22-complexinvolvedinmitochondrialbiogenesis
*197283___________ -2.55 -3.370.0000.0010.00015127259296449536.8364_hypotheticalprotein
*196833___________ +1.64 +1.880.0020.0090.0051398022911262826.8798_bumetanide-sensitiveNa-K-Clcotransportprotein,5-primeend
Caaf1____________ +1.11 +1.020.1660.0850.531119181317612203Caaf1__isoamyl
*195619___________ +1.38 +1.230.0000.0000.0042309431954283066.213__zincfin
*191649___________ +2.92 +3.200.0000.0010.0012131662194682966.825__alpha-g
*192519___________ +1.56 +1.460.0000.0010.0011770227651258046.1400_nuclearenvelopeprotein
193510___________ +1.08 +1.030.3230.2130.4581280913825132366.1943_hypotheticalgene
*193608___________ +1.55 +1.490.0010.0020.0021806627939269496.2464_actsinDNAmismatchrepair
*19796____________ +1.52 +1.400.0000.0010.0031728126252241146.2996_
*19139____________ +1.74 +1.490.0020.0060.0081730830076257076.3475_histoneacetyltransferase,componentoftheNuA4transcriptionalregulatorycomplex
*194257___________ +2.04 +1.670.0010.0010.0031763735914294336.3968_
19304____________ +1.21 +1.200.0070.0120.0241286715546153886.4441_
*191054___________ +1.96 +1.960.0000.0020.0011670032696328106.4935_
*196179___________ -2.29 -2.480.0020.0050.0053969417319160216.5400_hypotheticalprotein
193140___________ +1.11 +1.140.0190.0360.0391266614060144186.5877_
*195110___________ +2.29 +2.710.0000.0010.0012192350308594536.6339_
*196692___________ +3.34 +3.360.0000.0000.0002224774301746406.6801_alpha-1,2-mannosyltransferase
19359____________ -1.11 -1.140.0100.0510.0122027818239178346.7243_glutathioneS-transferase
195249___________ +1.29 +1.240.0010.0030.0051800223224223436.7693_conservedhypotheticalprotein
*197239___________ +1.46 +1.360.0010.0020.0021747225443237786.8139_regulationofG-proteinfunction
197411___________ +1.21 +1.260.0040.0160.0071583619213200256.8571_mitochondrialoxaloacetatetransportprotein
*197670___________ +2.21 +2.440.0000.0010.0011691037371411856.9017_
626______________ +1.30 +1.180.0060.0070.0491273116566150526.26___
*19231____________ +1.51 +1.340.0010.0020.0042223433538297036.518__
*19798____________ +1.35 +1.260.0000.0010.0022689836352339356.1138_transcriptioninitiationfactorTFIIFsmallsubunit|requiredforactincytoskeletonassemblyorfunction
193728___________ +1.19 +1.250.0180.0220.0561256615007156576.1687_
*193603___________ +1.50 +1.550.0010.0030.0032346335297364556.2224_conservedhypotheticalprotein
62744____________ +1.10 +1.080.0310.0300.1021247413673134496.2744_
*195561___________ +1.50 +1.520.0010.0020.0021758826352267446.3250_proteaseinvolvedina-factorprocessing
*193077___________ +1.38 +1.520.0020.0090.0033741451548567236.3742_
*194415___________ +1.26 +1.280.0010.0030.0032630633241337646.4224_
194654___________ +1.07 +1.070.0650.0490.2001266813569135996.4705_hypotheticalprotein
*192408___________ +1.23 +1.270.0020.0070.0051825222500231156.5185_conservedhypotheticalprotein
193981___________ +1.07 +1.050.5070.3130.6541423915190150176.5657_maltosepermease
192906___________ -1.01 +1.010.9440.8460.8182503824888252606.6116_hypotheticalprotein
*192765___________ +2.38 +2.730.0000.0010.0012215452807604346.6588_
191888___________ +1.12 +1.110.0110.0140.0491593217808176736.7032_uridineribohydrolase
*192069___________ +1.47 +1.480.0000.0010.0011921428173284756.7486_vacuolarmetaltransporter
*197006___________ +1.23 +1.260.0030.0060.0131611419837203336.7932_hypotheticalprotein
*197296___________ +2.29 +2.730.0000.0010.0002130348755581456.8377_conservedhypotheticalprotein
*196818___________ -1.23 -1.140.0050.0070.0242978024237262376.8813_RNAhelicase
Cacre9___________ -1.01 +1.020.6140.3530.960150121488715365Cacre9_
*196951___________ +1.77 +1.960.0000.0000.0002226239506435746.232__
*191534___________ +1.49 +1.510.0000.0010.0002255033687340716.838__
195753___________ +1.53 +1.410.0010.0020.0021643625147231716.1416_sugartransporter
*191917___________ +1.50 +1.700.0000.0010.0002512137658428286.1960_
191980___________ +1.18 +1.150.0090.0140.0291651419454189326.2480_glycerophosphoinositolpermease
*191250___________ +1.42 +1.350.0010.0030.0041837726048248096.3009_conservedhypotheticalprotein
*194268___________ +1.60 +1.800.0000.0020.0011986031844357336.3489_conservedhypotheticalprotein
*194774___________ -1.12 -1.020.0470.0240.4272853425591278616.3985_alternativeoxidase
*195515___________ -1.73 -1.840.0000.0010.0014216524361229666.4457_involvedincytochrome-creductaseassembly
195849___________ -1.08 -1.040.4360.2290.8203266830166313756.4951_transcriptionalregulator
196209___________ +1.09 +1.080.1070.1190.1512082622780225906.5414_
192253___________ +1.20 +1.090.1090.0470.8021521718212166346.5891_
192005___________ +1.03 +1.010.5070.2760.8581494415406151226.6356_
*196706___________ +1.91 +2.090.0000.0000.0002682451124560946.6815_GTPaseactivatingprotein
*194445___________ +1.55 -1.370.0010.0030.0092046031673148846.7258_hypotheticalprotein
195236___________ -1.23 -1.140.0090.0110.0482479820211217616.7706_cis-prenyltransferasehomologue
197254___________ +1.11 +1.100.0350.0410.0861802219989197966.8153_
197426___________ -1.16 -1.100.0360.0390.0952543621853230466.8586_subunitofN-oligosaccharyltransferasecomplex
*69033____________ +1.47 +1.710.0000.0010.0021604923590273836.9033_
193748___________ +1.21 +1.200.0120.0220.0301260515309151156.47___
191813___________ +1.28 +1.170.0060.0080.0311257816116146646.539__
*1917891__________ +1.69 +1.570.0010.0020.0021634527588255996.1158_NA
1910_____________ -1.08 -1.120.0170.0510.0241918017720171156.1706_cytochromep450
*193350___________ -1.42 -1.670.0050.0250.0084687033014281436.2238_mitochondrialribosomalprotein
192355___________ +1.10 +1.060.0810.0730.1691328414569140586.2760_
*192862___________ +1.24 +1.220.0120.0150.0482268828160276546.3269_
*194910___________ +1.50 +1.380.0010.0010.0106011790261829146.3757_hypotheticalprotein
*191287___________ +3.72 +3.370.0000.0000.000424181576871430086.4238_hypotheticalprotein
*19570____________ +1.76 +1.580.0000.0010.0012305340655364726.4721_
194287___________ -1.06 -1.060.1530.0950.3641697216050160816.5199_
196142___________ +1.08 +1.070.0570.0400.2131273213717136686.5672_conservedhypotheticalprotein
*192893___________ +1.57 +1.470.0010.0020.0023211150261471136.6129_partofmRNAspliceosomecomplex
194244___________ +1.17 +1.130.0040.0060.0181744320325196926.6601_
*191874___________ +1.33 +1.220.0030.0050.0151846524582224396.7046_serine/threonineproteinkinase
*192055___________ +1.67 +1.380.0000.0010.0012575842954354196.7499_
*197020___________ +1.29 +1.180.0040.0050.0284201654216497776.7946_carboxypeptidaseB-likeprocessingprotease|Killertoxinandalphafactorprecursorprocessing
*197310___________ -2.48 -2.350.0000.0000.00014506458509618186.8390_
*196805___________ -1.93 -2.110.0000.0000.0004397222749208126.8826_conservedhypotheticalprotein
42967____________ -1.01 +1.000.9210.9900.7201180811745118664.2967_
19384____________ +1.23 +1.070.0130.0100.1251615619805172396.247__
*193187___________ +1.50 +1.380.0000.0010.0023847257532531366.853__

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*192632___________ +1.84 +1.810.0000.0010.0012888153095523346.1437_RNAhelicaserequiredfor60Sribosomalsubunitassembly
*191950___________ -1.42 -1.460.0000.0020.0015342637629366206.1976_putativehydrolase
*193685___________ +2.39 +2.830.0010.0030.0021567237418442836.2494_
193226___________ +1.29 +1.170.0020.0030.0121317617047154756.3025_vacuolarproteinandhomologofNiemannPicktypeCprotein
195192___________ +1.29 +1.320.0030.0090.0071314616956173646.3503_conservedhypotheticalprotein
192938___________ -1.08 -1.120.3870.3430.3613822035469342596.4002_conservedhypotheticalprotein
*195530___________ +1.98 +2.010.0010.0020.0021711733891344106.4471_
192469___________ +1.01 +1.000.8750.6340.9602215622409221936.4966_ssDNAendonucleaseandrepairprotein
*196195___________ +1.72 +1.720.0000.0010.0002888249795495836.5429_ribonucleaseH
194927___________ +1.24 +1.260.0060.0100.0221487718510187126.5906_
196614___________ +1.06 -1.030.3940.2890.4442236223614216456.6375_
194105___________ +1.17 +1.240.0020.0080.0061838221587227396.6831_conservedhypotheticalprotein
*19906____________ +1.35 +1.280.0010.0030.0043194143268410316.7271_GDP-GTPexchangeproteinforRho1
196975___________ +1.09 +1.080.2660.3040.2301087541184351178856.7720_
*197269___________ -1.48 -1.770.0000.0030.0017828452777443326.8168_
197440___________ +1.10 +1.120.0120.0340.0201436815791160946.8600_ATP-dependentpermease
*195989___________ -1.76 -1.580.0000.0010.00210304858573651566.9047_
19376____________ +1.11 +1.020.0950.0520.3951548417122158356.64___
*192400___________ +1.49 +1.370.0030.0060.0131365620305187486.560__
19144____________ +1.22 +1.130.0070.0100.0311297115866147146.1176_ATPdependentRNAhelicaseandU5mRNAsplicingfactor
195576___________ +1.00 -1.010.6750.8850.4271743717473172646.1723_
62257____________ +1.21 +1.140.0090.0120.0371246815089142506.2257_
*191304___________ +1.44 +1.380.0030.0070.0111521421925210106.2776_rRNAprocessingexoribonucleasecomplexcomponent
*193612___________ -2.41 -2.170.0000.0000.00011982149693552866.3282_NADH:quinoneoxidoreductase|1,4-benzoquinonereductase
194366___________ +1.15 +1.090.0230.0200.1131277014652139046.3772_
*191835___________ +1.61 +1.630.0000.0010.0011650626538269366.4251_requiredforsomeformsofpolarizedgrowth,localizedtositesofpolarizedgrowth
*193347___________ -1.27 -1.250.0040.0110.0113687128959294766.4738_RNApolymeraseIIsubunit
194807___________ +1.11 +1.040.0980.0550.3691331214754138566.5213_mitochondrialinorganicpyrophosphatase
19593____________ +1.11 +1.080.0300.0320.0921231313613133086.5684_
195835___________ +1.09 +1.130.0290.0580.0441831220052206726.6142_
*194229___________ -1.61 -1.620.0010.0030.0043114519307191696.6616_polyphosphatephosphohydrolase
*19508____________ +2.98 +2.510.0000.0010.0021250937285314416.7063_multidrugresistancetransporter
193819___________ +1.13 +1.090.0130.0130.0681421316098155246.7514_hypotheticalprotein
*197033___________ +3.60 +3.090.0000.0000.0001700561256524716.7959_proteintyrosinephosphatase
*197322___________ +1.05 +1.290.0110.9800.00684806892521096926.8403_conservedhypotheticalprotein
196792___________ +1.18 +1.210.1390.3320.0961433216970173776.8839_ResistanttoRapamycinDeletion
41743____________ -1.02 -1.020.4570.2740.6401292712694126574.1743_
*1976_____________ +1.52 +1.580.0020.0080.0041550223621245086.268__
191279___________ -1.01 -1.020.6880.4160.9772771827402270816.874__CDP-diacylglycerolsynthase
*19258____________ +11.04 +14.570.0000.0000.000145301603402117456.1453_hypotheticalprotein
6199_____________ +1.19 +1.110.0070.0080.0431309315611145856.1990_
19107____________ +1.14 +1.130.0130.0140.0571282414596144406.2511_
191700___________ +1.07 +1.020.6140.3530.9621771918914180576.3041_ribosomalproteinS7A
*194703___________ +1.56 +1.430.0010.0030.0051693426453241856.3518_similartoricefar-redimpairedresponseprotein-like
*194744___________ +1.30 +1.230.0030.0040.0181331917266164206.4015_
*193190___________ +1.05 +1.160.0170.1520.0142817629702327386.4487_3rdgeneinHAL9repeatunit;weaksimtoHAL9factorinvolvedinsalttolerance;potentialFungalZn2Cys6Clusterdomain
193480___________ +1.00 -1.050.5590.7140.3561764317713167316.4979_ATPase(putative)|mitochondrialribosomesmallsubunitcomponent
196295___________ +1.02 -1.020.9130.6940.9861628916656160346.5445_subunitofthemitochondrialprocessingprotease
1928_____________ +1.04 +1.060.1030.0720.2601505115669158976.5922_mitochondrialthiaminepyrophosphatetransporter
191420___________ +1.04 +1.090.0820.3030.0551807318821196586.6389_conservedhypotheticalprotein
194091___________ +1.04 +1.050.1400.1800.1501646017071172336.6845_subunitofRNApolymeraseIIholoenzyme/mediatorcomplex
19893____________ +1.10 +1.020.0580.0250.7581297114226132626.7285_
196986___________ +1.08 +1.050.0940.0490.4351469015925153756.7732_putativeGTPaseactivatingprotein
192224___________ +1.07 +1.030.3150.2150.4331697618235174466.8183_
197452___________ +1.06 +1.100.0470.0650.0801464615571160666.8612_involvedinDNAreplication
195976___________ +1.20 +1.120.3460.1700.8411451517374162256.9061_hypotheticalprotein
69_______________ +1.29 +1.190.0130.0160.0511229915912146326.90___
19981____________ +1.17 +1.110.0130.0130.0751603218829177506.580__hypotheticalprotein
191818___________ +1.29 +1.290.0030.0060.0101265516360162696.1195_
*19449____________ +2.27 +2.070.0020.0040.0111504434138311566.1739_predictedphosphatidylsynthase
*196257___________ +2.89 +2.370.0000.0000.00038627111799916886.2273_
*194339___________ +1.51 +1.400.0020.0030.0081477422328207566.2796_vacuolarsortingprotein
194917___________ +1.39 +1.290.0030.0060.0141338118637172056.3296_hypotheticalprotein
195728___________ +1.23 +1.160.0050.0080.0251389417113160746.3792_
*192220___________ +33.15 +24.770.0000.0000.000261248660216472076.4265_hypotheticalprotein
*192107___________ +1.54 +1.200.0010.0010.0285190680078624706.4754_cholinephosphatecytidylyltransferase|phosphoethanolaminecytidylyltransferase
65228____________ +1.08 +1.080.0640.0560.1601258213579135286.5228_
192987___________ +1.02 -1.010.8980.7570.7792118421687209806.5702_hypotheticalmembraneprotein
*195823___________ -1.30 -1.470.0000.0010.0005311840951361136.6155_smallglutamine-richtetratricopeptiderepeatcontainingprotein|similaritytoproteinphosphatases
*195798___________ +1.14 +1.120.0140.0310.0282511428540282246.6632_DNAligaseIV
*19492____________ -1.06 -1.200.0390.3300.0259528890130793916.7079_5-aminoimidazole-4-carboxamideribonucleotide(AICAR)transformylase
*193836___________ +1.27 +1.190.0180.0120.1621781422698212296.7532_
*197047___________ +1.38 +1.370.0030.0070.0082528734875346246.7973_regulatesDNAbindingpropertiesofTATA-bindingprotein
197335___________ +1.17 +1.120.1150.2030.1063390639643380656.8416_20SproteasomesubunitY7
196780___________ +1.08 +1.070.0860.0840.1551436415449153576.8851_expressionofPAPSreductaseandsulfitereductase
42227____________ +1.01 +1.030.3500.2750.3851180711938121154.2227_
194512___________ +1.34 +1.260.0030.0050.0101276717136160806.281__
*193728___________ +1.48 +1.480.0060.0070.0311674124727247676.895__
192661___________ +1.31 +1.190.0010.0030.0081326617327158326.1466_transcriptionfactor
*191681___________ +3.20 +2.870.0000.0000.0002924993732839566.2003_
*191782___________ -1.41 -1.470.0000.0020.0015776540956394206.2529_conservedhypotheticalprotein
*194795___________ +2.99 +3.020.0010.0020.0021359240697410136.3054_
*19649____________ +1.65 +1.510.0020.0050.0091382022828208976.3532_
195097___________ +1.40 +1.410.0030.0070.0091433020083201486.4031_
*192838___________ +1.61 +1.850.0000.0000.0003556757124656266.4499_putativebeta-mannosidase
*194519___________ +1.10 +1.210.0150.2370.0113440437758416666.4992_mitochondrialRNAhelicase
*194678___________ +1.13 +1.080.0340.0270.1473194635990345916.5458_triacylglycerollipaseprecursor
*19204____________ +1.53 +1.420.0010.0020.0041570424066223126.5936_hypotheticalprotein
*191545___________ -1.46 -1.510.0000.0000.0004252229111282066.6403_mitochondrialribosomeprotein,smallsubunit
194079___________ +1.18 +1.180.0100.0230.0201672819765196906.6857_potentialSPFHdomain|possibleregulatorofcationconductance
673______________ +1.05 +1.060.0840.1030.1221197212539126816.7300_
196998___________ +1.22 +1.170.0080.0110.0291291415795151066.7744_glutathioneS-transferase
*19946____________ -2.10 -1.750.0000.0000.0008105738641463296.8195_adenylylsulfatekinase
*195389___________ +1.94 +1.930.0010.0030.0021532429804295866.8625_transcriptionfactor
195964___________ +1.08 +1.040.0910.0570.2991429415468148826.9073_ADP-ribosylationfactor|GTP-bindingprotein
*192479___________ +1.95 +1.620.0010.0030.0061287825065208086.108__
*19245____________ +1.33 +1.280.0020.0050.0091591521202203576.602__
192024___________ +1.34 +1.260.0040.0060.0161239316567156106.1212_
196079___________ +1.23 +1.100.0100.0090.0861291015903142416.1757_
*193772___________ -1.27 -1.190.0040.0060.0184335634005363916.2289_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*197561___________ +1.77 +1.950.0000.0010.0003141955672612116.2818_
*193651___________ -2.21 -1.900.0000.0000.0002546271153571338846.3309_
192557___________ +1.18 +1.120.0050.0070.0281481017494166306.3805_
193533___________ -1.03 -1.030.6910.6390.5251355913171131026.4279_
192371___________ +1.32 +1.810.2350.6410.1262988439409539516.4769_retrotransposongagprotein
193858___________ +1.25 +1.160.0060.0100.0211394717469162006.5247_
*192973___________ +1.34 +1.470.0010.0040.0012938639289432586.5716_conservedhypotheticalprotein
192488___________ +1.27 +1.250.0050.0160.0101508819227187956.6169_RNAhelicaseinvolvedinmaturationof18SrRNA
*195813___________ +2.32 +2.660.0000.0000.000475351102851265266.6647_
19477____________ -1.01 -1.050.5170.8420.2991615216009153996.7093_
*196559___________ +1.30 +1.360.0020.0070.0061609620880218866.7547_putativetranscriptioninitiationfactor
195023___________ +1.07 +1.120.0970.2740.0701250413428140356.7986_allantoatepermease
*197124___________ -1.67 -1.500.0020.0040.0081745101042941162656.8429_cytoskeletonstructure,endocytosis,cellfusionprotein
196766___________ +1.08 +1.110.0960.1510.1041413815294157016.8865_NucleolarProtein13
42533____________ +1.04 +1.050.6090.5050.5171442414950151224.2533_
192879___________ +1.28 +1.190.0090.0110.0391234615771147146.297__
*191296___________ +1.31 +1.310.0010.0030.0031609521140211426.922__pre-mRNAsplicingprotein
194954___________ +1.13 +1.070.0440.0330.1732163624526230676.1487_vacuolarATPaseV0domainsubunitc
194901___________ +1.25 +1.230.0030.0060.0101384017261170056.2024_trans-aconitatemethyltransferase
19806____________ +1.17 +1.140.0100.0150.0371987223154226456.2545_vacuolarH(+)-ATPase(subunitF)
193795___________ +1.22 +1.150.0040.0060.0231352616568155336.3068_aminoacidpermease
*19861____________ +1.48 +1.380.0000.0010.0022187132276301456.3553_bZIPprotein|transcriptionfactor
195813___________ -1.04 -1.080.1720.6570.0891189011462109746.4046_conservedhypotheticalprotein
*195645___________ -2.53 -2.190.0000.0000.00012466449337568836.4514_O-acetylhomoserinesulfhydrylase
*194215___________ +6.07 +6.410.0000.0000.000194931183451248746.5006_multicopperferro-O2-oxidoreductaseinvolvedinhigh-affinityironuptake
65471____________ +1.07 +1.070.0540.0390.1941223813144130416.5471_
195145___________ +1.13 +1.080.0340.0210.2291298214719139616.5953_
191560___________ -1.09 -1.080.1090.1200.1532060418819190596.6417_DNApolymerasedeltabindingprotein
196723___________ -1.19 -1.090.0100.0080.1162594521852237296.6872_hypotheticalprotein
*196927___________ +1.33 +1.440.0000.0010.0012583834412372766.7313_vesiculartransport
*193022___________ -1.88 -1.960.0010.0020.0023563818984181656.7759_mitochondrialribosomesmallsubunitcomponent
*19956____________ +1.93 +2.060.0000.0010.0011574830463324906.8210_
195404___________ +1.12 +1.110.0190.0220.0661442416192160796.8639_
195949___________ +1.10 +1.040.0990.0440.6781220013390127206.9087_
19141____________ +1.17 +1.170.0040.0080.0181230414423144066.127__hypotheticalprotein
6626_____________ +1.15 +1.160.0160.0350.0301276814640148166.626__
*192708___________ +1.64 +1.500.0010.0020.0032928548067437946.1233_highlyconservedhypotheticalprotein,involvedin35SrRNAprocessing
*192841___________ +2.05 +1.950.0020.0060.0061555831888303056.1775_phosphoglucomutase
*191538___________ +1.42 +1.370.0030.0060.0101444520464197416.2307_memberofthesyntaxinfamilyoft-SNAREs
194969___________ +1.14 +1.090.0090.0100.0461401215912153376.2837_
*19700____________ +1.69 +1.520.0000.0010.0013481458826530176.3324_
192642___________ -1.07 -1.080.0680.3260.0441176211014108676.3821_calmodulin
19301____________ +1.32 +1.180.0030.0060.0081603221138189716.4292_hypotheticalprotein,likelycellwalllocalizedandGPI-anchored
*195627___________ +1.58 +1.430.0000.0010.002845081331411205776.4786_simtornabindingprotein-putativepremrnasplicingfactor
*196552___________ +1.30 +1.210.0040.0050.0382487432451301836.5262_EssentialforRespirationandVegetativegrowth
*191261___________ +1.36 +1.170.0030.0040.0192185729725255776.5729_
195772___________ +1.25 +1.240.0070.0150.0181732221649214526.6186_actinoverexpressionresistant
*192956___________ -1.46 -1.660.0010.0030.0024510330958272136.6660_mitochondrialgenomemaintenanceprotein
191465___________ +1.27 +1.230.0030.0080.0091694421551208606.7108_arylalkylaminen-acetyltransferase
196575___________ +1.10 +1.080.1930.1390.3251550817128167216.7563_hypotheticalprotein
*195010___________ +1.57 +1.860.0010.0050.0031538224157286056.7999_dimethyladenosinetransferase
*197110___________ +1.40 +1.380.0010.0020.0022435534127336856.8443_tRNA-specificadenosinedeaminase
*196753___________ +1.24 +1.110.0150.0120.1143283840626363896.8878_conservedhypotheticalprotein
42762____________ +1.04 +1.040.1930.1440.3121227512804128184.2762_
*193599___________ +2.45 +2.350.0000.0010.0012225454528522736.316__
*19157____________ +1.23 +1.250.0130.0240.0304073350186508236.937__hypotheticalprotein
*193527___________ -6.88 -7.360.0000.0000.00067313397780914086.1503_
*193527___________ -9.18 -9.650.0000.0000.00016914001841531753196.2040_cytochromec1
*193787___________ +1.54 +1.510.0020.0040.0071760727135266106.2557_
*191214___________ +1.08 +1.210.0160.1490.0134336546842524356.3083_methionineaminopeptidase,isoform2
*192272___________ +1.62 +1.640.0020.0060.0061535824877251676.3570_
*193916___________ +1.69 +1.700.0010.0020.0021489225134252506.4060_hypotheticalprotein
196220___________ +1.33 +1.230.0040.0060.0181525620349187576.4532_conservedhypotheticalprotein
194200___________ +1.23 +1.100.0080.0080.0561477618161163196.5021_
192698___________ +1.09 +1.020.1230.0580.5841971321569200256.5486_conservedhypotheticalprotein
195132___________ +1.26 +1.190.0040.0070.0151429617970170126.5966_peroxisomalmembraneprotein
*191642___________ +1.31 +1.360.0030.0150.0061995226147271536.6430_nuclearmRNAbindingprotein
*196737___________ +1.12 +1.170.0160.0400.0273392238109397276.6886_hypotheticalprotein
*196941___________ -2.00 -2.340.0020.0100.004213620106830912466.7327_DiacylGlycerolAcyltransferase
*193035___________ +2.52 +2.530.0000.0010.0011919848319485566.7773_
*68224____________ +1.47 +1.510.0010.0030.0031701025054256056.8224_
*195418___________ -1.83 -1.790.0000.0000.0008220844802459786.8654_conservedhypotheticalprotein
195934___________ -1.27 -1.170.0040.0100.01211546910498606.9103_DNAtopoisomeraseIII
*192451___________ +1.12 +1.160.0250.0400.0511891121171219396.143__
*19999____________ -2.68 -2.920.0000.0000.0006845325561234316.649__glucoamylase
*192825___________ +1.23 +1.440.0010.0100.0013503843246504486.1251_
*19682____________ +1.37 +2.140.0000.0090.0002728037360584706.1794_
*192501___________ +1.65 +1.350.0020.0030.0101414623282190886.2325_
*191196___________ +1.53 +1.640.0000.0020.0012188433463358846.2850_
*193332___________ -1.68 -1.390.0000.0000.0027851246852564366.3339_hypotheticalprotein
*194878___________ +1.33 +1.380.0020.0090.0032798737195386316.3836_
*194479___________ +1.82 +2.000.0000.0030.0012616347524522656.4308_conservedhypotheticalprotein
*19276____________ +1.22 +1.280.0010.0060.0012653832360339936.4805_hypotheticalprotein
196539___________ -1.02 +1.010.6190.4290.6455281851563535376.5275_transcriptionalregulator
*191666___________ +1.57 +1.660.0000.0020.0011621025530268696.5741_hypotheticalprotein
*196591___________ +1.61 +1.770.0000.0010.0012081333536368816.6203_peroxisomalnudixhydrolaseactivetowardscoenzymeAanditsderivatives
*194527___________ +3.96 +2.640.0000.0000.001387681536321024446.6673_
191450___________ +1.03 +1.020.4570.2700.6591180212131120536.7123_hypotheticalprotein
*196588___________ +2.36 +2.620.0000.0000.0002685463300703856.7576_interactswithNap1,whichisinvolvedinhistoneassembly
194995___________ +1.01 +1.050.5900.4500.5501408714280148386.8014_hypotheticalprotein
197097___________ -1.05 +1.070.3120.3650.2476492262109696236.8456_RNAbindingprotein
*196739___________ +1.38 +1.700.0000.0020.0002224830699378316.8892_conservedhypotheticalproteinsimilartophosphomannomutases
42848f++3b_______ -1.05 -1.030.5210.6820.3291197611445116774.2848f
191356___________ +1.26 +1.180.0020.0030.0091510918984178656.331__
19236____________ +1.11 +1.090.0320.0370.0841967721811213636.955__ribosomalproteinL9B
191085___________ +1.18 +1.120.0100.0120.0521487617481166256.1518_
*19366____________ +1.22 +1.380.0010.0100.0024411053890607926.2056_3'-5'exonuclease
*193366___________ +1.02 +1.180.0160.3530.0101171541200031387306.2577_
*194565___________ -1.79 -1.380.0070.0070.07611939166867867836.3096_
192753___________ +1.10 +1.010.7310.4630.9262461027016248386.3585_hypotheticalprotein,zincfinger

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*192365___________ +1.53 +1.500.0000.0010.0021585724321238086.4075_DNA-directedDNApolymeraseepsilon,catalyticsubunitA
*1959_____________ +1.10 +1.370.0060.1350.0042970832611407976.4547_zincfingerproteinwithunknownfunction
*191970___________ +1.09 +1.160.0080.0400.0103175334544367126.5034_complementsS.cerevisiaevacuolebiogenesismutant,unpublished
*196312___________ -2.16 -1.880.0000.0000.000189344875451006666.5505_ribosomalproteinS3(rp13)(YS3)
*192041___________ -1.14 -1.110.0470.0340.1892977126096267806.5980_remodelsthestructureofchromatin
*191628___________ +1.20 +1.410.0000.0050.0003564042867502906.6445_
*195660___________ -1.95 -1.740.0000.0000.0004547923329261936.6900_peroxisomalbiogenesisprotein
196957___________ +1.14 +1.100.0120.0120.0671337815201146676.7343_hypotheticalprotein
193049___________ +1.03 -1.020.2870.1510.6311483815318146046.7786_putativeserine/threonineproteinkinase
193238___________ +1.06 +1.040.4000.2760.4851235313105128976.8238_hypotheticalprotein
*195431___________ +1.49 +2.080.0000.0010.0002008529946417446.8667_hypotheticalprotein
195920___________ -1.05 -1.010.2780.1270.9432278121746225816.9117_hypotheticalprotein
*191606___________ +1.78 +1.940.0030.0150.0051447725727281256.1____
*191217___________ +1.24 +1.150.0040.0060.0282364029306272326.669__conservedhypotheticalprotein
191907___________ +1.02 -1.040.5860.3430.8233253233299314296.1268_
193453___________ -1.10 -1.100.0440.1350.0431190810843108406.1813_
*193898___________ +1.61 +1.430.0010.0020.0052047032923292486.2341_memberofthesyntaxinfamilyoft-SNAREs
*19921____________ +1.88 +1.700.0000.0000.0013195459994544806.2867_hypotheticalprotein
192649___________ +1.20 +1.180.0080.0170.0191343716150157926.3355_
*19840____________ -1.53 -2.190.0000.0000.0003106112031851418496.3851_ribosomalproteinL21
193409___________ +1.28 +1.200.0050.0090.0181949525030233096.4322_
*19290____________ +1.71 +1.890.0020.0040.0051899132528358426.4818_
193001___________ +1.32 +1.230.0030.0060.0141612621226197716.5288_GTP-bindingproteinoftheRASsuperfamily
193574___________ +1.06 +1.050.1710.0870.5441238113174130256.5755_mitochondrialchaperoninoftheDnaJfamily
196605___________ +1.10 -1.080.2660.1240.8252691529477249926.6217_membraneproteinsimilartohumanandmouseglomerulosclerosisproteinMpv17
*194539___________ +2.41 +1.920.0000.0000.0003087574414593506.6685_putativerhoGDPdissociationinhibitor
196872___________ +1.18 +1.110.0070.0100.0311848221756204796.7136_similartoanthranilatesynthasecomponentII
*196045___________ -1.02 -1.340.0090.9810.0058951687822665966.7589_phosphatidylserinedecarboxylase
197130___________ -1.12 -1.210.0010.0290.0012141919197176786.8030_hypotheticalprotein
197083___________ +1.04 +1.060.1370.1020.2661570616354165746.8470_DefectiveinsisterChromatidCohesion|partofanalternativeRFCcomplex
197556___________ +1.05 +1.020.7620.5140.8372136722446218906.8904_hypotheticalprotein
43044____________ -1.02 -1.030.4670.9080.2561189411710115414.3044_
191086___________ +1.14 +1.120.0140.0220.0361280514552143296.349__
197451___________ +1.30 +1.170.0040.0060.0261275416567149636.974__
193820___________ -1.03 +1.050.4400.7700.2491184011508124306.1534_
*191386___________ +2.07 +1.820.0000.0010.0012188745332398326.2078_typeIImembraneproteinrequiredforvesiculartransportbetweentheendoplasmicreticulumandGolgicomplex|v-SNAREwithsimilaritytosynaptobrevins
*193775___________ +1.34 +1.200.0010.0020.0087340298054880916.2594_MAPkinasekinasekinase|ActivatorofPbs2p
191712___________ +1.20 +1.130.0140.0140.0741226814720138456.3115_
192783___________ +1.11 +1.120.0350.0490.0701436815923160246.3600_memberofthePir1p/Pir2p/Pir3pfamily
*191761___________ +1.25 +1.190.0030.0070.0102048425528243236.4088_oligosaccharyltransferaseepsilonsubunit
*195682___________ -1.19 -1.260.0060.0340.0091652301383701309176.4560_karyopherin-alphaorimportin
*195856___________ +1.49 +1.300.0050.0060.0341471621963190926.5048_hypotheticalprotein
196326___________ +1.05 +1.020.5410.3050.8313411435955348326.5519_hypotheticalprotein
196465___________ +1.17 +1.160.0250.0310.0681349415740156566.5994_conservedhypotheticalprotein
193445___________ +1.18 +1.090.3650.1860.7725032459303547546.6460_alpha-1,6-mannosyltransferase
*195674___________ -3.54 -3.530.0000.0000.00022488263437636416.6914_glycosyl-phosphatidylinositolprotein|similartoRBT5
194849___________ -1.03 -1.010.8640.8070.6782924428394289416.7362_nuclearproteininvolvedinubiquitin-dependentproteincatabolism
*193061___________ +1.09 +1.150.0270.0340.0702843831113327496.7798_mitochondrialinnermembraneprotease
193250___________ +1.01 +1.010.9170.7010.9861230012453124506.8250_splicingfactor
*195444___________ -1.42 -1.390.0010.0030.0033968028005285786.8680_innermembranetranslocasecomponent
*195908___________ +1.72 +1.820.0060.0140.0151737329828316316.9128_
*195293___________ +3.39 +4.070.0010.0030.0021264842929515086.35___
*19685____________ -2.32 -2.300.0010.0020.0024864621000211286.685__putativemitochondrialcarrierprotein
191986___________ -1.04 -1.000.5900.3650.7354416042341440906.1285_chorismatesynthase
193730___________ -1.06 -1.080.0600.1090.0731177811163108616.1829_
*192545___________ +1.43 +1.420.0000.0020.0015540879269785036.2354_derepressionoftelomericsilencing
193373___________ +1.14 +1.080.0160.0140.0891209013801130416.2887_RegulatorofIMe2expression
*192525___________ -2.75 -2.850.0000.0000.0003100761128231086116.3372_homo-isocitratedehydrogenase
192383___________ -1.16 -1.080.0980.0480.5144144535726382076.3865_Ku80componentofDNAend-joiningrepairpathway
*193394___________ +1.43 +1.380.0010.0030.0021821826057251206.4337_
191725___________ +1.17 +1.130.0100.0240.0191572018404177786.4834_
193705___________ +1.29 +1.340.0020.0060.0041722022169231166.5302_
196340___________ +1.20 +1.200.0060.0110.0191555618731186876.5769_RNApolymerasesubunit(commontopolymerasesI,IIandIII)
*196109___________ -1.65 -1.650.0040.0140.0082547741545021544206.6234_
*19809____________ +1.49 +1.700.0010.0060.0033090146040526496.6700_RNA-bindingnucleolarprotein
*196885___________ +1.16 +1.260.0020.0100.0033185037038401626.7149_CterminussimilartoproteinrequiredforpremioticDNAsynthesis
*196058___________ -1.29 -1.210.0010.0030.0078794868341728196.7602_glyoxalaseI
197148___________ +1.03 +1.030.1600.1480.2201223012646126346.8046_
*197070___________ +1.76 +2.040.0010.0040.0021612728366329706.8483_
197570___________ -1.01 +1.160.9290.9860.7364435043980513726.8918_zinc-fingertranscriptionfactoroftheZn(2)-Cys(6)binuclearclusterdomaintype
43108____________ +1.03 +1.020.4770.2570.8341240512748126154.3108_
*19563____________ +1.58 +1.670.0010.0040.0032139033831357126.367__conservedhypotheticalprotein
191356___________ +1.25 +1.150.3700.1980.6931504618739173786.1001_thiosulfatesulfurtransferase
*195534___________ +1.23 +1.380.0000.0030.0003052037504420716.1549_conservedhypotheticalprotein
19412____________ +1.01 +1.070.3770.8210.2012936629792315526.2095_involvedinco-translationalpathwayofproteintransport
*194132___________ +1.28 +1.380.0140.0540.019965581233321329896.2615_hypotheticalprotein
191155___________ +1.07 +1.040.1230.0980.2331473715713153056.3130_vacuolardiacylglycerolpyrophosphatephosphatase
*192436___________ +1.80 +1.440.0190.0130.1731689930459243736.3614_serinekinasethatphosphoryatesSRfamilysplicingfactors
*192594___________ +1.42 +1.270.0000.0010.0012968042189377166.4104_DNAdependentRNApolymeraseIsubunit
*195693___________ -2.13 -1.680.0000.0000.00012401958322737016.4575_
195611___________ +1.01 -1.011.0000.9910.9961624216372160986.5061_dihydroflavonol-4-reductases
192313___________ -1.17 -1.320.0060.0310.0092586322141195406.5537_conservedhypotheticalprotein
*196451___________ +1.48 +1.800.0180.1210.0173143646504565666.6008_polpolyprotein
*193432___________ +1.33 +1.320.0020.0040.0101635221812215836.6473_highlyconservedhypotheticalprotein
193117___________ +1.07 -1.040.4690.8980.2581805619405174206.6926_
194834___________ +1.08 +1.010.1620.0730.7361458015694147116.7377_hypotheticalprotein
196444___________ +1.03 +1.090.5110.7070.3153033431172329786.7810_RequiredforMeioticnuclearDivision
*193264___________ -1.28 -1.190.0190.0150.1194936038461415726.8264_cruciformcuttingendonuclease
*195457___________ +1.53 +1.780.0000.0020.0012278234857405346.8694_
*195893___________ -7.55 -6.670.0000.0000.0008172971082231224946.9144_componentofubiquinolcytochrome-creductasecomplex
197410___________ -1.01 +1.000.8160.5660.8971202211930120246.67___
*193599___________ +1.36 +1.260.0020.0040.0142123628865266986.703__
195754___________ +1.21 +1.140.0350.0310.1271276915455145006.1301_
193139___________ -1.11 -1.090.0450.0900.0581174810612107656.1850_
194636___________ +1.11 +1.110.0180.0210.0631399815480155766.2372_
19166____________ +1.05 +1.090.0850.1020.1241222412815133266.2902_
195052___________ +1.18 +1.120.0200.0160.1171479417402165836.3384_conservedhypotheticalprotein
193685___________ +1.07 +1.060.1010.0620.3211238813194131416.3881_PlatinumSensitivity
*195502___________ +1.58 +1.290.0010.0010.0042493239510322836.4350_hypotheticalprotein
191714___________ +1.05 +1.030.3130.1600.6981339614059138066.4847_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
193716___________ +1.10 +1.160.0240.0410.0461336314719155096.5314_hypotheticalprotein
196355___________ -1.08 -1.130.0380.2480.0271188811052105366.5784_involvedintheregulationofribosomebiosynthesis
*196094___________ +1.48 +1.350.0010.0030.0062079430677281136.6246_
*19825____________ +1.63 +1.780.0010.0030.0041924031361341586.6715_
*196901___________ +1.20 +1.140.0060.0080.0292444829405278636.7165_similartomRNAdecappingenzyme
*196071___________ +1.30 +1.070.0090.0050.3794277955489458246.7615_necessaryformitochondrialinheritance
*197160___________ +1.35 +1.360.0030.0060.0102257030530306086.8060_ankyrinrepeat-containingprotein
*197057___________ +1.61 +1.940.0010.0030.0031564525144303256.8496_glutamine-tRNAligase|glutamyltRNAsynthetase
*197586___________ +1.82 +1.850.0000.0010.0014717085625872486.8935_
6384_____________ +1.17 +1.150.0120.0130.0531263014742145636.384__
*193190___________ +1.20 +1.170.0030.0080.0104064748758473976.1023_
192928___________ -1.09 -1.140.0260.1200.0251228611257107716.1564_
191484___________ +1.27 +1.170.0060.0100.0201295616450151966.2108_hypotheticalprotein
194982___________ +1.35 +1.250.0010.0030.0041589821419198246.2629_triglyceridelipase-cholesterolesterase
63144____________ +1.10 +1.100.0310.0280.1161210513300133416.3144_
195536___________ +1.27 +1.180.0050.0080.0201263016058149566.3630_putativeamidase
*195550___________ +1.56 +1.620.0010.0040.0041640025665264876.4120_requiredformRNAdecay
194764___________ +1.15 +1.140.0080.0130.0271328815326150906.4591_componentofPab1-stimulatedpoly(A)ribonuclease
191240___________ +1.10 +1.080.0560.0700.0981397415369151106.5076_
192299___________ +1.15 +1.080.0320.0220.1871481217058160356.5551_ubiquitin-likeprotein
19723____________ +1.24 +1.150.0100.0100.0541498318637171946.6019_
*193675___________ +1.52 +1.500.0010.0010.0044604569857692786.6486_galactose-1-phosphateuridyltransferase
*193105___________ +4.40 +4.360.0000.0000.000288361268201255956.6940_cytochromeP450
196959___________ +1.04 +1.040.2470.2530.2451323613796137226.7390_firststepincommonpathwayformethionineandthreoninebiosynthesis|aspartatekinase(L-aspartate4-P-transferase)|L-aspartate4-P-transferase
196425___________ +1.07 +1.120.0180.0540.0261409615132157556.7826_
193277___________ +1.06 +1.030.1260.0730.3791312013890135786.8277_hypotheticalprotein
*195475___________ -1.24 -1.260.0030.0180.0044214133904335156.8711_hypotheticalprotein
195877___________ +1.04 +1.020.3370.1730.7221415814746144846.9160_alcoholacetyltransferase
*196018___________ +1.29 +1.510.0000.0040.0002439231463368016.91___
192654___________ +1.54 +1.340.0020.0040.0081361020999182286.721__putativetranscriptionregulator
*192166___________ +1.54 +1.440.0000.0010.0013369552031484646.1314_
191972___________ -1.08 -1.050.1650.2340.1501204311113114406.1863_conservedhyptheticalprotein
*192532___________ -1.34 -1.590.0000.0030.0014157131059261626.2386_prolyl-tRNAsynthetase,cytoplasmic
*193799___________ -1.22 -1.310.0070.0150.0204332735373330216.2917_reticulongenememberoftheRTNLA(reticulon-likeA)subfamily
195129___________ +1.36 +1.260.0020.0030.0111521920749192216.3402_conservedhypotheticalprotein
*19420____________ +9.71 +10.240.0000.0000.000175351703451794886.3895_
193503___________ +1.45 +1.320.0020.0040.0111316219051173746.4363_hypotheticalprotein
*193000___________ +1.55 +1.670.0030.0070.0111589524571264886.4865_
196166___________ +1.10 +1.020.4940.3190.5992782530554285036.5327_alpha/betahydrolase
*194899___________ -2.78 -3.380.0000.0010.0006056021763179066.5798_
*19400____________ +1.49 +1.270.0000.0010.0032962444199377026.6264_hypotheticalprotein
19516____________ -1.00 -1.080.4870.9310.2692738927352253346.6728_flippaseforMan5GlcNac2-PP-DolintheERmembrane
196913___________ +1.19 +1.270.0100.0210.0251386816532176056.7178_
196532___________ +1.13 +1.070.0450.0270.2711390615651149356.7628_mitochondrialFADcarrier
197175___________ +1.14 +1.120.0140.0180.0501591718095178416.8074_
*197347___________ +1.64 +1.700.0010.0050.0012240036800380586.8507_ubiquitin-conjugatingenzyme
*197599___________ +1.17 +1.300.0050.0470.0062825832941367626.8947_conservedhypotheticalprotein
194742___________ +1.19 +1.210.0070.0120.0221476217510178996.403__hypotheticalprotein
191434___________ +1.47 +1.380.0010.0030.0061425820949196156.1038_DNApolymeraseIIcomplexcomponent
191806___________ +1.27 +1.200.0050.0080.0251684021336201546.1580_
*191045___________ +1.59 +1.480.0020.0050.0051476523459219266.2126_
*191344___________ +3.93 +2.900.0000.0010.0011287650612373986.2644_hypotheticalprotein
*194309___________ +3.69 +3.980.0000.0000.00026456976581052406.3162_
194185___________ +1.33 +1.250.0030.0050.0151263416847158186.3642_weaksimilaritytoprotein-tyrosine-phosphatase
*19745____________ +2.50 +2.910.0000.0000.000572221432461665366.4134_vacuolememebraneproteinrequiredforvacuoleinheritance
194304___________ +1.23 +1.130.0060.0090.0281471318030166646.4608_
*196011___________ +2.05 +2.080.0000.0000.0002860058630595656.5091_transcriptionregulatoryprotein
*192667___________ +1.58 +1.790.0000.0020.0013257751529583056.5567_
196274___________ +1.14 +1.080.0470.0460.1181264614398137106.6033_hypotheticalprotein
*19430____________ +1.42 +1.330.0030.0100.0081701624190227106.6499_GTP-bindingproteinoftherabfamily
*195180___________ -1.75 -1.780.0000.0010.0012067581184681164226.6956_regulationofredoxhomeostasis
*193994___________ -1.23 -1.360.0050.0110.0164730038375348096.7407_oligosaccharyltransferasegammasubunit
*196411___________ +1.20 +1.280.0080.0190.0181648719733210856.7842_
195303___________ +1.05 -1.000.1490.0630.9721503915767149906.8292_hypotheticalprotein
*197475___________ +1.38 +1.320.0090.0150.0301559321570205616.8728_
*19675____________ -1.72 -1.930.0000.0010.000182879106412948036.132__
192681___________ +1.18 +1.140.0230.0260.0711331315648152426.741__
*191614___________ +2.50 +2.650.0000.0010.0011853546330491426.1335_
193198___________ -1.14 -1.090.0800.1790.0731181310380108696.1881_amatinglocusoxysterol-bindingprotein
194820___________ +1.08 +1.170.0610.2880.0412460226626286816.2399_conservedhypotheticalprotein
*193378___________ +2.09 +1.890.0010.0020.0061263626469239326.2935_
195201___________ -1.06 -1.060.1740.4780.1031748316465164436.3417_mitochondrialribosomalsmallsubunitprotein
195217___________ +1.08 +1.080.0890.0730.1971395615018150286.3908_acyl-CoAthioesterase
*191796___________ +1.28 +1.130.0040.0050.0352356730078266856.4375_similartoglyceratedehydrogenases
191318___________ +1.22 +1.250.0090.0160.0251584219325198806.4880_hypotheticalprotein
191581___________ +1.03 +1.020.3050.1750.5481249212882128036.5339_hypotheticalprotein
19983____________ +1.10 +1.100.0660.0640.1421252013771137346.5815_
*19388____________ +2.77 +2.510.0000.0000.0003469096061870536.6276_CCR4/NOTtranscriptionregulationcomplexassociatedfactor,ATPbinding(ABC)domain
19532____________ +1.02 -1.170.0850.9880.0404987951090425376.6743_
*193295___________ +1.32 +1.310.0020.0040.0071973225992257666.7190_hypotheticalprotein
196518___________ +1.06 +1.080.0530.0790.0811232213020133106.7641_
*197187___________ -1.35 -1.690.0020.0100.0044351432167256826.8087_mitochondrialacidicmatrixprotein
197361___________ +1.08 +1.180.0470.0910.0601283813886151316.8521_tRNA-splicingendonucleasesubunit
*197612___________ +1.70 +1.570.0000.0000.00161881105066972476.8960_cytochromecmethyltransferase
19621____________ +1.26 +1.170.0030.0040.0201265816000148166.418__
191437___________ +1.24 +1.180.0060.0150.0131931323884227416.1055_
193559___________ -1.08 -1.080.0700.1180.0841172110848108196.1603_
191077___________ +1.47 +1.200.0030.0030.0281716625313206536.2144_
194958___________ +1.13 +1.130.0080.0130.0271365515397154836.2658_proteininvolvedincellwallbiogenesisandarchitecture
19270____________ +1.15 +1.100.0120.0150.0481269214564139246.3179_hypotheticalprotein
194744___________ +1.27 +1.180.0050.0070.0241846423501217386.3656_myotubularin-relateddualspecificityphosphatase
*191691___________ +34.88 +38.910.0000.0000.000196856865847658596.4148_conservedhypotheticalprotein
*191191___________ -1.45 -1.470.0020.0060.0047183649654488706.4628_responsibleforER-associateddegradation(ERAD)ofnumerousER-residentproteins
*196127___________ -1.39 -1.480.0010.0040.0036105844029411266.5109_
*192326___________ +1.63 +1.520.0030.0050.0112105234224320686.5581_
194945___________ +1.25 +1.200.0060.0070.0321427117867171756.6046_
19445____________ -1.01 -1.030.7660.9410.5132382023675231126.6514_hypotheticalprotein
*195167___________ -1.52 -1.520.0000.0010.0013527023170232476.6969_mitochondrialtranslationinitiationfactor2
*194006___________ -1.52 -1.450.0010.0030.0033464622820238956.7419_ketopantoatereductase
*196393___________ +1.93 +2.010.0000.0020.0011777534311356476.7860_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*195316___________ +1.88 +1.810.0010.0020.0041549429098280966.8305_simtoNADHdehydrogenasesubunit5
*197488___________ +2.87 +2.650.0000.0010.0001974256665522196.8740_componentofU3snoRNP;pre-18SrRNAprocessing
196400___________ +1.15 +1.120.0160.0310.0311464016852163986.165__
192435___________ +1.25 +1.170.0050.0090.0201253115631146096.760__
*191741___________ +1.63 +1.660.0010.0040.0041404922948232846.1352_firstenzymeinsynthesisofdityrosineinthesporewall,convertingL-tyrosinetoN-formyl-L-tyrosine
192825___________ -1.10 -1.110.0210.0580.0301161010534104986.1899_conservedhypotheticalprotein
193947___________ +1.21 +1.170.0220.0290.0601621519642189286.2414_Zn-fingerprotein,transcriptionalregulator
191198___________ +1.00 -1.010.7870.5210.9581211612161119936.2947_conservedhypotheticalprotein
*191826___________ +1.47 +1.300.0020.0030.0191466921520190386.3433_mitochondrialoutermembraneproteininvolvedinmitochondrialshape
192516___________ +1.09 +1.070.0710.0510.2162452126836263286.3921_proteindisulfideisomerase
*193207___________ +1.45 +1.410.0020.0050.0091525522077215226.4392_G1cyclin
*194785___________ -1.12 -1.100.0180.0310.0424588441028415476.4895_proteinserine/threoninephosphatase2c
*191401___________ +1.94 +2.130.0000.0010.0002376746144506776.5354_putativeregulatoryprotein
*196377___________ -1.21 -1.180.0060.0100.0233271727057276286.5829_carboxymethyltransferaseforproteinphosphatase2A
*195081___________ +1.61 +1.720.0000.0010.0003650158784629456.6296_
*19544____________ -1.68 -1.450.0000.0010.00310220060708704786.6756_RNasePsubunit
*193308___________ -1.35 -1.410.0010.0030.0043879228667275196.7203_SIN3bindingprotein
196506___________ +1.25 +1.310.0060.0130.0151488518610194676.7655_
197200___________ +1.08 +1.040.1300.0740.3971281213790132726.8100_hypotheticalprotein
68533____________ +1.07 +1.020.4270.4290.3411486815921151996.8533_
*197625___________ -1.25 -1.170.0150.0150.0763187725513273146.8973_KRE1proteinprecursor
194728___________ -1.03 +1.010.9610.9880.8061211611768122826.439__
*191590___________ +1.69 +1.640.0010.0030.0021521425735250246.1068_hypotheticalprotein
194903___________ +1.17 +1.130.0170.0180.0731283914995145726.1620_N-acetylglucosaminylphosphatidylinositolde-N-acetylase
191268___________ +1.19 +1.080.0190.0150.1211285215321139246.2161_
*193166___________ +1.90 +1.770.0000.0010.0011979037568349976.2674_
194121___________ +1.10 +1.050.0830.0520.2951279414113133856.3192_peroxisomalacyl-CoAthioesterase
*192396___________ +1.58 +1.460.0010.0010.0031582624927230626.3677_alcoholdehydrogenase
*191375___________ -2.93 -2.910.0000.0010.0019519732517327276.4161_alpha-isopropylmalatesynthase
193553___________ +1.11 +1.030.1680.1200.3091979521977203346.4648_ribosomelargesubunitassembly
*196231___________ -1.26 -1.300.0350.0530.0653172225144244816.5125_
191942___________ +1.08 +1.100.0110.0360.0182044822062224176.5597_MDRtransporter
194164___________ +1.16 +1.150.0160.0270.0371257814646144606.6059_
*196632___________ +1.23 +1.310.0010.0100.0022244427595294696.6530_
195155___________ +1.07 +1.110.0340.1140.0341821519418202626.6982_
194019___________ +1.09 +1.070.2050.1600.3032486527193265746.7432_hypotheticalprotein
194579___________ +1.04 +1.060.0790.1940.0682245623378238256.7878_ER-Golgitransportvesicleprotein
*195328___________ +1.29 +1.290.0010.0030.0061760722713227456.8319_
*197501___________ +2.15 +2.260.0000.0000.0003002864412678216.8753_nucleosomeassemblyproteinI
*194970___________ +3.54 +4.310.0000.0010.0011846265445796336.180__
*192013___________ +1.21 +1.050.0170.0090.3232067725102216626.779__
1976_____________ +1.14 +1.130.0100.0140.0351394915952158126.1368_
193934___________ -1.07 -1.080.3000.6230.1691209711326111756.1912_
*194950___________ +1.61 +1.790.0020.0080.0051452523331260626.2433_ankyrinrepeat-containingprotein
19191____________ +1.13 +1.080.0170.0160.0841835020678199026.2964_proteinkinasethatinteractswithCdc31p
191163___________ -1.01 -1.040.5280.8830.3041850818383178226.3446_
*195299___________ +1.57 +2.010.0010.0060.0031822628688366746.3935_cellwallstructureorbiosynthesis
*193195___________ -1.84 -2.030.0010.0050.0013070516727151346.4405_
195728___________ +1.00 -1.000.4400.2440.7241214012170121166.4907_cytochromeP-450
*192133___________ +1.35 +1.360.0040.0070.0171579721377214496.5367_secretedlipase
*193877___________ +2.45 +3.340.0010.0040.0021450535519484186.5848_
*194394___________ +1.18 +1.070.0250.0160.2092275026761243396.6313_hypotheticalprotein
196662___________ -1.06 -1.080.0800.2210.0641521414348141016.6771_conservedhypotheticalprotein
*193322___________ +1.49 +1.330.0020.0030.0212568738318341466.7217_
*195274___________ +1.73 +1.390.0000.0000.0013230855921449836.7668_conservedhypotheticalprotein
197212___________ +1.17 +1.150.0220.0270.0651224014276140546.8112_AP-2complexsubunit,beta2-adaptin
*197385___________ +2.58 +3.500.0000.0020.0011500838760524786.8545_zincfingerprotein|spindlepoisonsensitivityrelatedprotein
197642___________ +1.17 +1.140.0240.0250.0801325915535150726.8988_
*19693____________ +1.36 +1.370.0010.0050.0041672722731229686.457__hypotheticalprotein
*191674___________ +2.12 +1.880.0000.0000.0002371250321445226.1083_ubiquitinligase(cullin)ofSCFinvolvedincellcyclecontrol
61636____________ -1.11 -1.070.0380.0550.0721179910661110256.1636_
191139___________ +1.03 +1.010.7060.4340.9777467076606752286.2177_
193159___________ +1.36 +1.330.0040.0090.0141248316956166146.2690_possiblesnoRNAbindingprotein
194072___________ +1.10 +1.070.0700.0500.2201221913396130626.3205_
19687____________ +1.17 +1.140.0050.0090.0191563218356177896.3692_hypotheticalprotein
195483___________ -1.06 -1.120.1370.2650.1082856026867255376.4177_similartoE.colielongationfactor-typeGTP-bindingproteinLepA
*64663____________ +1.98 +2.050.0010.0030.0021817035946373216.4663_
193907___________ +1.03 +1.080.1730.1370.2721237012762133706.5141_hypotheticalprotein
*191847___________ +1.72 +1.720.0010.0040.0051728229648296936.5615_
194179___________ +1.00 +1.000.5340.3170.7331194811995119906.6073_hypotheticalprotein
*196645___________ +2.88 +2.830.0000.0000.000709222041912009716.6542_highmobilitygroup-likeprotein
*196846___________ +1.70 +1.610.0010.0040.00361203103755986946.6995_cyclin-dependentkinase
*194032___________ +1.44 +1.370.0020.0040.0061849626700254226.7445_
*194593___________ +2.94 +3.050.0000.0020.0021762051802537466.7892_rhoGTPaseactivator
*195345___________ +1.35 +1.320.0010.0020.0024007454050528456.8334_requiredwithRAD23forduplicationofthespindlepolebody,ubiquitin-likeprotein
*197514___________ -6.80 -6.350.0000.0000.00025368383728173994306.8766_phosphoenolpyruvatecarboxykinase
194607___________ +1.12 +1.120.0320.0270.1341393315674156196.198__
191915___________ +1.27 +1.220.0050.0080.0171259215954153876.803__
*191301___________ +1.57 +1.460.0010.0030.0051763227750257556.1386_hypotheticalprotein
193358___________ -1.08 -1.100.0500.1780.0421170510848106076.1927_succinate-CoAligase
*192289___________ +1.43 +1.410.0000.0020.0015297675565744606.2449_actin-relatedprotein
191106___________ +1.10 +1.150.0280.0550.0461280614100146996.2982_hypotheticalprotein
*192917___________ -1.77 -1.700.0000.0000.00114693382870863156.3460_
*19911____________ +1.92 +2.040.0000.0000.0004301282762878066.3951_
*195585___________ +1.58 +1.520.0010.0040.0041508523849229836.4427_secretedaspartylproteinase5
*64921____________ +1.71 +1.800.0000.0010.0003194854735573976.4921_
*192150___________ -2.98 -3.140.0000.0000.00021281271523677826.5384_putativeelectroncarrier
*193127___________ +1.57 +1.670.0010.0040.0041767127672294846.5864_zincfingerprotein
*194382___________ +1.34 +1.300.0000.0010.0025943679682774136.6325_Golgi-to-ERvesiclecoatcomponent
196678___________ +1.09 +1.110.0310.0450.0661183212925130786.6786_
*19346____________ -1.89 -1.820.0010.0040.0036441334155353056.7230_alaninetransaminase
*195260___________ +1.80 +2.160.0020.0080.0051434825780309866.7681_
*197225___________ +1.25 +1.470.0010.0130.0012020625262297086.8126_
*197397___________ +1.22 +1.450.0030.0150.0041896923155274396.8557_zincfingerprotein
197657___________ -1.08 +1.050.1590.1820.1783091228653324156.9005_RNasePandRNaseMRPsubunit
191573___________ -1.05 -1.020.6400.3730.9898835684329867246.477__
*191092___________ +1.36 +1.380.0020.0100.0042668436263369536.1100_dol-p-mandependentalpha(1-3)mannosyltransferase
191601___________ -1.10 +1.060.4780.2700.7391223091107901301196.1651_
193719___________ +1.35 +1.220.0050.0070.0321255216945152916.2194_hypotheticalprotein
193630___________ +1.13 +1.090.0250.0280.0771273814413138936.2709_nucleolarproteinrequiredforefficientprocessingofpre-rRNAatsiteA2

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
191030___________ +1.22 +1.170.0110.0170.0321411317250165216.3221_peptidyl-prolylcis-transisomerases(PPIase)|FK506-rapamycinbindingprotein
196484___________ +1.17 +1.040.0200.0120.2511332615588138776.3711_
*194499___________ -1.40 -1.180.0040.0030.1013537925184299756.4191_mitochondrialcarrierproteinthatisrequiredforrespiration
192579___________ +1.47 +1.540.0020.0040.0061437421133220866.4679_
19218____________ +1.09 +1.050.0450.0230.4161280813967134156.5155_hypotheticalprotein
*19328____________ +1.41 +1.510.0010.0040.0032303032488347006.5630_nitrogenpermeaseregulator
192178___________ -1.22 -1.080.0180.0170.0932294218762212866.6085_RNAsplicingproteinandmemberofthemitochondrialcarrierfamily(MCF)
19666____________ +1.37 +1.340.0020.0040.0061444819813193506.6559_
196858___________ -1.04 +1.010.6610.4670.6632026019555205426.7007_conservedhypotheticalprotein
*192095___________ +1.12 +1.340.0020.0230.00281905920251095186.7460_X-Proaminopeptidase
194607___________ +1.04 +1.000.4120.2630.5471361314183136316.7906_conservedhypotheticalprotein
195363___________ -1.06 -1.060.4590.7700.2631419713390134566.8352_glycosyl-transferaseinvolvedinosmotolerance
*197529___________ +1.76 +2.000.0000.0010.0014540679971909746.8780_
1939_____________ +1.07 +1.060.0940.0860.1771249113370132046.3____hypotheticalprotein
19751____________ -1.09 -1.160.0680.0570.1732201420128189756.500__hypotheticalprotein
*193959___________ +1.40 +1.290.0240.0510.0392505635048322526.1118_
19776____________ +1.01 +1.030.3890.7570.2151209312179124396.1672_sporulationproteininvolvedinsisterchromatidcohesion
192821___________ +1.17 +1.090.4740.3170.5532482628938271086.2209_putativeNADH-ubiquinoneoxidoreductase
192710___________ +1.15 +1.120.1230.1430.1541943622444217656.2726_regulatorysubunitforproteinser/thrphosphataseGlc7p
191730___________ +1.44 +1.620.0020.0140.0041427620494231536.3235_
192798___________ -1.05 -1.060.1810.2070.1901580315103148866.3727_putativehelicase
*192344___________ -9.33 -10.380.0000.0000.00024788826564238876.4208_hypotheticalprotein
*192737___________ -1.42 -1.330.0220.0230.0805881241422441636.4693_kinase
192422___________ +1.07 +1.020.8040.9670.5532153823134219786.5172_
*19313____________ +1.11 +1.190.0210.1170.0201730219236205266.5645_
193422___________ +1.05 +1.070.1360.2460.1131247413049134066.6104_
19681____________ +1.22 +1.490.1490.1760.1681428217354212546.6574_
191901___________ +1.13 +1.110.0070.0140.0181282214429142626.7021_
*192081___________ +1.46 +1.230.0030.0050.0171818126461224166.7475_
194621___________ +1.06 +1.110.0210.0440.0371240213178137246.7920_weaksimilaritytopigtubulin-tyrosineligase
*197284___________ -2.35 -2.180.0000.0020.0013802016175174376.8365_conservedhypotheticalprotein
*196832___________ +1.46 +1.770.0010.0080.0021333019453236276.8799_bumetanide-sensitiveNa-K-Clcotransportprotein,3-primeend
ALS1_____________ -1.03 -1.060.1750.3320.126123211191511677ALS1___
*191785___________ +2.72 +2.340.0000.0000.0002449666538574416.214__
*191650___________ -2.95 -3.420.0000.0000.00015358752079449006.826__mitochondrialoutermembraneimportreceptorsubunit
*192520___________ -2.55 -2.890.0000.0010.0017120027871246296.1401_mitochondrialribosomalsmallsubunitprotein
193512___________ +1.13 +1.090.0180.0320.0401340915135146386.1946_
*193609___________ +1.48 +2.030.0010.0070.0011409820887286386.2465_partofsmall(ribosomal)subunit(SSU)processosome(containsU3snoRNA)|U3snoRNPprotein
*19797____________ +2.67 +3.160.0000.0000.0002541067818802596.2997_
19138____________ +1.16 +1.170.0090.0140.0301268514711147986.3476_integralmembraneproteinrequiredforefficientmating
*194255___________ +1.58 +1.620.0170.0720.0204217466559683076.3969_protoplast-secreted
*19305____________ -1.99 -2.060.0010.0020.0025356026958259396.4443_multidrugresistance-typetransporter
*192842___________ +3.48 +4.030.0000.0000.000357421245141440436.4936_transcriptionalrepressorsimilartozincfingerDal80
196180___________ -1.24 -1.070.1350.0940.2954422535717414316.5401_conservedhypotheticalprotein
*193141___________ +1.62 +2.060.0010.0040.0011649426740339436.5878_
*195107___________ +1.28 +1.520.0340.1520.0292130027232323746.6342_
196693___________ +1.18 +1.180.0180.0440.0291574618549186016.6802_conservedhypotheticalprotein
*194433___________ +1.19 +1.550.0080.0450.0112041924349315806.7245_
195248___________ +1.23 +1.180.3580.3520.3122956036424349986.7694_hypotheticalprotein
*197239___________ +1.58 +1.570.0120.0500.0173791660092594286.8140_
*197412___________ +1.58 +2.100.0000.0040.0011695126860356566.8572_zincfingerproteininvolvedinbudsiteselection
*197672___________ -1.29 -1.160.0170.0120.1563796929520326536.9020_conservedhypotheticalprotein
*194497___________ +1.41 +1.260.0040.0050.0201608622743202346.30___
*193626___________ +1.79 +1.930.0000.0010.0001914034253369536.522__
19799____________ +1.45 +1.300.0020.0040.0071350419557175736.1139_
*193732___________ +1.83 +1.960.0000.0000.0003434862718673956.1689_
*193603___________ +1.62 +1.970.0020.0100.0044704876315926316.2225_
193968___________ +1.19 +1.060.0190.0110.2641287215368136156.2745_hypotheticalprotein
195559___________ +1.01 +1.020.7260.4610.8991855018822188706.3251_
*193077___________ +1.24 +1.260.0030.0090.0072093626053264256.3744_
194414___________ -1.01 +1.050.3350.5900.1992106120886220946.4225_
*194655___________ +1.21 +1.220.0350.0900.0412832834398345656.4706_oligopeptidetransporterprotein
*192407___________ -1.66 -1.830.0000.0020.0017749746739422976.5186_aspartyl-tRNAsynthetase
193982___________ +1.02 -1.050.2720.9020.1351904419487180996.5658_alpha-glucosidasemaltase
192905___________ +1.14 +1.100.0310.0440.0651451916540159156.6117_hypotheticalprotein
*192763___________ +1.66 +1.600.0010.0030.0021489524761238616.6589_hypotheticalprotein
*191887___________ +1.65 +1.950.0000.0010.0003026850088590006.7033_similaritytotriacylglycerollipases
192068___________ -1.03 -1.030.5330.7560.3242040019900198676.7487_hypotheticalprotein
197007___________ +1.06 +1.020.2530.1230.6981323914084135046.7933_hypotheticalprotein
*197297___________ -1.10 +1.250.0440.2040.0346887462540860946.8378_cystathioninegamma-synthase
*196817___________ +1.62 +1.760.0020.0070.0071805129251318006.8814_zincfingertranscriptionfactorinvolvedinpleiotropicdrugresistance
Caecm39__________ +1.04 -1.020.3670.1890.752116141205511352Caecm39
*192347___________ +1.20 +1.260.0030.0150.0042547830490319896.233__
191533___________ +1.43 +1.350.0050.0060.0311348419262182186.839__conservedhypotheticalprotein
195752___________ +1.38 +1.210.0060.0080.0321293017833156286.1417_
*191917___________ +1.66 +1.700.0010.0030.0022256337413382496.1961_
*191979___________ +2.12 +2.430.0000.0000.000534231130981295566.2481_glycerophosphoinositolpermease
*191249___________ +1.27 +1.300.0020.0050.0052198527852285266.3010_phosphoribosyl-5-amino-1-phosphoribosyl-4-imidazolecarboxiamideisomerase
194266___________ +1.18 +1.120.0160.0180.0621268414985142516.3490_
194346___________ +1.22 +1.160.0150.0150.0741263715418146556.3988_
*195516___________ +1.31 +1.530.0010.0060.0023116340974476676.4458_signalrecognitionparticleprotein
*195850___________ +1.35 +1.790.0020.0620.00261952838981111956.4952_conservedhypotheticalprotein
196208___________ +1.36 +1.350.0030.0060.0121513220624203906.5417_
192251___________ +1.16 +1.130.0330.0360.0911252514473141066.5895_adenineaminohydrolase|adeninedeaminase
*192003___________ -1.33 -1.460.0050.0170.0088031860536551036.6357_cholinepermease
196708___________ +1.29 +1.140.0140.0140.0771278816460145416.6817_nicotinamidase|pyrazinamidase
*194446___________ +1.10 +1.280.0060.0580.0063028033381386666.7259_putativepermease
195235___________ -1.04 -1.070.1360.2100.1271777617089166876.7707_hypotheticalprotein
197255___________ -1.01 +1.070.9180.8200.7716626865556706356.8155_DNA-directedRNApolymerasessmallsubunit
*197427___________ +1.50 +1.680.0000.0010.0003186147768535036.8587_conservedhypotheticalmembraneprotein
*196003___________ +2.87 +2.660.0000.0000.0002084059776553616.9034_conservedhypotheticalprotein
193748___________ +1.16 +1.210.0030.0140.0061304715083157736.46___hypotheticalprotein
191813___________ +1.35 +1.350.3750.8020.2014221456797568276.540__
191346___________ +1.17 +1.140.0170.0840.0181478017258169186.1159_hyphallyregulatedcellwallprotein
199______________ +1.16 +1.100.2810.1280.9841377116008151436.1707_
191389___________ +1.02 -1.070.7560.8020.5291933619741180266.2241_
*194216___________ -5.82 -4.830.0000.0010.00137223264007770766.2761_heatshockprotein
192862___________ +1.20 +1.080.1950.2170.2021956923469212136.3268_GTPcyclohydrolaseII,firststepinriboflavinbiosynthesis
194912___________ +1.35 +1.280.0030.0100.0081671022498213736.3759_conservedhypotheticalprotein
191286___________ -1.07 -1.020.2160.1280.4461306812238127616.4239_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*19575____________ +1.41 +1.620.0030.0180.0041729924397281026.4722_
194286___________ +1.15 +1.290.0030.0330.0041359415699174696.5200_hypotheticalprotein
196141___________ -1.00 -1.150.0780.3540.0491918919113166296.5673_high-affinityhexose(glucose)transporter
192892___________ -1.00 -1.010.6610.8020.4281204711992118816.6130_hypotheticalprotein
194243___________ +1.06 +1.140.0470.1170.0501393814782158746.6602_
*191873___________ -1.32 -1.460.0090.0170.0242932122146201186.7047_
192054___________ -1.03 -1.110.2030.2780.1732043219912183746.7501_hypotheticalzincfingerprotein
197021___________ +1.26 -1.150.2910.5690.1701418881783911232096.7947_glycogenphosphorylase
197311___________ +1.04 +1.140.0790.4910.0431494215499170916.8392_hypotheticalprotein
196804___________ -1.01 +1.070.0870.6820.0431225212183131206.8827_signalrecognitionparticle68
Cakre99__________ -1.03 -1.060.2250.4180.148119841165811350Cakre99
194063___________ +1.28 +1.110.0070.0060.1171260316113140306.248__
194975___________ +1.23 +1.170.0180.0330.0361581219377184266.856__
*192633___________ +1.66 +1.660.0080.0410.0113685561220610006.1438_quinatepermease
*191952___________ -1.52 -1.660.0020.0070.0054660230583279956.1977_
*193683___________ +1.45 +1.610.0010.0080.0021405220368226926.2496_
193227___________ +1.11 +1.280.0080.0570.0091319414630168636.3026_potentialirontransporter
193967___________ +1.15 +1.140.6740.7620.4511283501478721469116.3504_6-phosphofructokinase,alphasubunit
192939___________ +1.04 +1.100.2190.2650.1981305613569143576.4003_conservedhypotheticalprotein
193175___________ -1.12 -1.140.1470.0990.3213875634493341166.4472_
192468___________ +1.20 +1.170.0140.0280.0301373416469160896.4967_trans-aconitatemethyltransferase1
196194___________ +1.17 +1.250.0030.0250.0051514417729189416.5430_hypotheticalprotein
*194928___________ +1.85 +2.010.0000.0010.0012234641431448456.5908_GDP/GTPexchangefactorforSec4p
191409___________ +1.29 +1.320.0020.0110.0051512319459200276.6379_
194104___________ +1.04 +1.080.1310.4060.0801287913358138546.6832_diguanylatecyclase/phosphodiesterasedomain-containingprotein
*19905____________ -1.24 -1.310.0260.0380.0596663153590510026.7272_aminoacidtransporter
196975___________ +1.28 +1.210.6680.8850.421932561191171132566.7721_ribosomalproteinS0A
197270___________ -1.13 -1.020.6300.4080.7216960461868683116.8170_hypotheticalprotein
197441___________ +1.11 +1.230.0070.1530.0061685418780207926.8601_conservedhypotheticalprotein
195989___________ +1.03 +1.030.6040.5530.4711378414223141876.9049_
19377____________ +1.20 +1.140.0100.0090.0831282115358145526.66___
192401___________ +1.64 +1.530.0010.0020.0021292021225197226.561__anchorproteinthatmediatesattachmentofautophagosomestomicrotubules
19145____________ -1.00 -1.030.8560.7660.6891200211967116626.1177_RNApolymeraseIIfourthlargestsubunit
195576___________ +1.18 +1.130.0100.0130.0441399816511157846.1724_panthotenatekinase,3-primeend
196044___________ +1.29 +1.090.0040.0040.0501357617492148176.2258_
191153___________ -1.10 -1.100.1320.0880.3074460940455404166.2779_
193613___________ +1.30 +1.220.0040.0060.0161310717035159956.3284_
194365___________ +1.12 +1.080.0220.0170.1361481116519159746.3773_
191834___________ +1.29 +1.210.0030.0060.0151532619704185656.4252_nuclearporecomplexsubunit
193348___________ +1.00 -1.000.7700.8410.5341683216836168016.4739_
*194808___________ +1.57 +1.560.0010.0030.0032395037651372436.5214_nucleoporin|nucleartransport
19593____________ +1.16 +1.100.0180.0170.0891637619048180116.5685_
195835___________ +1.04 +1.050.1440.1690.1652237023207234366.6143_involvedinpre-rRNAprocessingandribosomeassembly
194228___________ -1.07 -1.040.6300.9970.3815383250287515156.6617_conservedhypotheticalprotein
19506____________ +1.01 +1.150.0870.8560.0423120431584358796.7064_
193821___________ +1.13 +1.070.0360.0340.1111441416323153636.7516_hypotheticalprotein
*197034___________ +1.49 +1.550.0020.0090.0062057430675319836.7960_hypotheticalprotein
197323___________ +1.06 +1.080.0990.3090.0682440825874264076.8404_corticosteroid-bindingprotein
*196791___________ +3.06 +3.110.0000.0010.0012504276542778086.8840_histoneH3
41841____________ +1.12 +1.140.0120.0300.0231444416201164874.1841_
*19493____________ +1.50 +1.520.0030.0080.0075945889058905336.269__
*193680___________ +1.75 +1.370.0020.0040.0161492726131205086.875__septininvolvedincytokinesis
19259____________ +1.37 +1.180.0060.0070.0421319618122155506.1454_hypotheticalprotein
19251____________ +1.02 -1.010.6370.9730.3872570426335254616.1991_conservedhypotheticalprotein
*194123___________ +1.80 +1.450.0030.0050.0131429925725207786.2512_playsaroleintranscriptionalelongation
191701___________ +1.12 +1.040.0470.0430.1311326814802138556.3042_ribose-5-phosphateketol-isomerase
194702___________ +1.26 +1.140.0060.0070.0311272416020144596.3519_hypotheticalprotein
*194746___________ +1.27 +1.380.0040.0160.0082252028695310216.4016_JumonjiInteractingProtein
*193192___________ +1.12 +1.150.0470.0380.1583037934026350626.4488_
193478___________ -1.02 +1.390.0700.9050.0333954038700549736.4981_nucleolarproteinrequiredfor60Sribosomesubunitgenesis
196296___________ +1.13 +1.070.2160.1420.3831276814457136436.5446_involvedinglucosederepression
1929_____________ +1.03 +1.050.2020.1370.3571267313029133656.5923_hypotheticalprotein
*191421___________ +1.59 +1.530.0000.0000.0003341653165509826.6390_ureidoglycolatehydrolase
*194090___________ -1.80 -1.760.0000.0010.0014732826257269616.6846_conservedhypotheticalmembraneprotein
*19891____________ +2.25 +2.310.0010.0040.0051543334732356326.7287_
196987___________ +1.09 +1.190.3780.6190.2265091255401605406.7733_dynaminGTPaseinvolvedinreceptor-mediatedendocytosisandmitochondrialorganization
19935____________ +1.08 +1.000.1860.0810.9771229513248123436.8184_hypotheticalprotein
*197453___________ +1.64 +1.420.0010.0020.0031910331327271436.8613_hypotheticalprotein
195975___________ +1.03 +1.030.4020.2160.7281226112646125886.9062_zincfingertranscriptionfactor
195606___________ +1.10 +1.060.5250.2830.9711218813443129646.94___
195770___________ +1.10 +1.350.0020.0420.0021279214093173196.582__
191123___________ +1.16 +1.080.0480.0490.1161216014087131676.1198_hypotheticalprotein
193150___________ +1.01 +1.070.1670.7650.0821239712560132706.1740_similartoplantdihydroflavonol4-reductase
196257___________ +1.04 +1.050.1390.1590.1661248813032131506.2271_
194340___________ +1.02 +1.020.5960.5160.4891257812837127746.2797_hypotheticalprotein
194918___________ +1.03 +1.020.3170.1790.5721228312637125096.3297_conservedhypotheticalprotein
195725___________ +1.04 +1.050.3540.3850.2831218312612128076.3794_hypotheticalprotein
192222___________ +1.08 +1.100.3800.6310.2262140223202235986.4267_caseinkinaseI
192106___________ -1.01 -1.010.6760.4050.9821458614460144086.4755_conservedhypotheticalmembraneprotein
194149___________ -1.04 -1.040.4690.3540.4751552214932149546.5230_hypotheticalprotein
192986___________ -1.00 +1.020.6220.8920.3791215812145123986.5703_conservedhypotheticalprotein
195821___________ -1.02 -1.020.7550.9280.5021181411552115756.6156_
195799___________ +1.11 +1.060.5720.6890.3733276936521347156.6633_conservedhypotheticalprotein
*19491____________ +1.17 +1.110.0310.0620.0462025823751224666.7080_involvedinproteinimportintoER
193836___________ -1.05 -1.020.2210.1080.6571251811973122516.7531_conservedhypotheticalprotein
195035___________ -1.02 +1.010.6730.5860.5391273012528128816.7974_proteininvolvedinhistonegenetranscriptionregulation
197336___________ -1.03 -1.040.3140.3500.2591180011498113466.8417_similartoMFSeffluxtransporter
196779___________ -1.04 -1.050.0870.1680.0841272312197120786.8852_gamma-glutamylphosphatereductase,Prolinebiosyntheticenzyme
42327____________ -1.02 -1.020.7720.7240.5841195911770116884.2327_
191871___________ +1.22 +1.130.0040.0050.0321242615182140516.284__
*193728___________ +1.51 +1.470.0020.0080.0051840427853270516.896__
194793___________ +1.29 +1.290.0040.0160.0071377117742178136.1469_conservedhypotheticalprotein
194476___________ +1.25 +1.230.0030.0110.0071257915737154596.2004_
191783___________ +1.32 +1.310.0020.0070.0041276316884166816.2530_
*194796___________ +1.43 +1.400.0040.0080.0141814625960253906.3055_bindstoeIF-4E,themRNAcap-bindingprotein
19646____________ +1.12 -1.050.7140.5460.6503334037477317556.3535_
195098___________ +1.11 +1.120.0590.1050.0741285514300143586.4034_
195632___________ -1.12 -1.030.4740.2520.8579189582053892476.4501_glycophospholipid-anchoredsurfaceglycoprotein
194518___________ +1.13 +1.100.0920.1660.0921572617712173616.4993_serine/threonineproteinkinase
194677___________ +1.12 +1.080.0230.0310.0601258214036135966.5459_weaksimilaritytoprobablecyclinG1interactingprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
19206____________ +1.04 +1.030.3820.2240.5971236812846127256.5937_
*191546___________ -1.59 -1.740.0010.0040.0022918518405167326.6404_conservedhypotheticalprotein
*196709___________ -1.63 -1.830.0030.0070.0076028436943329166.6858_similartoepoxidehydrolase
19876____________ +1.01 -1.130.3090.3200.2724390644235389766.7301_hypotheticalprotein
196999___________ +1.04 +1.020.3980.2370.5971227312747124936.7745_taurinecatabolismdioxygenase
19947____________ -1.15 -1.190.0070.0310.0101854116057156326.8196_mitochondrialribosomalprotein
*195390___________ +1.58 +1.700.0000.0030.0011868129550317316.8626_hypotheticalprotein
195963___________ +1.09 +1.100.0890.1100.1231348214698148176.9074_conservedhypotheticalprotein
*194873___________ +5.70 +5.090.0000.0000.00018021102780917836.113__
194068___________ +1.28 +1.230.0030.0050.0151244415875152476.604__
191350___________ +1.30 +1.140.0050.0060.0311251216209142026.1214_
194704___________ +1.06 +1.020.1370.0620.6812357525060240666.1758_
193773___________ +1.26 +1.190.0040.0070.0131265815899150206.2290_weaksimilaritytodouble-strandedribonuclease
*19409____________ +1.33 +1.430.0000.0010.0014704262780673806.2819_conservedhypotheticalprotein
*193649___________ +1.43 +1.220.0050.0050.0501914227277233196.3312_
192558___________ +1.19 +1.140.0110.0140.0401275815227146086.3807_hypotheticalprotein
*193534___________ +1.38 +1.330.0010.0020.0024558363093605586.4280_GTP-bindingproteinoftherhofamily
192374___________ +1.22 +1.320.0830.2490.0621885423050249496.4772_retrotransposongagprotein
*193859___________ -1.27 -1.250.0180.0250.0515049439677403166.5249_hypotheticaloxidoreductase
*192972___________ +2.02 +1.890.0000.0010.0012212944728417586.5717_nucleotidephosphodiesterase
*192489___________ +1.33 +1.320.0000.0020.0013108641434410246.6170_ranbindingprotein|homologofimportin-beta
*192967___________ -1.64 -1.680.0000.0010.0017968148499473456.6649_translationinitiationfactoreIF3,p39subunit
191478___________ -1.08 -1.050.2080.3620.1472388122079228056.7095_oligosaccharyltransferasesubunit|integralERmmebranesubunitrequiredforproteinglycosylation
196561___________ +1.02 +1.020.5390.3110.7792182522243221726.7548_
*195022___________ +1.14 +1.110.0200.0240.0642821132276314436.7987_manganeseiontransporter
*197123___________ -1.39 -1.300.0450.0380.1481523501097761172206.8430_hypotheticalprotein
*196763___________ +1.33 +1.260.0120.0300.0231474841960351859126.8867_
42581____________ +1.04 +1.030.4340.2900.5281175212260120594.2581_
192537___________ +1.24 +1.110.0390.0230.2771309116216145166.298__hypotheticalprotein
191298___________ +1.30 +1.200.0060.0070.0351360317749163856.923__nuclearporecomplexsubunit
194955___________ +1.37 +1.290.0020.0040.0101519220742196656.1488_sporulation-specificprotein2precursor
62027____________ +1.28 +1.160.1810.2630.1551275416332148446.2027_
19805____________ +1.07 +1.070.1060.0740.2631789019146190576.2546_conservedhypotheticalprotein
193796___________ +1.12 +1.140.0560.0430.1811279514303145266.3069_ribonucleaseIII
19857____________ +1.39 +1.180.0040.0050.0301384719295163836.3555_
193929___________ +1.03 -1.000.7830.7140.6062045621108204486.4047_
*195646___________ +1.07 +1.060.0430.0310.1792146422953227776.4515_conservedhypotheticalprotein
194214___________ +1.28 +1.280.0040.0080.0151308216769167846.5007_hypotheticalprotein
*193743___________ +1.11 +1.170.0400.2860.0273287936367385556.5473_hypotheticalprotein
195144___________ +1.07 +1.050.1120.1100.1761558416667164176.5954_
*191560___________ -1.36 -1.220.0020.0030.0264786035250392876.6418_
*196724___________ -4.08 -4.780.0000.0010.0018484920806177636.6873_mitochondrialfumaratehydratase,5-primeend
*196928___________ -1.36 -1.080.0470.0200.766131153966281216046.7314_secretedaspartylproteinase9
193023___________ +1.23 +1.220.0150.0270.0361369016810166446.7761_
*19962____________ +1.78 +2.010.0000.0020.0013167656356637026.8211_hypotheticalprotein
*195406___________ +1.41 +1.480.0070.0140.0191396019655207016.8642_phosphatase
*195949___________ +1.15 +1.140.0040.0130.0092293826443260666.9088_
19141____________ +1.09 +1.140.0130.0710.0141239213471141236.128__
195203___________ +1.08 +1.110.0550.0940.0731180812780131056.627__
193168___________ +1.15 +1.040.7260.8310.4882421827850252686.1236_componentof19Sproteasomeregulatoryparticle
*61776____________ +1.47 +1.370.0090.0190.0221761525936242116.1776_
193848___________ +1.04 +1.070.1630.2590.1371223912723131266.2310_
194969___________ +1.02 +1.000.7570.4860.9651217912441121856.2836_
19701____________ +1.02 +1.030.8980.8520.7131234012576127186.3325_ferricreductase
192641___________ +1.05 +1.060.1430.2300.1271194412483126976.3822_centractin-actin-relatedproteinofthedynactincomplex
19300____________ -1.04 -1.040.2330.1580.3811410913593136276.4293_mitochondrialD-lactatedehydrogenase
195628___________ +1.00 +1.070.2670.6890.1421233712367131776.4787_mitochondrialdicarboxylatetransportprotein
196551___________ +1.02 +1.020.8620.6560.8231279913075130016.5263_SNAREproteinwithaC-terminalmembraneanchor
*191263___________ +1.20 +1.260.0110.0620.0131668220096210106.5730_ferricreductase
195771___________ +1.03 +1.020.6690.4170.8261242012845126226.6187_PAB1bindingprotein
*192954___________ -1.34 -1.970.0040.0210.0056238846565316216.6661_
*191464___________ +1.21 +1.200.0180.0310.0401519418449182266.7109_genefamilyofunknownfunction
196577___________ -1.01 -1.020.7140.5630.6281186411714116386.7564_
195009___________ -1.02 +1.000.6610.5040.6051715416841171846.8000_Kelch-repeatcontainingprotein
197109___________ -1.05 -1.060.1110.1410.1351452813804136926.8444_ankyrinrepeatprotein
196752___________ -1.06 -1.070.1790.2140.1811230511592115496.8879_mitochondrialribosomesmallsubunitcomponent
42768f++2________ -1.03 -1.040.4260.5040.3011177511446113134.2768f
*193599___________ +1.30 +1.290.0060.0090.0232324230264300566.317__
*19156____________ +1.33 +1.220.0180.0670.0232497433100303976.938__hypotheticalprotein
*191133___________ +1.84 +1.890.0010.0040.0011802733180340896.1504_
193528___________ +1.34 +1.280.0020.0080.0061490419951190576.2041_conservedhypotheticalprotein
193788___________ +1.11 +1.150.0090.0320.0141241213764142276.2559_
191212___________ +1.10 +1.110.1920.4540.1181832020085203056.3085_requiredforinositolmetabolism
*192270___________ +2.23 +2.160.0000.0030.0012542256743548366.3571_manganesetransporter
*193915___________ +1.85 +1.960.0010.0040.0021587229430311106.4061_
196222___________ +1.12 +1.110.0280.0660.0401385315531153236.4534_sporulation-defective
*194199___________ +1.45 +1.760.0030.0130.0061371419864241706.5022_
192699___________ -1.15 -1.350.0550.1150.0639589783429712206.5488_
195131___________ +1.10 +1.100.0370.0560.0651233713581135686.5967_
191639___________ +1.14 +1.100.0250.0560.0381253114348138026.6432_
*195647___________ +1.34 +1.290.0280.1260.0272567734331332206.6887_
196942___________ +1.10 +1.110.4950.5520.3493490838515388836.7328_Or(ISS)nrecognitioncomplex
193037___________ +1.10 +1.240.2740.7740.1411180521297301467156.7774_3'-endRNA-processingcomplexcomponent
19976____________ +1.25 +1.310.0090.0170.0231227415300160876.8226_
*195419___________ -4.22 -4.670.0000.0000.00035534484199760876.8655_F1F0-ATPasesubunit
195933___________ -1.03 -1.060.1340.2810.1011210411721114306.9104_hypotheticalprotein
19625____________ +1.39 +1.200.0060.0050.0611254617394150836.144__
19999____________ +1.17 +1.120.0080.0090.0451263414720140986.650__
191841___________ +1.22 +1.120.0050.0080.0221246015144139066.1253_hypotheticalprotein
*19680____________ -2.06 -1.970.0000.0000.0007657937202389156.1796_
192503___________ +1.22 +1.140.0060.0090.0311296815856147696.2326_hypotheticalprotein
*19461____________ +2.35 +2.490.0020.0060.0061438633812358726.2853_hypotheticalprotein
*193333___________ -1.82 -1.730.0000.0010.00314814881556857096.3340_polyadenylatedRNAbindingprotein
194878___________ +1.34 +1.250.0650.0760.1143394245530425106.3838_
*194478___________ -1.40 -1.200.0010.0020.0103539025202294476.4309_aspartyl-tRNAsynthetase
*19277____________ +1.13 +1.200.0030.0350.0042868432512345486.4806_thiamin-phosphatepyrophosphorylaseandhydroxyethylthiazolekinase
*196538___________ +1.53 +1.540.0030.0100.0073954660319609956.5276_
*191667___________ +1.16 +1.250.0060.0380.0073375439243422106.5742_DNA-dependentATPaseofthenucleotideexcisionrepairfactor4complex
196592___________ -1.22 -1.030.1040.0450.7724222534496409366.6204_membranetransporter
*194528___________ +1.31 +1.310.0030.0090.0082336030562305426.6674_conservedhypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*191449___________ -3.83 -3.580.0000.0010.0015625914707157226.7124_cyanamidehydratase(byhomology)
*196033___________ +1.34 +1.310.0020.0040.0052232730012293366.7577_
194993___________ +1.04 +1.040.2590.1940.3512088021751217746.8015_vesicularfusionprotein
197096___________ -1.10 +1.050.6460.5650.519105311960341101386.8457_conservedhypotheticalprotein
*196738___________ +1.49 +1.570.0020.0070.0071534122843240726.8893_vanadateresistanceprotein
43029____________ -1.00 -1.030.6990.8320.4591172611697113404.3029_
*191357___________ +6.49 +7.890.0000.0000.000455392955383592666.332__
*19238____________ -1.40 -1.260.0110.0110.0719791969854776536.956__
*195067___________ +1.51 +1.410.0020.0070.0041929629112271946.1520_conservedhypotheticalprotein
*19367____________ +2.25 +1.870.0010.0020.0031648237133308746.2057_
*193367___________ +1.40 +1.500.0000.0020.0012656637185397736.2578_conservedhypotheticalprotein
194566___________ +1.14 +1.070.0330.0210.2381420416149152306.3098_membraneprotein
192754___________ -1.13 -1.170.0520.0690.0902358420872201566.3586_translocaseofthemitochondrialinnermembrane
192364___________ +1.26 +1.240.0030.0060.0101777322425220306.4076_tetrahydrofolatesynthase
*1958_____________ +1.58 +1.680.0010.0050.0033603457021606256.4548_ribosomalRNAprocessing3'-5'exonuclease
191969___________ -1.03 -1.030.4430.2990.5272282722066220716.5035_cellwallmannoproteininvolvedincellstressresponse
196313___________ +1.19 +1.210.0040.0160.0061937023033234146.5506_similaritytomannosyltransferases
192042___________ +1.01 +1.000.9910.9730.9082252822746225906.5981_mitochondrialGTPaseinvolvedintranslation
*191626___________ -1.55 -1.470.0000.0000.0013846624834261096.6446_deoxyhypusinesynthase
*195661___________ -1.62 -1.490.0000.0010.0028480252474570046.6901_conservedhypotheticalprotein
*194864___________ +1.92 +1.770.0010.0020.0021861435816330176.7347_
*193050___________ +1.27 +1.270.0030.0070.0092101426600267196.7787_GTPaseactivatingprotein
193239___________ +1.11 +1.070.1610.0950.4001241613745132716.8239_chromosometransmission
*195432___________ +1.37 +1.420.0010.0060.0022983240950423766.8668_tRNA2-phosphotransferase
195919___________ +1.18 +1.170.0040.0070.0141513217920177266.9118_conservedhypotheticalprotein
1940_____________ +1.19 +1.130.0350.0350.1071292415369146116.5____
191219___________ -1.04 -1.060.3250.5560.1981161011196109686.671__
*191910___________ -1.15 -1.360.0010.0140.0024444338791326926.1269_putativeoxydoreductase
*193455___________ +1.41 +1.330.0010.0030.0041967327721261896.1814_mitochondrialtransmembranetransporter
193897___________ +1.44 +1.390.0380.0260.1861560322516216616.2342_hypotheticalprotein
191768___________ +1.17 +1.110.0150.0150.0701644819284183326.2869_conservedhypotheticalprotein
192646___________ -1.10 -1.080.0310.0800.0381167810580108186.3357_
19841____________ +1.43 +1.190.0050.0060.0411358419449161526.3852_
193407___________ +1.05 +1.040.5180.3420.6031931120365200306.4324_DNArepairproteinandATPase
*19610____________ +5.72 +6.420.0000.0000.000242971389081558966.4820_
*193000___________ +1.84 +1.800.0010.0030.0021963836037353786.5289_
*193573___________ -1.28 -1.630.0010.0110.0014653936257284666.5756_peroxisomalassemblyprotein|AAAATPase
196606___________ +1.08 +1.060.0860.0630.2321304914087137966.6218_conservedhypotheticalprotein
*194540___________ +4.98 +4.600.0000.0000.000372201853161710836.6686_E2ubiquitin-conjugatingenzyme
*196873___________ -1.44 -2.200.0020.0300.0025198323601122364826.7137_ribosomalproteinS8E
*196046___________ +2.07 +1.690.0000.0010.0022312847784389996.7590_subunitofanaphase-promotingcomplexandubiquitinligase
*197131___________ -3.88 -4.730.0000.0000.00012347631812260986.8031_conservedhypotheticalprotein
197082___________ +1.01 -1.020.9660.9020.8451943619636190026.8471_mitochondrialcarrierprotein
197557___________ +1.39 +1.230.0070.0110.0311305818199160306.8905_hypotheticalprotein
43073f--2b_______ -1.01 -1.000.9990.9660.9941158411420115664.3073f
*191087___________ +2.42 +2.030.0010.0020.0041732241839352076.351__
191351___________ +1.44 +1.240.0110.0140.0421403420159173686.978__hypotheticalprotein
192867___________ +1.15 +1.080.0230.0160.1541519217472164056.1535_involvedinGolgiretentionandvacuolarsorting
191384___________ +1.45 +1.410.0020.0060.0071708224734240286.2079_
*193774___________ +1.26 +1.210.0080.0110.0383613645387437316.2595_
191711___________ +1.15 +1.070.0250.0170.1911426416418152836.3116_requiredforcytoskeletalorganization
192784___________ +1.11 +1.010.1180.0540.6311567617340158936.3601_hypotheticalprotein
*191760___________ +1.20 +1.300.0140.0450.0204717256576614536.4089_smallmonomericGTPaseinvolvedinhyphaedifferentiationandthetransmissionofcAMPsignals
*195683___________ -2.29 -1.770.0000.0000.00114191061975803176.4561_conservedhypotheticalmembraneprotein
195857___________ +1.01 +1.030.9960.9720.9423504435286359916.5049_hypotheticalprotein
*196327___________ +1.14 +1.320.0010.0060.0011128181283601488896.5520_involvedinnonallelicheterokaryonincompatibility
*196462___________ -1.07 -1.150.0240.2950.0163091628917269216.5997_conservedhypotheticalprotein|conservedhypotheticaltransmembraneprotein
193444___________ +1.01 +1.000.8360.5810.9611757917727176106.6461_putativeMFS-MDRtransporter
*195675___________ +1.30 +1.270.0050.0090.0174743361899601186.6915_SNF2familyDNA-dependentATPase
*194848___________ +1.24 +1.180.0060.0150.0122305228519272156.7363_antiviralproteinwithtetratricopeptiderepeats
*193062___________ +1.53 +1.460.0000.0010.0012074631683303106.7799_conservedhypotheticalprotein
193251___________ -1.04 -1.060.2710.4400.1811712016528161776.8251_structuralprotein
*195445___________ +1.71 +1.480.0000.0010.0043253055630482556.8681_GTP-aseactivatingproteinforArf
195906___________ +1.05 +1.110.3470.7680.1865106553778567746.9131_phosphoribosylamino-imidazole-carboxylase|purinebiosynthesis
*195294___________ +1.54 +1.400.0020.0050.0081287619772180896.36___
194860___________ +1.31 +1.140.0140.0110.1261459019183166996.687__hypotheticalprotein
196222___________ +1.31 +1.320.0010.0040.0041475219265194336.1288_
*193727___________ +1.73 +1.640.0010.0020.0031667928813273826.1832_
192547___________ -1.03 -1.070.0780.1250.0922261421931211916.2356_
193371___________ +1.20 +1.090.0150.0130.0961216414631132616.2889_conservedhypotheticalprotein
192525___________ +1.11 +1.120.6620.4190.7894491849915504476.3371_
192382___________ +1.66 +1.470.0010.0020.0041439123958211546.3866_isoleucine-tRNAligase
192203___________ +1.21 +1.130.0100.0100.0551284415484145716.4338_hypotheticalprotein
*191724___________ +1.38 +1.130.0060.0060.0661602622150181806.4836_hypotheticalprotein
193706___________ +1.23 +1.250.0320.0460.0641468518052183556.5303_
196341___________ +1.02 +1.100.4380.7880.2452677827300294786.5770_secondstepintheriboflavinbiosynthesispathway|5-amino-6-(5-phosphoribosylamino)uracilreductase
*196109___________ -1.64 -1.800.0000.0030.00111821571981655686.6235_
19810____________ +1.18 +1.170.0070.0100.0341508017804176946.6701_C4zincfingerDNA-bindingproteinoflowsequencespecificityinvitro|probable119kDaDNA/RNAhelicasefamilymember
*196886___________ +1.54 +1.690.0000.0010.0002540039235428076.7150_conservedcoiledcoilsprotein
*196059___________ -3.91 -3.000.0000.0000.000309970792131034876.7603_glutaredoxin
197148___________ -1.00 +1.030.7840.8060.5621453514469149826.8047_
*197068___________ +1.39 +1.480.0020.0060.0051691823451249796.8485_metal-bindingtranscriptionfactor
*197571___________ +2.03 +2.090.0000.0000.0002762856116576516.8919_Ubiquitin-conjugatingenzyme
43108____________ +1.14 +1.090.0190.0200.0781235614036134454.3108_
19564____________ +1.00 -1.010.3560.3970.2791388913929137016.369__
191355___________ +1.18 +1.190.0250.0320.0661381416307164426.1002_6-phosphogluconolactonase|multicopysupressoroflos1-1
195535___________ -1.06 +1.020.3900.2030.7682037219230208496.1550_
*19411____________ +3.83 +3.840.0000.0010.0011628862459625966.2096_hypotheticalprotein
194131___________ +1.32 +1.160.0090.0090.0601293217025150326.2617_
191156___________ +1.01 +1.020.7430.7220.5461184411924121336.3132_
192437___________ +1.22 +1.080.0290.0170.2681216014859131216.3615_Arpcomplexsubunit
*192593___________ +1.36 +1.340.0020.0040.0124356259338583476.4106_
*195698___________ -1.99 -2.020.0000.0000.0014618623157229196.4577_
195610___________ -1.03 -1.050.1060.1140.1571745616992166876.5062_ornithinecarbamoyltransferase
192312___________ +1.33 +1.280.0030.0060.0121292617203165866.5538_ferricreductase
19734____________ -1.12 -1.030.7060.4400.9062747022447942678296.6009_aldohexosespecificglucokinase
*193431___________ +1.74 +1.900.0000.0020.0012012134946381416.6474_mitochondrialDNApolymerasecatalyticsubunit
193117___________ -1.12 -1.110.0970.0970.1602000017818179576.6928_mycelialsurfaceantigen,similartoRBT5
*194833___________ -6.32 -8.830.0000.0000.00037069858699419996.7378_malatesynthase
196443___________ -1.45 -1.220.0990.0460.5712245815479183416.7811_enoyl-CoAisomerase|delta3-cis-delta2-trans-enoyl-CoAisomerase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*193265___________ -1.35 -1.080.0300.0140.5713061222631283846.8265_N2,N2-dimethylguanosine-specifictRNAmethyltransferase
195459___________ +1.26 +1.150.0080.0080.0701795822632205966.8696_
195892___________ +1.23 +1.280.0030.0120.0071896923249242546.9145_ubiquitin-proteinligase
*194683___________ +1.39 +1.160.0080.0100.0391666423136193086.68___
*193599___________ +1.58 +1.280.0160.0170.0673486855225445976.704__
*195755___________ +1.89 +1.510.0010.0030.0062254642506339676.1303_
193140___________ +1.25 +1.170.0090.0090.0651257615732147036.1851_hypotheticalprotein
*194635___________ +1.89 +1.870.0020.0070.0061325325074248366.2374_
*19166____________ +2.22 +1.810.0000.0010.0012688259602486726.2903_
195051___________ +1.42 +1.390.0060.0110.0191291018366179356.3385_conservedhypotheticalprotein
*193684___________ -2.55 -3.640.0000.0000.00010753442143295666.3882_
195503___________ +1.16 +1.160.0090.0140.0341368115864158146.4351_hypotheticalprotein
195776___________ +1.08 -1.290.1650.5860.0882643592857522050806.4848_ubiquitin-proteinligase
*196154___________ +1.13 -1.010.0140.0080.4628647598109853426.5315_conservedhypotheticalprotein
196356___________ -1.26 -1.220.0020.0070.00611863938897176.5785_snRNP(U4/U6)-associatedsplicingfactor|RNAsplicingfactor
*196092___________ +2.18 +2.130.0020.0060.0041735237823370386.6248_
19826____________ -1.17 -1.130.0080.0150.021115629882102286.6717_hypotheticalprotein
196902___________ -1.14 -1.090.0240.0600.0341222110710111626.7166_Dead-boxprotein|RNAhelicase
196072___________ -1.15 -1.160.0070.0270.0121175610228101176.7616_hypotheticalprotein
197161___________ -1.10 -1.130.0160.0810.0171161010578102916.8062_
197056___________ -1.15 -1.140.0100.0190.0251172410161102906.8497_dicarboxylicaminoacidpermease
197588___________ -1.23 -1.130.0130.0350.023117649601104206.8936_conservedhypotheticalprotein
19618____________ +1.24 +1.140.0080.0070.0681239515414140816.385__hypotheticalprotein
193188___________ +1.28 +1.210.0030.0050.0181830623420221296.1024_
196249___________ +1.23 +1.170.0080.0090.0421398917151163856.1565_
191485___________ -1.19 -1.350.0140.0460.0212672722427198296.2109_mitochondrialribosomalprotein
*194984___________ +1.55 +1.600.0000.0020.0011613825046258866.2631_
194976___________ +1.32 +1.260.0060.0090.0241491619746188316.3146_
19752____________ +1.21 +1.090.0100.0110.0591326215988144726.3631_
*195551___________ +3.06 +2.940.0000.0000.0002648380919778186.4121_requiredfornormalchromosomesegregationandspindleintegrity
194763___________ +1.32 +1.250.0010.0030.0051720922722214636.4592_hypotheticalprotein
191239___________ +1.05 +1.060.0670.0860.1041222212794129366.5078_hypotheticalprotein
192297___________ +1.29 +1.200.0020.0040.0071681021698202296.5553_
*196263___________ -1.81 -2.030.0000.0000.00010085055653495866.6022_conservedhypotheticalprotein
193676___________ +1.25 +1.260.0040.0130.0101480418572186056.6487_putativemethyltransferase
*193104___________ -1.18 -1.090.0300.0300.0976595655719603086.6941_alkalinedihydroceramidase
*196960___________ +2.65 +2.630.0010.0030.0011628143123428576.7391_
196425___________ +1.09 +1.040.1430.0750.4811255213720130626.7827_
*193278___________ +3.85 +4.250.0000.0000.000287771106921221916.8278_glycogen(starch)synthase
197460___________ +1.26 +1.350.0020.0110.0051447718202195176.8712_conservedhypotheticalprotein
*195876___________ +2.02 +1.990.0000.0000.0004468690467887366.9161_hypotheticalprotein
193433___________ +1.23 +1.140.0210.0150.1631344516572153176.92___
192655___________ +1.30 +1.270.0050.0090.0151285016728162666.722__
191225___________ +1.46 +1.220.0560.0820.0841340919631163836.1316_hypotheticalprotein
*191971___________ +2.32 +2.420.0000.0010.0012042047279495046.1864_conservedzincfingerprotein
192532___________ +1.38 +1.240.0020.0030.0101407019460175036.2387_
62918____________ +1.09 +1.060.0540.0350.2381233513432130246.2918_
195126___________ +1.07 +1.070.7590.8750.5141601917079170946.3404_
19418____________ +1.36 +1.300.0030.0040.0171265417259164766.3897_KontrollerOfGrowth
193504___________ +1.06 -1.090.4150.4270.3286106364498559466.4364_ribosomalprotein
*193000___________ +1.61 +1.660.0000.0010.0012552841209423466.4866_
196167___________ -1.17 +1.040.2660.1220.8837689865990799136.5328_1-Acyldihydroxyacetonephosphatereductase
19998____________ +1.30 +1.280.0020.0060.0081684721913215006.5800_hypotheticalprotein
19399____________ +1.10 +1.210.1160.1440.1421395201541561682036.6265_ser/thrproteinkinase
19517____________ +1.09 +1.050.0930.0450.5212157823582225996.6729_Histone-liketranscriptionalactivatorofrespiratoryfunctions
*196915___________ +1.17 +1.260.0060.0270.0092744632049345846.7179_requiredfordoublestrandbreakformation&resection
*196531___________ -2.11 -2.260.0000.0010.00010193448250452006.7629_NADH-ubiquinoneoxidoreductase49kDasubunit,mitochondrialprecursor
*197176___________ +2.27 +2.230.0000.0010.0011686438346376866.8076_nicotinatephosphoribosyltransferase
*197349___________ +1.62 +1.760.0020.0060.0052327237591410376.8509_chitinsynthaseregulatoryfactor
*197600___________ -3.31 -2.670.0000.0000.0003620901093161356536.8948_glutathione-dependentformaldehydedehydrogenase
194743___________ +1.14 +1.040.6840.6450.5131369815590142056.404__
191433___________ +1.11 +1.050.0560.0240.6941649518353172866.1039_predictedacetyltransferasesandhydrolaseswiththealpha/betahydrolasefold
191806___________ +1.14 +1.050.0510.0330.2331290914702135836.1581_hypotheticalprotein
191047___________ +1.17 +1.080.0240.0200.1201240214571134336.2128_
191342___________ +1.03 +1.040.6500.3880.8961569016104162426.2646_
194312___________ +1.26 +1.110.0320.0350.0891458418331161606.3165_
194186___________ +1.20 +1.140.0190.0170.0991260715138143126.3643_phosphorylcholinetransferase|cholinephosphatecytidylyltransferase
19746____________ +1.10 +1.040.2770.1280.8591225313421127716.4135_hypotheticalprotein
194305___________ -1.02 -1.030.8650.8500.6601377113524134026.4610_conservedhypotheticalprotein
196012___________ +1.13 +1.000.0450.0200.7321242614020124416.5092_conservedhypotheticalprotein
*192340___________ +1.50 +1.700.0000.0010.0002131631993362486.5569_
196275___________ -1.02 +1.020.6150.4140.6672250422047229236.6034_ribosomalproteinkinases
19431____________ -1.02 +1.000.7870.6520.6612166721273217506.6500_potentialfungalZn(2)-Cys(6)binuclearclusterdomain
195179___________ +1.02 -1.010.5120.2780.8771211412315119566.6957_secretedlipase
193995___________ -1.07 +1.010.5800.3470.7742436222858244986.7408_calpain-likeproteaseinvolvedinproteolyticprocessingofRim1p/Rim101p,cysteineprotease
196408___________ +1.07 +1.080.1390.1290.2052271424384244346.7844_
195304___________ -1.02 -1.040.6860.6670.5031427314061137306.8293_hypotheticalprotein
*197477___________ +1.52 +1.760.0000.0000.0002869843744506116.8729_GTPase-activatingprotein
*19122____________ +1.77 +1.320.0050.0060.0371491026417197276.139__
192682___________ -1.03 -1.080.3240.8660.1661195411598110606.742__
191611___________ +1.36 +1.240.0030.0050.0141292817541159956.1337_
193199___________ +1.26 +1.180.0070.0090.0311286316164152286.1882_amatinglocusphosphatidylinositol4-kinase
194819___________ -1.02 +1.020.3970.6260.2392077620351211426.2400_hypotheticalprotein
193376___________ +1.11 +1.090.0360.0310.1341321914722144696.2936_
63418____________ +1.21 +1.110.0400.0300.1691235614911137166.3418_
195218___________ +1.14 +1.020.0540.0270.4561504017110153526.3909_
*191797___________ +2.96 +3.080.0000.0020.0011610047630495976.4376_conservedhypotheticalprotein
191321___________ +1.28 +1.210.0020.0050.0101473618832178426.4881_
191580___________ -1.19 -1.140.0100.0200.024115899779101986.5340_hypotheticalprotein
19589____________ -1.26 -1.170.0070.0150.018117009308100386.5816_Rab5-likeGTPaseinvolvedinvacuolarproteinsortingandendocytosispostvesicleinternalization
19387____________ -1.16 -1.100.0120.0250.0261185610237107646.6277_largesubunitofthenuclearpre-mRNAcap-bindingproteincomplex
19532____________ -1.19 -1.140.0030.0060.0161209710207106556.6744_hypotheticalprotein
193296___________ -1.19 -1.160.0040.0110.010116979870100906.7191_hypotheticalprotein
196517___________ -1.17 -1.130.0050.0120.0151174210052104306.7643_Zn-bindingnucleotideexisionrepairosome
197188___________ -1.22 -1.120.0040.0100.013117949687105586.8089_60Slargesubunitacidicribosomalproteina1
197362___________ -1.17 -1.130.0080.0330.013117019996103466.8522_glucansynthasesubunitinvolvedincellwallassembly
197613___________ -1.13 -1.140.0130.0640.0151168810365102266.8961_translationinitiationfactor3subunit
6419_____________ +1.28 +1.140.0040.0050.0391288016531146566.419__
*194690___________ +1.51 +1.350.0040.0060.0161291219470174246.1056_
193558___________ +1.28 +1.100.0060.0060.0661719522005189736.1604_p24proteininvolvedinmembranetrafficking

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
191077___________ +1.37 +1.170.0020.0030.0201655622723194506.2145_
*194956___________ +1.85 +2.040.0000.0030.0011933435856395246.2659_
19269____________ +1.10 +1.040.4510.2420.7922351625814243406.3180_seryl-tRNAsynthetase
194744___________ +1.23 +1.140.0060.0070.0471620819875184156.3657_
*191690___________ +1.68 +1.520.0020.0040.0061631127360247726.4150_
*191193___________ +2.27 +2.680.0000.0000.000516441170411384686.4630_
196129___________ -1.40 -1.410.0030.0100.0062419217281171266.5111_
192325___________ +1.30 +1.220.0040.0080.0131554720170189596.5583_91kDatau91subunitoftranscriptionfactorIIIC(TFIIIC)
*194943___________ -1.28 -1.620.0000.0100.00010302280334637096.6047_mannose-1-phosphateguanyltransferase
19446____________ +1.26 +1.180.0150.0240.0411503618949177066.6515_hypotheticalprotein
195166___________ +1.20 +1.150.0190.0260.0521663520001191926.6970_regulatorofCdc7kinase
194007___________ +1.07 -1.010.5050.2770.8262564227522254206.7420_conservedhypotheticalprotein
196392___________ -1.02 +1.030.9930.9450.9351951819150201856.7862_hypotheticalprotein
195318___________ +1.15 +1.060.0420.0310.1731555417815165586.8306_
*197489___________ +1.31 +1.300.0020.0050.0041982526024257456.8741_GTPase-activatingproteinoftherho/racfamily
192919___________ +1.31 +1.140.0120.0070.2371248316336142446.166__
192433___________ +1.20 +1.130.0060.0070.0461319615860148556.762__
19799____________ +1.41 +1.240.0030.0040.0271341018955166726.1353_betasubunitofheterotrimericGprotein
*192826___________ +1.47 +1.280.0030.0050.0151567823008201466.1900_hypotheticalprotein
193949___________ +1.38 +1.320.0030.0060.0111520820964200856.2415_
194488___________ +1.09 +1.020.1400.0640.6751299614170133166.2948_
191827___________ +1.26 +1.120.0360.0210.3001290816271144516.3434_hypotheticalprotein
196018___________ -1.04 +1.010.9340.8310.8032707526028273936.3922_phospholipid:diacylglycerolacyltransferase
193205___________ -1.05 -1.130.0250.0860.0282329922287206346.4394_mitochondrialribosomeLSUproteinL36
194786___________ +1.16 +1.100.0230.0220.0951301715145143296.4896_hypotheticalprotein
191402___________ +1.03 +1.050.9910.9180.9532237623117234356.5355_cytoplasmicchaperoninoftheCctringcomplex
196378___________ +1.14 +1.080.0390.0280.1811286014646139226.5830_conservedhypotheticalprotein
*195079___________ +1.20 +1.210.0040.0120.0103566042796431536.6297_ABCtransporter
195441___________ +1.13 +1.110.0260.0210.1251534417318169656.6757_20Sproteasomesubunit(alpha4)
193309___________ +1.34 +1.240.0020.0030.0131727923138213836.7204_hypotheticalGAGprotein
196506___________ +1.14 +1.090.0210.0170.1191255114362136606.7656_
197201___________ +1.09 +1.200.3830.6180.2301339751460511610376.8101_structuralconstituentofcytoskeleton
*197374___________ +2.69 +2.920.0010.0030.0021785547982520866.8534_zincfingertranscriptionfactor
197626___________ +1.00 -1.010.5400.2950.9352225222295221236.8974_mRNAcap-bindingproteineIF4E,translationinitiation
194865___________ +1.02 +1.020.3790.1850.9791186612141120736.440__
191591___________ +1.06 +1.030.5040.2690.9321740718416179886.1069_acetyl-CoAacetyltransferase|acetoacetylCoAthiolase
61622____________ +1.08 +1.050.2140.1250.4581278013833133966.1622_
191270___________ +1.14 +1.110.0390.0230.2611211013842134506.2163_
193163___________ +1.10 +1.040.1400.0630.6831183813049123606.2675_
194120___________ +1.07 +1.050.3760.1950.7581213712943126966.3193_cellmorphogenesis,cytoskeletalregulationandbudformation
192395___________ +1.08 +1.010.2490.1120.9761316014251132686.3678_positiveregulatorofmeiosis,ser/thrproteinkinase
191376___________ +1.19 +1.060.0850.0620.2271230414609130676.4162_syntaxin|post-Golgit-SNARE
193552___________ +1.16 +1.150.0200.0400.0381482417241170226.4649_nuclearporeprotein
196230___________ +1.06 +1.020.3550.1940.6481224812933125176.5126_enhancesfunctionofnuclearexonucleaseRat1
191941___________ +1.05 +1.010.4340.2350.7511224912865123206.5598_spindlepolebodyprotein
194166___________ +1.09 +1.070.2830.1850.4331264113769135826.6060_fungalZn(2)-Cys(6)binuclearclusterdomain
*196634___________ +1.35 +1.330.0010.0030.0062408232560319326.6531_vacuolarATPaseV1domainsubunitB
66983____________ -1.00 +1.010.6420.3990.7941182411785119456.6983_
194021___________ -1.01 -1.010.7160.8320.4771691716715167506.7433_
194580___________ -1.01 -1.030.9550.8980.8161234312195119296.7879_conservedhypotheticalprotein
195328___________ +1.08 +1.010.2220.1220.5161262613580127046.8320_
*197502___________ +2.52 +2.700.0000.0000.0002890372908780646.8754_hypotheticalprotein
193954___________ -1.13 -1.110.0140.0260.0341167410295105546.181__
194057___________ +1.01 -1.080.4650.5660.3141193112051110966.784__
1975_____________ +1.28 +1.160.0030.0050.0141430518257165476.1370_possibleexocystcomponent
193932___________ -1.06 -1.080.2350.4860.1441173911064108556.1913_
194948___________ +1.16 +1.130.0060.0090.0281310815194148456.2434_
19192____________ -1.15 -1.130.0140.0420.0211173310240103666.2965_conservedhypotheticalprotein
195205___________ +1.19 +1.120.0410.0400.1161396716664156956.3448_hypotheticalprotein
195297___________ +1.33 +1.210.0040.0050.0281309817473158706.3936_
*194040___________ +1.30 +1.200.0030.0060.0112402231318287086.4406_
195729___________ +1.34 +1.170.0060.0070.0431528820548178776.4908_transcriptionfactor
192135___________ -1.13 -1.120.0180.0680.0221209710663108056.5368_
*193877___________ +1.96 +1.920.0010.0030.0031794035195344386.5849_hypotheticalprotein
194393___________ -1.08 -1.120.0130.0480.0191177010931105336.6314_nuclearcitratesynthase
196663___________ -1.13 -1.160.0090.0360.0141359412049117416.6772_ribosomalproteinS25
19334____________ -1.10 -1.080.0350.0490.0701168510616108186.7218_hypotheticalprotein
195274___________ -1.12 -1.120.0140.0490.0191156110277103316.7669_
197213___________ -1.15 -1.150.0050.0170.0111178010275102236.8113_ATP-dependentRNAhelicase
197386___________ -1.16 -1.110.0110.0230.0261165210032104976.8546_assemblyofmitochondrialrespiratorycomplexes
197642___________ +1.08 +1.070.1060.0640.3291262013595134676.8989_
19693____________ +1.26 +1.130.0070.0060.0901265916003143146.456__
191673___________ +1.32 +1.260.0030.0050.0111291217047162136.1084_serine/threonineproteinphosphatase
*193080___________ +1.67 +1.600.0010.0040.0061599526778255376.1638_
*19465____________ +1.44 +1.480.0030.0090.0102882441393425206.2178_
*193158___________ +1.63 +1.850.0010.0050.0021432523278264716.2691_involvedinmeioticnucleardivision
194072___________ +1.03 +1.010.3750.1960.7351214912463123046.3206_
19686____________ +1.34 +1.210.0080.0110.0321304817471157336.3693_conservedhypotheticalprotein
*195484___________ -1.68 -1.630.0000.0010.0008488550570522176.4178_3-phosphoserinetransaminase
195493___________ +1.13 +1.020.0710.0300.8378582497208874286.4664_smallnuclearGTPaseoftherassuperfamily
193906___________ +1.05 +1.020.1620.0720.7521218412757124386.5142_hypotheticalprotein
*191849___________ +1.29 +1.430.0010.0060.0021842223741264356.5616_conservedhypotheticalprotein
194180___________ +1.08 -1.000.1690.0910.4891743418899174226.6074_signalrecognitionparticlereceptorinvolvedinmembraneproteininsertionintotheER
*196645___________ +1.99 +1.740.0000.0000.0003551670768619116.6543_
*196847___________ +1.41 +1.430.0010.0050.0041745224569249536.6996_conservedhypotheticalprotein
194032___________ +1.01 +1.060.8190.5700.8934556046035483506.7447_non-ATPaseunitof26Sproteasomecomplex
194594___________ +1.05 +1.010.3130.1610.6871161812161117656.7893_clathrinlightchain
195346___________ +1.30 +1.100.0130.0090.1541404218279154266.8336_
197516___________ -1.02 -1.110.0190.3430.0122564525136230606.8767_
191100___________ +1.36 +1.130.0050.0050.0501281417444144846.200__
194117___________ +1.27 +1.150.0040.0040.0481270616200145636.805__
*191300___________ -1.89 -2.170.0000.0010.0015578529526257306.1387_conservedhypothticalprotein
193359___________ -1.02 -1.010.8830.7640.7391171711494115596.1928_
*192290___________ +1.61 +1.510.0000.0010.0021619726104244776.2450_1-phosphatidylinositol3-kinase
191107___________ +1.18 +1.180.0200.0300.0471313315544154486.2983_conservedhypotheticalprotein
*192916___________ -1.75 -2.040.0010.0080.0028991251511441806.3462_hypotheticalprotein
193767___________ +1.18 +1.080.0140.0090.2221253914805135116.3953_
*195586___________ +1.83 +1.770.0010.0020.0031629029731288266.4428_pheromone-inducedprotein,suppressorofsac1mutation
*191067___________ +2.32 +2.580.0000.0000.0003870089657997666.4922_phosphoglyceratemutase
192151___________ -1.28 -1.260.1080.1310.1386774753082535606.5386_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
193128___________ -1.14 -1.060.3870.2700.4687910269086749216.5865_t-SNARE-interactingproteinthatfunctionsinER-to-Golgitraffic
*194381___________ +1.26 +1.450.0000.0010.00176990973361117726.6326_polyphosphatesynthetase
*196679___________ +1.95 +1.660.0010.0020.0081413427509234876.6788_aldolase
*19347____________ +1.74 +1.590.0010.0010.0033560162001566346.7231_hypotheticalprotein
*195260___________ +1.25 +1.270.0100.0200.0254341854072549276.7682_proteasomeregulatorysubunit
*197227___________ +1.30 +1.310.0000.0010.0012794036414367186.8127_conservedhypotheticalprotein
197424___________ +1.14 +1.130.0510.0870.0705993068599675076.8558_
197658___________ -1.08 -1.030.1560.1280.2512779625694270396.9007_
191571___________ +1.07 +1.040.2000.1330.3661245213315129216.478__Ady2-Fun34likeFamily,possibletransmembraneacetatefacilitator/sensor
*191091___________ +1.64 +1.930.0010.0040.0011887430900364616.1101_nucleolarproteinrequiredfor60Sribosomebiogenesis
192618___________ -1.18 +1.020.1100.0460.8693790532048387216.1653_homoserineO-acetyltransferase
193718___________ +1.68 +1.330.0140.0100.1541297221752172406.2195_peptidetransporter
193629___________ +1.17 +1.090.0270.0170.2101254914659136596.2710_WDdomainprotein
191029___________ +1.09 +1.040.1590.0990.3701178112897122896.3222_nuclearribonucleasePsubunit(RNaseP)|requiredforprocessingoftRNAand35SrRNA
196482___________ +1.06 +1.060.1400.1190.2281233113088130596.3712_hypotheticalprotein
*194502___________ +1.13 +1.180.0380.0640.0603038234223357286.4192_
192580___________ +1.20 +1.170.0160.0180.0661270415284149036.4681_similartoHst1pandSir2pputativehistonedeacetylases
19217____________ +1.07 +1.040.1810.1100.4071274613632132446.5156_zincfingerprotein
*19327____________ +1.74 +1.360.0030.0040.0201398324294190426.5631_histonevariantinvolvedinchromatinandtranscriptionalcontrol
192177___________ +1.05 +1.010.2340.1120.7171186712497120276.6086_
19666____________ +1.06 +1.030.1180.0520.7421419815057146496.6560_DNAdamageresponsecellcyclecheckpointprotein
196859___________ +1.04 +1.020.1750.2270.1671244112879126566.7008_hypotheticalprotein
*192094___________ +1.09 +1.150.0260.0950.0282738929985314656.7461_memberofthekaryopherin-betafamilywithpossibleroleinnucleartransportandregulationofpleiotropicdrugresistance
194608___________ +1.05 +1.020.2800.7710.1441207212721123056.7907_pyruvatedecarboxylaseI
195364___________ +1.18 +1.130.0230.0260.0711487617608167626.8353_rnabindingprotein
*197531___________ -1.36 -1.140.0260.0210.1344428832516390096.8784_
*1943_____________ -1.21 -1.500.0000.0220.0003541429232235916.8____hypotheticalprotein
196277___________ +1.28 +1.210.0040.0060.0201294116601155956.501__
*193957___________ +1.22 +1.140.0150.0110.1482790233995317186.1119_GTPcyclohydrolase
*194336___________ -1.36 -1.920.0000.0020.0002102081550431092246.1675_ribosomalsmallsubunitprotein
*196463___________ +1.33 +1.210.0010.0020.0143803850582460486.2211_
*192711___________ +1.16 +1.120.0080.0120.0302321827044259896.2727_RNApolymeraseIIElongatorsubuni
*191729___________ +2.49 +2.130.0000.0010.0011770343995377666.3236_hypotheticalprotein
*192799___________ +1.20 +1.140.0070.0110.0292679632253304276.3728_essentialforGPIanchorattachment
192343___________ +1.44 +1.450.0880.2670.0641615623313233786.4209_putativeubiquitinreceptorimplicatedinvacuolartargetingofplasmamembraneproteins
192738___________ +1.11 +1.130.6280.3960.7525691963202645076.4694_highaffinitysulfatepermease
*192422___________ -1.29 -1.380.0010.0060.0014609835851334426.5173_
*193970___________ +1.53 +1.660.0020.0070.0051786427344295946.5646_conservedhypotheticalprotein
193420___________ +1.07 +1.070.0630.1120.0751270713547135456.6105_hypotheticalprotein
*192774___________ +2.17 +2.430.0000.0010.0011875240618455326.6579_
191900___________ +1.14 +1.190.0070.0260.0131564317903186326.7022_
*192079___________ +1.42 +1.320.0040.0040.0383927055825517546.7476_pterin-4a-carbinolaminedehydratase
*194622___________ +2.61 +3.060.0000.0020.0012283259617699196.7921_hypotheticalprotein
*197285___________ -1.37 -1.570.0000.0010.0007739856515493946.8366_conservedhypotheticalprotein
*196831___________ +2.30 +2.630.0010.0040.0031663638273437726.8800_pre-mRNAprocessingRNA-helicase
42957____________ +1.00 -1.040.5780.6150.4071221812249117084.2957_
19227____________ -1.03 -1.210.2910.4150.2053193330900263616.215__cytochrome-coxidase,subunitVII
191651___________ +1.34 +1.190.0030.0040.0241405418824166746.827__hypotheticalprotein
*192521___________ +1.85 +1.640.0010.0020.0031540128541253156.1402_
193512___________ +1.15 +1.090.0170.0190.0661689419413183666.1947_
193610___________ +1.19 +1.190.0070.0110.0231342716033159236.2466_transmembraneprotein
*19797____________ +3.42 +2.490.0000.0000.0002431783194605206.2998_
*19137____________ +2.52 +2.030.0000.0020.0011546938922314296.3477_acetyltransferase
194253___________ +1.18 +1.190.0120.0210.0311282415151152046.3970_
*19306____________ +1.78 +1.640.0000.0010.0012023036036331416.4444_interaptininvolvedinERtoGolgiproteintransport
*192843___________ +2.26 +2.010.0000.0000.0002382195386184796786.4937_GTP-bindingprotein,rhosubfamily
*196181___________ -1.26 -1.240.0020.0050.0043467527450280176.5402_
*192265___________ +1.41 +1.420.0010.0020.0023957855677560536.5881_subunitofSWI/SNFtranscriptionactivationcomplex
*195106___________ +1.50 +1.710.0010.0080.002739551112321263016.6344_betatransducin
196694___________ +1.18 +1.130.0070.0090.0301470017375166726.6804_
*194435___________ +1.82 +2.140.0040.0100.0121379825113294996.7246_
195247___________ +1.03 -1.030.4550.2450.7935083852473495736.7695_conservedhypotheticalprotein
197242___________ +1.21 +1.190.0100.0150.0311392816846165506.8141_
*197413___________ +1.47 +1.480.0010.0020.0021838526941272116.8573_lowhomologytoproteininvolvedinDNArepair
*197673___________ -1.17 -1.190.0270.0540.0435467746707458986.9021_snRNA-associatedprotein,snRNP
*194496___________ +1.37 +1.310.0010.0020.0024306058928564716.31___conservedhypotheticalmembraneprotein
*19712____________ +1.73 +1.540.0010.0030.0061488025794229886.523__
19193____________ +1.19 +1.190.0070.0100.0341313615591155806.1142_
193732___________ +1.37 +1.310.0010.0030.0031753023930228916.1690_membrane-boundnon-hemedi-ironoxygenaseinvolvedinlipidmetabolism|C-4sterolmethyloxidase
193601___________ +1.31 +1.250.0030.0060.0151359217872170236.2226_replicationfactorATPase
*193969___________ +1.32 +1.150.0090.0080.0901355817950156556.2746_heat-shockrelatedprotein
*195558___________ +1.86 +1.790.0000.0010.0011939636141347686.3253_
*19849____________ +1.65 +1.610.0010.0040.0041324621793213216.3745_
194413___________ -1.05 +1.040.6140.6860.4173248433084723363866.4226_
194656___________ +1.11 +1.130.0090.0120.0411427815904161766.4707_lowsimilaritytoABCtransporters
192406___________ +1.12 +1.080.0520.0610.1011533317142165856.5187_
193983___________ +1.15 +1.150.0040.0130.0091813620905209096.5659_conservedhypotheticalprotein
*192903___________ +1.93 +1.660.0000.0010.0012527448860418976.6118_
*192762___________ -2.16 -1.970.0000.0000.0012984241382421516986.6590_alkylhydroperoxidereductase
*191886___________ +1.43 +1.550.0010.0050.0013102644416479846.7034_
192067___________ -1.00 -1.100.0280.7860.0152379123762216826.7488_nitrogenfixingprotein
197009___________ +1.06 +1.070.3280.5880.1941425815172152626.7934_
*197298___________ -1.72 -1.550.0010.0020.0023047617749196516.8380_
*196816___________ -2.32 -1.780.0000.0000.0018840338059497376.8815_aldehydereductase
Caexg2___________ -1.09 -1.050.2060.5870.113121451118411552Caexg2_
*194147___________ -1.33 -1.070.0010.0010.2297062052990657296.234__
191207___________ +1.22 +1.110.0090.0100.0461260615417139776.840__hypotheticalprotein
*194784___________ +1.44 +1.310.0020.0030.0151404620249184206.1418_
*191915___________ +1.69 +2.020.0010.0040.0022580843698521696.1963_
*191978___________ -1.42 -1.320.0020.0030.0143324323375252646.2482_glycerophosphoinositolpermease
191248___________ -1.06 -1.090.1390.1370.1924316640709394586.3011_45kDasubunitofRNApolymeraseII
*194266___________ +1.19 +1.290.0030.0180.0041699620268218856.3491_septin
*194346___________ +1.54 +1.330.0020.0030.0111543423787205796.3989_
*195517___________ +1.29 +1.330.0050.0320.0072581033354342066.4459_alcoholdehydrogenase
*195851___________ +1.16 +1.290.0030.0330.0042715431540350696.4953_dipeptidylaminopeptidase
*196208___________ -1.66 -1.810.0000.0010.0015591333761309566.5418_
*192250___________ -1.83 -1.700.0000.0000.00110157655475597376.5896_spermidinesynthase|putrescineaminopropyltransferase
*192002___________ +1.46 +1.540.0000.0010.0002623938262403136.6358_nucleoporin
*194118___________ +1.28 +1.370.0020.0040.0132935137553401266.6818_
*194447___________ +1.78 +1.740.0010.0020.0021613428706280996.7260_mitochondrialcarrierprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
195233___________ +1.02 -1.020.2590.8850.1281386814077135736.7709_hypotheticalprotein
197257___________ -1.07 -1.030.5430.3250.7293634033971351586.8157_DNAmismatchrepair
*197428___________ +2.13 +2.100.0000.0010.0002146245739451246.8588_apurinic/apyrimidinicendonuclease/3'-repairdiesterase
196002___________ -1.17 -1.150.0030.0050.0182039617495176786.9035_ribosomalproteinL8B(L4B)(rp6)(YL5)
194079___________ +1.32 +1.180.0020.0040.0121463619353172656.48___
19846____________ +1.23 +1.140.0110.0110.0571249115403142246.541__
191805___________ +1.14 +1.140.0100.0130.0401459316623166156.1160_peroxisomalproteininvolvedinimportofperoxisomalmatrixproteins
194691___________ +1.08 +1.050.0620.0460.2041250713495131166.1708_
*191390___________ +1.93 +1.590.0010.0020.0042034239187323266.2242_
194217___________ +1.08 +1.110.0390.0440.0941350214630150286.2762_
192859___________ +1.16 +1.180.0170.0230.0511411816367166416.3272_
193457___________ +1.18 +1.120.0150.0140.0861272814958142886.3760_
*191285___________ +1.94 +1.790.0000.0010.0014222881989755766.4240_conservedhypotheticalprotein
*19575____________ +1.42 +1.360.0010.0030.0052168430766294616.4723_
194284___________ +1.01 +1.000.5960.3460.8621265912770127236.5201_
196139___________ +1.03 +1.020.3360.2920.3381300413336133146.5674_
192891___________ -1.06 -1.110.0450.1270.0461491414049134136.6131_ATPase
194242___________ +1.35 +1.240.0010.0020.0061576321298195126.6603_serine/threoninekinase
*191872___________ -1.73 -2.030.0000.0010.00013217776341652176.7048_
*193809___________ +1.49 +1.400.0040.0090.0122001829863279606.7502_
*197022___________ +2.42 +2.420.0000.0010.0021952247260472796.7948_hypotheticalprotein
*197312___________ -1.03 -1.250.0030.0640.0035503753667441026.8393_3-hydroxy-3-methylglutarylcoenzymeAsynthase
*196803___________ +1.36 +1.370.0010.0040.0041977826898270696.8828_UDP-galactosetransporter
Cancx1___________ +1.04 -1.020.4830.3180.571118371232811569Cancx1_
194063___________ +1.49 +1.290.0010.0020.0091331819875171806.249__
192781___________ +1.31 +1.130.0080.0070.0661273816693144276.859__Ca/calmodulin-dependentser/thrproteinkinase
192634___________ +1.29 +1.340.0030.0090.0061311016899176026.1440_
191953___________ +1.25 +1.200.0040.0090.0131532419090183706.1979_hypotheticalprotein
193682___________ -1.00 +1.090.4540.5650.3042006819987219466.2497_generationofmannoproteinlayerofthecellwall|putativephosphatase
193228___________ +1.15 +1.120.0180.0200.0701343715441150346.3027_conservedhypotheticalprotein
193966___________ +1.36 +1.270.0010.0040.0041297617594164516.3505_congoredhypersensitive,Cellwallprotein
192940___________ +1.24 +1.150.0060.0080.0251309316274150526.4004_ER-to-Golgiv-SNARE
*193176___________ +1.26 +1.300.0070.0100.0313225840577418026.4473_unknownfunction
*192467___________ +1.41 +1.460.0030.0060.0101587822440232366.4968_RNApolIItranscriptioncofactor
*196193___________ +1.61 +1.620.0020.0050.0071528724604247996.5431_TFIIDsubunit,5-primeend
194929___________ -1.00 -1.040.4440.7920.2492331423251223196.5909_involvedinexpressionofmitochondrialCOX1
191409___________ +1.11 +1.190.0740.1140.0943931743710469106.6378_vacuolarmembraneprotein
*194102___________ -1.30 -1.320.0030.0100.00710104677514766006.6833_
*19904____________ +1.23 +1.150.0040.0070.0162346428962269956.7273_hypotheticalprotein
*196976___________ +1.74 +1.960.0000.0010.0002338240681458436.7722_multidrugeffluxprotein
197271___________ +1.17 +1.100.0080.0090.0551737320322190746.8171_hypotheticalprotein
197442___________ -1.11 -1.100.0120.0190.0352894426061263226.8602_lowhomologytomismatch-specificthymineDNAglycosylase
195987___________ +1.09 +1.090.0590.0430.2031398415302152706.9050_conservedhypotheticalprotein
19634____________ +1.32 +1.200.0020.0050.0121337117615161016.71___hypotheticalprotein
192402___________ +1.46 +1.240.0020.0030.0181525322309189056.563__
19145____________ +1.24 +1.230.0030.0050.0121331016478163466.1178_
195578___________ +1.28 +1.150.0060.0060.0561284116453147596.1725_
62259____________ +1.09 +1.070.0430.0420.1141523116602163606.2259_
*191150___________ +1.34 +1.420.0010.0030.0011922625718272276.2781_zincfingertranscriptionfactor
193615___________ -1.03 +1.080.4370.7520.2493260731794350926.3285_conservedhypotheticalprotein
194363___________ +1.27 +1.180.0030.0060.0121279616188151036.3774_
*191833___________ +1.75 +1.880.0060.0260.0101049301840821969116.4253_nucleolarpseuduridinesynthaseandputativemicrotubulebindingprotein
*193349___________ +1.70 +1.850.0000.0010.00055841948791031036.4740_
194809___________ -1.23 -1.240.0020.0060.0062706821980218736.5215_mevalonatekinase
*19593____________ +1.68 +1.930.0020.0060.0051407023571272246.5686_
195834___________ +1.08 +1.060.0420.0350.1452161623422229616.6144_suppressorofmRNAexportmutant|importin-betalikegene|karyopherinbetafamilymember|putativebeta-karyopherin
194227___________ +1.22 +1.280.0000.0020.0011566419084200146.6618_hypotheticalprotein
*19505____________ -1.57 -1.400.0000.0010.00213582886731968466.7066_adenylatecyclase-associatedprotein
*193822___________ -1.76 -1.600.0000.0000.0013737002125982330876.7517_inositolphosphorylceramide-BC-26hydroxylase|ERdesaturaserequiredforthehydroxylationoftheverylongchainfattyacid(VLCFA)
197035___________ +1.09 +1.140.0900.1930.0801509616397172026.7961_subunit2ofreplicationfactorC|DNAbindingproteinandATPasethatactsasaprocessivityfactorforDNApolymerasesdeltaandepsilonandloadsproliferatingcellnuclearantigen(PCNA)onDNA
197324___________ +1.03 +1.040.4400.6180.2761663617213172846.8405_pyrimidineprecursorbiosynthesisenzyme
*196790___________ +1.87 +2.000.0000.0020.0014063876154814156.8841_negativegrowthregulatoryprotein
41867____________ +1.04 +1.000.4880.2600.8901191112386119234.1867_
*19494____________ +1.47 +1.500.0020.0050.0051534322543229826.270__
196348___________ +1.27 +1.150.0030.0030.0311340817067153816.876__
*19260____________ +1.44 +1.650.0000.0010.0003501950279579496.1455_delta8-sphingolipiddesaturase
19250____________ +1.28 +1.230.0020.0030.0101512119401186026.1992_fattyacyltransferase
194125___________ +1.19 +1.100.0110.0110.0621411616831155436.2513_
191702___________ +1.13 +1.080.0180.0130.1531307114719141196.3043_GTP-bindingADP-ribosylationfactor
194699___________ +1.26 +1.100.0050.0040.0851339816883147136.3521_
194747___________ +1.18 +1.120.0100.0100.0621569418465175356.4017_mitochondrialprotoporphyrinogenoxidase
*192828___________ -1.23 -1.090.0130.0090.1534719238414432696.4489_alpha-tubulinfoldin,cofactorB
193479___________ +1.09 +1.030.4690.8850.2591892120669195746.4980_hypotheticalprotein
196297___________ +1.12 +1.170.0110.0370.0171667518688194496.5447_pseudouridinesynthase|rRNAmethyltransferase
1930_____________ -1.00 +1.001.0000.9950.9981707417003171556.5924_P-typeATPase,S.cerevisiaehomologisnecessaryforsensitivitytoakillertoxin(SMKtoxin)producedbyPichiaFarinosa
*191422___________ +1.38 +1.310.0010.0020.0023381346719443496.6392_
194089___________ -1.13 -1.060.2960.1530.6604805042600453426.6847_subunitofSCFubiquitinligasecomplex|regulatorofcellcycle
19889____________ +1.10 +1.120.0170.0210.0581801019821202256.7288_thiaminebiosynthesis|phosphomethylpyrimidinekinase
196988___________ +1.11 +1.100.0150.0150.0761254213895137576.7734_oligosaccharyltransferase|involvedinglycosylationintheERlumen
19936____________ +1.03 -1.010.3900.4180.3051511415622149126.8185_sphingomyelinphosphodiesterase
*197454___________ +1.15 +1.230.0120.0730.0132733131406335846.8614_TATA-bindingprotein-associated-factor|TFIIDandSAGAsubunit
195974___________ +1.13 +1.220.0060.0120.0191371115451166886.9063_requiredforstarvation-inducedautophagy
194549___________ +1.04 -1.020.4900.2690.8052258423406220976.95___
*195765___________ +1.39 +1.330.0040.0090.0111643722769218396.586__
191124___________ +1.05 -1.020.1760.0790.7672021621185197676.1199_phytanoyl-CoAdioxygenase(PhyH)
193151___________ +1.13 +1.060.0530.0350.2271320214895140276.1741_similartoplantdihydroflavonol4-reductase
*193951___________ -1.13 -1.360.0030.0280.0034923843656362056.2274_
194341___________ +1.04 +1.080.0760.0970.1121221812653131616.2798_cell-divisioncycle
194919___________ +1.30 +1.200.0060.0070.0331309416991156516.3298_transposase
195724___________ +1.09 +1.070.0460.0360.1621232313390131256.3795_
192223___________ +1.16 +1.120.0180.0240.0521568118199175266.4268_TNFreceptorassociatedfactor
192105___________ +1.19 +1.150.0500.0250.4581380016437159116.4756_zincfingerprotein
*194148___________ +1.32 +1.140.0080.0100.0462619534536298656.5231_hypotheticalprotein
192985___________ +1.02 +1.030.5400.4270.4961375013969141966.5704_hypotheticalprotein
195821___________ +1.02 +1.060.3100.2570.3421252612773132176.6157_conservedhypotheticalprotein
66634____________ +1.06 +1.090.1260.2860.0932354024912257196.6634_
19490____________ -1.01 -1.060.2680.6150.1492331223082219886.7081_peptideN-acetyltransferase
193838___________ +1.04 -1.030.6520.6380.4781119281165931090976.7533_translationelongationfactoreEF1beta|GDP/GTPexchangefactorforTef1p/Tef2p
195034___________ +1.13 +1.050.0530.0410.1822494528181261766.7975_conservedhypotheticalprotein
197337___________ +1.12 +1.050.0380.0210.3281297114468135916.8419_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*196778___________ +1.36 +1.330.0060.0110.0191556621102206516.8853_membrane-spanningCa-ATPase(P-type)
42343____________ +1.07 +1.010.5330.2880.9711204012932121374.2343_
*19361____________ -5.41 -5.410.0010.0020.0028574215856158386.285__mitochondrialcarnitineacetyltransferase
*196240___________ +1.39 +1.330.0020.0040.0081573221906209796.904__
*194793___________ +1.38 +1.310.0010.0040.0051776424600233276.1470_
191049___________ +1.45 +1.280.0010.0020.0061298518826165666.2005_
*191783___________ +1.88 +1.690.0010.0040.0041398726288236656.2531_oligomycinresistanceATP-dependentpermease|ABCtransporter
*194796___________ +1.32 +1.210.0030.0050.0192114327933256766.3056_
191504___________ +1.25 +1.150.0050.0100.0151388017319159126.3539_
195098___________ -1.28 -1.420.0010.0050.0032625420564184916.4033_endonucleaseIII-likeglycosylase
*195634___________ +1.76 +1.640.0000.0010.0013224856672527496.4503_ferricreductase
194517___________ +1.08 +1.060.1840.1190.3702662428754282196.4994_conservedhypotheticalmembraneprotein
*194676___________ -1.73 -1.820.0010.0040.0023609420862198686.5460_conservedhypotheticalprotein
19206____________ +1.22 +1.200.0060.0100.0201317416072157956.5939_
191547___________ +1.16 +1.070.0170.0150.0951621518733173936.6405_ThreePrimePhosphatase1|DNA3'phosphatase|similaritytomammalianpolynucleotidekinase3'-phosphatase
196710___________ +1.15 +1.120.0320.0380.0832246625923251216.6859_hypotheticalprotein
19875____________ -1.18 -1.180.0020.0060.0072697822833228226.7302_hypotheticalprotein
*197001___________ +1.45 +1.310.0020.0040.0081752425460229406.7746_
19948____________ +1.18 +1.070.0190.0140.1601306115414139466.8197_hypotheticalprotein
*195391___________ +1.39 +1.520.0000.0020.0012053628634311946.8627_snRNAbindingprotein
*195962___________ +1.41 +1.290.0010.0020.0102645637181341146.9075_highaffinityglucosetransportprotein
195844___________ +1.47 +1.270.0010.0020.0101306519230165886.114__
193535___________ +1.32 +1.210.0010.0040.0061566420607190316.605__
191353___________ +1.44 +1.340.0010.0020.0071467921200197246.1217_hypotheticalprotein
*193223___________ -4.34 -5.100.0000.0000.00038367188493752866.1763_ATPsynthasegammasubunit
*193774___________ +1.63 +1.490.0010.0010.0031565725484233746.2291_serine/threonineproteinphosphatasetype2A
194407___________ +1.27 +1.220.0070.0090.0341305216640158626.2821_
*195036___________ +1.68 +1.520.0010.0020.0041758629559267886.3313_conservedhypotheticalprotein
192559___________ -1.19 -1.060.1240.0760.3449577680527901976.3808_Fboxprotein,forubiquitin-dependentdegradation
*193536___________ +1.33 +1.300.0020.0070.0052108327982274216.4282_alphaN-acetylglucosaminetransferase
192375___________ +1.21 +1.290.3520.7570.1902220626865285506.4773_retrotransposongagprotein
193861___________ -1.09 -1.130.0530.0590.1073857035283341246.5250_
*192971___________ +1.28 +1.310.0010.0040.0032266228980297656.5718_conservedhypotheticalprotein
192492___________ +1.13 +1.150.0150.0320.0291423716124163936.6171_
*192966___________ -1.14 -1.080.0150.0150.0709134179850843726.6650_putativecarboxymethylenebutenolidase
*191477___________ -1.64 -1.970.0000.0020.0017986848576404966.7096_conservedhypotheticalprotein
196562___________ +1.09 +1.110.6820.7270.4711342314660149256.7550_ribonucleaseH
*195021___________ +1.33 +1.610.0040.0340.0051469119528236626.7988_pyruvatedehydrogenasecomplexproteinX
*197121___________ -1.41 -1.120.0360.0280.153112998802891009126.8432_hypotheticalprotein
196763___________ +1.06 +1.100.2740.4180.1893442536433379706.8866_
42597____________ +1.02 +1.030.3730.2880.4061209612358124244.2597_
196261___________ +1.33 +1.150.0030.0040.0301292017225148726.300__
191297___________ +1.24 +1.160.0040.0050.0221274415855147786.924__cytoplasmtovacuoletargeting
194646___________ +1.34 +1.230.0030.0040.0211451419404179206.1489_hypotheticalprotein
194461___________ +1.28 +1.090.0060.0050.0881250215959136806.2028_hypotheticalprotein
19804____________ +1.07 +1.040.1660.0840.5421603617209166206.2547_mitochondrialADP/ATPcarrierprotein|Grave'sdiseasecarrierprotein
193797___________ -1.03 -1.030.2220.1560.3561648816068160106.3070_
19856____________ +1.29 +1.200.0020.0030.0161486119161178236.3556_
193928___________ +1.25 +1.100.0070.0060.1231231415389135636.4049_
195647___________ -1.18 -1.230.0050.0150.0092470820954200386.4516_RNAhelicase
*194212___________ +3.06 +4.250.0000.0000.000379391159131614006.5009_multicopperferro-O2-oxidoreductaseinvolvedinhigh-affinityironuptake
*193744___________ +1.45 +1.410.0020.0050.0061834426552259566.5475_
195142___________ +1.09 +1.060.0870.0480.3771506016417159476.5956_dihydrofolatereductase
*191562___________ +1.47 +1.570.0020.0040.0051755625799275446.6419_hypotheticalprotein
*196725___________ -5.01 -6.390.0000.0010.00111063822073173056.6874_mitochondrialfumaratehydratase,3-primeend
196929___________ +1.08 +1.030.1340.0750.4121270613778130876.7315_conservedhypotheticalprotein
193023___________ +1.15 +1.050.0730.0320.6731465016883153216.7760_transcriptionfactor
*19962____________ +1.19 +1.200.0070.0150.0191583218806190316.8212_
*195407___________ +1.84 +2.360.0000.0020.0012039037476482016.8643_nucleolarsnRNPprotein
195947___________ +1.08 +1.140.0230.0380.0481418015377161196.9091_
19206____________ +1.26 +1.220.0030.0090.0071337216787163616.129__
*196891___________ +1.36 +1.290.0030.0070.0132039327754262476.632__
*193167___________ -1.22 -1.270.0170.0700.0212914023862228556.1237_
*192842___________ +1.87 +1.670.0010.0030.0041657730949276836.1777_
193848___________ +1.19 +1.110.0230.0150.1751246114865138866.2311_
194967___________ +1.07 +1.010.2140.1150.5311350814456137006.2838_proteinrequiredforcytochromecoxidaseactivity
*19702____________ +1.11 +1.160.0380.0600.0642563028325297016.3326_DNAhelicase
192640___________ +1.14 +1.130.0450.0920.0561603218289181916.3823_uracilphosphoribosyltransferase
19299____________ +1.24 +1.090.0580.0440.1841978524474215076.4294_carboxypeptidaseinvolvedincellwallbiogenesisandarchitecture
*195629___________ -1.31 -1.710.0020.0190.0027256755276425246.4788_ubiquinolcytochrome-creductasesubunit7
196550___________ -1.07 -1.130.0150.0940.0152351721938208616.5264_conservedhypotheticalprotein
191264___________ +1.07 +1.060.3880.2980.4181366414569144946.5731_ferricreductase
195768___________ -1.07 -1.080.1100.4250.0652994927964278566.6189_
*192954___________ -1.94 -2.640.0000.0010.00012139562440459766.6662_hypotheticalprotein
191462___________ +1.18 +1.160.0200.0220.0681338215731155706.7110_
196578___________ -1.38 -1.400.0300.0450.0622429417551174126.7566_inorganicphosphatetransporter,transmembraneprotein
195007___________ +1.09 -1.050.7690.5270.8232994232778285196.8001_
*197108___________ +1.25 +1.230.0160.0240.0427342092126902446.8445_D-ribulose-5-phosphate3-epimerase
196751___________ +1.04 +1.060.4290.8230.2352769528786294546.8880_tRNAmethyltransferase
42768f++3________ +1.08 +1.060.5640.3160.8891232113299130604.2768f
*193599___________ +1.53 +1.370.0010.0020.0062883344060395676.314__
19153____________ +1.28 +1.280.0090.0140.0291292816518165996.942__
*191133___________ +1.68 +1.440.0010.0030.0091842430908265416.1505_
193585___________ +1.41 +1.210.0020.0040.0151414719941171676.2043_conservedproteinrequiredforviabilityinbuddingyeast
19113____________ +1.33 +1.300.0030.0070.0101324817660172366.2563_
*191212___________ +1.79 +1.820.0000.0010.0025044890400917316.3084_
*192269___________ -2.65 -2.530.0000.0000.0004265241608611686336.3572_3-phosphoserinephosphatase
194674___________ +1.56 +1.250.0010.0030.0101411321962175786.4062_hypotheticalprotein
*194370___________ +1.83 +1.630.0000.0000.0004538483023740016.4535_conservedhypotheticalprotein
*193331___________ +2.76 +2.980.0000.0010.0011755748445523596.5023_
192701___________ +1.01 +1.000.9590.8340.8811726917494173076.5489_hypotheticalprotein
192029___________ +1.03 -1.010.4160.3090.4502533425978249886.5968_DNAreplicationnfactorC|leadingstrandelongationmismatchrepair(ATPase)
*191639___________ +1.49 +1.650.0020.0060.0051323419771217736.6433_
*195648___________ -1.69 -1.730.0000.0020.0025065129968292216.6888_
67329____________ +1.05 +1.120.2580.2660.2494247044529474716.7329_
*193038___________ +6.54 +7.840.0000.0000.000247441618061938846.7776_
19978____________ +1.30 +1.230.0080.0100.0391425718546174756.8227_transcriptionfactor
*195420___________ -2.09 -2.080.0000.0000.0007153434244344466.8657_
*195932___________ +1.57 +1.470.0000.0010.0002768743443407116.9105_conservedhypotheticalmembraneprotein
19160____________ +1.31 +1.270.0010.0030.0071268116592160966.145__hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194194___________ -1.04 -1.010.3220.2070.4752775726634275216.651__
191859___________ +1.26 +1.120.0080.0080.0591264215903142146.1255_hypotheticalprotein
197680___________ +1.03 +1.130.2860.2590.29895306985201079496.1797_
192504___________ +1.27 +1.180.0070.0090.0361268716108149216.2327_GTP-bindingproteininvolvedin40Sribosomebiogenesis
19460____________ +1.11 +1.070.0120.0110.0761259013997134376.2854_serine/threonineproteinkinaseofMAPkinasefamily|Requiredformating
*193334___________ -3.09 -2.430.0000.0000.0004811801558131982306.3341_ribosomalprotein
194880___________ +1.19 +1.160.5420.8200.3221247214835144186.3839_
*194477___________ -1.57 -1.170.0010.0010.0301958011250161672556.4310_aryl-alcoholdehydrogenase
19278____________ +1.13 +1.090.0270.0230.1141941321985211706.4807_neutralaminoacidtransportsystemprotein
193012___________ +1.09 +1.060.0780.0500.2711230813472131076.5277_
*191668___________ +1.30 +1.380.0010.0030.0012302029995316676.5743_hypotheticalprotein
*196594___________ +1.45 +1.470.0030.0080.0113536751109521466.6205_
194529___________ +1.01 +1.060.3650.6030.2192482824997264186.6675_conservedhypotheticalprotein
*191448___________ +2.17 +2.420.0000.0000.000536841165071301796.7125_adeninephosphoribosyltransferase
*196034___________ +3.43 +3.860.0000.0000.000366381257371414446.7578_beta-tubulin
*194993___________ +1.35 +1.690.0040.0230.0061576621346265896.8016_
*197095___________ +1.70 +1.840.0000.0010.0003802264734699276.8458_conservedhypotheticalmembraneprotein
*197546___________ +1.45 +1.780.0000.0030.0002284633041407106.8894_ATPdependentRNAhelicase
42857____________ +1.08 +1.040.0980.0600.3201189412874123524.2857_
19381____________ +1.19 +1.080.0070.0060.0721232714678132866.334__hypotheticalprotein
*191331___________ +1.73 +1.550.0020.0030.0081458525184226136.958__
*195066___________ +1.53 +1.420.0020.0030.0071407221474199226.1521_conservedhypotheticalprotein
*19367____________ +1.93 +1.950.0000.0000.0002487147916485126.2058_
*193369___________ +3.94 +3.940.0000.0000.0002015279452794626.2579_
194567___________ +1.28 +1.120.0040.0060.0191368117568152716.3099_hydroxyquinol1,2-dioxygenase
*192755___________ +1.68 +1.690.0000.0000.0002546642809429776.3587_proteasomesubunit
192363___________ +1.16 +1.400.1110.5220.0614439451466623256.4077_putativeheatshockprotein
*1957_____________ +1.54 +1.450.0010.0020.0021827628124264866.4549_subunitofGINScomplexrequiredforchromosomalDNAreplication
191968___________ +1.18 +1.170.0720.0510.2241791921066210176.5036_hypotheticalprotein
*196314___________ +1.31 +1.410.0010.0050.0031685422163236806.5507_16-kDaRNApolymerasesubunit(commontopolymerasesI,IIandIII)
*192043___________ +1.25 +1.430.0000.0020.0011762521985251186.5982_conservednucleotidebindingprotein
*191625___________ -2.49 -2.350.0000.0000.0008846935549376446.6447_oxidoreductase
195662___________ +1.05 +1.080.0830.0970.1271801318856193796.6902_vacuolarsegregationprotein
1948611__________ -1.06 +1.000.4650.2400.9503006728437301746.7350_NA
*193051___________ -1.53 -1.360.0000.0010.0033760824566276866.7788_conservedhypotheticalprotein
*193240___________ +1.09 +1.160.0090.0440.0132209024130256376.8240_3-ketosterolreductase
195433___________ -1.32 -1.240.0020.0040.0132349217852189046.8669_conservedhypotheticalprotein
195918___________ +1.10 +1.070.0250.0140.2931359214912145006.9119_hypotheticalprotein
*19723____________ +1.66 +1.730.0020.0080.0061501424960260016.6____
196244___________ +1.18 +1.090.0120.0120.0631959223097213476.672__
19244____________ +1.10 +1.100.1760.2870.1401607217756176276.1271_involvedinnitrogen-catabolitemetabolism
193456___________ +1.13 +1.070.0180.0180.0771668318857179296.1815_proteinserine/threoninekinaseinvolvedincellwall/polarity
*193895___________ +1.47 +1.350.0030.0050.0152996444132405996.2343_
191767___________ +1.01 +1.020.3540.1760.8151211212227124106.2870_ubiquitincarboxyl-terminalhydrolase
196493___________ +1.16 +1.080.0170.0180.0701235714328133586.3358_conservedhypotheticalprotein
19842____________ -1.09 -1.220.0510.6290.0266065455547497666.3853_hypotheticalprotein
193406___________ +1.08 +1.060.1920.1680.2562057122259217166.4325_highlyconservedhypotheticalprotein
*19609____________ +2.09 +1.790.0000.0010.0024651997134830916.4822_
*191358___________ -1.22 -1.410.0090.1390.0072217661819391571886.5290_transcriptionalactivatoroftheaastarvationresponse
193572___________ +1.08 +1.050.0440.0380.1411587517187166466.5757_hypotheticalprotein
196607___________ +1.14 +1.010.2800.1360.7383211236512325826.6219_NADH-ubiquinoneoxidoreductase|NADHdehydrogenasesubunit
*194540___________ +4.33 +3.250.0000.0000.00027786120222902766.6687_
*196874___________ +2.50 +2.390.0000.0010.0002690867271642176.7138_myb-liketranscriptionfactor
*196047___________ -8.77 -11.590.0000.0000.00044862351141386946.7591_mitochondrialtranslationelongationfactorTU
*197136___________ +1.48 +1.640.0020.0050.0051829427084300226.8032_
*197081___________ +2.49 +2.510.0000.0000.0002111352649529806.8472_tRNAsplicingprotein
197558___________ +1.11 +1.210.0100.0220.0231305214465158556.8907_
43057____________ +1.05 +1.060.0620.0380.2761316613779139144.3057_
*19462____________ +1.91 +2.490.0000.0010.0002477647397618036.352__mitochondrialmembraneexonucleaseinvolvedinpre-rRNAprocessing
191349___________ +1.26 +1.180.0050.0100.0171540619364182096.980__hypotheticalprotein
192868___________ -1.05 -1.090.0630.2780.0431180111216108656.1536_hypotheticalprotein
*191383___________ +1.44 +1.300.0010.0030.0071695024457219946.2081_hypotheticalprotein
193770___________ +1.17 +1.110.0130.0140.0651287515124143166.2597_
*191710___________ -1.60 -1.640.0010.0040.0044965430981303676.3117_mitochondrialNADH-ubiquinoneoxidoreductase
192785___________ -1.12 -1.180.0870.1710.0832948826293249296.3602_ATPsynthasedsubunit
*191759___________ +1.16 +1.160.0060.0140.0183191437055369446.4090_transcriptionalregulator
*195684___________ -5.13 -4.620.0000.0000.00039012176035845246.4562_mitochondrialribosomalproteinL14
*195858___________ -3.75 -4.140.0000.0000.00023833463497576376.5050_GAL4enhancerprotein
196328___________ +1.05 +1.010.3570.1960.6451643817249166676.5521_conservedhypotheticalprotein
196461___________ +1.06 +1.020.2210.1250.4891522816159155656.5998_cytochromeoxidase
*193443___________ +1.55 +1.670.0010.0020.0022201534224368506.6462_NAPDHdehydrogenase(oldyellowenzyme)
195676___________ +1.11 +1.100.0780.0930.1224113845520452656.6916_conservedhypotheticalprotein
*194847___________ +1.14 +1.180.0130.0340.0232749631413324876.7364_
*193063___________ +1.21 +1.110.0110.0110.0662998736272331946.7800_DNA-directedDNApolymeraseepsilon,subunitC
*193252___________ +1.37 +1.460.0010.0040.0022140929258313596.8252_transcriptionalactivatorforallantoinandGABAcatabolicgenes
*195446___________ -27.22 -20.150.0000.0000.000175179064347869496.8682_hypotheticalprotein
*195905___________ +1.48 +1.440.0090.0130.0341329019693191776.9132_nucleolarproteininvolvedinmating-typeregulation
195126___________ +1.00 -1.010.8530.8760.6332671026835264996.37___
194862___________ +1.38 +1.210.0010.0020.0051488420529180266.689__conservedhypotheticalprotein
196224___________ +1.32 +1.160.0030.0040.0321303517258150956.1289_conservedhypotheticalprotein
193726___________ +1.42 +1.260.0190.0140.1461310818668164636.1834_
19262____________ +1.34 +1.260.0020.0040.0121281517155160896.2357_
193370___________ +1.19 +1.180.0080.0170.0201301815487153036.2890_ubiquitin-specificprotease
*192524___________ -2.55 -2.200.0000.0010.0027797030618353736.3373_chaperoneinvolvedinproteinimportintomitochondria
192381___________ +1.29 +1.230.0020.0030.0101575120291193006.3867_
*192202___________ +1.17 +1.340.0030.0130.0061026701206071377326.4339_phosphoglyceratemutase
*191723___________ +5.29 +5.820.0000.0000.000271941439891581486.4837_conservedhypotheticalprotein
*193706___________ -1.21 -1.420.0030.0140.0043674230370258606.5304_
196342___________ +1.17 +1.150.0160.0240.0441296815112149756.5771_microfibrillar-associatedprotein1|associatedmicrofibrilprotein
196105___________ -1.13 +1.010.2210.1020.7588098171876819226.6237_
19811____________ +1.05 +1.010.6600.4020.8631817019040184276.6702_conservedhypotheticalprotein
*67151____________ -3.83 -3.400.0000.0000.00032188284039945796.7151_
196060___________ +1.16 +1.110.0180.0190.0761269814679141306.7604_ATP-bindingcassette(ABC)family,regulatoroftranslationalelongation
*197149___________ +1.61 +1.940.0010.0060.0031618126031314626.8049_conservedhypotheticalprotein
*197067___________ +1.82 +1.690.0000.0020.0012498945438422806.8486_requiredfornormalCLN1andCLN2G1cyclinexpression
*197572___________ +1.52 +1.460.0040.0080.0111396821199204536.8921_
43071____________ +1.16 +1.240.0110.0380.0171348815710166664.3071_
*19566____________ +1.58 +1.280.0120.0080.1871244319633159436.370__hypotheticalprotein
193868___________ +1.25 +1.230.0040.0080.0141315116439161426.1003_hypotheticalprotein
*193962___________ +1.66 +1.520.0000.0010.0021985133004300856.1552_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
193409___________ +1.24 +1.140.0110.0130.0541368216937155356.2099_
194129___________ +1.26 +1.230.0050.0080.0191286916245158676.2618_hypotheticalprotein
191158___________ -1.24 -1.240.0100.0170.0292543120550204876.3133_hypotheticalprotein
*192438___________ -1.40 -1.540.0010.0040.0033397224252220406.3616_conservedhypotheticalprotein
*192591___________ +1.53 +1.390.0010.0010.0051762826999244436.4107_DAPAaminotransferase
195700___________ +1.04 -1.070.2860.6810.1544017441763376796.4578_transcriptionalactivatorCTA2
*195609___________ +1.28 +1.220.0030.0070.0102757335341335076.5063_hypotheticalprotein
*192311___________ -1.92 -1.760.0000.0000.00016438085662934506.5539_ribosomalproteinL8B
19733____________ +1.06 +1.390.0630.9840.0303296333497844573716.6010_conservedhypotheticalprotein
*193664___________ -78.86 -82.080.0000.0000.000193812624578236146.6475_membraneheatshockprotein
193117___________ +1.32 +1.140.0090.0090.0671539220376176186.6927_
194831___________ -1.10 -1.060.1280.0670.4652077818912196236.7379_
*196442___________ +1.45 +1.320.0060.0080.0331417020537186986.7813_
193266___________ +1.18 +1.240.0010.0070.0031862621987230686.8266_hypotheticalprotein
195461___________ -1.13 +1.040.8350.6760.7271253911106351298256.8697_hypotheticalprotein
195892___________ +1.17 +1.130.0260.0260.0921276014906144506.9146_
191744___________ +1.25 +1.270.0050.0110.0141493418675189446.69___
*194867___________ +2.99 +2.690.0000.0020.0021698250735457056.706__
195757___________ +1.15 +1.090.0080.0080.0561284214789139466.1304_conservedhypotheticalprotein
*193142___________ +1.47 +1.200.0010.0010.0132258433161270086.1853_conservedhypotheticalprotein
*194635___________ +1.86 +2.060.0020.0060.0051342625015276866.2373_
19168____________ +1.14 +1.120.0300.0320.0901380715696154796.2904_exosomeexoribonucleaserelatedtoRNAprocessingandtransport
195050___________ +1.14 +1.100.0230.0210.1081234914126135436.3386_MitochondrialTranslationOptimization
*193683___________ +1.40 +1.290.0030.0050.0141923626912248946.3883_Znfinger-containingGTPase-ActivatingProteinforARF
*195504___________ +2.27 +1.750.0000.0000.0004184294988732246.4352_hypotheticalprotein
*195777___________ +1.18 +1.260.0160.0300.0342066124361260856.4849_involvedinpseudohyphalgrowth,resistancetoNaClandH2O2
*196155___________ +1.66 +1.500.0010.0020.0042345438897352026.5316_DNAligase
196357___________ -1.10 -1.090.0730.1010.1021170410687107786.5786_coiled-coilproteininvolvedinthespindle-assemblycheckpoint
*196091___________ +1.46 +1.040.0010.0000.15976097110875791406.6250_pHresponseregulator
*19827____________ -1.23 -1.450.0000.0060.0003361127248231656.6718_hypotheticalprotein
*196903___________ +1.26 +1.220.0020.0050.0102190527684266496.7167_RNApolymeraseIIIsubunit
*196073___________ +7.96 +5.460.0000.0000.000310992476371697436.7617_hemebindingprotein
197161___________ +1.10 +1.060.1200.0600.5023246835667343356.8061_betasubunitoftranslationinitiationfactoreIF-2
197055___________ +1.01 +1.010.2560.1560.4591302813158131896.8498_hypotheticalprotein
197589___________ +1.01 -1.070.3190.7160.1731893219094176646.8937_hypotheticalprotein
19619____________ +1.34 +1.270.0020.0050.0121262616877160496.386__hypotheticalprotein
191431___________ +1.19 +1.130.0110.0140.0461239014756140396.1025_allantoatepermease
196250___________ -1.16 -1.080.2770.3120.2395254245344486956.1567_
*197414___________ -1.26 -1.310.0010.0020.0023715529424283156.2110_
*62632____________ +2.09 +2.450.0000.0000.0002691256201658736.2632_
*194979___________ +1.59 +1.550.0040.0070.0141421822632220646.3147_
*19753____________ +1.73 +1.830.0000.0010.0002025834971370686.3632_mannosyltransferase
*195552___________ +2.32 +2.070.0000.0010.0012302853393475696.4122_hypotheticalprotein
*194760___________ +1.84 +1.950.0000.0020.0011931135517376676.4595_
*191238___________ +1.80 +1.530.0000.0010.0022029536586311046.5079_
*192680___________ +2.45 +2.180.0000.0010.0011724842289375506.5555_
*196264___________ -1.10 -1.170.0100.1910.0082582223458220316.6023_hypotheticalprotein
*193677___________ +1.31 +1.250.0010.0030.0113669448119459976.6488_involvedinautophagyandnutrientstarvation
193103___________ +1.11 +1.100.2300.1940.2891197251331651317356.6942_RNApolymeraseIIIlargesubunit
*196960___________ +2.72 +2.820.0000.0010.0011782048501502106.7392_
*196425___________ +1.57 +1.880.0020.0090.0051379221620258756.7828_
*193280___________ +1.46 +1.570.0010.0040.0042019929397317036.8280_hypotheticalprotein
197463___________ -1.10 -1.040.0830.0400.5051887817186181136.8713_
195875___________ +1.11 +1.050.0800.0530.2601315614618138046.9162_t-SNARE|integralmembraneproteinlocatedinendosome
195607___________ +1.49 +1.360.0020.0040.0091535622842208746.93___
195617___________ +1.36 +1.250.0010.0020.0061271017231158866.723__
192226___________ +1.32 +1.220.0020.0030.0131382918273168696.1319_hypotheticalprotein
*193802___________ +1.72 +1.500.0030.0060.0111271421893190646.1865_
192531___________ -1.20 +1.050.0950.0400.8815229043659549056.2388_cellsurfaceprotein
195742___________ +1.24 +1.220.0050.0130.0131256915624153426.2921_
*195126___________ +1.23 +1.120.0410.1010.0471796022165200676.3405_
19417____________ +1.20 +1.130.0080.0120.0331296415617146716.3898_membranetransporter,MitochondrialCarrierFamily
193505___________ +1.20 +1.140.3020.2710.3101189641428041352806.4365_putativetranscriptionfactor
*192998___________ +1.58 +1.530.0000.0010.0012968246843453966.4868_
*196168___________ +1.65 +1.900.0010.0030.0021851430594352636.5329_conservedhypotheticalprotein
*19997____________ +1.52 +1.430.0000.0010.0012292834954327986.5801_hypotheticalprotein
*19398____________ +1.45 +1.720.0000.0000.0003170146075544296.6266_hypotheticalprotein
*19518____________ +1.24 +1.310.0060.0290.008978911216791278766.6730_tRNA:m5C-methyltransferase
196916___________ -1.75 -1.580.0010.0020.0032846016242180196.7180_F1F0-ATPasecomplexassemblyprotein
196530___________ +1.17 +1.140.0080.0130.0281696219894193616.7630_conservedhypotheticalprotein
*197177___________ +1.79 +1.400.0100.0120.0481379624657192906.8077_karyopherin|nucleartransportfactor
*197350___________ -2.97 -2.950.0000.0000.0007916442666732687736.8510_highlychargedconservedproteinofunknownfunction
*197601___________ +1.12 +1.220.0040.1050.0032444427421297416.8949_conservedhypotheticalprotein
19121____________ +1.55 +1.290.0030.0040.0201278419789164826.406__subunitoftheArp2/3complex
*195865___________ +1.53 +1.440.0010.0020.0031722726423247376.1040_
191808___________ +1.29 +1.150.0050.0060.0371218115746140566.1582_hypotheticalprotein
191048___________ +1.29 +1.270.0050.0100.0161231415824156276.2130_conservedaryl-alcoholdehydrogenase
192627___________ +1.28 +1.180.0040.0070.0201310816803154296.2647_hypotheticalprotein
194312___________ +1.28 +1.200.0050.0080.0191359017458163276.3166_
194187___________ +1.36 +1.210.0030.0050.0151347418391162976.3644_mitochondrialoutermembraneproteininvolvedinmaintainingmitochondrialshape
*19747____________ +1.35 +1.340.0000.0010.0012323931391311446.4136_nuclearATPase
*194306___________ +1.13 +1.180.0140.0800.0153872243798457796.4611_conservedhypotheticalprotein
196013___________ +1.20 +1.160.0060.0100.0251418017002164496.5093_interactswithtopoisomerase1
*192340___________ +1.54 +1.850.0000.0000.0004011861831743786.5570_
196276___________ +1.12 +1.070.0210.0230.0741388215610148596.6035_conservedhypotheticalprotein
*19432____________ -1.52 -1.280.0000.0010.0084112327142320216.6501_conservedhypotheticalprotein
*195178___________ +1.69 +2.140.0000.0000.000716391207911531936.6958_cytochromeP450
193996___________ -1.00 +1.080.1940.6920.1002866428583309386.7409_glycosylphosphatidylinositol(GPI)synthesis
*196408___________ +1.40 +1.280.0090.0130.0341513821213193786.7845_
*195305___________ -2.08 -2.150.0010.0040.0059921047675461096.8294_conservedproteinreressedinhyphaldevelopment
*197478___________ -2.57 -2.300.0000.0000.0008365032535362956.8730_hexaprenylpyrophosphatesynthetase
193371___________ +1.23 +1.150.0080.0090.0511294615917148536.140__
195520___________ +1.17 +1.120.0130.0110.1011290015121144466.743__
191610___________ +1.18 +1.130.0080.0130.0261247214658141436.1339_hypotheticalprotein
193200___________ +1.25 +1.100.0100.0070.1241315816395144816.1883_matinglocusregulatoryprotein
194818___________ +1.23 +1.150.0130.0250.0291425817595163916.2401_hypotheticalprotein
193375___________ +1.11 +1.060.0980.0610.3051253013891132646.2937_
192184___________ +1.19 +1.120.0050.0060.0361594719045178326.3420_
192505___________ +1.15 +1.130.0100.0170.0301258014510142096.3910_hypotheticalprotein
*191798___________ +1.36 +1.460.0040.0080.0131563821272228696.4377_conservedhypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
191321___________ +1.08 +1.090.0340.0440.0751268613677138506.4882_
191580___________ +1.07 +1.140.0110.0230.0271621817359185436.5341_
196365___________ +1.01 -1.020.5310.2870.9771647216687161846.5817_phosphotyrosine-specificproteinphosphatase
19386____________ +1.16 +1.220.0060.0180.0131602618527195486.6278_AdoMet-homocysteinemethyltransferase
19533____________ +1.04 +1.050.1240.1110.2051307313637136906.6745_hypotheticalprotein
193297___________ -1.27 -1.360.0000.0030.0012351818579172586.7192_concervedhypotheticalprotein
196517___________ +1.01 -1.050.6010.6370.4211654516693158026.7644_
*1964031__________ -1.31 -1.740.0020.0190.0033953953027892267096.8088_NA
*197363___________ +1.33 +1.540.0060.0110.0181538920525237146.8523_glucansynthasesubunitinvolvedincellwallassembly
197614___________ +1.05 +1.060.1260.1000.2402416925313256536.8962_hypotheticalprotein
19625____________ +1.26 +1.280.0030.0060.0121261715888161586.422__
194697___________ +1.48 +1.290.0020.0030.0111388220609179656.1058_
195059___________ +1.18 +1.130.0190.0230.0581208414207136526.1607_
191077___________ +1.46 +1.300.0020.0040.0121428420882185226.2147_mitochondrialABCtransporter
191773___________ +1.28 +1.200.0030.0050.0131343917154161906.2661_
19268____________ +1.50 +1.440.0020.0050.0061431921484206726.3181_
19761____________ +1.29 +1.210.0020.0030.0101669621608201426.3661_hypotheticalprotein
*191690___________ +3.04 +2.820.0000.0000.0002622379723738836.4151_
*195701___________ +1.82 +1.830.0000.0010.0015225294920958016.4631_conservedhypotheticalprotein
196131___________ +1.05 -1.000.5840.3780.6771678217682167196.5112_3-ketosphinganinereductase
*192324___________ +1.44 +1.240.0010.0030.0072900541795359006.5584_ubiquitin(URM1)activatingenzyme
194942___________ +1.12 +1.080.0510.0360.2071264914159137116.6048_hypotheticalprotein
*19448____________ +2.65 +2.320.0000.0000.0012769473424643706.6517_
195165___________ +1.15 +1.100.0120.0170.0391611518503177626.6971_conservedhypotheticalprotein
*194009___________ +1.53 +1.380.0000.0010.0021770027130243556.7421_
196391___________ +1.08 +1.110.0490.0520.1131238413383137576.7863_hypotheticalprotein
195318___________ +1.39 +1.270.0040.0060.0221360618924173416.8308_
197490___________ +1.03 -1.010.5190.3430.6001839318875182116.8742_conservedhypotheticalprotein
192921___________ +1.21 +1.190.0080.0130.0261260515292149736.168__
19651____________ +1.31 +1.220.0040.0070.0191250916413152286.763__
19801____________ +1.47 +1.280.0030.0050.0131380620271176976.1354_
192827___________ +1.36 +1.220.0020.0030.0191407619074171556.1901_highlyconservedhypotheticalprotein,putativecytoskeletalcomponent
193950___________ +1.18 +1.130.0190.0180.0921415116754159596.2417_methionyl-tRNAsynthetase,mitochondrial
194488___________ +1.08 +1.070.1460.1480.1921262613589135436.2950_
191828___________ +1.25 +1.210.0040.0060.0181282615977155486.3435_involvedinbudsiteselection
196018___________ +1.18 +1.080.0100.0080.1091224514415132506.3923_
*193204___________ +1.75 +1.760.0000.0020.0012737447784480446.4395_hypotheticalprotein
194787___________ +1.24 +1.120.0090.0090.0551386017161155456.4897_DnaJ-likechaperone
191403___________ -1.11 -1.160.0110.0740.0122220220025191606.5356_calcium-bindingmitochondrialcarrier
196379___________ +1.09 +1.040.1100.0650.3551301014225134746.5831_hypotheticalprotein
195078___________ +1.19 +1.110.0980.0450.5982567230654284436.6298_hypotheticalprotein
19547____________ +1.10 +1.110.0360.0360.1051383415281153836.6758_
*193310___________ -1.27 -1.310.0250.1730.0205194040882397366.7205_hypotheticalprotein
196503___________ +1.16 +1.050.0450.0390.1421456916847153646.7657_hypotheticalprotein
*197202___________ +1.36 +1.180.0100.0080.1112063028088243006.8102_membraneproteinretentioninER
197375___________ -1.05 -1.010.4310.2740.5662292021809227226.8535_smallnuclearribonucleoprotein
197627___________ +1.01 +1.020.4160.2470.6161328413465134966.8975_conservedhypotheticalprotein
194863___________ +1.01 -1.020.6780.4180.8731184511966116036.442__
191592___________ +1.35 +1.230.0020.0040.0101291217444159216.1070_conservedhypotheticalprotein
194882___________ +1.29 +1.140.0050.0070.0251247816118142726.1624_
191272___________ +1.25 +1.160.0040.0060.0231298216243150276.2164_conservedhypotheticalprotein
191240___________ +1.26 +1.160.0050.0060.0381254915857145756.2677_
194119___________ +1.25 +1.130.0130.0120.0731261315794143136.3194_requiredforpexophagy
195219___________ +1.60 +1.300.0010.0020.0071493023946194166.3680_GTPaseactivatingprotein
191377___________ +1.21 +1.110.0130.0090.1771385616799153166.4163_dualspecificityinositol1,4,5-trisphosphate6-kinase|regulatorofarginine-responsivegenes
193551___________ +1.22 +1.110.0110.0150.0371305315905145196.4650_putativecytoskeletalprotein
*196229___________ -1.73 -1.790.0080.0170.0213150018170176416.5128_
191940___________ -1.09 -1.100.0620.2040.0502336521425212686.5599_mitochondrialproteininvolvedinubiquinonebiosynthesis
194167___________ -1.00 -1.020.9720.8580.9061277512735125566.6061_
196635___________ +1.34 +1.210.0060.0080.0271458619522176036.6532_hypootheticalprotein
66984____________ +1.20 +1.040.1040.0490.5491689620360175276.6984_
*194022___________ -2.47 -2.340.0000.0010.0015060020514215956.7435_membraneanchorinsuccinatedehydrogenasecomplex
194581___________ +1.11 +1.070.0490.0610.0911226413666130946.7880_mannosyltransferase
195328___________ -1.06 -1.060.1230.2390.1021248911821117636.8321_
197503___________ -1.02 -1.080.3900.5400.2552267122239210456.8755_chitindeacetylase
*193955___________ +1.64 +1.560.0000.0010.0022836946456441286.182__
194059___________ +1.23 +1.130.0040.0060.0271343916541152096.785__
1974_____________ +1.15 +1.100.0180.0160.0991250514420137036.1371_conservedhypotheticalprotein
*193931___________ -6.49 -7.920.0000.0010.00010677816444134886.1915_mitochondrialsuccinate-fumaratetransporter
195234___________ +1.33 +1.270.0030.0080.0071470019503187286.2435_
19193____________ +1.09 +1.150.0370.0780.0491277013916147056.2966_hypotheticalprotein
195206___________ +1.20 +1.120.0060.0090.0221596219123178716.3449_requiredforSnoRNAsoftheboxH/ACAQuantitativeaccumulation
195296___________ -1.28 -1.390.0010.0080.0022570620039184596.3938_conservedhypotheticalprotein
194044___________ +1.10 +1.000.0600.0260.7621710918763171276.4410_MuddledMeiosis
*195730___________ -1.35 -1.510.0010.0080.0025064637585336186.4909_3-polyprenyl-4-hydroxybenzoatedecarboxylase
192135___________ +1.21 +1.170.0160.0210.0541279415488150166.5370_
193879___________ +1.06 +1.090.0980.0990.1591193712654129646.5850_hypotheticalprotein
194392___________ +1.26 +1.200.0080.0090.0431538819400184796.6315_conservedhypotheticalprotein,mitochondrial
196665___________ +1.11 +1.200.0220.0490.0351777619804213916.6773_
*19335____________ +1.59 +1.400.0000.0010.0012355137358330776.7219_poorlyconservedhypotheticalprotein
195271___________ +1.14 +1.060.0280.0180.2161242414211131856.7670_
197214___________ +1.11 +1.160.0860.1850.0782895032113335906.8114_glucan1,3-beta-glucosidase
*197387___________ +1.68 +1.910.0010.0030.0011972633208377616.8547_ELongatorProtein|RNApolymeraseII-associatedHistoneacetyltransferase
*197643___________ -1.77 -1.920.0000.0000.0005589831560291466.8991_parahydroxybenzoate:polyprenyltransferase
19136____________ +1.41 +1.290.0510.1170.0561262917833162626.459__
191597___________ +1.29 +1.160.0030.0040.0311236015970143266.1085_hypotheticalprotein
193080___________ +1.09 +1.100.0710.0850.1171205013093132896.1637_
194730___________ +1.32 +1.220.0030.0050.0171494819734182586.2183_
193156___________ +1.34 +1.240.0030.0050.0211303417466161196.2692_
194072___________ +1.15 +1.090.0210.0180.1061260814478137396.3208_
*19685____________ -2.66 -2.580.0000.0000.0008650032572335626.3694_
195485___________ +1.10 +1.080.0250.0510.0402104723099226296.4179_involvedincheckpointcontrolandDNArepair|G2-specificcheckpointprotein
195492___________ +1.05 -1.030.4990.4780.3932441425525237236.4665_U1snRNPproteinrequiredforpre-mRNAsplicing
193905___________ +1.20 +1.100.0200.0210.0731273815312140596.5143_hypotheticalprotein
191850___________ +1.14 +1.130.0140.0180.0461266614465143166.5617_tyrosinephosphatase
194181___________ +1.05 +1.010.4170.2120.8791267713288127456.6075_subunitofsignalpeptidasecomplex
*196648___________ +2.07 +2.340.0010.0040.0021940640147454676.6544_
*196848___________ +1.58 +1.570.0000.0000.0003476654868545456.6997_vacuolarsortingprotein
*194035___________ -1.17 -1.620.0020.0790.0021695281445971048886.7448_GPIanchoredsurfaceprotein
194595___________ +1.09 +1.060.1190.0670.3901618017710170726.7894_hypotheticalmembraneprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
195348___________ +1.05 -1.020.1990.1390.3402398425276234896.8338_
*197517___________ +1.46 +1.430.0010.0040.0041437221012206016.8769_chitinase
193801___________ +1.24 +1.180.0240.0200.1201251115564147586.201__
193591___________ +1.19 +1.130.0120.0120.0721222814515138676.806__
191299___________ +1.35 +1.240.0030.0040.0171303917615161996.1388_proteasomeregulatoryparticlesubunit
*19554____________ +1.68 +1.770.0000.0010.0012071334752367646.1929_catalyzesoxidationofN-formyltyrosinetoN,N-bisformyldityrosineinsporewallformation
*194056___________ +2.19 +1.840.0000.0000.0003908285531718666.2451_GATA-familyDNAbindingproteins
*191108___________ +1.84 +1.950.0000.0000.0003112457218606416.2984_mayfunctioninDNArepair
*191111___________ +1.53 +1.630.0000.0010.00164124982301048416.3463_TFIIDandSAGAsubunit
*193765___________ +3.08 +3.170.0000.0000.0002261469680717976.3954_membraneproteininvolvedinbipolarbudding
*195587___________ -1.46 -1.410.0020.0040.0093544724215251506.4429_conservedhypotheticalprotein
*191066___________ +1.41 +1.370.0000.0010.0022015428366275586.4923_conservedhypotheticalprotein
*192151___________ -1.26 -1.340.0230.0500.0388468867198633626.5387_
*193129___________ -1.16 -1.250.0210.0540.0327377063737590816.5866_RUVB-likeprotein
*194351___________ -1.72 -1.130.0000.0000.047145988849371291846.6327_
*196680___________ -1.01 +1.110.0490.8620.0242854128394315486.6789_hypotheticalprotein
*19348____________ +1.34 +1.710.0010.0220.0011039861396361780436.7232_cellwallbeta-1,6glucansynthase
*195259___________ +1.21 +1.200.0100.0270.0183530042574424416.7683_hypotheticalprotein
*197228___________ +1.25 +1.280.0020.0100.0042629432843335976.8128_conservedhypotheticalprotein
*197399___________ +1.36 +1.740.0010.0070.0021662222554288446.8559_
197660___________ -1.05 +1.110.1100.5350.0602421623028269136.9008_suppressorofactinmutation
191570___________ +1.07 +1.130.2510.6930.1323879841346439536.480__
*191090___________ +1.75 +1.550.0010.0030.0021873732752289546.1102_hypotheticalprotein
*192616___________ +1.82 +1.620.0020.0050.0071452026360234606.1654_
196244___________ +1.48 +1.370.0010.0030.0041479321824202806.2196_
*193628___________ +2.73 +2.620.0010.0030.0031504941091393836.2711_hectdomainE3ubiquitin-proteinligase
191028___________ +1.13 +1.100.0150.0240.0391313814871144236.3223_transcriptionalelongationfactor
*196481___________ +1.32 +1.290.0100.0340.0152795036980359266.3713_GPI-anchoredaspartylprotease
*194502___________ +1.45 +1.300.0020.0040.0121592023088207146.4193_
192581___________ +1.08 +1.070.0790.0650.1891515616401161616.4682_putativedihydrokaempferol4-reductase
*19216____________ +1.54 +1.500.0000.0010.0012155833274322416.5157_conservedhypotheticalprotein
19326____________ -1.44 -1.350.0020.0040.0072569017794190256.5632_conservedhypotheticalprotein
*192175___________ -1.36 -1.240.0020.0020.0173645326867294256.6088_oxidoreductasesimilartomammalianApoptosisInducingFactor
*19668____________ +2.41 +2.210.0000.0010.0011650839704365406.6561_transcriptionfactortargetofSBF
196860___________ -1.03 +1.030.3880.2290.5973026229340312316.7009_phosphatidylinositolsynthase
*192093___________ +1.58 +1.710.0010.0030.002786761244331341526.7462_DNAreplicationfactorA|DNA-damagerepair
194609___________ +1.04 +1.010.2970.1440.7731197112499121126.7908_endo-1,3;1,4-beta-D-glucanase
*195365___________ +1.19 +1.320.0040.0220.0072402228536318146.8354_
*197534___________ +1.90 +1.910.0000.0010.0012145440679410526.8785_
19130____________ +1.19 +1.180.0040.0100.0091246914827147666.10___
1923181__________ +1.07 +1.120.0150.1120.0141252813427140536.503__NA
193956___________ +1.09 +1.060.0490.0810.0701249313561132706.1120_
194335___________ +1.00 +1.040.3830.9880.1991250812570129916.1676_
*196464___________ +1.56 +1.510.0010.0030.0022230734821336106.2212_
192712___________ -1.01 -1.020.7570.7490.5501183811664116156.2728_RNAhelicaseinvolvedinsnoRNAfunction
191728___________ +1.07 +1.040.1790.1170.3631214312987125836.3237_hypotheticalprotein
193091___________ +1.10 +1.050.1210.1280.1691319614562138596.3731_
192342___________ +1.07 +1.050.1670.2590.1421305514011136686.4210_similartomammaliansyntaxin5
192739___________ +1.06 +1.060.1130.1460.1351208412827128566.4695_
192419___________ +1.01 +1.020.8700.7570.7221270812834129806.5174_highlyconservedhypotheticalprotein
193971___________ +1.00 +1.020.9360.7830.8631201012036122296.5647_hypotheticalprotein
*193419___________ +2.28 +2.060.0000.0030.0014334198719894476.6106_mitochondrialmalatedehydrogenase
192774___________ +1.03 +1.030.3130.1700.6121235012661126636.6578_lipoicacidsynthase
191900___________ +1.12 +1.090.0910.1160.1221697419049185826.7020_TrimethylGuanosineSynthase
192078___________ +1.30 +1.230.0040.0100.0101462419045179446.7477_clathrin-coatprotein
194623___________ +1.15 +1.110.0170.0330.0341361315619151266.7922_hypotheticalprotein
197286___________ +1.01 +1.020.7400.5850.6491398014139141956.8367_subunitoftheregulatoryparticleoftheproteasome
196830___________ -1.11 -1.180.0210.0370.0431955217614166226.8801_enoylCoAhydratase
Cabgl98__________ -1.04 -1.050.2470.3350.193118261132311313Cabgl98
19229____________ +1.50 +1.350.0010.0030.0021448421673195376.216__
191652___________ +1.23 +1.190.0170.0290.0391610219744192106.828__
*19164____________ +1.48 +1.620.0010.0100.0021292919124209556.1404_
193515___________ +1.11 +1.090.1680.1970.1781739419339189856.1948_3-hydroxyanthranilicaciddioxygenase|biosynthesisofnicotinicacid
192154___________ -1.18 -1.100.3620.2340.4987444663244677866.2468_
*191097___________ +7.76 +5.690.0000.0010.00116396212716099324496.2999_
*19134____________ +1.66 +1.670.0030.0180.0052243537157373836.3480_hypotheticalprotein
194252___________ +1.06 +1.040.4200.6930.2451260413387130796.3972_predictedserine/threonineproteinkinase
*19307____________ +1.28 +1.410.0130.0810.0142733134852384356.4445_Ada/Gcn5proteincomplexmember
*192844___________ +1.79 +1.810.0000.0020.0011828632696331376.4939_
196184___________ +1.02 +1.000.3440.9520.1761526315564152726.5405_hypotheticalprotein
1983_____________ +1.30 +1.240.3880.4340.2954429157543549496.5882_C-terminusofdelta-9fattyaciddesaturase
195105___________ +1.09 +1.110.2630.3480.2041847620199204186.6345_transcriptionactivator
196696___________ -1.39 -1.290.0310.0460.0632287016455177676.6805_mitochondrialinnermembranetranslocase
194436___________ +1.02 +1.060.2420.3080.2001486415227156846.7248_glutathioneperoxidase
195246___________ +1.03 +1.030.4450.3290.4701334613684137246.7696_hypotheticalprotein
197243___________ +1.18 +1.240.0060.0270.0101587718768196616.8143_deoxycytidylatedeaminase
197414___________ -1.17 -1.160.0350.0450.0761885016076162776.8575_
197675___________ -1.11 -1.090.0180.0310.0401272111432117066.9023_mitochondrialribosomalproteinMRPL25
*193873___________ +1.18 +1.300.0070.0270.0113832545226498476.32___
195124___________ +1.25 +1.240.0010.0040.0041863623333231906.524__
19194____________ +1.19 +1.200.0050.0100.0181326315738158966.1143_
1969_____________ +1.06 +1.000.2050.0950.7441383514731138566.1692_hypotheticalprotein
*193600___________ +1.36 +1.420.0010.0030.0062067628202292856.2227_hypotheticalprotein
193633___________ +1.58 +1.380.0020.0040.0131357821416186716.2748_transthyretinprecursor(Prealbumin)
*194332___________ +1.52 +1.350.0020.0040.0101545423429208166.3254_
19848____________ +1.20 +1.080.0220.0150.1611318515762142446.3746_hypotheticalprotein
*194412___________ -1.36 -1.280.0030.0060.0132974321818231956.4227_
194657___________ +1.26 +1.240.0060.0150.0151325816739163906.4708_NuclearEnvelopeMorphology
*192404___________ +1.20 +1.280.0110.0490.0144031848442515386.5188_
193984___________ +1.26 +1.160.0070.0120.0251312516558152686.5660_
*192903___________ +2.21 +2.340.0000.0000.0003779783496883686.6119_conservedhypotheticalprotein
*192761___________ -1.13 -1.130.0300.0540.0522877425353255606.6591_
*191885___________ +1.32 +1.460.0010.0070.0023363244257491306.7036_
192066___________ -1.01 -1.040.4860.4800.3761743617342167796.7489_conservedhypotheticalmembraneprotein
197010___________ +1.46 +1.500.0010.0030.0051473521484220696.7936_conservedmembraneproteinwithBTB/POZdomain
*197300___________ +1.34 +1.550.0010.0040.0021902225484294106.8381_hypotheticalprotein
*196814___________ -1.85 -1.830.0020.0040.0066739403643003677446.8816_
Cafen1___________ +1.00 -1.050.3530.9610.181118311187311289Cafen1_
*194145___________ +1.36 +1.220.0060.0080.0321332818129163266.236__
*191208___________ +3.66 +3.320.0000.0010.0011826266794606846.841__

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*194780___________ -1.58 -1.330.0000.0010.004155623986031174166.1422_multidrugtransporter
*191914___________ +1.31 +1.240.0010.0030.0081966325663243566.1965_hypotheticalprotein
194065___________ +1.21 +1.070.0210.0170.1171273015404135976.2483_hypotheticalprotein
191247___________ +1.10 +1.070.1030.0650.3111288214118138266.3012_
194265___________ +1.16 +1.150.0080.0210.0181990823159228026.3492_UDP-n-acetylglucosaminepyrophosphorylase
194348___________ +1.27 +1.250.0090.0120.0341395817710174166.3992_transcriptionalregulation
*195518___________ +2.33 +2.000.0000.0010.0011682439197337006.4460_hypotheticalprotein
195853___________ +1.03 +1.080.1080.2570.0832070121356223286.4955_
*196205___________ +1.16 +1.140.0070.0130.0222800532391320556.5419_conservedhypotheticalprotein
*192249___________ -1.54 -1.540.0020.0050.0053023719662196556.5897_neutralzincmetallopeptidase
192001___________ -1.00 +1.030.8830.8660.6832624626141269066.6359_conservedhypotheticalprotein
*194117___________ +1.23 +1.300.0020.0080.0032996836817388616.6819_hypotheticalprotein
194448___________ -1.14 -1.160.3180.2580.3555717050301492906.7261_leucine-richrepeatprotein
*195232___________ +1.67 +1.590.0000.0020.0012373139564378296.7710_conservedhypotheticalprotein
197257___________ +1.14 +1.080.0410.0290.1831275414557137196.8156_
*197433___________ +2.13 +2.180.0010.0040.0031781437883388216.8589_
196001___________ +1.06 +1.010.2540.1170.8511251213219126056.9036_secretedaspartylproteinase
194080___________ +1.19 +1.220.0110.0370.0171384416477169416.49___
195182___________ +1.21 +1.220.0040.0120.0091229714868149546.546__DNA-directedDNApolymerasedelta,catalytic125KDsubunit
191804___________ +1.05 +1.030.2520.2060.3131294613579133936.1161_putativemitochondrialtransporter
194697___________ +1.01 -1.010.5090.2730.9281325213368130906.1710_
191391___________ +1.10 +1.010.1380.0620.6961294814235130796.2243_dynactinsubunitP25
194219___________ -1.01 -1.010.9470.7980.8841169411562115686.2763_
192859___________ +1.02 +1.010.6140.4010.6971252712839126346.3270_
193458___________ +1.03 +1.020.5870.4200.5901244212802127116.3761_
*191283___________ +1.26 +1.250.0110.0330.0191879823640234086.4241_
*19575____________ +1.23 +1.320.0090.0510.0111906023504252086.4724_
194284___________ -1.01 -1.010.6730.4050.9291195011884118846.5202_pombecyclinChomologue
196139___________ -1.01 -1.020.7560.9030.5061230612182120256.5675_ferricreductase
192890___________ -1.05 -1.050.1490.0950.3461336712780127346.6132_conservedhypotheticalprotein,putativeUDP-galactosetransporter
194241___________ -1.03 -1.050.1840.1950.2051274412376121736.6604_hypotheticalprotein
191871___________ +1.22 +1.230.0100.0400.0151347016378165166.7050_
193809___________ -1.01 -1.040.6600.9580.4081208111908115926.7503_
197023___________ +1.06 +1.000.4180.2160.8291622417124162996.7949_PWWPdomainprotein
197313___________ -1.04 -1.040.4520.3760.4201225211827118186.8394_sulfitesensitivityprotein
196802___________ -1.06 -1.050.1710.2050.1781175611064111456.8829_conservedhypotheticalprotein
Casfl1___________ -1.05 -1.040.1460.3580.098117941126911320Casfl1_
*192467___________ +1.51 +1.410.0010.0030.0021470622191207126.251__
*191190___________ -1.73 -1.680.0030.0050.0138506249157507136.860__
19120____________ +1.15 +1.170.0050.0140.0121324615237154566.1441_
191954___________ +1.25 +1.210.0130.0450.0181767822021213316.1980_
*193681___________ +1.48 +1.400.0030.0110.0081571023303219616.2498_karyopherin-betainvolvedinnuclearimport
193229___________ +1.07 +1.190.0130.0310.0261378714756163556.3028_hypotheticalprotein
193965___________ +1.21 +1.170.0060.0170.0131255215175147386.3506_hypotheticalprotein
192941___________ +1.20 +1.090.0870.0570.2691282315328139406.4005_cellwallglucanase
193177___________ -1.04 +1.040.4940.3630.5064603944070478636.4474_DRAPdeaminase|riboflavinbiosynthesis
192465___________ +1.13 +1.090.0360.0490.0731261414244137806.4969_
196282___________ +1.03 +1.040.3620.3900.2901261813018131756.5432_
194930___________ +1.13 +1.050.4170.4480.3182308426063242866.5910_signalpeptidasesubunit
191411___________ +1.22 +1.170.0080.0230.0161502618260176126.6380_CytochromeP450
194101___________ -1.06 -1.100.0360.1070.0391201111337109266.6835_hypotheticalprotein
*19903____________ -1.35 -1.480.0140.0320.0275371433966283624876.7274_phosphoglyceratemutase
*196977___________ +1.64 +1.780.0000.0030.0011909331322339956.7723_glycosylphosphatidylinositolsynthesis|participatesinsynthesisofN-acetylglucoaminylphosphatidylinositol,thefirstintermediateinsynthesisofglycosylphosphatidylinositol(GPI)anchors
197272___________ -1.04 -1.050.3370.5630.2051154611053110106.8172_hypotheticalprotein
197443___________ +1.03 -1.010.5770.7190.3712341024118230656.8603_hypotheticalprotein
195986___________ -1.04 -1.030.1380.0700.5131604615450156106.9051_involvedinthiaminebiosynthesispathwayandDNArepair
1959_____________ +1.14 +1.210.0580.0900.0821781320379215406.73___
19867____________ +1.28 +1.210.0030.0040.0171268716303153156.567__
19147____________ +1.29 +1.220.0020.0040.0091334017154162726.1179_serine-threonineproteinkinase,PKAsuppressor
19706____________ +1.23 +1.310.0060.0190.0101796222037235196.1726_
191488___________ +1.34 +1.230.0040.0060.0291391418681170486.2260_hypotheticalprotein
195742___________ +1.18 +1.080.0260.0220.1211302615320140676.2783_
*193616___________ +1.46 +1.310.0020.0040.0091651424138216696.3286_farnesyl-diphosphatefarnesyltransferase|squalenesynthetase
*194362___________ -1.21 -1.160.0210.0280.0553108025704268846.3776_40kDaputativemembrane-spanningATPase
*191832___________ +1.96 +1.850.0000.0010.0011635631990303396.4254_putativepyridoxinetransporter
192120___________ +1.21 +1.140.0090.0130.0311231014899140426.4741_hypotheticalprotein
194811___________ -1.02 -1.030.4690.9120.2571491214652144316.5216_
19592____________ +1.18 +1.080.0270.0220.1301275415106137906.5689_
195833___________ -1.03 -1.080.2790.7010.1482244621843207486.6145_ubiquitinfusiondegradationprotein
*194225___________ +1.25 +1.410.0050.0170.0093083238433434066.6619_
*19504____________ +1.20 +1.240.0300.1080.0316609779198816756.7067_vacuolartargeting,actin-relatedprotein
193823___________ +1.24 +1.210.0110.0180.0301374216980166476.7519_
*197036___________ +1.18 +1.080.0060.0100.0222424828568262246.7962_involvedingrowthregulation
*197325___________ -2.33 -2.190.0020.0050.0074128817708188856.8406_innermitochondrialmembraneprotein
196789___________ -1.05 -1.020.5830.5930.4232002719149195436.8842_spindlepolebodyprotein
41875____________ +1.01 -1.060.2870.8100.1461179811938110864.1875_
19720____________ +1.17 +1.200.0030.0060.0111525817886183436.271__
196349___________ +1.48 +1.310.0010.0020.0081380020446180286.877__
*192636___________ +1.33 +1.540.0000.0020.0003904851973601546.1457_conservedhypotheticalprotein
19248____________ +1.50 +1.280.0030.0050.0151427221350182976.1993_
*194125___________ +1.38 +1.160.0030.0040.0271693423329197036.2514_transcriptioninitiationfactorTFIIIA
194526___________ -1.11 -1.110.0930.0730.2142073818654187316.3045_plasmamembraneheatshockprotein
19635____________ +1.19 +1.060.0870.0360.9351371416301145376.3522_hypotheticalprotein
194748___________ +1.27 +1.170.0070.0080.0461253515859146866.4018_U2snRNA-associatedprotein
192829___________ -1.02 -1.040.3490.8380.1831889018453181286.4490_conservedhypotheticalprotein
193477___________ +1.27 +1.260.0270.0540.0441467218668184496.4982_tRNApseudouridinesynthase
196298___________ +1.23 +1.210.0080.0190.0191552819143188466.5448_ATPdependentRNAhelicaseinvolvedinthematurationof25SribosomalRNA
1931_____________ +1.33 +1.160.0020.0030.0201507320105175196.5925_potentialcellwallprotein|memberofagroupofC.albicansorfsthatareweaklysimilartoScCIS3/PIR3/PIR1�orf6.5925
191424___________ +1.18 +1.200.1580.2280.1453497141227419046.6393_conervedhypotheticalprotein
*194088___________ -1.18 -1.150.0170.0340.0346381054280553106.6848_hydroxyacylglutathionehydrolase
*19886____________ +1.91 +1.520.0000.0010.0032270643413345386.7289_
196989___________ +1.23 +1.080.0140.0090.2641276715714138356.7735_putativesplicingfactor|RNA-bindingdomain
19937____________ +1.09 +1.030.1320.0650.5291262513767130306.8186_hypotheticalprotein
197455___________ +1.28 +1.110.0050.0060.0441473618916163136.8615_hypotheticalprotein
195973___________ +1.02 +1.030.5650.3620.6691207812284124516.9064_mitochondrialprohibitin
194548___________ +1.22 +1.090.0230.0290.0651599419440173706.96___necessaryforstructuralstabilityofL-AdsRNA-containingparticles
194398___________ +1.09 +1.080.0270.0630.0391203413118130226.587__conservedhypotheticalprotein
1911242__________ +1.21 +1.160.0380.0630.0621929623397223846.1200_NA
193152___________ +1.14 +1.040.0750.0340.6041261514369131466.1742_copper-containingamineoxidase
193952___________ +1.08 +1.030.1910.1140.4221437815499148456.2276_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194342___________ +1.05 +1.040.2570.2370.2771216612808126416.2799_conservedhypotheticalprotein
194919___________ +1.02 +1.030.8120.7510.6281272612950130626.3299_
195723___________ +1.03 -1.000.6270.5740.4861309813474130906.3796_acyl-coenzymeAoxidase
192616___________ +1.04 +1.040.2900.2050.3971289913446134206.4269_
192104___________ +1.00 -1.030.9970.9640.9601196512004116286.4757_molecularchaperone|maybeinvolvedinassembly/maturationofmitochondrialiron-sulfurproteins
194146___________ +1.04 +1.010.4920.3130.6091203812463121216.5233_
192984___________ -1.06 -1.070.0670.1250.0761277212064119896.5705_mitochondrialthreonyltRNAsynthetase
195820___________ -1.00 -1.010.8520.8960.6261207012056119436.6158_
*195801___________ +1.36 +1.240.0080.0200.0171543420951191006.6635_smallsubunitofribonucleotidereductase
*19489____________ -1.63 -1.740.0010.0030.0013137519274180306.7082_putativesterol-bindingprotein
193839___________ +1.01 +1.070.2080.4700.1271324013341141936.7534_secretoryaspartylproteinase
195033___________ -1.07 -1.080.0750.1490.0771190211080110376.7976_proteininvolvedinprotein-vacuolartargeting
197339___________ -1.02 -1.040.3050.6450.1701227812044117736.8420_beta-glucosidase2precursor
196777___________ -1.05 -1.090.0640.2260.0491211511509111466.8854_hypotheticalprotein
42400____________ -1.05 -1.090.0650.3580.0401174611137107934.2400_
1935_____________ +1.56 +1.400.0010.0030.0041354021181189816.286__
*193192___________ +1.49 +1.610.0050.0110.0151698925323273726.905__
*1967_____________ +1.67 +1.660.0010.0060.0021965932742326416.1472_hypotheticalprotein
*191051___________ +3.50 +3.380.0000.0010.0012067272309699716.2007_histone2A
*192751___________ +1.64 +1.610.0010.0030.0021462323982235636.2533_
194798___________ +1.05 +1.080.7980.9110.5532238423431241206.3057_membraneproteinwithweaksimilaritytomyosins
191502___________ +1.19 +1.180.0060.0140.0141255614919148796.3540_
195100___________ +1.16 +1.090.7980.6590.6752731331765296896.4035_ATP-dependenttransporter
*195635___________ -5.19 -5.880.0000.0000.00020291339082344886.4504_glycosyl-phosphatidylinositolprotein|similartoRBT5
194515___________ +1.28 +1.280.0040.0120.0091496419210191806.4996_poptentialcellwallproteinofthePIRfamily
194675___________ +1.26 +1.210.1800.1010.4581286816216155726.5461_conservedhypotheticalprotein
19207____________ +1.03 +1.040.3570.4560.2521251012941130246.5941_
191548___________ -1.02 -1.080.1770.4820.1042018319693186546.6406_U4/U6.U5snRNPassociatedprotein|RNAbindingzincfingerprotein(putative)
196712___________ +1.27 +1.270.0840.2040.0713144239822399276.6860_
19874____________ -1.00 -1.000.7730.5070.9321939219296193416.7303_conservedhypotheticalprotein
*197002___________ +6.68 +11.780.0000.0010.00013519903731593176.7748_hypotheticalprotein
19949____________ +1.04 +1.070.2030.2360.1981263413196134746.8199_
*195392___________ +4.30 +5.340.0000.0000.0001504964663803806.8628_conservedhypotheticalprotein
195961___________ -1.00 -1.320.1370.5250.0753762537599285446.9076_ankyrinrepeatproteinthatinteractswiththe19Sregulatoryparticleofthe26Sproteasome
192115___________ -1.08 -1.070.1440.2640.1163528632566328536.117__
1936_____________ +1.29 +1.160.0030.0040.0191235515883143756.608__putativeConservedOligomericGolgicomplex8
*191656___________ +1.71 +1.690.0000.0020.0012064835348349606.1219_conservedhypotheticalprotein
*193221___________ +1.53 +1.480.0000.0010.0013088047120457616.1765_carbamoylphosphatesynthetaselargesubunit,argininebiosynthesis
193775___________ +1.41 +1.200.0020.0050.0111450020436173856.2292_
*194406___________ -1.30 -1.280.0050.0100.0154143131969324036.2822_Ngg1p-interactionfactor
*195037___________ +1.73 +1.580.0010.0020.0041735530049274166.3314_conservedhypotheticalprotein
192560___________ -1.03 -1.040.3710.8090.1982722726421261676.3809_
*193537___________ +1.86 +1.790.0010.0030.0021328024669237726.4283_conservedhypotheticalprotein
*195615___________ +1.45 +1.300.0020.0040.0061666824109216766.4774_
193862___________ +1.01 +1.060.5510.7910.3333562835828378396.5252_requiredforaminoacidpermeasetransport
192970___________ +1.01 -1.040.3470.7650.1862005420203192606.5719_
192492___________ +1.09 +1.080.0630.0640.1321253813611135206.6172_
192965___________ -1.08 -1.050.2640.1540.4984691643589445646.6651_pump-drivingATPase
*191476___________ -1.40 -1.600.0030.0090.0104084229102255336.7097_activatorofIME1|meiosis|methyltransferase(putative)
196563___________ +1.21 +1.170.0080.0140.0241392416870162406.7551_conservedhypotheticalprotein
*195020___________ +1.72 +2.070.0000.0030.0011905032717394886.7989_conservedhypotheticalprotein
197121___________ +1.04 +1.020.2220.1580.3511628716934166346.8431_
*196763___________ +1.21 +1.510.0140.0600.0171647311985792489396.8870_
42612____________ +1.04 +1.010.3800.1930.8121199812479120974.2612_
*196260___________ +1.99 +1.580.0010.0020.0062080941342329456.302__
191759___________ +1.34 +1.190.0040.0050.0201307917542155816.926__
*194643___________ +1.76 +1.380.0020.0030.0141327023341182996.1491_
194463___________ +1.34 +1.240.0040.0070.0181282617181159016.2029_
*19802____________ +3.05 +2.520.0000.0000.0012735083457689376.2548_
*196965___________ -1.48 -1.430.0010.0040.0044129627819289016.3071_
192457___________ +1.18 +1.090.0100.0100.0691489917652162436.3558_hypotheticalprotein
193926___________ +1.27 +1.170.3190.1530.8441338316939156156.4050_ribonucleasefromtheT2family
195648___________ -1.12 +1.010.2710.1260.8583715433306373646.4517_putativenuclearexportfactor
194210___________ +1.02 +1.020.4550.2360.9001970720134200136.5011_epoxidehydrolase
*193746___________ +5.57 +5.920.0000.0000.000329581835241952496.5476_oligopeptidetransporterprotein
195141___________ +1.21 +1.060.0190.0110.3041210814689128856.5957_hypotheticalprotein
*191563___________ +1.69 +1.770.0000.0010.0002545242923449576.6420_membraneproteininvolvedincellwallbiogenesisandarchitecture|calcofluorsensitivity
196726___________ +1.01 +1.010.9430.7560.9983957639940401006.6875_weaksimtoSPT2transcriptionalsilencer
*196930___________ +1.80 +1.800.0000.0010.0012276441002409466.7316_hypotheticalprotein
193023___________ +1.15 +1.080.0270.0210.1451392815955150056.7762_
*19964____________ +1.39 +1.300.0120.0160.0401337218530173696.8214_
*195408___________ +2.36 +2.570.0000.0000.0002171051318558006.8644_proteinkinase
195947___________ +1.09 +1.040.1130.0700.3281199613041124546.9092_
19206____________ +1.10 +1.110.0710.1250.0821239213671137276.130__
192740___________ +1.24 +1.200.0060.0130.0171225215182147626.635__
*193171___________ -4.66 -5.460.0010.0030.0029558020529174906.1238_
193288___________ +1.21 +1.140.0180.0530.0261564118899178936.1778_conservedhypotheticalprotein
193851___________ +1.13 +1.130.0240.0300.0671314814811148276.2312_hypotheticalprotein
194966___________ +1.02 +1.040.3330.4560.2291176212004122736.2839_probablemitochondrialcarrierprotein
19703____________ +1.01 -1.020.9840.9840.8781586416046155596.3327_2',3'-cyclicnucleotide3'-phosphodiesterase
192639___________ -1.03 +1.020.4470.8560.2451381713407140856.3824_mitochondrialribosomallargesubunitproteinYmL20
19298____________ -1.16 -1.240.0040.0220.0072425020938196086.4295_hypotheticalprotein
195630___________ +1.09 +1.040.1700.1390.2611370814977143176.4789_ATPadenylyltransferaseII
196550___________ +1.01 -1.010.9210.7330.8891223612302121556.5265_
191265___________ -1.00 -1.020.8300.8440.6101211512055118716.5732_targetingcomplex(TRAPP)componentinvolvedinERtoGolgimembranetraffic
195768___________ -1.01 -1.000.9130.7390.8441290612779128466.6190_nuclearprotein
192953___________ -1.10 -1.090.0540.0740.0881432413034131696.6663_mitochondrialoutermembraneimportreceptorsubunit
*191461___________ +5.87 +6.770.0000.0000.0001381981140935296.7112_conservedhypotheticalprotein
196579___________ -1.04 -1.010.7110.4420.9191198811518118996.7567_hypotheticalprotein
*195006___________ -1.09 -1.590.0370.1280.0363931036036246906.8003_H-proteinsubunitofglycinecleavagesystem
197107___________ +1.27 +1.160.1040.1880.0983784248118440496.8446_conservedhypotheticalprotein
*196749___________ +1.36 +1.450.0020.0120.0031896725793274286.8881_
42795f++1________ -1.04 -1.070.2240.8860.1101278612312119754.2795f
*193599___________ +1.37 +1.240.0010.0020.0031870425552231466.318__
192309___________ +1.30 +1.320.0020.0070.0041326017295175696.943__
61508____________ +1.11 +1.140.0140.0300.0281255113882143616.1508_
*193586___________ +1.35 +1.320.0090.0580.0112088928268276086.2044_
19113____________ +1.17 +1.090.5090.3810.5061210414205132516.2562_
63086____________ +1.06 +1.040.1690.1970.1801225912954127586.3086_
*192268___________ -2.35 -2.310.0000.0010.00210384844140449046.3573_Ca2+/calmodulin-dependentserine/threonineproteinkinase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194673___________ +1.18 +1.190.0180.0410.0301293215261153526.4063_hypotheticalprotein
*194371___________ -1.83 -2.190.0020.0040.0063499101912301600856.4536_transaldolase
193330___________ +1.15 +1.140.0210.0450.0361418516313162356.5024_GTP-bindingprotein
192703___________ +1.18 +1.160.5050.2730.8671447817148168616.5490_
*192032___________ +1.82 +1.800.0010.0030.0032997654558540146.5971_hypotheticalprotein
*191638___________ +2.63 +2.890.0000.0010.0002160056902624816.6434_componentofCOPIIcoatofER-golgivesicles,GTPaseactivatingprotein
*195649___________ -2.82 -3.200.0000.0000.0008144028830254836.6889_
*196944___________ -1.31 -1.380.0180.0240.0534801436774348976.7331_
*193040___________ +1.92 +2.090.0000.0050.0014396884432918066.7777_alcoholacyltransferase
*19979____________ +1.44 +1.680.0020.0170.0021593422953268296.8228_fatty-acyl-CoAsynthase,betachain
195422___________ +1.16 +1.140.0540.2270.0401797020896204886.8658_hypotheticalprotein
195931___________ +1.15 +1.160.0080.0230.0151422316297165266.9106_involvedinsteroluptakeanddistributionintotheplasmamembrane
19160____________ +1.27 +1.260.0020.0030.0101251815877157566.146__
196259___________ +1.37 +1.190.0020.0030.0131270417459150676.654__
191859___________ +1.43 +1.200.0030.0040.0231287418381154526.1254_
193387___________ +1.02 +1.030.5440.6490.3613735337944385976.1800_reversetranscriptase
*192506___________ +1.52 +1.370.0020.0040.0081398521319191086.2329_
19459____________ +1.07 +1.080.5760.3610.7032614628085281736.2855_ATP-dependentpermease|membranetransporterABCsuperfamily
*193335___________ -3.07 -2.750.0000.0000.00023262775817846776.3342_hypotheticalprotein
194881___________ -1.06 +1.030.2940.1820.4802467723354255206.3840_hypotheticalprotein
*194476___________ +1.27 +1.300.0000.0020.0011959424819254176.4311_aryl-alcoholdehydrogenase
19279____________ +1.11 +1.060.0990.0600.3251438015956151976.4808_d-tyr-tRNA(tyr)deacylase
1930101__________ +1.09 +1.000.9110.9300.7092842630947285016.5278_NA
191669___________ -1.14 -1.070.0980.0540.3844032935496377896.5744_ATPdependentmetalloprotease
196595___________ +1.05 +1.050.6370.6240.4681241212984130016.6207_putativetransporterorflippasethattranslocatesLCBsfromthecytoplasmicsidetowardtheextracytoplasmicsideofthemembrane
194529___________ +1.01 -1.000.8900.6570.9701849018747184226.6676_
191447___________ +1.32 +1.400.0010.0050.0041652221864231416.7126_
196035___________ +1.04 +1.000.3680.1900.7581359514115136526.7579_ubiquinoneoxidoreductase
*194991___________ +1.13 +1.170.0110.0240.0232083623628244396.8017_
197094___________ +1.12 +1.080.0170.0100.2641269014179136796.8459_glucosesensorortransporterprotein
*197547___________ +1.41 +1.400.0020.0050.0102023928616283256.8895_phosphatidylinositol(3)-phosphatebindingprotein
42858f___________ -1.02 +1.020.7270.4930.7781257012287128034.2858f
194470___________ +1.17 +1.130.0050.0090.0211222414247138696.335__
191330___________ +1.48 +1.270.0020.0030.0091493222057190106.959__hypotheticalprotein
195065___________ +1.37 +1.260.0040.0060.0221346218503169366.1522_requiredforretentionofluminalERproteins
*19367____________ +1.43 +1.280.0160.0190.0563810954496488876.2061_
*193370___________ +1.83 +1.720.0000.0010.0002393543765411396.2580_
*191313___________ +1.93 +1.760.0020.0040.0081497428864263166.3101_opaque-specificmultidrugresistancetransporter
192756___________ +1.22 +1.140.0060.0070.0411333216284151386.3588_HDELreceptorforERproteinretention
*192362___________ +1.53 +1.580.0010.0040.0031576324093248906.4078_involvedinrRNAprocessing
*1955_____________ +1.36 +1.710.0000.0030.0002701836670460806.4551_conservedhypotheticalintegralmembraneprotein
*191967___________ -2.01 -1.890.0010.0020.0025637028053298436.5037_mitochondrialribosomalprotein
*196315___________ +2.06 +1.800.0010.0020.0031523631344274346.5508_hypotheticalprotein
192044___________ +1.07 +1.020.1400.0660.6091408615098144316.5983_hypotheticalprotein
*191623___________ +1.75 +1.610.0000.0010.0005196391133837736.6449_transcriptionalactivatorinvolvedinoxidativestressresponse
*195663___________ -1.46 -1.360.0010.0030.0072988520429219806.6903_conservedhypotheticalprotein
194861___________ +1.06 +1.040.0610.0360.2911305513830135936.7351_
*193052___________ +2.09 +2.230.0000.0000.000708031477031577046.7789_GTP-bindingproteinoftherabfamily
193241___________ +1.17 +1.120.0070.0090.0311951022799218896.8241_hypothticalprotein
*195436___________ +1.42 +1.690.0010.0080.0022128630186360416.8670_
*195917___________ +11.76 +8.480.0000.0000.000214502523461818936.9120_zincfingerproteininvolvedinpre-tRNAsplicing
1942_____________ -1.07 -1.060.0940.1930.0841179010970110896.7____transportprotein
*196242___________ +1.47 +1.310.0080.0160.0221304819193171326.674__hypotheticalprotein
*19246____________ +1.30 +1.250.0010.0030.0071824823748227316.1273_
*192887___________ +2.48 +2.360.0000.0000.000565501403321332296.1818_
193894___________ -1.09 -1.110.0280.2260.0201188410868106946.2345_Myo-inositoloxygenase
191766___________ +1.29 +1.260.0200.0240.0661242316022156836.2871_similartoputativehydrolase
196494___________ -1.06 -1.090.0450.1910.0351177711123108236.3360_
192394___________ +1.20 +1.140.0110.0120.0581222614705139346.3854_
*193405___________ +1.68 +1.610.0000.0000.0002776146618445896.4326_hypotheticalprotein
*19607____________ +2.35 +2.300.0000.0010.0013400279876783236.4823_
*191359___________ +1.30 +1.240.0160.0190.0612388131077296896.5291_hypotheticalprotein
193571___________ +1.13 +1.120.0430.0380.1371293514631144326.5758_hypotheticalprotein
*196608___________ +1.72 +1.650.0010.0030.0023028652065498726.6221_
*194542___________ +1.22 +1.130.0300.0280.1073223039425364116.6688_cyclin|TFIIKsubunit,asubcomplexoftranscriptionfactorTFIIH
*196875___________ +1.17 -1.010.0230.0100.7414805056297475926.7139_retrievalofvacuolarsortingreceptor
196048___________ +1.12 -1.050.0820.0510.2943231836343306536.7592_mannosyltransferase
*197136___________ +1.96 +1.740.0010.0030.0041926937854336126.8033_
*197080___________ -1.67 -2.170.0010.0050.00110128460595465966.8473_isopropylmalatedehydrogenase
197558___________ -1.01 -1.040.3120.7470.1661486014652142336.8908_
43104____________ +1.01 -1.020.6440.7930.4151432314512141054.3104_
*191555___________ +1.71 +1.480.0010.0020.0062572644065379696.355__involvedinprocessesaffectingtheactincytoskeletonandmitosis|leucinepermeasetranscriptionalregulator
191348___________ +1.27 +1.200.0020.0040.0101319816767158236.981__hypotheticalprotein
192869___________ +1.14 +1.060.0240.0160.1821252114260132236.1537_hypotheticalprotein
*191382___________ +1.33 +1.270.0010.0020.0031747323245221916.2082_
193769___________ +1.27 +1.220.0010.0020.0031654121036201356.2598_
*191709___________ -1.60 -1.740.0010.0070.0028735654494501006.3118_sterolcarrierprotein
*192786___________ +1.91 +1.740.0000.0010.0011870535662324936.3603_clathrinassociatedproteincomplexlargesubunit
*191757___________ +1.69 +1.710.0220.0200.0961854231377317526.4092_transcriptionalregulatorcontainingaC2H2zincfinger
195685___________ -1.06 -1.060.2200.1400.4071237801165121166886.4563_threonyl-tRNAsynthetase
195859___________ +1.18 +1.180.0150.0420.0231378016263162766.5051_allantoatepermease
*196329___________ +1.36 +1.340.0000.0010.0012181729729292766.5523_
*196460___________ +1.43 +1.370.0050.0090.0161843126278251756.5999_AAAATPase,peroxisomalbiogenesis
193442___________ +1.08 +1.100.0860.1020.1284343847008477176.6463_NADPHdehydrogenase
*195677___________ +1.72 +1.810.0020.0080.0051536426425278486.6917_ureapermease
*194845___________ +1.84 +2.010.0000.0020.00149740913801000926.7366_conservedhypotheticalprotein
*193064___________ -2.83 -2.890.0000.0000.00012532344323434216.7801_mitochondrialribosomeproteinL27
193254___________ +1.03 +1.020.2630.1280.7191361014058138226.8253_
*195447___________ -15.14 -12.960.0000.0000.00059384239218458066.8683_sugartransporter
*195904___________ +1.23 +1.280.0090.0170.025943051161771211486.9133_ribosomalproteinL19A(L23A)(rpl5L)(YL14)
*192003___________ +2.03 +1.800.0000.0000.0012021140993363476.42___
194863___________ +1.10 +1.080.1180.0540.6172460027009265356.690__
*196225___________ +1.98 +1.910.0000.0000.0003125461896597026.1290_
*193724___________ +1.51 +1.840.0000.0020.0002835742903520546.1835_processingof20Spre-rRNA
*19262____________ +1.39 +1.280.0040.0050.0261379619244177086.2358_
193368___________ +1.19 +1.060.0300.0160.3731242814749132356.2892_hypotheticalprotein
192521___________ +1.51 +1.370.0010.0030.0051488222407203756.3374_
192378___________ -1.04 -1.080.2470.4170.1672944528390271906.3870_
*192201___________ -1.54 -1.400.0020.0050.0053588223367256226.4340_pre-mRNAprocessingprotein|translationalactivator
*191722___________ -1.37 -1.240.0020.0030.0253052422328246196.4838_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*193707___________ -2.93 -2.560.0000.0000.0003048001041521192066.5305_
*196343___________ +1.46 +1.390.0000.0010.0012471536058342386.5772_involvedinsynthesisof1,3-beta-glucan,acomponentofthecellwall,andelongationoffattyacidsupto24carbons|1,3-beta-glucansynthasesubunit|fattyacidelongaserequiredforsphingolipidformation
*196105___________ -1.37 -1.150.0110.0130.0549579070032835236.6236_mevalonatepyrophosphatedecarboxylase
19812____________ +1.13 +1.060.0740.0420.3481247214155131756.6703_hypotheticalprotein
*196891___________ +1.96 +1.700.0010.0030.0061735434043295756.7154_
*196061___________ +1.38 +1.330.0020.0050.0051820825152241336.7605_conservedhypotheticalprotein
*197150___________ +2.12 +3.150.0000.0000.0001137732409243585746.8050_transcriptionalrepressor
197067___________ -1.01 +1.050.9230.8420.7699029289578950146.8487_
*197574___________ +2.42 +2.810.0000.0010.0012101250927589486.8923_
K_actin__________ +1.09 +1.060.1700.1120.351127011381213459Kactin_
19568____________ +1.12 +1.140.1920.2910.1551677018861190396.371__
*192549___________ +1.58 +1.570.0010.0040.0031511623829238026.1004_
193960___________ +1.00 +1.070.5100.6950.3171991819956212526.1553_DNA-directedDNApolymerasedelta
193409___________ +1.31 +1.230.0170.0250.0451229916146150796.2097_
194155___________ +1.03 -1.000.2480.1140.8261200412389119646.2619_hypotheticalprotein
191159___________ +1.25 +1.180.0120.0210.0301472318381173666.3134_homoserineO-acetyltransferase
*192439___________ -1.51 -1.350.0040.0050.0343320022026245266.3617_mitochondrialacylcarrierprotein
*192590___________ +1.92 +1.620.0010.0020.0101302224973211536.4109_
*192814___________ +1.57 +1.840.0000.0010.0001939530545355966.4579_hypotheticalprotein
195608___________ +1.18 +1.210.0030.0100.0081542418217186496.5064_DNA-directedRNApolymeraseIII
192310___________ +1.03 +1.020.3930.2390.5751221012607125016.5540_conservedhypotheticalprotein
19732____________ +1.00 -1.020.7580.6190.6431337513423131266.6011_carbonylreductasesimilartoSOU1andSOU2
*193665___________ +1.11 +1.190.0050.0810.0043126334648371906.6476_putativeHLHtranscriptionfactor
193116___________ +1.19 +1.200.0030.0120.0051741720710209126.6929_yeastU1snRNPproteinwitharolein5'splicesiterecognition
*194830___________ +1.29 +1.310.0000.0010.0012301529754302516.7381_hypotheticalprotein
*196440___________ +1.22 +1.340.0040.0130.0092215426966297816.7815_
193267___________ -1.02 -1.030.6980.8220.4601219111981118326.8267_DHHCzincfingerprotein
*195462___________ -1.60 -1.260.0090.0090.0728443052832672346.8698_hypotheticalprotein
195892___________ +1.05 +1.020.6460.4470.6701228212928125416.9148_
191745___________ +1.07 +1.020.1540.0780.5321327314241135136.70___
194866___________ +1.24 +1.170.0070.0090.0351264915625147636.707__probableprotein-tyrosinephosphatase
*195758___________ +3.39 +3.220.0010.0030.0041847462717594726.1305_
*193143___________ +1.45 +1.350.0020.0030.0122536436769341166.1854_transposase
192024___________ +1.20 +1.110.0100.0090.0891290915521143186.2375_hypotheticalprotein
19169____________ +1.09 +1.090.2080.1110.5371481716086161896.2905_phosphatidyl-ethanolamineN-methyltransferase
195049___________ +1.20 +1.150.0050.0060.0441277815310147116.3388_
*191332___________ +1.58 +1.400.0000.0010.0042586040763361356.3885_drugtransporter
*195505___________ +1.33 +1.170.0010.0030.0072696635764314986.4353_imidazoleglycerolphosphatesynthase|histidinebiosynthesis
195779___________ -1.12 -1.140.0100.0320.0161167410420102736.4850_
196156___________ -1.14 -1.140.0100.0330.0151172510327102686.5317_conservedhypotheticalprotein
196358___________ -1.28 -1.170.0050.0110.01311628908899446.5787_ubiquitinconjugatingenzyme
196090___________ -1.14 -1.160.0260.0510.0431228410791106226.6253_
19828____________ -1.16 -1.140.0070.0170.016115469961101236.6719_mitochondrialribosomalprotein
196904___________ -1.16 -1.110.0070.0160.0181167410059105206.7168_translationinitiationfactoreIF2Bsubunit
196074___________ -1.13 -1.140.0130.0510.0171176410394103116.7618_nuclearproteininvolvedinoxidativestressresponse
197163___________ -1.11 -1.150.0070.0480.0091169410498101686.8063_hypotheticalprotein
197054___________ -1.19 -1.130.0070.0150.017116969806103736.8499_hypotheticalprotein
197590___________ -1.22 -1.170.0020.0060.00711674958099956.8938_
19620____________ +1.26 +1.170.0080.0090.0451303716382152566.387__hypotheticalprotein
195177___________ +1.20 +1.140.0150.0190.0511251214968143266.1026_
*196252___________ +1.23 +1.090.0300.0200.2052467430328269406.1568_conservedhypotheticalprotein
*195741___________ +2.42 +2.010.0000.0010.0011560137771313956.2112_agglutininlikeprotein1
19712____________ +1.29 +1.190.0040.0070.0171242815997147896.2633_kinesin-relatedproteininvolvedinmitoticspindleassembly
194979___________ +1.34 +1.150.0230.0240.0811215816344140416.3148_
*19754____________ -1.59 -1.490.0000.0000.0006075138271406996.3633_conservedhypotheticalprotein
195553___________ +1.31 +1.190.0020.0030.0091750622911209136.4123_conservedhypotheticalprotein
*194759___________ -4.45 -3.800.0000.0000.0005654141270291488826.4596_cytochrome-coxidasesubunitVa
*191237___________ +1.95 +2.080.0010.0050.0021622531631336776.5080_
*192678___________ +1.55 +1.500.0000.0020.0012613840394392356.5556_ser/thrproteinkinaseinmitosischeckpoint
*196265___________ -1.32 -1.490.0020.0120.0033632827510244606.6024_ribosomalprotein
193678___________ -1.15 -1.210.1390.2090.1311260451098621044536.6489_hypotheticalprotein
193102___________ +1.10 +1.030.3140.1560.7482624528878270826.6943_hypotheticalprotein
*196965___________ -2.58 -2.630.0000.0000.0003185961232821209466.7393_
*196424___________ +1.17 +1.200.0170.0280.0413732643834448606.7830_E2ubiquitin-conjugatingenzyme
*193281___________ +1.54 +1.370.0040.0090.0151450922410199356.8281_conservedhypotheticalprotein
197463___________ +1.05 +1.060.0830.0600.2291458215302155176.8714_
195874___________ +1.01 -1.010.8400.7840.6521210012162119526.9163_similartoopaquephaseproteinOP4
*191149___________ -1.30 -1.390.0060.0150.0153740328708268616.100__
*195614___________ -1.06 -1.200.0230.1960.0172651824966220486.727__
192227___________ +1.41 +1.310.0030.0050.0141400919751182896.1320_putativesulfatetransporter
193804___________ +1.19 +1.170.0060.0090.0301631119354191246.1867_
192530___________ +1.27 +1.120.0050.0050.0431240015719139446.2389_hypotheticalprotein
*195742___________ +1.49 +1.480.0020.0070.0051478822103218646.2923_orf6.2923
195125___________ +1.09 -1.120.3680.6390.2154518249022401956.3406_conservedhypotheticalprotein
19416____________ +1.21 +1.120.0100.0100.0661445017453161366.3899_hypotheticalprotein
*193506___________ +1.52 +1.570.0010.0040.0041789727163280616.4366_RNAlariatdebranchingenzyme
*192996___________ +1.25 +1.210.0030.0070.0082220827732268146.4869_involvedincellwallbiogenesisandarchitecture
196169___________ +1.05 +1.090.0150.0180.0581242713010135976.5330_conservedhypotheticalgene
19996____________ +1.19 +1.070.0290.0280.1031520718125162326.5802_hypotheticalprotein
*19397____________ -2.12 -2.340.0000.0010.0014185119754178886.6267_mitochondrialribosomalproteinofthelargesubunit
*19519____________ +1.51 +1.360.0010.0020.0041828027560249016.6731_weaklysimilartorDNAtranscriptionalactivatorUAF
196917___________ +1.27 +1.260.0010.0020.0021607920362202586.7181_conservedhypotheticalprotein
*196529___________ +2.15 +1.980.0000.0000.0003026864952599666.7631_ubiquitin-conjugatingenzyme
*197178___________ +1.57 +1.550.0000.0000.0004013463043621536.8078_20Sproteasomealpha-typesubunit
*197350___________ -2.91 -3.210.0000.0000.0003221531105981002376.8511_
*197602___________ -1.15 +1.010.0420.0180.6614806641680487356.8950_conservedhypotheticalprotein
19713____________ +1.17 +1.120.0230.0230.0901222314349136916.407__conservedhypotheticalprotein
19849____________ +1.16 +1.110.0260.0200.1481203013986133526.1043_
196234___________ +1.12 +1.110.0490.0400.1561429015948158546.1584_conservedhypotheticalprotein
191049___________ +1.20 +1.070.0430.0350.1491242814862133326.2131_8-oxo-dGTPase
192625___________ +1.10 +1.010.1960.1340.3511180113039118636.2649_hypotheticalprotein
*194317___________ -1.25 -1.020.0490.0260.3702434319547239686.3169_aldosereductase
194188___________ +1.09 +1.030.0850.0640.2191285214014132696.3645_nuclearimport|importinbetafamily
19748____________ +1.18 +1.110.0190.0160.1021370616186152826.4137_nuclearporeprotein
*194307___________ +1.21 +1.160.0170.0330.0341895122988220476.4612_Rad52inhibitor
196016___________ -1.04 +1.000.8860.7100.8081245411945124896.5095_
*192337___________ -1.32 -1.090.0040.0020.5503820628904349156.5571_high-affinitypermeaseforbasicaminoacids
196277___________ -1.05 -1.040.2750.4140.1911171011151112076.6036_conservedhypotheticalprotein
19433____________ -1.06 -1.010.6140.3690.8111484814055147126.6502_weakhomologytoKRE11,involvedinbiosyntheticpathwayforcellwallbeta-glucans
195177___________ +1.40 +1.320.0010.0030.0061621622700213606.6959_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*193997___________ -2.00 -1.500.0000.0000.001170165885042011362366.7410_alcoholdehydrogenase1
196407___________ +1.08 +1.010.3650.1820.8291504116291151556.7847_zincfingerprotein
195306___________ -1.06 -1.070.1620.3800.1061455213675136156.8295_
*197479___________ +1.53 +1.630.0000.0010.0002561839132417626.8731_neutraltrehalase(alpha,alpha-trehalase)
193787___________ -1.06 -1.070.0600.2680.0421174911066109746.153__
195518___________ +1.29 +1.200.0060.0100.0281337417280160536.745__
191609___________ +1.59 +1.400.0030.0060.0141371421840192436.1340_
193201___________ +1.21 +1.160.0050.0060.0311263215245146786.1884_amatinglocusregulatoryprotein
194574___________ +1.25 +1.210.0080.0100.0381290416117155716.2402_
62938____________ +1.19 +1.110.0100.0100.0591250714844138346.2938_
192185___________ +1.27 +1.160.0060.0060.0601290216381149676.3421_Nopsevenassociated|ribosomebiogenesis
*192507___________ +1.43 +1.250.0010.0010.0042162030979270186.3912_actin-relatedprotein
*191799___________ -1.51 -1.580.0030.0080.0095333435283337616.4378_
191321___________ +1.09 +1.190.0130.0780.0141376915063164076.4884_
191578___________ -1.14 -1.100.0150.0350.0271161410194105916.5342_processingofpre-rRNAto18Sand5.8SrRNA
196366___________ -1.24 -1.170.0010.0030.005117409455100596.5818_hypotheticalprotein
195094___________ -1.19 -1.120.0090.0210.020116749831104696.6282_ubiquitin-mediatedproteindegradation
19535____________ -1.14 -1.200.0630.3880.038119461045099396.6747_hypotheticalserine-richprotein
193298___________ -1.23 -1.140.0100.0290.019117509522103026.7194_
196515___________ -1.15 -1.150.0060.0230.0101174610188102346.7645_heatshockprotein90
197190___________ -1.19 -1.110.0080.0290.0141283610821115956.8091_
197364___________ -1.19 -1.140.0070.0190.016118309954103346.8524_flavin-containingmonooxygenase
197615___________ -1.19 -1.160.0060.0170.011116569754100606.8963_targetingcomplex(TRAPP)componentinvolvedinERtoGolgimembranetraffic
6424_____________ +1.36 +1.190.0040.0050.0231288017557153316.424__
191442___________ +1.32 +1.230.0040.0060.0271276016820157466.1059_
195063___________ +1.46 +1.340.0020.0050.0081514622048202986.1609_
191077___________ +1.31 +1.100.0060.0060.0751300017009142946.2146_
191774___________ +1.09 +1.050.0610.0380.2721345314704140716.2663_
1972_____________ +1.03 -1.020.4300.9270.2302508825949246956.3182_copperuptaketransporter
19762____________ +1.12 +1.090.0250.0210.1161255614113136916.3662_sphingomyelinphosphodiesterase
*191687___________ +1.64 +1.770.0010.0050.0032018233080357796.4152_RNAhelicaseinvolvedinspliceosomedisassembly
*195702___________ +1.33 +1.180.0110.0170.0332214929399261206.4633_
196132___________ -1.04 -1.110.0650.2750.0452358822735212006.5113_hypotheticalprotein
1923223__________ -1.02 -1.120.0330.1120.0342441623902218366.5585_NA
*194941___________ +1.57 +1.360.0040.0070.0222204634587300096.6049_basichelix-loop-helixtranscriptionfactor
*196621___________ +1.67 +1.540.0010.0030.0042032633874313886.6519_
195164___________ -1.05 +1.060.8190.6230.7632761226321291596.6972_alpha-1,6-mannosyltransferase
*194010___________ +1.34 +1.330.0010.0030.0021965026379261666.7423_componentofPab1p-stimulatedpoly(A)ribonuclease
196390___________ +1.09 +1.040.1120.0510.6131185912883123646.7864_hypotheticalprotein
195320___________ +1.31 +1.210.0070.0110.0231579920682190696.8309_negativeregulatorofcts1expression
197491___________ -1.02 -1.070.4360.7920.2431478214426138796.8743_regulationofmitochondrialnetwork
192430___________ +1.40 +1.200.0020.0030.0151450120352174406.169__
191996___________ +1.30 +1.250.0030.0060.0131277416558159366.766__
61356____________ +1.33 +1.230.0030.0050.0171353517956166066.1356_
19853____________ +1.22 +1.160.0400.1160.0411826922328211146.1902_Gpi-anchoredasparticprotease
*194368___________ +2.03 +2.020.0000.0010.0021477129986298756.2421_
*194490___________ +1.34 +1.400.0080.0260.0143796350834530146.2951_ribosomalproteinL17B
191829___________ +1.28 +1.160.0040.0050.0451383417703160596.3436_
196020___________ +1.35 +1.200.0020.0030.0231321917877158286.3924_involvedinautophagocytosisduringstarvation
*193203___________ +1.33 +1.230.0030.0050.0161868024800228936.4396_F-boxprotein:endocyticmembranetraffic,recycling
194788___________ +1.09 +1.210.2310.5040.1384920253672594616.4898_N-acetyl-gamma-glutamyl-phosphatereductaseandacetylglutamatekinase|N-acetyl-gamma-glutamyl-phosphatereductaseandacetylglutamatekinase|acetylglutamatekinaseandacetylglutamyl-phosphatereductase
*191404___________ +1.20 +1.180.0050.0200.0092045224447242186.5357_tRNAdihydrouridinesynthase
196382___________ +1.24 +1.120.0230.0200.1131299916065145186.5832_
*195077___________ -1.95 -1.960.0000.0010.00112718465366649896.6299_hypotheticalprotein
*19548____________ +2.88 +2.300.0000.0000.0002528972913580486.6760_septininvolvedincytokinesis,cellwallorganization,conjugation,andcelldivision
*193311___________ +1.22 +1.090.0200.0110.3442193826704239406.7206_oxidoreductase
196501___________ +1.09 +1.100.0350.0290.1361281113936140746.7659_
197203___________ -1.07 -1.090.0650.0740.1172151520047196696.8103_mitochondriallargeribosomalsubunit
197376___________ +1.06 +1.070.1190.0980.2221230813005131746.8536_hypotheticalprotein
197629___________ +1.08 +1.050.1090.0600.4041280213787135006.8976_
19632____________ -1.00 -1.000.5070.4900.3961360813583135646.443__hypotheticalprotein
191593___________ +1.38 +1.210.0020.0030.0171520320928184506.1071_ser/thrproteinkinase|glycogensynthasekinase3
194880___________ +1.11 +1.020.3840.2050.7171206213365122616.1625_hypotheticalprotein
191273___________ -1.01 -1.020.1230.0990.2311505614834147806.2165_prefoldinsubunit4
191240___________ +1.12 +1.060.0560.0340.2801257514127132686.2679_
193213___________ +1.05 +1.040.2790.1390.7061264213263131246.3195_
195220___________ +1.05 +1.040.2130.1550.3331243613078129226.3681_RNAEXonuclease;memberof3'->5'exonucleasefamily
*191378___________ +1.46 +1.570.0010.0030.0031551122647243516.4165_
193548___________ +1.07 +1.060.0960.0760.2151492215928157986.4653_conservedhypotheticalmembraneprotein
196227___________ +1.05 +1.000.2640.1220.8571195912554119946.5129_potentialC2H2Zincfingerdomain
191939___________ +1.08 +1.070.0500.0600.0961429215380152916.5600_conservedhypotheticalprotien
194168___________ -1.01 -1.030.2360.1270.5521200511930116566.6062_
196636___________ +1.04 +1.000.3240.1530.9381194912463119856.6533_conservedhypotheticalprotein
1968332__________ -1.02 -1.040.0850.3660.0521511414774144956.6985_NA
194023___________ +1.03 +1.150.4950.6630.3125925060952679266.7436_mitochondrialribosomalsmallsubunitprotein
194582___________ +1.09 +1.020.1060.0450.7981291314118131746.7881_3'->5'exoribonucleaseinvolvedinrRNAprocessing|superkiller
*195334___________ -1.42 -1.430.0040.0100.0104325830457301656.8323_Zincfingercontainingprotein
*197504___________ +1.92 +2.550.0000.0000.0002781853458710726.8756_conservedhypotheticalprotein
19508____________ -1.08 -1.100.0350.1170.0351221611279110686.183__
191624___________ +1.21 +1.130.0090.0090.0681261915239142026.786__
1973_____________ +1.39 +1.200.0020.0030.0391393419392167216.1372_
*193930___________ +1.36 +1.140.0040.0040.0722374732216271686.1916_putativeubiquitincarboxyl-terminalhydrolase-likeprotein
195230___________ -1.16 -1.330.0130.0460.0182489321493187616.2438_40SribosomalproteinS9,mitochondrialPRECURSOR
194415___________ +1.24 +1.120.0080.0070.0841476818314166066.2967_hypotheticalprotein
195207___________ +1.31 +1.200.0030.0050.0141364517882163296.3450_diphthaminesynthasesubunit
195295___________ +1.09 +1.040.0580.0250.7321684818282175506.3939_conservedhypotheticalprotein
*194046___________ +1.23 +1.180.0080.0130.0273060137769361226.4412_conservedhypotheticalprotein
195731___________ -1.14 -1.100.0150.0240.0401154610120104626.4910_phenylacrylicaciddecarboxylase
192137___________ -1.11 -1.110.0200.0600.0261159410481104196.5371_conservedhypotheticalprotein
193881___________ -1.20 -1.150.0510.0320.2661283210689111816.5851_
194391___________ -1.17 -1.140.0070.0190.016116949987102986.6316_hypotheticalprotein
196665___________ -1.18 -1.120.0370.0690.055115469802103386.6775_
19336____________ -1.16 -1.150.0040.0160.0081225610563106556.7220_mitochondrialmatrixiron-sulfurprotein
195270___________ -1.18 -1.110.0110.0230.025115549810103996.7672_conservedhypotheticalprotein
197215___________ -1.13 -1.120.0080.0310.0131167410333104666.8115_conservedhypotheticalprotein,possiblyU3snoRNPprotein
197388___________ -1.15 -1.090.0230.0320.0581225710678112806.8548_memberoftheHOG1MAPkinasecascade|tyrosineproteinkinaseoftheMAPkinasekinasefamily
197644___________ -1.17 -1.120.0150.0380.0271200410293107286.8992_ubiquitin-proteinligase;AnaphasePromotingComplex
*194689___________ +1.67 +1.430.0010.0020.0041499624971213866.461__hypotheticalprotein
191606___________ +1.39 +1.330.0060.0120.0161274617732170056.1087_hypotheticalprotein
*191671___________ +1.56 +1.500.0000.0010.0012407037602360206.1639_cellwallprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194731___________ +1.24 +1.090.0160.0120.1341242515379135076.2184_
193154___________ +1.02 -1.020.5210.5750.3661868719049182916.2694_
19470____________ +1.13 +1.070.0170.0150.0931406615831151016.3210_
*19683____________ -2.76 -3.020.0000.0000.00011501841692380936.3696_adenylatekinase
195486___________ +1.31 +1.400.0090.0240.0191277116667179306.4180_subunitofpolyadenylationfactorI
195491___________ +1.07 +1.060.0990.0940.1751243313274131526.4666_hypotheticalprotein
193904___________ +1.05 +1.060.2730.2030.3621209212680127586.5144_hypotheticalprotein
191852___________ -1.03 -1.070.1930.1080.4812294322282214816.5618_
194182___________ +1.03 -1.010.4830.2550.9181374814182135846.6076_weaksimilarityto3-oxoacyl-[acyl-carrier-protein]reductase
*196649___________ +1.51 +1.490.0000.0010.0012509337792373166.6546_transcriptionfactorIIIB|RNApolymeraseIIItranscriptionfactor
196849___________ +1.34 +1.290.0010.0030.0051533020589198526.6998_transcriptionelongationfactor
194036___________ +1.02 +1.010.7010.4290.9832233522808225076.7450_
*194596___________ +1.69 +1.700.0010.0030.0021553226187264126.7895_hypotheticalprotein
*195350___________ +1.23 +1.200.0290.0390.0685121662866614786.8339_CTDkinase-Igammasubunit
*197518___________ +1.26 +1.300.0100.0270.0183358042144437506.8770_transcriptionalregulatorofnitrateassimilation
*1948_____________ +1.55 +1.370.0010.0020.0091564224275215056.202__RNasePsubunit
1988_____________ +1.06 +1.040.6360.9680.3872364625033245976.810__
191298___________ +1.33 +1.170.0040.0040.0321279216988149796.1389_
19553____________ +1.25 +1.170.0020.0040.0131255915720146716.1930_dityrosinetransporter
*191604___________ +1.50 +1.360.0040.0070.0191355020391184316.2452_
191109___________ -1.03 -1.060.2640.2180.3142330522536220426.2985_hypotheticalprotein
191112___________ +1.35 +1.160.0070.0060.0781204816312139486.3464_involvedinbud-siteselection
193764___________ +1.40 +1.280.0010.0040.0061503221105192656.3955_ERtoGolgitransportprotein(TRAPP)
195588___________ +1.05 +1.080.1270.0990.2421263013262136056.4430_conservedhypotheticalprotein
*191065___________ -2.51 -2.450.0000.0000.0006238602488912541876.4924_chaperoninoftheHSP70family
192154___________ -1.09 +1.010.8050.7270.6326498659392656136.5389_
*193130___________ +1.57 +1.640.0000.0010.0003334252452548056.5867_highlyconservedhypotheticalprotein
195122___________ +1.13 +1.080.0180.0150.1141305814818140976.6328_hypotheticalprotein
196681___________ +1.10 +1.080.0840.0690.1932315925559250696.6790_hypotheticalprotein
*19349____________ +1.44 +1.600.0000.0010.0002173631202348266.7233_regulatorofmitochondrialsynthesisofAtp6pandAtp8p
*195258___________ +1.59 +1.420.0010.0020.0021583925187224966.7684_conservedhypotheticalprotein
*197229___________ +1.70 +1.560.0040.0070.0191671828455260456.8130_
*197401___________ +1.58 +1.380.0010.0030.0071901730097261666.8561_chromatinremodelingcomplex
197661___________ +1.05 -1.000.2170.0960.9441234612951122866.9009_mitochondrialDNAhelicase
194225___________ +1.39 +1.230.0080.0110.0301462020360180006.484__
*194777___________ -1.11 -1.170.0440.0660.0733191728880273426.1104_
193146___________ +1.06 -1.020.2120.0940.9801223612945119996.1656_hypotheticalprotein
196246___________ -1.02 +1.030.6660.3970.9771790217555184216.2198_N-terminalacetyltransferase
193627___________ +1.18 +1.130.0420.0380.1251348115840152376.2712_conservedhypotheticalprotein
193937___________ +1.11 +1.030.1660.0890.4871312614591134746.3224_SporulationDeFiciency
196480___________ +1.05 +1.050.3760.2830.4201194612518125626.3714_vanadateresistanceproteinGog5
194503___________ +1.01 +1.010.9490.7900.9091678316892169666.4195_conservedhypotheticalprotein
192582___________ +1.37 +1.430.0020.0050.0051466020114209846.4683_highlyconservedhypotheticalprotein
19215____________ +1.10 +1.040.1390.0740.4531180212963122736.5159_
19325____________ +1.03 +1.100.1480.6350.0762392524708262066.5633_pre-mRNAcleavageandpolyadenylationspecificityfactor
192174___________ -1.03 -1.060.3750.6750.2151175811368110446.6089_DNA-repair|RecAhomolog
19669____________ +1.09 +1.020.1260.0590.5971196213000121816.6562_pheromone-regulatedmembraneprotein
*196861___________ +1.36 +1.360.0000.0020.0012060527944279886.7010_anaphase-promotingcomplex
*192092___________ -1.02 +1.290.0120.5450.0073838237635493226.7463_cystathioninebeta-lyase
*194610___________ +1.71 +1.440.0040.0060.0241276921772184336.7909_carboxypeptidaseyscS
195365___________ +1.01 +1.040.2820.1920.4121267112760131976.8355_conservedhypotheticalprotein
*197537___________ +1.75 +1.690.0010.0030.0051574227570266676.8787_
*196382___________ +1.67 +1.650.0010.0030.0051562526159257556.12___
198______________ +1.25 +1.190.0470.0250.3601266715887151186.506__hypotheticalprotein
19230____________ +1.10 +1.090.0300.0290.1031244113653135356.1121_
*191771___________ +1.64 +1.750.0010.0030.0031664427296290996.1677_cellcyclecontrolprotein
*196464___________ +2.27 +1.970.0000.0010.0021644337391324366.2213_
192713___________ +1.23 +1.110.0160.0170.0701738021313193276.2729_meiosis-specificmutShomolog
191727___________ +1.24 +1.210.0120.0140.0551284815884155696.3238_Ca2+-transportingP-typeATPase
*193089___________ -3.02 -3.070.0000.0000.00011913939406387926.3732_possiblyinvolvedinintramitochondrialsorting
*192341___________ -3.91 -5.900.0000.0000.00023379759777396496.4211_similaritytoproteinkinaseCinhibitor-I,histidinetriadnucleotide-bindingproteins
*192740___________ +1.74 +1.570.0020.0040.0061517226327237696.4696_
192418___________ -1.10 -1.180.0110.0710.0132786425388235266.5175_conservedhypotheticalprotein
*193972___________ +1.52 +1.490.0000.0010.0012041730977303936.5648_GolgiTransport
193417___________ +1.03 +1.020.4390.3420.4422673427570271706.6108_
*192772___________ +1.28 +1.100.0180.0170.0932757835361303356.6580_histonedeacetylase
191897___________ +1.16 +1.140.0170.0180.0691627818851185836.7023_conservedhypotheticalprotein
*192077___________ +1.75 +1.420.0010.0020.0062804249111398776.7478_hypotheticalzincfingerprotein
*194624___________ +1.35 +1.460.0030.0090.0091474019968215786.7923_Ty3transpositioneffector
*197286___________ +1.72 +2.120.0010.0040.0021583027176335996.8368_
196829___________ +1.06 -1.000.1390.0660.6071350214264134786.8802_proteinrequiredfortheexpressionofsubunit-9ofatpsynthase
Cacda2___________ -1.02 -1.040.7750.8530.537121961192711684Cacda2_
19230____________ +1.37 +1.200.0020.0030.0221249217055149756.218__
*191933___________ +1.71 +1.880.0010.0050.0031637927991308116.829__
*191977___________ -2.25 -2.510.0000.0000.00011469150902456716.1407_dihydrooratase
193516___________ -1.11 -1.010.1670.0960.4272368521355233496.1949_conservedhypotheticalprotein
*192156___________ -1.47 -1.590.0010.0050.0035530137610347756.2470_glucosamine-6-phosphatedeaminase
*191097___________ +12.68 +14.360.0000.0000.000535706792537694206.3000_agglutininlikeprotein4
*19133____________ -1.96 -1.670.0000.0010.0012306581177231383806.3481_hypotheticalprotein
*194251___________ +1.83 +1.700.0010.0020.0031482827206251636.3973_
*19308____________ -1.16 -1.190.0020.0090.0043641531445306976.4446_nitroguanidineresistance
*192846___________ -1.37 -1.150.0010.0010.0282974021763259416.4940_hypotheticalprotein
*196183___________ -1.98 -1.960.0000.0000.0007646438669390866.5404_mitochondrialproteinimportmachinerysubunit
*192263___________ -1.32 -1.490.0020.0070.0064577134780306766.5883_hypotheticalprotein
*195104___________ +1.43 +1.490.0010.0030.0025052072107751966.6346_protein-tyrosine-phosphatase
*196698___________ -1.62 -1.620.0000.0000.0003881423898239936.6807_asn-tRNAsynthetase
*194437___________ +1.30 +1.160.0070.0100.0322421831376281006.7249_ATPasecomponentofafoursubunitchromatinremodelingcomplex
195245___________ -1.10 -1.060.0860.0570.2643030727671286366.7697_ubiquitinligasebindingprotein
*197244___________ -4.38 -4.750.0000.0000.00013374230559281756.8144_conservedhypotheticalprotein
*197414___________ +1.41 +1.380.0010.0040.0032162230384297546.8576_
*197675___________ -5.88 -8.060.0000.0000.000775932131851962646.9022_
*192455___________ +1.15 +1.290.0220.0710.0273139636077406346.33___
*192848___________ +2.57 +2.570.0010.0030.0051380935545355536.525__
*19195____________ +1.33 +1.240.0010.0020.0042320330764288856.1144_hypotheticalprotein
194330___________ +1.13 +1.110.0160.0140.0961342215117148746.1693_
*193599___________ +2.50 +2.730.0000.0000.0002563564094699466.2229_
*193635___________ +2.28 +2.340.0000.0010.0002373654213556096.2749_
194330___________ +1.29 +1.180.0060.0080.0271482419121174266.3257_
*19847____________ +3.90 +4.240.0000.0000.0002158784238914736.3747_mitochondrialinnermembraneprotease
*194893___________ +1.77 +1.840.0000.0000.000576561019431060916.4229_conservedhypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*194658___________ +1.56 +1.790.0010.0030.0012763743097493506.4709_zinc-fingerproteinwithcoiledcoildomain
*194297___________ +1.97 +2.300.0000.0020.0011984439113456556.5189_
*192626___________ +1.40 +1.480.0080.0160.0205143372160762576.5661_
*192901___________ +1.31 +1.730.0020.0150.0041534520041265316.6122_
192760___________ +1.10 +1.070.0400.0330.1431292614176137866.6592_
*191883___________ +1.41 +1.430.0020.0040.0071789425143255136.7038_
*192065___________ +1.54 +1.350.0010.0020.0031702226299229656.7490_allantoinase|nitrogenandsulfurmetabolism
197011___________ +1.05 +1.030.3110.1470.8811297913689133526.7937_pre-rRNAprocessing
197301___________ +1.08 +1.060.0960.0500.4361357114683143706.8382_
196813___________ +1.08 +1.080.0570.0680.1061338314446144626.8818_hypotheticalprotein
Cafks1___________ -1.01 +1.020.8900.8660.694119321181712127Cafks1_
*195061___________ +1.59 +1.740.0000.0000.0003007447721524416.238__
191209___________ +1.18 +1.160.0070.0120.0261256814850145196.842__hypotheticalprotein
*194779___________ +1.81 +2.230.0000.0010.0011628329449362896.1423_
*191913___________ +1.08 +1.120.0360.1920.0282661728647298556.1966_hypotheticalprotein
194067___________ +1.18 +1.090.0180.0150.1071274515006138376.2485_hypotheticalprotein
*191246___________ +2.10 +2.420.0010.0030.0021905439953460296.3013_
*195182___________ +1.71 +1.850.0000.0010.0002691745990497426.3494_
*194349___________ +1.66 +2.110.0000.0020.0011680227916355166.3993_conservedhypotheticalprotein
195519___________ -1.03 -1.040.6870.6480.5143072629841294266.4461_glycinecleavageTprotein
*1924781__________ -2.21 -1.960.0000.0000.0004573302069482337076.4956_NA
*196203___________ +1.46 +1.370.0010.0020.0041816826506248386.5420_
192248___________ -1.20 -1.010.2210.0980.9184417436768438606.5898_acyl-CoAsterolacyltransferase
*192000___________ +1.31 +1.320.0020.0050.0051830423991240906.6360_requiredformitoticchromosomesegregationandmeioticrecombination
194116___________ +1.01 +1.020.9900.9260.9302171921961221626.6820_conservedhypotheticalprotein
*194449___________ -1.80 -1.750.0000.0000.00011873465802679316.7262_copperchaperoneinvolvedinlysinebiosynthesisandoxidativestressprotection
195231___________ -1.11 -1.110.0400.0720.0601971517833177516.7711_
*197258___________ -1.55 -1.300.0020.0020.0275888837894452956.8159_
*197433___________ +1.88 +2.090.0020.0080.0061516128526317386.8590_
*196000___________ +4.46 +5.760.0000.0000.000505862255972916146.9037_multidrugresistanceprotein|ABCtransporter
*194347___________ +2.93 +2.540.0000.0000.000475701393341205916.50___
*195181___________ +1.93 +1.910.0020.0050.0081576230397300596.547__histidinekinaseosmosensor
191803___________ +1.31 +1.180.0080.0100.0381272816614150736.1162_geranylgeranyltransferasebetasubunit
194697___________ +1.22 +1.120.0150.0120.1251424617364159356.1711_
*191392___________ -1.18 -1.320.0120.1330.0115143743693389026.2244_proteindisulfideisomerase
194220___________ -1.15 -1.280.0020.0260.0032416020958188966.2765_conservedhypotheticalprotein
*192857___________ +2.12 +2.280.0010.0030.0031534432568349766.3274_
193459___________ +1.38 +1.250.0040.0060.0221588021989198596.3762_serine/threonine/tyrosineproteinkinaseinvolvedinchromosomesegregation
191282___________ -1.01 -1.030.6710.9660.4181888018642182636.4243_cyclin-dependentkinasesregulatorysubunit
19576____________ +1.19 +1.170.0220.0650.0291548218449181566.4726_kinetochorecomponent
194283___________ +1.16 +1.090.0330.0370.0871597218448174126.5203_relatedtotranslationinitiationfactorandCOP9/signalosomesubunit
196138___________ -1.01 +1.040.5950.9200.3551293412838134276.5676_ferricreductasetransmembranecomponent
192889___________ +1.09 +1.080.0270.0310.0781282013984138426.6133_conservedhypotheticalprotein
*194240___________ -1.54 -1.840.0000.0000.0005593036332304046.6605_involvedinmanganesehomeostasis
*67051____________ +3.13 +2.580.0000.0000.0002915491167752926.7051_
*193810___________ +1.27 +1.200.0060.0060.0544358755177523896.7505_methylenetetrahydrofolatedehydrogenase|NAD-dependent5,10-methylenetetrahydrafolatedehydrogenase|NAD-dependent5,10-methylenetetrahydrafolatedehydrogenase|methylenetetrahydrofolatedehydrogenase(NAD+)
197024___________ +1.05 +1.080.0450.0670.0741487415544161076.7950_hypotheticalprotein
*197314___________ +1.32 +1.520.0000.0020.0011974725992299916.8395_cysteinedioxygenase
*196801___________ +2.06 +2.110.0150.0460.0221686034693355916.8830_histonedeacetylase;transcriptionmodifier
Caskn1___________ -1.04 +1.040.6170.3770.789122311175912681Caskn1_
194357___________ +1.28 +1.240.0020.0040.0081710921975212006.252__
*191189___________ +3.84 +3.320.0000.0000.000440231691381461286.861__
*19119____________ +1.24 +1.100.0260.0470.0461404017404155046.1442_
*192990___________ +4.27 +3.590.0000.0010.0011830978199657326.1982_glucan1,3-beta-glucosidase
*1996_____________ +1.82 +2.260.0000.0030.0013546864702801996.2499_
193648___________ -1.05 -1.000.6660.4170.8152470023588246376.3029_putativetranscriptionalco-activator
193964___________ +1.20 +1.130.0100.0120.0411955423527221106.3507_transcriptionfactor,containsaPHDfingermotif
*192942___________ +2.66 +2.500.0000.0000.0003067781558768266.4006_dicarboxylicaminoacidpermease
*193178___________ +1.80 +1.820.0000.0020.0012206939787401816.4476_
*192465___________ +1.34 +1.300.0060.0120.0172725036558353456.4971_
196283___________ +1.14 +1.100.0330.0330.1011399815902153616.5433_mitochondrialmatrixprotein
*194931___________ +1.78 +1.810.0000.0010.0013161256332573346.5911_cysteinyl-tRNAsynthetase
*191412___________ -1.22 -1.220.0030.0060.0086856156345560706.6381_hypotheticalprotein
194099___________ -1.05 +1.170.6140.9390.3693592353433164213456.6837_extracellularsulfitereductase
*19900____________ +5.00 +6.470.0000.0000.000229581147661484666.7275_
196978___________ +1.08 +1.110.0180.0280.0431303314141144656.7724_hypotheticalprotein
*197274___________ +1.49 +1.430.0010.0030.0061621124125232046.8173_
197444___________ +1.23 +1.210.0020.0090.0041917023537232676.8604_conservedhypotheticalprotein
*195985___________ -1.16 -1.140.0060.0110.0193329328722292626.9052_polypeptideofanon-nativeactinbindingcomplex
*1958_____________ +1.50 +1.400.0030.0080.0081265019013177736.74___
19915____________ +1.36 +1.190.0030.0040.0241280917469151966.568__leucinerichrepeatprotein
19114____________ +1.24 +1.200.0080.0130.0261277215861153116.1182_hypotheticalprotein
19707____________ +1.11 +1.040.0830.0480.3452010622243209816.1727_componentoftheautophagicsystem
*193756___________ +1.46 +1.440.0040.0100.0101340919611193666.2262_DEADboxRNAhelicase
191148___________ +1.20 +1.130.0060.0090.0231227614675138996.2785_
193617___________ +1.27 +1.150.0020.0030.0191430018184164386.3287_smallGTPasethatmaybeinvolvedinthefunctionofthePho84phosphatetransporter
194361___________ +1.26 +1.160.0080.0090.0411267715978147186.3779_
192210___________ +1.32 +1.290.0010.0030.0071692822315219216.4255_
192119___________ +1.10 +1.100.0250.0330.0641845620310202616.4743_
194812___________ +1.02 +1.010.7570.5000.8691424214493143356.5218_holo-(acyl-carrierprotein)synthase|holo-ACPsynthase|4'-phosphopantetheinyltransferaseacpS
19590____________ +1.08 +1.010.1070.0520.5071535016647154666.5690_ABC-typenitrate/sulfonate/bicarbonatetransport
195832___________ +1.11 +1.130.0160.0270.0361538717139173756.6146_hypoxanthineguaninephosphoribosyltransferase
194223___________ +1.19 +1.080.0220.0230.0831283115285138466.6621_
*19501____________ +1.15 +1.190.0080.0310.0122806232333335276.7068_
193825___________ +1.00 -1.050.1790.6240.0942131621322202726.7520_proteaseinvolvedinrasanda-factorterminalproteolysis
197037___________ -1.06 -1.100.0260.1140.0251952218362177876.7963_essentialprotein,unknownfunction
197326___________ +1.12 +1.120.0140.0310.0261341714992150696.8407_conservedhypotheticalprotein
196788___________ +1.06 +1.150.0270.0290.0811252613324143816.8843_hypotheticalprotein
41894____________ +1.09 +1.070.0580.0560.1351347514623144554.1894_
19718____________ +1.23 +1.250.0030.0060.0091367016852170916.273__
196349___________ +1.31 +1.170.0050.0050.0451378118060161036.878__
192637___________ +1.11 +1.100.0230.0310.0581902021018208696.1458_involvedinmanganesehomeostasisandproteinprocessing
19247____________ +1.26 +1.200.0030.0040.0191471818511175946.1995_
194127___________ +1.37 +1.210.0010.0010.0051564821475188576.2515_
194525___________ +1.12 +1.080.0220.0210.0901362615214147716.3046_membraneproteinwithweakhomologytoNADH-ubiquinoneoxidoreductase
19636____________ +1.24 +1.150.0110.0110.0661272615778146046.3523_hypotheticalprotein
*194749___________ +1.31 +1.190.0090.0120.0361378817998164016.4019_hypotheticalmembraneprotein
*192830___________ -1.51 -1.400.0010.0010.0043400522547242736.4491_U3snoRNPprotein
*193476___________ +1.78 +1.610.0000.0000.0023452661318554766.4983_caseinkinaseI
196299___________ +1.11 +1.150.0070.0100.0281486416503170516.5449_ubiquitinactivatingenzyme

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
1931_____________ +1.04 +1.030.6870.4200.9141528515933157726.5926_
191426___________ +1.24 +1.110.0100.0090.0851543719105171706.6394_
*194088___________ -1.49 -1.340.0010.0010.0046161241226458306.6849_
19886____________ +1.08 +1.000.1580.0710.7352101122641210456.7290_
196990___________ -1.14 -1.160.0070.0180.0142198019346189246.7736_peptidyl-prolylcis-transisomeraseD|cyclophilinD
19938____________ -1.01 -1.020.2350.8650.1161679116573164536.8187_hypotheticalprotein
197456___________ +1.29 +1.180.0040.0050.0301374217781162566.8616_hypotheticalprotein
195971___________ +1.06 +1.040.1170.0520.6691380714627143546.9066_conservedhypotheticalprotein
*194546___________ +1.50 +1.520.0020.0040.0091609924206244886.97___
194395___________ +1.24 +1.190.0030.0070.0101533819096183106.590__
*191435___________ -1.68 -2.080.0000.0040.0013497302083511682646.1201_
191178___________ +1.04 +1.070.1190.1140.1871242812970133496.1743_
193954___________ +1.30 +1.200.0030.0060.0131301816973155956.2277_phosphatidylserinedecarboxylase
194346___________ +1.08 +1.060.0570.0400.2121227413206130166.2801_
193660___________ +1.29 +1.240.0030.0070.0091502719341186376.3301_hypotheticalprotein
195722___________ +1.10 +1.060.0550.0410.1871369815074145896.3797_DNA-bindingprotein
*192615___________ +1.27 +1.120.0020.0030.0132723434609304626.4270_ATP-bindingcassettetransporterfamilymember
*192103___________ +1.48 +1.380.0040.0080.0121907028249263306.4758_
194144___________ +1.02 -1.010.5900.3460.8291675417134165786.5235_
192983___________ -1.03 -1.030.5310.5400.3931657116101160456.5706_accessoryfactorassociatedwithRNApolymeraseII
192476___________ -1.02 +1.010.9200.8180.7781347313262136506.6159_
195802___________ +1.07 +1.060.1980.1630.2771579216934167156.6637_
19488____________ +1.11 +1.040.1500.0840.4312127423619220846.7083_nuclearmRNAexport,poly(A)+RNAbindingprotein
*193840___________ +1.47 +1.330.0020.0050.0102198332387292466.7535_DNApolymerasealphasuppressingproteinkinase
*195032___________ +1.23 +1.210.0160.0400.0272693373319293272216.7977_proteininvovledincontrolofDNAreplication
197340___________ +1.10 +1.040.0250.0120.4831333814691139016.8421_hypotheticalprotein
*196776___________ +1.47 +1.630.0030.0080.0081540922608251266.8856_
43011____________ +1.06 +1.070.6940.4640.7531220412900130404.3011_
*192135___________ +1.40 +1.210.0110.0090.1102372633124287976.287__
*193193___________ +1.66 +1.600.0010.0030.0031475024543235866.907__
192778___________ +1.34 +1.190.0050.0070.0311292817314154416.1475_conservedhypotheticalprotein
*191052___________ +6.11 +4.560.0000.0000.000253761551471157106.2008_histone2B
192749___________ +1.29 +1.170.0050.0070.0271305216887153276.2534_
*194799___________ +1.44 +1.420.0030.0060.0121423120544202336.3058_myb-relatedDNA-bindingproteinrequiredduringG2/Mtransition
*191500___________ +1.35 +1.290.0020.0050.0101594121451204926.3541_
*195101___________ +1.13 +1.060.0140.0110.1122809031744296946.4036_glucose-repressibleADHtranscriptionaleffector
*195636___________ -6.29 -5.340.0000.0000.00027736564406835192646.4505_repressedbyTUP1protein5
*194513___________ +1.49 +1.390.0040.0060.0181455421727201966.4997_
*193733___________ -5.20 -8.700.0000.0000.00029895357511343556.5462_
*19207____________ +1.36 +1.400.0030.0080.0091436419521200936.5942_
*191549___________ -1.31 -1.330.0040.0140.0093847629334289836.6407_hypotheticaltransmembraneprotein
*196713___________ +1.73 +1.800.0000.0010.0014696381170847286.6863_
19873____________ -1.13 -1.160.0110.0500.0142517322234216456.7304_hypotheticalprotein
*193012___________ -1.19 -1.180.0040.0120.0093127826312264816.7749_conservedhypotheticalprotein
*19951____________ +1.69 +1.370.0010.0010.0243485058821476326.8200_hypotheticalprotein
195393___________ -1.02 -1.060.3130.7210.1682373423187224836.8629_glutamatedecarboxylase
*195960___________ -1.54 -1.740.0010.0040.0013125342027161800036.9077_non-classicalproteinexportpathway
192116___________ +1.23 +1.220.0030.0070.0101616819889196856.118__N-acetyltransferaseforN-terminalmethionine
192360___________ +1.27 +1.200.0020.0030.0081484518866177576.610__
191830___________ +1.23 +1.180.0070.0100.0291268815598149926.1220_hypotheticalprotein
*194686___________ +1.29 +1.160.0140.0100.1531447618721168576.1766_
*193354___________ -2.54 -2.620.0000.0000.00011223444161428656.2294_40Sribosomalprotein
194405___________ +1.27 +1.120.0070.0070.0531260316066141716.2823_tyrosinephosphatase
195038___________ +1.39 +1.200.0020.0030.0111525521158183726.3315_tRNA(guanosine-2'-O-)-methyltransferase
192560___________ +1.24 +1.150.0070.0090.0391323316438152526.3810_
*193538___________ +1.42 +1.510.0030.0080.0101242117632187326.4284_ferricreductase
195616___________ +1.18 +1.110.0080.0090.0481236014646136826.4775_
193863___________ +1.08 +1.060.0650.0490.2031314814253139836.5253_hypotheticalprotein
*191253___________ +1.34 +1.300.0010.0030.0032219129676288706.5720_myc-familytranscriptionfactor
192494___________ +1.05 +1.010.3640.1760.9461395614665140636.6174_
192964___________ +1.22 +1.140.0040.0060.0251607919658182646.6652_MemberofRSCcomplex,whichremodelsthestructureofchromatin
191474___________ +1.19 +1.130.0140.0120.0921431017094161416.7098_
*196565___________ -1.90 -1.870.0010.0020.0023574918858190816.7552_
*195019___________ +1.35 +1.330.0080.0100.0321758023705232986.7991_
197119___________ +1.02 -1.010.8940.8170.7251859819052184506.8433_
*196763___________ +2.45 +2.610.0000.0010.000522031281131364916.8868_
43032____________ +1.07 +1.060.0660.0710.1261177312595125004.3032_
*191277___________ +1.72 +1.590.0020.0040.0101411824251224426.303__
193952___________ +1.32 +1.220.0040.0060.0271267016680154486.928__
192805___________ +1.27 +1.170.0030.0050.0251306816635153086.1492_
194464___________ +1.16 +1.130.0150.0180.0571292414986146286.2031_lowhomologytotRNAsplicingendonuclease
*19802____________ +1.50 +1.340.0020.0030.0151426321463191396.2549_
194553___________ +1.19 +1.110.0070.0070.0571653619717183676.3073_
192458___________ +1.16 +1.160.0040.0120.0101634218941188826.3559_
193925___________ +1.19 +1.110.0140.0110.1341271415081140536.4051_hypotheticalprotein
195651___________ +1.36 +1.240.0010.0030.0101554421123192876.4520_
194209___________ +1.13 +1.120.0100.0190.0271568817721175436.5012_ubiquitin-activatingenzyme
193748___________ +1.14 +1.080.0220.0260.0681213513784130556.5477_
195140___________ +1.06 +1.030.1570.1260.2581339014245137276.5958_hypotheticalgenefamily
*191564___________ -2.33 -1.950.0000.0000.0027324331409375486.6421_conservedhypotheticalmembraneprotein
196727___________ -1.08 -1.050.0470.0950.0592268621081215986.6876_ribosyltransferaseofinitiatortRNAmethionine
196931___________ +1.02 -1.030.5640.6880.3671764018007170816.7318_
193026___________ -1.29 -1.220.0030.0060.0142229417320183406.7763_mitochondrialprocessingprotease
19966____________ +1.09 +1.010.2780.1310.8151523416610153556.8215_dihydrouridinesynthase
*195409___________ +1.46 +1.440.0010.0020.0022035829676293256.8645_putativetranslationinitiationfactor
195947___________ +1.11 +1.090.0550.0490.1461442715963156606.9093_
*195065___________ +1.35 +1.240.0030.0060.0141937426128240946.133__
*193158___________ +1.49 +1.330.0010.0030.0071653524598219966.641__
193172___________ +1.24 +1.150.0050.0070.0271344416697155046.1239_hypotheticalprotein
193289___________ +1.01 -1.100.2460.5340.1443546835881323906.1779_hypotheticalprotein
193852___________ +1.10 +1.210.0050.0170.0081300814284157666.2314_
194965___________ +1.05 +1.080.0680.0890.1041208812703130226.2840_hypotheticalprotein
*19704____________ -1.66 -1.900.0000.0010.00012698476597668106.3328_conservedhypotheticalprotein
195287___________ +1.07 +1.030.0990.0620.3041563816711160436.3826_SET-domainprotein
*19295____________ +1.30 +1.180.0040.0060.0202473532032292706.4299_
*195631___________ +1.11 +1.130.0310.0440.0661587017626178836.4790_hypotheticalprotein
*196548___________ -1.23 -1.420.0010.0130.0013637429525256926.5266_iron-sulfurclusternifU-like
191266___________ +1.03 +1.030.2010.1130.4781232212660127276.5733_hypotheticalprotein
*195767___________ +1.45 +1.530.0010.0030.0031761025567268606.6192_
192952___________ +1.05 +1.040.3050.2330.3681625717095169326.6664_exo-1,3-beta-glucanase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*191460___________ +2.24 +2.280.0000.0000.0003801285074865796.7113_glutamine-dependentNAD(+)synthetase
196580___________ +1.20 +1.090.0100.0100.0651585619048173246.7568_hypotheticalprotein
*195005___________ -1.34 -2.110.0000.0250.0003540332639781677276.8004_osmoticgrowthprotein
*197106___________ +3.37 +4.920.0000.0020.0011452048949714316.8447_membraneproteininvolvedinvacuolarproteinsorting
*196748___________ +1.58 +1.490.0010.0030.0033408553781507856.8883_translationinitiationfactor
42795f--1________ +1.08 +1.090.0320.0310.1031231413262134274.2795f
*19362____________ -1.09 -1.290.0100.2860.0072443542239271896046.322__transcriptionalactivation
19182____________ +1.34 +1.230.0030.0070.0121341617997164516.944__
*192655___________ +1.57 +1.410.0000.0000.0014936277626694446.1509_cellcyclearrestprotein
*193586___________ +2.32 +2.270.0000.0000.0002362054913535416.2045_
*19111____________ +3.06 +2.570.0000.0010.0011421943576365646.2564_
63087____________ +1.10 +1.110.0200.0270.0581288914124142596.3087_
*192210___________ +1.79 +1.560.0010.0030.0061514827049235556.3574_hypotheticalprotein
194672___________ +1.16 +1.130.0130.0100.1341270614790143536.4064_hypotheticalprotein
*194372___________ +3.60 +3.220.0000.0000.00030444109725980696.4537_probablemembranetransportprotein
193329___________ +1.01 +1.010.8030.6490.6934897249490495806.5025_sphingosine-1-phosphatephosphatase
192704___________ +1.17 +1.090.0200.0150.1271252414691136686.5492_hypotheticalprotein
192033___________ +1.14 +1.060.0230.0260.0721514217332161176.5972_hypotheticalprotein
*191637___________ +1.24 +1.210.0050.0160.0095337766172646306.6435_conservedhypotheticalprotein
*195651___________ +2.25 +2.450.0000.0000.0002578457984631136.6892_
*196947___________ -1.68 -1.730.0000.0030.00116227996362940556.7333_glutathioneS-transferase
193041___________ +1.30 +1.360.0010.0050.0031637521266223186.7778_conservedhypotheticalproteinwithsimilaritytoROD1
19980____________ -1.09 -1.090.0530.0520.1273861335409354336.8229_methionineN(alpha)-acetyltransferase
*195423___________ +1.52 +1.460.0000.0010.0021938029433283736.8659_hypotheticalprotein
195930___________ +1.01 +1.020.4340.2740.5731235212531125806.9107_nuclearporeprotein
19162____________ +1.30 +1.190.0030.0050.0181384618009164446.147__hypotheticalprotein
*196257___________ +1.80 +1.310.0020.0030.0191389225052181916.655__
192647___________ +1.37 +1.220.0030.0040.0161465820138178536.1256_
*193388___________ +1.23 +1.140.0120.0090.1521417417494161436.1802_
*191650___________ -2.20 -2.010.0000.0000.0005958227064296006.2330_
*19457____________ +1.30 +1.620.0040.0150.0091472819216238876.2858_
*194645___________ +2.18 +2.070.0000.0010.0011794939173371846.3343_
194882___________ +1.11 +1.020.3780.1990.7374523650085463326.3841_RNApolymeraseIITFIIEsmallunit
*194475___________ +1.39 +1.440.0000.0030.0012501934749361116.4312_putativemannosyltransferase
19280____________ +1.16 +1.100.0090.0110.0441320015335145246.4809_hypotheticalprotein
193010___________ +1.11 +1.160.0410.0550.0801906821135220936.5279_lipoatebiosynthesisprotein
*191670___________ +1.30 +1.300.0010.0030.0026935890281903976.5745_involvedinintegralmembraneproteintrafficking
*196596___________ -1.75 -1.260.0030.0030.0599316853252740386.6208_esterase
*194531___________ +3.55 +4.070.0000.0000.00026482940121078066.6677_ATP-dependentABCtransporter
*191446___________ +2.01 +1.860.0000.0010.0014315886927802006.7127_G2/mitotic-specificcyclin|B-typecyclin
*196036___________ +1.25 +1.420.0020.0100.0032024025270287736.7580_partofcomplexthatcatalysesguanylnucleotideexchangeonYpt6p
194991___________ +1.27 +1.250.0050.0100.0171566019944196296.8019_
197093___________ +1.07 +1.060.1670.0850.5471696918237179576.8460_sugartransporter-likeprotein
197548___________ +1.14 +1.260.0050.0240.0071736019756218696.8896_DNA-directedRNApolymeraseIIholoenzymeandkornbergsmediator
42858f___________ +1.02 +1.050.2140.2760.1861188312135124894.2858f
194468___________ -1.13 -1.180.1630.1370.2473865934177327656.336__succinatedehydrogenasemembraneanchorsubunit
191329___________ +1.40 +1.240.0030.0050.0121390819436173006.960__hypotheticalprotein
*192815___________ +1.24 +1.280.0010.0040.0022068325552264116.1523_pantothenatesynthase
19374____________ +1.18 +1.110.0080.0090.0421261514892139586.2064_
*193370___________ +1.65 +1.740.0010.0040.0031512824952263696.2581_
*191311___________ +1.29 +1.290.0010.0030.0022004425778258726.3102_relatedtoyeastsporulationprotein
192757___________ +1.30 +1.290.0020.0050.0091520319816196496.3589_conservedhypotheticalprotein
*192361___________ +1.23 +1.190.0170.0170.0761474118125175086.4079_
*1954_____________ +4.21 +5.590.0000.0000.00022506947401258346.4552_RepressedinHyphalDevelopment|familyofconservedproteinofunknownfunction
*191966___________ +1.28 +1.370.0000.0030.0012081826646284266.5038_budsiteselectionprotein
*196316___________ +1.22 +1.390.0010.0090.0014673957137647426.5509_integralmembraneprotein
*192045___________ +1.51 +1.570.0000.0000.0002191633183343926.5984_ERmembraneprotein
*191621___________ +1.18 +1.280.0020.0140.0033526741571450736.6451_guaninenucleotide-bindingregulatoryprotein
*195664___________ +1.12 +1.120.0140.0310.0272279525421256416.6904_conservedhypotheticalprotein
194858___________ +1.04 +1.070.0940.0740.2121240612882132816.7352_vacuolarproteinsorting
*193053___________ -5.40 -4.470.0000.0000.000509882943681139686.7790_hypotheticalprotein
193242___________ +1.05 +1.040.1140.1710.1191335413957138886.8242_transcriptioninitiationfactorTFIIDsubunit
*195436___________ +1.29 +1.400.0060.0090.0221441118625201046.8671_
195915___________ +1.03 +1.070.1810.2740.1511296013333138676.9121_
1944_____________ +1.21 +1.130.0090.0100.0461272115348143886.9____ReCYcling
192720___________ +1.13 +1.100.0160.0180.0631255814249138206.675__
*192850___________ +2.46 +3.170.0000.0020.0011809444424573426.1274_
*192886___________ +1.88 +1.790.0000.0010.0012359544297421616.1819_MAPkinaseinvolvedinpheromonesignaltransduction
*193893___________ +1.84 +1.840.0000.0000.0005002691980918106.2346_SolubleCellWallprotein
193703___________ +1.38 +1.320.0040.0070.0141420619544187296.2874_
196496___________ +1.34 +1.340.0020.0050.0081448019343193956.3361_TRAPPsubunit;Golgitrafficking
*192393___________ +1.26 +1.220.0040.0110.0122833035731345176.3855_polyadenylationfactorsubunit
193404___________ -1.00 -1.050.3440.7320.1871563615611149226.4328_
*19606____________ +1.22 +1.070.0210.0140.1983659744766389936.4825_conservedhypotheticalprotein
191360___________ +1.11 +1.120.0260.0350.0641925621303216496.5292_conservedhypotheticalprotein
*193569___________ +1.30 +1.170.0150.0140.0821433818632167896.5759_
*196610___________ +1.42 +1.380.0030.0050.0121484121063204556.6223_
*194543___________ -2.28 -3.060.0000.0000.00012405854405405626.6689_succinate-semialdehydedehydrogenase|involvedinutilizationofGABAasanitrogensource
196877___________ +1.01 +1.050.3190.4080.2351204212190126816.7142_
*196049___________ +1.50 +1.650.0010.0040.0021414021240233236.7594_
*197136___________ +1.64 +1.720.0010.0040.0041946431878334146.8037_
*197079___________ +1.32 +1.130.0040.0040.0472708935637306986.8474_cellcycleregulatedproteinrequiredforaxialbudformation|3-isopropylmalatedehydrogenase
*197561___________ +3.18 +3.310.0000.0000.000329111046821089996.8910_
43070____________ +1.04 +1.050.1770.1170.3521235412810130294.3070_
194258___________ +1.40 +1.240.0020.0030.0081472620627183086.357__componentofapre-mRNApolyadenylationfactor
*195121___________ +1.93 +1.600.0010.0020.0041581130489253746.982__
192455___________ +1.11 +1.080.0340.0330.1041217213567131916.1539_highlyconservedhypotheticalprotein
*194732___________ +1.90 +1.660.0000.0010.0022108439998350996.2083_
19135____________ +1.27 +1.180.0040.0090.0161301416577153286.2599_
191708___________ +1.18 +1.110.0160.0160.0731229714522135936.3119_hypotheticalproteinofconservedsyntenywithrelatedS.cerevisiaeprotein
192787___________ +1.23 +1.190.0020.0040.0101275615685151566.3604_
*191756___________ +1.74 +1.680.0010.0020.0035354393085902006.4093_glycerol-3-phosphatedehydrogenase
*195686___________ -3.01 -3.300.0000.0000.0006467621490196036.4565_
65052____________ +1.41 +1.420.0020.0040.0091528221500217726.5052_
*196336___________ +1.17 +1.160.0110.0220.0262467028797285596.5525_
196459___________ +1.27 +1.270.0020.0040.0071819723123231056.6000_diacylglycerolpyrophosphatephosphatase
*193441___________ +1.53 +1.270.0130.0150.0531106991698441411106.6464_putativetransporter
*195678___________ +1.71 +1.840.0010.0030.0012307839471424346.6918_conservedhypotheticalprotein|similartodiphteriatoxinresistanceprotein
*194844___________ +1.65 +1.600.0000.0010.0012364438981377676.7367_argininemethyltransferase-interactingRINGfingerprotein
*193065___________ -1.16 -1.310.0030.0250.0033397429163259336.7802_D-aminoacidoxidase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*193255___________ +1.46 +1.620.0020.0050.0041430520940231976.8255_hypotheticalprotein
*195449___________ +1.24 +1.270.0020.0040.0104175851605529166.8684_
195903___________ +1.08 +1.030.2340.1440.4391219213135125886.9134_similartoB-chainsoftheinsulin-relatedsuperfamily|maybeinvolvedinbudsiteselection
19815____________ +1.25 +1.180.0060.0080.0251297616177153436.45___
*19254____________ +2.23 +2.030.0000.0000.0002679059764543986.691__hypotheticalprotein
*191991___________ +1.37 +1.300.0000.0010.0022695636800350596.1291_memberofthemajorfacilitatorsuperfamily
193722___________ +1.55 +1.380.0020.0040.0111352520955186206.1836_
*19265____________ +1.86 +1.880.0010.0030.0051536428513288256.2360_hypotheticalprotein
193367___________ +1.11 +1.030.1020.0570.3821903121054196326.2893_
192520___________ +1.05 -1.070.3200.7160.1731935320351181626.3376_
193694___________ +1.28 +1.220.0030.0050.0141388617708169416.3872_hypotheticalprotein
*192200___________ +1.63 +1.610.0010.0030.0031665027158268596.4341_vesicularintegral-membraneproteinVIP36-like
*191721___________ -1.77 -1.540.0000.0010.0025341030108347136.4839_conservedhypotheticalprotein
193708___________ +1.16 +1.160.0100.0150.0331269814740147086.5306_secretedasparticproteinase
196344___________ -1.14 -1.090.0510.0790.0773569431380327136.5773_ribokinase
*196102___________ -1.25 -1.290.0210.0270.05710719585414828326.6239_ATF/CREBactivator
*19813____________ +1.82 +2.220.0000.0020.0004054373943900026.6704_hypotheticalprotein
196893___________ +1.26 +1.210.0040.0100.0101994125157241256.7157_
*196062___________ -2.38 -2.780.0000.0010.00111093846581398856.7606_conservedhypotheticalprotein
197151___________ +1.14 +1.120.0120.0200.0351341015297150476.8051_hypotheticalprotein
*197065___________ +1.36 +1.340.0010.0030.0022317431457310996.8488_conservedhypotheticalprotein
197576___________ +1.02 +1.050.4750.3680.4641457014815153096.8924_probablemethyltransferase
p18a=p19_________ +1.14 +1.100.0100.0090.074143331633815795p18a=p1
192455___________ +1.36 +1.230.0080.0080.0501274817348157376.373__
192549___________ +1.19 +1.180.0050.0080.0181297415463153526.1006_
193959___________ +1.35 +1.420.0540.0880.0763952853317562846.1554_
193411___________ +1.19 +1.120.0120.0110.0791254814943140296.2100_involvedinbudsiteselection
*194156___________ +1.53 +1.470.0020.0050.0081287219726188936.2620_hypotheticalprotein
*191160___________ -1.26 -1.390.0020.0080.0042920623250210236.3135_conservedhypotheticalprotein
192440___________ +1.28 +1.140.0110.0090.0941365017523155146.3618_
192587___________ +1.24 +1.260.0050.0090.0171329716509168016.4110_
*1970_____________ +1.66 +1.570.0010.0030.0081506925045236836.4580_hypotheticalprotein
195606___________ +1.13 +1.050.0670.0610.1521261814206133096.5066_hypotheticalprotein
*192308___________ +5.06 +4.770.0000.0000.000236631198281127786.5542_6-phosphofructose-2-kinase
19731____________ -1.02 -1.020.8040.9800.5531523814877149756.6012_involvedinglycoproteinexportfromtheendoplasmicreticulum
193666___________ +1.18 +1.130.0110.0100.0781317115581148266.6477_conservedhypotheticalprotein
*193115___________ +1.15 +1.190.0400.2100.0302417227900287056.6930_hypotheticalprotein
*194829___________ +1.23 +1.320.0020.0120.0023604844218476786.7382_requiredfornormalintracellularubiquitinmetabolismandfornormalratesofproteolysisofubiquitin-dependentproteolyticsubstratesinvivo
*196438___________ +1.30 +1.300.0020.0080.0052259629377294416.7816_serinepalmitoyltransferasecomponentthatcatalysesthecommittedstepinsphingolipidsynthesis,thecondensationofserinewithpalmitoyl-CoAtoform3-ketosphinganine
*193268___________ -2.31 -2.030.0000.0000.0004510881952652226036.8268_translationallycontrolledtumorprotein
195464___________ -1.07 +1.160.4520.8490.2506800563816789786.8700_hypotheticalprotein
*195890___________ +1.29 +1.220.0160.0160.0711270916389154596.9149_
19868____________ -1.19 -1.180.0270.1140.0261202610077101686.72___
191072___________ +1.10 +1.080.0350.0300.1291267713974136736.709__hypotheticalprotein
*191508___________ +1.42 +1.310.0040.0060.0151562422166205286.1306_hypotheticalprotein
*191531___________ +1.31 +1.250.0060.0110.0231897724886236986.1855_
*192021___________ +3.13 +2.690.0000.0010.0012395675065644446.2377_
*19171____________ +1.60 +1.400.0010.0020.0033726759620520936.2906_
195047___________ +1.17 +1.130.0070.0120.0271523917899172406.3389_hypotheticalprotein
*191333___________ +1.52 +1.280.0020.0030.0143540353748453836.3886_drugtransporter
*195506___________ +2.19 +2.500.0010.0020.0021660636355414916.4354_phospholipaseC
*195780___________ +1.31 +1.340.0010.0040.0052565033556343386.4853_
*196160___________ +1.39 +1.270.0040.0040.0541185031647771505266.5318_
196359___________ +1.00 +1.030.4040.2600.5381326013310137206.5788_peptidaseoftheproteinsortingmachinery
*196090___________ +1.95 +2.420.0010.0030.0012261344094547876.6254_
*19829____________ +1.61 +1.780.0030.0080.0101584325461282096.6721_
*196905___________ +1.27 +1.140.0030.0030.0452387830411272376.7169_conservedhypotheticalprotein
*196075___________ -1.32 -1.640.0000.0020.0007734358404472596.7619_transcriptionalregulatorinvolvedincellcycleregulation
*197164___________ -1.22 -1.490.0000.0030.0003205026366215406.8064_serine/threonineproteinkinase
*197053___________ +5.36 +4.450.0000.0000.000265481424201181576.8500_regulatorysubunitforphosphoproteinphosphatasetype1(PP-1)
*197590___________ -1.46 -1.690.0040.0200.0068084255422478276.8939_NADHdehydrogenase(ubiquinone)78Kchainprecursor,5-primeend
*1997_____________ +3.53 +4.630.0000.0010.0001494852738692706.388__
191618___________ +1.50 +1.260.0070.0100.0321217018208153146.1027_
*196253___________ -1.28 -1.360.0000.0030.0007420557854544856.1569_
195741___________ +1.25 +1.170.0050.0070.0321282816090150566.2111_
*19713____________ +1.32 +1.260.0020.0040.0082464032607311216.2634_
194715___________ +1.39 +1.140.0070.0060.0761448620120164456.3150_
19755____________ -1.05 -1.100.1520.3230.1081921418248174556.3634_mitochondrialribosomalproteinL37
*195555___________ +2.11 +2.020.0010.0020.0021462830817296166.4124_
*194758___________ -1.76 -2.100.0010.0040.00215234186486726586.4597_mitochondrialcomplexINUIMTYKYsubunit(protontranslocation)|NADH:UbiquinoneOxidoreductase(ComplexI)
*191234___________ +3.60 +3.510.0000.0010.0011828465756641576.5083_hypotheticalprotein
*192677___________ +1.62 +1.510.0000.0000.0012598642189392136.5557_GPItransamidasecomponent
196266___________ +1.17 +1.190.0090.0140.0291627618975193826.6025_hypotheticalprotein
193679___________ -1.14 -1.170.0680.1220.0797054662067605016.6490_conservedhypotheticalprotein
*193100___________ +1.52 +1.620.0040.0080.0111305019856211696.6944_
*193984___________ +1.54 +1.470.0050.0110.01566496102614977146.7397_
*196423___________ +1.11 +1.130.0280.0260.1033211035501363856.7831_fructose-2,6-biphosphatase
*193282___________ +1.73 +2.170.0030.0120.0071245221573270626.8282_hypoheticalprotein
197464___________ +1.31 +1.200.0040.0050.0381386318193166436.8716_conservedhypotheticalprotein
*195873___________ +1.63 +1.420.0020.0040.0151997532487283326.9164_DNA-directedDNApolymerasealpha
193549___________ +1.27 +1.210.0050.0100.0151378817470166316.102__
195612___________ +1.32 +1.190.0040.0060.0161265016739150866.728__
192228___________ +1.27 +1.190.0030.0050.0191490518924176846.1321_twinfilinA|actinmonomersequesteringprotein
*193809___________ +1.23 +1.170.0250.0200.1322141426334251266.1870_
*192242___________ +2.90 +2.690.0000.0000.0003041988171816876.2390_
1945_____________ +1.25 +1.250.0050.0110.0131308816321163496.2924_agglutinin-likeprotein9
*195124___________ +1.28 +1.300.0010.0040.0022188327969285556.3407_hyphallyregulatedprotein
*19415____________ -1.51 -1.480.0010.0040.0033632223976244806.3900_homologofS.cerevisiaeYGR235C
*193507___________ -3.52 -3.600.0000.0000.00023655467267657986.4367_cytochromeb5reductase
192995___________ +1.21 +1.080.0200.0160.1201409017080152286.4870_lowtemperatureresponsiveprotein
*191589___________ +1.39 +1.310.0040.0060.0151688623400220546.5331_componentofRNApolymeraseIcoretranscriptionfactor
19994____________ +1.03 +1.010.6960.4560.7831500415398151046.5803_
*19396____________ +1.23 +1.220.0100.0110.0571527618769186546.6268_hypotheticalprotein
19520____________ +1.25 +1.290.0050.0120.0141484118486191326.6733_
*196918___________ +1.20 +1.340.0040.0180.0071868422379249896.7182_hypotheticalprotein
196528___________ +1.06 +1.020.3680.2300.5311977521025201686.7632_hypotheticalprotein
*197179___________ -1.23 -1.260.0080.0190.0192946124036234486.8079_heatshockprotein
197353___________ +1.07 +1.040.0760.0500.2531241113339129156.8512_
*197603___________ -1.41 -1.450.0010.0020.0014151029411286006.8951_conservedhypotheticalprotein
19714____________ -1.08 -1.070.1180.1610.1301161710795108206.408__GTPbindingproteininvolvedinvesiclefusioninthesecretorypathway

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
19850____________ +1.44 +1.260.0030.0050.0161226217689154786.1044_amidasespecificforN-terminalasparagineandglutamine
193067___________ +1.12 +1.130.1730.3750.1161416615859160506.1588_partofhistonedeacetylasecomplex
191050___________ +1.28 +1.180.0060.0070.0391249615974147976.2132_
192624___________ +1.26 +1.190.0050.0060.0301256815823149446.2650_hypotheticalprotein
*194318___________ +2.25 +2.110.0010.0020.0051484433387313106.3171_
194189___________ +1.27 +1.130.0060.0060.0491257015962141606.3646_weaksimilaritytoacidphosphatase
*195376___________ +1.19 +1.210.0100.0210.0241649819679199146.4138_proteinkinase
*194308___________ +2.12 +2.170.0010.0040.0051652235050359016.4613_negativeregulatorofswe1kinase
196116___________ -1.08 -1.100.8060.7930.5978538379354777546.5097_aldohexosespecificglucokinase
192336___________ +1.20 +1.140.0040.0090.0151396516766158556.5572_similartotheplantPR-1classofpathogenrelatedproteins
196277___________ +1.02 +1.040.3890.3500.3561247412690129576.6038_
19434____________ +1.08 +1.050.0930.0570.3111289613873135376.6504_
195175___________ +1.23 +1.180.0700.0680.1441342916463158416.6960_
193998___________ +1.22 +1.160.0060.0060.0601381216840160756.7411_hypotheticalprotein
*196406___________ -2.06 -2.380.0000.0010.0015691027586239476.7848_putativemitochondrialribosomalprotein
*195307___________ -32.72 -34.770.0000.0000.00046382114177133386.8296_
197480___________ +1.08 +1.040.1070.0550.4481543916694161196.8732_hypotheticalprotein
19163____________ +1.26 +1.260.0040.0080.0161437218085181246.156__pantoate-beta-alanineligase,pantothenicacidbiosynthesis
6748_____________ +1.07 +1.120.0280.0440.0571264213588141276.748__
191340___________ +1.22 +1.170.0060.0070.0311322416082154916.1342_aldosereductase
*191574___________ +1.36 +1.340.0040.0080.0112181229651292736.1886_TFIIDsubunit|componentoftheTAF(II)complex
194571___________ +1.23 +1.070.0140.0100.1791274815712136016.2404_
*191206___________ +3.35 +3.300.0000.0010.0012277976279751956.2939_irontransportmulticopperoxidase
192186___________ +1.22 +1.130.0120.0120.0651552418982176116.3422_nuclearporeprotein
192508___________ +1.16 +1.080.0200.0150.1481295615023139956.3913_hypotheticalprotein
192870___________ +1.20 +1.060.0760.0320.7521735420830184496.4379_
*191323___________ +1.31 +1.240.0100.0130.0362172828460269356.4885_clathrinassemblycomplexbetaadaptincomponent
191577___________ +1.01 +1.060.1070.1520.1201367613867145316.5343_
*196367___________ -1.64 -1.870.0000.0010.0004999230484267156.5819_heatshockproteinoftheHSP70family
195093___________ +1.03 +1.010.3770.1970.7421974720258199896.6283_chromatinmodeling
*19535____________ -3.13 -2.870.0000.0010.0005453917433190166.6746_
*193300___________ +1.64 +1.510.0010.0040.0052868047030433206.7195_nucleolarzinc-fingerprotein
*196514___________ +2.59 +2.390.0000.0000.0002868074402686246.7646_copperhomeostasis,peptideimportregulation
197192___________ +1.03 +1.050.1100.0840.2391266013094133146.8092_hypotheticalprotein
197365___________ +1.05 +1.050.0830.0800.1561273013356133066.8525_FunctionrequiredforYeastViabilityontoxinexposure
197615___________ +1.01 -1.030.4550.3380.4751625616403157536.8964_
191596___________ +1.33 +1.210.0030.0070.0131299517287157106.426__
*191441___________ +1.35 +1.360.0020.0060.0071990226956271346.1060_hypotheticalprotein
191161___________ +1.31 +1.230.0060.0080.0261322817372162746.1610_phospholipaseD
*191078___________ +1.32 +1.110.0050.0040.1092705535599299826.2148_
191776___________ +1.26 +1.130.0060.0070.0491289216236145676.2664_pantotheine-phosphateadenylyltransferase
194721___________ +1.25 +1.130.0080.0090.0501285016068145736.3183_hypotheticalprotein
19763____________ -1.02 -1.070.3520.9490.1812598725389243746.3663_smallsubunitofthenuclearmRNAcap-bindingproteincomplexCBC
191686___________ +1.27 +1.130.0080.0080.0721572819914178216.4153_conservedhypotheticalprotein
*195710___________ +1.61 +1.560.0020.0040.0091530824704239446.4637_
*196243___________ +1.39 +1.280.0020.0040.0111816525310232936.5115_
192320___________ +1.21 +1.090.0100.0100.0701280215482138996.5586_
194940___________ +1.09 +1.030.0960.0500.4331225213379126746.6050_histidinepermease
196623___________ +1.13 +1.070.0350.0260.1591965822211209896.6520_conservedhypotheticalprotein
*195163___________ +1.24 +1.200.0200.0280.0553883848017464546.6973_mitotictransitionofG2/Mcycle
194011___________ +1.10 +1.100.0190.0200.0711234513615136256.7424_conservedhypotheticalprotein
*196387___________ +1.25 +1.290.0030.0090.0072338629143301666.7866_
195321___________ +1.24 +1.200.0040.0090.0131569619497188726.8310_methylenetetrahydrofolatereductase
*197492___________ +1.18 +1.200.0050.0170.0091698820067203256.8744_conservedhypotheticalprotein
195599___________ +1.17 +1.060.0480.0280.2961237214445131736.170__
191995___________ +1.29 +1.240.0020.0040.0061305216772161486.767__
195568___________ +1.39 +1.260.0010.0030.0081378619132173076.1357_
19854____________ +1.23 +1.080.0060.0070.0392097525801227136.1903_4-aminobutyrateaminotransferase(GABAtransaminase)
194367___________ +1.29 +1.190.3550.9700.1821605820757191476.2422_coiled-coliproteinoftheSMCfamily
194491___________ +1.23 +1.170.0040.0080.0111581219495185236.2952_farnesyldiphosphatesynthetase(FPPsynthetase)|farnesyl-pyrophosphatesynthetase
*191172___________ +2.20 +2.150.0010.0030.0051480832636317666.3437_inorganicphosphatepermease
*196021___________ +1.88 +1.920.0000.0000.0003445164842659766.3925_InducedinHyphalDevelopment
193202___________ +1.33 +1.260.0030.0060.0101712722791216366.4397_membraneproteinsimilartomalarialantigen
194789___________ +1.26 +1.180.0050.0090.0191293716267152356.4899_classIIaldolase
191405___________ +1.21 +1.210.0080.0140.0241309015885157986.5358_p-nitrophenylphosphatase|4-nitrophenylphosphatase
196382___________ +1.07 +1.080.0680.0780.1181251213414135416.5833_
195076___________ -1.33 -1.070.0740.0420.347112326844101052666.6300_profilin
*19549____________ -2.76 -2.990.0000.0000.0007160225987239236.6761_mitochondrialribosomallargesubunitprotein
193312___________ +1.01 -1.020.7240.4760.8201677616977164776.7208_
*195282___________ +2.27 +1.870.0000.0000.0012787263188522586.7660_hypotheticalprotein
197204___________ +1.09 +1.060.0380.0400.0981286814062136446.8104_similarto2-nitropropanedioxygenases
197377___________ +1.08 +1.050.0620.0590.1421225413224128536.8537_anaphasespindleelongationprotein|microtubulebinding
*197629___________ +1.40 +1.630.0030.0090.0061608522588262026.8978_
19633____________ -1.09 -1.070.0520.0960.0671159210652108286.444__putativemethyltransferase
*191594___________ +1.65 +1.490.0020.0030.0191554425622232296.1072_hypotheticalprotein
192670___________ +1.23 +1.180.0040.0060.0181291115869152056.1626_
191274___________ +1.08 +1.070.0840.0620.2241650617867177196.2166_
191244___________ +1.30 +1.190.0120.0150.0481249616195148326.2680_GTPaseactivatingprotein(GAP)forYpt6andMac1interctingprotein
*193214___________ +3.04 +3.360.0000.0010.0011629649484547586.3196_hypotheticalprotein
*195221___________ +1.38 +1.290.0020.0050.0081711823636221626.3682_hypotheticalprotein
*191378___________ +4.96 +5.430.0000.0000.000512762543032786556.4166_
*193547___________ +1.67 +1.760.0010.0040.0022708945347477216.4654_memberofthePUFproteinfamily
196227___________ +1.16 +1.120.0250.0270.0841530017720170826.5130_
191938___________ +1.02 +1.040.4030.3550.3712058720952214476.5601_putativesplicingfactor
194169___________ +1.05 +1.080.1110.1180.1611282713482139096.6063_
*196637___________ +1.18 +1.110.0300.0250.1274405151783488046.6534_predictedglycosilase
*196837___________ -16.65 -16.930.0000.0000.00030556818350180446.6986_benzilreductase
194024___________ -1.00 -1.110.4440.6030.2834774247534431206.7437_riboflavinsynthase
194583___________ -1.11 -1.120.0090.0190.0231847716697164656.7882_mitochondrialcarrierprotein
*195335___________ +1.52 +1.510.0020.0040.0071629424760246306.8325_
68757____________ +1.09 +1.050.0840.0440.4181323714480138926.8757_
192847___________ +1.20 +1.160.0080.0090.0391256815058146396.186__
191622___________ +1.14 +1.090.0420.0370.1341275014530138726.788__
192296___________ +1.22 +1.300.0040.0250.0061506518425196396.1373_hypotheticalprotein
192445___________ +1.25 +1.100.0080.0080.0641291216181142556.1918_
*195229___________ +1.55 +1.480.0050.0110.0171369421275203046.2439_3'-5exoribonucleaserequiredfor3endformationof5.8SrRNA
194411___________ +1.14 +1.130.0320.0320.1041303414854147526.2971_histonedeacetylase
195207___________ +1.10 +1.080.0260.0340.0641327414595143256.3451_
*195294___________ +2.56 +2.470.0000.0000.0003601992192889136.3940_betasubunitofpyruvatedehydrogenase
*194045___________ +1.63 +1.550.0020.0040.0072332037939362186.4413_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*195732___________ +2.31 +2.590.0000.0020.0011913944200494986.4911_nuclear/nucleolarGTP-bindingprotein2
*192138___________ +2.79 +3.210.0000.0010.0012168360483697066.5373_
*193884___________ +1.44 +1.790.0040.0130.0101538222160275286.5853_
194390___________ +1.02 +1.020.8620.6550.8266043061471613436.6317_hypotheticalprotein
*196667___________ +1.43 +1.290.0020.0030.0091983028421255096.6776_subunitofthehistonedeacetylaseBcomplex
19337____________ +1.15 +1.140.0170.0150.0941635718853186736.7221_v-SNAREinvolvedinseveralproteintransportsteps
195269___________ +1.18 +1.160.0040.0060.0151849021851214256.7673_conservedhypotheticalprotein
*197216___________ +1.49 +1.330.0000.0000.0024387165308584046.8116_GTP-bindingproteinoftherab/yptfamily
197389___________ +1.32 +1.280.0020.0060.0061556620579198986.8549_DNApolymerasezeta
*197645___________ +3.47 +3.040.0000.0010.0012257478420685226.8993_biotinholocarboxylasesynthetase
19317____________ +1.12 +1.070.0380.0230.2622053122922219776.462__
*191607___________ +2.81 +2.810.0000.0010.0011904453595535006.1088_
*191672___________ +1.53 +1.360.0010.0020.0051730626462235796.1640_coatomercomplexalphachainofsecretorypathwayvesicles
*194733___________ +1.15 +1.160.0080.0200.0172374227220275296.2186_
*192724___________ +1.72 +1.510.0010.0030.0051547226652233506.2695_hypotheticalprotein
19469____________ +1.24 +1.140.0070.0150.0201814022432206586.3212_MAPkinasekinase(MEK)ofthepheromonepathway
1987_____________ +1.39 +1.300.0010.0040.0041677223302217276.3698_
*195487___________ +1.59 +1.450.0010.0030.0062112133536306016.4181_partofARSreplicationinitiationcomplex
*192568___________ +1.39 +1.350.0010.0030.0031159561606221565666.4670_
193903___________ +1.22 +1.080.0090.0060.1971242815199134156.5145_hypotheticalprotein
*191853___________ +4.70 +3.920.0000.0000.000305161433431196826.5620_histoneH3
194183___________ +1.03 -1.020.5000.2710.8622147422125210076.6077_Pro/Ser-richprotein
196650___________ +1.22 +1.150.0070.0090.0391595219537183276.6547_hypotheticalmembraneprotein
*196850___________ +1.33 +1.250.0010.0020.0044315457486538756.6999_conservedhypotheticalprotein
*194040___________ -1.85 -1.750.0000.0000.00010274255414587406.7451_
*194597___________ +1.27 +1.250.0000.0010.0023969850436495116.7896_F-actincappingproteinbetasubunit
195351___________ -1.04 -1.050.7880.5310.8937490372037715066.8340_translationinitiationfactoreIF1A
*197519___________ +1.33 +1.040.0110.0060.7986706289438694226.8771_hypotheticalprotein
*195623___________ +4.01 +4.080.0000.0000.000268231076111093576.203__
*1990_____________ +1.62 +1.630.0020.0050.0051536024930250856.812__
*192427___________ +1.76 +1.730.0020.0050.0051623328576281006.1391_
19552____________ +1.23 +1.090.0140.0130.0941551719039169156.1931_involvedinbreakdownofautophagicvesiclesinthevacuole
*191605___________ +1.61 +1.630.0000.0010.0011559125084253886.2454_DNAmismatchrepairprotein
*191110___________ +1.40 +1.320.0010.0030.0041718224128226356.2986_thiaminpyrophosphokinase
191113___________ +1.21 +1.180.0070.0140.0201724420912204156.3465_hypotheticalprotein
*193763___________ +1.39 +1.320.0010.0020.0021956627276258836.3956_conservedhypotheticalprotein
*195589___________ +2.46 +2.710.0000.0000.0003612488992979666.4431_hypotheticalprotein
*191064___________ -18.63 -15.730.0000.0000.00082131144090522076.4925_acetyl-coenzymeAsynthetase
*192156___________ -1.93 -2.130.0000.0010.00210127552509476106.5390_
*193131___________ -1.04 +1.150.0400.2700.0275873656346673956.5868_NADPHdehydrogenase
*195119___________ -1.54 -2.050.0030.0180.00511603467525465647606.6330_
196682___________ -1.20 -1.120.1140.0610.4297039758689627666.6791_
*19350____________ +1.21 +1.300.0010.0130.0024720157073615366.7234_20SproteasomecomponentY13
*195257___________ -2.99 -2.760.0000.0000.00011005836815398516.7685_sphingolipidlongchainbasekinase
*197231___________ +1.41 +1.460.0020.0050.0091523221478221736.8131_plasmamembraneironpermease
*197402___________ +1.86 +1.780.0000.0000.0003520265550625866.8562_potentiallyinvolvedinmeiosisandtranscriptionalsilencing
197662___________ -1.18 -1.240.0570.0870.0823874532873312796.9010_regulatorofTy1Transposition
*194225___________ +2.03 +2.070.0020.0080.0061617332785334936.483__
*194776___________ +1.31 +1.370.0000.0010.0012530333058346196.1105_zincfingertranscriptionfactoroftheLYS14family
193147___________ +1.25 +1.150.0050.0060.0321288716096148816.1657_conservedhypotheticalprotein
*196247___________ +1.29 +1.420.0000.0030.0012077326901294016.2199_DNApolymerasealphabindingprotein
19646____________ +1.03 -1.110.5660.8790.3342166682241981960196.2713_
193938___________ -1.27 -1.290.0670.0460.2342749621621213476.3225_
*196479___________ +1.26 +1.310.0010.0080.0023085738893403466.3715_SNAREbinding,latestageofsecretion
*194504___________ -2.17 -2.150.0010.0020.0024602221228214346.4196_alcoholdehydrogenase
192583___________ +1.26 +1.100.0220.0190.1041465118468161206.4684_peptidetransporter
*19213____________ +1.33 +1.450.0010.0040.0014055653863587666.5160_26Sproteasomeregulatorysubunit
*19323____________ +1.72 +1.810.0000.0010.0002295739489414386.5634_
*192173___________ +1.57 +1.680.0000.0010.0012903945519488166.6090_nuclear-cytoplasmictransport|negativeeffectorofPolIIIsynthesis
19670____________ +1.16 +1.220.0510.1650.0451755622028832139676.6563_sumoylationfactorassociatedwithkinetochorfunction
*196862___________ +1.32 +1.500.0010.0080.0012513733226377426.7011_conservedhypotheticalprotein
*192091___________ -3.32 -3.310.0000.0000.00022865468907691736.7464_subunitNUHMofNADH:UbiquinoneOxidoreductase
*194611___________ +1.57 +1.700.0000.0000.0004030063237685716.7910_ribose-phosphatepyrophosphokinase
195367___________ +1.30 +1.290.0070.0110.0231356617638175226.8356_helicaserequiredformitoticdiploid-specificrecombinationandrepair
197537___________ +1.13 +1.080.0410.0410.1131427116189154636.8788_
*192782___________ -1.46 -1.700.0060.0160.0126351843484373436.14___
199______________ +1.16 +1.130.0070.0130.0191305415171147626.507__hypotheticalprotein
19230____________ +1.02 +1.030.6890.4840.6961242112726128026.1122_hypotheticalprotein
191772___________ +1.12 +1.240.0120.0850.0131368215307169646.1678_conservedhypotheticalprotein
*196470___________ +2.36 +1.840.0070.0150.0193606085049664566.2214_alkylhydroperoxidereductase
192713___________ -1.05 -1.030.3020.1770.5281170811186114206.2730_
191725___________ +1.09 +1.040.2130.1240.4611212113196126436.3239_
193088___________ +1.09 +1.130.0350.1910.0281267313853143606.3733_hypotheticalprotein
193754___________ +1.23 +1.290.0030.0110.0071380617024178136.4212_secretedacidphosphatase
192740___________ +1.00 +1.100.1030.7220.0501223912255135206.4697_
192417___________ +1.07 +1.150.0100.0790.0111246113336142796.5177_
*193973___________ +1.02 -1.480.0180.3650.0123320633852224706.5649_conservedhypotheticalprotein
193417___________ +1.03 +1.020.4260.5250.2921673017288171086.6109_
192771___________ +1.18 +1.100.1380.1190.2222095724637231246.6581_rhoGTPaseactivatingprotein(GAP)
*191896___________ -1.69 -1.970.0050.0140.0123079418224156356.7025_
192076___________ -1.11 -1.110.0630.0990.0841884717038169076.7479_conservedhypotheticalprotein
194625___________ +1.13 +1.180.0040.0260.0051329314970157386.7924_transcriptionfactorIIA,smallchain
*197288___________ -2.75 -3.050.0000.0010.0004701017109154006.8370_
*196828___________ +1.48 +1.510.0060.0150.0151417221004213376.8803_proteinInvolvedinprocessingrRNAprecursorspeciestomaturerRNAs
Cachs1___________ -1.01 -1.040.6980.9180.445118641171611361Cachs1_
191009___________ +1.22 +1.200.0070.0140.0211544018783185366.219__
191935___________ +1.21 +1.160.0020.0060.0091309015860151936.831__hypotheticalprotein
191976___________ -1.00 -1.090.6250.4450.6263150631363288236.1408_thioredoxinII
193517___________ -1.08 -1.070.1120.0900.2252249520764209396.1950_conservedhypotheticalprotein
*192157___________ -1.71 -1.570.0010.0020.0086835039858435926.2471_
*191096___________ +1.54 +1.770.0010.0060.0011583424345280616.3001_chloridechannel,possiblyvoltagegated
*19132____________ +1.38 +1.610.0030.0160.0061397819241224686.3482_
*194250___________ -1.45 -1.820.0010.0070.0013066421140168806.3974_hypotheticalprotein
*19309____________ +1.77 +1.730.0000.0020.0013390459923585926.4447_allantoatepermease
192849___________ +1.81 +1.320.0700.0580.1805143949303306788036.4943_aquaporin
*196186___________ -1.47 -1.550.0020.0050.0044168228429269246.5407_hypotheticalprotein
*192262___________ -1.75 -2.150.0030.0080.0088912250935414846.5884_NADPH:quinonereductase|zeta-crystallin
*195103___________ +1.53 +1.690.0010.0040.0011579724101267656.6347_phosphoglyceratemutase
196698___________ +1.04 +1.090.1950.2760.1651381814379150976.6806_
*194438___________ +2.93 +3.280.0000.0000.00030852904971012566.7251_zinc-fingertranscriptionfactor

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
195244___________ +1.02 +1.020.4970.2630.9812871329213293576.7698_morphogenesischeckpointdependent
197245___________ +1.00 -1.040.6080.4780.5471583015867152576.8145_conservedhypotheticalprotein
197417___________ -1.16 +1.020.0940.0390.9388250827095168421036.8577_thiol-specificantioxidantprotein
*197676___________ -2.63 -3.300.0000.0020.0014868218510147746.9024_sorbitoldehydrogenase
*192457___________ +1.34 +1.190.0130.0110.0921891925393225306.34___
19736____________ +1.21 +1.120.0040.0050.0271283915584143416.526__subunitofactivationmediatorsubcomplexofRNApolymeraseIIholoenzyme
191373___________ +1.48 +1.380.0020.0040.0071398220729192486.1145_
194330___________ +1.20 +1.100.0090.0110.0401301815659143406.1696_
*193599___________ +1.52 +1.330.0040.0080.0181421221579188696.2230_
193635___________ +1.25 +1.200.0050.0090.0161556819464186686.2751_
*194330___________ +1.34 +1.360.0030.0070.0081756823469238666.3255_
*19846____________ +1.79 +1.810.0020.0040.0082710248560491216.3748_putativeserine/threonineproteinkinase
*194894___________ -2.10 -1.900.0010.0020.0023827118207201396.4230_similartodemethylmenaquinonemethyltransferase
194659___________ +1.32 +1.230.0040.0090.0111630321600200256.4710_pre-mRNAsplicingfactor
*194295___________ +1.42 +1.530.0040.0110.0101382919657211626.5190_
196152___________ -1.06 +1.090.3170.8320.1642466023312269816.5662_conservedhypotheticalprotein
192901___________ +1.19 +1.220.0140.0250.0341253514965153046.6120_
192760___________ +1.23 +1.220.0040.0120.0101675420620204576.6593_
*191881___________ +1.66 +1.910.0000.0000.0003117051657595986.7039_conservedhypotheticalmembraneprotein
192064___________ +1.11 +1.040.0810.0370.5701336414865139576.7491_conservedhypotheticalprotein
*197012___________ -1.68 -1.690.0010.0030.0033017417951178056.7938_mitochondrialribosomalproteinS24
197301___________ +1.09 +1.020.2820.1690.4921276013901129746.8383_
*196812___________ +2.33 +2.450.0010.0030.0031343431236329736.8819_dolichyl-P-mannose-proteinmannosyltransferase
Cafks2___________ +1.02 +1.030.3830.2480.515120211228812379Cafks2_
193336___________ +1.24 +1.040.0080.0050.3911203014900125446.239__hypotheticalprotein
191210___________ +1.10 +1.170.1850.3560.1292953832447344906.843__vacuolaraminoacidtransporter
*19454____________ +1.79 +2.020.0000.0010.0002818250542568336.1425_
191911___________ +1.05 +1.160.0840.4940.0463439135980398906.1967_
194068___________ +1.35 +1.240.0060.0070.0311317417839163936.2486_hypotheticalprotein
*194059___________ +2.08 +1.870.0020.0040.0061384628749258256.3015_
195184___________ -1.23 -1.070.1540.0810.4888508968980798856.3495_
194349___________ +1.22 +1.230.0080.0140.0231265015378155286.3994_
*195521___________ -1.23 -1.290.0170.0440.0266204450434482556.4463_IronSulfurAssembly
192476___________ +1.22 +1.210.0090.0190.0231574519134189776.4958_
*196202___________ +3.18 +3.510.0000.0000.0002305073336808246.5422_pathogenesisrelatedprotein,repressedbyTUP1protein4
192247___________ +1.05 +1.170.0980.1400.1151246813079146446.5899_conservedhypotheticalmembraneprotein
*191999___________ +3.49 +3.330.0000.0000.0002174875963723246.6361_hypotheticalprotein
194115___________ +1.03 +1.050.2640.1990.3491309013432137276.6821_hypotheticalprotein
194450___________ -1.01 -1.080.4570.8990.2501724817082160386.7263_zincfingertranscriptionfactor
*196966___________ +1.66 +1.590.0000.0010.0012243637316357866.7712_cholinekinase
197260___________ -1.13 +1.000.1250.0540.7863915234779392166.8160_similaritytoaldosereductases
*197433___________ +2.21 +2.920.0000.0010.0012475054719721746.8591_
195999___________ +1.19 +1.140.0300.0240.1371232214646140246.9039_
*194890___________ +1.58 +1.570.0040.0120.0071712326998268736.54___
19261____________ +1.08 +1.100.0230.0510.0371291413911142676.549__
193172___________ +1.00 +1.000.8630.8390.6611416214163141696.1163_
194697___________ -1.00 +1.020.6290.9550.3811248812481127326.1712_
191393___________ +1.04 +1.050.4430.4980.3201611216795169896.2245_mitochondrialcarrierprotein
194221___________ +1.02 -1.030.9290.9590.7391394814161134946.2766_orginrecognitioncomplexsubunit
192857___________ +1.07 +1.150.4430.2290.8791364814644156346.3275_
193460___________ +1.24 +1.410.0030.0100.0051366416994192786.3763_
*191281___________ +1.46 +1.450.0040.0140.0081592023290230466.4244_conservedhypotheticalprotein
*19577____________ +1.31 +1.290.0090.0230.0191993226173257406.4727_conservedhypotheticalprotein
*194282___________ +2.43 +2.810.0010.0030.0011561637974438796.5204_hypotheticalprotein
196137___________ -1.08 -1.140.0790.0720.1622207320383194276.5677_hypotheticalprotein
192888___________ +1.05 +1.170.0240.4940.0141372814430160416.6134_hypotheticalprotein
194239___________ +1.00 -1.010.3950.1960.9191202512037119326.6607_
*191868___________ +2.04 +2.070.0000.0040.0012144543794443266.7052_smallsubunitofribonucleotidereductase
193811___________ -1.05 -1.010.3050.2480.3451675016003166466.7506_GTPaseactivatingprotein
*197025___________ +1.70 +1.920.0020.0070.0031793330492344406.7951_transcriptionfactoroftheMADSboxfamily
*197316___________ -1.25 -1.280.0100.0180.0263174225412247556.8397_conservedhypotheticalprotein
*196800___________ +1.35 +1.640.0050.0230.0091476219947242086.8831_proteininvolvedinoxidativestress
Casmi1___________ -1.06 -1.070.1820.4070.117122601157611509Casmi1_
*19661____________ +2.62 +2.760.0000.0000.0001803147257497416.254__
*6862_____________ -1.35 -1.280.0090.0120.0364447433035347206.862__
19118____________ -1.09 +1.140.1470.0800.4544075237224465606.1443_oleatedelta-12desaturase
19692____________ +1.00 +1.080.8150.9680.5683171031786343396.1983_possibleperoxin
1999_____________ +1.20 +1.120.0170.0340.0331330015946149026.2501_
*193647___________ +1.21 +1.600.0090.0450.0121329816121212316.3030_componentofexocystcomplex
193963___________ -1.07 +1.010.3290.1670.7342701825323271646.3508_conservedhypotheticalprotein
192942___________ +1.18 +1.140.0090.0200.0221254814751143536.4007_
193180___________ -1.01 +1.000.7920.5510.8375511254613552766.4477_inositolpolyphosphate5-phosphatase
*192463___________ +1.28 +1.220.0170.0420.0292222028473270956.4972_RNApolIItranscriptioncofactor
196284___________ -1.12 -1.070.2170.1720.3044127936947386786.5434_signalrecognitionparticlebetasubunit
*194932___________ -5.59 -5.930.0000.0000.00020722637080349716.5912_mitochondrialtranslationelongationfactor
*191413___________ -2.06 -2.300.0010.0020.0027406835996322256.6382_regulatorofmitochondrialironaccumulation
194100___________ +1.21 +1.130.0120.0270.0251352916415153116.6838_
*19900____________ +1.62 +2.020.0030.0180.0051994132243403456.7276_
*196979___________ +2.00 +2.580.0000.0040.0011732534587446276.7725_hemolysin-likeproteinrequiredfornormalmitochondrialstructure
*197274___________ +1.61 +2.060.0020.0080.0041542124822317936.8174_
*197445___________ +3.78 +5.580.0000.0010.00018148686001013286.8605_peripheralvesiclemembraneprotein
195984___________ -1.01 -1.020.8050.6400.7081575715611154946.9053_conservedhypotheticalprotein
*19150____________ +1.48 +1.400.0000.0010.0032693239928376786.75___mitochondrialinnermembraneimporttranslocasesubunit
19916____________ +1.18 +1.180.0020.0050.0081651019442194576.569__conservedhypotheticalmembraneprotein
19115____________ +1.23 +1.120.0020.0030.0211250115422140596.1183_hypotheticalprotein
*19708____________ +1.57 +1.440.0010.0020.0041503923668216686.1728_spindlepolebodycomponent
*193757___________ -1.28 -1.630.0310.0500.0586369649936389746.2263_proteinassociatedwithmitochondrialATPsynthase
191144___________ +1.31 +1.170.0090.0100.0451268016656148206.2786_
*193618___________ +2.98 +4.200.0000.0000.00030104897851263806.3289_
*194361___________ +1.29 +1.250.0050.0080.0192082726869260476.3777_
*192211___________ -6.95 -5.170.0000.0000.00021289083062234115376.4256_hypotheticalprotein
*192117___________ -2.26 -2.090.0000.0010.0016368228169304826.4744_mitochondrialcarrierprotein
*194813___________ +1.58 +1.740.0000.0010.0004494671235780466.5219_GMPsynthase
19586____________ -1.02 -1.000.7470.8190.5141755017286175346.5694_ER-Golgitransportvesicleprotein,componentofcopII
195831___________ +1.04 +1.010.3990.2210.6831236912869124616.6147_hypotheticalprotein
*195788___________ -2.18 -2.000.0000.0000.0015952842730772978376.6622_
*19501____________ +1.81 +2.340.0010.0040.0011631429583382016.7069_
193826___________ +1.23 +1.210.0080.0230.0161771421819214556.7521_hypotheticalprotein
197038___________ +1.11 +1.060.0470.0280.2861233413733130676.7964_peripheralGolgiproteinrequiredforvacuolarproteinsorting
*197327___________ +1.38 +1.400.0010.0050.0042016627793281926.8408_inorganicphosphatetransport

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
196787___________ +1.23 +1.160.0060.0110.0231321716215153396.8844_14KDaproteinfoundonER-derivedvesicles
41959____________ +1.03 +1.020.3090.1990.4621212612446124264.1959_
19226____________ +1.32 +1.240.0090.0170.0251243616405154026.274__hypotheticalprotein
191809___________ +1.22 +1.080.8360.7560.6612453630032265416.882__
192638___________ +1.29 +1.200.0070.0080.0391315616917158216.1459_
19246____________ +1.03 +1.190.4160.9010.2222471625518292916.1996_
*192726___________ -1.16 +1.140.0150.0200.0473106226868353476.2518_plasmamembraneproteininvolvedinphosphatidylethanolaminebiosynthesisandotherprocesses
194524___________ +1.02 +1.030.7460.5470.7141514515491156046.3047_zincfingertranscriptionfactor
*19637____________ -1.24 -1.210.0120.0970.0123050124603251766.3524_succinatedehydrogenasesubunit
*194751___________ -1.26 -1.200.0170.0220.0533226025621268286.4021_mitochondrialribosomesmallsubunitcomponent
*192831___________ +1.46 +1.430.0000.0030.0013922857288559026.4492_DNA-directedRNApolymeraseIIIsubunit,HMG-like
*193475___________ +6.03 +5.200.0000.0000.000455062742242366676.4984_
194686___________ +1.18 +1.210.0510.0510.1221279715143154606.5450_conservedproteinwithsimilaritytomitochondrialaldehydedehydrogenase
*197550___________ -1.23 -1.300.0150.0200.0473530612869022718086.5927_
191427___________ +1.30 +1.200.0020.0040.0121694221975203846.6396_conservedhypotheticaltransporter
194086___________ -1.19 -1.190.0050.0100.0142704922690226886.6850_putativetyrosinephosphatase
19886____________ -1.06 -1.170.4220.9920.2246835264296581986.7291_
*196991___________ +1.37 +1.490.0000.0010.0003194243707475806.7737_20Sproteasomesubunit|multicatalyticendopeptidase
*19939____________ +1.73 +1.970.0000.0000.00054486940981076046.8188_helicase
197457___________ +1.25 +1.170.0300.0210.1801588819917186546.8617_hypotheticalprotein
195971___________ +1.02 +1.010.6060.3460.9651205312303121596.9065_
*19922____________ +2.56 +2.060.0000.0010.00147043120497967056.98___
*192026___________ +1.62 +1.580.0040.0060.0162143834668339576.591__
191434___________ +1.08 +1.090.0240.0620.0331269013757138416.1203_
191177___________ +1.02 +1.020.6990.7290.4901346213756136826.1744_
19470____________ +1.18 +1.190.0170.0680.0201521317894181666.2280_
191490___________ -1.01 +1.020.6880.8310.4491246612345127126.2803_
193659___________ +1.15 +1.060.1380.1130.2371664619204176156.3302_conservedhypotheticalprotein
195722___________ +1.05 +1.070.2190.2860.1871355214250144686.3798_
*192614___________ +1.70 +1.560.0010.0030.0041953333130305316.4271_GtTP-bindingproteinoftherassuperfamilyinvolvedinbudsiteselection
192101___________ +1.08 -1.310.2280.5000.1363557438305272326.4760_coiled-coilmembraneprotein
194143___________ -1.01 +1.110.0900.7270.0441458414468162256.5236_
192982___________ -1.01 +1.010.3770.9180.1971247512344125846.5707_involvedinautophagy
192478___________ -1.03 -1.010.6160.4030.6971202011661119166.6160_
195804___________ +1.04 -1.040.9840.9090.9132355324516226886.6638_5-oxoprolinase|hydantoinutilizationproteinA
19487____________ -1.05 -1.040.5080.6250.3341292412319124276.7084_N-acetylglucosaminyl-phosphatidylinositol(GPI)biosyntheticprotein
193841___________ +1.03 +1.030.3440.2600.4001246812895128466.7537_
195031___________ +1.08 +1.140.0630.1020.0831668617947190206.7978_putativereponseregulatortwo-componentphosphorelaygene
197341___________ +1.10 +1.060.1010.0970.1731510516608160826.8422_conservedhypotheticalprotein
196776___________ +1.03 +1.000.7240.4810.8031231412731123266.8855_translationinitiationfactoreIF2B
42408____________ -1.06 -1.060.2700.3370.2171181411182111894.2408_
*196492___________ +3.72 +4.280.0000.0000.0001781166213762386.289__ser/thrproteinkinase
193195___________ +1.12 +1.170.0020.0100.0051319314839154676.908__
*192779___________ +2.01 +2.210.0010.0030.0021487329847328946.1476_hypotheticalprotein
*191053___________ +1.47 +1.600.0010.0080.0022105131004336606.2009_negativeregulatorofCOPIIvesicleformation
192748___________ +1.42 +1.340.0020.0070.0051235817536165816.2536_transcriptionfactorinvolvedinargininemetabolism
194800___________ +1.18 +1.290.0060.0340.0081436816962185486.3059_Rim101pactivatingprotein
*191499___________ +1.56 +1.850.0010.0040.0033552355267657926.3544_
*195820___________ +2.99 +3.640.0000.0010.0011253837546455916.4039_GABA-specifictransportprotein
*195636___________ -6.10 -5.510.0000.0000.00026636124368764837846.4506_
*194512___________ +1.71 +1.620.0020.0070.0071642828146266246.4999_leucinerichrepeatgenefamilyprotein
*193733___________ -3.74 -5.320.0000.0020.00020952256043393486.5463_
195155___________ +1.07 +1.050.1910.1620.2631241813251130016.5943_
*191552___________ -4.44 -5.540.0000.0010.00014441032536260636.6408_
196715___________ +1.03 +1.020.9050.8920.7101278413118130986.6864_hypotheticalprotein
19872____________ +1.02 +1.030.4640.4500.3701286213108132686.7305_hypotheticalprotein
*193013___________ +2.12 +2.330.0000.0020.0012715457582632476.7750_septin
19952____________ +1.09 +1.110.0380.0960.0441379315037153636.8202_
*195395___________ +1.27 +1.380.0040.0170.0081733821958239096.8630_
*195959___________ +1.27 +1.480.0010.0090.0021764822347261326.9078_nuclearandnucleolarproteinwithpossibleroleinribosomebiogenesis
191841___________ +1.30 +1.260.0030.0040.0161274316585159966.119__
191009___________ +1.28 +1.260.0030.0050.0121272616247160046.611__hypotheticalprotein
191831___________ +1.25 +1.160.0030.0070.0131226615387142026.1221_hypotheticalprotein
194688___________ +1.24 +1.210.0040.0110.0091344716650163026.1767_
*193353___________ +1.56 +1.180.0060.0040.2223315251813390676.2295_possiblecomplexIintermediateassociatedprotein
194404___________ +1.14 +1.100.0110.0120.0571272214534139696.2824_hypotheticalprotein
195039___________ +1.48 +1.360.0010.0020.0031555823087211836.3316_rRNAprocessingprotein
*192563___________ +1.47 +1.560.0010.0040.0042717239904423926.3812_U4/U6snRNA-associatedsplicingfactor
*193539___________ -5.29 -3.890.0000.0000.000449585849801154606.4285_conservedhypotheticalprotein
195618___________ -1.08 -1.060.2270.2550.2173277530394308696.4777_vacuolarproteinsortingassociatedprotein
193865___________ +1.24 +1.340.0050.0160.0091337016640179226.5254_
191254___________ +1.14 +1.060.1260.0680.4423357338199355316.5721_componentofCOPIIcoatofER-golgivesicles
192495___________ +1.28 +1.280.0040.0090.0101557319930199746.6176_1,3-beta-glucansynthase|targetforechinocandinantifungaldrugs
192963___________ +1.06 +1.030.9070.9000.7122655328170273096.6653_transcriptionalregulatoryprotein
191473___________ +1.06 +1.040.1920.1680.2561205912819125506.7101_
196566___________ +1.02 +1.030.6750.4230.8251337413660137356.7554_hypotheticalprotein
195017___________ +1.07 +1.160.0100.0480.0131849419812214456.7992_ureatransportprotein
*197118___________ -2.40 -2.430.0000.0000.0008151534024335676.8435_adenylatekinase
*196760___________ +1.61 +1.900.0020.0070.0041524424503289116.8871_negativeregulatorofearlymeioticexpression,requiredforgrowthatalkalinepHandinhighconcentrationsoflithiumchloride
42686____________ +1.04 +1.040.2400.2480.2401485515429154724.2686_
194650___________ +1.32 +1.200.0030.0040.0231363417984163746.304__
693______________ +1.35 +1.130.0040.0050.0281290817468146456.930__
*192803___________ -1.56 -1.120.0010.0010.0792317721487622065336.1494_coprophyrinogenoxidase|hemebiosynthesis
194465___________ +1.28 +1.190.0060.0100.0261546219726183856.2032_hypotheticalprotein
19801____________ +1.50 +1.350.0060.0090.0281311619635177096.2550_telomereTTAGGGrepeat-bindingfactor
194555___________ +1.13 +1.090.0530.0300.3071261614228137056.3074_agglutinin-likeprotein4
*192458___________ +1.47 +1.320.0010.0040.0051908328011251756.3560_
193924___________ +1.22 +1.060.0130.0080.2271304015847138106.4052_conservedhypotheticalprotein
196211___________ -1.16 +1.000.1660.0980.4076624856875665146.4523_conservedhypotheticalprotein
*194208___________ +1.66 +1.580.0010.0030.0031700328206269466.5013_recombinationandDNArepairprotein
*193749___________ +5.79 +4.980.0000.0000.0001380237993656873286.5478_
195139___________ +1.08 +1.220.0740.1420.0784518848632550036.5959_hypotheticalprotein
191565___________ +1.01 -1.060.3220.5750.1921868818918175896.6422_dihydrouridinesynthaseoftRNA
*196729___________ +1.27 +1.250.0010.0020.0052784435373348006.6878_TIP120protein[Homosapiens
196933___________ +1.01 +1.000.3670.1820.8591394614016139656.7319_ResistanttoRapamycinDeletion2
193027___________ -1.07 -1.170.1350.7580.0664117038578353076.7764_generalRNApolymeraseIItranscriptionfactor
*19967____________ -1.31 -1.180.0130.0120.0783013722984256436.8216_mitochondrialnuclease
*195410___________ +1.51 +1.480.0010.0030.0031639424750241866.8646_possibleroleduringmitosis
*195943___________ -1.43 -1.370.0040.0060.0163054621396222996.9094_conservedhypotheticalprotein
195064___________ +1.12 +1.130.0130.0360.0211234813861139466.134__

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
191021___________ +1.07 +1.070.0610.0960.0821210912976129216.642__leucinerichrepeat
193173___________ +1.05 +1.080.0560.3140.0361248413046135006.1240_secretoryprotein
193290___________ +1.06 +1.070.0980.1400.1131213512869130046.1780_NADH:ubiquioxidoreductase
191961___________ +1.01 +1.030.6680.7870.4391219112291125256.2315_conservedhypotheticalprotein
194964___________ +1.00 -1.020.9450.9520.7731234812410120606.2841_conservedhypotheticalprotein
19705____________ +1.02 +1.000.7110.4380.9921221712464122536.3329_histoneacetyltransferase
195288___________ -1.20 -1.250.0320.0690.0462157617918173116.3827_Zn-containingalcoholdehydrogenase
19292____________ +1.00 -1.020.9890.9120.9371344413455131616.4300_
192681___________ -1.04 +1.010.7550.4920.9001193111486120126.4791_ribonuclease,T2family
196547___________ +1.10 +1.120.0530.1640.0471460016067164076.5267_hypotheticalprotein
191659___________ -1.03 -1.030.3260.3560.2691236511988119526.5734_glycosyltransferase
195764___________ -1.04 -1.060.1530.2850.1191224611723115896.6194_antiviralprotein
192951___________ -1.03 -1.090.3070.2910.2942502124313228776.6665_homoserinedehydrogenase
191459___________ -1.02 -1.040.5130.3950.4921766917273169266.7114_carboxylmethylesterase|ribosomalproteinofthesmallsubunit,mitochondrial
196581___________ +1.05 +1.100.1060.2540.0821706817994188146.7569_conservedhypotheticalprotein
*195004___________ +1.27 +1.480.0010.0080.0021373017423202986.8005_DNA-dependentATPaseoftheSnf2pfamily
197105___________ -1.05 -1.040.2040.1030.5991274812122122936.8448_cyclin-dependentproteinkinaseinhibitor
196747___________ +1.09 +1.180.0700.0630.1571594817345187556.8885_
42801____________ +1.00 -1.020.9930.9220.9651226012290120544.2801_
*1971271__________ -1.20 -1.230.0430.1090.0473802931734309006.321__NA
19183____________ +1.15 +1.140.0160.0490.0221279614762146016.945__imidazoleglycerol-phosphatedehydratase
191818___________ +1.24 +1.130.0090.0180.0231251815571140996.1510_
193586___________ +1.27 +1.160.3420.5910.2031288416378149356.2046_conservedhypotheticalprotein
19109____________ +1.08 +1.140.0370.1250.0361281413889145946.2566_
19451____________ +1.12 +1.260.0120.0260.0251336115017167906.3088_highcopysuppressorofacyclicAMP-dependentproteinkinasemutant
192209___________ +1.36 +1.350.0030.0080.0101264517208170696.3575_iontransportprotein
194670___________ +1.15 +1.170.0110.0420.0161338615412156586.4065_
194373___________ -1.02 -1.120.1770.2330.1662114420673188716.4538_riboflavinkinase
193328___________ +1.10 +1.090.0460.0670.0761308914385142126.5026_transcriptionalregulatorofhyperosmoticresponse
196302___________ +1.05 +1.030.1260.1180.1951270613309131466.5496_
192034___________ +1.05 +1.020.5090.3980.4811209512737123686.5973_hypotheticalprotein
191636___________ +1.01 +1.020.7130.4600.8352220822397225496.6436_pheromoneresponsepathwayprotein
*195653___________ -7.50 -8.210.0000.0000.00013477021796221641756.6893_F1F0-ATPasecomplex,F1betasubunit
196948___________ +1.03 +1.010.8410.6260.8161954020140196806.7334_transmembraneCa2+transporter
193042___________ +1.06 +1.070.1960.2360.1881223412940130546.7779_hypotheticalprotein
193230___________ +1.12 +1.080.0500.0540.1101262714137136416.8230_RHOproteinsignaltransduction
195425___________ -1.05 -1.020.3020.1410.9337451971099728696.8661_conservedhypotheticalprotein
195929___________ -1.02 +1.000.9250.8130.7951224412006122776.9108_conservedhypotheticalprotein
193102___________ +1.31 +1.180.0020.0030.0161713122356202526.148__
194403___________ +1.24 +1.180.0030.0070.0121308616247154586.656__
192650___________ +1.29 +1.230.0040.0110.0111315717022161196.1259_
*192167___________ +1.62 +1.660.0010.0030.0022113834339350726.1804_conservedhypotheticalprotein
*191648___________ +1.21 +1.290.0030.0090.0072145026018276556.2332_DNArepairprotein
19929____________ +1.13 +1.060.0660.0480.2101329814966140456.2859_hypotheticalprotein
194647___________ +1.37 +1.340.0030.0070.0111365418764182616.3344_partialCCAAT-bindingtranscriptionfactor
*194883___________ +1.60 +1.740.0000.0010.0003053448928530556.3842_
194474___________ +1.15 +1.090.0130.0120.0801586818291173746.4313_conservedhypotheticalprotein
*19281____________ +1.28 +1.340.0010.0030.0022640333717354566.4811_
*193009___________ +1.29 +1.440.0010.0080.0022088426879301726.5280_hypotheticalprotein
*193583___________ +1.70 +1.900.0000.0010.0002561643575487776.5746_Ran-GTPase-bindingproteininvolvedinnuclearexport
196597___________ +1.01 -1.000.8100.7290.6381505615146150506.6209_hypotheticalprotein
*194532___________ -1.30 -1.080.0220.0130.2515433841948502546.6678_conservedhypotheticalprotein
191445___________ +1.29 +1.290.0040.0090.0141324917136170456.7128_regulatorofTy1Transposition|EstablishesSilentChromatin
196037___________ +1.20 +1.190.0030.0070.0111538718429183636.7581_conservedhypotheticalprotein
194988___________ +1.06 +1.060.1040.1030.1671435715281151906.8021_hypotheticalprotein
*197092___________ -1.53 -1.460.0020.0070.0047133846705489796.8461_conservedhypotheticalprotein
*197549___________ -1.27 -1.080.0230.0170.1482821622231260956.8897_dolichyl-phosphate-mannose-proteinmannosyltransferase
42876____________ +1.17 +1.100.0210.0370.0411201114087132494.2876_
194466___________ +1.23 +1.150.0170.0230.0521228615155141676.338__potentiallyinvolvedinpalmitoylationandlocalizationofsmallGTPases
193469___________ +1.25 +1.150.0080.0140.0261455918143166896.961__
192818___________ +1.36 +1.250.0040.0070.0221406119056175566.1524_
62068____________ +1.31 +1.150.0060.0080.0361286116804147336.2068_
194867___________ +1.32 +1.080.1450.0610.9801434018934155426.2583_
191309___________ +1.20 +1.150.0070.0090.0411471217702169506.3104_
*192758___________ +2.72 +2.710.0000.0000.0002768675326751576.3590_
*191959___________ -1.26 -1.120.0020.0030.0193176625186283496.4080_conservedhypotheticalprotein
*1953_____________ +1.66 +1.760.0010.0020.0022321638651408856.4553_U2AFsplicingfactorsmallsubunit
191964___________ +1.10 +1.090.0590.0390.2401232813621133996.5039_
*196317___________ +1.76 +1.820.0000.0000.0003140255190572516.5510_5'-phosphoribosylformylglycinamidinesynthetase
192046___________ +1.04 +1.020.1060.0500.5561291313437131086.5985_acetyl-CoAC-acyltransferase,peroxisomal|fattyacidbeta-oxidation
191620___________ +1.15 +1.030.0560.0270.4661314815126135886.6452_hypotheticalprotein
*195665___________ -1.23 -1.150.0100.0100.0643187825929278056.6905_conservedhypotheticalprotein
*194858___________ +1.33 +1.450.0100.0200.0251299617297189036.7353_
193054___________ +1.20 +1.130.3060.1750.5542034524447228906.7791_26Sproteasomesubunitofendopeptidase
*193243___________ -1.16 -1.280.0100.0180.0282596222369202866.8243_signalrecognitionparticle
*195437___________ +3.44 +5.210.0000.0000.000529541820732761266.8673_DL-glycerol-3-phosphatase
195915___________ +1.04 -1.010.4230.2150.8861339013929133136.9122_ureaactivetransportprotein
196382___________ -1.03 -1.040.4620.4340.3791172611332113046.13___
192721___________ +1.22 +1.150.0070.0100.0321271015443146696.676__
*19333____________ +2.24 +1.860.0010.0020.0041277428647237466.1275_
192885___________ +1.32 +1.170.0240.0160.2101426518849166786.1820_DNA-directedDNApolymerasealpha,DNAprimasesubunit
192538___________ -1.06 -1.060.1140.2310.0961167411004110016.2347_
193700___________ +1.05 +1.040.9620.8050.9572062721602215176.2877_mitochondrialoutermembranespecializedimportreceptor
196498___________ -1.10 -1.080.0670.1020.0891158610506107246.3362_
*192392___________ +2.28 +1.780.0010.0030.0042612959553465116.3856_hypotheticalprotein
*193402___________ -1.02 -1.270.0160.5240.0099271590725728156.4329_conservedhypotheticalprotein
*19605____________ +1.21 +1.110.0100.0110.0531570419056174936.4826_hypotheticalprotein
*191361___________ -1.23 -1.300.0290.0540.0496010248941463176.5293_
*193568___________ +1.54 +1.330.0010.0030.0052036331297270346.5761_conservedhypotheticalprotein
196612___________ -1.05 -1.100.2550.7810.1293215730652292656.6225_
194544___________ +1.12 +1.060.0170.0130.1331481016532157686.6690_hypotheticalprotein
*196877___________ +1.54 +1.450.0050.0070.0271137781749221649186.7140_
*196049___________ +1.68 +1.400.0020.0040.0132474741606345646.7595_
*197136___________ +1.90 +1.990.0010.0030.0021676231860332766.8034_
*197078___________ -1.28 -1.600.0010.0110.0024316533619270466.8475_conservedhypotheticalprotein
197563___________ +1.16 +1.050.5380.5030.4243808244313401576.8911_geranylgeranyltransferasetypeIIbetasubunit
43071____________ -1.00 -1.040.2700.9130.1341193511878114854.3071_
*194257___________ +2.11 +1.800.0010.0020.0041582033304285136.358__
196243___________ +1.28 +1.220.0040.0080.0121286716515157376.983__
*192454___________ +1.91 +1.630.0010.0020.0031721632838280606.1541_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194735___________ +1.06 +1.050.1820.0790.9681846019546193556.2086_putativeornithinecyclodeaminase
19131____________ +1.42 +1.400.0010.0050.0021500421313210676.2601_hypotheticalprotein
*191707___________ +1.97 +1.830.0000.0010.0011603631545293436.3120_hypotheticalprotein
192788___________ +1.19 +1.090.0160.0100.2081329615789144516.3605_
*191755___________ +1.31 +1.240.0040.0070.0132931638303363776.4094_transcriptionalrepressorcontainingaSETdomain
*64566____________ -1.77 -1.940.0000.0000.000179323101091922336.4566_
195861___________ +1.06 +1.020.1200.0690.3842353224870240216.5053_cellwallsynthesisprotein|cellwallbeta-glucanassembly
*196336___________ +1.24 +1.270.0050.0180.0091978224606251976.5526_
*196458___________ +1.45 +1.580.0000.0020.0011983328817312376.6001_conservedhypotheticalprotein
193440___________ +1.17 +1.200.0040.0110.0111336115612160986.6465_putativetransporter
193126___________ -1.22 -1.090.0570.0520.1456605354231604506.6919_cytoplasmicchaperoninoftheCctringcomplex
*194843___________ +3.17 +3.160.0000.0000.0002205569963697026.7368_conservedhypotheticalprotein
*193066___________ +2.01 +1.880.0000.0010.0003569271891672146.7803_endo-1,3-beta-glucanase
*193256___________ +1.71 +1.690.0070.0140.0191395623859236546.8257_
195449___________ +1.15 +1.040.2550.1270.6685185459854540546.8685_peroxisomalmembraneprotein
195902___________ -1.01 -1.040.5790.7680.3611190911752114086.9135_GTP-bindingproteinoftheRasfamily
*19173____________ +1.83 +1.490.0010.0020.0071618829646241326.51___
19255____________ +1.39 +1.310.0050.0080.0181333318588174976.693__
*191990___________ +1.63 +1.470.0010.0020.0041635826646239776.1292_SortingNeXin
194636___________ +1.24 +1.150.0070.0070.0521329316435153166.1838_hypotheticalprotein
*19267____________ +1.93 +2.030.0000.0010.0012631950767532996.2361_
192882___________ +1.51 +1.220.0040.0060.0311231118588150006.2894_highlyconservedhypotheticalprotein,putativepurinepermease
*195059___________ +1.89 +1.850.0000.0000.0002361444618437796.3377_
1963132__________ +1.23 +1.090.0110.0080.1171270115612138456.3874_NA
192199___________ -1.02 -1.140.0400.2350.0291982519435174126.4342_inorganicphosphatetransporter
191720___________ +1.18 +1.100.0140.0140.0661489617550164386.4840_conservedhypotheticalprotein
65307____________ +1.16 +1.060.0460.0250.3561231114254130576.5307_
196345___________ +1.19 +1.170.0120.0160.0441860822134217146.5774_translationinitiationfactoreIF3
*196103___________ +1.74 +1.710.0000.0010.0011784430959305636.6238_similartoproteininvolvedinsporulation
*19814____________ +1.66 +1.540.0010.0020.0041700028143261516.6705_transcriptionalregulatorofmultipleaminoacidpermeases
196893___________ +1.21 +1.180.0170.0460.0251566418917184366.7156_
196063___________ +1.02 +1.010.6060.3480.9242081621173210456.7607_deubiquitinatingenzyme
*197152___________ -1.60 -1.360.0010.0020.00510421665186767516.8052_cysteinesynthase
*197064___________ +1.84 +2.210.0000.0000.0004249678000938916.8489_glutaminyl-tRNAsynthetase
*197577___________ -2.60 -2.590.0000.0000.0007856030251303526.8925_proteininvolvedinmaturationofCOX1andCOBmRNA
PHR1_____________ +1.04 +1.020.3820.2300.573122931278312535PHR1___
191698___________ +1.15 +1.100.0560.0370.2311204113843132296.375__
192549___________ +1.20 +1.120.0130.0130.0741504618106168736.1005_
194972___________ +1.05 +1.030.2390.1600.3941256813258129416.1555_
193412___________ +1.05 +1.030.5070.2780.8411228012876125956.2101_lipaseinvolvedinautophagy
194157___________ -1.13 -1.170.0140.0340.0251823416185156086.2621_peroxisomal2,4-dienoyl-CoAreductase
*191161___________ +1.39 +1.290.0020.0040.0081802425062233156.3136_
192440___________ +1.14 +1.060.0540.0280.3881193413596126026.3619_cullin,ubiquitinligaseactivity
192587___________ +1.10 -1.010.0640.0270.7991243213710123426.4111_
192812___________ -1.03 +1.020.3580.1930.6711900118476193546.4581_nitrosoguanidineresistance|drugtransporter
195605___________ +1.05 +1.050.1910.1000.5361705517830178766.5067_conservedhypotheticalprotein
192307___________ -1.18 -1.060.0100.0070.1932698422849254086.5543_polyadenylationfactorIsubunit2
19730____________ -1.03 -1.040.3860.7170.2171237012024118526.6013_GTPaseactivatingprotein(GAP)forRho
193667___________ +1.10 +1.010.0930.0390.8671193013116120866.6478_kinesin-relatedprotein
193114___________ +1.49 +1.300.0020.0040.0121308519536170656.6931_pseudouridylatesynthase
*194828___________ -1.60 -1.350.0010.0030.0056591341166486466.7383_hypotheticalprotein
196437___________ +1.03 -1.020.5110.2730.9771266213015124666.7817_componentofanaphase-promotingcomplexrequiredformitosisandRNAsynthesis
193269___________ +1.02 +1.010.4380.2300.8201232612628124326.8269_
*195465___________ +1.17 +1.220.0020.0100.0032271026458277106.8701_conservedhypotheticalprotein
195887___________ +1.22 +1.200.0060.0110.0191744721365209496.9150_nuclearporeprotein
19151____________ +1.05 +1.060.1410.1420.1891264413335133906.76___
*191236___________ +1.80 +1.460.0030.0050.0151470326424214506.710__
191507___________ +1.56 +1.330.0010.0030.0061427522303189976.1307_AntagonistofMEN(MitoticExitNetwork)|chromosomestability
191529___________ +1.27 +1.160.0510.0260.4261320316766152946.1856_hypotheticalprotein
*192021___________ +4.99 +4.710.0000.0000.000817604077183853576.2378_
*19171____________ +1.69 +1.410.0010.0030.0091705328859239846.2907_DEADboxRNAhelicase
191523___________ +1.23 +1.120.0060.0060.0531496018430167926.3390_
191334___________ +1.49 +1.360.0060.0110.0201413221069191986.3887_hypotheticalprotein
*195507___________ +1.32 +1.280.0080.0260.0142783636698355776.4355_rRNAprocessing
*195782___________ +1.20 +1.400.0060.0340.0084626855660649386.4854_phospholipase
196160___________ -1.09 -1.120.2670.9200.1321167410741104356.5319_
196360___________ +1.09 +1.020.1030.0480.5971232813386125726.5789_conservedhypotheticalprotein
196086___________ -1.14 -1.140.0330.1030.0351169310247102826.6255_2-isopropylmalalatesynthase
19829____________ -1.12 -1.140.0100.0370.0151167410386102836.6720_serine/threonineproteinkinase
196906___________ -1.22 -1.140.0090.0140.028121529989106986.7170_WDrepeatproteinthatinteractswiththetranslationalmachinery
196076___________ -1.17 -1.130.0100.0210.023116749937102876.7620_involvedinendosometogolgiproteintransport
197165___________ -1.15 -1.140.0060.0160.0141194810385104966.8065_hypotheticalprotein
197052___________ -1.16 -1.160.0190.0360.0381230210648105746.8501_phosphatidylinositolphosphatephosphatase
197592___________ -1.18 -1.130.1760.7280.0881243510534110236.8940_long-chainfattyacid--CoAligaseandsynthetase4
*1997_____________ +1.81 +1.780.0010.0020.0021496227034265656.389__
61028____________ +1.14 +1.120.0200.0200.0801221513913136986.1028_
193491___________ +1.14 +1.080.0360.0300.1411220213880131576.1571_
*192017___________ +2.47 +1.940.0010.0030.0051510237297293016.2115_RNApolymeraseIalphasubunit
19716____________ +1.14 +1.120.0250.0230.1071257014299141296.2637_similartopore-formingbacterialSepticolysin
*194716___________ +3.27 +2.640.0000.0000.0002647086531698826.3152_NADP-glutamatedehydrogenase
19756____________ +1.16 +1.060.0130.0100.1211253814519133426.3635_secretedaspartylproteinase7
195556___________ +1.11 +1.110.0620.0840.0961350214992150246.4126_hypotheticalprotein
194757___________ +1.28 +1.320.0030.0110.0071828023313242046.4598_nucleararchitecturerelatedproteinwithhomologytohumanNarf(NuclearprelaminARecognitionFactor)
*191233___________ +1.60 +1.640.0000.0010.0012993948028491016.5084_amidophosphoribosyltransferase
192676___________ +1.05 +1.060.2070.1950.2432785729116294496.5558_RNApolymeraseIIelongatorassociatedprotein
196267___________ +1.19 +1.100.0590.0490.1641251814851137086.6026_conservedhypotheticalprotein
*19422____________ +2.74 +2.570.0010.0040.0032354264430604606.6491_
193098___________ +1.14 +1.080.0380.0280.1681323015065143416.6947_RNAhelicase-relatedproteinrequiredforpre-mRNAsplicing
193986___________ +1.08 +1.020.1790.0780.8671270713680129876.7398_
*196422___________ +1.25 +1.310.0130.0450.0194489056249586536.7832_sulfonylureaherbicidesensitivity|partofanextracellularaminoacidsensor
193284___________ +1.02 -1.000.5870.3900.6561321613525131946.8284_hypotheticalprotein
*197466___________ +1.75 +1.910.0000.0030.0011658829059316206.8717_
*195871___________ +1.88 +1.710.0050.0100.0161746832759298666.9165_
192454___________ +1.34 +1.210.0050.0060.0311289617236155766.104__
192859___________ +1.28 +1.160.0050.0070.0301412218009164086.731__
192229___________ +1.41 +1.280.0020.0040.0141264917814161876.1322_zinc-fingerprotein
193484___________ +1.40 +1.160.0040.0040.0701396419593162626.1871_signalrecognitionparticlereceptor
195285___________ -1.42 -1.410.1120.2290.0944535131843322216.2391_flavodoxin
*195746___________ +1.99 +1.750.0050.0110.0151303925986227846.2925_alanyl-tRNAsynthetase
195124___________ +1.31 +1.210.0030.0050.0191289516840155906.3408_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
19414____________ +1.31 +1.170.0050.0060.0351318417265154316.3901_mitochondrialribosomesmallsubunitcomponent
*193508___________ -1.27 -1.450.0020.0090.0053846330264265916.4368_hypotheticalconservedprotein
*192994___________ -1.41 -1.160.0070.0100.0272300391627591978526.4871_ribosomalprotein
*191588___________ -1.61 -1.560.0000.0000.0006367939491407636.5332_conservedhypotheticalprotein
19993____________ +1.11 +1.060.0910.0470.4301331314770140606.5805_conservedhypotheticalprotein
*19395____________ -2.04 -2.640.0010.0040.002241815211855919168326.6269_enolaseI
19522____________ -1.12 +1.010.1740.0810.6895714150919575696.6734_mitochondrialATP-dependentprotease
*196919___________ +1.61 +1.720.0010.0030.0022156034774370766.7183_hypotheticalprotein
*196527___________ +1.77 +1.910.0000.0000.0004198274436803536.7633_pheromone-regulatedmembrane
*197181___________ -1.27 -1.130.0080.0100.0373442827131305636.8080_
*197354___________ +1.20 +1.150.0090.0120.0362654831835306076.8514_longevity-assuranceprotein
*197604___________ +1.51 +1.470.0000.0010.0021999030160293256.8952_targetingcomplex(TRAPP)componentinvolvedinERtoGolgimembranetraffic
19715____________ +1.05 +1.030.3300.1880.5801197712522122786.409__hypotheticalprotein
195614___________ +1.01 -1.040.2810.3800.2082159021786207176.1048_
193071___________ +1.15 +1.060.0300.0250.1351234014195130556.1590_
193663___________ +1.07 +1.030.1040.0490.5761229213205126596.2134_
1918_____________ +1.05 +1.050.4150.2120.8671638017276172766.2651_inosine-5'-monophosphatedehydrogenase|guanosinenucleotidebiosynthesis
194320___________ +1.14 +1.060.0580.0760.0951248814279132686.3172_hypotheticalprotein
194190___________ +1.02 +1.000.9140.7430.8421454214863145866.3647_similartodnaJchaperones
195378___________ +1.02 +1.020.6730.5550.5671949619880198016.4140_20SproteasomesubunitYC7ALPHA/Y8
194310___________ +1.03 +1.030.5380.4740.4461216412542124936.4615_hypotheticalprotein
*196117___________ +1.10 +1.300.0040.0510.0052687629624350586.5098_membraneproteinsimilartoauxineffluxcarrier
192335___________ +1.05 +1.000.4540.2650.6701493715611149846.5573_highlyconservedhypotheticalprotein
196277___________ -1.00 -1.030.2230.1160.5741180011772114546.6037_
19437____________ -1.05 -1.060.1750.1700.2181327412617125516.6505_
195174___________ +1.14 +1.130.0140.0190.0471818920699206106.6962_TFIIDsubunit|RNApolymeraseIItranscriptionfactor
193999___________ +1.01 -1.000.5350.3960.5321592816012158706.7412_conservedhypotheticalprotein
196405___________ -1.00 -1.010.5830.3620.7231264812648125526.7849_conservedhypotheticalmembraneprotein
195308___________ -1.03 -1.100.0520.5540.0281432813945130326.8297_hypotheticalprotein
197481___________ -1.17 -1.190.0620.0750.1062474821071207356.8733_malatedehydrogenase
19164____________ -1.08 -1.080.0770.1660.0731190211027110646.157__
6749_____________ +1.32 +1.210.0040.0070.0181276816905153946.749__
191341___________ +1.60 +1.320.0030.0040.0231377922057181526.1343_serine/threoninekinase
*191575___________ +1.25 +1.150.0480.0280.2932838535532326426.1887_
194570___________ +1.31 +1.160.0020.0020.0171594620814185296.2406_hypotheticalprotein
191206___________ -1.12 -1.110.0180.0530.0251169810468105686.2940_
192187___________ +1.38 +1.290.0050.0100.0151395719308179706.3423_tunicamycinresistanceprotein|UDP-N-acetylglucosamine-1-phosphatetransferase
192509___________ +1.25 +1.110.0140.0100.1271283915999142596.3914_hypotheticalprotein
*192871___________ -3.44 -5.260.0000.0000.0006044681759201149826.4380_succinatedehydrogenase
191324___________ -1.22 -1.100.0120.0140.054116719599106236.4886_structure-specificnucleaseofthenucleotideexcisionrepairosome
191576___________ -1.14 -1.110.0360.0760.0491171710268105926.5344_hypotheticalRING-fingerprotein|homologtohumanbreastcancer-associatedproteinBRAP2
196369___________ -1.17 -1.170.0060.0260.0091285911009110346.5822_
195092___________ -1.18 -1.130.0070.0170.016116569919103396.6284_hypotheticalprotein
19536____________ -1.18 -1.150.0080.0180.018116729879101926.6748_TFIIDandSAGAsubunit
193301___________ -1.14 -1.140.0090.0240.0181158110139101276.7196_F-boxproteininvolvedinsulfurmetabolism
196512___________ -1.18 -1.110.0230.0330.0571198010120108056.7648_70kDaexocystcomponentprotein
197193___________ -1.09 -1.110.0240.0680.0321174210788105526.8093_leflunomideresistance
197366___________ -1.12 -1.120.6850.4920.6711161610406103276.8526_conservedhypotheticalprotein
197617___________ -1.22 -1.150.1190.5720.0641295810637112256.8965_proteinNalpha-acetyltransferasesubunit;transcriptionalsilencing
195045___________ +1.46 +1.210.0030.0030.0271284318703155336.427__
*191536___________ +1.61 +1.400.0010.0020.0041705227392239426.1061_zinc-andcadmiumresistanceprotein
191162___________ +1.05 +1.030.2500.1220.6892118822151217996.1611_aromaticring-cleavingdioxygenase
*191078___________ +2.13 +1.520.0000.0010.0041945041448295306.2149_alanineglyoxylateaminotransferase
*191777___________ +1.71 +1.560.0010.0020.0021769630324276926.2665_ubiquitin-specificprotease
*194722___________ +1.74 +1.670.0000.0010.0022353440976392066.3184_helix-loop-helix(bHLH)transcriptionfactor
19764____________ +1.36 +1.340.0210.0620.0291343618261180116.3664_
191685___________ +1.13 +1.110.2450.1190.6941259014213140056.4154_hypotheticalprotein
195710___________ +1.42 +1.340.0040.0090.0131562622137209976.4636_
196239___________ -1.02 -1.040.2180.4070.1451796017579172666.5117_
*192320___________ +1.51 +1.600.0020.0060.0042470837346396116.5588_proteinserinekinase
194939___________ +1.13 +1.080.0590.0470.1741331615073143656.6051_Monensin/BrefeldinAsensitivity
196624___________ +1.15 +1.180.0070.0210.0151440816580170526.6521_TBCdomainprotein
*195162___________ +1.34 +1.260.0010.0020.0052512433665317296.6974_serine/threonineproteinkinaseoftheMEKKfamily
*194012___________ +1.80 +1.570.0000.0010.0021679430149262856.7425_cyclin,associateswithPho85p
196387___________ -1.18 -1.260.0130.0290.0252542321627202336.7867_
*195322___________ +1.32 +1.260.0010.0020.0043422345167430436.8311_conservedhypotheticalprotein
*197494___________ +1.85 +1.540.0000.0010.0012034837674312656.8746_conservedhypotheticalprotein
195601___________ +1.31 +1.130.0070.0070.0571387818236157306.171__
195241___________ +1.47 +1.300.0020.0040.0151340719673174186.768__
*195569___________ +1.51 +1.280.0040.0050.0391720726010220016.1360_
19855____________ +1.32 +1.220.0020.0040.0111322017434161656.1904_hypotheticalprotein
194363___________ +1.28 +1.170.0060.0060.0581245915925145336.2425_
194492___________ +1.18 +1.070.0250.0230.1021476017396158246.2953_nucleolarprotein|requiredforpre-rRNAprocessingandribosomalsubunitassembly
191171___________ +1.24 +1.170.0070.0080.0411270615805148256.3438_S-adenosylmethionine:diacylglycerol3-amino-3-carboxypropyltransferase|lipidmetabolism
196022___________ +1.37 +1.190.0030.0030.0321357518582161696.3926_hypotheticalprotein
193197___________ +1.26 +1.170.0030.0060.0131688821287196816.4398_
*194791___________ +2.01 +2.080.0000.0000.0002679453915558666.4901_hypotheticalprotein
*191406___________ +1.58 +1.500.0010.0030.0041434222634215466.5359_hypotheticalprotein
196382___________ +1.11 +1.160.2070.5870.1141496616575173116.5835_
195074___________ +1.19 +1.150.0040.0070.0161596618930183886.6301_
*19550____________ -1.16 -1.180.0420.1010.0496796358652577706.6762_pyridoxine(pyridoxiamine)phosphateoxidase
*193314___________ +1.49 +1.500.0000.0020.0012162832149324736.7209_hypotheticalproteininvolvedinvesiculartransport
195281___________ -1.08 -1.050.1990.3260.1495393650118512596.7661_mitoticchromosometransmissioncontrol
197205___________ +1.14 +1.160.0130.0400.0201624818470188356.8105_ureaactivetransportprotein
*197378___________ +1.11 +1.220.0050.0200.0085096256501621606.8538_involvedincellcyclecontrolandionhomeostasis
197631___________ +1.11 +1.110.0270.0520.0451463416281162866.8979_conservedhypotheticalprotein
19634____________ +1.04 -1.020.5050.2790.8151201612540118346.445__
196488___________ +1.14 +1.090.0230.0300.0621181013467128286.1073_
192665___________ +1.19 +1.060.0350.0180.4001262215028133196.1628_supressorofsnf1mutation
191012___________ +1.10 +1.040.1540.0660.8911252213771130086.2168_AP-1clathrinassociatedproteincomplexsubunit
191246___________ +1.16 +1.060.0660.0400.2941227214250129496.2681_
*193215___________ +1.92 +1.850.0000.0010.0012204942378406866.3197_hypotheticalprotein
195221___________ +1.14 +1.040.0560.0230.9641342215242139156.3683_
191381___________ -1.01 -1.070.6330.7160.4253371933374314566.4167_possibleroleintheregulationofactincytoskeletalorganization
193546___________ -1.32 -1.150.0090.0120.0332628819853229506.4655_peroxisomeassemblyprotein(Peroxin-2)
196225___________ +1.18 +1.040.0470.0270.3021309815462136316.5131_cyclinlikeproteininteractingwithPHO85
191938___________ +1.04 +1.000.3490.1950.6191350114089135596.5602_
194170___________ -1.02 -1.030.5760.9640.3371283812596124726.6064_potentialcellwallprotein|memberofagroupofC.albicansorfsthatareweaklysimilartoScCIS3/PIR3/PIR1
196638___________ -1.05 -1.080.3380.2700.3702579624622238746.6535_ser/thrproteinphosphatasePP2C
*196838___________ -3.72 -2.870.0010.0020.0034563912265159056.6987_peroxisomal2,4-dienoyl-CoAreductase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194025___________ -1.11 -1.040.0640.0890.0952793425077268806.7438_endopeptidaserequiredformitosisandsporulation
194584___________ +1.01 -1.020.3110.1480.8591197012052117066.7883_acidphosphatase,secreted
*195337___________ +1.50 +1.380.0000.0010.0021670825137230646.8326_E2ubiquitinconjugatingenzyme
*197506___________ +2.04 +2.270.0000.0020.0011749235697397226.8758_conservedhypotheticalprotein
193337___________ -1.09 -1.070.0630.0920.0891167410738109086.188__hypotheticalprotein
194213___________ +1.60 +1.360.0020.0050.0121431722972195176.789__
*192298___________ -1.04 -1.330.0470.3120.0305871056486440316.1375_
192446___________ +1.23 +1.050.1000.0440.6672470330279259376.1919_highlyconservedhypotheticalprotein
*195227___________ +2.62 +2.870.0000.0000.0001903049832545886.2441_
194410___________ -1.13 -1.130.0270.1670.0221202010618106246.2972_beta-mannosyltransferase
*195209___________ +1.27 +1.180.0080.0110.0381922524469227206.3452_ConservedOligomericGolgicomplex6ComplexedwithCog8p
*195292___________ +3.56 +2.960.0000.0010.0012278781048674486.3942_polarityestablishment/cellularpolarization
*194048___________ -1.11 -1.440.0060.6100.004129599116453898076.4415_
*195732___________ +2.56 +2.840.0000.0010.00035458907001005866.4912_
192143___________ -1.11 -1.120.0140.0400.0231179410593105466.5374_
*193884___________ +2.22 +1.960.0010.0040.0041687237403330256.5854_
194388___________ -1.18 -1.170.0060.0150.01211610980899416.6318_
196668___________ -1.09 -1.100.0400.0600.0701184210860107316.6778_
19338____________ +1.03 +1.160.0760.1860.0671492815441172536.7222_conservedhypotheticalprotein
195268___________ -1.16 -1.120.0150.0290.0321258610864112636.7674_RNApolymeraseIItranscriptionfactor
197217___________ -1.22 -1.130.0060.0150.016118259660105066.8117_ribosomalproteinL4B
197389___________ -1.17 -1.170.1100.5450.0591227310472104996.8550_
197646___________ -1.18 -1.150.0100.0190.0261226010381106626.8995_
*19580____________ +1.29 +1.180.0010.0020.0132351630374277126.465__
191616___________ +1.13 +1.110.0180.0210.0661529917231169806.1089_
*193144___________ +3.43 +3.230.0010.0040.0031542652902498916.1641_MajorRepeatSequence
194734___________ +1.41 +1.330.0010.0030.0031684523681223296.2187_
*192722___________ +1.18 +1.240.0020.0050.0042202625937273626.2697_putativelyinvolvedingrowthregulation
19468____________ +1.07 +1.030.1430.0710.5501289913840132286.3213_hypotheticalprotein
637______________ +1.18 +1.140.0260.0310.0731337115844152906.3700_
195488___________ +1.33 +1.290.0160.0530.0231514720126195796.4182_similartopeptidechainreleasefactor
*192570___________ -2.95 -3.050.0000.0000.00019738666878646526.4671_putativeNADH-ubiquinoneoxidoreductase
193902___________ +1.34 +1.260.0050.0080.0191366418375172166.5146_hypotheticalprotein
*191854___________ +6.44 +4.440.0000.0000.000237458152992210549296.5621_histoneH4
*194184___________ +1.50 +1.460.0010.0020.0022489837293363386.6078_clathrincoatassemblyprotein
*196652___________ +1.47 +1.700.0010.0070.0031648224274280736.6548_
196851___________ +1.19 +1.100.0090.0080.0841434517109158456.7000_chromosomesegregationprotein
*194040___________ +1.43 +1.460.0000.0020.0012777639594406736.7452_
194599___________ +1.03 +1.030.5240.3540.5871214412495125606.7897_
*195352___________ -1.28 -1.360.0020.0040.0116550251007481246.8341_conservedhypotheticalprotein
197520___________ -1.04 -1.140.0710.7510.0352391023071209026.8772_peroxysomal3-ketoacyl-CoAthiolaseA
*195622___________ +4.49 +4.920.0000.0010.0011695576187834746.204__
191173___________ +1.25 +1.200.0080.0110.0291263915754152296.813__ubiquitin-proteinligase(E3)
192429___________ +1.39 +1.250.0020.0030.0231385919299173806.1392_hypotheticalprotein
*19551____________ +1.05 +1.160.0490.2940.0322610827352303916.1932_sharescarboxy-terminaldomainofphosphatidylserinereceptor
*196261___________ +1.41 +1.280.0040.0080.0171538221628196636.2455_
*191111___________ +2.18 +2.390.0000.0010.0003976486553949416.2987_
*191114___________ +1.02 +1.330.0070.1390.0065676458068754466.3466_conservedhypotheticalprotein
193762___________ +1.35 +1.270.0030.0060.0151359218376172206.3957_hypotheticalprotein
*195591___________ -1.58 -1.490.0090.0140.0324122826032276456.4432_
191063___________ +1.21 +1.070.0100.0080.1241434517367153546.4926_conservedhypotheticalprotein
*196170___________ +1.52 +1.380.0010.0020.0092425336914335516.5391_microtubule-associatedproteinrequiredformicrotubulefunctionduringmatingandmitosis|nuclearfusionprotein
193132___________ +1.09 +1.140.1930.2870.1583635839648414376.5869_transmembranecationantiporterinvolvedinzincionhomeostatisandmeioticrecombination
*195118___________ +1.22 +1.450.0070.0260.011918321123891333936.6332_spindle-polebodyprotein
*196683___________ +1.16 +1.270.0220.0710.0273314838356420806.6792_
*19351____________ +1.20 +1.130.0060.0080.0302040524547230896.7235_conservedhypotheticalprotein
195256___________ +1.17 +1.050.0150.0100.1801317915474138666.7686_similartomammalianintegrin
*197232___________ +1.80 +1.790.0010.0030.0022186839451390936.8132_
197403___________ -1.08 +1.090.7310.8280.4945612352099609596.8563_conservedhypotheticalprotein
197663___________ -1.02 +1.100.4250.8320.2323668736021403126.9011_conservedhypotheticalprotein
191119___________ +1.09 +1.080.0500.0310.2591219513328132276.487__
*194776___________ +1.34 +1.360.0020.0040.0051970626444267906.1106_
*193149___________ +1.99 +2.040.0000.0000.0002710953959553606.1659_LongchainbaseStimulatesPhosphorylation
196248___________ +1.10 +1.030.2780.1300.8321270113921130746.2200_hypotheticalprotein
19644____________ +1.05 +1.040.1440.0850.3841181312378122756.2714_
193940___________ +1.05 +1.030.2290.1530.3871447615151149386.3227_
*196478___________ +2.14 +2.100.0000.0020.0011946941647408896.3716_glutathiones-conjugatetransporter
194505___________ -1.00 -1.030.7000.9810.4431382613815134706.4197_alcoholdehydrogenase
192584___________ +1.12 +1.150.0500.0740.0791641618375187996.4685_
19212____________ +1.27 +1.210.0010.0040.0041659821124201326.5161_endosometovacuoletransportfactor
19322____________ +1.14 +1.080.0330.0220.1981307014936140656.5636_hypotheticalprotein
*192172___________ +1.66 +1.810.0000.0020.0002305838171417436.6091_D-arabinosedehydrogenase
*19671____________ +1.97 +2.130.0000.0010.0012638052082561916.6564_conservedhypotheticalprotein
196863___________ +1.13 +1.230.2800.5900.1603436638722423796.7012_V0domainofvacuolarH+ATPase
192090___________ +1.09 +1.170.1300.7630.0645648761405658726.7465_partofsmall(ribosomal)subunit(SSU)processosome(containsU3snoRNA)
194612___________ +1.16 +1.050.0270.0140.3481432716673150676.7911_endo-1,3;1,4-beta-D-glucanase
195368___________ +1.01 +1.030.7360.4910.8161274212822130756.8357_conservedhypotheticalprotein
*197538___________ +1.38 +1.490.0030.0090.0071835825409273826.8790_DNArepairandrecombinationprotein
*192781___________ +1.83 +1.580.0020.0040.0152090238184330156.15___
*19454____________ +2.06 +1.940.0000.0010.0012305447497448396.508__
19232____________ +1.12 +1.080.0130.0150.0521195513333129456.1124_
*192823___________ +2.51 +2.870.0010.0030.0021821445714522276.1680_
*196472___________ -2.62 -3.220.0000.0000.00023627090257734586.2215_
*193418___________ +1.72 +1.610.0020.0040.0071452525044234256.2731_
*195569___________ +2.01 +2.350.0010.0040.0031513430378355276.3241_
*193087___________ -1.30 -1.740.0000.0040.0001851131428351065036.3734_smallsubunitribosomalprotein
*193753___________ +1.31 +1.130.0090.0100.0504738262296536656.4213_zincfingertranscriptionfactor
192742___________ -1.01 -1.060.5730.7430.3612428424070229576.4698_
*192417___________ +1.45 +1.400.0000.0020.0022388634706335166.5176_structuralmaintenanceofchromosomesprotein
*193974___________ -3.34 -3.780.0000.0020.0015858817532154926.5650_1-pyrroline-5-carboxylatedehydrogenase
193415___________ +1.00 -1.060.8530.6040.9537008670359664066.6110_
*192770___________ +2.35 +2.270.0000.0000.0003492681926794396.6582_hypotheticalprotein
*191896___________ -3.69 -4.810.0000.0010.0008441622880175506.7026_
*192075___________ +2.60 +2.360.0000.0000.000456461185571075016.7480_filamentousgrowth,cellpolarityandelongation
*194626___________ +1.15 +1.020.0250.0110.7201531317664156226.7925_TORsignaltransductionpathway|associateswithPp2apandSit4pproteinphosphatasecatalyticsubunits
197290___________ -1.02 -1.090.5180.5930.3558540783720782196.8371_Sm-likeprotein;partofcomplexinvolvedinmRNAdecay
196827___________ +1.16 +1.210.1610.4070.1011462116890177486.8804_pre-mRNAsplicingfactoraffecting3splicesitechoice
Cachs2___________ +1.01 +1.020.5610.3120.918122801240312554Cachs2_
*191010___________ +1.49 +1.370.0010.0040.0031598023776218326.220__
*191936___________ +1.45 +1.360.0020.0040.007796581152811083486.832__

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*191975___________ -1.20 -1.250.0030.0130.0054687839210375766.1409_componentofU4/U6.U5pre-mRNAsplicingcomplex
193518___________ +1.02 +1.120.3930.6680.229984811001871103306.1951_mitochondrial2-oxodicarboxylatetransportprotein
192160___________ -1.02 -1.000.9560.7920.9413032829771302876.2474_
*191095___________ +1.98 +1.680.0000.0000.0012586751128434116.3002_nuclearporeprotein
*194274___________ +1.83 +1.650.0010.0020.0031335024479219656.3483_
*194245___________ +1.49 +1.400.0010.0030.0032318634474324216.3979_conservedhypotheticalprotein
*19310____________ +1.43 +1.490.0010.0040.0042084229773310146.4448_
*192850___________ +2.01 +1.790.0020.0050.0064403888482788756.4944_
*196185___________ +1.67 +1.840.0000.0010.0002755145962507896.5406_hypotheticalprotein
*192261___________ +1.58 +1.570.0000.0010.0014029963873631836.5885_spliceosome-associatedessentialprotein
*195102___________ +2.14 +2.460.0070.0140.0201779838089437776.6348_
196699___________ -1.06 -1.080.1190.1490.1434489642158414746.6808_histidinolphosphatase
194439___________ +1.07 +1.130.0240.0810.0281621317288182716.7252_hypotheticalmembraneprotein
195243___________ -1.02 +1.020.5380.7070.3383854637639392726.7699_anthranilatesynthase/indoleglycerolphosphatesynthase,tryptophanbiosynthesis
*197247___________ +1.69 +1.480.0000.0010.0023136352946465426.8148_
197417___________ -1.05 -1.120.0550.1420.0531283325122490511408776.8578_
*197678___________ -4.36 -4.940.0000.0000.0007359851687201490106.9025_
195126___________ -1.10 +1.010.0650.0300.5503629233046368226.38___
6527_____________ +1.29 +1.170.0040.0070.0201269616320148436.527__
*191369___________ +1.60 +1.330.0010.0010.0051875029952249156.1149_
*194330___________ +1.35 +1.280.0040.0070.0131585821408202926.1694_
*191800___________ +1.99 +2.090.0000.0000.0003741874610782256.2232_involvedinvacuolartargeting
193637___________ +1.13 +1.120.0460.0450.1201236013999138876.2752_hypotheticalprotein
*194328___________ +1.87 +1.920.0000.0000.0004008175118768596.3258_copper-transportingATPase
19844____________ +1.36 +1.260.0020.0040.0111485420129186586.3749_
194895___________ -1.29 -1.280.0050.0150.0122526419588197156.4231_hypotheticalprotein
*194660___________ -1.52 -1.600.0010.0030.0043956332601772479426.4711_ribosomalproteinS6A(S10A)(rp9)(YS4)
*194294___________ -1.72 -1.720.0000.0000.0004520026255262156.5192_involvedinimportofcytochromec
*196151___________ +1.17 +1.380.0030.0590.0033690443332508066.5663_Arpcomplexsubunit
192899___________ +1.23 +1.140.0060.0090.0261588019573181496.6123_peroxisomal2,4-dienoyl-CoAreductase
*194250___________ -1.92 -2.260.0000.0020.0014634624128205216.6595_
191880___________ +1.02 +1.020.7840.7980.5642178422315222336.7041_
*192063___________ +1.18 +1.310.0010.0160.0023350739569440436.7492_conservedhypotheticalprotein
197013___________ +1.01 +1.000.9200.9890.7191651316703165646.7939_hypotheticalprotein
197303___________ +1.14 +1.230.0040.0120.0111891221565232916.8384_hypotheticalprotein
196811___________ -1.00 -1.020.8050.5750.8181358413556132746.8820_mitochondrialproteinrequiredforironmetabolism
Cafks3___________ +1.04 +1.070.4870.2830.705123241286413134Cafks3_
*192970___________ +1.80 +1.930.0010.0040.0031659629793320646.240__
191212___________ +1.31 +1.250.0030.0050.0221394518211174986.844__
19458____________ -1.00 +1.040.4820.8430.2712070620695214516.1428_
196027___________ +1.40 +1.230.0010.0020.0141441820142177156.1968_
*194069___________ +1.42 +1.390.0010.0030.0061475520884204876.2487_hypotheticalprotein
194060___________ +1.04 +1.150.2040.5250.1172786829115320026.3017_3-deoxy-D-arabino-heptulosonate7-phosphate(DAHP)synthaseisoenzyme|3-deoxy-D-arabino-heptulosonate7-phosphate(DAHP)synthaseisoenzyme|2-dehydro-3-deoxyphosphoheptonatealdolase,tyrosine-inhibited
*195184___________ +1.91 +2.280.0000.0010.0002609849903595436.3496_GEFinpheromoneresponsepathway
*192930___________ +1.35 +1.540.0020.0060.0061499620235231026.3995_
195522___________ -1.11 +1.010.9720.8660.8963878734813390936.4464_hypotheticalprotein
*192475___________ +1.24 +1.340.0060.0330.0093089638452414766.4960_hypotheticalprotein
*196202___________ +2.31 +2.570.0000.0010.0011957045234503636.5423_
*192246___________ +2.40 +2.840.0000.0000.0001817743610515526.5900_conservedhypotheticalprotein
*191998___________ +1.36 +1.300.0010.0030.0041984827068258976.6362_hypotheticalproteinsimilartoBotulinumneurotoxintypeB
*194114___________ -2.40 -2.170.0000.0000.0005545123144255976.6822_long-chain-fatty-acidCoAligase|Lipidandfatty-acidmetabolism
*194451___________ +1.50 +1.720.0020.0060.0071533423061264326.7265_
196967___________ -1.09 +1.010.1670.0850.5483458131589347706.7713_mammalianintegrinanalogue
*197261___________ -1.64 -1.450.0010.0030.0047273944413500196.8162_
*197433___________ +2.19 +3.130.0000.0010.0013000365799938036.8592_
*195999___________ +1.91 +2.090.0020.0050.0061549629661323416.9040_
*1955_____________ +1.57 +1.470.0010.0020.0023032147455445276.56___
*193870___________ -1.49 -1.700.0000.0010.0008105754254476076.551__
193170___________ +1.01 -1.090.5780.6950.3773287633342302276.1165_
192547___________ +1.20 +1.150.0160.0170.0671259015168144696.1713_
192280___________ +1.31 +1.170.0590.0390.2391659621805193356.2247_
194222___________ +1.35 +1.310.0050.0100.0181339618109176156.2767_desensitizationtoalphafactorpheromone|GTPaseactivatingprotein
*192853___________ +1.78 +1.580.0000.0010.0022356841953373386.3277_hypotheticalprotein
193461___________ +1.14 +1.060.0430.0250.2771549417630164936.3764_
*191280___________ +5.78 +6.360.0000.0000.000455422631782895226.4245_translationinitiationfactoreIF3subunit
19579____________ +1.02 +1.040.8930.9700.6763520836048365486.4729_
*194281___________ +1.94 +1.710.0000.0000.001988821915901686846.5205_interactswithforkheadprotein
*196136___________ -2.76 -3.260.0000.0000.0006233222563191316.5678_mitochondrialribosomeproteinL4
195842___________ +1.02 +1.010.5780.4330.5521555315884156656.6136_sirohemesynthase/methioninemetabolism
*194236___________ +1.50 +1.610.0010.0030.0031613524252259096.6608_
191867___________ +1.14 +1.130.0130.0170.0481731219814195166.7053_permeaseofmajorfacilitatorsuperfamily
*193812___________ +1.24 +1.100.0130.0150.0562273928132251036.7507_regulatorproteininvolvedinpleiotropicdrugresistancethatformsaribosome-associatedcomplex|DnaJ/HSP70chaperone
*197025___________ +2.28 +1.980.0000.0000.00146770106430925026.7952_
*197316___________ +1.37 +1.350.0300.2140.0222837538889382606.8396_
*196798___________ +2.71 +2.310.0010.0020.0022670372442615676.8832_
Cassa2___________ -1.04 -1.050.3960.2090.752121631173711589Cassa2_
*191544___________ +1.59 +1.530.0010.0040.0031491323735227896.255__
192124___________ -1.02 +1.030.4940.7580.2913433533662353426.863__putativedehydrogenase
*19117____________ +1.72 +1.630.0000.0020.0021791230821291486.1445_
*19691____________ +4.52 +7.140.0000.0010.00016634752261188356.1984_glycerol-3-phosphatedehydrogenase
*19100____________ +1.42 +1.320.0020.0030.0131503921391198046.2503_triacylglycerollipase
193646___________ +1.34 +1.160.2240.1160.5831252351679691449136.3031_coppertransportprotein
*193962___________ +3.02 +3.110.0000.0010.0001704551465529856.3509_
*19699____________ +3.13 +3.420.0000.0000.0001851457874632586.4009_hypotheticalprotein
193182___________ +1.00 +1.000.8700.9350.6451743017442174886.4478_
*192462___________ +1.88 +1.810.0000.0010.0011875935180338926.4973_RNApolIItranscriptioncofactor
*196285___________ +2.70 +2.650.0000.0000.0002936379271778666.5435_proteinphosphatasetypeI
*194933___________ +2.38 +2.430.0000.0020.0011938946199471716.5913_oleatedelta-12desaturase
*191414___________ +1.22 +1.130.0080.0080.0521170881424611324616.6383_hypotheticalprotein
*194097___________ -1.27 -1.150.0050.0070.0233510627535306596.6839_hypotheticalprotein
19899____________ -1.21 -1.200.0050.0100.0172468020474206336.7278_mannose-P-dolicholutilizationdefect1protein|transmembraneprotein
*196980___________ +1.19 +1.130.0050.0080.0262723532319307156.7726_proteinkinasesimilartonitrogenpermeasereactivator
197275___________ +1.20 +1.180.0040.0090.0141505418031176986.8175_reversetranscriptase
197446___________ -1.13 -1.240.0540.1140.0613473830825279576.8606_methylene-fatty-acyl-phospholipidsynthase
195984___________ +1.01 -1.010.2550.8600.1261806018186178946.9054_
194652___________ +1.09 +1.150.0100.0220.0231238313483141826.77___
199132___________ +1.01 -1.000.7950.9490.5442248422641224286.570__ubiquinol-cytochromecoxidoreductasesubunit6
*19117____________ +1.60 +1.320.0020.0030.0091595525559210936.1184_
*19709____________ +1.16 +1.110.0070.0080.0402171625192240866.1729_20Sproteasomesubunit
*193758___________ +1.33 +1.160.0010.0020.0152309830757267846.2264_putativemembraneprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*193451___________ +2.12 +2.440.0010.0040.0041534432501374566.2788_
*193618___________ +4.19 +4.540.0000.0000.000304821277931382856.3290_
*194358___________ -1.50 -1.580.0020.0050.0063360722368212586.3780_
192212___________ +1.08 +1.010.2610.1350.6241795219454180656.4257_hypotheticalprotein
*192114___________ +17.29 +14.890.0000.0000.00084804146611412628606.4747_peroxisomalurateoxidase|uricase
194814___________ +1.04 +1.070.0690.0580.1741228912779131336.5220_hypotheticalprotein
*19585____________ -1.74 -1.910.0010.0040.0053358619285175466.5695_mitochondrialribosomalproteinofthelargesubunit
195830___________ +1.05 +1.110.0450.0510.0981833219222202916.6148_translocationofproteinprecursorsacrossER|Hsp70familychaperone
*195791___________ -2.63 -2.710.0000.0010.00118381669898679506.6624_
*19500____________ +1.13 +1.210.0120.0600.0152572028999312466.7071_translationinitiationfactor3(eIF-3)zetasubunit
*193827___________ -1.24 -1.350.0030.0100.0082991624033222316.7522_conservedhypotheticalprotein
*197038___________ +1.49 +1.690.0010.0040.0012745840924463476.7965_
197328___________ -1.02 -1.070.3670.6260.2161924518817180336.8409_Candidaalbicansp100homolog
*196786___________ +1.45 +1.470.0010.0030.0031581622961233246.8845_hypotheticalprotein
42026____________ -1.01 -1.050.9810.9130.8931178911697112794.2026_
*19225____________ +1.20 +1.220.0020.0040.0072540630543309326.275__hydroxyisocaproatedehydrogenase
*192743___________ +1.40 +1.250.0010.0020.0071680623602210346.886__
191492___________ +1.22 +1.120.0040.0050.0301302915897146276.1461_pre-mRNAsplicingfactor|U1snRNPprotein
191675___________ +1.20 +1.210.0030.0070.0081883822599228796.1997_conservedhypotheticalprotein
*192727___________ +1.55 +1.550.0010.0020.0121524223589236666.2519_glutaredoxin
194523___________ +1.11 +1.060.0710.0670.1521478116475157106.3048_5,10-methenyltetrahydrofolatesynthetase|folinicacidutilization
19639____________ +1.23 +1.190.0040.0070.0161511218545180146.3526_regulatesprocessingof27Spre-rRNA
194752___________ +1.29 +1.130.1600.1770.184889551150951005366.4022_zincfingertranscriptionfactor
*192832___________ -1.17 -1.070.0450.0360.1595167144094481556.4493_conservedhypotheticalprotein
*193474___________ +1.61 +1.540.0010.0020.0031672726909257866.4985_ser/thrproteinkinaseinvolvedinchromosomesegregation
194685___________ +1.07 +1.040.1170.0660.3971242813309128806.5451_hypotheticalprotein
*19198____________ -1.35 -1.400.0010.0040.0043393525153242906.5929_
*191428___________ +1.55 +1.390.0010.0020.0041619425072224356.6397_hypotheticalprotein
194085___________ -1.02 +1.120.3720.8280.1974979248759556876.6851_hypotheticalprotein
*19882____________ -1.63 -1.750.0000.0020.00110672665336608476.7293_
*196992___________ +1.70 +1.900.0010.0040.0041562726581296846.7738_multidrugresistancetransporter|similaritytoantibioticresistanceproteins
19940____________ +1.16 +1.090.0130.0100.1261581318342172146.8189_GTPase-activatingprotein
197458___________ -1.05 +1.040.1980.2110.2122154020539223926.8618_coiledcoilprotein
*195970___________ +1.19 +1.300.0020.0070.0061778021142230816.9067_ATP-dependentDNAhelicaseinvolvedinDNArepair
19923____________ +1.31 +1.220.0020.0040.0091296316957158116.99___
*192030___________ +1.51 +1.260.0010.0010.0103623854726457286.594__
*191526___________ +1.47 +1.490.0030.0080.0111317119322195986.1206_
*191180___________ -1.22 -1.320.0000.0040.0013240026587244686.1746_
*19470____________ +1.68 +1.690.0020.0080.0062462841394415456.2281_
191491___________ +1.05 +1.070.0640.1120.0771300013694139236.2805_
193658___________ +1.20 +1.170.0060.0090.0251321415852155196.3303_conservedhypotheticalprotein
195720___________ +1.09 +1.040.0700.0490.2241660618065173016.3799_monocarboxylatetransporterproteins
*192613___________ -2.22 -2.420.0000.0000.0003143031417571299086.4272_involvedincellwallbiogenesisandarchitecture
*192099___________ +1.40 +1.470.0050.0120.0141406219750206496.4761_
194142___________ +1.11 +1.040.1070.0540.4821771419610184456.5239_
*192980___________ +1.25 +1.370.0020.0070.0041786622354243916.5708_
192481___________ +1.08 +1.080.0580.0730.1001208613098130016.6162_hypotheticalprotein
*195805___________ -3.17 -3.830.0000.0000.00016728452833436856.6639_mitochondrialD-lactateferricytochromecoxidoreductase
*19486____________ +1.24 +1.140.0130.0120.0761699020992193586.7085_largesubunitofdynactincomplex
193843___________ -1.12 -1.230.0950.8240.0452424221639197286.7538_signalrecognitionparticlereceptor|ERprotein-translocationcomplexsubunit
195030___________ +1.37 +1.060.1480.0980.3284506461714477366.7979_proteininvolvedingenomestability
197342___________ +1.34 +1.380.0510.1690.0441426419158197336.8423_conservedhypotheticalprotein
*196773___________ +1.71 +1.850.0020.0060.0081492625554276846.8857_
42436____________ -1.04 -1.020.5490.3540.6491194111452116624.2436_
*193854___________ +1.73 +1.570.0010.0030.0021576027278246836.290__
191290___________ +1.34 +1.270.0010.0030.0071330317821168616.909__xylulokinase
*196465___________ +1.96 +1.860.0010.0020.0041543030210286776.1477_
19264____________ +1.23 +1.260.0030.0050.0111273815644160136.2012_
*192747___________ +1.62 +1.290.0010.0020.0091679927221216956.2537_regulatorofglucose-inducedgenes
194801___________ +1.15 +1.160.0090.0160.0251301015010150446.3060_tRNAisopentenyltransferase
191495___________ +1.23 +1.210.0040.0080.0141323316313160286.3546_
195820___________ +1.28 +1.250.0100.0130.0371271116331158876.4040_
*195639___________ -1.26 -1.260.0160.0430.02510260981212816566.4507_
*194511___________ +1.44 +1.300.0010.0020.0052466835632319556.5000_leucinerichrepeatgenefamilyprotein
*193735___________ +1.23 +1.090.0070.0060.0774053050054443026.5465_
195148___________ +1.43 +1.310.0030.0060.0181281818305168086.5944_
*191552___________ -9.47 -10.030.0000.0000.00092382797589921486.6410_cyclophilin(peptidylprolylisomerase)
*196716___________ +1.16 +1.340.0030.0220.0043394139329454796.6865_mRNAcapmethyltransferase
*19871____________ +1.33 +1.380.0040.0100.0131477619676203416.7307_
193014___________ +1.15 +1.030.1150.0490.7975007055781885142596.7751_14-3-3protein
19954____________ +1.13 +1.160.0160.0490.0231509917047175206.8203_DnaJsubfamilyAmember
*195397___________ -1.13 -1.270.0010.0140.0023648432193287616.8633_conservedhypotheticalprotein
*195958___________ +1.31 +1.290.0010.0020.0032100227471270806.9079_multidrugresistance|ABCtransporter
*196889___________ +1.21 +1.170.0020.0030.0192959635929345886.121__
191008___________ +1.30 +1.130.0070.0070.0611313617013148386.612__hypotheticalprotein
191089___________ +1.36 +1.190.0050.0080.0211349618357160296.1222_
194689___________ +1.17 +1.090.0100.0100.0751275314970139416.1769_
193352___________ +1.17 +1.070.0160.0110.1621258014756134916.2296_putativedehydrogenase
194427___________ +1.09 +1.100.0280.0310.0791232213471135606.2827_involvedinkinetochorefunctionandubiquitin-mediatedproteolysis|kinetochoreproteincomplexCBF3
195040___________ +1.27 +1.220.0080.0120.0341317016757160146.3317_componentofthekaryopherindockingcomplexofthenuclearporecomplex
192564___________ +1.32 +1.260.0030.0070.0101342117776169146.3813_conservedhypotheticalprotein
*193540___________ -1.27 -1.200.0050.0070.0296742452967559846.4286_ATP-dependentRNAhelicase
*195619___________ +1.47 +1.350.0010.0020.0061511422184204266.4778_hypotheticalprotein
193865___________ +1.05 +1.110.0270.0560.0431458115319161286.5256_
191255___________ +1.11 +1.090.0570.0430.1871312414608143286.5722_
192496___________ +1.05 +1.030.5040.3260.6041440915092147726.6177_transporterinvolvedinnitrogenutilization
192962___________ +1.08 +1.030.1360.0910.3111696818296174456.6654_hypotheticalprotein
*191471___________ -3.44 -3.960.0000.0000.00019203055840485126.7102_cytochromecoxidasesubunitIV
*196568___________ +1.87 +2.020.0010.0050.0041558429104314046.7555_
195016___________ +1.03 +1.030.4640.2540.7781302413421133656.7993_conservedhypotheticalprotein
*197116___________ -1.17 -1.210.0320.1560.0284699840019388036.8437_memberoftheRNApolymeraseII-associatedPaf1complex
*196759___________ +2.53 +3.060.0000.0010.0011846946732564426.8872_negativeregulatorofearlymeioticexpression
42696____________ +1.06 +1.070.6500.3860.9111406514845151084.2696_
192252___________ +1.24 +1.160.0050.0060.0311248615532144716.306__
191531___________ +1.32 +1.120.0040.0050.0341264816751141706.931__mRNA3'-endprocessingprotein
*192802___________ +1.20 +1.170.0060.0080.0292390028720280656.1495_
194466___________ +1.27 +1.180.0020.0040.0101304616527154026.2033_
*19801____________ +1.50 +1.450.0030.0060.0121989429778287966.2551_
194557___________ +1.14 +1.100.0260.0240.1091288414673141926.3076_spindlepolebodyprotein
192459___________ +1.37 +1.300.0010.0030.0051548021180200936.3561_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
193923___________ +1.11 +1.150.0170.0240.0481444116095165706.4053_conservedhypotheticalprotein
*196213___________ +1.18 +1.200.0020.0050.0053032235656364216.4524_
65014____________ +1.12 +1.080.0210.0180.1121264014198136926.5014_
192691___________ +1.16 +1.240.0040.0090.0111381616047171196.5480_
195138___________ -1.01 +1.010.8850.8730.6831590515724160486.5960_hypotheticalprotein
*191566___________ +1.19 +1.260.0040.0440.0052228626600280446.6423_U3snoRNPprotein|strongsimilaritytoS.pombebeta-transducin
196730___________ +1.05 +1.120.1550.3670.1032616727385293716.6877_
*196934___________ -2.01 -1.810.0000.0010.0013838619105211696.7320_proteintransport;pentamidineresistance
193029___________ +1.02 -1.040.6280.8740.3871523815507147026.7766_enpyl-CoAhydratase,mitochondrial
19968____________ +1.05 -1.010.2550.1150.9711272713344125606.8217_conservedhypotheticalprotein
*195411___________ +1.13 +1.180.0110.0560.0133198636045378246.8647_E2ubiquitin-conjugatingenzyme
195942___________ +1.02 -1.010.7030.4310.9701511515467149846.9095_inhibitorofTranslationTermination
*193661___________ -1.03 -1.390.0040.6770.0035718855417410906.135__
191022___________ +1.16 +1.110.0160.0260.0381338115543148856.643__leucinerichrepeat
19920____________ +1.16 +1.090.0120.0090.1221217114085133106.1242_
193291___________ -1.03 -1.080.5090.5720.3553432733186316956.1781_hnRNPmethyltransferase
*191960___________ +2.22 +2.150.0010.0020.0021811240252388976.2316_
194963___________ +1.09 +1.090.0280.0220.1331244213515135686.2842_proteinphosphataseTwoC-Interactingprotein
*194887___________ +3.79 +3.280.0000.0000.0001980475084648906.3331_calcofluorresistance|involvedincellwallbiogenesisandarchitecture
195289___________ +1.06 +1.060.0890.0960.1421203412765128016.3828_putativesteroidsulfotransferase
*19291____________ +1.83 +1.750.0000.0010.0012822451716493706.4302_involvedinproteinsumoylation
192684___________ +1.10 +1.060.0420.0290.1981272914051134706.4793_
*196544___________ +1.23 +1.170.0070.0070.0571440217707167926.5268_
65735____________ +1.02 +1.030.6710.4970.6351400114226143616.5735_
195763___________ -1.11 -1.140.0070.0330.0101998317927175886.6195_gluconatedehydrogenase
192949___________ +1.05 +1.030.1320.1070.2371391014635142616.6666_
*191458___________ +1.25 +1.300.0020.0050.0051884223579245366.7115_tRNA-specificadenosinedeaminasesubunit
*196582___________ +1.80 +1.630.0000.0000.0013747467574612676.7570_20SproteasomesubunitC1
*195003___________ +1.38 +1.370.0090.0140.0301260017404172046.8006_conservedhypotheticalprotein
*197104___________ +2.18 +2.040.0000.0000.0012634457489537916.8449_putativeGPI-anchoredmembraneprotein
196747___________ +1.57 +1.550.3390.7590.1822877245121446596.8884_conservedhypotheticalprotein
42811____________ +1.08 +1.080.0710.0520.2101211813073130464.2811_
*19364____________ +1.53 +1.360.0000.0010.0033307250466448796.323__
*19185____________ -1.39 -1.400.0030.0090.0093466624916246806.947__
*192657___________ +1.62 +1.290.0020.0030.0131486324049192116.1511_hypotheticalprotein
193589___________ +1.34 +1.170.0020.0030.0181339217951157256.2047_requiredforchromosomepairing
19107____________ +1.32 +1.280.0030.0070.0101328417542170506.2568_
19450____________ +1.16 +1.050.0410.0300.1761205913998126996.3089_putativetransmembraneprotein
*192208___________ +1.52 +1.280.0010.0030.0071958829852251226.3577_
194669___________ -1.07 -1.130.3090.3670.2422187920427193666.4067_aspartateaminotransferase
194374___________ +1.29 +1.220.0020.0050.0041665021456203486.4539_U1snRNA-associatedprotein;pre-mRNAsplicing
193327___________ +1.33 +1.260.0030.0060.0101277116996160496.5028_
*196304___________ +1.33 +1.360.0010.0030.0021721822847234816.5497_L-aminoadipate-semialdehydedehydrogenase
192035___________ +1.09 +1.050.0850.0470.3721483116191155366.5974_hypotheticalprotein
*191635___________ -2.30 -2.280.0000.0000.0008106003517623549756.6437_largesubunitribosomalproteinL12.e
*195654___________ -1.34 -1.260.0030.0050.01310196276037806856.6894_zincmetalloprotease|a-factorprecursorprocessing
196949___________ +1.18 +1.090.0140.0100.1301270614940138056.7335_hypotheticalprotein
*193043___________ -1.43 -1.500.0000.0000.0003972827778264426.7780_triglyceridelipase
*193231___________ +1.19 +1.170.0110.0130.0511398016665163786.8231_cellcycleprotein
*195424___________ +1.99 +2.260.0010.0030.0011578731393356976.8660_hypotheticalprotein
*195928___________ -2.46 -2.730.0000.0000.0006248322540172287426.9109_acidicribosomalproteinP2B|ribosomalproteinP2B(YP2beta)(L45)
*193100___________ +2.34 +2.180.0000.0010.0011813742432395036.149__
194404___________ +1.38 +1.260.0040.0070.0171467620187184386.657__
*191860___________ +1.08 +1.210.0280.0810.0343963442921478206.1260_
192168___________ -1.01 -1.010.6020.6190.4312688726507266146.1805_hypotheticalmembraneprotein
191647___________ +1.19 +1.110.0360.0320.1201842421962204346.2333_hypotheticalprotein
19928____________ +1.23 +1.150.0240.0450.0441475518098169136.2860_hypotheticalprotein
194649___________ +1.25 +1.210.0020.0040.0131865623391225376.3345_
*19832____________ +1.46 +1.350.0000.0020.0021726225215232186.3844_
*194473___________ +1.83 +1.830.0000.0020.0011636629880299466.4314_spindlepolecomponent
19284____________ -1.13 -1.020.1620.0810.5474029835609395496.4813_hypotheticalprotein
*193008___________ -1.89 -1.900.0000.0000.0009060448028477426.5281_biosynthesisofcoenzymeQ
193582___________ +1.13 +1.060.0300.0240.1441684019094178236.5747_conservedhypotheticalprotein
*196598___________ +1.19 +1.470.0040.0680.0035263062474771966.6211_
*194533___________ -1.27 -1.050.0080.0060.1363267225687311626.6679_ligatin|traffickingreceptorforphosphoglycoproteins
*191444___________ +1.15 +1.170.0140.0380.0243637241750424696.7129_epsinN-terminalhomology-containingprotein|clathrinbindingprotein,requiredforendocytosis
*196038___________ +1.25 +1.360.0030.0060.0131687821136230076.7582_putativetranscriptionalregulator
194988___________ +1.04 +1.070.0960.1640.0981293613490138286.8020_
*197091___________ -2.77 -2.550.0000.0000.0006367323009249476.8462_conservedhypotheticalprotein
*197550___________ +1.04 +1.130.0440.3950.0262145622399242186.8898_ORFMSV011leucinerichrepeatgenefamilyprotein
42889____________ +1.04 +1.080.1020.1360.1241234412790133104.2889_
19384____________ +1.05 +1.060.1270.0960.2571675617604177866.341__
194231___________ +1.26 +1.120.0040.0040.0401306216514146246.966__
*192818___________ +1.38 +1.290.0030.0070.0111561221616201796.1525_
*19377____________ -1.87 -1.540.0010.0020.0122005621071221298586.2069_glycophospholipid
*194869___________ +1.25 +1.200.0020.0060.0041953124390234136.2584_GATAtypetranscriptionalactivatorofnitrogen-regulatedgenes
191308___________ +1.22 +1.200.0060.0110.0191480618025178266.3105_
192607___________ -1.01 +1.040.7960.6240.7102830028075293596.3592_
191958___________ +1.09 +1.040.0470.0250.3891254113669130276.4081_hypotheticalprotein
*1952_____________ +1.19 +1.290.0030.0230.0043299439184424856.4554_mitochondrialproteinwithroleinironaccumulation
191964___________ +1.11 +1.090.0260.0260.0931293114332140716.5040_conservedhypotheticalprotein
196318___________ -1.32 -1.020.2870.1360.8098206862273802006.5511_conservedhypotheticalprotein
*192047___________ +1.74 +1.830.0000.0000.0002824149069516186.5986_conservedhypotheticalprotein
191619___________ +1.21 +1.150.0050.0070.0321629619665187846.6453_kinaseofRNApolymeraseIIcarboxy-terminaldomain(CTD),alphasubunit
*195666___________ +1.63 +1.730.0000.0020.0013302753882570776.6906_transcriptionalcoactivator
*194857___________ -1.47 -1.250.0000.0010.0074783232507382266.7354_hypotheticalprotein
193055___________ -1.14 +1.010.0130.0070.5282772624258279296.7792_subunitofRNApolymeraseIIholoenzyme
*193244___________ -1.95 -1.780.0000.0000.0013615818532202586.8244_conservedhypotheticalprotein
*195438___________ +1.33 +1.530.0000.0040.0011951025905298076.8674_hypotheticalprotein
*195912___________ +1.48 +1.850.0010.0040.0022010729728371626.9123_
*195057___________ +1.25 +1.190.0040.0060.0171788622355212346.16___
192723___________ +1.07 +1.100.1430.2700.1131307613939143586.678__
*191926___________ +1.46 +1.620.0030.0090.0071378020148222696.1277_putativetranscriptionfactor
61822____________ +1.15 +1.090.0300.0250.1321304614954141856.1822_
192539___________ +1.09 +1.020.2860.1700.5012072122661210666.2348_hypotheticalprotein
193699___________ +1.02 +1.020.2920.1440.7401253812850127986.2878_proteintyrosinephosphatase
196499___________ +1.17 +1.140.0130.0220.0331314115370149666.3364_DNA-directedRNApolymerase
192391___________ +1.23 +1.320.0030.0100.0061556219211204886.3857_conservedhypotheticalprotein
*193401___________ +1.16 +1.060.0280.0240.1193070835471326206.4330_involvedinvacuolarproteinsorting
19604____________ +1.16 +1.350.0110.0320.0201323415325178616.4827_phenol2-monooxygenase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
191362___________ +1.11 +1.080.1140.0550.5441360715091146966.5294_suppressorofmitochondrialmutationintRNA(asp)gene
193567___________ +1.04 +1.020.2830.1360.7631295413452131546.5763_
*196612___________ +1.32 +1.260.0090.0110.0392934038659370556.6224_electron-transferringflavoprotein,betachain
194545___________ +1.16 +1.080.0320.0250.1531367315904147976.6691_transcriptionfactorsimilartoSWI4
196879___________ +1.21 +1.110.0910.0430.5421692920466188296.7143_tRNAsplicingendonucleasesubunit
*196052___________ +1.01 -1.190.0340.6370.0186872869285577146.7596_putativeproteinphosphataseandproteinfoldingchaperone
*197136___________ +1.64 +1.660.0030.0060.0101603226296265966.8038_
197077___________ +1.09 +1.030.2980.1780.5071803519637185516.8476_transmembranesubunitofferricreductase
*197564___________ +1.25 +1.370.0030.0110.0061472118378201546.8912_DNA-directedDNApolymeraseepsilon,subunitB
43072____________ +1.14 +1.210.0170.0320.0341390815814167734.3072_
*194257___________ +3.69 +3.870.0000.0020.0011538456803595126.359__
196245___________ -1.02 -1.030.3160.4150.2292072220369201276.985__
*19852____________ +1.49 +1.480.0000.0010.0012510837335372206.1542_Gpi-anchoredasparticprotease
*194736___________ +2.92 +2.520.0000.0010.0011878854849474246.2087_vacuolaralcalinephosphatase
19130____________ +1.45 +1.550.0030.0060.0111386720146214256.2602_vacuolarproteinsortingproteinkinase
191706___________ +1.13 +1.100.0260.0220.1161267214366139276.3121_TFIIHregulator
192789___________ +1.29 +1.240.0060.0060.0391839623788228916.3606_
191753___________ +1.15 +1.130.0230.0290.0651257414482142476.4096_
*195689___________ -1.13 -1.270.0060.1240.0051289541137601019026.4567_sec28pepsilon-COPcoatomersubunit
195862___________ +1.33 +1.280.0040.0080.0131464319454187306.5054_arginase
196336___________ -1.05 -1.050.5390.7210.3364404241961420936.5528_
*196457___________ +1.35 +1.470.0040.0150.0081492020148219106.6002_conservedhypotheticalprotein
*193439___________ +1.92 +1.730.0000.0010.0032676051390462476.6466_hypotheticalprotein
193125___________ +1.08 +1.110.0610.1040.0772116122794233886.6920_conservedhypotheticalprotein
194842___________ +1.05 +1.010.3090.1620.6504449746710450946.7369_hypotheticalprotein
*196450___________ +1.66 +1.660.0010.0030.0031726028643287356.7804_hypotheticalprotein
*193256___________ +1.49 +1.350.0020.0040.0091724425634232766.8258_
*195450___________ -2.10 -2.630.0000.0010.000232286110546882066.8686_2-enoylthioesterreductase
195901___________ +1.28 +1.200.0080.0100.0381547019758186196.9137_
*194956___________ +2.39 +2.130.0020.0040.0061483135512315886.52___
*19767____________ +1.76 +1.860.0000.0000.0002772948928516816.696__
191989___________ -1.03 -1.070.2890.5550.1723845437238360046.1293_DefectiveCellWall
*194634___________ +1.22 +1.220.0050.0140.0132546230988309616.1840_conservedproteinoftheN-typeATPpyrophosphatasesuperfamily
*194643___________ +1.72 +1.570.0020.0050.0111425124534224226.2364_
192883___________ +1.19 +1.090.0130.0130.0751540418285168586.2895_conservedhypotheticalprotein
*195058___________ +1.55 +1.260.0050.0080.0231372921213173116.3378_regulatorof1,3-beta-glucansynthesis
193691___________ +1.00 +1.010.5220.2850.8852650926607266436.3875_conservedhypotheticalprotein
*192198___________ +1.58 +1.670.0030.0080.0071425922520238016.4343_conservedhypotheticalmembraneprotein
*191719___________ +1.12 +1.220.0040.0590.0042442527256298266.4841_glucoamylase
*193710___________ +1.31 +1.220.0040.0070.0192231829194271426.5308_flavohemoglobin|dihydropteridinereductase
196346___________ +1.07 +1.060.0430.0290.2001221113113128996.5775_similartoBRCA2andCip1/p21interactingprotein
*196100___________ +1.16 +1.150.0050.0090.0192164425079248516.6240_
19816____________ +1.20 +1.170.0160.0230.0431395416705163476.6708_
*196893___________ +1.40 +1.490.0020.0070.0061443820269215806.7158_
*196064___________ +1.15 +1.320.0150.1090.0145422462325713666.7608_involvedinautophagyandvacuolartargeting
*197153___________ +1.43 +1.690.0060.0230.0101633923385276256.8053_tRNAtransportreceptor
*197063___________ +1.36 +1.310.0020.0050.0073789251433494976.8490_conservedhypotheticalprotein
197578___________ -1.08 -1.070.0650.1450.0661955418051181986.8926_conservedhypotheticalprotein
PHR2_____________ +1.16 +1.060.0470.0260.325143321656815196PHR2___
*195565___________ -2.33 -2.490.0020.0060.0064081617546164016.377__
192546___________ +1.25 +1.170.0020.0040.0071874923400219526.1008_
194972___________ +1.15 +1.060.0440.0250.3071330415237140696.1557_
193413___________ +1.21 +1.100.0170.0150.1011354216388149366.2102_hypotheticalprotein
194159___________ +1.04 -1.020.7400.5560.6871807818731177176.2622_
191653___________ +1.09 +1.060.0470.0510.1091281614001135916.3138_hypotheticalprotein
192442___________ +1.24 +1.140.0040.0080.0181316016331150506.3620_hypotheticalprotein
19783____________ +1.30 +1.220.0040.0060.0181501519473183686.4113_ATPase
192810___________ +1.21 +1.160.0120.0130.0571261415249145806.4582_
195604___________ +1.11 +1.080.0430.0330.1641256413961136176.5069_
192306___________ +1.03 -1.110.5430.5690.3916739269384606226.5544_conservedhypotheticalprotein
*19729____________ +1.09 +1.170.0110.0940.0102380325849277986.6014_hypotheticalprotein
*193669___________ +3.68 +4.500.0000.0000.000725392670793263976.6480_serine/threonineproteinkinase
*193113___________ +1.36 +1.460.0010.0060.0032212630066324046.6932_conservedhypotheticalprotein
*194827___________ -1.71 -1.530.0000.0000.001169246990841109716.7384_adenylosuccinatesynthetase
*196436___________ +1.33 +1.210.0020.0030.0122539233715306876.7818_hypotheticalprotein
193269___________ +1.28 +1.250.0070.0090.0301308216769163786.8270_glucansynthase
*195466___________ -1.53 -1.560.0010.0030.0083226522103882068856.8702_ribosomalproteinS24
*195886___________ -1.36 -1.460.0020.0070.0063983829193272316.9151_vacuolarATPaseV0domainsubunitc
1973_____________ +1.05 +1.010.3980.1970.9521245213067125526.79___probablezincaminopeptidase
191238___________ +1.13 +1.130.0150.0170.0621268814391142936.712__gammatubulin
191506___________ +1.28 +1.170.0070.0090.0381272516306149516.1308_hypotheticalprotein
191528___________ +1.02 -1.040.3710.7470.2032016220474193046.1857_mitochondrialRNApolymerasespecificityfactor
*192020___________ +9.43 +8.430.0000.0000.000329593108162778386.2379_hexosetransporter
*19172____________ +1.40 +1.370.0020.0050.0081847225890252326.2908_RNApolymeraseIandIIIsubunit
191522___________ +1.19 +1.150.0080.0110.0321259714975145496.3392_
191336___________ +1.21 +1.160.0070.0100.0261621219543187416.3890_
*195508___________ +1.35 +1.320.0040.0070.0211755823640231926.4356_hypotheticalprotein
*195783___________ +1.18 +1.020.0280.0170.2183412340237347416.4855_conservedhypotheticalprotein
*196160___________ +2.41 +2.180.0000.0000.0003311479933722706.5322_
196362___________ +1.04 +1.010.2430.1100.9221411214645142456.5790_
*196085___________ -1.27 -1.720.0000.0050.0001844321452701075086.6256_60Slargesubunitribosomalprotein
19831____________ +1.20 +1.200.0180.0250.0501639219605196676.6722_hypotheticalprotein
196907___________ +1.12 -1.010.1010.0490.5272781031063274836.7171_conervedhypotheticalproteinwithWDrepeats
*196077___________ +1.19 +1.110.0090.0120.0402460529389272656.7621_conservedhypotheticalprotein
*197166___________ +1.65 +2.100.0010.0070.0021427423612299246.8066_conservedhypotheticalprotein
197051___________ +1.16 +1.250.0060.0350.0071473617036183826.8502_acetylserotoninO-methyltransferase-like|Maf-likeprotein
197593___________ +1.04 +1.050.2070.1770.2711235712836129556.8941_L-asparaginase
19105____________ -1.19 -1.170.0530.1630.0474670439351398686.390__
191616___________ +1.23 +1.130.0060.0070.0391233215222138956.1030_
191136___________ +1.28 +1.140.0080.0080.0531295016523147716.1572_
192016___________ +1.12 +1.100.0240.0190.1391765219760193576.2116_transmembraneproteininvolvedinergosterolsynthesis
*19717____________ -3.62 -3.400.0000.0000.0007425220538218706.2638_mitochondrialgroEL-typeheatshockprotein
194718___________ -1.04 -1.140.0510.3030.0332706326092237136.3153_
19757____________ +1.29 +1.210.0020.0040.0101318116956159056.3636_
*195557___________ +1.29 +1.200.0290.0780.0361250216117150256.4127_transfermannosylphosphatetooligosaccharides
194756___________ +1.21 +1.190.0090.0110.0451314415943157016.4599_conservedtransmembraneprotein
*191232___________ +3.49 +3.780.0000.0000.000287221001521085746.5085_GDP-mannosetransporterintothelumenoftheGolgi
192675___________ +1.25 +1.190.0030.0060.0161786622253211846.5559_U2-snRNPassociatedsplicingproteincontactingbranchsite
196268___________ +1.07 +1.050.1150.0640.4061339114303141176.6027_conservedhypotheticalprotein
19423____________ +1.16 +1.110.0280.0200.1711533417726170786.6492_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
193097___________ +1.02 +1.050.3570.8600.1872089212129302193616.6948_alphasubunitofpyruvatedehydrogenase
*193988___________ +1.58 +1.520.0010.0020.0031577024929239456.7402_
196420___________ +1.17 +1.150.0110.0120.0561365816046156916.7833_
193285___________ +1.15 +1.070.0160.0120.1201301614907138876.8285_MCP-domainsignaltransductionprotein
*197468___________ +2.17 +2.150.0000.0010.0011451631525312296.8719_
195870___________ +1.10 +1.030.0450.0210.5461347014854139326.9167_
*1924801__________ +2.46 +2.230.0000.0000.0002770568120618136.109__NA
192862___________ +1.30 +1.180.0050.0080.0271524219792179886.732__
192230___________ +1.32 +1.180.4601.0000.2491555120600183146.1323_transcriptionfactorrequiredforcellviability
193486___________ +1.14 +1.060.0580.0290.4171859221269196156.1873_hypotheticalconservedprotein
*192241___________ -1.46 -1.440.0090.0150.0313333322824231626.2392_
*195747___________ -1.27 -1.250.0110.0180.0332971623333236896.2926_mitochondrialSSUribosomalprotein
*195193___________ -1.92 -1.780.0010.0040.0043564218546199856.3409_benzilreductase
195211___________ +1.04 -1.030.5490.3160.7942815029197273816.3902_NADP-specificisocitratedehydrogenase
*193509___________ +1.38 +1.230.0030.0050.0181822025116224366.4369_hypotheticalprotein
*192992___________ -1.41 -1.550.0020.0100.0048987263701578546.4873_60Sribosomalprotein
*191587___________ +1.33 +1.340.0020.0050.0071688822380226816.5333_hexosetransporterofthemajorfacilitatorsuperfamily
19992____________ +1.12 +1.090.0360.0310.1281815220337197796.5806_putativeaminopeptidase
*19394____________ -1.48 -1.410.0010.0030.0056418443508455456.6270_kynureninasewithroleinNADbiosynthesis
*19524____________ +1.42 +1.270.0010.0030.0032394134007305206.6736_transcriptionalregulatorinvolvedinmitosis
196920___________ +1.09 +1.050.0600.0440.2001271213851133706.7184_hypotheticalprotein
196526___________ +1.23 +1.070.0070.0050.1021564419195167306.7634_conservedhypotheticalprotein
*197181___________ -1.28 -1.320.0030.0100.0064483835033339416.8081_hypotheticalprotein
197355___________ +1.14 +1.080.0420.0240.3031347015328145306.8515_RNApolymeraseIIholoenzymecyclin-likesubunit
*197605___________ -1.80 -1.710.0010.0010.00516294090299953856.8953_20Sproteasomebeta2subunit
641______________ +1.00 +1.010.8920.6680.9201219112223123676.410__
195615___________ -1.04 -1.050.4870.6210.3164286141026408706.1049_
*193071___________ +1.46 +1.310.0010.0030.0041743025531228576.1593_
19557____________ +1.40 +1.450.0020.0040.0051651923207239016.2136_hypotheticalprotein
*1918_____________ +1.84 +1.590.0010.0010.0041596029334253046.2652_
194321___________ +1.32 +1.200.0040.0060.0171210315937144646.3173_hypotheticalprotein
*194191___________ +2.37 +2.430.0000.0030.0012849367511693556.3648_similartoribosomalproteinL24.e.B
*195379___________ -1.91 -1.600.0000.0000.002177562930241111716.4141_sterolC-24reductase
*194311___________ -5.20 -4.950.0000.0000.00016905932511341276.4616_nucleosidediphosphatekinase
*196118___________ +1.74 +1.540.0010.0030.0041605827925247456.5099_conservedhypotheticalprotein
*192334___________ +1.13 +1.170.0080.0250.0142612629580304696.5574_membraneproteininvolvedincellwallbiosynthesis
196280___________ +1.03 +1.060.6660.5110.6041379014139146206.6039_hypotheticalprotein
19438____________ +1.07 +1.100.0510.0780.0782304824593254436.6507_conservedhypotheticalprotein
195172___________ +1.19 +1.130.0150.0240.0411347216027152356.6963_secretedlipase
194000___________ +1.02 +1.010.9910.9320.9342315223671234846.7413_homeoboxtranscriptionfactor,positiveregulatorofPHO5andothergenes
196404___________ -1.03 -1.040.3940.7580.2182163420990208456.7850_glutathionesynthetase
195311___________ +1.17 +1.090.0110.0100.0871363415967148956.8298_
197482___________ -1.05 -1.070.2050.3220.1572359722479221046.8734_hypotheticalprotein
193206___________ +1.13 +1.090.0160.0140.0861530217296166546.158__
194488___________ +1.28 +1.160.0100.0110.0481409917979163056.752__
191343___________ +1.20 +1.160.0130.0190.0381345916148156626.1345_
192232___________ +1.00 -1.210.1670.7700.0827647176802631206.1888_ribosomalproteinL11A
194569___________ +1.13 +1.110.0260.0260.0931270414394141006.2407_putativeesterase/lipase
191204___________ +1.35 +1.400.0040.0080.0161471019867205316.2941_clathrinassociatedAP-3proteincomplex,mediumsubunit
*192190___________ +1.14 +1.120.0180.0410.0312392627311266956.3424_
192510___________ +1.43 +1.220.0020.0050.0081478721116179856.3915_tubulinfoldingcofactorD
*192873___________ +1.96 +2.120.0010.0040.0031473228902312106.4383_
191325___________ -1.03 -1.150.0280.9040.0152257321970196606.4887_gamma-glutamyltransferase
191393___________ +1.08 +1.120.0260.0300.0751576817052176366.5346_
196369___________ +1.08 +1.050.1140.0670.3611244813462130736.5820_
195090___________ +1.15 +1.100.0180.0140.1321377415787152086.6285_
19537____________ +1.10 +1.050.0940.0510.4021232813500129156.6749_hypotheticalprotein
*193302___________ +4.20 +3.690.0000.0000.0001038164356623829046.7197_hypotheticalprotein
196512___________ +1.10 +1.030.0910.0480.4241267213896130576.7647_
197194___________ +1.14 +1.080.0630.0640.1301656018933178466.8094_cytochromecoxidase
*197367___________ +1.13 +1.040.0450.0200.6984848854956505056.8527_ubiquitin-specificprotease
197618___________ +1.10 -1.050.5990.3420.9434189246010400276.8966_conservedhypotheticalprotein
195043___________ +1.35 +1.300.0030.0050.0111292617399167616.428__
191536___________ +1.36 +1.410.0030.0060.0111292117563181716.1062_
191164___________ -1.05 -1.080.0560.2870.0382528624025233206.1613_
191080___________ +1.15 +1.160.0090.0140.0321516017460175656.2151_
191778___________ +1.20 +1.150.0070.0100.0321302615617149636.2666_hypotheticalprotein
194723___________ +1.32 +1.100.0370.0190.4091267316723139426.3185_flavinadeninedinucleotide(FAD)synthetase
19764____________ +1.45 +1.350.0010.0040.0051348019603181776.3666_
*191684___________ +1.40 +1.300.0010.0030.0092130629838277886.4155_
*195710___________ +1.89 +1.960.0000.0010.0012487946932488026.4638_
196238___________ -1.11 -1.170.0040.0170.0072079318773177776.5118_
192320___________ +1.34 +1.360.0070.0150.0171299817382176716.5587_
194937___________ +1.14 +1.070.0560.0360.2501255514350134926.6052_
*196625___________ +1.52 +1.530.0010.0030.0042202633580337516.6522_lowsimilaritytonuclosomeassemblyfactor
*195161___________ -1.94 -2.000.0010.0020.0025448428121271926.6975_mitochondrialribosomalproteinofthelargesubunit
*194013___________ +1.16 +1.100.0090.0110.0433564841510393876.7426_conservedhypotheticalprotein
67868____________ +1.11 +1.020.1180.0520.7101243913779127106.7868_
*195323___________ -1.26 -1.680.0010.0120.0017276857584433976.8312_mitochondrialmalatedehydrogenase
197494___________ +1.07 +1.060.0690.0520.1971314914058139366.8745_
194287___________ +1.05 +1.050.2600.1880.3681574216458165906.172__alcoholdehydrogenase
19424____________ +1.04 +1.100.0930.1140.1271605116699175896.770__
195572___________ -1.02 +1.010.8490.8660.6307849177261791686.1361_mannosyltransferase:vanadateresistanceprotein
19856____________ +1.24 +1.090.0030.0030.0521623420072177116.1905_probableflavin-containingmonooxygenase
195068___________ +1.30 +1.260.0050.0060.0291255516307158786.2426_
194494___________ +1.11 +1.120.0300.0610.0451265014015141516.2954_
191170___________ +1.27 +1.240.0050.0100.0181329316862165256.3439_chorismatemutase
196023___________ +1.55 +1.380.0020.0040.0061470822846202946.3927_conservedhypotheticalprotein
*64399____________ +1.46 +1.330.0060.0090.0221811926424241616.4399_
194791___________ +1.33 +1.270.0030.0050.0161388718507175966.4900_
6536_____________ +1.22 +1.160.0080.0090.0441407617174162906.5360_
*193869___________ +1.49 +1.530.0030.0070.0081570023373240996.5840_
*195073___________ -1.58 -1.620.0000.0000.00015417297766954256.6303_dolichol-P-mannosesynthesis
196654___________ +1.29 +1.220.0060.0090.0211473918979180066.6763_possiblemembraneprotein
193315___________ +1.13 +1.090.0120.0120.0781387915747151176.7210_transactivatorprotein
195280___________ -1.30 -1.300.0010.0040.0042790721444214246.7662_highaffinitymethioninepermease
*197206___________ +1.16 +1.180.0020.0060.0072372227447279716.8106_conservedhypotheticalprotein
197379___________ +1.14 +1.050.0230.0130.3381445416466151096.8539_long-chain-fatty-acid--CoAligase
197632___________ +1.02 +1.010.3560.2850.3801662717029168246.8980_conservedhypotheticalprotein
194346___________ +1.07 +1.070.1370.1170.2241498816105160686.446__

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
196489___________ +1.17 +1.160.0050.0120.0151813821289210056.1075_
*192665___________ +1.37 +1.320.0020.0030.0192513434414330666.1629_
*191011___________ +1.31 +1.220.0010.0010.0042590033925315446.2169_alpha-1,2-mannosyltransferase
19238____________ +1.08 -1.000.6160.3600.8792494126956248406.2684_
*193218___________ +1.39 +1.380.0040.0070.0141394819388193166.3199_conservedhypotheticalprotein
195224___________ +1.45 +1.440.0020.0060.0051362919760195896.3685_ser/thrproteinkinase,phosphorylates,activatesYPK1
191382___________ -1.04 +1.000.8840.6460.9982639425348264436.4168_golgiuridinediphosphate-N-acetylglucosaminetransporter
193545___________ -1.01 -1.010.6160.5250.5101844218301181736.4656_
193914___________ +1.14 +1.060.0250.0180.1511326415057140686.5134_
191934___________ +1.12 +1.050.1620.1140.3092420427128253836.5604_
194172___________ +1.10 +1.040.0430.0210.4241292514213133976.6066_p-nitrophenylphosphatase|4-nitrophenylphosphatase
196639___________ -1.00 -1.040.5710.5670.4232160421587207666.6536_cpnservedhypotheticalprotein
196840___________ +1.16 +1.040.0260.0140.3601267514749131856.6988_
194026___________ +1.07 +1.020.3130.1610.6911546816579157566.7439_ATPphosphoribosyltransferase
194585___________ +1.16 +1.080.0230.0170.1461637919067177316.7884_transcriptionfactorTFIIFlargesubunit
*195338___________ +2.08 +2.210.0000.0010.0002841059069627376.8327_potentialfungalZn(2)-Cys(6)binuclearclusterdomainsimtothatofGAL4
*197507___________ +1.57 +1.590.0070.0100.0333211850315511276.8759_conservedhypotheticalprotein
191765___________ +1.21 +1.270.0050.0130.0121279415417161956.189__
*194212___________ +4.19 +4.570.0000.0000.000562672355182568866.790__
*192355___________ +1.58 +1.490.0010.0050.0032234835304333876.1376_
*192447___________ +1.76 +1.700.0010.0030.0021930033961328336.1920_phosphatidylinositolkinaseinvolvedinactinorganization
192282___________ +1.22 +1.130.0100.0090.0761513218425170786.2442_
194409___________ +1.35 +1.380.0050.0150.0091362218435187586.2974_
195210___________ +1.15 +1.150.0210.0330.0481785020561205116.3453_transcriptionfactor
195291___________ +1.09 +1.060.0770.0420.3611770319364187076.3943_inositolphospolipidbiosynthesis
*194051___________ -1.41 -1.660.0000.0010.0004512031943271436.4416_
*195734___________ -1.34 -1.620.0000.0020.0006038145064373196.4913_glucosederepression
*192143___________ +1.95 +2.260.0010.0030.0022140241756483626.5375_
*193885___________ +2.01 +2.410.0010.0050.0031371427551331146.5856_hypotheticalprotein
*194388___________ -1.21 -1.450.0030.0260.0048158067308562596.6319_TBP-complexedprotein(TAF2)
*196670___________ +1.18 +1.090.0240.0170.1602652631214288066.6779_chromatinassemblyfactor
*19339____________ -1.87 -2.160.0000.0000.0002282991218061057186.7223_mitochondriadirectedNADHdehydrogenase
*195267___________ +1.71 +1.230.0020.0020.045940511612791160746.7675_hypotheticalprotein
197218___________ +1.11 +1.020.6290.4670.5981473231631351508266.8118_homologytoplantPR-1classofproteins
*197391___________ -1.29 -1.610.0000.0110.0016284848856390706.8551_membrane-boundalpha-1,6-mannosyltransferase
*197648___________ +1.54 +1.590.0000.0030.0012517338884400126.8997_
19578____________ +1.11 +1.140.0550.0760.0882696329915307296.467__
*191613___________ +1.54 +1.530.0000.0020.0012140432896326576.1091_
*193145___________ +3.09 +2.710.0010.0020.0021448944730393176.1642_MajorRepeatSequence
*19658____________ +1.60 +1.420.0020.0060.0081524624402216966.2188_
*192720___________ +1.63 +1.440.0010.0020.0042190035674315976.2700_
19467____________ +1.12 +1.070.0410.0360.1321240713845133046.3215_
1989_____________ +1.12 +1.120.0200.0230.0701644118334184656.3701_
195489___________ +1.28 +1.270.0010.0030.0041467018802185966.4183_hypotheticalprotein
*192571___________ +1.35 +1.070.0040.0030.3711494722025301600646.4672_GTP-bindingproteininvolvedintransportandfusionofpost-Golgisecretoryvesiclestotheplasmamembrane
*193901___________ -1.15 -1.190.0080.0270.0133137927296262736.5147_coenzymeF420-dependentN5,N10-methylenetetrahydromethanopterinreductaseandrelatedflavin-dependentoxidoreductase
*191856___________ +1.52 +1.570.0000.0010.0003984760690626516.5623_histonedeacetylaseandtranscriptionalregulator
192184___________ +1.15 +1.140.0080.0190.0202103224149238986.6079_degradationofaromaticcompounds|2-keto-4-pentenoatehydratase/2-oxohepta-3-ene-1,7-dioicacidhydratase(catecholpathway)
*196653___________ -1.84 -1.860.0000.0010.0017210939241388446.6550_GTPbindingprotein
*196852___________ +2.30 +2.290.0000.0000.0002640960712605156.7001_conservedhypotheticalprotein
194041___________ +1.00 -1.070.6370.9090.3911923219275180206.7455_
194600___________ -1.03 -1.050.4880.6330.3131504014600143436.7899_conservedhypotheticalprotein
195353___________ +1.13 +1.120.0190.0350.0401392815783156616.8343_
*197521___________ +1.38 +1.350.0010.0020.0022243631002303456.8773_conservedhypotheticalprotein
195381___________ +1.42 +1.400.0020.0080.0061545021925216366.206__
*191174___________ +1.30 +1.350.0060.0370.0084530859021612136.814__diphthamidebiosynthesis
192431___________ +1.31 +1.190.0030.0040.0301300816982155376.1394_hypotheticalprotein
191608___________ +1.30 +1.210.0060.0080.0271229015985148456.1934_hypotheticalarylsulfatase
*196260___________ +2.26 +2.340.0000.0010.0014116092983961596.2457_ubiquitinC-terminalhydrolase
*19789____________ +4.46 +6.410.0000.0010.0001497466787960556.2988_
191115___________ +1.49 +1.370.0020.0050.0081492622221204546.3467_guanylatekinase
193760___________ +1.11 +1.170.0200.0540.0301328314761155686.3959_
*195591___________ -1.54 -1.380.0230.0330.0564283627820309876.4433_adenosinekinase
191062___________ +1.37 +1.210.0050.0050.0381452119926175926.4927_conservedhypotheticalprotein
*196171___________ +2.62 +2.780.0000.0000.0002720271279756886.5393_
*193133___________ +3.03 +3.890.0000.0000.0002341170923911326.5870_mitochondrialglycerol-3-phosphatedehydrogenase
*195117___________ +1.83 +2.420.0010.0080.001674231234611632476.6334_
*196685___________ +1.14 +1.130.0080.0180.0192817431991318476.6794_pre-mRNAsplicing
*19352____________ +1.18 +1.160.0040.0070.0132632531176306306.7236_hypotheticalprotein
*195255___________ -1.29 -1.400.0030.0290.0044157432155296016.7687_peroxisomalABCtransporter2
*197232___________ +1.67 +1.940.0020.0050.0051412023572274556.8133_cohesincomplexsubunit
*197404___________ +1.21 +1.310.0010.0040.0014354352712572136.8564_L-serine/L-threoninedeaminase|catabolicserine(threonine)dehydratase
197664___________ +1.03 +1.150.1400.9050.0674675148030538156.9012_zincfingerprotein
*191119___________ +1.35 +1.400.0010.0030.0012441332861341996.488__
*194775___________ +1.50 +1.540.0000.0010.0002788641691428806.1107_
*193153___________ +2.75 +2.560.0000.0000.0002430966865623116.1660_phosphatidylinositol4-phosphatekinase
*196249___________ +1.48 +1.320.0010.0040.0041767626149232916.2201_highaffinitypotassiumtransporter
19644____________ +1.39 +1.160.0030.0030.0461319818338153516.2715_high-affinityglucosetransporterorsensor
*193939___________ +1.31 +1.430.0010.0040.0021719722596246486.3226_
196477___________ +1.19 +1.160.0080.0110.0351479117630171906.3717_conservedhypotheticalprotein
*192353___________ +2.55 +2.540.0000.0000.0002469962955626376.4199_highlyconservedhypotheticalprotein
192585___________ +1.10 +1.120.0110.0120.0571361914964152786.4686_hypotheticalprotein
*19211____________ +1.23 +1.230.0010.0030.0023745646089458976.5162_probablezincfingersimilartobacterialAdaDNA-protein-cysteinemethyltransferase
*19321____________ +1.21 +1.350.0070.0660.0075863971044792956.5637_verylowaffinitymethioninepermease
*192170___________ +2.09 +2.300.0000.0020.0021381328938317226.6092_
19672____________ -1.09 +1.000.8500.5980.9794191138344419716.6565_pre-mRNAsplicingfactorRNAhelicaseofDEADboxfamily
196864___________ +1.19 +1.140.0110.0130.0531335415920152006.7013_conservedhypotheticalprotein
*192089___________ -1.21 -1.170.0100.0140.0344154334203356016.7466_synaptobrevin(v-SNARE)
*194614___________ +1.25 +1.320.0060.0110.0191430717828188736.7912_
*195369___________ -1.59 -1.570.0010.0010.0037592447786483016.8358_uroporphyrinogendecarboxylase
197539___________ +1.10 +1.110.0050.0100.0131868920518206816.8791_hypotheticalprotein
195056___________ +1.16 +1.250.0060.0230.0101342015577167886.18___
196476___________ +1.12 +1.140.0170.0490.0261247613971141916.509__
19839____________ +1.08 +1.100.1130.2280.0951500716279164416.1125_
*192823___________ +1.85 +2.000.0010.0080.0012008637082401126.1681_
196474___________ +1.31 +1.120.5190.4470.4433698148398413636.2217_
194197___________ +1.03 +1.030.3650.2750.4141459015037150076.2737_
195568___________ +1.06 +1.130.0220.0980.0221271713537144226.3243_hypotheticalprotein
*193086___________ +1.23 +1.380.0100.0310.0181287615881178036.3736_
*193751___________ +1.67 +1.460.0010.0020.0041410823594205336.4216_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*192730___________ +1.32 +1.350.0050.0150.0101523020167204906.4700_
*192414___________ -1.44 -1.800.0000.0050.0013456724041191916.5179_
193976___________ -1.02 +1.010.7900.9130.5431267012426128226.5652_hascoiled-coildomain;mitoticnuclearmigration
192911___________ +1.15 +1.250.0080.0540.0101236314165154236.6111_
*192769___________ +3.31 +2.610.0090.0220.0201072303553912798206.6583_hypotheticalprotein
*191893___________ +1.60 +1.490.0010.0040.0031747327886260566.7027_hypotheticalprotein
192074___________ +1.11 +1.080.0190.0170.0971227213665132506.7481_hypotheticalprotein
194627___________ +1.13 +1.120.0100.0220.0221420816037159256.7926_nuclearporeprotein
197291___________ +1.02 +1.090.2780.4630.1801609616387175616.8372_translationalrepressorofGCN4
196826___________ +1.05 +1.030.3070.1910.4861292513597132636.8806_
Cachs3___________ -1.26 -1.190.0040.0120.0081173993489901Cachs3_
*194315___________ +1.62 +1.560.0020.0070.0041339621732208716.221__
*191658___________ +2.35 +2.600.0000.0010.0011655638941431026.833__
192620___________ +1.11 +1.150.0920.1790.0861891121020216996.1411_
193520___________ +1.16 +1.360.0730.5300.0392839532985385526.1953_
192160___________ +1.31 +1.350.0030.0120.0071277616713172396.2475_
*191093___________ +1.58 +1.930.0010.0050.0032081332860401206.3003_
194273___________ +1.14 +1.080.0600.1140.0701478516928160306.3484_putativemitochondrialintegralmemebraneprotein
194244___________ +1.10 +1.070.4680.3550.4721463816111156216.3980_hypotheticalprotein
19310____________ +1.04 +1.010.5710.5390.4401379214412138756.4450_
*195843___________ +1.35 +1.730.0070.1190.0061966326555339946.4945_hypotheticalprotein
*196188___________ +1.40 +1.470.0200.1150.0192694237596396606.5409_hypotheticalprotein
*192260___________ +1.37 +1.490.0010.0050.0012039827871304876.5886_BoxC/DsnoRNAaccumulation
*192012___________ +1.25 +1.250.0490.2060.0382396429992300076.6349_
196701___________ +1.03 -1.020.4120.2270.7047813280480768866.6810_proline-tRNAligase
194440___________ -1.06 -1.090.2660.1400.6054091438563375366.7253_ConservedOligomericGolgicomplex3secretion(golgiretention)deficient|requiredforvesicletetheringtotheyeastGolgiapparatus
*195242___________ +1.70 +1.850.0010.0050.0021699828822314556.7700_
*197247___________ +1.98 +1.890.0000.0020.0023293265245622946.8146_
*197419___________ +2.30 +2.230.0000.0010.0002445856173546456.8579_diadenosinepolyphosphatehydrolase|memberoftheFhithistidinetriadfamily
*197680___________ -1.26 -1.620.0420.1320.04012373997988764076.9028_transcriptionalactivation
*192415___________ -1.47 -1.620.0000.0020.0014075727645252176.39___
*19738____________ +2.00 +2.270.0000.0000.0003354567092762436.529__
*193378___________ +2.56 +2.100.0000.0010.0021400135888293796.1151_
194334___________ +1.11 +1.090.0160.0230.0451269614127139006.1697_
191801___________ +1.05 +1.170.1910.9670.0924412346216518406.2233_cytochrome-b5reductase
193638___________ +1.16 +1.110.0240.0350.0531279214840141406.2753_hypotheticalprotein
*194326___________ +1.86 +1.880.0010.0060.0041468227356276366.3259_
*19843____________ -1.14 -1.140.0410.1010.0473556831174312346.3751_DNArepairexonuclease
*194896___________ +1.31 +1.390.0010.0070.0012784836400386636.4232_RNApolymeraseIsubunit
*194662___________ +1.55 +1.590.0000.0020.0012328836063371396.4712_
*194293___________ -1.23 -1.320.0170.0190.0643371027453255276.5193_WDrepeatprotein
196148___________ +1.21 +1.310.0020.0080.0051414717055184826.5664_
*192898___________ +2.02 +1.910.0000.0010.0002129443035406716.6124_highlyconservedhypotheticalprotein,putativeaniontransporter
*194248___________ -1.71 -1.670.0010.0020.00713890381143833676.6596_
*191880___________ -2.05 -1.880.0010.0020.0045491526759291656.7040_ferrochelataseprecursorthatperformsthelaststepinhemebiosynthesis
*192062___________ -2.40 -2.040.0010.0020.0045803924193284226.7493_Cu/Znsuperoxidedismutase
*197015___________ -1.50 -1.770.0010.0050.00213541890161765986.7940_
*197304___________ +1.47 +1.350.0000.0010.0023923657673530576.8385_hypotheticalprotein
*196810___________ +1.70 +1.690.0020.0040.0081493425458251996.8821_similartoproteinphosphatase2AregulatorysubunitA
Cahyr95__________ -1.04 -1.030.4560.3970.403122261173411909Cahyr95
*196078___________ +1.34 +1.120.0040.0020.3733483646624388716.241__conservedhypotheticalprotein
*193213___________ +1.20 +1.490.0000.0030.0004166950211619286.847__
*196017___________ +1.35 +1.240.0010.0020.0051889525474234276.1429_hypotheticalprotein
196028___________ +1.27 +1.180.0510.0310.2671386417658163436.1969_
194070___________ +1.26 +1.150.0080.0100.0441401217640160566.2488_hypotheticalprotein
194061___________ +1.32 +1.140.0060.0090.0241697722366192966.3018_conservedhypotheticalprotein
*195188___________ +1.60 +1.380.0040.0060.0181433522872197276.3500_
192933___________ +1.40 +1.220.0050.0080.0241476320694179466.3996_
*195523___________ +1.65 +1.510.0000.0010.0022162035715327256.4465_hypotheticalprotein
*192474___________ +1.65 +1.790.0000.0010.000755541246951349206.4961_carboxypeptidaseC
*196200___________ +1.59 +1.420.0010.0020.0031874429757265926.5424_pathogenesisrelatedprotein,repressedbyTUP1protein
192245___________ +1.19 +1.090.0170.0130.1431304815539142316.5901_GTP-bindingproteinfotherabfamily
*191994___________ +1.73 +1.680.0000.0010.0003107953897521086.6365_conservedhypotheticalprotein
*194112___________ +1.89 +1.850.0000.0010.0011904435976351496.6823_
*194451___________ +1.81 +1.980.0020.0070.0061498827154296106.7266_
*196968___________ +1.84 +1.780.0010.0020.0041726431709306826.7715_
*197263___________ -1.19 -1.210.0140.0190.0445914649717490826.8163_similaritytoX-Prodipeptidases
*197434___________ +2.49 +2.700.0000.0010.0011774644200479906.8594_glycogenin|self-glucosylatinginitiatorofglycogensynthesis
*195995___________ +2.97 +2.870.0000.0010.0011734951563498726.9041_
*1956_____________ +1.27 +1.260.0120.0460.0162410830613303486.57___
194152___________ +1.17 +1.040.8200.6040.8035629866010586306.552__
*191809___________ -1.73 -2.090.0030.0110.0063565520577170946.1169_
192551___________ -1.08 -1.370.2250.2150.2516834462992497596.1715_methionine-synthesizing5-methyltetrahydropteroyltriglutamate--homocysteinemethyltransferase
192281___________ +1.22 +1.210.0040.0170.0081427917360172216.2249_3-oxoacidCoA-transferase
194225___________ +1.25 -1.010.2400.1360.5063385442242335576.2769_
192853___________ +1.04 +1.050.3640.2680.4241256413072131406.3276_
*193462___________ +2.06 +1.780.0020.0040.0063624574717643496.3765_GTP-bindingproteinoftheARFfamily|componentofCOPIIcoatofvesicles|requiredforERtoGolgiproteintransport
191840___________ +1.36 +1.020.9980.9610.97783388113610850086.4246_conservedhypotheticalprotein
*193340___________ -2.40 -3.570.0010.0040.00117443072678488786.4731_manganese-superoxidedismutase
*194279___________ +1.79 +2.210.0010.0050.0011306823441288716.5207_
196135___________ +1.08 +1.050.3680.4240.2771737518850182006.5679_conservedhypotheticalprotein
195841___________ +1.26 +1.260.0100.0200.0231697821458214756.6137_hypotheticalprotein
194235___________ +1.07 +1.090.3100.4830.2011994621246217946.6610_cyclicnucleotidephosphodiesterase
*191866___________ +1.28 +1.370.0060.0210.0111667021338228286.7054_vacuolarATPaseV1domainsubunitG
193813___________ +1.05 +1.030.7360.8010.5071491215616154136.7508_conservedhypotheticalprotein
197027___________ +1.22 +1.250.0230.0630.0311544418851193656.7953_conservedhypotheticalprotein
197317___________ +1.04 +1.110.0980.2000.0861433214913158866.8398_transcriptionalactivator,Zn-finger
196797___________ -1.05 -1.070.3900.5820.2441194311427111446.8834_conservedhypotheticalprotein
Cahydr371________ -1.09 -1.060.0770.0860.127118201086311139Cahydr3
193470___________ +1.09 +1.130.2990.5380.1822053922361232376.256__
*192125___________ -2.42 -2.370.0010.0030.0067577183128413196316.864__hypotheticalprotein
*19114____________ +1.60 +1.650.0010.0050.0021667026597274456.1446_
19690____________ +1.37 +1.360.0020.0070.0041360718597185196.1985_lysophospholipase
19101____________ +1.55 +1.480.0030.0080.0071480922961219856.2504_lowsimilaritytoaregulatorofsporulation
*193644___________ +1.83 +2.010.0010.0090.0022342342770471306.3032_
*194711___________ +1.25 +1.290.0300.0710.0412753034383356406.3510_acidicrepetitiveprotein
19698____________ +1.51 +1.380.1510.3140.109745721124101028636.4010_conservedhypotheticalprotein
193183___________ -1.05 -1.180.2380.2140.2734671044397394646.4480_hypotheticalprotein
192461___________ +1.14 +1.140.0570.2510.0411867021365212136.4974_RNApolIItranscriptioncofactor
*196286___________ +1.80 +2.220.0000.0030.0011849533220411346.5436_conservedhypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*1923_____________ -1.47 -1.070.0300.0130.721113495773821061106.5917_putativetransporterorflippaseupregulatedduringtheacquisitionofazoleresistance
*191415___________ +3.24 +4.220.0000.0020.0001004723254384242446.6384_ferricreductase
*194096___________ -1.25 -1.400.0030.0090.0063030224277216576.6840_acyltransferasesimilartohumanBTHSgeneinvolvedinBarthsyndrome
19898____________ -1.17 -1.200.0140.0200.0432246419169187856.7279_delta-aminolevulinatedehydratase(porphobilinogensynthase)
196981___________ +1.25 +1.400.0040.0180.0061262015789176116.7727_conservedorganicsolutetransporter
197275___________ +1.17 +1.060.5160.3270.6364304850283457046.8176_
197447___________ +1.13 +1.090.0330.0360.0901299714624141426.8607_carboxylicacidtransporterprotein
195982___________ -1.02 -1.040.3230.2310.4111513614814146136.9056_
678______________ +1.15 +1.090.0070.0060.0841281614776139516.78___
192013___________ +1.35 +1.220.0020.0030.0131313217713160626.572__
61186____________ +1.23 +1.110.0100.0090.0911243315257137716.1186_
19710____________ +1.13 +1.080.0280.0190.1831529717242164726.1730_succinate-CoAligasebetasubunit
*193759___________ +2.49 +2.140.0010.0020.0041540538416329336.2265_RNApolymeraseIIElongatorproteinsubunit
1934501__________ +1.13 +1.100.0300.0430.0621549717521169956.2790_NA
193621___________ +1.21 +1.180.0040.0090.0131341016204157626.3291_
194356___________ +1.20 +1.220.0590.1280.0631326715887162036.3782_high-affinityglucosetransporter
192213___________ +1.24 +1.220.0040.0100.0131504818731183636.4258_hypotheticalprotein
192113___________ +1.15 +1.090.0300.0260.1241684719379183336.4748_integralperoxisomalmembraneprotein
194815___________ +1.05 +1.030.5210.2860.8681506015796155026.5221_microtubule-associatedprotein
19584____________ +1.02 +1.000.4930.6980.3011443114739144986.5696_cytochromecperoxidase
195828___________ +1.22 +1.260.0170.0240.0461365016694172116.6149_
195792___________ -1.01 -1.030.3810.4850.2641821818119176646.6626_alpha1,2mannosyltransferaseinvolvedinglycosylphosphatidylinositolsynthesis|proteinkinaseCpathway
19499____________ -1.55 -1.460.0050.0090.0212765217845189226.7072_S-adenosylmethionine-dependentmethyltransferase
193828___________ +1.08 +1.040.1860.1160.3941245613453129106.7523_hypotheticalprotein
197041___________ +1.10 +1.070.0310.0510.0571359214932145716.7966_
*197329___________ +1.16 +1.080.0140.0110.1072453928572265956.8410_E2ubiquitin-conjugationenzyme
*196785___________ -1.91 -1.960.0000.0020.0017594439830387876.8846_acidicribosomalproteinS12
42995____________ -1.02 -1.020.4180.3440.4041229012025120844.2995_
*19223____________ +1.60 +1.470.0040.0070.0151457823374213986.277__
*191682___________ -1.07 -1.200.0220.0560.0322797826139233876.889__conservedhypotheticalprotein
*191493___________ +1.65 +1.620.0000.0010.0002121634988343326.1462_nucleotideexcisionrepairprotein|DNAreplicationandrepair
191676___________ +1.28 +1.150.0030.0040.0291457618629167966.1998_conservedhypotheticalprotein
192728___________ +1.38 +1.150.0570.0270.5141359318697156456.2520_cellcyclecheckpointandnucleotideexcisionrepairprotein
194522___________ +1.07 +1.020.1100.0600.4161408815082143836.3049_similartocytochromeb5
19640____________ +1.23 +1.170.0050.0070.0271343816588157106.3527_conservedhypotheticalprotein
*194754___________ +1.17 +1.190.0080.0100.0363665042877437396.4024_
192833___________ +1.24 +1.140.0060.0060.0451336816593151796.4494_hypotheticalprotein
193473___________ +1.28 +1.210.0150.0170.0631386017688167256.4987_
*194683___________ +1.25 +1.180.0130.0150.0561658620803195046.5452_
19199____________ +1.01 +1.010.6310.8250.3961849318699186016.5931_hypotheticalprotein
191429___________ +1.17 +1.150.0190.0260.0531555818256179126.6398_proteinwithpresumedroleinDNArepairorrecombination
*194084___________ +1.20 +1.310.0030.0100.0064762357161621946.6852_cAMP-activatedproteinkinase|glucoserepressionprotein
*19882____________ +1.20 +1.230.0060.0130.0151933823295238496.7294_
*196993___________ +2.86 +2.400.0000.0010.0011815651890435656.7739_generalaminoacidpermease
19941____________ +1.05 +1.030.0670.0480.2151272513370131466.8190_phosphatidylinositoltransferprotein
*197459___________ +2.80 +3.150.0000.0000.00033557939301058176.8619_similartogeneralchromatinfactor
195968___________ +1.19 +1.170.0100.0110.0621419116880166136.9069_RhoGDPdissociationinhibitor
194171___________ +1.08 +1.100.0470.0800.0671253013484137456.101__
192031___________ +1.18 +1.080.0280.0240.1191218814352131566.595__
19750____________ +1.10 +1.110.0300.1440.0271319514452146576.1207_hypotheticalprotein
191181___________ -1.00 +1.020.4430.5170.3121448614454147076.1747_diacylglycerolpyrophosphatephosphatase
19473____________ +1.06 +1.100.7390.4670.9661301013842143086.2282_
194350___________ -1.00 +1.010.8890.9050.6801256412564126626.2806_proteinphosphatase2A
193658___________ +1.01 +1.050.6570.7260.4461335613537140386.3304_
191020___________ +1.01 +1.040.5580.8210.3341204712196125596.3800_
192612___________ +1.15 +1.100.0950.1180.1281456016674159756.4273_zincfingerproteinsimliartoSWI5
64763____________ -1.05 -1.070.0590.1430.0581229211698114736.4763_
194136___________ +1.01 +1.050.5110.6710.3231175811834123196.5240_
192980___________ -1.03 -1.040.2600.3120.2191190211535114486.5710_
192481___________ -1.06 -1.050.1440.2730.1131217711441115806.6163_
195806___________ -1.14 -1.160.0750.3590.0461506813234129756.6641_
19485____________ +1.00 -1.000.9880.9450.9031375013765137216.7086_spindlepolebodycalcium-bindingproteincomponent
193844___________ -1.02 +1.030.7360.7610.5211224512007126046.7539_mitochondrialribosomalprotein
195029___________ -1.00 -1.010.8770.7920.7081195111930118636.7980_putativemembraneprotein
197343___________ -1.00 -1.020.4770.9830.2611221612200119396.8424_pre-mRNA-processingU4/U6smallnuclearribonucleoprotein,snRNP
196773___________ -1.03 -1.060.1490.5220.0831187211538111776.8859_
42442____________ +1.02 +1.020.4230.4320.3341205212308123054.2442_
191368___________ +1.10 +1.040.9600.7980.9593398737509352926.291__hypotheticaloutermembranelipoprotein
191294___________ +1.24 +1.290.0020.0060.0051472618301189336.911__
193627___________ +1.22 +1.180.0120.0450.0181590319403187156.1478_
19261____________ +1.29 +1.180.0140.0210.0401264616282149766.2014_
194769___________ +1.07 +1.060.2240.2110.2531290513817137146.2538_
193789___________ -1.02 -1.120.4830.3140.5846217761182556846.3062_ribosomalproteinL24A(rp29)(YL21)(L30A)
19867____________ +1.06 -1.010.9900.9810.9021835119365181606.3547_
*195818___________ +4.68 +5.090.0000.0010.000246201151541254046.4041_sphingosinehydroxylase|requiredforthehydroxylationofC-4ofthesphingoidmoietyofceramide
195640___________ -1.04 -1.120.1900.2670.1652760626540245596.4509_peroxisomalproteinreceptor
1947_____________ +1.08 +1.070.0840.1100.1161318914185140636.5001_hypotheticalprotein
193736___________ -1.03 -1.010.5180.3050.7231947218880192656.5466_
195148___________ +1.07 +1.130.0210.0600.0281244713354141016.5945_
*191551___________ -1.73 -1.870.0030.0070.0114314024940231166.6409_hypotheticalprotein
*196717___________ +1.22 +1.350.0080.2650.0062624831982353096.6866_dihydrofolatereductase
196922___________ +1.03 +1.010.8840.7490.7551246412779125606.7308_chromosomalDNAreplicationinitiationprotein
193015___________ +1.07 +1.060.0710.0630.1621636617578173156.7752_conservedhypotheticalprotein
19955____________ +1.09 +1.050.1180.1020.2091357014803142716.8204_hypotheticalprotein
195397___________ +1.07 +1.050.1690.1900.1861325514138139606.8632_
195956___________ -1.08 -1.150.0410.0590.0732526523436220136.9080_
*196888___________ +1.52 +1.500.0000.0010.0012035131015304446.122__
191007___________ +1.30 +1.170.0030.0050.0231311617005153846.613__inositolpolyphosphatekinase
191087___________ +1.45 +1.260.0030.0050.0161421720679179246.1223_
*194690___________ +4.39 +3.580.0000.0010.0011512066444541496.1770_
193935___________ +1.08 +1.100.0280.0270.0971172812627128616.2298_hypotheticalprotein
*194426___________ -1.16 -1.260.0050.0350.0072871024791227236.2828_peroxisomalintegralmembraneprotein
195041___________ +1.30 +1.190.0040.0070.0181370417759163496.3318_hypotheticalprotein
192565___________ +1.62 +1.480.0030.0060.0101312521199193876.3815_
*193541___________ -1.53 -1.320.0050.0050.0678380154629633236.4287_transcriptionalreleasefactor
*195620___________ +1.97 +2.170.0000.0010.0003520969266764066.4779_
*193867___________ +1.26 +1.440.0020.0120.0041839423228264116.5257_ribosomal-likeproteins
191257___________ +1.08 +1.060.0850.1670.0831257613573133046.5724_hypotheticalprotein
*192498___________ +1.58 +1.430.0020.0060.0082579640869367656.6178_
192961___________ +1.23 +1.320.0060.0150.0161449817904191866.6655_zinc-fingerprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*191470___________ -1.34 -1.480.0040.0110.0125726742698387796.7103_40SsmallsubunitribosomalproteinS26A
196569___________ +1.13 +1.070.0330.0230.1931220413769130436.7557_purinenucleosidepermease
195015___________ +1.37 +1.200.0070.0090.0291411519324169506.7994_myosin1isoform
*197116___________ +1.46 +1.470.0000.0010.0023497851176513146.8436_
*196758___________ +1.36 +1.510.0000.0020.0012460833366370426.8873_similartomammalianaldo/ketoreductases
42706____________ +1.01 +1.010.6490.3820.9681222612366123274.2706_
192251___________ +1.40 +1.200.0080.0080.0601289818095154886.307__
191532___________ +1.32 +1.180.0490.0840.0691287217007152016.932__mitochondrialoutermembraneimportreceptorsubunit|translocase
*192801___________ +1.60 +1.660.0000.0020.0012097933505347416.1497_
*193521___________ +1.61 +1.330.0020.0020.0161703427400227406.2034_adrenodoxinoxidoreductase
193780___________ +1.46 +1.230.0040.0050.0201293818852159056.2552_
*191221___________ +1.16 +1.140.0150.0290.0322370627452269656.3077_mannosyltransferase
*192278___________ +1.26 +1.320.0010.0040.0033352242206443066.3563_
193922___________ -1.19 -1.020.3170.2050.4652070117423203956.4054_suppressorofdeletionofTFIIS
*196214___________ -1.33 -1.150.0050.0050.0494276232244371386.4527_
194206___________ +1.24 +1.110.0210.0210.0831258015559140186.5016_
*192691___________ +1.35 +1.450.0010.0040.0025139569526747106.5479_
195137___________ +1.13 +1.090.0270.0260.1011200813612131366.5961_hypotheticalprotein
*191567___________ +1.69 +1.650.0020.0060.0071392923579229156.6424_vacuolarcarboxypeptidaseY
196730___________ +1.10 +1.160.0190.0310.0441950021503226036.6879_conservedhypotheticalprotein
196936___________ +1.21 +1.150.0220.0280.0621276415459146416.7321_
193029___________ +1.32 +1.240.0040.0050.0221409518539175396.7765_
*19969____________ -2.63 -2.570.0000.0000.000259718988181012256.8218_ribose-phosphatepyrophosphokinase
195412___________ +1.13 +1.120.0050.0130.0122247125410252166.8648_conservedhypotheticalprotein
195941___________ +1.07 +1.110.1420.1630.1672841230277314176.9096_ERvesicleprotein|componentofcopiivesiclesinvolvedintransportbetweentheERandgolgicomplex
19158____________ +1.40 +1.370.0010.0070.0031561821884214256.136__cellstructure:actinpatchlocalization|weaksimilaritytopotatosucrosecleavageprotein
191023___________ +1.08 +1.060.1110.3740.0701201012943127186.644__hypotheticalprotein
19921____________ +1.21 +1.160.0320.0590.0511513818301176216.1243_
193364___________ +1.62 +1.550.0710.1840.0624510873250697496.1785_hypotheticalprotein
191040___________ +1.03 +1.050.5360.5970.3711369314057143296.2317_
194962___________ -1.00 +1.030.5190.4230.4681317413142135406.2843_hypotheticalprotein
194888___________ +1.10 +1.100.3900.7460.2161569817285173216.3332_hypotheticalprotein
194870___________ +1.02 +1.070.2260.4670.1401287613125137586.3829_
19290____________ -1.00 +1.010.7540.7180.5611178911777119156.4303_
*192685___________ +1.99 +1.880.0020.0070.0031716634184322396.4795_hypotheticalprotein
*196544___________ +1.47 +1.600.0040.0120.0101402020576224116.5269_
191661___________ +1.10 -1.000.9310.7470.9082290725167228436.5736_RNAhelicaseinvolvedinmRNAexport
195762___________ -1.05 -1.000.3740.2080.6511205011524120146.6196_hypotheticalprotein
192948___________ +1.00 -1.050.4650.3620.4561583315840151466.6668_glutamineamidotransferase
191456___________ -1.01 +1.010.8140.5650.8891216012064123016.7117_hypotheticalprotein
196583___________ -1.02 +1.020.8640.7090.7521161011431118886.7571_conservedhypotheticalprotein
195001___________ +1.06 +1.140.0420.0790.0591282413594146076.8007_
197103___________ +1.11 +1.060.0620.0880.0911360315035144836.8450_GreatforFULLDEADboxproteinactivity
*196745___________ -1.12 -2.050.0050.1520.0043104852761851513926.8886_triosephosphateisomerase
42826____________ -1.03 -1.010.7270.4920.7801209911763119634.2826_
193271___________ +1.31 +1.150.0070.0090.0441281016806146896.324__
19187____________ +1.16 +1.190.0070.0160.0191247814476148126.949__
196629___________ +1.25 +1.220.0040.0110.0111422617762174176.1512_
*193590___________ -1.24 -1.230.0490.0380.1797620161291619266.2048_inorganicpyrophosphatase
*19105____________ +1.17 +1.170.0440.2110.0332332427273271886.2570_
*194558___________ +1.35 +1.210.0110.0430.0151831024688221816.3090_isopentenyl-diphosphatedelta-isomerase|ergosterolbiosynthesis
192208___________ -1.04 -1.040.5170.2780.9341046361010801010026.3578_
194668___________ -1.00 +1.030.5980.8540.3641639416337168606.4068_glucan1,3beta-glucosidase-likeprotein
194375___________ +1.08 +1.100.1810.2750.1511658717930181956.4540_conservedhypotheticalprotein
193327___________ +1.14 +1.120.0690.1840.0601594718218178906.5027_tRNA(m5U54)methyltransferase
*196305___________ +1.59 +1.490.0010.0030.0041836829124273896.5498_threoninealdolase
*192036___________ -1.20 -1.290.0140.0300.0293127826017242396.5975_dimericdihydrodioldehydrogenase
*191634___________ +1.78 +2.450.0000.0030.0011775631575434446.6438_conservedhypotheticalprotein
195655___________ +1.21 +1.300.0030.0260.0031839622170238956.6895_
*196950___________ +1.42 +1.390.0020.0130.0041864826469259866.7336_conservedhypotheticalprotein
*193043___________ -1.33 -1.420.0040.0100.0113036722832214166.7781_
193232___________ +1.04 +1.070.2310.2170.2581286613399137856.8232_putativetransporter
*195426___________ +1.81 +1.850.0010.0050.0041476626749273536.8662_predictedesteraseofthealpha-betahydrolasesuperfamily
195927___________ +1.13 -1.090.7500.6220.627105856119932969486.9110_ribosomalproteinS15(S21)(rp52)(RIGprotein)
*195705___________ -1.64 -1.760.0010.0040.0025152531473292406.150__
19155____________ -1.01 +1.060.8660.6210.9874348443077460706.658__
*191862___________ -4.44 -3.340.0000.0000.00024301854709728266.1262_conservedhypotheticalprotein
192169___________ +1.33 +1.200.0030.0040.0171366018189164546.1806_
*191646___________ +1.87 +1.840.0010.0040.0032242141954411696.2335_
19927____________ +1.13 +1.100.0080.0150.0261270614404140356.2861_conservedhypotheticalprotein
*194651___________ -1.36 -1.050.0110.0070.2272310861702782194146.3348_
19834____________ +1.07 +1.080.1580.0990.3652498026638268816.3845_alpha-mannosidase|glycosylhydrolase
194472___________ +1.18 +1.140.0070.0130.0191315115542149486.4315_hypotheticalprotein
19284____________ +1.08 +1.090.7580.6910.5842803030208305286.4812_
*193007___________ +1.17 +1.170.0110.0520.0152888833688336666.5282_conservedhypotheticalprotein
193581___________ +1.25 +1.150.0060.0080.0321431817834164046.5749_
*196600___________ +1.50 +1.780.0010.0040.0032133032020380516.6212_conservedhypotheticalprotein
194534___________ -1.06 +1.200.4350.8840.2357970975273954666.6680_conservedhypotheticalprotein
196866___________ +1.05 +1.150.1470.6810.0742749929010316286.7130_U1smallnuclearribonucleoprotein
196039___________ +1.04 +1.030.2480.1950.3251867519492192366.7583_syntaxin(T-SNARE)
*194987___________ +1.75 +2.020.0010.0040.0031568827451317556.8022_nuclearporeprotein
197089___________ +1.06 +1.050.0900.1000.1402392025455250366.8463_
197551___________ +1.09 +1.280.0610.3240.0397382080168941926.8899_D-arabinono-1,4-lactoneoxidase
42902____________ -1.02 -1.040.4390.9650.2351168211457112434.2902_
191956___________ +1.09 +1.100.5430.6080.3741715318634189066.342__
194230___________ -1.05 -1.020.1250.1260.1802991228509293346.967__
192819___________ +1.42 +1.190.0050.0050.0551307218528155056.1527_hypotheticalprotein
195633___________ +1.36 +1.330.0510.0260.3992136829105284066.2070_
*194871___________ +2.14 +1.880.0030.0080.0101488531804280576.2586_
*194280___________ +2.26 +2.190.0010.0020.0031810540900396316.3106_hypotheticalprotein
192606___________ -1.05 -1.060.1570.1000.3574071038839382716.3593_histonedeacetylaseA
191957___________ -1.08 -1.100.1110.1260.1502704024953245556.4082_holocytochrome-csynthase
*1951_____________ -1.72 -1.610.0000.0010.00010225559598633496.4555_accessoryfactortoEIF3
*191963___________ +1.53 +1.410.0110.0200.0311264819330178606.5042_
*196319___________ +1.31 +1.570.0010.0070.0022993139211470266.5513_
*192048___________ -3.77 -4.130.0000.0010.0018953423727216756.5987_hypotheticalprotein
191617___________ +1.10 +1.100.0260.0400.0561514116661166326.6455_
*195667___________ +1.10 +1.230.0030.0300.0043000833036368476.6908_
194856___________ +1.08 +1.070.0550.0430.1771387814971149096.7355_secretorylipase
193055___________ -1.01 +1.000.9520.7930.9141588815669159156.7793_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
193245___________ +1.10 +1.070.0900.0590.2761481216269157996.8245_rhoptryprotein
*195439___________ +1.01 +1.140.0480.5120.0264687847139535006.8675_hypotheticalprotein
*195912___________ +2.34 +2.820.0000.0000.00037034866011044666.9125_requiredfor60Sribosomalsubunitbiogenesis
193148___________ -1.06 -1.100.1210.3550.0781180811121107616.19___
19177____________ +1.34 +1.160.0070.0080.0421279317141148446.679__bindsmultipleproteinsinvolvedincellpolarityestablishment
191927___________ +1.33 +1.230.0020.0040.0141505820028184616.1278_hypotheticalprotein
61823____________ +1.23 +1.110.0100.0110.0611256815415140096.1823_
*192540___________ +1.55 +1.570.0020.0070.0051429622101224596.2349_silencingprotein,possiblehistoneacetyltransferase
193698___________ -1.14 -1.110.0120.0200.0321190510478107086.2879_hypotheticalprotein
196500___________ +1.21 +1.150.0060.0070.0361778421510204836.3365_ornithineacetyltransferase
192389___________ +1.23 +1.210.0180.0310.0401345416554163096.3858_
*193400___________ -1.24 -1.480.0010.0220.0026211250090420006.4331_3,4-dihydroxy-5-hexaprenylbenzoatemethyltransferase
*19603____________ +1.31 +1.180.0040.0070.0196456684405761246.4828_smallribosomalsubunit(SSU)processosomesubunit
*191363___________ +9.63 +8.070.0000.0000.000223122147701801176.5295_conservedhypotheticalprotein
193565___________ +1.10 +1.050.0910.0610.2711226413481129076.5764_hypotheticalprotein
194402___________ +1.06 +1.000.0650.0290.6511226013022122736.6226_hypotheticalprotein
*194546___________ +2.79 +2.360.0010.0040.0041418539577334826.6693_
*196880___________ +1.79 +1.540.0000.0010.0011835332886283306.7144_ConservedOligomericGolgicomplex4
196053___________ +1.20 +1.130.0420.0210.4201358016239153926.7597_gamma-glutamyltransferase
197139___________ +1.21 -1.060.2450.1340.5383354640689316226.8039_hypotheticalprotein
197076___________ +1.60 +1.290.3420.1730.7523071649092396276.8478_
*197565___________ +1.41 +1.370.0010.0040.0022145430215293896.8913_high-affinityglutaminepermease
p33______________ -1.01 +1.010.9310.7530.896118261166911979p33____
*193414___________ +2.85 +3.000.0000.0010.001491341399651473476.360__potentialmembraneprotein
*19475____________ +1.74 +1.820.0000.0020.0012096036368381836.986__
*19851____________ +4.10 +3.360.0000.0010.0011641267245551076.1543_regulatorofcellwallmannosylphosphorylation
*194737___________ -1.49 -1.510.0090.0150.0273510123518232756.2088_
*19130____________ +1.37 +1.300.0080.0120.0311351418492175536.2604_
191704___________ -1.15 -1.320.0110.0820.0122373520715180096.3122_
192791___________ +1.21 +1.140.0070.0110.0271303815724148896.3608_
192600___________ +1.20 +1.250.0140.0400.0231368016381170756.4098_spindlepolebodycomponent
*195691___________ +2.58 +2.300.0000.0020.0011715944237395406.4568_
195863___________ +1.04 +1.050.3370.2820.3541215612689127446.5055_hypotheticalprotein
*196338___________ +1.88 +2.060.0000.0020.0012036838216420496.5531_hypotheticalprotein
196456___________ +1.23 +1.240.0960.0650.2661368416823169316.6003_conservedhypotheticalprotein
193438___________ +1.13 +1.020.2290.1020.9282596729346265186.6467_dnaJhomologinendoplasmicreticulum
193124___________ +1.01 +1.100.5390.8980.3113654436766402216.6921_methionineaminopeptidase
*194841___________ +1.14 +1.110.0120.0170.0392580529380285626.7371_
196449___________ +1.06 +1.040.1000.0640.3031621217159168586.7805_hypotheticalprotein
193259___________ +1.25 +1.170.0060.0080.0321520718951177676.8259_signalpeptidasesubunit
*195451___________ +5.97 +6.500.0000.0010.001174501041871134846.8687_
*195901___________ +2.12 +1.970.0020.0050.0041468631088289266.9138_
*194890___________ +1.48 +1.300.0040.0060.0161440721302187616.53___
6697_____________ +1.29 +1.160.0040.0040.0481279816513148776.697__
195549___________ +1.49 +1.390.0010.0030.0071327419724184646.1294_conserevedhypotheticalprotein
194633___________ +1.04 +1.280.0800.4030.0477527978138962836.1841_NADP(+)-dependentdehydrogenase;actsonserine,L-allo-threonine,andother3-hydroxyacids
194642___________ +1.37 +1.200.0050.0070.0321324318138158536.2366_hypotheticalprotein
192884___________ -1.14 -1.040.4520.2330.9285981852536576876.2896_globalregulatoroftranscription
195057___________ +1.32 +1.190.0030.0040.0181375018186163956.3379_hypotheticalprotein
*193689___________ +1.90 +1.920.0000.0010.0021995237923383056.3876_6-phosphofructo-2-kinases
192197___________ +1.21 +1.140.0090.0100.0491246015070141806.4344_flavin-containingmonooxygenase
*191718___________ +1.58 +1.580.0000.0020.0012163534291341976.4842_hypotheticalprotein,containscysteinequintetlikeSTB5
193711___________ +1.08 +1.150.0280.0380.0671232113259142126.5309_phenolmonooxygenase
196347___________ +1.25 +1.230.0040.0100.0131524619082186976.5776_memberofthebetatransducinfamilyrequiredforpropertimingofDNAsynthesis
*196100___________ +1.11 +1.220.0220.2040.0173604140058437936.6241_cardiolipinsynthase
*19816____________ +1.74 +1.910.0000.0020.0011728230142329596.6709_
*196895___________ +1.67 +1.630.0020.0070.0061734028991282796.7159_hypotheticalprotein
196065___________ +1.03 -1.010.8220.9670.5762713627931267836.7609_conservedhypotheticalprotein
*197154___________ +1.75 +1.900.0020.0060.0041528426727290446.8055_
*197062___________ +2.67 +3.350.0010.0050.0021399337334468206.8491_DNA-directedRNApolymeraseI
197579___________ +1.02 +1.160.0700.9490.0332595026530300596.8927_conserevedhypotheticalprotein
ALS1_____________ +1.10 +1.030.7800.5140.932123601356312730ALS1___
19613____________ +1.22 +1.110.0070.0060.0831221114865135896.378__hypotheticalprotein
19769____________ +1.23 +1.240.0050.0090.0171440317774179176.1009_
*1985_____________ +2.44 +1.870.0020.0030.0151275431158237986.1558_glutathioneperoxidase
191479___________ +1.18 +1.140.0470.0400.1481307815445149256.2103_
194160___________ +1.15 +1.070.0430.0470.1041293214860138366.2624_sialoglycoprotease
191654___________ +1.09 +1.030.3340.1590.9351876420480193346.3139_hypotheticalprotein
192443___________ +1.17 +1.110.0110.0150.0391339715695148726.3621_corticalRhoGTPaseactivatingprotein
19782____________ +1.45 +1.300.0100.0170.0301257818186163266.4114_peroxisomallipase
*192809___________ -2.59 -2.260.0020.0050.0093656514132162066.4584_carnitineacetyltransferase|alcoholmetabolism
195602___________ +1.19 +1.160.0130.0120.0721303815493150626.5070_hypotheticalprotein
192305___________ +1.13 +1.050.3450.2420.4381511217091159156.5545_prefoldinsubunit2
19728____________ -1.00 -1.020.8160.6260.7511188911858116096.6015_TORbindingprotein
*193670___________ +2.94 +3.550.0000.0000.00033084973261173366.6481_galactokinase
193112___________ +1.04 +1.030.9400.8090.8431552616111159816.6933_highaffinintyzinctransporter
*194826___________ -2.27 -1.650.0000.0010.004194863858481181486.7385_mitochondrialisocitratedehydrogenase1
196435___________ +1.02 -1.020.6370.4680.6121207212341118006.7819_conservedhypotheticalprotein
193271___________ +1.11 +1.120.0290.0380.0671496416546167246.8271_
*196113___________ +1.47 +1.880.0010.0070.00161965909521161936.8704_
195885___________ +1.02 -1.030.3060.1610.6421367714005133236.9152_partofsmall(ribosomal)subunit(SSU)processosome(containsU3snoRNA)
1974_____________ +1.08 +1.070.3450.2340.4541247113449133676.80___
193193___________ +1.28 +1.210.0040.0070.0211278316342155296.715__
*191505___________ +1.70 +1.580.0010.0040.0051536326048242686.1309_
191527___________ +1.36 +1.150.0030.0040.0341312517821150896.1858_hypotheticalprotein
*192019___________ -1.59 -1.880.0010.0050.0024148126061220916.2380_mitochondrialribosomelargesubunitproteinL16
19173____________ -1.15 -1.080.0180.0320.0381156510077106766.2909_DNA-bindingtranscriptionfactor
*191522___________ +1.67 +1.410.0040.0070.0171600026640226036.3393_
191336___________ +1.02 -1.110.3830.2490.5117909680831713966.3889_
*195509___________ +1.71 +1.520.0020.0040.0063493859849529736.4357_hypotheticalprotein
*195784___________ +10.61 +10.210.0000.0000.000177041877971807496.4856_peroxisomalcopperamineoxidase
196160___________ -1.11 -1.110.0240.0810.0281167410533105196.5320_
196363___________ +1.04 -1.100.6220.6710.4302638327468238816.5792_mitochondrialribosomalproteinMRPL15(YmL15)
196084___________ -1.14 -1.170.0040.0290.0051189110455102016.6257_hypotheticalprotein
19832____________ -1.14 -1.140.0110.0340.0181164810179102526.6723_
196908___________ -1.17 -1.150.1080.4870.0601239210609107916.7172_folylpolyglutamatesynthase
196537___________ -1.15 -1.160.0250.0580.0381421412325122906.7623_conservedhypotheticalprotein
197167___________ -1.23 -1.190.1420.6260.07311872968699576.8069_
197050___________ -1.15 -1.120.0070.0240.0121167410171104556.8503_nucleolarprotein15|ribosomebiogenesis
197594___________ -1.10 -1.140.0110.0320.0191161110534101666.8942_conservedhypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*194516___________ +2.12 +2.100.0000.0020.0011516932117319066.391__
*194262___________ +2.85 +2.590.0000.0010.0012752878541713276.1031_tubulinmutant,benomyldependent
191137___________ +1.34 +1.190.0040.0060.0281341517985159326.1573_
*192969___________ -2.44 -1.860.0000.0000.0009396438473504626.2120_nucleotideexcisionrepairprotein
19718____________ +1.27 +1.140.0480.0220.5521272316104144496.2639_RNApolymeraseItranscriptionfactorcomponent
194719___________ +1.08 +1.080.0910.0810.1791535816614166326.3155_ERglucosidaseI
*19758____________ +1.17 +1.200.0040.0100.0092447728667292536.3637_similartomannose6-phosphatereceptor
*195558___________ +1.39 +1.250.0020.0040.0102194430541273926.4128_transcriptionfactor|nuclearDNAbindingprotein
*194755___________ +2.28 +1.970.0000.0000.0002766862983545706.4600_Kexinprotease|lateGolgiendoproteasethatprocessesofalpha-factor
*191229___________ +1.60 +1.490.0080.0180.0181362621852203006.5086_
192674___________ +1.16 +1.190.0090.0210.0191688819559200486.5560_hypotheticalprotein
196269___________ +1.10 +1.020.4060.2500.5751241613669126726.6028_conservedhypotheticalprotein
19425____________ -1.20 -1.240.0080.0210.0172494520803200606.6494_conservedhypotheticalprotein
*193097___________ +1.94 +2.130.0000.0000.0002905256371620036.6949_
*193988___________ +1.28 +1.250.0010.0020.0042258329008282286.7400_
*196418___________ +1.95 +2.160.0010.0040.0021644732146355586.7835_
*193286___________ +1.46 +1.470.0020.0070.0041544222468226566.8286_conservedhypotheticalprotein
*197469___________ +1.77 +1.780.0000.0000.0004583081094815836.8721_argininosuccinatesynthetase
196261___________ +1.30 +1.310.0020.0040.0111503219601196946.110__
192863___________ +1.34 +1.120.0220.0100.5961601221458180136.734__
192231___________ +1.41 +1.220.0020.0030.0151434620220175626.1324_hypotheticalprotein
193487___________ +1.45 +1.150.0040.0040.0551261218292145356.1874_hypotheticalprotein
192239___________ +1.54 +1.250.0020.0020.0171321720406164906.2393_GDP/GTPexchangefactor
*195749___________ -1.64 -2.010.0010.0030.0015828235543290686.2928_
195195___________ +1.14 +1.110.0370.0210.2912042423211226136.3411_uridylatekinase
195212___________ +1.25 +1.110.0130.0120.0781259115775139746.3903_ChromosomeSTability;involvedinmeioticchromosomesynapsis
*191791___________ +1.25 +1.310.0050.0120.0131770922149231256.4370_involvedincellgrowthandviralreplication
192992___________ +1.01 -1.140.1780.2850.1447451475148651836.4872_
*191586___________ -1.99 -1.790.0000.0000.00011546058031646126.5334_phosphatidylinositolphospholipaseC
19991____________ +1.09 +1.080.0520.0490.1351296414094140436.5807_DnaJ-likeco-chaperonerequiredforperoxisomebiogenesis
19393____________ +1.07 +1.010.3230.1540.9001566216733158816.6271_AP-3complexsubunitfunctioningingogi-to-vacuoleproteintransport
19526____________ +1.09 +1.130.0780.1280.0903755841077423516.6737_
*196921___________ +2.00 +1.800.0010.0030.0031616132354290146.7185_RNApolymeraseIspecifictranscriptioninitiationfactor
196525___________ -1.06 +1.040.4950.2820.7444116438731426866.7635_hypotheticalprotein
197182___________ +1.44 +1.390.0010.0040.0031664623952232156.8082_conservedhypotheticalprotein
197356___________ +1.17 +1.200.0100.0190.0261602718735192816.8516_hypotheticalmembraneprotein
197606___________ +1.20 +1.160.0070.0100.0301420717099164706.8954_hypotheticalprotein
196469___________ -1.01 -1.000.7750.5090.9301337713232133226.412__
194753___________ +1.40 +1.230.0040.0050.0301376919221169846.1050_
193071___________ +1.22 +1.120.0070.0070.0551344816361150836.1591_
19558____________ +1.03 +1.020.6220.3660.8781254212936127586.2137_glycerolkinase
1920_____________ +1.17 +1.070.3800.3060.3921285915082137386.2653_potentialregulatorysubunitofproteinserine/threoninephosphatase2A
194322___________ +1.18 +1.070.0370.0250.2011216614328130676.3174_
194738___________ +1.15 +1.050.0430.0230.3511199113780126146.3650_conservedhypotheticalmembraneprotein
195380___________ +1.04 +1.010.4120.3120.4381427614804143856.4142_transcriptionfactor
194312___________ +1.15 +1.060.0440.0280.2411355215612143636.4618_
196119___________ +1.33 +1.280.0040.0060.0211579420987202846.5100_hypotheticalprotein
*192333___________ +1.33 +1.740.0080.2110.0063076140954535976.5575_highlyconservedoxidoreductase
196281___________ -1.00 -1.020.6880.4840.6941219512141119196.6040_conservedhypotheticalprotein
19439____________ -1.06 -1.090.0650.1360.0681469113853135336.6508_involvedinmitochondrialhomologousDNArecombination
195172___________ +1.09 +1.080.0540.0390.2041421315449153116.6964_
194001___________ -1.10 -1.010.1680.1090.3572204619994218996.7414_serine/threonineproteinkinase,cox2pre-mRNAsplicingfactor
196403___________ -1.02 +1.030.7620.5590.7321906718655196046.7851_ERtranslocationmachinery
195311___________ +1.26 +1.080.0450.0430.1201335816839144416.8299_
197483___________ +1.30 +1.210.0150.0210.0441512119638182426.8735_nuclearexportfactor
1993_____________ -1.08 -1.070.1400.0970.2991234011397115796.159__conservedhypotheticalprotein
191105___________ +1.19 +1.130.0120.0140.0541274815156144386.753__hypotheticalprotein
*191734___________ +1.79 +1.500.0020.0030.0101678230096250936.1346_
*192233___________ -1.09 -1.230.0310.1120.0315786453018468656.1889_20Sproteasomesubunit
194568___________ +1.15 +1.130.0100.0160.0341387915998157026.2408_
191203___________ +1.30 +1.190.0230.0380.0471247816164148516.2942_suppressorofdefectinthesmallGTPaseRho3p
*192190___________ +1.24 +1.070.0390.0240.2524059250358433556.3425_
192510___________ +1.15 +1.150.0070.0140.0221322415158151666.3916_
*192875___________ +1.35 +1.200.0020.0050.0092102028476251196.4384_hypotheticalprotein,possiblyrelatedtoDNAJ
191326___________ -1.17 -1.140.0070.0260.0131173610028103116.4888_hypotheticalprotein
191394___________ +1.12 +1.010.1280.0540.8792861031970289516.5347_conservedhypotheticalprotein
196371___________ -1.23 -1.160.0110.0400.0171232610037106316.5823_hypotheticalprotein
195089___________ -1.12 -1.100.0120.0250.0271176210509106516.6287_telomerasereversetranscriptase
19538____________ -1.21 -1.130.0100.0260.019116749667103656.6750_N-acetylglucosaminyl-phosphatidylinositol(GPI)biosyntheticprotein
193303___________ -1.11 -1.120.0130.0490.0181181910611105106.7198_carboxymethyltransferase
196511___________ -1.16 -1.100.0240.0280.0731177810162107066.7649_tRNAligase
197195___________ -1.17 -1.160.0410.2710.0281184710137101996.8095_ubiquitin-proteinligase
*197368___________ +1.60 +1.390.0010.0020.0062537040629351856.8528_polyadenylatedRNA-bindingprotein|notreportedtoassociatewithpolyribosomes
197619___________ -1.17 -1.160.0070.0250.0111174810022101546.8967_conservedhypotheticalprotein
192051___________ +1.15 +1.090.0150.0110.1671528617528165926.431__
191535___________ +1.36 +1.220.0030.0040.0211558521245189886.1063_hypotheticalprotein
191815___________ +1.13 +1.140.1000.2720.0732036823117231716.1615_translationinitiationfactor6(eIF6)
*193704___________ +1.48 +1.740.0010.0030.0012345934765409036.2153_RNAhelicaserequiredfor60Sribosomalsubunitassembly
191779___________ +1.11 +1.100.3380.1750.7122880431919316056.2667_solublecellwallproteinsimilartomannoproteinMP65
194724___________ +1.22 +1.150.0050.0060.0311562819029179036.3186_pre-mRNAsplicingfactor|snRNA-associatedprotein
19771____________ +1.02 -1.060.0890.8600.0432286923248215006.3670_
191370___________ +1.08 +1.110.0340.0610.0531243113383138556.4156_
*195710___________ +1.17 +1.130.0410.0520.0826291073443709506.4639_
*196237___________ +1.18 +1.150.0060.0070.0392708331972312366.5119_RHOsmallmonomericGTPase;signaltransduction
192319___________ +1.16 +1.200.0250.0360.0591528417688182956.5590_
194937___________ +1.10 +1.070.0780.0320.9892360125894251666.6053_chitin-UDPacetyl-glucosaminyltransferase3
196626___________ +1.17 +1.130.0070.0120.0251661719414187036.6523_transposase
*195160___________ +1.50 +1.650.0040.0130.0093329449798549606.6976_ser/thrphosphataseinvolvedinG1/Stransition
194014___________ +1.24 +1.060.0310.0180.2771320516372140136.7427_proteinthataffectsbudemergence,intrachromosomalrecombination,andnucleardivision
67869____________ +1.00 +1.020.5510.3620.6311188811916121246.7869_
*195325___________ +2.12 +1.990.0000.0010.0012261047968450346.8313_
197495___________ +1.10 +1.070.0630.0660.1271338014751143196.8747_probableNADPHdehydrogenase
19807____________ +1.14 +1.090.0230.0140.2691807420657197126.173__
191128___________ +1.32 +1.190.0030.0040.0181306917302156046.773__classIImyosin|myosin-1isoform(typeIImyosin)heavychain
195573___________ +1.50 +1.280.0020.0040.0181249418766160526.1362_
*194777___________ -1.37 -1.360.0010.0060.0046264945617461456.1906_dihydroxyacetonekinase
195069___________ +1.31 +1.150.0060.0060.0531270016639146286.2427_
194495___________ +1.23 +1.100.0130.0100.1201385217000152946.2956_
191169___________ +1.38 +1.240.0020.0050.0121295917843160056.3440_conservedhypotheticalprotein
196024___________ +1.19 +1.170.1010.1590.1081432617081167196.3928_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
193199___________ +1.07 +1.170.4950.9300.2753958642402461686.4400_
194792___________ +1.19 +1.180.0090.0250.0171483217675174316.4902_hypotheticalprotein
192127___________ -1.02 -1.060.3910.9090.2062123720858201246.5361_hypotheticalprotein
193871___________ +1.10 +1.020.0820.0450.3711248013736127726.5842_hypotheticalprotein
195071___________ +1.19 +1.140.0170.0260.0421346216068152976.6304_
196656___________ +1.16 +1.080.0180.0150.1141562118050168796.6764_
*193315___________ +1.24 +1.140.0090.0080.0711931323947219536.7211_
195279___________ -1.12 -1.180.0060.0230.0102205019716187546.7663_conservedhypotheticalprotein
*197207___________ +1.80 +1.660.0000.0020.0021883833815313126.8107_ubiquitin-specificprotease;DNAreplicationregulation
*1971_____________ +1.45 +1.620.0000.0020.0012564837106414556.8540_mammalianGRASPproteinhomolog
197634___________ +1.04 -1.010.5540.3090.8811222112713120676.8981_
19655____________ +1.07 +1.040.1300.0770.3761218613054126756.447__high-affinityinorganicphosphate/H+symporter
196491___________ +1.17 +1.110.0340.0290.1321203014049134046.1076_hypotheticalprotein
195469___________ +1.11 +1.090.0430.0960.0511238213781135336.1630_
191010___________ +1.04 +1.050.2500.3330.1971311013615138296.2170_mannosyltransferaseinvolvedinO-andN-linkedglycosylation
19239____________ +1.16 +1.080.0340.0220.2121227814253132746.2685_helicasesubunitoftheRSCcomplex
193219___________ +1.08 +1.020.1640.0830.5471211813039124136.3200_phosphohydrolase
195225___________ +1.24 +1.120.0110.0090.0941426317673160246.3686_hypotheticalprotein
195477___________ +1.08 +1.030.3270.1820.6011177512685121036.4170_
195500___________ +1.03 +1.000.4490.2290.9771326413620133106.4657_nuclearproteinwithHMG-likeacidicregion
65135____________ -1.00 -1.030.5530.7170.3491294012921125346.5135_
191930___________ +1.06 +1.060.5120.2980.7331311913922138926.5608_
194174___________ +1.01 -1.020.5930.3470.8341222012289119556.6068_intracellularmembraneproteininvolvedinnucleosidetransport
196640___________ +1.07 +1.090.2520.1680.4002335725082254196.6537_trehalose-6-phosphatesynthase
196840___________ +1.02 +1.020.3500.2160.5231260612830128716.6989_hypotheticalprotein
194028___________ +1.01 -1.010.4780.2790.6891447514556143296.7440_
194587___________ -1.02 -1.060.3130.7370.1671214711965114586.7885_
195339___________ +1.02 +1.020.6500.5160.5711728617634176416.8328_hypotheticalprotein
*197510___________ +1.44 +1.480.0000.0020.0022855141002421796.8760_
6191_____________ -1.04 -1.040.3810.5290.2501197411512115276.191__
193359___________ +1.32 +1.260.0040.0060.0211418118749178226.791__
192379___________ +1.19 +1.020.1350.0610.6833963547271405986.1379_
192449___________ +1.20 +1.120.0160.0200.0531464417583164036.1923_
*192283___________ -1.87 -2.220.0000.0030.0014509924144203576.2443_catabolic3-dehydroquinasedehydratase
*194407___________ +1.57 +1.390.0020.0040.0081642525778228206.2975_
192924___________ +1.52 +1.200.0060.0050.0981320820050158896.3454_nuclearmigrationprotein
195290___________ -1.12 -1.190.0040.0130.0082461322073206066.3944_hypotheticalprotein
*194051___________ +2.44 +2.340.0000.0000.0002821868723660046.4418_
195735___________ -1.16 -1.190.0030.0160.005117661017298676.4914_celldivisioncycle
*192143___________ +2.00 +1.940.0010.0030.0031856637218359596.5376_
*193886___________ +1.60 +1.610.0010.0020.0021999331905322176.5857_hypotheticalprotein
194384___________ -1.12 -1.140.0070.0150.0191186810572104486.6321_fructosesymporter
196671___________ -1.14 -1.090.0240.0610.0341186610426108936.6780_vacuolaraminopeptidase
19340____________ -1.14 -1.130.0090.0280.0151171810249104086.7224_hypotheticalprotein
195266___________ -1.12 -1.120.0250.0990.0261335011905119196.7676_hypotheticalprotein
197219___________ -1.05 -1.070.1380.2880.1031175811155109816.8119_plasmamembraneironpermease
197392___________ -1.06 -1.090.1040.1260.1351177911074108276.8552_ATP-dependentRNAhelicaseofDEADboxfamily
197650___________ -1.15 -1.100.0200.0380.0381179410218107356.8999_
195064___________ +1.24 +1.120.0590.0430.2041528719021171056.469__mitochondrialribosomalprotein
19721____________ +1.46 +1.290.0040.0050.0211300518934168136.1093_conservedhypotheticalprotein
19918____________ +1.24 +1.080.0160.0120.1261255815552135956.1644_
62189____________ +1.17 +1.090.0220.0160.1521280014965140136.2189_
192717___________ +1.19 +1.110.0160.0160.0781264414992140046.2701_
191035___________ +1.16 +1.070.0200.0150.1521393616116149336.3216_
1991_____________ +1.18 +1.090.0180.0140.1211322715573143726.3703_conservedhypotheticalprotein
195490___________ +1.44 +1.280.0010.0040.0041473421181188116.4184_hypotheticalprotein
192573___________ +1.03 +1.020.2470.1120.9112200422622224446.4673_
193900___________ +1.05 +1.030.2100.1300.4161359714326140616.5148_
191857___________ +1.20 +1.120.0270.0170.2101519018259169646.5624_histoneacetyltransferaseandtranscriptionregulatoryprotein
192183___________ +1.01 +1.020.7240.4720.8341706717278174216.6080_ABCtransporter|besthomologofKillertoxinREsistant
19658____________ +1.24 +1.150.0200.0220.0701251015520143876.6552_
*196853___________ -3.40 -3.330.0000.0000.0007426121867223096.7002_hypotheticalprotein
*194041___________ -3.26 -3.200.0000.0010.0004882614975152796.7454_E2ubiquitin-conjugatingenzyme-peroxin
194601___________ -1.00 -1.040.4990.9550.2771283112787123976.7900_transcriptionfactorTFIIIC
*195356___________ +1.73 +1.930.0020.0080.0041625028065313756.8344_
197522___________ +1.39 +1.370.0010.0050.0031589222080217626.8774_conservedhypotheticalprotein
*195382___________ +1.30 +1.340.0080.0130.0252342130332314556.205__
*191175___________ +1.36 +1.260.0010.0030.0091800324500227016.815__
*192432___________ +1.76 +1.900.0010.0030.0041529126945290526.1395_transcriptionfactorthatbindstoCREmotif
191610___________ +1.31 +1.150.0040.0040.0311566620581180506.1936_
*196259___________ +1.56 +1.390.0020.0040.0081490623194206816.2458_ribosomalRNAProcessing
*19789____________ +1.65 +1.440.0010.0030.0071498324659215876.2990_
191116___________ +1.32 +1.080.0080.0060.1801269016760137636.3468_hypotheticalprotein
*191509___________ +5.26 +6.230.0000.0000.000251361323221566186.3960_
195592___________ +1.15 +1.080.0410.0210.3761258614516136326.4434_
*191060___________ +2.46 +2.370.0000.0000.0001873246090444536.4929_hypotheticalprotein
196173___________ +1.08 +1.010.4400.2280.8727911485537798106.5394_transcriptionfactor|interactswiththeSNF1proteinkinaseandTBPintwo-hybridandininvitrobindingstudies
193134___________ +1.09 +1.010.1110.0530.5551251213666126846.5871_hypotheticalprotein
*195117___________ +1.39 +1.680.0180.1510.0151451152018772441376.6335_
196687___________ +1.22 +1.110.0130.0110.0961251815274139306.6796_hypotheticalprotein
19353____________ -1.16 -1.030.0670.0350.4032956625562287026.7237_protease
195254___________ +1.18 +1.110.0110.0110.0691327315606147226.7688_hypotheticalprotein
*197234___________ +2.03 +2.300.0000.0010.0011757735615403506.8134_eighthlargestsubunitofRSC
*197405___________ +1.58 +1.620.0000.0010.0002287036184370526.8565_hypotheticalprotein
*197665___________ -1.41 -1.250.0020.0030.0133815626996305716.9013_conservedhypotheticalprotein
191327___________ +1.19 +1.120.0210.0200.0891252014894140346.489__
19579____________ +1.08 +1.060.7560.6260.6311306414138137916.1108_
*193156___________ +1.87 +1.580.0010.0020.0131454627140230186.1664_
195544___________ +1.26 +1.120.1640.0710.9241457218345162996.2202_
19643____________ +1.03 +1.010.6500.4550.6611230212662124446.2716_mayparticipateinchromosomesegregation
*193941___________ +1.10 +1.300.0050.0860.0044342347838564476.3228_CTPsynthase
192790___________ +1.10 +1.040.0910.0540.3261422615607147306.3719_
192352___________ +1.17 +1.130.0190.0240.0581289315115145996.4200_conservedhypotheticalprotein
192731___________ -1.03 +1.070.2710.4550.1772539824688272376.4687_
*19210____________ +1.05 +1.190.0110.1270.0102566126860304406.5163_conservedhypotheticalprotein
*19320____________ -1.68 +1.310.0030.0040.03290764540231185976.5638_shortchaindehydrogenase
193430___________ +1.05 -1.000.3860.1920.8911207212642120356.6095_hypotheticalprotein
19673____________ -1.02 +1.170.1720.7850.0842631025805308936.6566_NADPHdehydrogenase
196865___________ +1.23 +1.210.0070.0130.0181624319898195936.7014_killertoxininsensitiveprotein
192088___________ +1.25 +1.290.0030.0090.0091584119755204066.7467_subunitofDNApolymeraseepsilon

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194615___________ +1.37 +1.280.0020.0050.0081489120423190186.7914_conservedhypotheticalprotein
*195370___________ +1.22 +1.530.0030.0310.00473856902111133156.8359_conservedhypotheticalprotein
197542___________ +1.25 +1.230.0050.0150.0121795422449220376.8792_
*195056___________ +1.33 +1.260.0010.0030.0051823224181229916.17___
*195543___________ +1.22 +1.030.0110.0060.4866594480749680076.513__
198381___________ +1.09 +1.060.0900.0750.1941438015649152136.1126_ribosomalproteinS9B
*194697___________ +3.02 +2.430.0000.0010.002421381270691022736.1682_
*196474___________ +1.31 +1.210.0270.0200.1686456484444779856.2218_simtoglutaminerichproteinsimilartoglutenins
194196___________ +1.07 +1.120.0350.0440.0781259813436141166.2739_hypotheticalprotein
195567___________ +1.03 +1.020.5160.6970.3221685317385171846.3244_rRNAandtRNAprocessing
193083___________ +1.06 +1.070.1070.1070.1681216312937130376.3738_celldivisioncontrolprotein
*194421___________ +1.27 +1.560.0000.0050.0011443118391225206.4218_glucosidaseI
192745___________ +1.22 +1.250.0010.0060.0031485818089186306.4701_
6518_____________ +1.17 +1.220.0080.0200.0181413616601172096.5180_
193976___________ +1.11 +1.080.0440.0400.1261407715598151916.5651_
192910___________ +1.08 +1.050.0430.0430.1151919620678201736.6112_hypotheticalprotein
192768___________ +1.15 -1.020.2090.1020.6548630599016849606.6584_vacuolaralphamannosidase
191891___________ -1.01 -1.200.2700.8930.1342868252837982382546.7029_vacuolarasparticproteinaseprecursor
192073___________ +1.03 -1.110.2530.4610.1614384245098394326.7482_membranetransporter,antimicrobialresistance
194628___________ +1.20 +1.230.0020.0070.0071446417358177806.7927_conservedzincfingerprotein
*197292___________ +1.20 +1.240.0330.1130.034857761026211066986.8373_endocytosisandmembranegrowthandpolarity
196824___________ +1.06 +1.030.1390.0700.5231428015081147176.8808_
Cachs4___________ +1.07 +1.130.0280.0800.034121311301913676Cachs4_
*194316___________ +1.35 +1.340.0010.0030.0032530834253338326.222__
*191658___________ +3.89 +3.860.0000.0000.000371601445071435096.834__conservedhypotheticalprotein
192621___________ +1.00 +1.080.3760.8430.1993312733182358816.1412_partoftheSm-corethatiscommontoallspliceosomalsnRNPs
*191923___________ +2.05 +2.060.0000.0010.0012718255795559566.1955_
*192163___________ +2.67 +2.680.0000.0000.0002480066282665576.2476_conservedhypotheticalprotein
191253___________ +1.11 +1.090.1440.0710.5531237413748134596.3005_
194273___________ +1.01 +1.140.3640.5080.2411982520085225356.3485_
*194243___________ +1.43 +1.350.0010.0020.0041933027719260996.3981_conservedhypotheticalprotein
*195510___________ +1.83 +2.050.0000.0010.0013049855675624136.4453_
*195845___________ -1.29 -1.140.0360.0240.1986187048125540886.4947_ribonucleotidereductase
196187___________ +1.04 -1.010.8980.8200.7319048094300900016.5408_hypotheticalprotein
*192259___________ -2.93 -2.830.0000.0000.0007458625471263586.5887_hypotheticalprotein
192010___________ +1.08 +1.130.0830.2360.0641511316392170096.6350_
*196701___________ +3.04 +3.880.0000.0010.0002122864547822676.6809_
194441___________ +1.12 +1.080.0870.0780.1763014333852326006.7254_requiredforS-phaseinitiationorcompletion
*195241___________ +2.73 +2.560.0000.0000.0013100884729793556.7702_
*197247___________ +2.39 +2.350.0000.0010.0012776966276653596.8149_
*197420___________ -1.20 -1.210.0030.0070.0117466462351617006.8580_RNApolymeraseIItranscriptionalregulationmediator
197680___________ -1.11 -1.160.0620.6260.0321325151193731142826.9027_
*192414___________ -2.82 -2.920.0000.0000.00014340650866491726.40___mitochondrialmembraneprotein
*191372___________ -3.16 -3.010.0000.0000.00016193751167537216.530__
193376___________ +1.21 +1.140.0170.0140.1141480017959169426.1152_hypotheticalprotein
193209___________ +1.05 +1.040.6990.7230.4921492915728154826.1699_hypotheticalprotein
*191802___________ +1.69 +1.950.0000.0010.0004424674590864216.2234_conservedhypotheticalprotein
193639___________ +1.10 +1.040.0690.0550.1861484816345154206.2754_3-methyladenineDNAglycosylase
194325___________ +1.32 +1.220.0050.0090.0211253816599153196.3261_conservedhypotheticalprotein
*19841____________ +1.32 +1.410.0010.0060.0023606847485509716.3753_CASPOfCandida
*194897___________ +1.14 +1.280.0010.0120.0014252248564543166.4233_phosphatidylinositoltransferprotein
*194662___________ +1.67 +1.830.0000.0020.0011757729277322286.4714_
194292___________ +1.26 +1.170.0060.0100.0231634820534191576.5194_integralmembraneprotein|syntaxin
196148___________ +1.05 +1.050.0820.0710.1811238513032129566.5665_
192897___________ -1.03 -1.050.1770.3120.1331534114896145886.6125_peroxisomal2,4-dienoyl-CoAreductaseandsorbitolutilizationprotein
194248___________ -1.13 -1.170.0140.0360.0242794624788238556.6597_
191878___________ -1.07 -1.060.1030.1700.1042714925332256566.7042_transcriptionmediator
192061___________ +1.10 +1.050.0600.0350.3041236813612129316.7494_hypotheticalprotein
*197016___________ +1.18 +1.170.0120.0260.0252333627546273946.7942_vacuolarendopolyphosphatase
*197305___________ -1.16 -1.080.0460.0280.2612976025666274396.8386_hypotheticalprotein
*196809___________ +2.12 +2.640.0000.0020.0011600733875422736.8822_PhosphoMUtase
Cahyr96__________ -1.01 +1.010.7280.5730.642120071187512086Cahyr96
193216___________ +1.32 +1.180.0060.0070.0421479119473174096.242__
193212___________ +1.23 +1.220.0020.0070.0071907823445232006.848__integralplasmamembraneprotein
*196014___________ +1.91 +1.850.0000.0010.0011767533737326596.1432_
192724___________ +1.03 +1.100.1720.3490.1202765928396303116.1970_
*194072___________ +1.36 +1.240.0010.0030.0091579621516195806.2491_
194062___________ +1.09 +1.030.0760.0390.4371328414415136416.3019_splicingfactor|bindstopolypyrimidinetractearlyduringspliceosomeassembly
*195188___________ +1.63 +1.410.0020.0040.0101491224280209906.3497_
*192934___________ +1.59 +1.940.0020.0070.0051550724611300156.3998_conservedhypotheticalprotein
195524___________ +1.22 +1.170.0020.0030.0181497618333175266.4466_hypotheticalprotein
*192473___________ +1.35 +1.380.0000.0020.0013865552068534306.4962_chromatinremodelingprotein
196199___________ +1.01 +1.080.5210.9600.2952768027909298306.5425_DNAhelicaseA
*194922___________ +1.21 +1.330.0050.0730.0052596031366345736.5902_hypotheticalprotein
*191993___________ +1.24 +1.360.0010.0070.0022091925958284596.6366_26Sproteasomeregulatoryparticle
*194110___________ +1.39 +1.280.0020.0030.0132796638851357246.6825_
*194451___________ +1.51 +1.770.0010.0060.0022147332412380126.7267_
196970___________ +1.14 +1.200.0070.0310.0111629418570195396.7716_hypotheticalprotein
197264___________ -1.01 -1.020.8560.8350.6521537215151150876.8164_multicatalyticendopeptidase
68595____________ +1.01 +1.060.3410.3080.3281346313558142096.8595_
*195994___________ +1.04 +1.140.0220.0280.0611464815257167546.9043_GTP-bindingproteinoftherasfamily
193209___________ +1.05 +1.050.8620.6930.7671957420564205376.58___
*194150___________ +1.53 +1.430.0020.0040.0071354620747194196.554__
*191812___________ +1.62 +1.460.0010.0020.0032175835258316766.1170_tyrosinephosphatase
192552___________ +1.07 +1.090.0610.0630.1261251513339136706.1718_
192282___________ +1.21 +1.140.0060.0070.0391570819013179256.2250_6-chlorohydroxyquinol-1,2-dioxygenase
191310___________ +1.26 +1.300.0100.0150.0311305416484169426.2770_
*192852___________ -1.20 -1.260.0010.0050.0013161726262251256.3278_mitochondrialribosomesmallsubunitcomponent
193463___________ +1.11 +1.080.0170.0150.1001236313762133136.3767_
*191839___________ +1.37 +1.240.0010.0010.0054056055728503326.4247_alphasubunitofRNApolymeraseI
*193341___________ -1.70 -1.960.0010.0030.0022468741449911262466.4732_arginyl-tRNAsynthetase
*194802___________ +1.76 +1.690.0000.0010.0011970234647332516.5208_
*196134___________ -1.13 -1.110.0360.0440.0843168828161284316.5680_conservedhypotheticalprotein
*195840___________ +1.41 +1.460.0000.0020.0011956027636284766.6138_conservedhypotheticalprotein
194234___________ +1.06 +1.040.1480.1850.1591622217206168606.6611_sharesterminatorwithTHR4
*191865___________ -1.51 -1.860.0000.0010.00111005672790590836.7055_aldehydedehydrogenase
193813___________ +1.02 -1.100.2070.1790.2664413044884400486.7509_
*197028___________ +3.54 +3.580.0020.0050.005521201844511867566.7954_hypotheticalprotein
*197317___________ +1.56 +1.550.0240.1300.0212094432587324256.8399_
196796___________ +1.15 +1.090.0200.0170.1081766720405193086.8835_sugar-nucleotidehydrolase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
Cayir7___________ +1.00 -1.020.7900.5380.872115461157611363Cayir7_
*192906___________ +1.13 +1.100.0090.0130.0312848832322312966.259__
*195069___________ +2.56 +1.920.0000.0010.0011444036940276606.865__conservedhypotheticalprotein
*193554___________ +4.43 +3.710.0000.0000.0001547668583573696.1447_
191499___________ +1.18 +1.170.0070.0090.0351295815248151236.1986_
19102____________ +1.09 +1.080.0940.0910.1651673218272179946.2505_hypotheticalprotein
*191693___________ +2.27 +1.940.0000.0010.0012062146820399706.3035_
194707___________ +1.30 +1.220.0070.0100.0281396418192169986.3511_
19697____________ +1.42 +1.230.0020.0030.0091612122950197866.4011_conservedhypotheticalprotein
*193184___________ -1.16 -1.170.0090.0220.0204916042521419506.4481_similartosyntaxinandinvolvedinERtoGolgitransport
192460___________ +1.30 +1.160.0080.0080.0601334217341155176.4975_
*196287___________ -2.48 -2.560.0000.0000.0002598101048951015166.5437_aspartateaminotransferase
*1924_____________ +1.99 +2.100.0000.0000.0001811136127380246.5918_putativetransporterorflippasetransmembraneprotein
*191416___________ -3.33 -3.120.0000.0000.00021176063583679086.6385_cytochrome-coxidaseassemblyprotein
194095___________ +1.22 +1.250.0080.0120.0281382316828172186.6841_hypotheticalprotein
*19897____________ -1.25 -1.230.0010.0020.0023163225344257746.7280_conservedhypotheticalprotein|coiledcoils
196982___________ +1.09 +1.090.0300.0240.1371353514703147296.7728_weaksimilaritytocarbamylphosphatesynthetase
197278___________ +1.21 +1.210.0090.0150.0281403617006169806.8178_polpolyprotein,reversetranscriptase
*197448___________ +2.06 +2.400.0000.0010.0012776157293665006.8608_seventhstepinlysinebiosynthesispathway|saccharopinedehydrogenase(NADP+,L-glutamateforming)
*195982___________ -1.39 -1.650.0160.0520.02313283295722803916.9055_ribosomalproteinL18A(rp28A)
682______________ +1.20 +1.180.0040.0070.0211242614887146286.82___
*192014___________ +2.20 +1.900.0010.0030.0041754738540332716.573__
19332____________ +1.22 +1.130.0040.0060.0271182414421133186.1189_
*194257___________ +1.77 +1.710.0020.0040.0131368424223234446.1731_
193761___________ +1.40 +1.250.0030.0050.0131298518199161836.2267_
193449___________ +1.21 +1.130.0180.0200.0701506418206169496.2791_highlyconservedhypotheticalprotein
*194913___________ +1.48 +1.260.0010.0010.0041763626101223036.3292_conservedhypotheticalprotein
195097___________ +1.18 +1.130.0090.0120.0401308415381147696.3783_
*192214___________ -2.34 -2.290.0000.0010.0014720220152205756.4259_mitochondrialribosomalprotein
192112___________ -1.06 -1.130.0200.2160.0152619424771232496.4749_U5smallnuclearribonucleoprotein(snRNA)particleprotein
194816___________ -1.25 -1.310.0030.0120.0062106016871160646.5222_conservedhypotheticalprotein
*19583____________ -1.28 -1.280.0020.0110.0052962223213232306.5697_tryptophan2,3-dioxygenase
195827___________ +1.05 +1.020.1570.1060.3261257813233128376.6151_spindlebodycomponentrequiredforcellcyclearrestinresponsetolossofmicrotubulefunction
195793___________ +1.05 -1.030.5810.3400.8172484025993240016.6627_26Sproteasomeregulatorysubunit
19498____________ -1.40 -1.430.0010.0020.0022414017279169346.7073_mitochondrialS4ribosomalprotein
193829___________ +1.10 +1.030.1800.0970.4961492116469153696.7524_pHregulatedGPI-anchoredmembraneproteinthatisrequiredformorphogenesis
*197042___________ +1.12 +1.110.0220.0170.1251504216871166536.7968_hypotheticalprotein
197330___________ +1.05 +1.040.1220.0730.3611331814039138956.8411_transcriptionalregulator
196784___________ +1.06 +1.060.1520.0870.4161363214505144486.8847_conservedhypotheticalprotein
42093____________ +1.02 -1.010.7170.4520.8921377914102136614.2093_
*19223____________ +1.43 +1.420.0020.0050.0081399820055198936.276__
*191683___________ +1.24 +1.070.0040.0040.0702499030908267236.890__
*192658___________ +1.51 +1.350.0000.0010.0042209133309298456.1463_mitochondrialimportinnermembranetranslocasesubunit
191677___________ +1.19 +1.140.0080.0110.0311310615586149166.1999_hypotheticalprotein
*193360___________ +1.89 +1.900.0030.0050.0121510028564286646.2525_
194884___________ +1.04 +1.010.1940.0910.7121212412601122046.3050_requiredforgluconate-H+symport
19641____________ +1.18 +1.120.0140.0120.0891283815201143326.3528_conservedhypotheticalprotein
195371___________ +1.15 +1.080.0190.0140.1371405816172151876.4025_hypotheticalprotein
*192834___________ +1.25 +1.350.0010.0040.0012862135645385386.4495_histonedeacetylase
193471___________ +1.32 +1.290.0010.0030.0031548620482199146.4988_
194682___________ -1.03 -1.040.5220.6830.3311398813644134516.5454_quinatepermease
*19200____________ +1.36 +1.580.0000.0030.0003043041236480866.5932_roleintranscriptionalregulation
191430___________ +1.08 +1.020.1680.0760.7441285413889130596.6399_hypotheticalprotein
*194082___________ -4.55 -3.940.0000.0000.00021329246895541026.6853_
19881____________ -1.00 +1.080.1410.6420.0722315423103249336.7296_transmembraneprotein
*196994___________ +1.17 +1.170.0080.0260.0132314727101271156.7740_branchedchainaminoacidaminotransferase
19942____________ +1.02 -1.000.4170.2110.9211235612548123126.8191_beta-glucansynthase
*195384___________ +1.11 +1.160.0400.0460.0931469416327170776.8621_
195968___________ +1.16 +1.150.0190.0160.1211413216416163116.9068_
*193550___________ +1.28 +1.310.0020.0060.0061601720467209546.103__
19543____________ +1.10 +1.090.0510.0610.0992079822802226186.596__
19749____________ +1.33 +1.200.0050.0060.0341644621924197636.1208_
*191183___________ -1.19 -1.160.0440.0490.0993752431631323026.1750_
19474____________ +1.28 +1.220.0020.0070.0071660321184203136.2284_conservedhypotheticalprotein|S.cerevisiaeorthologisessential
194353___________ +1.11 +1.110.0180.0280.0441454316137161946.2809_Ubl(ubiquitin-likeprotein)-specificprotease
*193656___________ -2.21 -2.360.0000.0010.0004489220316189906.3305_cytochromeoxidaseassemblyfactor
195718___________ +1.15 +1.070.0160.0120.1451632818804174376.3801_Vps18protein
*192611___________ +1.35 +1.270.0020.0040.0092523434037321716.4274_involvedinreplication
*192098___________ +1.78 +1.570.0010.0010.0042672547522420076.4764_
194136___________ +1.16 +1.150.0080.0130.0241351915717154866.5241_
192978___________ -1.76 -1.850.0010.0040.0042895716492156626.5711_hypotheticalprotein
*192483___________ +1.37 +1.220.0020.0020.0453921853541478076.6164_putativetelomerebindingprotein
195808___________ +1.09 +1.050.4130.3280.4171592617379167766.6642_RapidResponsetoGlucose
19484____________ +1.03 -1.010.3660.1770.9921508015476148896.7087_mitochondrialribosomallargesubunitprotein
193845___________ +1.04 -1.010.4820.2520.9661765118420174556.7540_zincfingerprotein
195027___________ +1.35 +1.300.5820.8960.3461802224331234436.7981_
197344___________ +1.11 +1.050.1050.0630.3361309214595136856.8425_ploidy-related
*196771___________ +1.24 +1.210.0120.0290.0221230441524461490656.8860_polyubiquitininvolvedinstressresponsesystem
42459____________ +1.08 +1.070.0930.0570.3171212013098129504.2459_
191932___________ +1.33 +1.290.0020.0070.0061284017030166146.292__
*191294___________ +1.92 +1.890.0000.0020.0011981038079374306.913__
193626___________ +1.38 +1.270.0030.0050.0141346418533170966.1479_similartoglucosamine6-phosphatesynthetaseandasparaginesynthase
*191743___________ +2.16 +1.860.0010.0020.0031515432682281756.2015_acetyl-coenzymeAsynthetase
194769___________ +1.28 +1.200.0020.0030.0091308816719156616.2539_necessaryforsynthesisofmannose-(inositol-P)2-ceramide(M(IP)2C)|inositolphosphotransferase1|mannosyldiphosphorylinositolceramidesynthase
193789___________ -1.02 -1.060.1580.4320.0962187321548207256.3063_
19866____________ +1.32 +1.290.0010.0040.0041499919856192826.3549_
*195817___________ +1.27 +1.140.0310.0210.1871459718521166346.4042_SNAREproteininvolvedintargetingandfusionofERtoGolgitransportvesicles
*195641___________ -4.02 -3.720.0000.0000.00030270375232814486.4510_ornithineaminotransferase
194509___________ +1.19 +1.170.0400.0660.0631280215240149576.5002_hypotheticalprotein
*193737___________ +1.28 +1.210.0040.0090.0153985851067482706.5467_hypotheticalmembraneprotein
*195148___________ +1.44 +1.420.0050.0110.0171401420110198576.5949_
*191553___________ +1.55 +1.550.0010.0020.0024747273479733846.6412_
196718___________ +1.09 +1.040.0580.0440.1862848731140297036.6867_conservedhypotheticalprotein
*196923___________ +1.35 +1.280.0020.0060.0052136628785272696.7309_transcriptioninitiationfactorTFIID
193016___________ +1.17 +1.110.0110.0140.0462059424028229206.7753_conservedhypotheticalprotein
19956____________ +1.18 +1.100.0080.0090.0471262014953138376.8206_
195399___________ +1.02 -1.010.9510.7720.9841568515961155226.8634_
195954___________ +1.14 +1.060.0250.0170.1911352815413143146.9082_
194169___________ +1.34 +1.230.0060.0120.0171334217818164066.123__hypotheticalprotein
191006___________ +1.40 +1.190.0060.0080.0341340418819160146.614__hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
19857____________ +1.25 +1.130.0050.0050.0491447618078163016.1228_
*194216___________ -4.73 -3.570.0000.0000.00011659724657326356.1771_
193936___________ +1.23 +1.170.0060.0090.0271217614934142976.2299_conservedhypotheticalprotein
194424___________ +1.14 +1.120.0320.0310.1051301214878146036.2829_
195042___________ +1.18 +1.120.0130.0120.0811323415551148056.3319_hypotheticalprotein
192647___________ +1.25 +1.150.0110.0130.0471283715989147406.3816_
*193542___________ +1.53 +1.580.0000.0020.0022599839666410776.4288_roleinphospholipidtranslocationacrosstheplasmamembrane.|membraneglycoprotein
*195621___________ +1.53 +1.500.0000.0010.0011963729985295246.4780_conservedhypotheticalprotein
193356___________ +1.09 +1.130.0130.0250.0281287814084146066.5258_
*191258___________ +2.71 +3.580.0000.0040.0011595143279571346.5725_hypotheticalprotein
192499___________ -1.05 -1.080.0950.1700.0941916218322177336.6180_peptidyl-prolylcis-transisomerase
*192960___________ -1.18 -1.140.0110.0090.1086259252875548206.6656_phenylalanine-tRNAligasebetachain
67104____________ +1.07 +1.020.0900.0410.5911201012892122306.7104_
196570___________ +1.13 +1.070.0280.0170.2361240913995132436.7558_purinenucleosidepermease
195014___________ +1.10 +1.050.1770.1140.3661261013836132016.7995_conservedhypotheticalprotein
197115___________ -1.22 -1.080.3350.2740.3607174758819666386.8438_GTPaseactivatingprotein(GAP)forRHO
*196757___________ +1.24 +1.300.0050.0580.0064544756535591316.8874_similartomammalianaldo/ketoreductases
42736f--3________ -1.01 -1.030.8220.8770.5901185211764115504.2736f
193523___________ +1.26 +1.240.0030.0050.0151335016801164926.309__
191496___________ +1.19 +1.140.0080.0110.0371321815708150456.933__hypotheticalprotein
193532___________ -1.02 +1.050.2230.9810.1081767317318186256.1498_mitochondrialribosomalprotein
193522___________ +1.22 +1.100.0150.0100.1711275215493140166.2035_reversetranscriptase
193781___________ +1.15 +1.170.0070.0140.0191295014930151036.2553_
191220___________ -1.06 -1.120.1070.1480.1232974528149266526.3078_cytoskeletalbindingandregulatoryprotein
*192277___________ +1.27 +1.210.0020.0030.0102860136254345336.3564_cAMP-dependentproteinkinasecatalyticsubunit
193921___________ -1.03 +1.040.9330.7770.8582914228395302386.4055_dihydrofolatereductase
196217___________ +1.09 +1.010.3560.1710.9942234824265224696.4530_
*194204___________ -1.68 -1.790.0010.0040.0033557021196199126.5017_mitochondrialribosomalproteinofsmallsubunit
*192693___________ +1.74 +2.510.0000.0010.0001267662208843176066.5481_nitrogencataboliterepressionregulatorandpriongenerator
*195136___________ +1.39 +1.340.0020.0050.0081677523344224806.5962_conservedhypotheticalprotein
191567___________ +1.09 +1.060.0190.0140.1371553016945164776.6425_
196731___________ -1.06 -1.060.1100.1190.1561529114489143676.6880_hypotheticalprotein
*196937___________ +2.61 +3.410.0000.0000.000721911887762463806.7323_peptidetransporter
193030___________ +1.03 +1.020.1430.0680.5951455614958148766.7767_conservedhypotheticalprotein
19970____________ -1.06 -1.090.0800.1110.1051568914848143916.8219_conservedhypotheticalprotein
*195413___________ +1.37 +1.480.0040.0110.0091604821913237706.8649_pre-mRNAsplicingfactor
195940___________ +1.04 -1.000.4950.4040.4531476015358146966.9098_
19124____________ +1.14 +1.190.0160.0300.0331247014186148586.137__proteasesubstraterecruitmentfactor
191024___________ +1.20 +1.190.0120.0160.0401245414897148736.645__hypotheticalprotein
61244____________ +1.35 +1.280.0020.0050.0071313717745168806.1244_
193365___________ +1.35 +1.220.5290.2920.8651896225635231066.1786_d-aminoacidoxidase
191039___________ +1.15 +1.100.0280.0310.0811245614325136706.2318_geranylgeranyltransferasetypeIIalphasubunit
*194961___________ +2.03 +1.690.0000.0000.0003406369311574596.2844_proteininvolvedinpre-tRNAsplicing
*194889___________ +1.23 +1.220.0040.0100.0112207427139268496.3333_histidinolandsodiumpermease|memberofmajorfacilitatorsuperfamilymultidrug-resistanceproteinsubfamily1
194872___________ +1.11 +1.060.0620.0420.2301258213969132886.3831_hypotheticalprotein
194483___________ +1.13 +1.070.0420.0410.1141538317329165066.4304_conservedhypotheticalprotein
192686___________ -1.00 +1.030.5670.4340.5311554015534159766.4797_
*196544___________ +1.79 +1.660.0020.0050.0081560827992258966.5270_
191662___________ -1.12 -1.180.0130.0400.0211692015051143886.5737_mitochondrialribosomalsmallsubunitprotein
195760___________ +1.04 +1.040.3270.1790.6181452915042151466.6197_
*192947___________ -3.28 -4.250.0000.0010.0009802129912230466.6669_stationaryphaseprotein
*191457___________ +1.36 +1.250.0400.0790.0552535034596316656.7116_componentofRNApolymerasetranscriptionfactorTFIIH
196584___________ +1.03 -1.030.4930.3580.5142306923681222906.7572_translationinitiationfactoreIF3subunit
*195000___________ +2.36 +2.310.0000.0010.0022487658701575496.8010_
197101___________ -1.01 -1.060.2260.5850.1262692026532253856.8452_involvedincontrollingtelomerelength
*196744___________ -1.15 -1.350.0250.1210.0234235136888313036.8887_Mg-dependentDNaseinvolvedinDNAreplication,recombination,andrepair
42832____________ +1.07 +1.030.2030.1010.6071223813115126044.2832_
192725___________ +1.21 +1.200.0030.0070.0091274215408152306.325__hypotheticalprotein
19188____________ +1.22 +1.180.0040.0080.0121382916849163686.951__
193621___________ +1.34 +1.190.0030.0040.0201314417588155806.1513_putativecellwallprotein
193592___________ +1.22 +1.110.0160.0130.1141866722710207696.2050_DnaJ-likeprotein
19104____________ +1.31 +1.250.0030.0050.0151277216687159906.2572_
194560___________ +1.21 +1.090.0190.0120.1911382416777150826.3093_
*192208___________ -1.05 -1.160.0100.0980.0103142629883271716.3579_
194666___________ -1.07 -1.080.0620.1250.0682399622364223006.4069_
194376___________ +1.26 +1.230.0020.0050.0061445118239177986.4541_conservedhypotheticalprotein
*193325___________ +3.12 +3.060.0000.0000.000709332216532169626.5029_self-glucosylatinginitiatorofglycogensynthesis
196306___________ +1.07 +1.020.2080.1030.6151736218567177756.5499_mitochondrialaldehydedehydrogenase
*192037___________ +1.98 +1.980.0000.0010.0012201243489435066.5976_hypotheticalprotein
*191633___________ +1.54 +1.820.0000.0030.0012483638278452666.6439_U3snoRNPprotein
195655___________ +1.30 +1.200.0060.0110.0181473619193176186.6896_dioxygenasealphasubunit
*196953___________ +1.16 +1.120.0230.0290.0642067024026231796.7339_conservedhypotheticalprotein
193045___________ +1.07 +1.030.3020.1950.4562382425497245546.7782_mitochondrialaldehydedehydrogenase
193233___________ +1.12 +1.100.0120.0180.0381278414316141176.8233_involvedinprotein-vacuoletargeting
*195428___________ +1.19 +1.270.0020.0060.0042054324489261226.8664_manganese-traffickingprotein
195926___________ -1.11 -1.040.0840.0460.3671879116984181296.9111_mitochondrialornithinetransport
*195704___________ +1.13 +1.150.0070.0260.0132405127141275536.151__
19154____________ +1.26 +1.150.0100.0130.0421368217260157756.659__conservedhypotheticalprotein
191863___________ +1.30 +1.200.0020.0040.0081358117612163306.1263_hypotheticalprotein
*193394___________ +1.23 +1.280.0010.0040.0022199527132282626.1807_hypotheticalprotein
*191646___________ +1.55 +1.490.0040.0080.0131869629053278576.2336_
*19926____________ +1.91 +1.990.0000.0010.0011724432988343826.2862_exonuclease
*192654___________ +1.54 +1.530.0010.0030.0011729426547263756.3349_
*19835____________ +1.33 +1.210.0010.0030.0062117528191255496.3846_conservedhypotheticalprotein
*194471___________ +1.88 +2.070.0000.0020.0011767533194365246.4316_containsanFHA(forkhead-associated)domain
*19285____________ +1.65 +1.750.0010.0030.0021195781976922093456.4814_conservedhypotheticalprotein
*193006___________ +1.22 +1.400.0010.0100.0024698857133656646.5283_Golgi-localizedprotein,gamma-adaptin
*193579___________ -2.97 -3.540.0000.0000.0008591628922242556.5750_ATPsynthaseF0sectorsubunit4
*196601___________ +2.60 +2.920.0000.0010.0012445063658715126.6213_hypotheticalprotein
*194535___________ +2.00 +1.960.0000.0010.0012129342660418336.6681_transcriptionalregulatorofpeptidetransport
196867___________ +1.01 -1.020.9600.9900.8051485714970146196.7131_similartoLIMhomeoboxandsteroid-bindingproteins
196040___________ +1.23 +1.160.0110.0110.0611421617509164406.7584_involvedinlateendosometovacuoletransport
194985___________ -1.03 -1.040.4310.6040.2711536814851147286.8023_
*197088___________ +1.15 +1.190.0080.0500.0102307526430275276.8465_translationinitiationprotein
*197552___________ +1.82 +2.410.0000.0020.0012550346376614566.8900_conservedhypotheticalprotein
42909____________ +1.09 +1.050.0690.0670.1461236613510129934.2909_
191957___________ +1.15 +1.120.0090.0120.0351452716755162656.343__
*1938882__________ +1.57 +1.330.0010.0010.0041486223380197816.968__NA
192822___________ +1.45 +1.330.0010.0030.0041433220773191006.1530_
*193642___________ +3.75 +4.180.0000.0000.000297981118261246906.2071_beta-glucosidase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*19868____________ +1.45 +1.190.0010.0010.0122265232939268626.2587_
194278___________ +1.30 +1.180.0020.0030.0251509419668177486.3109_
192605___________ +1.05 +1.090.5770.5530.4394551047659493836.3594_serine/threonineproteinkinaseinvolvedinregulationofactincytoskeletonorganization
*191955___________ +1.41 +1.450.0020.0050.0051642223119238646.4084_involvedinRASlocalizationandpalmitoylation
*1950_____________ +1.99 +2.070.0000.0000.0002139242675443456.4556_F-boxubiquitinligase
65043____________ +1.18 +1.130.0050.0050.0601262214902142616.5043_
*196321___________ -1.32 -1.250.0200.0310.0467915459923634946.5514_hypotheticalprotein
*192049___________ +1.32 +1.320.0000.0020.0011834924196242806.5988_hypotheticalprotein
*193449___________ -1.67 -1.290.0010.0010.0055481232806424396.6456_
195669___________ +1.01 +1.010.6300.9490.3822365323889238106.6909_ER25kDatransmembraneprotein
194855___________ +1.07 +1.060.0370.0540.0701495715990159116.7356_similartoXenopusG10maternaltranscript|possibleroleinbudsiteselection
193057___________ -1.16 -1.090.3270.1560.8921795715499164736.7794_involvedinmitochondrialDNAmaintainance
*193245___________ +1.22 +1.330.0160.0300.0331426417341189726.8246_
195440___________ -1.18 -1.070.2780.1590.5317459263046695326.8676_26Sproteasomesubunit
*195912___________ +1.36 +1.540.0010.0040.0041613021971248996.9124_
*196309___________ +1.50 +1.360.0040.0060.0191639424671222846.20___
*192160___________ +1.20 +1.040.0200.0120.2522307827584238966.681__
*191927___________ +1.27 +1.210.0040.0140.0091822623150220186.1279_
1934_____________ +1.33 +1.260.0030.0050.0121462819471183976.1824_
192541___________ +1.33 +1.400.0030.0080.0081457819360203416.2350_conservedhypotheticalprotein
193697___________ +1.06 +1.040.2090.1180.4811198412680124576.2880_conservedhypotheticalprotein
196502___________ +1.13 +1.090.0460.0370.1531281514476139516.3367_
192387___________ +1.11 +1.090.0580.0540.1431193413236129606.3860_
*193399___________ +1.26 +1.340.0100.0220.0232170027450290206.4333_
*19602____________ +1.42 +1.430.0030.0050.0103445948996491786.4829_
*191364___________ +1.76 +1.590.0000.0010.0012391241972380246.5296_conservedhypotheticalprotein
*193564___________ +1.26 +1.270.0120.0180.0342499731372316906.5765_RNApolymeraseIII(C)subunit
196114___________ -1.01 -1.440.0770.7860.0371662101637661152406.6227_hypotheticalprotein
*194548___________ +1.15 +1.020.0450.0210.5482225925591227906.6694_
*196881___________ +2.90 +2.240.0000.0000.000665641931301488876.7145_cleavageandpolyadenylationspecificityfactor
*196054___________ +1.34 +1.200.0110.0180.0312887238649345396.7598_similartoBUL1,involvedinprotienubiqutination
197140___________ +1.03 -1.140.0920.4820.0517424476432651266.8040_catecholo-methyltransferase
197074___________ +1.05 -1.030.2860.1320.9131873719589182166.8479_subunitofSAGAhistoneacetyltransferasecomplex
197566___________ +1.02 -1.080.2800.2200.3453883439796358346.8914_high-affinityglutaminepermease
p18b=p18_________ +1.06 +1.020.1040.0450.740123731308212598p18b=p1
*191224___________ +1.67 +1.290.0040.0050.0422380539843306176.361__
*19475____________ +1.32 +1.460.0010.0090.0032802536941410056.987__
195530___________ +1.05 +1.020.3030.1450.8202868630106292096.1545_
195751___________ +1.32 +1.190.0210.0130.2031598021107189436.2090_involvedinresponsetounfoldedproteins
*19130____________ +1.71 +1.840.0030.0070.0071413424147260416.2603_
*191704___________ -1.03 -1.150.0490.3900.0292750826780238896.3124_
*192791___________ +1.71 +1.650.0000.0010.0014648879582766856.3609_
*192599___________ -4.92 -5.750.0000.0000.00016355233263284286.4099_mitochondrialcarnitinetransporter
195692___________ -1.09 -1.200.1180.3310.0805408749589452096.4570_hypotheticalprotein
*195864___________ +1.42 +1.530.0020.0070.0054340661840664346.5056_uridinekinase
*196339___________ +1.45 +1.390.0010.0020.0031983628859275096.5532_hypotheticalprotein
196455___________ +1.05 +1.050.0650.0420.2592818029701295336.6004_conservedhypotheticalprotein
*193437___________ +1.81 +1.920.0000.0020.0011828833062351006.6468_hypotheticalprotein
193123___________ +1.02 +1.010.6880.9780.4328636687818875436.6922_26Sproteasomeregulatorysubunit
*194839___________ -1.12 -1.480.0010.0420.0016669159425451126.7372_conservedhypotheticalprotein
*196448___________ +1.34 +1.180.0040.0040.0342481833244293616.7806_hypotheticalprotein
*193260___________ +2.29 +2.430.0000.0010.0011787240887433456.8260_phosphopantothenoylcysteinedecarboxylase
*195454___________ +8.78 +8.800.0000.0000.000206381812071815236.8688_
195897___________ +1.17 +1.110.0050.0040.0731475817248164256.9139_
*194282___________ +2.94 +3.150.0000.0010.0012248766180708786.55___
*19768____________ +2.56 +2.370.0000.0000.0002110754005501146.698__
195547___________ +1.24 +1.110.0070.0080.0481316816323146606.1296_conservedhypotheticalprotein
*194632___________ +1.25 +1.200.0200.0270.0547095488338854846.1842_ribosomalproteinL20
*194641___________ +2.02 +2.110.0010.0030.0031582531921333406.2367_myristoyl-CoA:proteinN-myristoyltransferase
*191275___________ +2.37 +2.730.0020.0060.0051343831860367386.2898_activatoroftranscriptionofnitrogen-regulatedgenes
195056___________ +1.20 +1.150.0130.0150.0541294115510149136.3381_
*193689___________ +2.15 +2.310.0000.0000.000532581146721229586.3877_
*192195___________ +1.70 +1.680.0010.0030.0041593927038267376.4346_hypotheticalprotein
*191717___________ +1.18 +1.170.0040.0080.0132166025450252356.4843_conservedhypotheticalprotein
*193712___________ +4.10 +4.670.0000.0000.000484281987712260196.5310_hypotheticalprotein
*196350___________ +4.46 +3.620.0000.0010.0011387061803502696.5779_hypotheticalprotein
*196099___________ +1.36 +1.400.0000.0010.0005648876921790896.6243_
*19819____________ -1.97 -1.950.0000.0010.00115624579450799596.6710_mitochondrialacylcarrierprotein
*196896___________ +2.30 +2.600.0010.0030.0021786841096464306.7160_hypotheticalprotein
196066___________ -1.04 -1.130.0410.1850.0332424023347214306.7610_conservedhypotheticalprotein
197156___________ -1.16 -1.110.0100.0130.0392606122400234626.8056_long-chainfattyacidCoAligase
197061___________ +1.22 +1.150.0570.0730.0971977924161226576.8492_similartopantothenatekinase
*197580___________ +1.40 +1.560.0010.0040.0013553049714555696.8928_hypotheticalprotein
act1_____________ -1.00 +1.020.5950.4010.649118861187912145act1___
*19614____________ +1.23 +1.190.0150.0460.0231260515536149996.379__hypotheticalprotein
*19769____________ +1.67 +1.610.0000.0010.0011658227761266416.1010_
*1986_____________ +4.77 +5.740.0000.0000.000541532583443109776.1559_glutathioneperoxidase
*191480___________ -3.78 -3.440.0000.0000.00025146266600730416.2104_succinatedehydrogenase
194161___________ +1.15 +1.140.0100.0150.0331884121606215406.2625_conservedhypotheticalprotein
191655___________ -1.22 -1.240.0220.0340.0512244318406181716.3140_fatty-acylcoenzymeAoxidase
*192444___________ +2.71 +2.710.0000.0000.0002812176270762216.3622_involvedinchitinsynthesis
*19781____________ +7.97 +10.140.0000.0000.000132911059601348316.4115_ureaactivetransportprotein
*192808___________ -2.05 -2.390.0000.0010.0019835248003411886.4585_zincfingertranscriptionfactor
*195601___________ +1.13 +1.100.0380.0690.0573615240752397886.5071_conservedhypotheticalprotein
*192304___________ +1.95 +2.170.0000.0000.00050418981471096346.5546_golgivesicleprotein
*19727____________ +2.82 +3.020.0000.0010.0011687447607510266.6016_hypotheticalprotein
193671___________ +1.40 +1.230.0030.0060.0161357218934166956.6482_hypotheticalprotein
193109___________ +1.16 +1.100.0230.0150.1881429316560156946.6936_hypotheticalprotein
194825___________ -1.07 -1.070.0830.1630.0803146529480294306.7386_formationofmitochondrialcomplexes|assemblyfactorofATPsynthaseinheatstress|FormationofMitochondrialCytochromes
196434___________ -1.13 -1.010.6270.3730.8583824933943380216.7821_
193273___________ -1.06 -1.080.1440.1750.1602077519639192896.8273_piecemealmicroautophagyofthenucleus
195469___________ +1.14 +1.080.0220.0250.0731832920842197716.8706_
195884___________ +1.04 -1.010.1830.0800.9721299013544129236.9154_
193742___________ -1.06 -1.130.1550.3230.1111398113211123996.81___
193193___________ +1.46 +1.310.0040.0070.0151399420484183606.714__
*1979_____________ +3.55 +4.470.0000.0020.00123792845191063406.1310_cellsurfaceagglutinin
*191526___________ +3.33 +2.560.0000.0000.000523351745131339696.1859_componentofSWI/SNFglobaltranscriptionactivatorcomplex
*192018___________ +1.66 +1.850.0010.0030.0021667427758307896.2381_DnaJhomolog
*19173____________ +2.64 +2.130.0000.0000.00040064105944853596.2910_
*191519___________ +1.37 +1.380.0050.0100.0171465220108202866.3395_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*191338___________ +1.24 +1.020.0160.0090.3553705045982377646.3891_conservedhypotheticalprotein
*193498___________ +1.30 +1.240.0030.0070.0071719122275212766.4358_
195785___________ -1.18 -1.350.0030.0170.0061855815722137376.4857_hypotheticalprotein
65323____________ +1.27 +1.240.0050.0100.0131413717970175796.5323_
191004___________ +1.19 +1.130.0210.0230.0751717420437193266.5793_hypotheticalprotein
*196083___________ +1.45 +1.290.0000.0010.0031809926236232726.6258_hypotheticalprotein
*19512____________ +2.14 +2.770.0020.0070.0061395529925386796.6724_
*196909___________ +1.24 +1.270.0040.0070.0151960424279248666.7173_mediatorsubunitofRNApolymeraseII
*196536___________ +2.17 +1.900.0000.0000.0012754359765522576.7624_RASGTPase-activating-like
197167___________ +1.04 +1.060.2150.1620.3201348013997142306.8068_
*197049___________ +3.47 +2.890.0000.0000.0002500786870723686.8504_cytochromeb5
*197595___________ +1.29 +1.270.0010.0030.0032308629853293016.8943_hypotheticalprotein
*19522____________ +1.38 +1.430.0010.0050.0041871225763266806.396__
*194263___________ +1.61 +1.470.0010.0020.0022037732726298876.1032_hypotheticalprotein
191139___________ +1.33 +1.200.0040.0070.0191424718910170826.1574_
192968___________ +1.12 +1.070.0580.0360.2632263825304241416.2121_
*19719____________ +1.85 +2.010.0000.0000.0004695386762944226.2640_
*196029___________ +1.67 +1.510.0010.0020.0031682728107254496.3157_suppressoroftor2
*19759____________ +1.46 +1.300.0000.0000.00273156106699950856.3638_coatomergamma;non-clathrincoatproteininvolvedintransportbetweenERandGolgi
*195559___________ +1.48 +1.570.0010.0030.0021465421634229516.4129_
*194297___________ +1.67 +1.580.0000.0010.0022220937182351556.4603_
*191229___________ +3.01 +3.170.0000.0000.0002617078819829596.5087_specificexportinforSrp1p
*192673___________ +1.80 +1.720.0010.0020.0021789532211308556.5561_hypotheticalprotein
196269___________ +1.10 +1.100.1020.0590.3511295614292142186.6029_
*19426____________ +1.46 +1.530.0000.0020.0013533051725540086.6495_
*193093___________ +1.99 +2.080.0000.0010.0012771455147577366.6950_
*193990___________ +2.03 +1.870.0000.0010.0012596052615485976.7403_RNApolymeraseIIIsubunitC17
*196417___________ +1.71 +1.770.0010.0030.0025408492264959146.7837_conservedproteinpossiblyinvolvedinribosomebiogenesis
193287___________ +1.05 +1.060.2550.3520.1943682838556391206.8287_involvedinbudsiteselection
197472___________ +1.09 +1.110.0180.0310.0401486116168165126.8722_
*194874___________ +1.50 +1.470.0020.0050.0091708125669251916.112__
1964_____________ +1.30 +1.180.0030.0050.0131339817462157536.735__questionable(repetitivesequence)orf,Nterminusconsistsof~150Nresidues
191823___________ +1.42 +1.240.0010.0030.0091343819046166206.1325_
193489___________ +1.25 +1.140.0070.0100.0291378617243157446.1876_chorismatesynthase
*192238___________ +1.43 +1.430.0040.0080.0161316418852188896.2394_GDP/GTPexchangefactor
193384___________ +1.17 +1.120.0100.0130.0461294215182144566.2930_
*195196___________ +1.19 +1.060.0130.0110.1162638031297279716.3412_peptidylprolylcis/transisomerase
*195213___________ +1.54 +1.450.0030.0060.0091463622537212506.3904_pre-mRNAcleavageandpolyadenylationfactorIcomponent
*191792___________ +1.46 +1.330.0040.0080.0151803326382240556.4371_subunitofanaphase-promotingcomplex(cyclosome)
*192991___________ +1.78 +1.720.0000.0000.0012771649360475726.4874_transportprotein
*191585___________ -3.94 -4.290.0000.0000.00017721044957413146.5335_lowaffinityzinctransporter
19989____________ -1.12 -1.220.0100.0810.0102596223254212196.5808_
*19392____________ -1.28 -1.320.0020.0070.0045212940818395316.6272_ubiquinol-cytochromecreductaseassemblyfactor
19527____________ +1.01 +1.010.9730.9830.8411654216636166566.6739_hypotheticalprotein
*193291___________ -1.24 -1.180.0270.0270.0944240034191358246.7186_
*196524___________ -2.18 -1.990.0000.0010.0014402420195221566.7636_translocaseofoutermitochondrialmembrane
*197183___________ +1.24 +1.220.0010.0040.0043015337362368206.8083_conservedhypotheticalprotein
197357___________ +1.06 +1.020.1900.0910.6581505915973153396.8517_conservedhypotheticalprotein
197608___________ +1.02 +1.020.4930.2640.8861287913189131396.8955_
196469___________ -1.07 -1.090.1660.3160.1221233311491112636.413__reversetranscriptase
61051____________ +1.31 +1.240.0020.0040.0081246816383154116.1051_
19985____________ +1.18 +1.130.0060.0120.0201597218816179856.1594_
*19559____________ +1.74 +1.640.0000.0010.0012488443383407726.2138_reversetranscriptase
1921_____________ +1.11 +1.080.5150.3930.5001259713953136546.2654_MPV17homolog
*19274____________ +1.34 +1.300.0040.0070.0151376718460178336.3175_
194739___________ +1.27 +1.130.0050.0070.0301612220449181656.3651_mitochondrialRNAhelicaseoftheDEADboxfamily
195382___________ +1.26 +1.150.0100.0170.0271413617780162526.4144_hypotheticalprotein
*191182___________ +1.60 +2.030.0010.0090.0012228935770451856.4619_
*196121___________ +1.71 +1.610.0010.0030.0042075435481333196.5103_
192332___________ +1.17 +1.120.0130.0100.1211254214683140286.5576_hypotheticalprotein
194949___________ +1.15 +1.030.0430.0210.4671238114191128016.6041_hypotheticalprotein
*19440____________ -2.51 -2.760.0010.0020.0025107220349184876.6509_succinatedehydrogenase
*195171___________ +1.21 +1.080.0090.0060.2512196226566236726.6965_mannosyltransferase
*194002___________ +1.50 +1.520.0010.0040.0031742826137264436.7415_DNAdamageresponse
196402___________ +1.06 +1.060.1190.0840.2741388414754146906.7853_
*195312___________ +1.31 +1.430.0110.1580.0094044452900576756.8301_memberoftheleucinezipperfamilyoftranscriptionalactivators
*197484___________ +2.91 +3.240.0000.0000.000412741201531335426.8736_phosphoribosyl-amidoimidazole-succinocarboxamidesynthetase
19179____________ +1.18 +1.120.0120.0120.0631225414466137726.161__conservedhypotheticalprotein
192222___________ +1.27 +1.210.0060.0120.0211296816504157516.756__
191735___________ +1.28 +1.170.0070.0070.0561284416404150116.1347_hypotheticalprotein
192236___________ +1.25 +1.160.0060.0080.0351364317050158636.1890_
*19738____________ +1.31 +1.310.0040.0100.0131748622829229746.2410_
191202___________ +1.35 +1.300.0080.0140.0231277917239166706.2943_hypotheticalprotein
*192191___________ +1.31 +1.180.0030.0050.0121944025542228626.3427_conservedhypotheticalprotein
*192512___________ +1.51 +1.330.0030.0050.0131779726799236626.3917_hypotheticalprotein
*192876___________ +3.22 +2.850.0000.0000.0002496880426712416.4385_centromere-bindingkinetochoreprotein
*191327___________ +1.30 +1.360.0030.0100.0071590620639215866.4890_
191395___________ -1.22 -1.240.0090.0220.0192638521567213266.5348_mitochondrialphosphatecarrierprotein
196373___________ +1.18 +1.180.0310.0330.0931241614710145916.5824_
195087___________ +1.23 +1.120.0290.0270.1101463017970164176.6288_
*19539____________ +1.92 +1.650.0000.0000.00059360113932980326.6751_DNA-bindingcysteine-typeprotease;bleomycinhydrolase
193304___________ +1.09 +1.060.1140.0960.2122641628692280236.7199_3'-5exoribonuclease
196510___________ +1.04 +1.010.2300.1020.9601236112885124406.7650_glutaredoxin
*197196___________ +8.35 +6.940.0000.0000.0001035058638027183936.8096_vacuolarproteaseB
197369___________ +1.11 +1.250.0180.0430.0301253413869156796.8529_conservedhypotheticalprotein
197620___________ +1.06 +1.070.2370.1220.6031468115547156826.8968_hypotheticalprotein
*193475___________ +4.66 +3.940.0000.0000.000334881560881317786.432__Gagprotein
191534___________ +1.23 +1.200.0030.0050.0131336216479160896.1064_vacuolarZn-ironpermease
191814___________ +1.23 +1.110.0060.0080.0351275815685142086.1616_
*62157____________ +1.70 +1.460.0000.0010.0021752229802255476.2157_
193170___________ +1.31 +1.220.0030.0050.0181375318013167976.2668_
194725___________ +1.34 +1.280.0040.0050.0231365318349174336.3187_transcriptionfactorinvolvedincellcycledependentgeneexpression
*19772____________ +2.40 +2.200.0000.0010.0011969047170433926.3672_
191371___________ -1.22 -1.280.0010.0070.0022624621446204596.4157_
195711___________ +1.27 +1.260.0020.0060.0071550919696194656.4642_
196236___________ +1.29 +1.270.0060.0130.0181654721399210386.5120_conservedhypotheticalprotein
191948___________ +1.16 +1.140.0120.0120.0661562818170177406.5591_
194936___________ +1.06 +1.080.1640.0950.4191241613222134596.6054_hypotheticalprotein
*196627___________ +1.13 +1.120.0120.0200.0333097035009346316.6524_retrovirus-relatedlikepolyprotein
*195159___________ +1.46 +1.140.0010.0010.0264185860949475836.6977_conservedhypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194015___________ +1.05 +1.030.2630.1650.4471495415644154056.7428_Gproteinalphasubunit
194573___________ +1.21 +1.080.0110.0100.0821276015408138266.7872_
*195326___________ -1.39 -1.580.0010.0050.0013336823997210656.8315_transcriptionfactorinvolvedinglucoserepression
*197497___________ +1.51 +1.570.0010.0030.0032574038761403786.8748_
19807____________ +1.03 +1.070.6370.8160.4031535515892164946.174__
191129___________ +1.29 +1.130.0040.0040.0331634221076185306.774__chromatinremodelingSnf/Swicomplexsubunit
192291___________ +1.30 +1.190.0050.0090.0201243616208147916.1363_hypotheticalprotein
194778___________ +1.12 +1.030.0460.0240.3611793420041184606.1907_zincfingertranscriptionfactoroftheLYS14family
*195070___________ +1.54 +1.540.0020.0070.0071533423657236226.2428_hypotheticalprotein
19184____________ +1.11 +1.100.0370.0450.0841238113732136266.2957_
191168___________ +1.39 +1.280.0030.0050.0111322318374169536.3441_potentialfungalZn(2)-Cys(6)binuclearclusterdomainDNAbindingfactor
196025___________ +1.25 +1.260.0020.0050.0081231315434154786.3929_conservedhypotheticalprotein
*193198___________ +1.43 +1.350.0030.0060.0121663323740224566.4401_
195724___________ +1.08 +1.080.0790.0820.1421252213505135776.4903_hypotheticalprotein
192129___________ +1.20 +1.140.0080.0150.0221864022392212856.5363_proteininvolvedinsporewallformation
193872___________ +1.07 +1.080.0820.0580.2351293013796139736.5843_conservedhypotheticalprotein
194401___________ +1.09 +1.100.0560.0590.1201936321069212296.6306_protein-tyrosinephosphatase
66766____________ +1.10 +1.030.1000.0450.6561490416324153036.6766_
193317___________ +1.16 +1.140.0080.0120.0331370915895156526.7212_hypotheticalprotein
195278___________ +1.02 -1.010.7750.6640.6291418314461140106.7664_conservedhypotheticalprotein
197208___________ +1.10 +1.020.2810.1730.4701225713500125336.8108_MAPkinase
*197381___________ +1.15 +1.310.0310.0430.0661379615925180356.8541_zincfingertranscriptionfactor
197635___________ +1.08 +1.050.1040.0690.2831303814085137416.8984_
195531___________ +1.02 +1.000.6870.4180.9291161111897116436.451__
191754___________ +1.49 +1.350.0020.0040.0101247818629168966.1077_
193074___________ +1.08 +1.040.1010.0480.5642070022320215846.1632_hypotheticalprotein
191144___________ +1.30 +1.140.0040.0060.0191292916819147416.2171_
19240____________ +1.14 +1.130.0310.0470.0631410416010158806.2686_conservedhypotheticalmembraneprotein
*193220___________ +1.68 +1.770.0010.0040.0041659027835293436.3201_conservedhypotheticalprotein
195226___________ +1.29 +1.170.0050.0080.0201350617472158456.3687_tryptophan-tRNAligase
195479___________ +1.09 +1.060.0650.0520.1821222613378130046.4173_hypotheticalprotein
195499___________ +1.16 +1.160.0160.0200.0531341815579155426.4658_4-hydroxyphenylpyruvatedioxygenase
193912___________ +1.07 +1.070.0600.0750.1022341325057250146.5136_regulatesglutamine-repressiblegeneproducts
*191842___________ +1.97 +2.260.0020.0050.0091661632792375356.5609_
194175___________ +1.17 +1.040.0270.0130.5051307615298135556.6069_outward-rectifierpotassiumchannel
196641___________ +1.11 +1.070.0480.0380.1651248013855133606.6538_hypotheticalprotein
*196842___________ +1.80 +1.670.0020.0050.0081540427666257196.6990_
194029___________ -1.04 +1.110.4250.7930.2367661973727850126.7442_ribosomalassembly
194589___________ +1.06 +1.020.1740.0980.4481265413404129516.7887_
*195340___________ +1.39 +1.350.0060.0070.0351323718345178156.8329_conservedhypotheticalprotein
*197510___________ +2.60 +3.230.0000.0010.0002556466548825396.8761_
*191504___________ +1.43 +1.420.0030.0060.0162137130644302746.193__
193986___________ +1.28 +1.190.0050.0070.0291263116187150126.793__
192378___________ +1.25 +1.100.0130.0100.1281269215831140196.1382_
192449___________ +1.07 +1.050.7320.4980.7781584016977165926.1921_
192284___________ +1.01 -1.030.4010.2160.7281551215733150756.2444_flavoproteinoxygenase
19612____________ +1.05 +1.040.2140.1080.5981231712897127926.2976_conservedhypotheticalprotein
192923___________ +1.14 +1.120.0230.0180.1271299014830145896.3455_conservedhypotheticalprotein,possibleribosomalprotein
19908____________ +1.06 +1.060.2220.2720.1981473815690156216.3945_
*195580___________ +1.40 +1.440.0060.0150.0141417319795203566.4423_
195736___________ +1.25 +1.310.0060.0150.0131527619148200106.4916_
*192146___________ +1.14 +1.000.0440.0230.3823120135439312296.5378_
193887___________ +1.08 +1.070.0710.0680.1451289013976137636.5858_hypotheticalprotein
*194384___________ +1.77 +1.640.0020.0040.0111313123220215906.6320_
196672___________ -1.44 -1.530.0000.0020.0012760819124180926.6781_heatshockprotein-chaperone
*19341____________ +1.35 +1.510.0070.0150.0171431719399216236.7225_spermidineexporter,MDR-typepump
195265___________ +1.18 +1.090.0190.0220.0691254114855136746.7677_kinesinheavychainhomolog
*197221___________ +1.60 +1.540.0020.0040.0062042932622314366.8120_
197393___________ +1.05 +1.020.3400.2060.5341337614059137106.8553_NADkinaseassociatedwithferricreductase
*197652___________ +1.49 +1.530.0060.0100.0212359835110360806.9001_
192025___________ +1.40 +1.350.0030.0060.0081314718348177976.470__hypotheticalprotein
191742___________ +1.18 +1.220.0060.0100.0191418916736172506.1095_phorphobilinogendeaminase(uroporphyrinogensynthase)|hemebiosynthesis
195579___________ +1.32 +1.170.0020.0040.0171672522007194976.1646_hypotheticalprotein
19657____________ +1.09 +1.100.1030.1030.1651989221589218236.2190_S-adenosylmethioninesynthetase
*192717___________ +1.77 +1.870.0020.0060.0051437825482269516.2703_
*191034___________ +1.46 +1.290.0010.0030.0051744425408224906.3217_putativesteroidbinding
1992_____________ -1.08 -1.340.3070.5170.1919348386396700006.3704_conservedhypotheticalprotein
195491___________ +1.28 +1.190.0050.0070.0241290516542153126.4185_
192574___________ +1.02 -1.050.9910.9060.9705126652508487986.4675_highlyconservedhypotheticalprotein
19224____________ +1.15 +1.080.0130.0110.0961259914494136566.5149_hypotheticalprotein
*19333____________ +2.00 +2.110.0010.0030.0051303426029275316.5625_
192182___________ +1.21 +1.070.0270.0150.3401588719191170366.6081_integralmembraneproteinpossiblyinvolvedinbleomycinresistance
19660____________ +1.34 +1.210.0040.0050.0291387218613167496.6553_hypotheticalprotein
*196854___________ -5.27 -7.030.0000.0000.0009335781772481327236.7003_F1F0-ATPasecomplex,F1alphasubunit
194043___________ +1.04 -1.030.7920.5560.8256086963601589966.7456_
*194602___________ -3.38 -3.810.0010.0030.0025850217332153636.7901_mitochondrialmalatedehydrogenase
195357___________ +1.23 +1.130.0140.0120.0931355616641152686.8346_Ark-familyserine/threonineproteinkinase
197523___________ +1.22 +1.280.0060.0160.0131497818257191916.8776_
194066___________ +1.25 +1.150.0030.0040.0201410117569162406.207__
191175___________ +1.20 +1.120.0050.0070.0301306015688146436.816__hypotheticalprotein
192433___________ +1.18 +1.130.0130.0290.0271370716208154496.1396_hypotheticalprotein
191611___________ +1.15 +1.190.0130.0230.0311306815001155286.1937_
19871____________ +1.22 +1.120.6760.5880.5421552118903173356.2459_
19791____________ +1.07 +1.040.2700.1830.4061204312900125456.2991_serine/threonineproteinkinase
191117___________ -1.18 -1.110.1070.1130.1602168018377194766.3470_
*191510___________ +1.82 +1.700.0030.0050.0121400125537238666.3962_
195592___________ +1.18 +1.070.0200.0150.1491244014715133186.4435_
*191058___________ +1.27 +1.230.0060.0100.0192200427866270996.4931_RPN13-likeconservedprotein
196175___________ +1.18 +1.190.0080.0110.0321868422094222636.5396_conservedhypotheticalprotein
193135___________ +1.05 +1.090.0430.0400.1261344914129146616.5872_conservedhypotheticalprotein
*195114___________ +1.35 +1.360.0000.0010.0014408759355600176.6336_retrievalfromvacuoletoGolgi
*196688___________ +1.26 +1.170.0060.0060.0631990424994233526.6797_hypotheticalprotein
*19354____________ -1.29 -1.210.0010.0020.0053147424390259726.7238_X-Prodipeptidase
195253___________ +1.15 +1.080.0180.0130.1561346015464145476.7689_serine-threonineproteinkinase
197235___________ -1.08 -1.110.2420.1680.3735380449768484756.8135_conservedhypotheticalprotein
197406___________ +1.16 +1.160.0240.0290.0661354215732157496.8567_
*197666___________ +1.23 +1.430.0020.0130.0022108025829300846.9014_permease
19102____________ +1.22 +1.230.0030.0050.0101296115817159136.492__
19581____________ +1.19 +1.060.0760.0810.1354016447717424846.1110_
193156___________ +1.22 +1.120.0100.0110.0571228714991137456.1662_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
195543___________ +1.32 +1.160.0040.0060.0221264116735146896.2203_Vps18protein
194428___________ +1.17 +1.080.0380.0360.1181202214119130266.2719_conservedhypotheticalprotein
193942___________ +1.12 +1.080.0760.0580.2011366515281146906.3229_vacuolarproteinsorting
192792___________ +1.10 +1.070.0200.0170.1071560117140167196.3722_
192351___________ +1.04 +1.010.9020.7650.7802448625364246966.4201_nitrilase
192733___________ +1.21 +1.110.0120.0100.1121477017841164586.4688_
19209____________ +1.06 +1.030.1140.0570.5011324313992136986.5164_possiblerolesinfilamentousgrowth,cellpolarity,andcellularelongation
19319____________ +1.07 +1.080.0790.1260.0931333614312143586.5639_hypotheticalprotein
193428___________ +1.07 +1.050.1800.1360.2951329214264140016.6097_chromatincomponent
19674____________ -1.07 -1.070.2870.3020.2582311221529216946.6567_complexedwithCef1pinspliceosome
191905___________ +1.07 +1.040.1810.1070.4221231213136128486.7016_
192087___________ +1.05 +1.040.1320.0800.3571340314140139246.7469_
194616___________ +1.09 +1.020.0840.0450.3971186112893120776.7915_accessoryfactorforDNApolymerasedelta|ProliferatingCellNuclearAntigen(PCNA)
*197279___________ +1.57 +1.480.0000.0010.0012135433466315036.8360_nitrilasesuperfamilymember
197542___________ -1.07 +1.090.3820.3140.3853598733749391626.8793_
*196308___________ +1.33 +1.220.0030.0070.0101938525878236786.21___
195543___________ +1.09 -1.020.9380.7580.9203942842999386796.514__
193781___________ +1.13 +1.110.0260.0580.0401227213920135826.1130_conservedhypotheticalprotein
*194697___________ +1.33 +1.470.0040.0080.0151564120844230226.1683_
196475___________ +1.08 +1.100.0370.0840.0471197012914131486.2219_
194195___________ +1.00 +1.020.4770.2500.9091325913260135386.2740_hypotheticalprotein
195566___________ +1.09 +1.100.0260.0800.0311304214166143416.3245_lipoateligase
193084___________ +1.04 +1.050.7200.9860.4621256013118132006.3737_involvedinsilencingattelomeres
194420___________ +1.15 +1.160.0110.0220.0261357515613157126.4220_
*192746___________ +1.44 +1.320.0130.0280.0262707239094356316.4702_endosomalprotein
192412___________ +1.23 +1.130.0440.0450.1121730421246196106.5181_involvedingolgitovacuolartargeting
193977___________ +1.14 +1.090.1580.1300.2501642618790179236.5653_probableGTP-bindingprotein
*192909___________ +1.38 +1.270.0100.0380.0151893926109240436.6113_C-3steroldehydrogenase
*192767___________ +2.28 +1.910.0280.0380.064748451706751430136.6585_hypotheticalprotein
191891___________ +1.08 +1.150.0160.0630.0201289613989148136.7028_
192072___________ +1.25 +1.440.0010.0050.0021226015285176106.7483_cholineandnitrogenmustardpermease
194629___________ +1.04 +1.030.3450.2210.4901254113040129706.7928_ubiquitinationpathwayprotein
197293___________ +1.01 -1.010.9840.8680.9931337913451132706.8374_proteinthreonine/tyrosinekinase
196822___________ -1.01 -1.030.5050.9060.2842070520595201566.8809_conservedhypotheticalprotein
Cachs5___________ -1.24 -1.170.0040.0120.0101164294099909Cachs5_
*191335___________ +2.04 +2.330.0000.0020.0004222486058984176.223__
193557___________ +1.07 +1.040.9410.8080.8481965421010203686.835__
*192622___________ +2.40 +2.530.0000.0010.0002210053012558666.1413_GTP-bindingproteinoftherabfamily,involvedinintra-Golgitransport
*191923___________ +1.57 +1.500.0130.0510.0183418753541513856.1958_
191983___________ +1.29 +1.290.0020.0120.0041526119629196816.2477_
63006____________ +1.05 +1.030.2240.2350.2281287013461132776.3006_
63486____________ -1.10 -1.090.1290.1230.1932573223486235746.3486_
*194771___________ +2.41 +2.890.0000.0010.0002122551177612556.3982_carbohydratemetabolism,cellwallmaintenance
195513___________ +1.08 +1.080.1720.1550.2361280513821137886.4454_
*195846___________ +1.19 +1.300.0040.0420.0052544630248331686.4948_transcription/repairfactor
*196189___________ -2.44 -2.600.0000.0010.00114332558742551666.5410_conservedhypotheticalprotein
192258___________ -1.11 -1.080.0690.0650.1472375021490219016.5888_hypotheticalprotein
192008___________ -1.05 -1.100.2550.1590.4433004228554273816.6352_eIF-2Btranslationinitiationfactor
196702___________ +1.05 +1.070.5900.5040.4925723060106613376.6811_asparaginyl-tRNAsynthetase
194442___________ +1.02 -1.010.6230.3600.9734109141971405036.7255_mannosyltransferasethatcatalyzesthetransferofmannosefromDol-P-Mantolipid-linkedoligosaccharides
195239___________ -1.07 -1.080.0750.1860.0661967118433181816.7703_conservedhypotheticalprotein
197250___________ +1.01 -1.040.6770.4220.8412920029391281636.8150_conservedhypotheticalprotein
*197421___________ -1.81 -1.850.0010.0030.0041942371075521051826.8581_cyclophilinD|peptidyl-prolylcis-transisomeraseD
196008___________ +1.03 +1.100.0800.1720.0751333313744146536.9029_conservedhypotheticalprotein
641______________ +1.35 +1.230.0030.0050.0131452619647178236.41___
*191783___________ +1.92 +1.890.0010.0020.0021542329661292106.531__
191786___________ +1.16 +1.110.0130.0180.0441308215203145856.1154_para-aminobenzoatesynthase
193210___________ +1.16 +1.110.0170.0230.0531394616132154886.1700_hypotheticalprotein
*193353___________ +2.45 +2.130.0000.0010.003676531655131438756.2235_
192360___________ +1.40 +1.520.0040.0140.0081538021561234216.2756_
194324___________ +1.15 +1.140.0070.0100.0291844621139209796.3262_conservedhypotheticalprotein
194907___________ +1.07 +1.060.9920.9860.9141361131458131441916.3754_conservedhypotheticalprotein
*194898___________ -2.98 -2.700.0000.0000.00023150577685856806.4234_similartoretroviraltat-bindingprotein
*194665___________ +1.73 +1.730.0000.0010.0011816231487314436.4716_
*194290___________ -1.30 -1.050.0030.0020.1555393241589514116.5195_
196147___________ +1.08 +1.010.2330.1820.3171389615073140516.5667_conservedhypotheticalprotein
*192896___________ -1.41 +1.090.0190.0100.4826280244558684076.6126_peroxisomal2,4-dienoyl-CoAreductase,andsorbitolutilizationprotein
194247___________ +1.00 +1.070.4870.4130.4303895739072417076.6598_
*191877___________ +1.28 +1.250.0180.0550.0252182827997272616.7043_conservedhypotheticalprotein
192060___________ +1.06 +1.030.1680.0940.4491251213253128596.7495_copper-zincsuperoxidedismutase
197017___________ +1.19 +1.130.0100.0130.0401537018319174166.7943_homeobox-domaincontainingprotein
*197306___________ +1.98 +1.980.0000.0000.0002899757362574256.8387_conservedhypotheticalprotein
196809___________ +1.11 +1.040.7680.5430.7783499838761363696.8823_
Caint1___________ -1.00 -1.030.7310.5000.773118901183911507Caint1_
*191770___________ -1.50 -1.350.0050.0070.0238267854958613336.244__cytochrome-cisoform1
*193211___________ +1.61 +1.500.0000.0020.0021768028542265216.849__
*192629___________ +2.38 +1.990.0010.0020.0052160751408430166.1433_
*191945___________ +2.21 +2.050.0000.0010.0002558556589525146.1971_
*194072___________ +1.84 +1.800.0010.0020.0031736231868313166.2489_
194064___________ +1.48 +1.370.0030.0060.0141327219657182256.3021_majorfacilitatorsuperfamilyinvolvedintheattachmentofglycosylphosphatidylinositol(GPI)anchorstoproteins
195188___________ +1.35 +1.230.0040.0070.0191264617013155636.3498_
192935___________ +1.44 +1.470.0610.1190.0691152261661851697086.3999_ribosomalproteinL10
195525___________ +1.09 -1.000.6580.4070.8266586471510658026.4467_conservedhypotheticalprotein
*192472___________ +1.33 +1.300.0010.0020.0031850724636240106.4963_conservedhypotheticalprotein
*196197___________ +2.17 +2.170.0000.0000.0003088666945671076.5426_
194923___________ +1.36 +1.490.0020.0070.0051436019519213726.5903_putativesugartransporter
*191992___________ +1.66 +1.630.0000.0010.0002270337643370826.6367_regulatorofsilencing
*194109___________ +1.18 +1.150.0030.0060.0152509529706288836.6828_
194455___________ -1.04 -1.000.8560.7820.6792723226236271446.7268_hypotheticalprotein
196971___________ +1.15 +1.270.0040.0140.0081640818950208886.7717_glucosyltransferase
*197265___________ -1.47 -1.250.0030.0040.0267036447720562956.8165_snRNPassemblydefective
*197436___________ +3.66 +3.690.0000.0000.000276741011681021386.8596_adhesionandaggregationmediatingsurfaceantigen
69044____________ +1.15 +1.090.0260.0170.2131317215096143476.9044_
1975_____________ +1.18 +1.160.0070.0150.0191218414332141116.59___
191616___________ +1.09 +1.070.0550.0780.0861236613418132516.556__
191522___________ +1.13 +1.220.0230.1280.0201269614350154976.1171_
192555___________ +1.03 +1.010.8180.5830.8441243412750125736.1719_
192285___________ +1.04 +1.090.7590.4900.9581262613086137396.2253_
191307___________ +1.08 +1.080.0430.0620.0741235813360133996.2773_conservedhypotheticalprotein
192851___________ +1.02 +1.030.7670.5630.7351188512105122446.3279_integralmembraneornithinetransporterofmitochondria

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
193465___________ -1.12 -1.190.0690.0920.1032068218464173966.3768_ribosomalproteinL1Athatformspartofthe60Sribosomalsubunit
191837___________ +1.24 +1.130.4220.8020.2332891135797327066.4249_TATA-bindingproteinTBP
193342___________ +1.16 +1.510.0060.0200.0121269214697191226.4734_
194803___________ +1.02 -1.010.5710.6930.3721255812780124706.5209_hypotheticalmembraneprotein
196133___________ +1.14 +1.220.0270.0970.0291500317158183766.5681_
195839___________ -1.06 -1.030.2920.1600.5881209311361117556.6139_lipidbiosynthesisandmultidrugresistance
*194233___________ +1.35 +1.340.0060.0300.0102166629319290326.6612_threoninesynthase
*19511____________ +1.35 +1.270.0040.0100.0131961426394249586.7059_conservedhypotheticalprotein
193815___________ -1.03 -1.010.4730.2940.6141171511346116266.7511_
*197029___________ +1.73 +1.970.0020.0080.0041352823394267066.7955_guaninedeaminase
197319___________ +1.03 +1.040.1440.4240.0881199212383125286.8400_zincfingerproteinSuc1
196795___________ -1.05 -1.070.0560.0410.1941236011725115546.8836_hypotheticalprotein
41020____________ -1.04 -1.030.3330.2210.4601174811320114584.1020_
192907___________ +1.24 +1.200.0050.0090.0171288516006154396.260__
191226___________ +1.23 +1.190.0050.0140.0121300316013155246.866__conservedhypotheticalprotein
*193556___________ +1.41 +1.440.0050.0180.0091350019073194296.1449_
*19254____________ +2.60 +2.140.0010.0050.0032984977460637636.1987_
*19103____________ +1.25 +1.140.0250.0200.1241325516549150626.2506_conservedhypotheticalprotein
191697___________ +1.07 +1.120.0350.0750.0471358914482151626.3036_
194707___________ +1.21 +1.130.0120.0270.0251216614697136956.3512_
19696____________ +1.11 +1.080.0950.0810.1901385815425150306.4012_alpha-factorpheromonereceptor
193185___________ +1.21 +1.260.1870.5800.1025170562505651216.4482_proteinN-acetyltransferasesubunit
193483___________ -1.00 +1.010.5630.3310.7781850218467187666.4976_possibleglycerophosphorylphosphodiesterase
196288___________ +1.03 +1.020.3540.4550.2501237912799126116.5438_hypotheticalprotein
1925_____________ +1.06 +1.030.1950.2540.1761257813283130016.5919_
191417___________ +1.11 +1.070.0800.0810.1471344014898143796.6386_hypotheticalprotein
194094___________ -1.06 -1.080.0560.1240.0601183411178109266.6842_hypotheticalprotein
*19896____________ +1.39 +1.370.0040.0080.0112030128260279036.7281_histidinekinaseosmosensor|two-componentsingaltransducer
*196983___________ +3.33 +3.850.0000.0010.0011524350823586436.7729_conservedhypotheticalprotein
*19930____________ -3.08 -4.510.0010.0030.00222435072927496966.8179_ATP/ADPtranslocator
197449___________ +1.02 +1.020.7440.5960.6421666916969169706.8609_maybeinvolvedinplasmidmaintenance
195980___________ -1.10 -1.020.1870.1080.4442854425948278876.9057_hypotheticalprotein
191746___________ +1.31 +1.140.0120.0130.0581209515864138326.85___
192014___________ +1.22 +1.120.0060.0070.0381585219412177726.574__
19257____________ +1.22 +1.150.0060.0080.0291267015414145966.1190_
194258___________ +1.06 +1.080.1000.0820.2072604427731281066.1734_
196253___________ -1.26 -1.040.2210.1090.6533787323003713655436.2268_ribosomalproteinS23A
*193447___________ +1.93 +2.260.0000.0010.0011914936925432736.2793_
194914___________ +1.27 +1.210.0030.0050.0121938524709233836.3293_conservedhypotheticalprotein
*192929___________ +3.72 +4.850.0000.0000.000345201283221675076.3785_1,3-beta-D-glucansynthasesubunit
192215___________ +1.00 +1.030.8440.6760.7453301633147340116.4260_RNAexportmediator
*192111___________ +1.21 +1.100.0100.0100.0601825422111201296.4750_RNAPolymeraseIItranscriptioninitiationfactorTFIIFmiddlesubunit
194817___________ -1.10 -1.060.0590.0750.1002406221952228056.5223_geranylgeranyltransferasetypeIalphasubunit|CAAXfarnesyltransferasealphasubunit
19581____________ +1.17 +1.050.0310.0250.1401473117293154846.5698_
*195826___________ +3.46 +2.840.0000.0010.0021277644185363166.6152_GABA-specifictransportprotein
195796___________ +1.03 +1.130.1440.3410.0982446925318277006.6628_
*19497____________ +1.40 +1.460.0020.0050.0042846439886414806.7074_hypotheticalprotein
193831___________ +1.16 +1.120.0290.0260.1141479117124165016.7525_
197043___________ +1.08 +1.040.1020.0850.2031256413587130756.7969_conservedhypotheticalmembraneprotein
197331___________ +1.19 +1.120.0070.0100.0271308615588146816.8412_purine-cytosinetransportprotein
*196783___________ +1.18 +1.170.0180.0160.0892191425811257486.8848_geranylgeranyltransferaseregulatorysubunit
42107____________ +1.09 +1.010.2290.1330.4721549816921156324.2107_
*19223____________ +1.61 +1.430.0040.0060.0191448223356206526.278__
19776____________ +1.22 +1.170.0160.0230.0441344916366157596.891__
192659___________ -1.12 +1.070.9840.9920.8763142622817233355016.1464_conservedhypotheticalprotein
*191678___________ +1.17 +1.200.0030.0070.0132874333507344896.2000_hypotheticalprotein
193361___________ +1.01 -1.040.9480.7660.9871820218403175116.2526_carnitineacetyltransferase
*194885___________ +1.31 +1.420.0240.1240.0223574946663507516.3051_mitochondrialphosphatetransportprotein
*19642____________ +1.56 +1.480.0010.0020.0032296735906340056.3529_SIT4proteinphosphatase-associatedprotein
195373___________ +1.31 +1.270.0030.0060.0121400418302177456.4028_
*192835___________ -1.29 -1.130.0070.0080.0513931230438347696.4496_protein-sumoylationfunction,partofactivatingenzymeforSmt3
193470___________ +1.27 +1.090.0110.0100.0791476718795161506.4989_
*194681___________ +1.60 +1.900.0000.0020.0012885046054549196.5455_5'-3'exoribonuclease
19201____________ +1.15 +1.110.0300.0320.0911313315041145286.5933_
191542___________ +1.13 +1.040.0120.0100.1051675218899174576.6400_hexomemetabolism
*194082___________ -4.04 -3.330.0000.0000.00022145054872665736.6854_flocculentspecificprotein|containsNNDDNSYGmotif
*19880____________ +1.20 +1.130.0030.0040.0182156625824244126.7297_sec-24-likemembraneproteininvolvedinERtoGolgivesiculartransport
196995___________ +1.05 +1.020.4990.5560.3521436215061146206.7741_FUN34-relatedprotein|glyoxylatepathwayregulator
19943____________ +1.18 +1.110.0190.0160.1081273814988141136.8192_multicopperferro-O2-oxidoreductase
*195387___________ +1.51 +1.490.0010.0030.0031870628254277826.8623_vacuolarsortingprotein
195967___________ +1.10 +1.080.0510.0410.1671456315980157046.9070_conservedhypotheticalprotein
193998___________ +1.06 +1.040.1810.1490.2671210812798125596.105__
195422___________ +1.03 +1.020.7400.5090.7781502015487152956.597__weaklyconservedhypotheticalprotein
191821___________ +1.05 +1.050.4240.7130.2451178412332124166.1209_hypotheticalprotein
191185___________ +1.00 +1.040.2320.5550.1331368413692142146.1751_
193768___________ +1.07 +1.070.0440.1690.0381221613018131046.2285_conservedhypotheticalprotein
19405____________ +1.01 +1.000.8040.6570.6871283812983128636.2814_
193655___________ +1.03 +1.010.7930.6260.7001182412152119756.3307_
195717___________ -1.00 -1.020.4900.2790.7351234912324121496.3802_hypotheticalprotein
192610___________ +1.11 +1.060.1090.0580.4351313014634139826.4275_proteinwithspecificaffinityforG4quadruplexnucleicacids
192367___________ -1.02 +1.020.4820.7190.2881211711823123956.4765_conservedhypotheticalprotein
194135___________ +1.11 +1.080.2220.1170.5611460816157158076.5243_
192977___________ -1.00 -1.040.5250.7300.3221370813702131636.5713_
192484___________ +1.02 -1.010.9230.8930.7441452014881144036.6165_highlyconservedhypotheticalprotein
195809___________ +1.02 +1.010.5560.3970.5701310613308132096.6643_biosynthesisofnicotinicacid|kynurenineaminotransferase|glutamine-phenylpyruvatetransaminase
19482____________ -1.04 -1.050.3960.3030.4261244611976118226.7088_
193846___________ -1.04 -1.030.3030.1760.5311160011104112526.7542_
195026___________ +1.05 +1.040.2600.2080.3251469815495152626.7983_homolofoustoZincFingerProteinC2H2
197345___________ -1.03 -1.060.1540.5550.0841338012981126466.8426_predictedkinase
196770___________ -1.19 -1.190.0060.0140.0142620421987219466.8861_epsinN-terminalhomology-containingprotein
42498____________ -1.02 -1.040.5150.6890.3231175311524113094.2498_
192454___________ +1.12 +1.030.9770.8440.9943214035971330456.293__
*191294___________ +1.36 +1.330.0050.0120.0131346518350178906.912__
193625___________ +1.14 +1.100.0120.0260.0261289814697141266.1480_PHD-fingerprotein
191746___________ +1.20 +1.120.0120.0170.0431272315297142916.2019_
194768___________ +1.19 +1.100.0140.0200.0421355416096148446.2540_hypotheticalprotein
193791___________ +1.06 +1.070.4720.9700.2581414615021151566.3064_asparaginase-likeprotein
*19864____________ +1.19 +1.150.0370.0600.0611852222095213156.3550_proteininvolvedindecayofmRNAcontainingnonsensecodons
195816___________ +1.18 +1.090.0180.0200.0681297015306141586.4043_NAPDHdehydrogenase(oldyellowenzyme)|estrogen-bindingprotein
*195642___________ -1.52 -1.540.0150.0150.0705951423915003855926.4511_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194508___________ +1.09 +1.090.0310.0590.0501197913068130226.5003_hypotheticalprotein
193738___________ +1.13 +1.100.0420.0600.0751270114364139966.5468_hypotheticalprotein
195148___________ +1.03 +1.030.2580.1850.3681238812811128176.5947_
*191555___________ +1.35 +1.380.0050.0280.0072039727611281796.6413_
*196719___________ +1.35 +1.260.0270.0460.0503662449296459776.6868_regulatorofhistonetranscription
*196924___________ +4.82 +4.080.0000.0000.000576332776632352776.7310_histoneH2A
193018___________ +1.03 +1.040.4130.6560.2451236412762128016.7754_
19956____________ +1.04 +1.010.3820.2130.6581341813944136096.8207_
195400___________ -1.02 -1.050.3670.4020.2881558315290148286.8636_
195953___________ +1.10 +1.190.1470.4560.0862554228004302836.9084_splitzincfingerprotein
*194168___________ +1.56 +1.520.0000.0010.0012173233867329836.124__RNAseP/MRPsubunit|RNAprocessing
*193752___________ +2.53 +2.640.0000.0010.0001866047293492756.615__
*19860____________ +1.28 +1.160.0020.0030.0181863523812215966.1229_
193161___________ +1.31 +1.310.0010.0050.0041621021274211716.1772_
193937___________ +1.07 +1.080.1340.2710.1041273213640137716.2300_
194423___________ +1.21 +1.130.0140.0130.0811318715906149346.2832_
195043___________ +1.21 +1.110.0060.0060.0491250915087138656.3321_
192645___________ +1.19 +1.050.0170.0120.1821258014963132116.3818_hypotheticalprotein
*193543___________ +1.21 +1.250.0030.0120.0072152926015269936.4289_hypotheticalprotein
*195622___________ +3.94 +4.080.0000.0000.000694872735012835666.4781_alpha-1,4-glucanbranchingenzyme
196555___________ +1.33 +1.220.0030.0050.0111376818288168246.5259_
*191259___________ +1.70 +1.590.0000.0010.0012551243386405756.5726_conservedhypotheticalprotein
192500___________ -1.01 -1.070.1960.5690.1091614215913150586.6181_conservedhypotheticalprotein
66657____________ +1.07 +1.050.1450.0950.3301241013287130446.6657_
*191468___________ +1.75 +1.640.0000.0000.0013438160133562276.7105_ser/thrphosphatase2AregulatorysubunitB
*196573___________ +1.62 +1.370.0020.0030.0111789829054244506.7559_
195013___________ -1.00 +1.000.7800.5170.9131661116554166946.7996_phosphoacetylglucosaminemutase
197114___________ +1.05 +1.020.3150.1650.6661239812964125906.8440_
*196756___________ +1.17 +1.170.0060.0120.0183131636734366526.8875_conservedhypotheticalprotein
42736f--1________ -1.01 -1.060.3500.8280.1831311212922124094.2736f
*193526___________ -2.14 -1.790.0010.0020.00316687077881933086.310__
191495___________ +1.26 +1.140.0080.0110.0361403517687160676.934__hydrolase
*193531___________ +1.34 +1.310.0010.0030.0061895825456247436.1499_hypotheticalprotein
*193523___________ +1.58 +1.590.0010.0030.0032890945586459996.2036_
193782___________ +1.17 +1.100.1900.1060.4772173425362240086.2554_acetyl-coenzymeAtransporter
6308_____________ +1.12 +1.050.0870.0600.2511270414203134036.3080_
192276___________ +1.19 +1.130.0110.0110.0671540518369173546.3565_DNA-directedRNApolymeraseII
*193920___________ -1.38 -1.270.0000.0010.0023169822903248796.4056_disulfideisomeraserelatedprotein
*196217___________ +1.92 +1.860.0000.0010.0011819434934338396.4528_
*194203___________ +1.31 +1.450.0000.0020.0013748049143541806.5018_nuclearenvelopeprotein
192694___________ +1.06 +1.080.0200.0210.0771255613295135026.5482_tyrosyl-tRNAsynthetase
194740___________ +1.19 +1.110.0060.0060.0641273915199141266.5963_
*191569___________ +1.59 +1.730.0000.0010.0002597541372450186.6426_U3protein
196732___________ +1.15 +1.070.0180.0150.1041904621913203816.6882_
*196938___________ -1.33 -1.160.0090.0090.0603298424782285056.7324_regulatorofADH2expression
193031___________ -1.05 -1.020.3290.1950.5372743826230267926.7768_subunitofERprotein-translocationcomplex
19971____________ +1.13 +1.070.0440.0330.1751746419813187286.8220_transcriptionfactor
*195416___________ +1.18 +1.230.0110.0200.0293210637790394516.8650_
*195938___________ +1.77 +1.540.0010.0030.0072206739045340616.9100_
19123____________ +1.05 +1.080.0710.1660.0661395214634150856.138__hypotheticalprotein
19446____________ +1.05 +1.030.2920.1880.4511236212973127656.646__
19922____________ +1.06 +1.040.1560.1880.1671190812577123826.1245_
192911___________ +1.12 +1.110.0250.0390.0531367315260151396.1788_
191038___________ +1.02 +1.080.4690.4740.3611207412366130426.2319_hypotheticalprotein
191192___________ +1.03 +1.060.3040.4470.2061197512336126756.2845_
194890___________ +1.11 +1.150.0220.0380.0461308814585150246.3335_
194873___________ +1.03 +1.020.8490.9510.6121209612495123516.3832_hypotheticalprotein
194482___________ +1.20 +1.200.0090.0160.0261256215110150576.4305_
*192688___________ +1.27 +1.370.0030.0180.0041433618199195906.4799_
*196544___________ +1.62 +1.940.0030.0110.0061584025677306876.5272_
191663___________ -1.01 -1.000.9340.7370.9711305212930129976.5738_alpha-1,2-mannosyltransferase
195759___________ -1.05 -1.020.3690.2820.4091186811341116336.6199_ABCtransporter
192946___________ +1.10 +1.140.0140.0590.0181504816503172246.6670_cholinepermease
191453___________ -1.06 -1.050.1760.2160.1761451013671137596.7118_
196585___________ -1.01 -1.050.3800.8680.2001190211745113366.7573_conservedhypotheticalprotein
194998___________ -1.00 -1.010.9140.7010.9501207212028119856.8011_TY1enhanceractivator
197102___________ -1.03 +1.040.5950.5810.4431267212354131606.8451_conservedhypotheticalprotein
196742___________ +1.06 +1.060.2230.2420.2211210112869128156.8888_
42838____________ +1.00 -1.030.7890.6310.6861190611954116144.2838_
*19267____________ +1.82 +2.000.0010.0030.0021948635442388766.326__
*192331___________ +1.40 +1.280.0030.0040.0272115729564271146.952__
*193622___________ +1.67 +1.740.0020.0120.0022262937751392716.1514_mannan8|Golgimannosyltransferaserequiredforproteinglycosylation
193593___________ -1.05 -1.080.3410.2630.3892746526150253176.2051_
19103____________ +1.10 +1.080.1060.1420.1261412015505152206.2573_
194560___________ +1.13 +1.110.0170.0350.0331447016338161016.3091_
*192204___________ +2.31 +2.650.0020.0130.0032327753789615876.3580_conservedhypotheticalmembraneprotein
194666___________ +1.03 +1.010.8800.6870.8262424524871244356.4070_hypotheticalprotein
*194377___________ +2.35 +3.090.0000.0020.0002046848021631986.4542_cellwallbeta-1,6-glucanassembly
193324___________ -1.13 -1.160.1930.1000.5541776281578561531706.5030_translationinitiationfactor4A
196307___________ +1.37 +1.410.0030.0110.0071304417841184226.5500_hypotheticalprotein
*192038___________ +1.81 +2.210.0000.0030.0001589628728351766.5977_hypotheticalprotein
*191632___________ -1.52 -1.320.0080.0070.0955364435212407826.6440_GPI-anchoredproteinwithcellwallrole
195657___________ +1.04 -1.030.7670.6470.6312690528011261296.6897_componentofSWI/SNFglobalactivatorcomplex
196955___________ +1.12 +1.130.0830.4340.0481952021919219926.7340_
193047___________ +1.01 -1.010.7060.4420.8892905429328288986.7784_interactswithSnf1pprotein
193234___________ -1.09 -1.130.0270.0460.0511632514941144806.8234_NADPHdehydrogenase
195428___________ +1.08 +1.110.0830.1620.0811466315806163156.8663_
195925___________ -1.11 -1.110.0360.0450.0781792216085162126.9112_conservedhypotheticalprotein
193788___________ +1.48 +1.460.0010.0030.0041435021207208986.152__hypotheticalprotein
19153____________ +1.19 +1.120.0130.0180.0401261814959141276.661__
*191864___________ +1.84 +1.850.0010.0030.0031453626699269086.1264_
*193393___________ +1.45 +1.800.0000.0030.0003231847013581716.1808_dead-boxprotein9
191646___________ +1.04 +1.070.3250.8270.1685092852882546186.2337_
19925____________ -1.00 -1.020.3460.1880.6511732417274170466.2863_hypotheticalprotein
192653___________ +1.41 +1.510.0660.3830.0402245831713339976.3350_hypotheticalprotein
19836____________ +1.19 +1.060.0110.0080.1331263515009134376.3847_hypotheticalprotein
194468___________ -1.23 -1.360.1060.0880.20812081598114885676.4318_
19286____________ +1.12 +1.060.0340.0290.1341343315076142356.4815_hypotheticalprotein
*193004___________ +3.30 +4.630.0000.0000.00022455740841040416.5284_
193578___________ +1.07 +1.040.0980.1090.1441301813870135946.5751_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
196602___________ +1.22 +1.200.2830.7430.1481600919513192236.6214_conservedhypotheticalprotein
*194536___________ +1.17 +1.300.0080.0430.0116497575896846286.6682_cystathioninebeta-synthase
*196868___________ +1.17 +1.170.0020.0060.0063045535612356986.7132_GRE2-relatedproteinfamily|cinnamyl-alcoholdehydrogenase
196041___________ -1.03 -1.100.0900.3860.0552602225344237066.7585_mitochondrialDNA-directedRNApolymerase
194983___________ +1.12 +1.130.0110.0490.0151644818436185696.8026_
*197086___________ +1.99 +2.010.0010.0040.0041832236429367726.8466_
197553___________ +1.09 +1.200.0170.0420.0271314314300158276.8901_hypotheticalprotein
42923____________ +1.00 -1.040.4360.5060.3101198711991115314.2923_
*191509___________ +1.87 +1.660.0020.0040.0091521028485253066.344__O-dinitrobenzene,calciumandzincresistanceprotein
195869___________ +1.29 +1.240.0030.0060.0161352317403168096.970__metalhomeostasisprotein
*61531____________ +1.35 +1.310.0020.0050.0061824124548239406.1531_
193640___________ +1.31 +1.170.0050.0050.0461306817077152336.2073_glutaminegamma-glutamyltransferase
19866____________ +1.42 +1.450.0040.0080.0111497221272217376.2591_
194275___________ +1.54 +1.440.0020.0050.0071446822256208636.3110_
*192604___________ +1.77 +1.720.0020.0060.0071436625405247056.3595_highlyconservedhypotheticalprotein
*191764___________ +3.67 +3.520.0000.0000.0002604995620918156.4085_hypotheticalprotein
195679___________ +1.17 +1.130.0280.0280.0971226814324139096.4557_methionineN-acetyltransferase
191961___________ -1.09 +1.140.1080.2080.0964000136563456146.5044_
*196322___________ +1.66 +1.910.0000.0000.0001310802169642506236.5515_D-arabinitoldehydrogenase
*192050___________ +1.42 +1.700.0010.0050.00168302970691161816.5989_triglyceridelipase-cholesterolesterase
193448___________ +1.22 +1.230.6440.7520.4256258276400767906.6457_hypotheticalprotein
*195671___________ +1.53 +1.390.0010.0020.0032173633182301116.6910_
*194853___________ +1.48 +1.430.0040.0080.0121504022212214336.7357_
193058___________ -1.15 -1.140.0390.0700.0592533421946221596.7795_COQ6monooxygenase,coenzymeQbiosynthesis
*193247___________ +1.56 +1.620.0000.0010.0012856144556463526.8247_highlyconservedhypotheticalprotein
195441___________ +1.26 +1.240.0080.0150.0231368117199169716.8677_ubiquitin-like-specificprotease2
*195911___________ +3.67 +3.870.0000.0000.000523221921362024016.9126_Ca2+/calmodulin-dependentproteinkinase
1968_____________ -1.06 -1.060.0700.2400.0531330512560125696.27___possibleN-terminusofBNI4
192160___________ +1.10 -1.030.0680.0310.5943108634262301626.680__
191930___________ -1.02 +1.020.8530.6160.8961167411397119046.1282_
*191750___________ +2.19 +1.750.0000.0000.000633241385811110686.1827_hypotheticalprotein
192542___________ +1.40 +1.310.0040.0100.0111457620417190506.2351_similartodnaJproteins
193695___________ +1.05 +1.050.1450.0940.3381335414036140436.2882_
*192529___________ +2.52 +1.930.0000.0010.0021939448928374466.3368_conservedhypotheticalprotein
192386___________ +1.13 +1.040.6480.4030.8003546140241368166.3862_U3snoRNPprotein
*193399___________ +1.42 +1.290.0050.0080.0212040029056263076.4334_
*19600____________ +2.02 +2.320.0010.0060.0021636432988379296.4830_
*191365___________ +1.26 +1.110.0050.0060.0462610632835290426.5297_coenzymeF420-dependentN5,N10-methylenetetrahydromethanopterinreductase|flavin-dependentoxidoreductase
193563___________ +1.06 +1.020.2840.1420.6951265113469128626.5766_hypotheticalprotein
*196112___________ -1.15 -1.480.0010.1950.0012471612154731667826.6230_putativetranscriptionalactivator
*194550___________ +2.87 +2.810.0000.0000.0002006557652563606.6696_membranetransporter
*196882___________ +1.07 -1.220.0470.0600.0877329607835426010506.7146_fumaratereductaseflavoproteinsubunit
*196055___________ +1.64 +1.410.0010.0020.0072932247962412946.7599_ubiquitinationpathwayprotein
197141___________ +1.06 -1.210.1930.3650.1343610438430298296.8042_
197073___________ +1.11 +1.150.0930.0720.2161889420914217706.8480_cpnservedhypotheticalprotein
197567___________ +1.02 -1.000.5130.2750.9451460014922145286.8915_conservedhypotheticalprotein
43047____________ -1.02 +1.010.9750.8780.8961184511563119654.3047_
*19556____________ +1.74 +1.630.0000.0000.0002579444878421426.363__hypotheticalprotein
19478____________ +1.39 +1.320.0010.0030.0041585822008209936.989__
195530___________ +1.19 +1.090.0270.0200.1661290915338141256.1544_
*195750___________ -1.06 -1.290.0130.5330.0088704082387674976.2091_serinehydroxymethyltransferase
19123____________ +1.17 +1.120.0110.0120.0531671519579187426.2608_
194713___________ +1.25 +1.100.0170.0180.0711242115577137136.3126_hypotheticalprotein
192791___________ +1.16 +1.110.0150.0170.0602145624971237926.3610_
*192598___________ +2.88 +2.740.0000.0000.000477521376261310516.4100_vacuolarH+-ATPaseV1domainsubunit
195693___________ +1.01 -1.020.5830.3760.6792851028732278936.4572_
195866___________ +1.03 +1.050.6880.4230.9021345613801141126.5058_hypotheticalprotein
192317___________ -1.04 +1.070.4950.2650.9001277812258136216.5533_hypotheticalprotein
196453___________ +1.09 +1.020.1470.0650.7771228413343124886.6005_
*193436___________ +1.64 +1.730.0000.0020.0011720028128297046.6469_hypotheticalprotein
*193122___________ -1.25 -1.280.0020.0050.0063140225095244396.6923_involvedinarsenitetransport
*194837___________ +1.18 +1.090.0070.0070.0672141025182233976.7373_
196447___________ +1.01 +1.000.7730.5310.8231199212061120426.7807_ADP-ribosylationfactor|GTP-bindingproteinoftheARFfamily
193261___________ +1.05 +1.090.0590.0510.1581358814255147966.8261_hypotheticalprotein
*195454___________ +4.97 +4.680.0000.0010.0001658582382776226.8689_
195896___________ -1.00 -1.010.9220.7330.8931206612028119626.9141_conservedhypotheticalmembraneprotein
193111___________ +1.35 +1.200.0040.0060.0271424619181171376.60___
*194906___________ +2.37 +3.060.0000.0010.0001810242906554476.699__
195544___________ -1.18 +1.050.5530.3040.9351835441552831921716.1297_
*194631___________ +1.14 +1.610.0010.0410.0011237791416721991106.1843_
*1946391__________ +1.39 +1.400.0000.0020.0013805252774533646.2369_
191276___________ +1.05 +1.020.2030.0940.7521525415955155576.2899_weaklyconservedhypotheticalprotein
195056___________ +1.40 +1.260.0030.0070.0131427820048180036.3380_anaphasepromotingcomplexcomponent
*193688___________ +1.66 +1.770.0000.0000.0003703861572655446.3878_responsetodessication
192194___________ +1.42 +1.300.0030.0060.0131329718861172496.4347_mediumsubunitofclathrinassociatedprotein|AP-2complexsubunit
*191716___________ +1.26 +1.130.0120.0170.0432584132549292716.4844_orotidine-5'-phosphatedecarboxylase
*193713___________ +7.77 +8.010.0000.0000.000268702089092150976.5311_hypotheticalprotein
*196351___________ +1.45 +1.620.0020.0060.0061702424605275126.5781_
*196099___________ -1.98 -1.820.0000.0000.0002122181070511164306.6242_componentofchaperonin-containingT-complex
19820____________ +1.08 +1.180.1140.3110.0793724240380439096.6712_
196898___________ +1.08 +1.020.8870.6520.9822261124465230216.7162_conservedhypotheticalprotein
*196068___________ +1.31 +1.180.0020.0030.0141851624298218536.7611_
197157___________ +1.11 +1.050.0340.0210.2611355715105141916.8057_hypotheticalprotein
*197060___________ +2.28 +2.200.0000.0000.0002785363590612386.8493_hypotheticalprotein
*197581___________ +2.31 +2.300.0000.0010.0012457056777565716.8930_
19616____________ +1.22 +1.140.0100.0090.0791222914934139136.381__hypotheticalprotein
19773____________ +1.35 +1.330.0040.0090.0131377818641183386.1015_
192925___________ +1.18 +1.100.0290.0370.0691215214295133776.1561_GTP-bindingprotein
191481___________ -1.07 -1.010.2780.1720.4662360121996234166.2105_hypotheticalprotein
194162___________ +1.14 +1.030.0870.0460.4081218013841125596.2626_DNAmismatchrepairprotein
194972___________ +1.06 +1.020.3180.1610.7151242913230126566.3141_
195542___________ +1.26 +1.270.0050.0100.0151274016034161686.3624_candidapepsin6precursor
*19780____________ +1.58 +1.360.0060.0090.0271258819900171476.4116_ureaamidolyase
192805___________ +1.08 +1.090.3060.4400.2102427426243264006.4586_
195599___________ -1.05 -1.010.3670.1820.8522057219633204066.5073_
192303___________ -1.01 +1.130.0150.5000.0092052520316231206.5547_conservedhypotheticalprotein
*19726____________ +1.23 +1.430.0010.0070.0012023624894289056.6017_ser/thrphosphataserequiredfornormalosmoregulation
*193672___________ +1.84 +2.220.0000.0010.001654311201191450626.6483_UDPglucose-4-epimerase
193108___________ -1.03 +1.050.9190.7130.9342500424217263096.6937_O6-methylguanineDNArepairmethyltransferase
*194824___________ -1.31 -1.000.0060.0040.6258026561288802596.7387_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*196432___________ -1.21 -1.130.0160.0100.2662850023544251836.7822_AAAfamilyofATPases
*193273___________ +1.13 +1.360.0020.0170.0022875832395389726.8274_
195469___________ +1.09 +1.070.0460.0540.0961635217828175386.8707_
195880___________ +1.27 +1.100.0100.0110.0541476418802161986.9155_
*193740___________ +1.28 +1.270.0010.0030.0042137227263270646.83___hypotheticalprotein
193193___________ +1.24 +1.160.0050.0060.0291336216561155506.716__
*192121___________ +6.75 +3.930.0010.0020.006335204226324313182796.1311_
*191525___________ +2.02 +1.620.0010.0020.0032108042561342216.1860_
192017___________ +1.55 +1.350.0060.0110.0211315220422177346.2382_
*1928471__________ +6.80 +4.480.0000.0000.000757955155623395606.2912_NA
*191517___________ -1.45 -1.700.0000.0020.0015037234832296466.3396_2-dehydro-3-deoxy-phosphoheptonatealdolase
*191339___________ +1.35 +1.190.0010.0010.0151303201757591555506.3892_
193499___________ +1.09 +1.100.0230.0400.0471470416027162136.4359_hypotheticalprotein
195788___________ -1.12 -1.100.0250.1590.0211210410834110506.4858_
196163___________ -1.13 -1.120.0200.0470.0311154610229103216.5324_histoneH3variant
191003___________ +1.19 +1.070.0300.0230.1511369316255146216.5794_hypotheticalprotein
196082___________ -1.01 -1.070.5890.7650.3711176011681110056.6259_involvedinglucoserepression
19513____________ -1.19 -1.130.0070.0200.015118529973105156.6725_DNAbindingtranscriptionfactorthatactivatesmiddlesporulationgenes,inS.cerevisiae
196910___________ -1.16 -1.120.0100.0250.0211192310265106546.7174_DNAdependentDNAreplication
1965342__________ -1.11 -1.150.0270.1260.0251276211487111286.7625_NA
197170___________ -1.12 -1.120.0090.0360.0131169710405104016.8070_hypotheticalprotein
197047___________ -1.17 -1.130.0170.0400.030116209968102486.8505_
197596___________ -1.21 -1.140.0100.0230.022116869697102906.8944_PhosphoMUtasehomolog
19522____________ +1.23 +1.200.0040.0050.0241259715482150646.395__
*194264___________ +1.84 +1.600.0010.0030.0061344024758214956.1033_
191803___________ +1.21 +1.090.0160.0110.1541247715140135916.1576_
191041___________ +1.40 +1.380.0020.0050.0051425819903197046.2123_RNApolymeraseIIC-terminaldomainkinasebetasubunit
*193643___________ +1.44 +1.400.0040.0090.0131504421680211156.2641_
*196030___________ +1.41 +1.190.0010.0020.0072217331278263706.3158_hypotheticalprotein
19760____________ +1.03 +1.010.3130.1460.9941475215123148486.3639_mitochondrialribosomalL36protein
19741____________ +1.01 +1.000.5980.7900.3731443614578144696.4130_hypotheticalprotein
194299___________ +1.03 +1.060.5800.6600.3911569516240167136.4605_
191228___________ +1.05 +1.000.2240.1230.5211249513074125176.5088_
*192672___________ +1.65 +1.650.0000.0000.0004759578685785976.5562_NADPH-cytochromeP450reductase
196271___________ -1.01 -1.030.7550.5140.8051234012219119246.6030_conservedhypotheticalprotein
19427____________ +1.19 +1.090.0390.0260.2111272215117138996.6496_RAP1-interactingfactor,involvedinestablishmentofrepressedchromatin
*193093___________ +2.08 +2.280.0010.0050.0041386928904315966.6951_
*193991___________ +1.45 +1.310.0000.0010.0013369348851442866.7404_predictedalpha/betahydrolase
196416___________ +1.04 +1.050.2950.2710.2981251613054130936.7839_
*195300___________ +1.30 +1.330.0010.0040.0032035426523270226.8288_
197472___________ +1.36 +1.180.0040.0070.0201401219077165876.8723_
*1984_____________ +2.83 +2.740.0000.0010.0011329637594364536.115__argininepermease
*191099___________ +2.82 +2.130.0010.0020.0031502642437320156.738__hypotheticalproteininMajorRepeatSequence
*192758___________ +2.69 +2.320.0000.0000.0002515167619582356.1331_
*191208___________ +2.25 +2.800.0010.0040.0021544234715432176.1877_involvedinfungalinduction
192237___________ +1.29 +1.130.0060.0060.0661270016345143406.2395_exo-1,3-beta-glucanase
193384___________ +1.49 +1.280.0010.0030.0051589123628202956.2931_
*195197___________ +2.09 +1.900.0010.0030.0041488431116282906.3413_alanine/arginineaminopeptidase
*195214___________ +1.16 +1.240.0090.0390.0133024435215375886.3905_vacuolarsortingproteinessentialforvacuolarmorphogenesisandfunction
*191793___________ +1.85 +1.930.0000.0000.0002094738753404666.4372_conservedhypotheticalprotein
*191313___________ +2.24 +2.070.0000.0000.0002716860768561476.4875_
191584___________ +1.20 +1.130.0030.0050.0161817521851206226.5336_similaritytomonocarboxylatetransporters
*19988____________ +1.31 +1.470.0000.0020.0012598434066380736.5810_
*19391____________ +2.57 +2.080.0000.0010.0021884348388391936.6273_transcriptionalregulatorofthesterolbiosynthesis
*19528____________ +1.33 +1.380.0010.0050.004859861140921189256.6740_coatomercomplexbetachain
*193292___________ -1.34 -1.090.0060.0070.0405037137647462536.7187_
196522___________ +1.14 +1.130.0190.0220.0671967822473222126.7637_
197184___________ +1.07 +1.030.7240.5700.6342611427955269016.8084_vacuolarproteinsorting
197358___________ +1.06 +1.060.3780.2240.5841694417999179356.8518_conservedhypotheticalprotein
197609___________ +1.05 +1.030.1630.0820.5501624617107167446.8957_hypotheticalprotein
193100___________ -1.06 -1.090.1800.2780.1471184311178108286.414__
191440___________ +1.17 +1.140.0450.1460.0421220214235139106.1052_hypotheticalprotein
19989____________ +1.10 +1.020.1510.0670.7311409515527144116.1598_
19562____________ +1.14 +1.110.0170.0160.0801278814540142286.2139_
1922_____________ +1.17 +1.080.0470.0320.2091214714266131526.2655_
19273____________ +1.24 +1.140.0060.0070.0401279815927145346.3176_conservedhypotheticalprotein
194740___________ +1.05 +1.050.2620.1910.3651574016454164716.3652_peptidyl-tRNAhydrolase
*195383___________ +1.47 +1.540.0000.0010.0002193532294336946.4145_plasmamembraneH+-ATPase
191185___________ -1.01 +1.080.3460.6290.2002788027651300926.4622_conservedhypotheticalprotein
*196121___________ +1.62 +2.300.0000.0030.0002106634025484026.5101_
192331___________ +1.23 +1.320.0020.0100.0031566619347206236.5577_transcriptionfactor,memberofADAandSAGAcomplexes
194948___________ +1.00 -1.000.7740.5220.8601226412314122536.6042_RNAexonuclease
*19442____________ +1.04 +1.290.0070.1800.0053072931947395416.6511_
*195170___________ +2.47 +3.440.0000.0000.000528061304401817266.6966_P-typeATPaseinvolvedinNa+efflux
194003___________ -1.03 -1.020.5510.9880.3171513214685148036.7416_ERtoGolgitransport
196398___________ -1.02 -1.050.6110.9640.3651268412406120406.7857_
*195313___________ -1.36 -1.190.0010.0010.0162936321577247126.8302_hypotheticalprotein
197485___________ -1.70 -1.500.0070.0100.0282886417005192656.8737_mitochondrialribosomalproteinofthelargesubunit
191401___________ -1.06 -1.060.1710.2240.1641169011034109796.162__
*193792___________ +1.27 +1.100.0050.0040.1992068726285227586.757__
*191736___________ +1.89 +1.430.0110.0160.0361564929506223596.1348_
192236___________ +1.30 +1.220.0070.0110.0291307317056159256.1891_
19740____________ -1.16 -1.410.0130.0610.0162838624423201716.2411_hypotheticalprotein
191201___________ +1.16 +1.050.0720.0320.6341473717053155136.2944_similartobacterialseryl-tRNAsynthases
*192192___________ -1.27 -1.550.0310.0870.0363213025386207566.3428_NAD-specificglutamatedehydrogenase
192513___________ +1.17 +1.110.0200.0160.1181274814901141786.3918_hypotheticalprotein
192877___________ -1.12 -1.070.0650.0500.1941179910535110496.4386_pyruvatedecarboxylase
*194781___________ +1.83 +1.570.0010.0020.0051625029709255266.4891_
191396___________ -1.13 -1.100.0200.0680.0251178710445107216.5349_zincfingerprotein|putativeGTPaseactiovatingprotein
196374___________ -1.10 -1.190.0120.0510.0161771816117148476.5826_assemblyofmitochondrialF1F0ATPase
195085___________ -1.16 -1.130.0090.0270.016115749976102856.6290_
19540____________ -1.16 -1.130.0110.0310.018115469983102026.6752_palmitoyl-proteinthioesterase
193305___________ -1.20 -1.150.0060.0130.016115469633100036.7200_hypotheticalprotein
196509___________ -1.15 -1.140.0060.0220.0111206610451105886.7651_glutaredoxin
197197___________ -1.20 -1.180.0070.0160.01911682977099206.8097_nuclearexportofpre-ribosomes
197370___________ -1.18 -1.140.0110.0430.015115469778101076.8530_conservedhypotheticalmembraneprotein
197621___________ -1.12 -1.140.0180.0490.0271196410725104816.8969_EnhancedLevelofGenomicinstability,RepressorofTy1Transposition
19631____________ +1.05 -1.030.1540.4320.0945790861029563716.433__
196079___________ +1.27 +1.130.0090.0080.0681276016241143636.1065_hypotheticalprotein
194906___________ +1.27 +1.190.0080.0100.0381595520201189736.1617_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*191266___________ +2.36 +1.960.0000.0000.0003395080251664086.2158_
193169___________ +1.10 +1.060.0270.0200.1681436615824152166.2669_
194726___________ +1.12 +1.020.0820.0400.4732159924154221166.3188_calciumbindingprotein|regulatorofphosphatidylinositol-4-OHkinaseprotein
192399___________ +1.18 +1.140.0080.0120.0261289515257147306.3674_highlyconservedhypotheticalprotein
*191372___________ -1.84 -2.110.0000.0010.0005390829321255526.4158_
*195713___________ +1.35 +1.440.0020.0110.0031585421336228836.4643_NADHdehydrogenase
196235___________ +1.33 +1.170.0110.0110.0701630021739190316.5121_
191946___________ -1.15 -1.230.0030.0100.0082495521689203256.5592_
194934___________ +1.01 +1.010.6770.4070.9671235112433124456.6056_opaque-phase-specificproteinOP4precursor
196628___________ +1.09 -1.000.0890.0380.7991263613832125926.6525_spindlepolecomponent
*195158___________ -1.38 -1.620.0020.0140.0038037258090495496.6978_hypotheticalprotein
*194016___________ -3.58 -3.910.0000.0000.0004771081333141218746.7429_partofubiquinolcyt-creductasecomplex
194575___________ +1.01 -1.030.6900.4190.9641218212252118606.7875_
*195328___________ -1.35 -1.350.0000.0010.0005879043699436356.8317_
197498___________ +1.32 +1.260.0080.0120.0271414718714178636.8750_3-isopropylmalatedehydratase
194211___________ +1.28 +1.120.0070.0070.0641236615803138396.176__
192009___________ +1.25 +1.090.0220.0100.9321307516372142586.775__
192293___________ +1.32 +1.110.0050.0050.0641283516986142976.1365_
*194779___________ +1.58 +1.550.0010.0040.0051687826604261686.1908_multidrug-resistancetransporter
195071___________ +1.18 +1.110.0170.0150.0891253814797139586.2429_
19187____________ +1.07 +1.020.1620.0730.7331276413692129746.2959_
191167___________ +1.21 +1.180.0090.0140.0331280215512151506.3442_alpha-ketoglutaratecatabolismdioxygenase
196026___________ +1.09 +1.030.1580.0710.7321538016815157736.3930_C-8sterolisomerase
*193198___________ +1.96 +1.740.0010.0030.0031510629629263456.4402_
195725___________ +1.52 +1.340.0050.0090.0211259019152168886.4904_
192128___________ +1.00 +1.030.5270.2850.9511773317743183176.5362_putativeGTP-bindingprotein
193873___________ +1.10 +1.060.0610.0340.3411734119079183046.5844_componentoftheARP2-3complex
194400___________ +1.13 +1.080.0140.0180.0481445516345156416.6307_hypotheticalprotein
196659___________ -1.07 -1.100.0310.1290.0291594714903144626.6768_generalaminoacidpermease
193318___________ +1.13 +1.160.0120.0250.0261805920421209466.7213_conservedhypotheticalprotein
195277___________ +1.06 +1.020.1720.0810.6501310213927133976.7665_conservedhypotheticalprotein
197209___________ +1.16 +1.140.0040.0090.0121618918757184766.8109_rhoGDPdissociationinhibitor
*197382___________ -1.55 -1.490.0000.0010.0008092852054544496.8542_
197637___________ +1.25 +1.180.0080.0080.0501411417694166696.8985_flavohemoglobin
195530___________ -1.03 -1.000.9270.8030.8081255112215125316.453__
191753___________ +1.22 +1.090.0160.0140.1021246715152135876.1079_
193074___________ +1.02 +1.010.8620.7130.7444801048788484696.1631_
191143___________ +1.21 +1.150.0120.0150.0451250215162144036.2173_hypotheticalprotein
19240____________ +1.07 +1.040.3290.2430.4011185512644123286.2687_
194078___________ +1.04 -1.000.3650.1780.9051187812347118486.3202_3'-5exoribonucleaseinvolvedinribosomalRNAprocessing
195228___________ +1.09 +1.080.0350.0340.1091356814813146706.3689_3,4-dihydroxy-2-butanone4-phosphatesynthase,riboflavinbiosynthesis
195479___________ +1.07 -1.020.7280.4680.8671180212648115496.4172_
195498___________ +1.04 +1.000.3920.2160.6851276513216128246.4660_
193911___________ +1.00 +1.000.8530.6060.9351414514177141946.5137_S-adenosyl-L-homocysteinehydrolase
191842___________ +1.05 +1.050.2440.2070.2961216312808127456.5610_
194176___________ -1.01 +1.040.5960.5810.4451169711616121746.6070_mitochondrialribosomalproteinofthesmallsubunit
196642___________ +1.05 +1.000.1600.0680.9891310313773131306.6539_membraneproteininvolvedinvesiculartransport
*196843___________ +2.28 +1.740.0010.0020.0041383731556241156.6992_hypotheticalcoiled-coilprotein;possiblehistonebinding
194030___________ +1.08 +1.070.1150.0910.2311828819802196436.7443_p48polypeptideofDNAprimase
194590___________ +1.00 -1.010.4830.2530.9581214612168120506.7889_similartoDNA-bindingproteinbutmaybemissingDNA-bindingdomain
*195341___________ -1.30 -1.270.0060.0110.0183222124864253936.8330_ribosomalproteinS4
*197511___________ +1.72 +1.740.0000.0030.0014009269017697086.8763_largeyeastnucleoporin
194128___________ -1.08 -1.090.1180.2360.0971198511129110256.194__
191442___________ +1.44 +1.240.0040.0050.0241324119120164396.796__
192378___________ +1.23 +1.170.0160.0150.0761340416474156216.1381_putativeSMKkillertoxinresistanceprotein
193355___________ +1.17 +1.090.0090.0100.0471323915427144906.1924_
*192286___________ +1.24 +1.100.0170.0140.1082208827346242476.2446_phycocyaninalpha-subunitphycocyanobilinlyase
19609____________ -1.16 -1.110.0120.0260.0261163410023104556.2979_hypotheticalprotein
192922___________ +1.25 +1.080.0020.0020.1061271215896137556.3456_involvedinsynapsis
19909____________ +1.27 +1.240.0030.0060.0121740722145216186.3947_tRNAsplicing,uptakeofbranched-chainaminoacids
195580___________ +1.48 +1.290.0050.0070.0211430221211184336.4424_
191071___________ -1.14 -1.100.0140.0530.0191189710393107886.4918_hypotheticalprotein
192146___________ -1.18 -1.110.0120.0220.032117909994105756.5379_
193888___________ -1.06 -1.140.1380.9840.0651154610869101306.5859_phosphoglucoisomerase
194384___________ -1.20 -1.120.0200.0440.034116529722103926.6323_
196673___________ -1.15 -1.150.0050.0180.0081221810666106146.6782_beta-n-acetylglucosaminidase
19342____________ -1.16 -1.110.1620.0910.4471188010267106986.7226_hypotheticalprotein
195264___________ -1.11 -1.130.0130.0390.0211156610393102486.7678_hypotheticalprotein
197222___________ -1.21 -1.140.0050.0100.014117539721102976.8122_conservedhypotheticalprotein
197394___________ -1.18 -1.160.0080.0200.019117109929100856.8554_golgiguanosinediphosphatase
197654___________ -1.10 -1.130.0300.1140.0301214611038107306.9002_cyclophilinrelatedtothemammalianCyP-40
192026___________ +1.32 +1.170.0290.0230.1371285616983150496.472__
193735___________ +1.32 +1.150.0050.0060.0351277816846146666.1097_hypotheticalprotein
195580___________ +1.12 +1.060.0370.0230.2331224513713130336.1647_
19656____________ +1.10 +1.090.0160.0140.0961250713740136706.2191_diacylglycerolpyrophosphatephosphatase
192715___________ +1.16 +1.090.0310.0220.1681210814014132056.2704_RNApolymeraseIIIsubunit
191033___________ +1.10 +1.070.0560.0380.2211265113883135836.3218_cystathioninegamma-synthase|SulfurTRansfer
1993_____________ -1.22 -1.310.0230.0560.0342315919014176216.3705_
194494___________ +1.15 +1.100.0280.0260.1131222414075134276.4186_
192575___________ +1.25 +1.100.0470.0220.5341539419176169566.4676_highlyconservedhypotheticalprotein
19223____________ +1.10 +1.090.0670.0480.2211194213127129646.5151_
19332____________ +1.11 +1.100.0290.0330.0781410115634154556.5626_pre-mRNAsplicingfactor
192180___________ +1.06 -1.010.2330.1080.7831244613161123126.6083_calcium-bindingprotein
19663____________ +1.09 +1.030.1070.0460.7551215013239125306.6555_
196855___________ +1.01 +1.040.3960.2940.4401340813609138956.7004_conservedhypotheticalprotein
*192098___________ +2.23 +2.090.0000.0000.0003858485945804886.7457_aromaticaminoacidaminotransferase
194603___________ -1.02 -1.010.9300.9680.7391268612417125906.7902_GTP-bindingproteinoftheARFfamily|ADP-ribosylationfactor
195358___________ +1.12 +1.080.0330.0400.0791266214209136736.8348_
*197527___________ +1.19 +1.210.0050.0150.0102128425378257696.8777_
*19198____________ -1.31 -1.300.0010.0030.0015004638159383926.208__
*191179___________ -2.33 -2.440.0000.0000.0008424136186345896.819__hypotheticalprotein
192434___________ +1.50 +1.390.0030.0060.0121303319486181586.1397_
193494___________ +1.25 +1.180.0070.0100.0271291616174152156.1938_minichromosomemaintenance
*193604___________ +1.56 +1.520.0010.0040.0051763427427268046.2460_
*19792____________ +1.49 +1.470.0030.0050.0151567523373230246.2992_hypotheticalprotein
*191120___________ +1.86 +1.990.0000.0020.0011555428958308876.3472_hypotheticalprotein
191513___________ +1.17 +1.090.0230.0160.1601289415034140706.3963_
*195595___________ +1.85 +1.830.0000.0010.0012559947374468776.4436_
191057___________ -1.08 +1.030.7380.4800.8653570132915367486.4933_
*196175___________ +1.38 +1.580.0000.0010.0002361532614372136.5395_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*193136___________ +1.23 +1.360.0120.0520.0165385266009732676.5873_conservedhypotheticalprotein
195113___________ -1.26 -1.010.1500.0720.5883468272752413443256.6337_alcoholdehydrogenase
*196689___________ +1.45 +1.590.0000.0010.0012853441393452436.6798_argininosuccinatelyase
19355____________ +1.10 +1.120.0220.0340.0481278014110142796.7239_sulfonatedioxygenase
*195251___________ +1.11 +1.160.0340.0900.0402592628730301196.7690_
*197236___________ -2.14 -1.850.0000.0000.00012877960184696896.8136_translationinitiationfactoreIF3,p33subunit
*197409___________ +1.19 +1.360.0010.0060.0034854157843657926.8568_
*197667___________ +1.24 +1.550.0010.0110.0012348229215365136.9015_isoamylacetate-hydrolyzingesterase
6493_____________ +1.12 +1.080.0610.0480.1821259114164135406.493__
*19581____________ +2.54 +3.300.0000.0010.0012364159991779416.1111_
193163___________ +1.12 +1.090.0240.0250.0851467216395159716.1666_
195541___________ +1.09 +1.030.0780.0470.2991205513147124456.2206_
194430___________ +1.27 +1.210.0130.0240.0291241415715149756.2720_
193944___________ +1.06 +1.030.4920.2650.8701209012834124006.3230_
192794___________ +1.11 +1.050.0430.0290.2121273614176133396.3723_putativeracemase
192350___________ +1.17 +1.120.0190.0250.0591220914344137116.4203_
192733___________ +1.18 +1.080.0340.0320.1121249514799134866.4689_involvedinvacuolarproteinsortingandautophagy
*19207____________ +1.17 +1.300.0020.0210.0022033523872265216.5166_
19318____________ -1.33 -1.230.0070.0120.0262057715518167186.5640_
193427___________ +1.00 -1.020.7770.7620.5711270012717124936.6098_hypotheticalprotein
*19675____________ -1.82 -1.410.0000.0010.00513202572658934286.6568_hypotheticalprotein
191905___________ +1.44 +1.190.0050.0070.0291380019874163906.7015_phosphatidylinositol3-kinase
192087___________ +1.01 +1.010.6330.3740.8861250012668126206.7470_
*194617___________ +1.96 +1.780.0040.0060.0282125841693379136.7916_N-acetyltransferase
*197280___________ -4.11 -3.020.0020.0040.0084912211949162606.8361_hypotheticalprotein
*196337___________ -1.25 -1.250.0100.0530.01311322690832907266.8796_transcriptionalactivator
*1962_____________ +1.96 +1.730.0000.0010.0012032439897352566.22___zincaminopeptidase
191185___________ +1.09 -1.060.1690.1770.1993071333394288996.515__
*193778___________ +2.11 +2.350.0010.0020.0011874439564439886.1132_WD-repeatprotein
*194698___________ +3.56 +4.060.0000.0010.0011583356432642176.1685_serine/threoninephosphatasefamily2C
*193607___________ +2.31 +2.230.0010.0030.0051605137071358426.2220_
*194193___________ +1.28 +1.150.0060.0100.0201744622327201506.2742_cofilin/tropomyosin-typeactin-bindingprotein
195564___________ -1.14 -1.230.0100.0450.0131888616550153126.3247_ribonucleaseH,exon2
193080___________ +1.15 +1.080.0660.0730.1232428827884261206.3739_
194418___________ +1.19 +1.110.0070.0160.0181695820132188046.4221_methionyl-tRNAtransformylase
194652___________ -1.02 +1.000.9580.8140.9041263812445126656.4703_hypotheticalprotein
192411___________ +1.15 +1.090.0180.0190.0691410016221154136.5182_SNAREproteinreleatedtomammaliansyntaxin
*193978___________ +1.19 +1.300.0050.0160.0121556218443202286.5654_conservedhypotheticalprotein
192908___________ +1.13 +1.090.0390.0730.0561490516867161986.6114_conservedhypotheticalprotein
192766___________ +1.07 +1.010.5690.3580.6911280813650129686.6586_hypotheticalprotein
*191890___________ +1.60 +1.380.0010.0030.0103825661399527106.7030_conservedhypotheticalprotein
192071___________ +1.06 +1.040.4140.2760.5141205112740124786.7484_hypotheticalprotein
*197003___________ +1.77 +1.890.0010.0030.0022178238490411496.7929_hypotheticalprotein
197414___________ +1.09 +1.080.0800.0660.1871278213965137856.8375_
*196821___________ +1.32 +1.390.0060.0150.0141389418346193226.8810_subunitoftheAnaphasePromotingComplex
Cacht1___________ -1.13 -1.110.0380.0710.056116101027810456Cacht1_
*191338___________ +2.00 +1.920.0010.0020.0021575831500302816.226__
193556___________ +1.32 +1.230.0020.0040.0111288817014158566.836__karyopherinbeta2|transportin
*192623___________ +2.35 +2.190.0000.0000.0003369279055736996.1414_hypotheticalzincfingerprotein
191923___________ +1.18 +1.060.1090.0960.1986777379801719696.1956_
191982___________ -1.06 -1.050.3420.2620.3911812317124173346.2478_
191252___________ -1.03 -1.070.2870.6480.1584017639086374226.3007_mitochondrialproteinoftheCDC48/PAS1/SEC18familyofATPases
*194270___________ +1.60 +1.540.0000.0020.0021874130037288336.3487_manosyltransferase
*194772___________ +3.31 +2.740.0000.0000.0002365978390647616.3983_transmembraneosmosensor|involvedintheHOG1high-osmolaritysignaltransductionpathway
195513___________ -1.04 -1.040.4940.3310.5709176588499885246.4455_componentofthespliceosome
*195847___________ +1.52 +1.710.0000.0030.0012949944903504906.4949_DNA-directedRNApolymeraseIII
*196190___________ +1.50 +1.430.0010.0020.0051735792612042478056.5411_GDP-mannosepyrophosphorylase
192257___________ -1.03 +1.030.5370.3950.5364175440345432036.5889_hypotheticalprotein
*192007___________ +1.66 +1.550.0000.0010.0012635643874408376.6353_LossUpsetsVacuole
196703___________ +1.21 +1.180.0080.0130.0261806521940212506.6812_hypotheticalprotein
194443___________ -1.02 -1.110.2780.6790.1494982248922449756.7256_two-componentphosphorelayintermediate
*195238___________ -1.45 -1.470.0000.0010.0007320850469498016.7704_conservedhypotheticalprotein
197251___________ +1.15 +1.110.2110.2150.2286580075416733586.8151_cellwallintegrityandstressresponsecomponent4
*197422___________ +1.36 +1.440.0020.0070.0044505061401648736.8583_
196007___________ +1.07 +1.160.0540.6220.0282128722697246336.9030_similartofattyacidelongatingenzymes
*194954___________ -1.55 -1.220.0010.0020.0122026641304361661416.43___
*19749____________ +1.63 +1.510.0000.0010.0012439239878367176.534__hypotheticalprotein
191786___________ -1.04 -1.020.4850.4200.4203114430084305636.1155_
1914_____________ +1.01 +1.260.1420.8830.0682734412749863434686.1702_conservedhypotheticalprotein
*193352___________ +2.36 +1.930.0000.0000.0012225552467429806.2236_
*62757____________ +1.30 +1.350.0070.0220.0141504219483203176.2757_
194323___________ +1.32 +1.170.0020.0040.0151446019118168486.3263_conservedhypotheticalprotein
194908___________ +1.13 +1.100.0210.0180.1061338615128146676.3755_hypotheticalprotein
194899___________ +1.15 +1.110.0220.0280.0601613418562179146.4235_
19567____________ +1.19 +1.220.0050.0120.0111408516708172036.4717_
*194290___________ -1.07 +1.150.0400.0660.0653755034981433116.5196_thioredoxinreductase
196146___________ -1.00 +1.060.7220.4520.9274226442231450076.5669_
*192895___________ +1.35 +1.270.0010.0010.0042540034305322506.6127_vacuolarATPaseV1domainsubunitD
*194246___________ -1.39 -1.010.0110.0060.9829171665821905576.6599_
191876___________ -1.09 -1.070.0470.0410.1421809016540168686.7044_RNA-bindingprotein
*192059___________ +1.23 +1.200.0050.0130.0112166826546259076.7496_Endonuclease/Exonuclease/phosphatasefamily
*197018___________ -1.31 -1.220.0160.0130.1011366051041361120346.7944_ribosomalproteinS18B
197307___________ -1.16 -1.090.0350.0340.1092303019863210586.8388_conservedhypotheticalprotein
196807___________ -1.33 -1.480.0040.0100.0102547119146172346.8824_hypotheticalproteinsimilartoreversetranscripases
Cakre1___________ -1.00 +1.010.8740.6360.938118961185412056Cakre1_
*191769___________ +1.64 +1.530.0010.0020.0061464023964223726.245__
*191223___________ +1.95 +1.940.0000.0010.0021717233458332396.851__kinaserequiredforlatenucleardivision
*192630___________ +1.28 +1.290.0000.0010.0012323429667300856.1435_involvedinmitoticrecombinationandDNArepair
191946___________ +1.14 +1.150.0040.0090.0101953222348224316.1972_conservedhypotheticalprotein
*194072___________ +1.48 +1.560.0020.0050.0041589223477248496.2492_
*193222___________ +1.47 +1.390.0000.0020.0012071430366287346.3022_
195190___________ +1.06 +1.020.8760.9740.6502345424956238656.3501_hypotheticalprotein
*192936___________ +1.47 +1.360.0010.0020.0021890427815256636.4000_hypotheticalprotein
195526___________ +1.06 -1.000.3130.2970.2981878019888187426.4468_secretorypathwayprotein
*192471___________ +1.26 +1.400.0000.0030.0012638533280368106.4964_subunitoftubulinprefoldin
*196197___________ +1.95 +2.170.0000.0000.0002766053884600176.5427_RNAhelicaseofDEADboxfamily
194924___________ +1.12 +1.070.0170.0140.1181257414135134986.5904_splicingfactor3b
*191991___________ +1.22 +1.320.0040.0130.0081775821597233956.6368_
*194107___________ +1.11 +1.240.0110.0890.0113268336162404096.6829_exopolyphosphatase
*194456___________ +3.79 +4.570.0000.0000.000398581511091822976.7269_aminoacidpermease

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
196972___________ +1.04 +1.120.0840.1600.0841845919214206536.7718_involvedin(1,3)-beta-glucansynthesis
197266___________ -1.11 -1.130.0290.0690.0401643314856145006.8166_hypotheticalprotein
*197437___________ -1.18 +1.000.0400.0170.7895034142537504286.8597_maltoseacetyltransferase
195992___________ +1.06 +1.070.0870.1220.1091524916210162756.9045_zincfingertranscriptionfactor
19149____________ +1.20 +1.170.0150.0200.0481300015574152066.62___hypotheticalprotein
*19787____________ +1.35 +1.220.0080.0140.0262487633620302436.558__hypotheticalprotein
191524___________ +1.20 +1.150.0160.0180.0621217814645140276.1173_
195574___________ +1.24 +1.120.0120.0110.0781222715197136486.1721_conservedhypotheticalprotein
*194369___________ +1.81 +1.500.0010.0020.0072214840190331576.2255_phosphophorynprecursor
*191306___________ +1.64 +1.440.0010.0020.0051721628309247966.2774_conservedoxidase
*192850___________ +2.16 +1.820.0000.0010.0013133467579569856.3280_hypotheticalprotein
193466___________ +1.16 +1.090.0760.0390.4411263314687137136.3769_SAM-dependentmethyltransferase
*191837___________ +1.98 +1.780.0000.0000.0015040999854897226.4248_
193344___________ +1.04 -1.080.4470.3340.4673470436178322706.4735_vacuolarsortingprotein
194804___________ +1.09 +1.050.0660.0370.3341222513339128116.5210_secretorylipase
19598____________ +1.16 +1.070.0530.0400.1801319615313140986.5682_hypotheticalprotein
195838___________ +1.04 +1.000.4110.2070.9031422014853142476.6140_phosphoserinephosphatase
*194232___________ +1.29 +1.140.0070.0080.0482071626753235546.6613_prolinetransporthelper
*19510____________ +2.94 +2.350.0000.0000.0002771081447651346.7061_
193817___________ -1.00 -1.060.5880.8360.3572517425054237136.7512_similartomouseKIN7protein
*197030___________ +1.90 +2.160.0010.0030.0023588268267774916.7957_
197320___________ +1.11 +1.050.4100.2180.7561608417781168326.8401_secretorylipase7
*196794___________ -2.13 -2.760.0000.0000.00016484277392597036.8837_NADH-ubiquinoneoxidoreductase
42986____________ +1.10 +1.100.0630.0810.1011307014375143984.2986_
*193803___________ +8.90 +9.230.0000.0000.000202961805641873536.264__
191227___________ +1.20 +1.120.0070.0080.0411350816146150886.867__hypotheticalprotein
*194918___________ +1.79 +1.480.0000.0010.0032392542841354996.1451_
*19252____________ +1.35 +1.260.0070.0090.0431357618357170736.1988_
19104____________ +1.19 +1.200.0140.0200.0431426616977171146.2507_hypotheticalprotein
191697___________ +1.07 +1.050.1360.0990.2751893220331198246.3037_
194707___________ +1.36 +1.290.0020.0050.0091290817534166606.3513_
*19695____________ +1.66 +1.610.0010.0040.0051593626523257136.4013_hypotheticalprotein
193186___________ +1.19 +1.170.0050.0090.0171342815974156996.4483_hypotheticalprotein
*193482___________ +1.83 +1.830.0000.0000.0005166594667945066.4977_hydrolyzesthepyrophosphatelinkageinNADHandrelatednucleotides|NADHpyrophosphatase
196291___________ +1.32 +1.190.0050.0090.0191355717873160966.5440_
1926_____________ +1.09 +1.040.1330.1250.1982012222025209026.5920_peptide-N4-(N-acetyl-beta-glucosaminyl)asparagineamidase
*191418___________ +1.11 +1.060.0350.0390.0904650651628494486.6387_exocystcomplexcomponent
*194093___________ +1.34 +1.390.0140.0350.026811401089851124786.6843_pescadillohomolog|nucleolarproteinrequiredforrRNAprocessing
19895____________ -1.03 -1.040.5700.3800.6335306851750511066.7282_mitogen-activatedSer-Thrproteinkinase|osmoregulation
*196984___________ +1.43 +1.580.0020.0080.0041599722844252816.7730_transmembraneaminoacidtransporterprotein
*19931____________ +1.65 +1.540.0000.0010.0022187836194337146.8180_hypotheticalprotein
*197450___________ +1.58 +1.450.0010.0030.0022509839565365056.8610_maylocalizetomother-budneckinaseptin-dependentmanner|similartomammalianhomerporteins
195978___________ +1.10 +1.090.0440.0550.0861413615508154606.9058_
192552___________ +1.18 +1.130.1110.1560.1241302015378147336.87___
194354___________ +1.25 +1.120.0060.0070.0381283616064143236.577__
191817___________ +1.20 +1.170.2030.5300.1161341516111156776.1192_hypotheticalprotein
194261___________ +1.18 +1.150.0060.0090.0231302015420150136.1735_
196254___________ +1.12 +1.060.0690.0490.2211549017373163656.2269_ADP/ATPcarrierprotein
194337___________ +1.26 +1.150.0030.0040.0261376117377158166.2794_monocarboxylatepermease
194916___________ +1.05 +1.000.3510.7380.1912505826377251786.3294_
192930___________ +1.05 -1.000.8350.5810.9431751018472174566.3787_
*192216___________ +1.79 +1.800.0000.0010.0011838632874331316.4261_PrecociousDissociationofSisterchromatids|chromosomedynamics
*192110___________ +1.25 +1.300.0030.0080.0092613532640340156.4751_arginyltRNAtransferase
194153___________ +1.06 +1.090.0430.0460.1051337014235145856.5225_involvedinproteinmodification|requiredforactivationofRUB1(ubiquitin-likeprotein)
192989___________ +1.06 +1.090.4490.2360.8371288613656140236.5700_
*195825___________ +1.31 +1.260.0010.0050.0032696735267340316.6153_transcriptionalrepressor
195796___________ +1.12 +1.160.0130.0370.0221497816760173606.6629_
19496____________ +1.02 +1.070.2240.2800.1951639916749175516.7076_
193833___________ +1.13 +1.090.0240.0190.1301431716241155696.7527_
*197044___________ +2.56 +3.060.0000.0010.0002066452877632076.7971_
197332___________ +1.09 +1.040.0620.0390.2711268613878131386.8414_
196782___________ -1.00 +1.060.2740.4420.1831490414855158076.8849_hypotheticalprotein
*42119____________ +1.55 +1.570.0020.0080.0051546224017242754.2119_
194513___________ +1.21 +1.170.0030.0050.0171250015141145796.279__
*19778____________ +1.37 +1.290.0030.0060.0121459020002188846.892__
192660___________ +1.18 +1.130.0110.0150.0421328415643150126.1465_Esa1p-AssociatedFactor|cellpolarityprotein
191679___________ +1.22 +1.120.0030.0040.0261295615744144626.2001_hypotheticalprotein
191780___________ +1.11 +1.100.0110.0110.0691254813890138316.2527_conservedhypotheticalprotein
194886___________ +1.05 +1.050.1480.0880.3921325513937138566.3052_hypotheticalprotein
19652____________ +1.25 +1.120.0060.0060.0431295916233145216.3530_
195375___________ +1.08 +1.080.0380.0320.1351239913376133846.4029_conservedhypotheticalprotein
192836___________ +1.09 +1.030.1860.0940.5701942721089199306.4497_conservedhypotheticalprotein
*194521___________ +1.44 +1.390.0000.0010.0012395234511333616.4990_weaksimilaritytoreductases
194680___________ +1.22 +1.170.0040.0050.0391605019564188166.5456_lowhomologytosphingosinekinase
19201____________ +1.10 +1.070.0330.0280.1271329314598142076.5934_DNAhelicaseandDNAreplicationlicensingfactor
191543___________ +1.04 +1.040.2770.1780.4401548016077161516.6401_hypotheticalprotein
194081___________ +1.01 +1.020.8980.8840.7011460114782148426.6855_hypotheticalprotein
*19879____________ +1.06 +1.150.0210.2590.0142439125854280906.7298_requiredformothercell-specificgeneexpression
196996___________ +1.03 +1.040.2530.1480.4861169912047121336.7742_alpha-1,3-mannosyltransferaseinvolvedinaddingthe4thand5thmannoseresiduesofO-linkedglycans
19944____________ -1.02 -1.020.8180.9840.5701596215714155856.8193_DAO,FADdependentoxidoreductase|d-aminoacidoxidase
195387___________ +1.03 +1.150.0490.0820.0701509715532173606.8622_
195966___________ +1.03 -1.000.3790.1870.9061288013277128316.9071_hypotheticalprotein
*193997___________ -1.43 -1.800.0010.0280.00113222939225217349126.106__
*19542____________ +2.57 +1.940.0000.0000.0001090132803292113886.598__
*192023___________ +14.89 +12.140.0000.0000.000656219772347964766.1210_
194701___________ +1.14 +1.120.0200.0200.0871271414462141796.1754_
*193770___________ +1.52 +1.540.0020.0060.0061433021741221026.2287_
19406____________ +1.09 +1.070.0180.0260.0461928721061205506.2816_squaleneepoxidase(monooxygenase),erosterolbiosynthesis
193653___________ +1.33 +1.350.0030.0120.0071289917133174556.3308_verylong-chainfattyacyl-CoAsynthetase
195716___________ +1.26 +1.260.0030.0080.0091333816871168536.3803_candidapepsin4precursor
*192609___________ +3.04 +2.540.0000.0000.0002740483248696546.4276_RNA5'-triphosphatase(mRNAcappingenzyme,betasubunit)
192368___________ +1.22 +1.300.0120.0270.0231341216405174366.4766_chromatincomponent
*193854___________ +1.35 +1.570.0020.0110.0041644822204258826.5245_
192975___________ +1.18 +1.090.0090.0080.0701469817402160146.5714_GTP-bindingprotein
*192485___________ +1.31 +1.190.0130.0330.0231496019627177436.6167_
*195811___________ -1.30 -1.340.0000.0010.0004218532423315426.6644_
19481____________ +1.14 -1.020.1770.0960.4865482262764538686.7090_translationinitiationfactoreIF2Bsubunit
196557___________ +1.12 +1.080.3770.1890.8451351815143146386.7545_putativeamidase
195025___________ -1.34 -1.090.1830.0970.5145470440951501486.7984_ATPsulfurylase,Aminoacidmetabolism
*197125___________ +1.20 +1.110.0390.0440.0943204438313357206.8428_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
196769___________ +1.09 +1.120.0240.0960.0261620217719181476.8863_
42513____________ +1.08 +1.030.1080.0580.4292105722647217604.2513_
191295___________ +1.01 -1.100.2260.5710.1274951450106451376.295__
*191949___________ +2.97 +3.070.0000.0010.0011857055070569586.919__
*193174___________ +1.39 +1.230.0010.0020.0103940654869483256.1482_
*191748___________ +1.51 +1.480.0020.0040.0061565623598232426.2022_
194767___________ +1.46 +1.340.0010.0020.0031732225372232186.2541_zincfingerprotein
*193793___________ +1.33 +1.270.0040.0070.0171448219248183426.3066_hypotheticalprotein
*19863____________ -1.71 -1.730.0000.0010.0014317625278249296.3551_ribosomalproteinofthelargesubunit,mitochondrial
*195815___________ +1.38 +1.360.0020.0060.0071806425004246116.4044_glycerol-3-phosphateacyltransferase
*195643___________ +1.20 +1.230.0020.0060.0053196838517394576.4512_conservedhypotheticalprotein
*194507___________ +1.23 +1.100.0300.0200.2031522818732168236.5004_leucinerichrepeatgenefamilyprotein
*193740___________ +1.13 +1.190.0060.0470.0082900432720344916.5470_
195147___________ +1.35 +1.250.0080.0090.0451269617120158326.5951_
191557___________ +1.16 +1.110.0110.0170.0341503217412166276.6414_
*196720___________ +1.15 +1.140.0100.0150.0302868533121327416.6869_conservedhypotheticalprotein
*196925___________ +8.27 +7.120.0000.0000.00012185510078938678306.7311_histoneH2B
193019___________ +1.22 +1.270.0430.2690.0291353016574172226.7757_
19956____________ +1.29 +1.200.0070.0090.0361502019376180826.8208_
*195402___________ +1.52 +1.780.0010.0050.0021940529489346126.8638_hypotheticalprotein
195952___________ -1.02 -1.020.5830.5920.4241605115730157826.9085_hypotheticalprotein
194167___________ +1.53 +1.390.0010.0030.0041389921314193186.125__hypotheticalprotein
*191018___________ +1.16 +1.090.0220.0170.1293145336448341836.620__
*192706___________ +1.31 +1.350.0010.0070.00275871994881024666.1230_
*192839___________ +2.43 +2.170.0000.0000.0012522361325547016.1773_
191541___________ +1.13 +1.090.0220.0160.1461224013880133546.2304_
194459___________ +1.44 +1.240.0050.0090.0191297218648160236.2833_weaklysimiulartotomammalianglobins
*195045___________ +2.58 +3.110.0000.0010.0002268458522706036.3322_proteintyrosinephosphatase
*192644___________ -2.41 -2.420.0000.0000.00013976257881577886.3819_ubiquinol--cytochrome-creductase40KDchainII
*193544___________ +1.16 +1.190.0040.0120.0082595330047308026.4290_quinoneoxidoreductase
64782____________ +1.06 +1.110.2700.8020.1373955741954440606.4782_
*196554___________ +1.96 +1.830.0000.0000.0012255744275412916.5260_conservedhypotheticalprotein
191260___________ +1.32 +1.290.0030.0050.0111568720646202066.5727_similartohumanU2AsnRNPprotein
*192501___________ +1.48 +1.550.0030.0080.0091439821288223036.6182_
*192958___________ +2.35 +2.520.0000.0020.0011683039589424806.6658_conservedhypotheticalprotein
*191467___________ -2.96 -2.920.0000.0000.00018998064095651286.7106_cytochromecoxidasesubunitVIa
196573___________ +1.18 +1.130.0230.0180.1351262414863142766.7560_
195012___________ +1.08 +1.050.3160.1990.4841735018764182426.7997_hypotheticalprotein
197112___________ +1.05 +1.020.2590.1530.4891545416290157156.8441_transmembranesubunitofferricreductase
*196755___________ +1.21 +1.430.0010.0080.0021536018564219146.8876_mitochondriallactateferricytochromecoxidoreductase
42737____________ -1.02 +1.010.8190.5640.9261220411958123094.2737_
195143___________ -1.28 -1.360.0040.0130.0082833722118207916.312__mitochondrialinnermembranetranslocase
191494___________ +1.02 -1.010.9380.8740.7862513925656249576.935__nucleotideexcisionrepairprotein(ubiquitin-likeprotein)
*193530___________ +1.25 +1.420.0030.0100.0082708133748383636.1500_caseinkinaseIIalphasubunit
*193524___________ +1.75 +1.990.0000.0020.0011858832619370736.2037_cdc2-relatedproteinkinase
193783___________ +1.14 +1.200.0020.0060.0071827720907219346.2555_hypotheticalprotein
191217___________ -1.04 +1.020.5440.3350.6952931028243298696.3081_
*192275___________ -2.73 -2.740.0000.0000.0006835725021249666.3566_60SribosomalproteinL7/L12
*193919___________ -1.39 -1.390.0010.0030.0054278830698308576.4058_
*196219___________ -1.47 -1.390.0010.0020.0023024320539216986.4531_conservedhypotheticalprotein
*194201___________ +1.08 +1.190.0180.1020.0185713061769679646.5020_NA+/H+antiporter
*192695___________ +1.29 +1.470.0000.0040.001847171096841247786.5483_ubiquitin-proteinligase
*195134___________ +1.31 +1.440.0010.0060.0021463619119210216.5964_hypotheticalprotein
191571___________ -1.00 +1.010.5650.3430.7311366213614137356.6428_
*196734___________ +1.19 +1.290.0070.0330.0103703643999478806.6884_
196940___________ +1.03 +1.090.0480.1530.0431936819904211306.7326_hypotheticalprotein
193034___________ +1.00 +1.030.5530.6140.3822207022151228286.7769_
19972____________ +1.12 +1.100.0190.0350.0391543717324170126.8221_conservedhypotheticalprotein
*195416___________ +1.51 +1.640.0040.0060.0252034030793333006.8651_
195938___________ +1.03 +1.000.2780.1300.8281270613135127146.9101_
*193373___________ +1.20 +1.090.0120.0100.1062113425270231306.141__
*191026___________ +1.36 +1.350.0020.0070.0072174829596293506.647__exosome3'->5exonuclease|involvedinkinetochore-relatedfunction
*192452___________ +1.96 +1.860.0010.0020.0021507329607280676.1246_
*192914___________ +1.50 +1.320.0010.0020.0092574438668339796.1790_hypotheticalprotein
*191037___________ +1.60 +1.680.0010.0020.0031861329828312256.2320_hypotheticalprotein
191193___________ +1.27 +1.240.0020.0080.0061523019315188456.2847_
*194892___________ +1.36 +1.270.0010.0030.0032433633036310276.3336_
*194875___________ +1.52 +1.510.0010.0030.0021891628766284756.3834_conservedhypotheticalprotein
194481___________ +1.16 +1.110.0150.0200.0461295515056144456.4306_hypotheticalprotein
*192690___________ +1.31 +1.120.0110.0090.1114247855775476486.4800_mitochondrialdynamin-likeGTP-ase
*196541___________ -1.60 -1.790.0000.0010.00010518465717586436.5273_ribosomalproteinL5
*191664___________ -1.09 -1.100.0340.2600.0232811025835255516.5739_beta-glucosidase
*196589___________ +1.29 +1.190.0130.0250.0312374630586283266.6201_ribosomallargesubunitassemblyandmaintenance
192945___________ +1.18 +1.200.0100.0230.0201531818090183926.6671_prolinepermease
*191453___________ +1.41 +1.340.0030.0050.0254163758615557076.7119_
196586___________ -1.00 +1.000.9270.7790.8371339613335134196.7574_conservedhypotheticalprotein
*194997___________ +2.19 +2.450.0020.0050.0051620335445397286.8012_FOG1protein
*197100___________ +1.52 +1.390.0010.0030.0052002830409278566.8454_
196741___________ +1.26 +1.230.0180.0320.0381432918010175546.8890_consevedhypotheticalprotein
42841____________ +1.04 +1.040.1310.0880.3041211012650126234.2841_
*194705___________ +1.93 +1.780.0010.0020.0031710032934303776.327__
19234____________ +1.14 +1.130.0170.0160.0851576717898177666.953__
*193623___________ +2.37 +2.390.0000.0010.0011789642442428136.1515_chromosomesegregationandcondensation
*194630___________ +1.67 +1.540.0000.0020.0012451940847377026.2053_carbamoylphosphatesynthetase,argininespecific
*193363___________ +4.07 +4.400.0000.0000.0001656267459728556.2574_
194560___________ +1.16 +1.060.0230.0160.1701441816714153336.3094_
*192751___________ +2.20 +2.090.0000.0010.0011592835062332626.3583_monocarboxylatepermease
194664___________ +1.32 +1.290.0040.0090.0131389918284179846.4072_
*194379___________ -1.11 +1.280.0120.5880.0077304665998934846.4545_
*193323___________ +1.14 +1.180.0050.0250.0072529028777298806.5031_hypotheticalprotein
196310___________ +1.28 +1.200.0040.0080.0151622720787194136.5503_conservedhypotheticalprotein
*192039___________ -2.40 -2.660.0000.0000.0007643431887287186.5978_phenylalanyl-tRNAsynthetasealphasubunit,mitochondrial
*191631___________ +2.32 +2.240.0000.0000.0003279476214735146.6441_S-adenosyl-methioninedelta-24-sterol-c-methyltransferase
195658___________ -1.12 -1.100.1680.1340.2675845852347533816.6898_galactosyltransferase
*196955___________ +1.34 +1.430.0010.0070.0023289943958469196.7341_Nin1(One)Bindingprotein
*193047___________ +1.35 +1.400.0060.0170.0141548620844216756.7783_
*193235___________ +1.59 +1.460.0010.0020.0031829229108266166.8235_capping-additionofactinsubunits
195429___________ +1.09 +1.030.0500.0310.2611321714413135666.8665_conservedhypotheticalprotein
195924___________ -1.00 -1.030.9830.8840.9313105830964301366.9114_
*192671___________ +1.07 +1.290.0040.1440.0033384036342436626.154__

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
19151____________ +1.20 +1.110.0080.0080.0731324215918147006.662__aminoacidpermease
191906___________ +1.28 +1.250.0030.0080.0081665521284207416.1265_hypotheticalprotein
*193392___________ -1.25 -1.350.0010.0060.0023719029768276396.1809_2-deoxyglucose-6-phosphatephosphatase
*191643___________ -2.37 -2.050.0000.0010.0024712619924229506.2338_
195856___________ +1.12 +1.100.0170.0220.0531295214571142576.2864_
192652___________ +1.11 +1.090.0160.0170.0651267514086138526.3351_similartotranslationelongationfactoreEF1,gammachain
*19837____________ +1.31 +1.270.0020.0040.0061900824811241876.3848_glucosamine-phosphateN-acetyltransferase
194467___________ -1.06 -1.090.1670.3610.1142944227765270946.4319_
19287____________ +1.03 +1.010.4990.2650.9351508415526152416.4816_NADH-ubiquinoneoxidoreductasesubunit
193003___________ +1.16 +1.140.5440.7500.3351654701925441884486.5286_hypotheticalprotein
*193577___________ -2.14 -1.990.0000.0000.0007009232763352586.5752_mitochondrialC-methyltransferase|co-enzymeQdeficient
196604___________ +1.04 +1.100.0450.0470.1091242012954136766.6215_
*194537___________ +1.32 +1.420.0000.0010.0013512546201499796.6683_transcriptionalelongationfactor(TFIIS)
*196869___________ +1.42 +2.040.0000.0000.0002910541223593586.7133_mitochondrialinnermembraneprotease|involvedintargetingofplasmamembrane[H+]ATPase
196043___________ +1.05 +1.050.1260.1060.2211273013418134016.7586_
197127___________ -1.13 -1.180.3240.5100.207117562104146999806.8027_
*197085___________ -2.21 -1.760.0000.0010.0032862751296071629676.8468_hypotheticalprotein
197555___________ +1.01 +1.040.2240.3960.1531548515645160276.8903_hypotheticalprotein
42938____________ +1.07 +1.080.1180.1550.1361370914694148464.2938_
*191738___________ +1.88 +2.230.0000.0000.0003507465943780476.346__
195596___________ +1.22 +1.160.0060.0080.0321303215925151396.971__
*191083___________ +1.19 +1.260.0010.0080.0032360928140296766.1532_conservedhypotheticalprotein
*191388___________ +1.28 +1.430.0010.0050.0021979825412283176.2076_nucleolarproteininvolvedinribosomebiogenesis
*193778___________ +1.42 +1.730.0000.0010.0002588236806447536.2592_
*194275___________ +1.45 +1.490.0090.0110.0451714324843254686.3111_responsivetoDNAdamage
*192604___________ +1.20 +1.230.0040.0110.0122130925509261436.3596_
*191763___________ +1.86 +2.070.0000.0000.0001638130503339836.4086_putativereductase/dehydrogenase
*195680___________ +1.48 +1.470.0000.0020.0012023729971298446.4558_hypotheticalprotein
195854___________ -1.01 +1.150.2330.9920.11498884982481135316.5046_singlestrandednucleicacidbindingprotein
*196323___________ +1.82 +1.350.0000.0000.0042782850762374426.5516_histoneandotherproteinacetyltransferase
192051___________ +1.04 +1.030.1890.0920.6291404814678144196.5991_
*193447___________ +1.88 +2.260.0000.0000.0001707332154386416.6458_requiredforpost-translationalprocessingoftheproteaseBprecursorPrb1p
*195672___________ +8.58 -1.990.0000.0000.00229610254108148866.6912_ammoniapermease
*194851___________ +1.44 +1.530.0010.0030.0012089430126320056.7359_
*193059___________ +1.22 +1.250.0030.0050.0213559243565444296.7796_generalRNApolymeraseIItranscriptionfactor,TFIIBsubunit
193248___________ +1.17 +1.160.0050.0070.0221546618051179256.8248_nucleardistributionproteinNUDE
*195442___________ +1.42 +1.460.0010.0020.0021697224018247426.8678_conservedhypotheticalprotein
195910___________ +1.05 -1.000.3210.7150.1741309213785130516.9127_zincfingerprotein|HATcomplexcomponent
*19216____________ +1.49 +1.460.0030.0070.0101515322528221716.28___
192158___________ +1.06 -1.050.1880.1510.2812469626228235606.682__
191984___________ +1.14 +1.120.0620.0480.1871323515098148796.1283_conservedhypotheticalprotein
*191750___________ +1.77 +1.480.0000.0000.002851781504611256446.1826_
192542___________ -1.02 -1.030.2310.1140.6582161721198209006.2352_
194484___________ +1.23 +1.230.0050.0150.0121597319615196136.2883_hypotheticalprotein
192528___________ +1.24 +1.230.0150.0190.0521485218446183316.3369_TFIIIBsubunit
192385___________ +1.12 +1.010.0570.0280.4392622029314265876.3863_RNApolymeraseIIElongatorassociatedprotein
193396___________ -1.03 -1.030.6010.6260.4261716816693166796.4335_highcopyHsp90supressor
19599____________ +1.01 -1.000.7300.4640.9031234612468123396.4832_
191366___________ +1.07 +1.010.0960.0440.5971476215729149186.5298_flavonolsynthase
*193561___________ +1.50 +1.510.0020.0040.0071518822758229946.5768_serine/threoninekinaseinvolvedinmitosis
196110___________ +1.03 +1.030.2190.2280.2271353313888139616.6231_hypotheticalprotein
*19808____________ +1.43 +1.330.0010.0040.0043018343247400996.6698_
*196883___________ +1.90 +1.690.0000.0000.0013638069185613856.7147_oxysterol-bindingproteinimplicatedinergosterolbiosynthesisandregulationofGolgi-derivedtransportvesiclebiogenesis
*196056___________ +1.52 +1.400.0010.0020.0042201633481307436.7600_conservedhypotheticalprotein
*197144___________ +1.11 +1.110.0170.0190.0622425026859269236.8043_
197072___________ -1.03 -1.050.4240.6660.2521213811741115426.8481_phosphatidylglycerolphosphatesynthase
197568___________ +1.05 +1.050.0970.1120.1381290513533135386.8916_sporulation-specificprotein
43081____________ -1.05 -1.040.2800.4400.1881176511186112744.3081_
*192534___________ +1.33 +1.440.0000.0010.0014371758071627726.364__
*19600____________ +1.37 +1.690.0040.0140.0081334918224225566.993__
195532___________ +1.49 +1.490.0010.0020.0041481422034221446.1547_hypotheticalprotein
*195748___________ -1.47 -1.820.0050.0160.0103257222116179036.2093_
*194134___________ +1.61 +1.740.0010.0030.0031396922430243486.2613_zincfingerprotein
*191152___________ -2.06 -1.910.0010.0010.00316922682256884586.3127_hypotheticalprotein
*192792___________ +2.61 +2.570.0010.0030.0021668443525428346.3611_
192597___________ +1.33 +1.340.0020.0060.0041595321187213406.4102_
*195693___________ +1.12 +1.180.0110.0330.0193027434043356076.4573_
*195867___________ +2.51 +2.550.0000.0010.0012092452505532716.5059_
*192315___________ +1.87 +1.950.0000.0020.0012397944916466606.5534_
*193703___________ +1.22 +1.250.0010.0040.0043548743211443546.6006_hypotheticalprotein
*193435___________ +1.57 +1.320.0000.0010.0042864845089377696.6470_hypotheticalprotein
193121___________ -1.05 +1.010.7870.5240.9241474813985149656.6924_nitrogencataboliterepressionregulator,inhibitorofGln3
*194836___________ -1.28 -1.550.0010.0110.002128508100042827086.7375_dihydroorotateoxidase
*196447___________ -1.36 -1.570.0020.0110.005148634108970945166.7808_
*68262____________ +1.92 +1.530.0000.0000.0012950256724451346.8262_
*195454___________ +10.89 +8.860.0000.0000.000184582010671635506.8692_
195894___________ +1.03 +1.020.5600.3080.9681285913262130756.9142_
*193110___________ +1.51 +1.350.0010.0020.0041694025510229456.61___
*6701_____________ +1.30 +1.220.0010.0010.0052268029515277506.701__
*195544___________ +2.58 +2.510.0000.0000.0002517164839631356.1298_
*194346___________ +1.40 +1.270.0040.0080.0175784180867733766.1846_
*194639___________ +1.12 +1.140.0290.0490.0544306648020492596.2370_conservedproteinwithputativeprotein-disulfideisomerasedomain
*191277___________ +2.57 +2.520.0000.0010.0012380861305600196.2900_hypotheticalprotein
195054___________ -1.03 -1.050.3090.4020.2272357622854224996.3382_BiosynthesisofNicotinicAcid
*193687___________ +1.43 +1.500.0000.0010.0012476335343371646.3879_prefoldinsubunit1,componentofachaperone
*192193___________ +1.40 +1.350.0010.0030.0041801725238243796.4348_phosphoribosylpyrophosphatesynthetase
191715___________ +1.27 +1.160.0050.0050.0391349017114157006.4845_transcriptionfactor
*193714___________ +2.30 +2.660.0000.0010.0001958444993520816.5312_hypotheticalprotein
*196353___________ +1.06 +1.110.0220.0550.0322190923195242606.5782_leucine-richrepeatprotein
*196096___________ -2.53 -2.480.0000.0000.00021647285426873286.6245_phosphoribosylanthranilateisomerase
*19822____________ -9.33 -13.510.0000.0000.00076110281555563556.6713_hypotheticalprotein
*196899___________ -2.91 -3.260.0000.0020.0015672619500174016.7163_oxidoreductase|quinicacidutilization
*196068___________ +1.74 +1.660.0000.0000.0005563296543921086.7612_involvedindiauxicshift
197158___________ +1.15 +1.200.0040.0090.0141821920934218436.8058_memberofallantoatepermeasefamily
197059___________ -1.01 -1.010.9070.9980.6961555215422154026.8494_conservedhypotheticalprotein
*197583___________ +1.11 +1.410.0010.1800.0015786664477817066.8931_potentialfungalZn(2)-Cys(6)binuclearclusterdomain
19615____________ +1.40 +1.190.1480.1450.2001228617199145906.380__hypotheticalprotein
*19773____________ +1.55 +1.590.0010.0030.0021705326402271096.1014_
192926___________ +1.36 +1.380.0020.0080.0041553621167215066.1562_interstrandcrosslinkrepairprotein
191482___________ +1.10 +1.130.1590.3200.1153378637159380376.2106_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194980___________ +1.14 +1.110.0880.0470.4121358015446150596.2627_heatshockprotein70
194975___________ +1.20 +1.130.0150.0200.0511391216758156846.3142_
195541___________ +1.24 +1.240.0180.0240.0551423817719176836.3626_
195548___________ +1.44 +1.330.0020.0050.0091330119172177556.4118_
192804___________ +1.30 +1.150.0060.0060.0601397418140160706.4589_
*195597___________ +1.85 +1.950.0000.0010.0002010437132392806.5074_
192302___________ -1.09 -1.060.0820.0410.4674891844738459796.5548_conservedhypotheticalprotein
19725____________ +1.12 +1.040.1360.0710.4791269214260131626.6018_hypotheticalprotein
*193673___________ +1.26 +1.350.0010.0050.0022666933637358746.6484_Golgivesicledocking(TRAPP)
193107___________ +1.26 +1.300.0030.0090.0081461618445189536.6938_hypotheticalprotein
*194823___________ +1.06 +1.120.0410.4730.0233344035311373406.7388_secretorylipase
196431___________ +1.12 +1.030.0470.0230.4401236013871127656.7824_
*193275___________ -1.15 -1.040.0240.0130.3243848433359369206.8275_hypotheticalprotein
195472___________ +1.02 -1.020.9190.8830.7392384324202234446.8708_hypotheticalprotein
195880___________ +1.11 +1.120.0220.0440.0401408815593157316.9157_voltage-gatedchloridechannel
191747___________ +1.04 +1.070.1560.1940.1621203112498129336.86___
194142___________ +1.25 +1.250.0110.0150.0401431017924178786.717__
192164___________ +1.27 +1.220.0050.0070.0351442418384176626.1312_reversetranscriptase(incomplete)
*191974___________ -2.00 -2.510.0000.0000.000226514113142903646.1861_carboxypeptidaseYinhibitor
*192534___________ +1.33 +1.160.0010.0020.0183213442725373816.2383_
193796___________ +1.20 +1.160.0080.0130.0261806621661210176.2913_
*191514___________ +1.15 -1.070.0360.0170.4784759754894445226.3399_
*19422____________ +1.49 +1.610.0010.0040.0031789126742287216.3893_
193501___________ +1.23 +1.220.0200.0270.0551569219261191776.4360_
*195788___________ -1.63 -2.130.0000.0010.0006146003780372888716.4859_
196164___________ +1.05 +1.020.1530.0820.4621283313524131386.5325_hypotheticalprotein
191002___________ +1.12 +1.120.0510.0500.1271249614000139486.5796_
19403____________ +1.06 +1.070.1200.1150.1871485115669159156.6262_
19514____________ +1.19 +1.110.0510.0230.5742786733298308526.6726_snRNA-associatedprotein,Smclass
196911___________ -1.02 -1.010.1670.0760.7131365413334135586.7175_hypotheticalgene
*196534___________ +1.16 +1.340.0060.0250.0101620618722216796.7626_hypotheticalprotein
197170___________ +1.01 -1.000.8560.8940.6321491315008148796.8071_
*19562____________ +1.40 +1.370.0260.0280.0844404261865603786.8506_
197597___________ -1.01 -1.010.8250.6320.7621220812105120876.8945_PhosphoMUtasehomolog
*19519____________ +1.97 +1.830.0000.0000.0002704853169493926.399__
*192242___________ +3.88 +3.070.0000.0000.000544732114011670026.1036_
191805___________ +1.20 +1.110.0400.0190.5151317115831146226.1578_
*191042___________ -3.99 -5.290.0000.0000.0005547501389011048266.2124_porin|voltage-dependentanionchannel(VDAC)
*193644___________ +1.73 +2.020.0010.0050.0031498925883303036.2642_
*196031___________ +1.70 +1.740.0020.0040.0071497025389260736.3159_vacuolarproteinsorting-associatedprotein
*19761____________ -1.10 -1.180.0170.1750.0132982427047253546.3640_
*19742____________ -17.11 -20.470.0000.0000.00039366223012192296.4131_mitochondrialaldehydedehydrogenase
*194301___________ +1.96 +2.030.0010.0030.0021459628609296466.4606_conservedhypotheticalprotein
*196009___________ +1.75 +1.660.0000.0010.0014130672233686866.5089_histonemethyltransferaseinvolvedingeneregulation
*192669___________ +1.41 +1.470.0020.0060.0051688223839247816.5565_revproductadjacenttogag/polproducts
*196272___________ +1.76 +1.690.0000.0010.0011984734872334636.6031_ubiquitinC-terminalhydrolase
*19428____________ -1.20 -1.310.0020.0200.0027310561041557046.6497_kinasesuppressorofIra1
*193091___________ +1.91 +2.050.0010.0040.0041577730144323876.6953_
67405____________ +1.33 +1.320.0020.0070.0051474419593194696.7405_
*196414___________ +1.27 +1.320.0010.0050.0032609033262343536.7840_hypotheticalprotein
195302___________ +1.09 +1.090.0590.0840.0901367314929149486.8289_
*197473___________ +1.76 +1.780.0020.0050.0101521226703270306.8725_conservedhypotheticalprotein
192686___________ +1.09 +1.140.0840.1460.0895227256884598116.116__
*191100___________ +1.54 +1.520.0010.0020.0021682825960256016.739__hypotheticalprotein
*192758___________ +1.62 +1.450.0010.0010.0031988232164289206.1332_
193196___________ +1.14 +1.110.0150.0170.0601354115420150166.1879_hypotheticalprotein
192236___________ +1.26 +1.210.0060.0100.0211276216027154476.2397_
193380___________ +1.14 +1.090.0340.0340.1001239414089135306.2932_
*195198___________ +1.70 +2.020.0030.0100.0091492125412301306.3415_
*195215___________ -1.99 -2.220.0010.0030.0014444622339200166.3906_acyl-CoAthioesterase
191794___________ +1.12 +1.120.0440.0460.1101223213692136806.4373_hypotheticalprotein
191314___________ +1.06 +1.050.0490.0400.1591372614523144636.4877_
*191582___________ +1.62 +1.530.0020.0040.0151310521228200146.5337_memberofmajorfacilitatorsuperfamilymultidrug-resistanceproteinsubfamily1
19986____________ +1.09 +1.110.0270.0370.0641402415307155506.5811_
*19390____________ +1.38 +1.300.0010.0020.0046834194040886886.6274_RhoGTP-bindingproteinregulatingthecellcycle
*19529____________ +1.27 +1.280.0010.0030.0023160240008405726.6741_hypotheticalserine-richprotein
*193293___________ -1.64 -1.340.0010.0010.0076686440718499276.7188_3-oxo-5a-steroid4-dehydrogenase
67639____________ +1.20 +1.210.0080.0120.0321227214744148566.7639_
*197185___________ +1.56 +1.500.0010.0040.0041901929760284666.8085_subunitofhistoneacetyltransferase
*197359___________ +1.16 +1.170.0070.0160.0162118124573248256.8519_zincfingertranscriptionfactor
*197610___________ +1.72 +2.100.0000.0020.0002479642588521836.8958_proteintyrosinephosphatase
193100___________ -1.15 -1.120.5640.3140.9071154610066102916.415__
191439___________ +1.32 +1.270.0040.0080.0151285916938162686.1053_inositolpolyphosphatekinase
193561___________ +1.16 +1.130.0250.0300.0701253014508141106.1600_
19561____________ +1.02 -1.010.4120.2110.8422707427545268366.2140_tRNAdihydrouridinesynthase
*194960___________ +3.57 +3.490.0000.0000.0002368884456825856.2656_sperminesynthase
19272____________ +1.28 +1.320.0030.0090.0091449418605190786.3177_long-chainfattyacidCoAligase
194741___________ +1.15 +1.160.0340.0390.0841245114292143996.3653_hypotheticalprotein
*191693___________ +2.59 +2.630.0000.0010.0011741845065457346.4146_transcriptionalactivator
191186___________ +1.11 +1.060.0410.0230.3152011622340213316.4623_hypotheticalprotein
196124___________ +1.39 +1.360.0040.0070.0141383219249188776.5104_
*192330___________ +1.42 +1.520.0020.0060.0071469220917222886.5579_
*194947___________ -2.17 -2.430.0010.0050.0034177019219171746.6043_conservedhypotheticalprotein
19443____________ +1.17 +1.160.0120.0180.0331688419775195556.6512_subunitofRNApolymeraseIII
*195169___________ +8.02 +7.390.0000.0000.000194091556441433376.6967_amidase
*194004___________ -1.87 -1.670.0000.0000.0018762446860526116.7417_chaperonin
196396___________ +1.09 +1.010.1160.0500.7611244013511126076.7859_
195314___________ +1.07 +1.060.1540.0900.4021298613919137106.8303_
197486___________ -1.13 -1.240.0130.0500.0171996117704161546.8738_ribosomalproteinL6precursor,mitochondrial
196398___________ +1.16 +1.090.0340.0210.2251294615030141416.163__
193793___________ +1.21 +1.200.0080.0110.0351269115383151966.758__
*191738___________ +1.76 +1.670.0000.0010.0022272339959379956.1350_
194972___________ +1.16 +1.130.0210.0220.0781247514512140546.1893_
193945___________ +1.16 +1.090.0400.0310.1681228014299133256.2412_conservedhypotheticalprotein
191200___________ +1.11 +1.120.0280.0260.1071235613685138396.2945_hypotheticalprotein
191822___________ +1.08 +1.110.0230.0340.0551212213072134776.3429_
192514___________ +1.13 +1.110.0200.0270.0551393115685154386.3919_highlyconservedhypotheticalprotein
192878___________ +1.12 +1.030.0630.0280.6681763719770182066.4387_hypotheticalprotein
194783___________ +1.03 +1.040.0840.0410.4911339813854139876.4893_conservedhypotheticalprotein
191397___________ +1.07 +1.040.1560.1030.3341454215604150796.5351_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
196375___________ -1.33 -1.500.0010.0080.0032689720293179386.5827_ribosomalproteinS20
195083___________ +1.04 +1.030.2420.1250.6042094321795214676.6292_
*19541____________ +1.25 +1.470.0030.0110.0051661620846244596.6753_similartobacterialenzymesoftheiron/ascorbateoxidoreductasefamily
193306___________ +1.09 +1.080.0500.0600.0971268013759137026.7201_DNAbindingprotein
196508___________ -1.00 -1.030.5780.5580.4372179921746212386.7652_conservedhypotheticalprotein
*197198___________ +1.31 +1.130.0020.0020.0313165441608357016.8098_CCR4-NOTcomplexprotein|regulationoftranscription
197371___________ +1.07 +1.090.0940.0820.1871330614299145146.8531_transcriptionfactor
197622___________ +1.04 -1.010.3290.1560.9201442114939143486.8970_transcriptionfactorSpt3
192267___________ +1.29 +1.200.0020.0030.0101628520936194856.435__
196080___________ +1.28 +1.200.0060.0080.0271583120303189486.1066_putativeGTPase
194905___________ +1.17 +1.080.0130.0110.1141436216841154846.1618_conservedhypotheticalmembraneprotein
*191267___________ +1.82 +1.910.0000.0020.0011695030903323176.2159_similartoE.coliDnaJ
193168___________ +1.16 +1.090.0470.0300.2401203013950131666.2670_
194727___________ -1.24 -1.310.0030.0140.0052640721272202266.3189_EarlyMeioticInduction
*192398___________ +2.93 +2.340.0000.0000.0003023688488707996.3675_hypotheticalprotein
*191373___________ +1.63 +1.630.0000.0010.0003112450856507696.4159_phosphatidylinositolphosphate5-phosphatase
195714___________ +1.30 +1.240.0050.0090.0211319017128163966.4645_
196233___________ +1.03 +1.060.7340.8000.5052788528736295436.5123_
*191944___________ +2.02 +2.010.0000.0010.0012617252997526156.5595_G-proteincoupledreceptor
194934___________ +1.12 +1.080.0260.0310.0761261714110135776.6055_
196630___________ +1.15 +1.180.0080.0160.0211373015742161546.6527_membraneproteinconfirmedbycDNAcloning
195157___________ -1.29 -1.250.0020.0030.0092658820662212036.6979_conservedhypotheticalmembraneprotein
194017___________ -1.01 -1.010.8010.9390.5521677316539165636.7430_hypotheticalprotein
194577___________ +1.06 +1.050.0990.0680.2611236413165129496.7876_maybeinvolvedincAMP-PKAsingaling
*195328___________ +1.19 +1.120.0040.0050.0243631543116408386.8316_
*197499___________ +2.24 +2.220.0000.0000.000529831186161175556.8751_conservedhypotheticalprotein
194761___________ +1.19 +1.170.0130.0190.0401262615040147846.177__
192012___________ +1.29 +1.230.0050.0110.0151467118902180376.778__generalnegativeregulatoroftranscription
192293___________ +1.47 +1.290.0030.0040.0151273318753163706.1366_
193491___________ +1.42 +1.310.0020.0060.0071461720775191446.1909_DNA-bindingfactorsubunit1
*194952___________ +2.39 +2.520.0000.0010.0012458258803618456.2431_
19188____________ +1.18 +1.130.0120.0120.0651266814955143346.2962_
*191166___________ +1.27 +1.420.0030.0130.00670912898271006046.3444_
196027___________ +1.26 +1.170.0510.0330.2361328616689155216.3931_hypotheticalprotein
*64403____________ +1.49 +1.360.0010.0030.0061948328979264286.4403_
*195725___________ +1.60 +1.630.0000.0020.0011835029357298446.4905_
*192131___________ +1.13 +1.240.0110.0270.0202572829077318416.5364_
193874___________ +1.33 +1.170.0100.0090.0781327817613155176.5846_
*194399___________ +1.19 +1.220.0250.0560.0383076836669375466.6308_conservedhypotheticalprotein
196660___________ -1.07 +1.280.1100.2680.0831969721846082522116.6769_unknownprotein
*193319___________ +1.22 +1.310.0010.0050.00280739987721061026.7214_thioredoxin
195276___________ +1.11 +1.120.0650.1480.0651477816466165036.7666_conservedhypotheticalprotein
*197210___________ +1.90 +2.010.0010.0030.0031699432298342116.8110_conservedhypotheticalprotein
197383___________ +1.18 +1.170.0120.0150.0451362416116160076.8543_requiredforcomplexglycosylation
*197638___________ +1.57 +1.640.0010.0050.0041949430670320616.8987_
195528___________ -1.18 -1.110.0090.0150.026116539868104906.454__
*191751___________ +1.57 +1.510.0010.0020.0031630125580246566.1080_
*193076___________ -1.57 -1.830.0010.0030.0036442440997352556.1633_conservedhypotheticalprotein
*191142___________ +2.04 +1.920.0000.0010.0002010841047385766.2175_
19242____________ +1.15 +1.150.0220.0240.0731253614419143686.2688_GPI-anchoredorsecretedaspartylprotease
*194077___________ +1.64 +1.520.0020.0040.0091402623000213016.3203_involvedinmaintenanceofphospholipidlevelsandmannosylationofsphingolipids
19689____________ +1.24 +1.220.0040.0080.0171348916770164506.3690_lysophospholipaseB
*195480___________ +1.35 +1.310.0010.0030.0022002826992261686.4175_
195496___________ -1.02 +1.010.6140.3570.8892358623073237376.4661_transmembraneaminoacidtransporter
*193910___________ +1.59 +1.310.0000.0010.0041870529729245796.5139_
*191843___________ +1.23 +1.240.0080.0270.0142457130151304726.5611_glucosyltransferaserequiredforN-linkedglycosylationpathway
194177___________ +1.08 +1.070.0460.0410.1381436715535153486.6071_histidinol-phosphateaminotransferase
*196643___________ +1.33 +1.500.0010.0030.0021869724826280746.6540_malonyl-CoA:ACPtransferase
*196844___________ -21.40 -19.240.0000.0000.00034927716318181506.6993_isocitratelyase
*194031___________ -1.30 -1.240.0090.0160.0254529834737363956.7444_conservedhypotheticalprotein
*194591___________ -6.51 -6.220.0000.0010.0019918815235159416.7890_carnitineacetyltransferase
*195342___________ +1.55 +1.740.0010.0030.0021843128604320826.8331_conservedhypotheticalprotein
197512___________ -1.14 +1.020.7550.4860.9344316838020440666.8764_n-alkaneinduciblecytochromeP-450
19195____________ +1.23 +1.270.0070.0110.0261336416468169576.196__
*191907___________ -1.33 -1.530.0000.0030.0014655234888304456.797__
191303___________ +1.13 +1.040.0890.0490.3841620618268168056.1384_
193356___________ +1.25 +1.160.0040.0050.0261255215737145276.1925_separinprotein
192287___________ +1.03 +1.030.4820.2850.6761529815779156836.2447_DNA-directedRNApolymeraseI
*19607____________ +1.35 +1.330.0080.0130.0241653422365219426.2980_
192920___________ +1.01 -1.090.2410.8320.1201855218809170376.3458_highlyconservedhypotheticalprotein
*19910____________ +1.13 +1.100.0300.0380.0712330526246256676.3948_snRNPfromU4/U6andU5snRNPs|splicingfactor
*195580___________ +1.86 +1.580.0010.0020.0032585248146409706.4425_
191070___________ +1.06 +1.050.1060.1000.1801846219643193926.4919_conservedhypotheticalprotein
192149___________ +1.08 +1.060.0650.0480.2042506026987264676.5381_
193889___________ +1.01 -1.000.7050.4950.7121469414863146226.5860_componentoftheCOPII-coatedvesicles
*194384___________ +1.77 +2.000.0040.0080.0151242021928248206.6322_
*196674___________ +1.26 +1.250.0040.0110.0112025425429253846.6783_geranylgeranyldiphosphatesynthase
19344____________ +1.01 +1.010.5900.5320.4691334513478134846.7227_
*195263___________ +1.18 +1.100.0250.0190.1403315238995365766.7679_3-phosphoglyceratedehydrogenase,serinebiosynthesis
197223___________ +1.13 +1.130.0210.0380.0421359515393152966.8123_conservedhypotheticalprotein
197395___________ +1.00 -1.000.7860.9730.5321354113554135266.8555_hypotheticalprotein
*197655___________ -1.18 -1.370.0100.1680.0082033741716791481366.9003_DNA-directedRNApolymeraseII,215KDsubunit
192028___________ +1.13 +1.060.1350.0730.4382236925307236436.473__
193734___________ +1.42 +1.300.0020.0050.0091383719614179316.1098_
191599___________ +1.24 +1.170.0120.0140.0481324116454155336.1648_hypotheticalprotein
62192____________ +1.16 +1.160.0070.0110.0261233514299143706.2192_
192713___________ +1.13 +1.190.0150.0320.0291227513849146476.2706_
191032___________ +1.18 +1.170.0060.0110.0221515617901176576.3219_CREBliketrancsriptionalrepressor|bZIPprotein
*1994_____________ -1.23 -1.400.0170.0570.0239739078937695556.3706_hypotheticalprotein
*194496___________ +1.45 +1.430.0000.0010.0014060559079580996.4188_
*192579___________ +1.45 +1.460.0020.0050.0081928028049280596.4677_
*19220____________ +1.38 +1.860.0000.0010.0001090761508762032666.5154_
19331____________ +1.06 +1.030.2320.1270.5302282324176235696.5628_
192180___________ +1.12 +1.060.0460.0270.2771381615479146086.6082_
19664____________ +1.21 +1.130.0200.0220.0741252315112141176.6557_hypotheticalprotein
*196856___________ +2.26 +2.350.0010.0030.0031465433072344786.7005_nucleoporin
*192097___________ +1.72 +1.820.0010.0030.0021349623229246266.7459_
194605___________ +1.02 -1.020.5260.4070.4991453814890142146.7903_
195360___________ -1.13 -1.120.0530.1410.0524308838154386276.8349_RNApolymeraseIIIC11subunit
*197527___________ +1.45 +1.670.0020.0060.0041552222572258846.8778_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
195223___________ +1.26 +1.190.0110.0140.0431466618462174576.211__
191180___________ +1.06 +1.000.5970.3810.7061848219537185476.820__conservedhypotheticalprotein
*192517___________ +32.24 +21.620.0000.0000.000159505142393448316.1398_putativeiontransportersimilartothemajorfacilitatorsuperfamily
*193496___________ +2.81 +2.570.0000.0000.0002094858944538466.1939_
*193605___________ +1.60 +1.380.0020.0030.0091783928602246706.2461_peroxisomalperipheralmembraneprotein
19793____________ +1.24 +1.200.0070.0110.0271474818356177236.2993_cyclin-dependentkinase-activatingkinase
*191121___________ +2.75 +2.940.0000.0000.0002240161676658946.3473_conservedhypotheticalprotein
191515___________ +1.22 +1.280.0040.0180.0081443617568184886.3966_
195597___________ +1.32 +1.250.0060.0090.0251432618939179706.4439_
*191057___________ -1.76 -1.690.0010.0020.0025744632587339956.4932_conservedhypotheticalprotein
*196176___________ +1.33 +1.380.0020.0040.0055103067997704616.5397_ERprotein-translocationcomplexsubunit
193138___________ -1.18 +1.020.0760.0320.847106650907341089236.5875_U3snoRNPproteinsimilartomammalianfibrillarin
*195112___________ -3.86 -3.850.0000.0000.0007309471895271898496.6338_transketolase1
*196690___________ +1.30 +1.440.0000.0020.0012406631367345626.6799_hypotheticalprotein
19356____________ +1.02 -1.000.8120.5970.7921278213011127536.7240_glutathioneS-transferase
*195251___________ +1.16 +1.200.0100.0270.0181935522475232626.7691_potentialfungalZn(2)-Cys(6)binuclearclusterdomain
*197237___________ +1.33 +1.440.0010.0030.0022017226741289926.8137_conservedhypotheticalprotein
*197409___________ -2.21 -2.010.0000.0000.00110427047276518626.8569_componentofCOPIIcoatofER-derivedvesicles|p24proteinfamily
*197668___________ -1.51 -1.370.0020.0040.0142548216839186566.9016_alpha-glucosidase(maltase)
193338___________ +1.32 +1.190.0030.0050.0151261216643149656.494__
19581____________ +1.24 +1.190.0060.0100.0211238215311146746.1112_
*193161___________ +1.41 +1.440.0000.0020.0012260331770325016.1667_putativeTATA-bindingprotein-bindingprotein
*195541___________ +1.59 +1.600.0030.0060.0091782028289284566.2205_
*194432___________ +1.76 +1.530.0030.0060.0101615828435247796.2722_
*191732___________ +1.65 +1.740.0030.0070.0101323421901230056.3232_
192795___________ +1.25 +1.210.0080.0130.0261388117350167406.3724_RNAbindingproteinsimilartohumanLaantigen
*192347___________ +1.06 +1.110.0190.3430.0122584427289288166.4204_
*192734___________ +3.39 +3.440.0000.0000.0002449082933843636.4690_conservedhypotheticalprotein
19207____________ +1.30 +1.300.0020.0050.0081456218994190006.5165_extremelyserinerichprotein
19316____________ -1.05 -1.030.8060.5560.8835220049682508826.5642_proteintransportfactor
193426___________ +1.02 +1.000.7090.5090.6961526815559152966.6099_translationinitiationfactoreIF5A.1
19676____________ -1.05 -1.050.1330.1100.2303176230307302756.6569_microtubule-bindingprotein
191903___________ +1.06 +1.080.7060.6620.5316825672433734746.7017_phosphatidylinositol3-kinase
*192084___________ +1.78 +2.030.0000.0020.0011947734681395296.7472_
*194618___________ -1.51 -1.330.0030.0050.0182364401563161780966.7917_fructose-bisphosphatealdolase
*197281___________ +1.29 +1.230.0130.0280.0262232228797273616.8362_pyruvatedehydrogenasekinase
*19631____________ -1.21 -1.230.0280.0560.0451494181231131219166.8795_
625______________ +1.07 +1.050.2600.1680.4251227413077128626.25___
*191187___________ +1.93 +1.980.0040.0120.0091721033147340116.517__
19795____________ +1.13 +1.300.0040.0210.0071364415418176916.1135_
194699___________ +1.03 +1.040.3450.2360.4501278813198133456.1686_
*193606___________ +1.39 +1.400.0020.0060.0071664223139233376.2221_
194192___________ +1.15 +1.200.0090.0360.0131318015160158526.2743_proteinphosphataserequiredformitosis
195563___________ +1.07 +1.040.1390.0940.3111385814768144066.3249_
193080___________ +1.06 +1.030.2070.1620.3011209212764124596.3740_
194416___________ +1.00 -1.010.8340.6240.8021526815325151646.4222_
194653___________ -1.00 -1.000.5040.9340.2821241812393124066.4704_hypotheticalprotein
192410___________ +1.04 +1.050.1660.3490.1151228812732129316.5184_
193980___________ +1.04 +1.050.3600.2780.3991245312962131326.5655_
192907___________ -1.00 -1.020.5540.8000.3341289812841127036.6115_hypotheticalprotein
*192765___________ +1.36 +1.690.0010.0060.0011510220583255456.6587_hypotheticalprotein
*191889___________ +1.38 +1.270.0020.0050.0072393033122304876.7031_similartophosphoglyceratemutase
192070___________ +1.02 +1.020.5700.3610.6861192312206121176.7485_remodelsthestructureofchromatincomplex
197005___________ +1.16 +1.250.0050.0110.0141253314544156056.7931_MajorRepeatSequence
197295___________ +1.10 +1.170.0190.1030.0191699518674199246.8376_multicopysuppressorofclathrindeficiency
196820___________ +1.12 +1.050.0230.0140.2271250714039131056.8812_
Cacht2___________ -1.28 -1.170.0050.0120.0141154690499891Cacht2_
*196952___________ +1.99 +2.150.0000.0020.0002259544976486886.231__
*193555___________ +2.40 +1.800.0010.0020.0033621787003652236.837__
195754___________ -1.04 -1.010.6390.3730.9794832246540479056.1415_
191920___________ +1.06 +1.100.1060.3210.0711327614060145836.1959_putativecellwallproteinofthePIRfamily
1961_____________ -1.10 -1.100.1720.0980.4412488022606226536.2479_mitochondrialinnermembraneproteasesubunit
191251___________ +1.26 +1.430.0030.0110.0061260715947180146.3008_functionalhomologueofhumanBRRN1involvedinchromosomesegregation
194269___________ +1.16 +1.240.1470.5900.0782760831940342526.3488_hypotheticalprotein
*194773___________ +6.12 +9.980.0000.0000.00014433882791440956.3984_alternativeoxidase
195514___________ -1.14 -1.110.0490.1070.0561375012097124026.4456_conservedhypotheticalprotein
195848___________ -1.11 -1.140.0060.0250.0101193310747104606.4950_hypotheticalprotein
*196192___________ -1.41 -1.690.0030.0100.0085102836285302146.5413_hypotheticalprotein
*192256___________ +1.23 +1.340.0080.0590.0092346028843314136.5890_hypotheticalankyrin-repeatprotein
192006___________ +1.20 +1.190.1900.0960.5771500218034177846.6354_EnhancedAdherencetoPolystyrene|glycosylphosphatidylinositol-anchoredcellwallproteininvolvedinadhesiontohumanepithelialcells
*196705___________ +2.05 +1.710.0010.0020.0022807857499481346.6814_conservedhypotheticalprotein
*194444___________ +2.06 +2.420.0000.0010.0002169744712524256.7257_4-nitrophenylphosphatase
195237___________ -1.00 -1.020.4420.2310.8501384413819136086.7705_vacuolarH+-ATPaseassemblyprotein
197252___________ +1.03 +1.010.4360.3970.3771216812499123466.8152_hypotheticalprotein
197425___________ -1.39 -1.350.0020.0050.0072898620868215136.8585_uracilDNAglycosylase
196005___________ +1.06 +1.020.6460.4170.7401284213599130416.9031_
*194953___________ +2.21 +1.970.0000.0000.0002513555483495506.44___
196203___________ +1.45 +1.420.0020.0060.0071426120623202586.535__
191789___________ +1.27 +1.180.0040.0060.0231261815992148826.1157_conservedhypotheticalprotein
1911_____________ +1.06 +1.080.0690.1030.0921352414384145616.1704_
*193351___________ +3.36 +3.830.0000.0000.0002096470419802196.2237_hypotheticalprotein
*192356___________ +3.14 +3.660.0000.0010.0002221369681813926.2758_
*192865___________ +1.46 +1.390.0010.0030.0062228632570309996.3265_
*194909___________ +1.94 +1.770.0000.0010.0022160041811381326.3756_cellwallbiosynthesiskinase
194900___________ +1.15 +1.160.0060.0100.0191423016318165136.4237_
19570____________ +1.20 +1.140.0090.0100.0581327015932150756.4719_
194288___________ +1.30 +1.300.0080.0110.0361408218298182716.5197_
196143___________ -1.10 -1.110.0520.0510.1251972317991177846.5670_
66128____________ -1.11 -1.090.0410.0800.0572204819844202616.6128_
194245___________ +1.04 +1.040.5950.3780.7081282013321132976.6600_
191874___________ +1.01 -1.000.8360.6260.8051228612453122466.7045_
192057___________ +1.02 +1.030.5650.3500.7061243112683127996.7497_
197019___________ -1.13 -1.090.0330.0570.0571956417332178916.7945_mitochondrialribosomalprotein
*197308___________ +3.13 +2.580.0000.0000.0002287671562590626.8389_alpha-1tubulin
196807___________ +1.07 +1.040.4450.3700.4151834119591190156.8825_
Cakre6___________ -1.27 -1.260.0030.0210.0041169092109262Cakre6_
*19385____________ +3.98 +3.730.0000.0000.00025496101456950956.246__
*193187___________ +1.76 +1.530.0040.0080.0161305823044199686.852__
*192631___________ +1.44 +1.760.0000.0010.0003792854717666736.1436_
*191948___________ +1.27 +1.190.0020.0040.0082161627395256576.1974_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194072___________ +1.30 +1.210.0090.0160.0261369917855165866.2493_
193225___________ +1.28 +1.220.0090.0100.0451241415914151436.3024_putativesensor/transporter
*195191___________ +1.95 +1.710.0060.0080.0261319825784225716.3502_hypotheticalprotein
*192937___________ +1.43 +1.360.0020.0040.0071610823069218456.4001_phosphomannomutase
195527___________ -1.04 +1.040.6610.4410.7183387032447352526.4469_DNase/RNase
192471___________ +1.03 +1.020.8750.6410.9212259423162230796.4965_
196196___________ +1.02 -1.070.1820.7900.0902281623381213506.5428_hypotheticalprotein
*194927___________ +1.26 +1.190.0020.0030.0213878048762462356.5905_
191990___________ +1.26 +1.310.0090.0140.0281384717381180936.6370_
194106___________ +1.14 +1.180.0060.0170.0131798220517212696.6830_conservedhypotheticalmembraneprotein
19908____________ +1.27 +1.290.0050.0120.0121328616900170766.7270_
*196973___________ +2.19 +2.090.0000.0010.0011901741642396636.7719_mitochondrialATP-dependentprotease|possiblenuclearproteinwithaleucinepattern
197267___________ +1.04 +1.000.2440.1100.9461208412569121156.8167_conservedhypotheticalprotein
*197438___________ +2.25 +2.390.0010.0030.0021569035252375116.8599_
*195991___________ +1.57 +1.520.0020.0060.0091702526767258816.9046_ATPdependentRNAhelicase
*19376____________ -1.94 -2.260.0000.0020.0013295717005145606.65___1,4-butanedioldiacrylateesterase
192400___________ +1.08 +1.070.0780.1180.0971248513516134116.559__
*191814___________ +1.60 +1.410.0010.0020.0033143050374443196.1175_
195575___________ +1.00 +1.020.9460.7640.9681300513043132586.1722_conservedhypotheticalprotein
191486___________ +1.03 +1.060.4160.7650.2321264412993134406.2256_hypotheticalprotein
191305___________ +1.01 +1.010.9380.9920.7521244412568126276.2775_?tRNA(guanine)methyltransferase
193611___________ -1.17 -1.270.0050.0240.0092403420568189376.3281_NADH-ubiquinoneoxidoreductase
193468___________ +1.11 +1.100.0270.0590.0401223613521134766.3771_
191836___________ +1.02 +1.030.9910.9660.9111595016206163846.4250_APendonuclease
*193345___________ +1.52 +1.830.0030.0190.0041999830395366926.4737_
194805___________ -1.03 +1.010.8450.6040.8931190611582119686.5212_
19597____________ -1.02 -1.090.3490.2980.3522929528663268626.5683_arylformamidase
195837___________ -1.01 +1.020.5700.6770.3761299412897132526.6141_relatedtovariousbacterialaminotransferases
194230___________ +1.00 -1.030.4650.4510.3711388613918134826.6615_B-typesubunitofproteasome
67062____________ -1.02 -1.030.7110.5970.5861169211478114066.7062_
193818___________ -1.01 -1.010.8090.5760.8291194611803118576.7513_hypotheticalprotein
197032___________ +1.08 +1.050.1190.1130.1871237813428130476.7958_hypotheticalprotein
197321___________ -1.02 -1.020.4910.3210.5851192611668116756.8402_conservedhypotheticalprotein
*196793___________ +1.96 +1.830.0020.0040.0081510629584275726.8838_hypotheticalprotein
41477____________ -1.04 -1.050.3660.5560.2301177211278112294.1477_
*191035___________ +1.79 +1.730.0010.0040.0031520427252263686.265__
191229___________ +1.21 +1.170.0150.0400.0251408816980165136.869__
*61452____________ +1.41 +1.340.0070.0210.0122049328983274886.1452_
19252____________ +1.25 +1.300.0030.0200.0041631220317211926.1989_conservedhypotheticalprotein
19105____________ +1.09 +1.050.0660.0840.1051281513972134506.2509_
191699___________ +1.08 +1.130.1170.1010.2071371114869154506.3040_
*194706___________ +2.23 +2.440.0000.0030.0012164048169528766.3515_lowsimilaritytoprionprotein
19693____________ +1.08 +1.080.1100.1610.1191256613634136286.4014_
193188___________ +1.22 +1.320.0040.0220.0051395816984184226.4486_
193481___________ +1.02 +1.070.4990.6330.3232050220960218876.4978_DEAD-bixATP-dependentRNAhelicase
196291___________ +1.11 +1.100.0330.0640.0491275514209140756.5442_
1927_____________ +1.08 +1.070.3650.5360.2341972221239211126.5921_hypotheticalprotein
191419___________ +1.21 +1.220.0140.0120.1061427617249173506.6388_exocystcomplexcomponent
194092___________ +1.01 -1.020.9680.8160.9981299813156127586.6844_hypotheticalprotein
*19894____________ +1.15 +1.140.0450.1900.0361916522086219276.7283_Golgiguanyl-nucleotideexchangefactor
*196985___________ +1.47 +1.780.0010.0040.0041289518916229156.7731_transcriptionfactorwithfungalZn(2)-Cys(6)binuclearclusterdomain|TY1enhanceractivator
19933____________ -1.02 -1.040.4880.5870.3271664216241160686.8182_ubiquitin-conjugatingenzyme
*197451___________ +1.58 +1.900.0010.0030.0011911230185363566.8611_serine/threoninekinase
195977___________ +1.04 +1.080.1070.2190.0911283113329138956.9060_3-oxoacyl-[acyl-carrier-protein]-synthase
194751___________ +1.30 +1.220.0020.0050.0081658021493202776.89___
*19983____________ +1.52 +1.380.0020.0040.0081457322126200616.579__
191818___________ +1.16 +1.130.0090.0120.0341258114651142096.1194_
*19448____________ +1.84 +1.790.0010.0020.0031641830178293866.1737_
*196255___________ +1.52 +1.520.0010.0030.0021684425569256006.2270_conservedhypotheticalprotein
*194337___________ +2.51 +2.460.0000.0000.0011531338469376136.2795_
*194916___________ +1.12 +1.150.0020.0050.0092620829223301116.3295_conservedhypotheticalprotein
192933___________ +1.15 +1.120.0160.0160.0751258214482140386.3788_
*192218___________ +2.05 +2.010.0000.0000.000610691252981229966.4263_hypotheticalprotein
192108___________ +1.25 +1.160.0050.0070.0261372017208159506.4752_
194151___________ +1.08 +1.050.1090.0820.2401288613973135656.5227_
192988___________ +1.21 +1.130.0280.0550.0451496118082168886.5701_conservedhypotheticalprotein,possibleN-epimerase
195824___________ -1.06 -1.070.1750.3470.1231839517383172246.6154_alpha/betahydrolasefolddomainprotein
195797___________ +1.03 -1.030.2820.1490.6161227512692119466.6631_phosphatidylinositolphospholipaseC
19493____________ +1.12 +1.040.9620.8240.9111037201166361081636.7078_ribosomalproteinL15B
193833___________ +1.12 +1.050.0520.0310.2721200013430125826.7529_
*197046___________ +1.70 +1.790.0000.0010.0014154570706743146.7972_transcriptionfactor
197332___________ +1.04 +1.090.1380.0990.2811236712873135376.8415_
196781___________ +1.15 +1.040.0390.0180.5861307215041135816.8850_possiblezinc-fingerprotein
42184____________ +1.05 +1.040.1960.1170.4271217612752126614.2184_
194513___________ +1.35 +1.250.0080.0080.0491381618649172056.280__
19779____________ +1.43 +1.330.0020.0040.0071590922726211666.894__
192662___________ +1.21 +1.160.0090.0120.0361334716105154916.1467_hypotheticalprotein
*191680___________ +1.65 +1.590.0000.0000.0012536141893402366.2002_vacuolarATPaseV1domaincatalyticsubunitA
62528____________ +1.18 +1.090.0270.0260.1031356415999147686.2528_
194887___________ +1.17 +1.140.0120.0180.0361231014401139976.3053_
*19649____________ +1.74 +1.540.0060.0080.0261348523482208006.3534_
*195095___________ +1.84 +1.840.0020.0070.0061514427903278686.4030_
192837___________ +1.23 +1.170.0120.0120.0631525818842177826.4498_UDP-glucose:dolichyl-phosphateglucosyltransferase
194520___________ +1.10 +1.050.0930.0610.2801399415335147246.4991_glucokinase
194679___________ -1.04 +1.150.1620.2190.1552149220572247726.5457_amino-acidpermease
19203____________ -1.05 -1.140.0860.8200.0412159620523188916.5935_Sin3pbindingprotein
*191544___________ +1.19 +1.300.0030.0200.0053352039875436756.6402_hypotheticalprotein|coiledcoils
194080___________ +1.18 +1.110.0250.0330.0611451817170161416.6856_hypotheticalprotein
19878____________ +1.04 +1.100.0990.2730.0723047331567335326.7299_NuA4histoneacetyltransferasecomplexcomponent
196997___________ +1.07 +1.010.2260.1010.9391181212626119086.7743_FUN34-relatedprotein|glyoxylatepathwayregulator
*19945____________ +1.49 +1.410.0010.0030.0091842227366260396.8194_classEvacuolar-proteinsortingandendocytosisfactor
*195388___________ +1.17 +1.210.0110.0310.0192050124004247856.8624_chromatinbindingprotein
*195965___________ +1.36 +1.270.0020.0040.0081810324689230026.9072_ubiquitinfusiondegradationprotein
*192479___________ +1.81 +2.000.0000.0030.0011332924070266796.107__
195373___________ +1.07 +1.060.1550.1110.2991199912874126766.599__
61211____________ +1.07 +1.110.0270.1680.0221232513178136626.1211_
196078___________ +1.04 -1.020.9460.8200.8501973620499192876.1756_
193770___________ +1.06 +1.060.3550.3540.3061417014955149676.2288_acetylornithineaminotransferase
19407____________ +1.01 -1.020.6440.7070.4391353113728132636.2817_translationinitiationfactoreIF-2Bepsilonsubunit,GEF
*193651___________ -1.34 -1.770.0220.0300.0577708057337434936.3311_

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
192555___________ -1.12 -1.220.0190.0540.0272437421750200356.3804_orotatephosphoribosyltransferase
*192608___________ -1.70 -2.340.0030.0120.00712202271952522106.4277_alcoholdehydrogenaseII
192369___________ -1.01 -1.010.9360.7910.8501236412245122406.4767_or(ISS)nrecognitioncomplexsubunit
193856___________ +1.18 +1.200.0080.0320.0111358716041162986.5246_celldivisioncontrolprotein
192974___________ +1.12 +1.190.0250.0710.0321272714197151696.5715_ER-Golgitransport
192487___________ -1.01 +1.020.8240.7050.6811194411812121796.6168_conservedhypotheticalprotein
195812___________ -1.00 +1.030.8380.8630.6161174711703120546.6646_conservedhypotheticalprotein
19480____________ +1.20 +1.200.0040.0110.0091270015255152086.7091_conservedhypotheticalprotein
196558___________ +1.03 +1.030.4370.2750.5761336413726137606.7546_cytoplasmicGTPase-activating
195024___________ +1.21 +1.260.0060.0140.0141467017756184576.7985_6-phosphogluconatedehydrogenase
197124___________ -1.08 -1.280.0660.2070.0545696052850444986.8427_
196769___________ -1.03 -1.060.1320.2650.1041295712532122716.8864_
42519____________ -1.01 +1.000.9310.7980.8261264212497126634.2519_
*192881___________ +1.56 +1.380.0010.0020.0031441822504198496.296__
*194772___________ +2.43 +2.510.0000.0020.0012160952552541656.920__
*194952___________ +3.18 +3.190.0000.0020.001345931099761103876.1485_hypotheticalprotein
194902___________ +1.23 +1.120.0190.0290.0451441017787161366.2023_trans-aconitatemethyltransferase
194766___________ +1.27 +1.200.0020.0060.0051418418043170196.2542_componentoftheARGRregulatorycomplexwhichregulatesarginine-responsivegenes
193794___________ +1.27 +1.220.0030.0090.0091253615926153246.3067_SUppressorofROK1|zincfingertranscriptionfactor
*19862____________ +1.29 +1.230.0050.0170.0091978625455244366.3552_hypotheticalprotein
195814___________ +1.04 +1.100.0820.4400.0461588916582174046.4045_hypotheticalprotein
195644___________ +1.05 +1.040.9710.9260.8482419425369251156.4513_conservedprotein|sporecellwallbiogenesis
*194506___________ +1.42 +1.510.0100.0820.0104260060503643866.5005_homocitratesynthase
193740___________ +1.15 +1.220.1620.7100.0812184625021266036.5469_
195145___________ +1.09 +1.070.0570.0910.0801218413221129766.5952_
191559___________ +1.15 +1.130.4490.3290.4782604529926293136.6415_
*196722___________ +1.16 +1.280.0150.0520.0211951622544249446.6870_
*196926___________ +1.39 +1.290.0060.0100.0253579849607461086.7312_celldivisioncontrolprotein25
*193021___________ +1.21 +1.250.0110.0170.0351876622776233936.7758_hypotheticalprotein
19956____________ +1.08 +1.070.0600.0470.1841253413500133996.8209_
195404___________ +1.05 +1.080.1230.4770.0701408714750151996.8641_
195949___________ +1.10 +1.330.0090.0880.0091302614387172936.9086_
19140____________ +1.17 +1.160.0070.0110.0291269614858147706.126__hypotheticalprotein
*191641___________ +3.87 +4.770.0000.0000.0001767268346842656.623__
*192706___________ +1.35 +1.380.0000.0020.0014162656239575916.1232_
61774____________ +1.13 +1.110.0150.0190.0541269214404140866.1774_
191539___________ +1.12 +1.060.0960.3310.0631199413380127186.2305_
194457___________ +1.22 +1.110.0170.0190.0671479818080164686.2834_
195046___________ +1.15 +1.080.0260.0180.1761239214212134046.3323_proteinfarnesyltransferase,betasubunit
*192643___________ +1.31 +1.200.0080.0100.0402139827976257766.3820_RNApolymerasesI,II,andIIIsubunit
193545___________ +1.26 +1.190.0070.0100.0301287616252152676.4291_proteinkinasepotentiallyinvolvedinseptationduringcytokinesis
*195626___________ +3.06 +3.230.0000.0000.000721802209322333736.4785_conservedhypotheticalprotein
*196553___________ -1.43 -1.250.0010.0020.00511782882177939846.5261_conservedhypotheticalprotein
*191261___________ +1.36 +1.390.0010.0030.0042065028180287366.5728_mRNAcappingenzymealphasubunitandguanylyltransferase
195773___________ +1.18 +1.140.0070.0090.0331460717302166966.6184_
192957___________ +1.03 +1.040.2430.1680.3791256112908130516.6659_conservedhypotheticalprotein
191466___________ -1.33 -1.370.0010.0040.0032508518816183506.7107_RNAexonuclease|oligoribonuclease
196574___________ -1.00 -1.010.9760.8390.9901260112539124776.7562_n-alkaneinduciblecytochromeP-450
*195011___________ +1.30 +1.340.0010.0030.0012842437077380446.7998_microtubuleorientation,karyogamyprotein
*197111___________ +1.33 +1.250.0010.0030.0042391631839299386.8442_involvedinmitochondrialdivision
196754___________ -1.07 +1.020.5980.3460.8813646634064373106.8877_hypotheticalprotein
42761____________ -1.04 -1.030.3770.5610.2381154811066111594.2761_
*19646____________ +1.79 +1.770.0030.0070.010812781451501434766.313__
191493___________ +1.48 +1.390.0060.0100.0221298419263180196.936__
193529___________ +1.44 +1.270.0050.0050.0451394220140176776.1501_conservedhypotheticalprotein
*193526___________ +1.19 +1.160.0280.0360.0682514630001292736.2038_
193785___________ +1.25 +1.170.0050.0070.0211618220149189116.2556_DnaJ-likechaperone
191215___________ +1.13 +1.070.0360.0260.1741415616008151466.3082_hypotheticalprotein
192274___________ +1.21 +1.170.0080.0110.0321295115689150976.3568_
*193916___________ +1.62 +1.430.0010.0030.0051560025260222646.4059_
*196220___________ +1.36 +1.390.0050.0090.0211350918433188336.4533_
*194201___________ +1.42 +1.270.0150.0130.1001376119498175436.5019_
192697___________ +1.08 +1.100.1020.1150.1451237313393136406.5484_
*195133___________ +1.19 +1.150.0170.0510.0242175225962250476.5965_hypotheticalDNAbindingprotein
*191643___________ -2.46 -2.520.0010.0020.0044625818778183256.6429_mitochondrialrhomboidprotease
*196736___________ -1.13 +1.040.0400.0200.4203932234740409306.6885_conservedhypotheticalprotein
196940___________ +1.02 +1.000.4790.2660.7701191212131119676.7325_
193034___________ +1.10 +1.130.0490.0510.1161211413316137356.7770_
19974____________ +1.06 +1.040.0620.0420.2271197212655124566.8222_
*195417___________ -1.45 -1.410.0020.0060.00811167777092793246.8653_derepressoroftelomericsilencing
195935___________ +1.20 +1.190.0030.0080.0101627819457192936.9102_coiledcoilprotein
195107___________ +1.26 +1.120.2090.2270.2133035338135341416.142__
191027___________ +1.03 -1.000.7980.5580.8411218612496121506.648__phosphatidylinositoltransferprotein|drugresistance
192449___________ -1.00 +1.070.2560.9410.1251423714203152426.1248_
192915___________ +1.06 +1.070.2230.3420.1671610917047172266.1791_nucleosidephosphatase(apyrase)
191036___________ +1.08 +1.040.8510.8860.6271863420112193176.2321_mannosyl-oligosaccharide1,2-alpha-mannosidase
191195___________ -1.06 -1.060.1560.1140.2891722016232162426.2848_mitochondrialintermediatepeptidaseinvolvedinproteinimport
1933303__________ +1.02 +1.010.6990.6050.5611202812224121126.3337_NA
194875___________ -1.01 +1.020.7300.9640.4731212012029124096.3835_
*194479___________ +1.40 +1.680.0020.0130.0031295018089217296.4307_
19275____________ +1.07 +1.150.0280.1090.0291285313746147236.4804_RNasePandRNaseMRPsubunitinvolvedinRNAprocessing
196540___________ +1.56 +1.400.1120.2650.085736951148851028696.5274_PFK2
191665___________ +1.02 -1.000.9980.9590.9811400214217139676.5740_alpha-1,2-mannosyltransferaseinvolvedinn-linkedando-linkedglycosylation
196590___________ -1.03 -1.040.3720.2980.3901209211771116506.6202_vacuolarATPaseassemblyprotein
192945___________ +1.03 +1.030.5620.5090.4491289713240132926.6672_
191451___________ -1.00 -1.020.8830.8830.6761237912330121396.7121_
196587___________ +1.00 -1.010.8010.6200.7251189511944118236.7575_conservedhypotheticalprotein
194996___________ +1.01 +1.010.9150.7350.8591212912270122436.8013_conservedhypotheticalprotein
197098___________ +1.01 -1.000.6110.3550.8881251812640124806.8455_transcriptionfactor
196740___________ +1.02 +1.070.3100.5650.1851240712630132956.8891_RNAsplicingfactor
43027____________ -1.24 -1.180.0050.0150.01111720943099434.3027_
*196556___________ +3.73 +3.650.0000.0010.0002037575998743336.330__
19236____________ -1.06 -1.340.1310.1470.1645111248153381146.954__
193624___________ +1.22 +1.260.0040.0150.0071265115418159906.1516_
*19364____________ +1.81 +1.710.0090.0350.0133367661117574886.2055_vacuolarATPase
*193364___________ +1.44 +1.530.0100.0620.0124346862492665046.2575_
194563___________ +1.08 +1.100.0740.2130.0601265113672139146.3095_conservedhypotheticalprotein
192752___________ -1.08 -1.040.5410.3030.8503351631053321556.3584_zinc-fingertranscriptionfactor
192366___________ +1.13 +1.140.0140.0410.0231262414294144106.4074_hypotheticalprotein
1960_____________ -1.16 -1.210.0500.0510.1182540821887210396.4546_involvedinGPIanchorattachment;C-terminusonly

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*193321___________ -1.54 -1.200.0060.0060.07310493868129875066.5033_
*196311___________ -3.77 -3.180.0010.0030.0026124216227192396.5504_hypotheticalprotein
192040___________ +1.13 +1.140.1330.5010.0742127424065242676.5979_NADPH-ferrihemoproteinreductase|nitric-oxidesynthase
191630___________ +1.09 +1.150.2070.3040.1652056322332236576.6443_
*195660___________ -1.50 -1.720.0010.0060.0023409822796198366.6899_
*196956___________ +1.74 +1.650.0010.0060.0021943533753320436.7342_allantoatepermease
193048___________ +1.21 +1.150.0300.0510.0541503618226172936.7785_hypotheticalprotein
193237___________ +1.21 +1.280.0060.0250.0101422617146182446.8236_
*195430___________ +1.11 +1.220.0110.3760.0072386026393291146.8666_hypotheticalprotein
195921___________ -1.02 -1.060.3150.2340.3881862718238175506.9115_
191438___________ +1.27 +1.160.0040.0050.0271288016407149216.155__
192404___________ +1.51 +1.540.0050.0100.0141303319702200546.666__
*191907___________ +1.18 +1.240.0040.0270.0052783932840345856.1267_
*193390___________ +1.20 +1.290.0200.0690.0253275239163421846.1811_componentofpre-mRNA3'-endprocessingfactorCFI
193899___________ +1.12 +1.100.0300.0360.0771250813968138176.2340_conservedhypotheticalprotein
*19923____________ +1.34 +1.340.0010.0030.0021984926619265776.2865_homoserinekinase
192650___________ +1.08 +1.040.1050.0720.2761219013220126286.3353_hypotheticalprotein
19839____________ +1.03 +1.030.3400.3080.3261621716770166806.3849_
*193411___________ +1.40 +1.540.0010.0060.0031532121414236076.4320_
19288____________ +1.39 +1.270.0080.0100.0351476420523187986.4817_methylenetetrahydrofolatereductase
*193002___________ -2.36 -1.940.0000.0010.0013526701492631817336.5287_ribosomalprotein10
*193575___________ +2.06 +2.270.0000.0000.0001236322545742810666.5753_
*196604___________ +1.45 +1.450.0000.0010.0011765425524255896.6216_hypotheticalprotein
*194538___________ +1.31 +1.240.0010.0020.0052605634110324216.6684_proteinwitharoleinmRNAstabilityand/orpoly(A)taillength|cleavageandpolyadenylationfactorCFIcomponentinvolvedinpre-mRNA3'-endprocessing
196871___________ +1.18 +1.280.0170.0310.0351223814437156076.7134_
196044___________ +1.00 -1.010.9530.8080.8911170511744116106.7588_proteinkinaseactivatorinvolvedincellcycleandshaperegulation
197128___________ -1.05 -1.110.0650.1300.0702050319553184966.8029_
*197084___________ +1.28 +1.420.0020.0150.0024862562083690086.8469_hypotheticalprotein
197554___________ +1.04 +1.050.2030.2340.2001386014346145816.8902_suppressorofgal11null
42944____________ -1.11 -1.100.0360.1010.0401165510509105664.2944_
*191737___________ +1.35 +1.140.0160.0100.2331322017794150956.347__hypotheticalprotein
195599___________ +1.11 +1.090.7840.5920.7261831320263200066.973__
*191084___________ +2.51 +2.290.0000.0000.0012012450465459896.1533_NOT1inhibitorofbasaltranscription
191387___________ +1.00 +1.090.6120.5940.4554985049970541666.2077_nucleotide-bindingprotein
193777___________ -1.02 +1.020.5720.3210.9191940619085197786.2593_
*191712___________ +2.02 +2.040.0000.0010.0012178043904443836.3114_GDP/GTPexchangefactorforARF
*192601___________ -1.36 -1.100.0120.0090.1533636126654329986.3598_
191762___________ +1.20 +1.150.0180.0170.0861274015338146856.4087_proteintyrosine/serinephosphatase
195681___________ -1.22 -1.080.0150.0120.1172576121043239436.4559_hypotheticalprotein
*195855___________ +1.63 +1.590.0000.0000.0003511457284558466.5047_transcriptionfactor
*196324___________ +1.20 +1.320.0060.0150.0153152137889417256.5518_
196469___________ +1.20 +1.320.0140.0290.0291388816713182656.5993_
*193446___________ +1.91 +1.990.0000.0010.0011782234081354646.6459_nuclearimportproteinthatinteractswithGTP-Gsp1p
195673___________ +1.03 -1.000.3410.1770.7151890419396189046.6913_oligopeptidetransporterprotein
194850___________ +1.01 -1.020.8400.6270.8131253412606122716.7361_conservedhypotheticalmembraneprotein
193060___________ +1.02 +1.010.6630.4310.7521342913666135326.7797_oligosaccharyltransferasedeltasubunit
193249___________ +1.04 +1.050.1410.1670.1611224312780128886.8249_longevity-assuranceprotein
195443___________ -1.17 +1.040.3200.1670.6784293436828447856.8679_kynurenine3-monooxygenase
195908___________ +1.09 +1.060.0670.0390.3201231313401130656.9130_
194463___________ +1.18 +1.120.0230.0230.0881458917287163096.29___
*192158___________ +1.02 -1.130.0400.2610.0282740827880242836.683__
*191985___________ -2.17 -2.330.0010.0040.0024069418750174786.1284_conservedhypotheticalprotein
*191751___________ +1.97 +1.760.0010.0030.0031880737013330146.1828_hypotheticalmembraneprotein
192544___________ +1.22 +1.260.0060.0160.0131608819633202696.2353_peptidyl-tRNAhydrolase
193374___________ +1.13 +1.140.0220.0660.0281307214753149176.2886_secretedcellelongationprotein
*192527___________ +2.01 +1.900.0010.0030.0031547431172294016.3370_highlyconservedhypotheticalprotein
192384___________ +1.16 +1.250.0050.0270.0071468917081183576.3864_GTPaseoftheinnermitochondrialmembrane
*193395___________ +1.45 +1.260.0040.0050.0311784425832224836.4336_highlyconservedhypotheticalprotein
64833____________ -1.05 -1.040.2090.2290.2121236411778118476.4833_
191367___________ +1.39 +1.330.0010.0030.0031693923517224606.5299_spindlebodycomponent|maydeterminemetaphasespindlelength
193561___________ +1.12 +1.090.0720.0790.1271232513828134216.5767_
196109___________ +1.17 -1.060.2610.1250.7376835279907642826.6233_
*19808____________ +2.13 +2.020.0010.0030.0021820338763367706.6699_
*196884___________ -1.37 -1.530.0000.0020.0004188430557273746.7148_membraneproteininvolvedinGPIanchorbiosynthesis
196057___________ -1.09 -1.200.0040.0330.0041877817251157126.7601_involvedincellwallbiogenesisandarchitecture
197144___________ +1.14 +1.130.0550.1250.0591342415291151136.8045_
197071___________ -1.07 -1.040.4650.3680.4481189011073114416.8482_inorganicphosphatetransporter
*197569___________ +1.53 +1.300.0010.0030.006901851383301168726.8917_nucleolarproteininvolvedinpre-rRNAprocessing
43069____________ -1.24 -1.170.0100.0190.02711546931898364.3069_
*192538___________ +3.09 +3.160.0000.0020.0011862657621588526.366__
*19735____________ +1.42 +1.220.0140.0120.1035684180718690686.996__TFIIDsubunit(TBP-associatedfactor)
*195533___________ +1.54 +1.440.0000.0010.0033187349144459856.1548_rasinhibitor;Golgitovacuoletrafficking
*19413____________ +6.37 +6.220.0000.0000.000175761118871093766.2094_hypotheticalprotein
*194133___________ +1.70 +1.830.0020.0080.0031496025453273996.2614_conservedhypotheticalprotein
*191154___________ -2.24 -2.250.0000.0000.00010741747961477836.3129_betasubunitofthenascent-polypeptide-associatedcomplex(NAC)
192435___________ +1.05 +1.080.2380.2960.2021452515231156316.3612_
*192594___________ +1.33 +1.380.0010.0030.0042332331126320876.4103_
195693___________ -1.04 +1.010.7840.7460.5892925628081294446.4574_
*195612___________ +4.87 +5.070.0000.0010.0011316364153667436.5060_
*192314___________ +1.78 +1.720.0010.0030.0021605828510276866.5536_nucleolarcoiled-coilprotein
*196452___________ -1.31 -1.310.0020.0080.0059295071015709066.6007_rapamycin-bindingprotein
*193434___________ +1.63 +1.450.0020.0040.0071578325798228656.6471_conservedhypotheticalprotein
193120___________ +1.02 -1.000.5960.3430.8841211712333120786.6925_highlyconservedhypotheticalprotein,possibleABCtransporter
*194835___________ +1.69 +1.960.0010.0040.0021920532500376636.7376_partofsmall(ribosomal)subunit(SSU)processosome(containsU3snoRNA)
*196445___________ -1.52 -1.580.0000.0020.0012999619753189806.7809_enoyl-CoAisomerase|d3,d2-Enoyl-CoAIsomerase
193263___________ +1.04 +1.040.4200.2900.4941300113476135146.8263_glyoxylatepathwayregulator
*195455___________ +2.19 +2.080.0000.0000.0003475276181721866.8691_negativeregulatorofCdc42p
195894___________ -1.03 -1.030.5220.7020.3261196011662115606.9143_conservedhypotheticalprotein
*19147____________ +2.25 +1.820.0000.0000.0012326552449422346.63___
*193599___________ +1.69 +1.740.0000.0010.0013705462755644096.702__
*195543___________ +2.45 +2.380.0010.0030.0021587938930378356.1300_
*194342___________ +3.29 +3.100.0000.0010.0011442647478447286.1848_
194637___________ +1.23 +1.170.0190.0420.0341333616340156666.2371_potentialF-boxprotein
191278___________ +1.11 +1.100.0200.0220.0721515316884166456.2901_conservedhypotheticalprotein
195053___________ +1.16 +1.080.0100.0100.0661408916378152076.3383_sisterchromatidcohesion
*193686___________ +1.58 +1.580.0000.0010.0011928830532304806.3880_F1-ATPsynthaseassemblyprotein
195501___________ +1.21 +1.070.0110.0080.1451247615078133396.4349_yeastchromatinmodifyingcomplexprotein
191714___________ +1.11 +1.050.0490.0310.2561246513794130406.4846_
*193715___________ +1.52 +1.420.0010.0010.0021691825650240576.5313_anti-silencingproteinthatcausesdepressionofsilentlociwhenoverexpressed
196354___________ +1.11 +1.060.0770.0410.3871198213349127586.5783_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
*196096___________ -1.40 -1.070.0080.0060.1096525846466610146.6244_
19823____________ +1.06 +1.020.1190.0520.7401327914059135956.6714_hypotheticalprotein
196900___________ +1.05 +1.020.1800.0810.7591225012852124776.7164_mitochondrialmorphologyanddistribution
*196070___________ +1.68 +1.350.0030.0050.0151493825076202316.7613_
*197159___________ +1.39 +1.410.0010.0040.0031992427750279966.8059_conservedhypotheticalprotein
197058___________ +1.14 +1.130.4020.2110.7751790420483201436.8495_mayberequiredfornucleardivision
197585___________ -1.13 -1.110.0350.0900.0421183910503106666.8932_
*196686___________ +1.46 +1.380.0040.0080.0151261318445174636.383__
196487___________ +1.10 +1.020.7140.4690.8051440615890147306.1019_hypotheticalprotein
192927___________ +1.06 +1.030.1450.0960.3231219012973125186.1563_mannosyltransferasecomplexcomponent
191483___________ +1.07 +1.040.2120.0950.8781523216361157906.2107_hypotheticalprotein
194981___________ +1.10 +1.070.1000.0700.2631226313537131736.2628_sodium/calciumexchangerprotein
63145____________ +1.13 +1.110.0790.0800.1461220613743135866.3145_
195537___________ +1.43 +1.210.0080.0090.0441353019362163396.3628_
195549___________ +1.05 +1.060.4630.3740.4381178712350124466.4119_
194765___________ +1.33 +1.170.0090.0080.0731255216678146846.4590_cellwallmannoprotein
191240___________ +1.13 +1.060.0430.0400.1261204713578128086.5075_
192301___________ +1.05 +1.090.1760.2180.1751711818028185896.5550_
19723____________ +1.16 +1.100.0110.0120.0571263714614138766.6021_
193674___________ -1.01 -1.040.3390.1730.7381607415953153996.6485_UDP-glucose4-epimerase
*193106___________ -1.12 +1.220.0180.1490.0153360629992409346.6939_3'-phosphoadenylylsulfatereductase
194822___________ +1.07 +1.020.1590.0740.6581189212673121166.7389_secretorylipase
196425___________ +1.28 +1.180.0040.0070.0221318816938155356.7825_
193276___________ +1.06 +1.000.3000.2080.4131352014276135646.8276_periodictryptophanprotein
195469___________ +1.01 -1.010.8820.8280.6972198622156217966.8709_
195879___________ +1.10 +1.020.1000.0480.5191231113500125156.9159_
194750___________ +1.16 +1.090.0190.0160.1051384216121150316.88___
*194145___________ +2.64 +2.170.0000.0010.0022282760327495426.720__
*192165___________ +1.42 +1.370.0020.0070.0061687123979230946.1313_conservedhypotheticalprotein
191973___________ +1.12 +1.100.0230.0250.0801542617271169526.1862_CCAAT-bindingtranscriptionfactorcomponent
*192534___________ +1.54 +1.410.0030.0080.0111551423905218456.2384_
193798___________ +1.32 +1.200.0060.0120.0211392418343166956.2916_transferRNAmethyltransferase
*195130___________ +1.36 +1.170.0050.0040.1052942839996345246.3401_proteindisulfideisomerase
*19419____________ +6.13 +5.160.0000.0010.00117244105622889486.3894_
*193501___________ +1.47 +1.330.0070.0090.0321798226478238926.4362_
195789___________ +1.04 -1.090.2200.9580.1073061631714279816.4861_phosphoribosylglycinamideformyltransferase(GART)|Nucleotidemetabolism
*196165___________ -2.50 -3.050.0000.0010.0017260429081238406.5326_alpha-ketoglutaratedehydrogenase
19999____________ +1.06 -1.010.1750.0770.8501309413879129576.5797_
*19401____________ +1.28 +1.160.0060.0080.0353132640081363526.6263_componentofchaperonin-containingT-complex
19515____________ +1.10 +1.120.0250.0470.0441496016526167786.6727_hypotheticalprotein,weaklyconserved
*196912___________ +1.61 +1.810.0000.0010.0012919846948528956.7176_ethanolaminekinase
196533___________ +1.02 -1.010.5320.3090.7571387814092137546.7627_mitochondriallysine-tRNAsynthetase
197173___________ +1.14 +1.050.0820.0560.2511283814647135276.8072_
197348___________ +1.01 +1.060.2990.4000.2181600816175169306.8508_hypotheticalprotein
197598___________ +1.04 -1.010.3350.2060.5162230623197221916.8946_AdaHistoneacetyltransferasecomplexcomponent
*194407___________ +1.90 +1.500.0000.0010.0041618630718243236.401__hypotheticalprotein
192244___________ -1.02 -1.040.6890.6790.5021195411705115116.1037_aldo/ketoreductase
191805___________ -1.03 -1.100.0420.4960.0232344122702214006.1579_
191043___________ +1.25 +1.230.0030.0070.0071244015505152696.2125_vacuolarProteinSorting
*191345___________ +2.26 +2.110.0010.0040.0041292129181272636.2643_secretedlipase
*196032___________ +1.70 +1.750.0010.0040.0021663428205290446.3160_ornithinedecarboxylase
*194184___________ +1.36 +1.280.0010.0020.0082333231847299816.3641_
*19744____________ +1.79 +1.570.0060.0150.0151419925449223296.4132_
194304___________ +1.14 +1.120.0170.0170.0761226813982137966.4607_
196010___________ +1.20 +1.120.0070.0080.0551588319112177186.5090_proteinkinaseinvolvedinregulationofDNAreplication
192668___________ +1.11 +1.080.0250.0200.1311213913467130526.5566_gag-polpolyprotein
196273___________ +1.06 +1.000.3370.1610.9151225213037123076.6032_hypotheticalprotein
19429____________ +1.14 +1.160.0250.0330.0631539617553179006.6498_topoisomeraseI-relatedprotein|Involvedinmitoticchromosomecondensation
*195181___________ +1.50 +1.430.0020.0050.0071547023260220816.6955_
*193994___________ -1.13 -1.170.0090.1060.0083316829333283326.7406_
196413___________ +1.07 +1.040.1810.1080.4191257213513130216.7841_hypotheticalprotein
195302___________ +1.00 +1.010.7500.5140.7951212812133121996.8291_
197475___________ +1.30 +1.300.0130.0310.0251250616285162646.8726_
*19178____________ +1.54 +1.410.0000.0010.0021625425100228906.120__
192680___________ +1.42 +1.190.0040.0050.0391282018212153096.740__
192761___________ +1.24 +1.160.0030.0040.0291631820217189616.1334_hypotheticalprotein
*193197___________ +1.69 +1.740.0000.0000.0002312439161403236.1880_amatinglocuspoly(A)polymerase
194821___________ +1.23 +1.130.0180.0240.0521251815400141196.2398_secretorylipase
193380___________ +1.14 +1.100.0300.0240.1381219813875133806.2934_
195200___________ +1.41 +1.200.1140.0500.7142215031165264796.3416_ser/thrproteinphosphatase
195216___________ +1.12 +1.060.0280.0150.3221353115198143926.3907_acyl-CoAthioesterase
191795___________ +1.09 +1.050.4860.4020.4412373025768249846.4374_RNA-bindingregulatorofmRNAdegradation
*191317___________ +1.50 +1.550.0010.0030.0031621024254250826.4878_
*191582___________ +1.77 +1.560.0010.0020.0071285822732200016.5338_
19984____________ +1.11 +1.080.0400.0250.2421294214396140336.5814_vacuolaralkalinephosphatase
19389____________ +1.15 +1.040.0320.0170.3481187213618123956.6275_hypotheticalprotein
19530____________ +1.19 +1.200.0040.0070.0161394816667167406.6742_hypotheticalprotein
*193294___________ +1.12 +1.320.0180.0650.0231115951250931471796.7189_multiproteinbridgingfactor
196520___________ +1.10 +1.050.0980.0490.4971237513598130106.7640_putativeallantoatepermease
*197186___________ +1.99 +1.880.0020.0040.0061453428878272806.8086_B-typecyclin
197360___________ +1.15 +1.200.0140.0420.0221406916147169196.8520_hypotheticalprotein
*197611___________ -1.23 -1.220.0240.0390.0495417944187445756.8959_thioredoxin
193099___________ -1.09 -1.070.1600.3690.1061172010787109516.416__
191438___________ +1.11 +1.060.6040.3620.8031383415344146596.1054_conservedhypotheticalprotein
193559___________ +1.08 +1.060.7840.8580.5471258213603133376.1602_conservedhypotheticalprotein
193696___________ -1.12 -1.090.0570.0540.1382741424568250716.2142_
194959___________ +1.36 +1.180.0090.0080.0961438019579170326.2657_hypotheticalprotein
19271____________ +1.05 +1.040.7000.4310.9221398814708145346.3178_short-chaindehydrogenase,2,4-dienoyl-CoAreductase
194742___________ +1.18 +1.120.0160.0230.0451252114735140316.3654_
191693___________ +1.23 +1.170.0100.0150.0371259515544147156.4147_
*191187___________ +1.82 +2.270.0000.0020.0012259041223513566.4625_
196126___________ -1.08 +1.180.3010.2490.3383119128986367506.5106_
192328___________ +1.31 +1.170.0030.0040.0261481819363172946.5580_conservedhypotheticalprotein
194946___________ +1.04 +1.030.3250.3200.2941280313254131396.6044_hypotheticalprotein
19444____________ +1.08 +1.050.0840.0600.2351250413531131186.6513_hypotheticalRNA-bindingprotein
195168___________ +1.02 +1.030.5750.3970.6091490415257152936.6968_conservedhypotheticalprotein
194005___________ +1.03 -1.000.6510.4110.7831489415295148856.7418_conservedhypotheticalprotein
196393___________ +1.15 +1.120.0140.0140.0691924722069215726.7861_transcriptionfactor
*195315___________ +1.44 +1.350.0050.0100.0131223817575164986.8304_
*197487___________ +1.64 +1.650.0010.0040.0021869430568308436.8739_reversetranscriptase

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
196399___________ -1.03 -1.060.3380.9880.1721226211872115816.164__
*194697___________ +3.10 +2.560.0000.0010.0012350172878600926.759__
191741___________ +1.34 +1.250.0050.0100.0181295417342162116.1351_
*192825___________ +1.47 +1.350.0000.0010.0023453250657466846.1898_
*193946___________ -1.29 -1.550.0050.0220.0092943022793190296.2413_cytochromecoxidaseassemblyprotein
*191199___________ +2.21 +2.080.0010.0030.0032082346117434126.2946_partofsmall(ribosomal)subunit(SSU)processosome;U3snoRNPprotein
191824___________ +1.15 +1.160.0120.0170.0361282214685148116.3431_hypotheticalprotein
192515___________ +1.53 +1.240.0910.0460.4734951475562616276.3920_hypotheticalprotein
192879___________ +1.54 +1.410.0030.0070.0081397221551197616.4389_
194783___________ +1.09 +1.070.0340.0450.0731226013360131546.4892_
*191400___________ +1.74 +1.800.0000.0020.0011648028595296066.5352_
*196376___________ -1.18 -1.410.0050.0400.0063429829056243836.5828_type2Cproteinphosphatase
*195081___________ +1.50 +1.380.0040.0080.0151959429450270866.6294_
*19542____________ +3.05 +1.930.0000.0000.0001947645935603766236.6754_hexokinaseII
*193307___________ +1.32 +1.170.0080.0090.0522192429008255566.7202_monooxygenase
196507___________ +1.04 +1.020.1100.0500.6241518415810155106.7653_curvedDNA-bindingprotein
197199___________ +1.29 +1.240.0050.0080.0201402618119173756.8099_conservedhypotheticalprotein
197372___________ +1.30 +1.240.0080.0160.0211388618017172436.8532_transcriptionfactor
197624___________ -1.01 +1.020.6020.3930.6861279812712130226.8971_
192266___________ +1.42 +1.350.0020.0030.0071477721048199756.436__
*196081___________ +1.21 +1.180.0120.0110.0812523573051772980736.1067_
194904___________ +1.13 +1.150.0210.0300.0541292814629148716.1619_actin-relatedprotein
191268___________ +1.04 +1.110.0260.0810.0311401414520154876.2160_hypotheticalprotein
193166___________ +1.10 +1.090.0410.0350.1351232013545133696.2673_
194728___________ +1.34 +1.280.0070.0120.0231331417894170966.3190_
*192397___________ +3.58 +4.120.0010.0020.0021376049205567106.3676_highaffinitynicotinicacidplasmamembranepermease
191374___________ +1.12 +1.050.0490.0280.3211218213635128416.4160_hypotheticalprotein
*193555___________ +2.31 +2.180.0010.0020.0031543635641336576.4646_conservedhypotheticalprotein
196232___________ -1.01 +1.130.1530.7910.0753138131177353656.5124_
191943___________ +1.37 +1.460.0000.0020.0011511020773220426.5596_hypotheticalprotein
194163___________ +1.07 +1.050.1690.1210.3111218512981127746.6057_conservedhypotheticalprotein
196630___________ +1.19 +1.160.0070.0120.0261304715462150876.6528_
195156___________ +1.09 +1.060.0680.0390.3371243013509132336.6980_conservedhypotheticalmembraneprotein
194018___________ -1.07 -1.120.0330.1420.0291214911337108776.7431_putativemitochondrialribosomalproteinS7
194578___________ +1.01 -1.010.6140.4160.6611532515479151166.7877_cytochromec1hemelyase
*195328___________ +1.43 +1.510.0000.0010.0012394934358361576.8318_
197500___________ +1.17 +1.070.0420.0280.2121184413842126726.8752_subunitofperoxisomalATP-bindingcassettetransporter
194760___________ +1.38 +1.270.0020.0050.0121435119837182766.179__conservedhypotheticalprotein
192012___________ +1.23 +1.110.0090.0090.0641283815825142076.777__
192295___________ -1.07 +1.030.9220.9790.7239471988204979936.1367_CTA2.5
193493___________ +1.41 +1.360.0020.0040.0081369419296186336.1911_C-14sterolreductase
*194951___________ +1.53 +1.610.0000.0020.0011607024632258386.2432_hypotheticalprotein
19190____________ +1.29 +1.260.0090.0300.0151365717558171666.2963_conservedhypotheticalprotein
191164___________ -1.10 +1.020.3170.1600.7314864244057494596.3445_nucleolarrRNAprocessingprotein
195302___________ +1.24 +1.070.0110.0060.4031260415678134356.3933_
193196___________ +1.06 +1.040.1110.0580.4511374714583142626.4404_
*195727___________ +1.57 +1.560.0000.0000.0003095948645481466.4906_hypotheticalprotein
*192132___________ +1.18 +1.100.0260.0150.2973025235823331846.5366_hypotheticalprotein
193876___________ +1.11 +1.100.0270.0260.0941227813572134616.5847_putativeinvolvementinmaltosefermentation
*194396___________ -1.94 -1.900.0010.0020.00215972282309840456.6310_
6677_____________ +1.04 +1.040.2100.1140.5131261813064131256.6770_
193320___________ +1.05 +1.020.2200.1290.4581242013100126816.7215_hypotheticalprotein
*195275___________ +1.34 +1.330.0050.0080.0181582521265209886.7667_conservedhypotheticalprotein
*197210___________ +1.24 +1.170.0050.0060.0322597832140305136.8111_
*197384___________ +2.55 +2.860.0010.0030.0021440636695412246.8544_nucleolarG-protein
*197638___________ +1.20 +1.330.0110.0910.0112966235720393046.8986_gamma-glutamylkinase
196610___________ +1.06 -1.020.5770.3360.8161281813605125786.455__
191595___________ +1.10 +1.020.1860.3830.1241799619855183096.1081_conservedhypotheticalprotein
193077___________ +1.14 +1.060.0510.0240.5441321515022139426.1635_
191140___________ -1.01 +1.050.8160.8560.5881623416102171056.2176_hypotheticalprotein
19243____________ -1.05 +1.000.6570.3880.9731979218792198246.2689_
194076___________ +1.22 +1.140.0140.0120.0911196814612136006.3204_sulfitereductaseflavin-bindingsubunit
19688____________ -1.27 -1.120.0250.0260.0882365418619211226.3691_mitochondrialribosomalsmallsubunitprotein
195480___________ +1.12 +1.150.0120.0350.0201633218255187036.4176_
*195495___________ +1.34 +1.430.0000.0010.0002364931727337486.4662_negativeregulatorofdifferentiation
193908___________ +1.34 +1.280.0020.0050.0071329817794170046.5140_hypotheticalprotein
191844___________ +1.17 +1.070.0480.0310.2361224614352131226.5613_
194179___________ +1.02 +1.010.6750.4050.9701176011938119126.6072_
*196644___________ +1.63 +1.800.0010.0050.0031625926490292026.6541_hypotheticalprotein
196845___________ +1.11 +1.060.0430.0260.2501267814045134126.6994_hypotheticalprotein
*194033___________ +1.28 +1.300.0030.0070.0081884224029245796.7446_RNA-dependentATPase
194592___________ +1.06 +1.090.1280.5730.0681441815315157006.7891_ceramideglucosyltransferase
*195343___________ +1.96 +1.940.0010.0030.0051604131413310536.8333_
197513___________ -1.25 -1.100.0060.0050.1202715521663246586.8765_n-alkaneinduciblecytochromeP-450
19194____________ -1.05 -1.060.3750.4340.2801225811658115736.197__hypotheticalprotein
*191911___________ +1.46 +1.440.0000.0010.0011020941495251472396.800__
191302___________ +1.38 +1.270.0030.0050.0191423119621180356.1385_
*193357___________ -2.22 -2.910.0000.0010.0006911131162237106.1926_involvedintoxinresistance
*192288___________ +2.89 +2.480.0000.0020.0012275965852564246.2448_T-complexprotein1,epsilonsubunit
1911053__________ +1.08 +1.080.0710.0820.1191198512953129726.2981_NA
*192919___________ +2.38 +2.040.0010.0030.0041636538880334276.3459_RNAhelicaseinvolvedinDNArepair
19911____________ +1.06 -1.250.1680.9860.0806545469305525026.3949_E3ubiqitinligaserequiredforG2/Mtransition
*195584___________ +1.40 +1.230.0000.0010.0024266659834524746.4426_vacuolarmembraneprotein
*191069___________ +1.60 +1.780.0000.0010.001652841041431160806.4920_RegulatoryParticleNon-ATPase
*192149___________ +1.51 +1.390.0010.0050.0031496322553208166.5382_
193890___________ +1.28 +1.270.0070.0130.0201527419553193466.5863_
194383___________ +1.32 +1.150.0040.0060.0181518120049174056.6324_conservedhypotheticalprotein
66784____________ +1.50 +1.330.0020.0060.0071498422415199986.6784_
19345____________ +1.02 -1.000.5160.2780.9161559015929155306.7229_succinatesemialdehydedehydrogenase
195262___________ +1.08 +1.090.0440.0450.1111251013472136916.7680_hypotheticalprotein
*197224___________ +2.48 +2.690.0000.0030.0011578339152424846.8124_conservedhypotheticalprotein
*197396___________ +1.33 +1.390.0060.0140.0141491519856206576.8556_hypotheticalprotein
*197655___________ -1.03 -1.280.0230.9740.0122316632251461809996.9004_
*19223____________ +1.59 +1.470.0010.0030.0032111433631309906.476__
61099____________ +1.11 +1.070.0390.0240.2561290714359137476.1099_
*191600___________ +1.15 +1.170.0010.0040.0033842444288449436.1649_hypotheticalprotein
193720___________ +1.10 +1.010.1060.0590.3993280836170332636.2193_potentialcyclicnucleotidebindingdomain
*193631___________ +1.66 +1.580.0060.0150.0151702828205268936.2707_
191031___________ -1.15 -1.050.1100.1540.1234293237472408596.3220_3-hydroxy-3-methyl-glutarylcoenzymeAreductase(HMG-CoA)
1995_____________ +1.13 +1.060.0430.0260.2631234513975130716.3707_hypotheticalprotein

factorfactorpvaluepvaluepvaluemedian_fitted_datamedian_fitted_datamedian_fitted_datagene annotationgene annotation
condition1condition2multiclasscontrol vers. condition1control vers. condition2condition0(CONTROL)condition1condition2functional categorydescription
Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B) Complemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)ControlComplemented strains (MEP2MK1a and -B)mep2Δ mutants (MEP2M5A and -B)
194498___________ +1.26 +1.190.0050.0100.0151407217777167786.4190_hypotheticalprotein
*192579___________ +1.48 +1.520.0060.0120.0161515522456230226.4678_
*19220____________ +1.88 +2.750.0000.0000.00046684878311284846.5152_
*19329____________ +1.03 +1.160.0240.1980.0183876639897449636.5629_splicingbranchpointbridgingprotein
*192179___________ +2.39 +3.460.0000.0040.0011322431665457906.6084_iron-siderophoretransporter
19665____________ +1.11 +1.020.6630.4590.6853655440431372016.6558_involvedinribosomesmallsubunitbiogenesis
196856___________ +1.33 +1.340.0060.0140.0141263316747169136.7006_
*192097___________ +1.75 +1.760.0010.0040.0022085036390367136.7458_ATPase/DNAhelicase
194606___________ +1.18 +1.160.0050.0080.0231782821037206806.7905_phosphomevalonatekinase|involvedinergosterolbiosynthesispathway
195362___________ -1.03 -1.010.9070.7380.8261207211760119036.8350_
*197529___________ +2.01 +1.970.0000.0010.0012813156628554906.8782_
*195620___________ +1.95 +1.480.0000.0000.0012445947616360866.212__conservedhypotheticalprotein
193923___________ +1.22 +1.160.0060.0090.0311303615924150976.822__
*192518___________ +1.15 +1.200.0030.0160.0065432862351654036.1399_transportvesiclefusionprotein
193496___________ +1.28 +1.180.0170.0270.0431257416109148846.1941_
*193607___________ +2.52 +2.540.0010.0030.0031456236652369296.2463_alpha/betahydrolase
19794____________ +1.12 +1.070.6510.6680.4621577517712169326.2994_cyclin-dependentserine/threoninproteinkinase|componentofRNApolymeraseIIholoenzyme
191122___________ +1.01 -1.020.4680.3330.5091401114154136716.3474_
191516___________ +1.29 +1.380.0020.0060.0041503419446206976.3967_
*19302____________ +1.74 +1.830.0000.0020.0011644128664300406.4440_ERtogolgitransportcomponentofTRAPP
*191055___________ +3.46 +3.660.0000.0000.000349701209491280776.4934_septin|cellcycle|involvedinproperbudgrowth
*196177___________ -1.15 -1.040.0470.0260.3173345329075323126.5398_hypotheticalprotein
193138___________ +1.02 +1.070.7270.7300.5222541325864270876.5874_
*195110___________ +1.48 +1.490.0010.0040.0041510822298225486.6341_
*196691___________ +1.77 +2.070.0000.0000.0002605146105539666.6800_ethionineresistanceprotein
19357____________ -1.07 -1.110.0320.3130.0201194111151107496.7242_
*195250___________ -1.86 -1.970.0010.0020.0025829231397296436.7692_predictedCoA-bindingprotein
*197238___________ +1.47 +1.730.0000.0010.0005346478719922556.8138_nucleolarshuttlingproteinwithanRNArecognitionmotif
*197410___________ +1.30 +1.330.0020.0120.0043449645002459026.8570_metalloprotease
*197670___________ +1.28 +1.390.0050.0130.0114246954182590736.9019_
193212___________ +1.50 +1.260.0060.0070.0421445921663182506.496__
195741___________ +1.09 +1.000.9210.9050.7341347314647135316.1115_
19773____________ +1.26 +1.120.0260.0230.1151279816080143876.1670_
195539___________ +1.15 +1.120.0280.0590.0431522417557170456.2207_
194433___________ +1.13 +1.080.1090.0880.2181191113465129126.2724_
191732___________ +1.27 +1.190.0060.0120.0191242215821147536.3233_U3snoRNPprotein
192796___________ +1.09 +1.030.1350.0760.4171236013429127776.3725_DNApolymerasealpha-primasecomplexBsubuni
*192346___________ +1.38 +1.560.0020.0100.0041360318833212146.4206_highlyconservedhypotheticalprotein
192735___________ +1.12 +1.150.0060.0210.0111869520967214466.4691_tRNAsplicingendonucleasebetasubunit
*192426___________ +2.03 +1.860.0010.0030.0031472529940273826.5167_conservedhypotheticalprotein
19315____________ +1.07 +1.220.0550.2990.0362357025282287526.5643_hypotheticalprotein
193425___________ +1.07 +1.130.1340.2200.1202354025163265476.6100_conservedhypotheticalprotein
19677____________ +1.05 +1.090.1510.1050.3061494615642162276.6571_
191902___________ +1.22 +1.140.0070.0120.0231643320035186896.7018_nucleolarU3snoRNPprotein
192082___________ +1.03 -1.000.3940.1960.9191230312726122776.7473_Gpi-anchoredasparticprotease
*194618___________ -1.58 -1.580.0030.0050.0153030871916751919846.7918_
*197282___________ +1.25 +1.180.0030.0050.0171978824763234266.8363_peroxisomeimportprotein-peroxin
197545___________ +1.16 +1.100.0270.0340.0691712919944188096.8797_hypotheticalprotein